DK0388019T3 - Avermectin-ketal-derivater, der er egnede som antiparasitiske midler - Google Patents

Avermectin-ketal-derivater, der er egnede som antiparasitiske midler

Info

Publication number: DK0388019T3
Authority: DK; Denmark
Prior art keywords: avermectin; antiparasitic agents; derivatives useful; ketal; ketal derivatives
Prior art date: 1989-02-16

Application number

DK90301638.4T

Other languages

English (en)

Inventor

Timothy A Blizzard

Original Assignee

Merck & Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-02-16

Filing date

1990-02-15

Publication date

1994-05-24

1990-02-15 Application filed by Merck & Co Inc filed Critical Merck & Co Inc

1994-05-24 Application granted granted Critical

1994-05-24 Publication of DK0388019T3 publication Critical patent/DK0388019T3/da

Links

239000005660 Abamectin Substances 0.000 title abstract 3
239000003096 antiparasitic agent Substances 0.000 title abstract 2
229940125687 antiparasitic agent Drugs 0.000 title abstract 2
RRZXIRBKKLTSOM-XPNPUAGNSA-N avermectin B1a Chemical compound C1=C[C@H](C)[C@@H]([C@@H](C)CC)O[C@]11O[C@H](C\C=C(C)\[C@@H](O[C@@H]2O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](OC)C3)[C@@H](OC)C2)[C@@H](C)\C=C\C=C/2[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\2)O)C[C@H]4C1 RRZXIRBKKLTSOM-XPNPUAGNSA-N 0.000 title abstract 2
TWCMVXMQHSVIOJ-UHFFFAOYSA-N Aglycone of yadanzioside D Natural products COC(=O)C12OCC34C(CC5C(=CC(O)C(O)C5(C)C3C(O)C1O)C)OC(=O)C(OC(=O)C)C24 TWCMVXMQHSVIOJ-UHFFFAOYSA-N 0.000 abstract 1
PLMKQQMDOMTZGG-UHFFFAOYSA-N Astrantiagenin E-methylester Natural products CC12CCC(O)C(C)(CO)C1CCC1(C)C2CC=C2C3CC(C)(C)CCC3(C(=O)OC)CCC21C PLMKQQMDOMTZGG-UHFFFAOYSA-N 0.000 abstract 1
238000007385 chemical modification Methods 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
PFOARMALXZGCHY-UHFFFAOYSA-N homoegonol Natural products C1=C(OC)C(OC)=CC=C1C1=CC2=CC(CCCO)=CC(OC)=C2O1 PFOARMALXZGCHY-UHFFFAOYSA-N 0.000 abstract 1
150000002576 ketones Chemical class 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics

Landscapes

Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Dentistry (AREA)
Engineering & Computer Science (AREA)
Plant Pathology (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Environmental Sciences (AREA)
Agronomy & Crop Science (AREA)
Veterinary Medicine (AREA)
Pest Control & Pesticides (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Tropical Medicine & Parasitology (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Saccharide Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

DK90301638.4T 1989-02-16 1990-02-15 Avermectin-ketal-derivater, der er egnede som antiparasitiske midler DK0388019T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US31126889A	1989-02-16	1989-02-16

Publications (1)

Publication Number	Publication Date
DK0388019T3 true DK0388019T3 (da)	1994-05-24

Family

ID=23206158

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK90301638.4T DK0388019T3 (da)	1989-02-16	1990-02-15	Avermectin-ketal-derivater, der er egnede som antiparasitiske midler

Country Status (11)

Country	Link
US (1)	US5077308A (da)
EP (1)	EP0388019B1 (da)
JP (1)	JPH02270880A (da)
AT (1)	ATE104983T1 (da)
AU (1)	AU623744B2 (da)
CA (1)	CA2010078A1 (da)
DE (1)	DE69008399T2 (da)
DK (1)	DK0388019T3 (da)
ES (1)	ES2063256T3 (da)
NZ (1)	NZ232422A (da)
ZA (1)	ZA901148B (da)

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US20120329832A1 (en)	2011-06-27	2012-12-27	Jean Delaveau	Novel Insect-Repellent Coumarin Derivatives, Syntheses, and Methods of Use
ES2618813T3 (es)	2011-06-27	2017-06-22	Merial, Inc.	Compuestos y composiciones de éter amido-piridílico y uso contra los parásitos
RS58417B1 (sr)	2011-09-12	2019-04-30	Merial Inc	Paraziticidne kompozicije koje sadrže izoksazolinsko aktivno sredstvo, postupci i upotrebe povezane sa njima
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BR112014013371B1 (pt)	2011-12-02	2020-04-07	Merial Ltd	formulações de moxidectina injetável de ação prolongada e novas formas de cristal de moxidectina
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BR122015032741B1 (pt)	2012-04-20	2019-11-26	Merial Ltd	composições parasiticídicas compreendendo derivados de benzimidazol, métodos e seus usos
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ES2842592T3 (es)	2014-05-19	2021-07-14	Boehringer Ingelheim Animal Health Usa Inc	Compuestos antihelmínticos
EP3157912B1 (en)	2014-06-19	2019-02-20	Merial, Inc.	Parasiticidal compositions comprising indole derivatives, methods and uses thereof
US10864193B2 (en)	2014-10-31	2020-12-15	Boehringer Ingelheim Animal Health USA Inc.	Parasiticidal compositions comprising fipronil at high concentrations
UY36570A (es)	2015-02-26	2016-10-31	Merial Inc	Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas
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LT3298027T (lt)	2015-05-20	2021-08-10	Boehringer Ingelheim Animal Health USA Inc.	Antihelmintiniai depsipeptido junginiai
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WO2018039508A1 (en)	2016-08-25	2018-03-01	Merial, Inc.	Method for reducing unwanted effects in parasiticidal treatments
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BR112020003217A2 (pt)	2017-08-14	2020-10-06	Boehringer Ingelheim Animal Health USA Inc.	compostos pesticidas e parasiticidas de pirazolisoxazolina
EP3749096A1 (en)	2018-02-08	2020-12-16	Boehringer Ingelheim Animal Health USA Inc.	Parasiticidal compositions comprising eprinomectin and praziquantel, methods and uses thereof
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1990
- 1990-02-08 NZ NZ232422A patent/NZ232422A/xx unknown
- 1990-02-14 CA CA002010078A patent/CA2010078A1/en not_active Abandoned
- 1990-02-15 ZA ZA901148A patent/ZA901148B/xx unknown
- 1990-02-15 DK DK90301638.4T patent/DK0388019T3/da active
- 1990-02-15 AU AU49830/90A patent/AU623744B2/en not_active Ceased
- 1990-02-15 EP EP90301638A patent/EP0388019B1/en not_active Expired - Lifetime
- 1990-02-15 DE DE69008399T patent/DE69008399T2/de not_active Expired - Fee Related
- 1990-02-15 AT AT9090301638T patent/ATE104983T1/de active
- 1990-02-15 ES ES90301638T patent/ES2063256T3/es not_active Expired - Lifetime
- 1990-02-16 JP JP2034038A patent/JPH02270880A/ja active Pending
- 1990-07-23 US US07/556,044 patent/US5077308A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
ZA901148B (en)	1990-10-31
ES2063256T3 (es)	1995-01-01
AU4983090A (en)	1991-08-29
EP0388019A1 (en)	1990-09-19
JPH02270880A (ja)	1990-11-05
US5077308A (en)	1991-12-31
AU623744B2 (en)	1992-05-21
CA2010078A1 (en)	1990-08-16
DE69008399T2 (de)	1994-10-27
NZ232422A (en)	1992-11-25
EP0388019B1 (en)	1994-04-27
ATE104983T1 (de)	1994-05-15
DE69008399D1 (de)	1994-06-01

Publication	Publication Date	Title
DK0388019T3 (da)	1994-05-24	Avermectin-ketal-derivater, der er egnede som antiparasitiske midler
IL89921A0 (en)	1989-12-15	1,3-dioxolane derivatives and pharmaceutical compositions containing the same
IL112055A0 (en)	1995-03-15	Guar as drift control agent
NO991152D0 (no)	1999-03-10	Stabil farmas°ytisk blanding inneholdende 4,5-epoksy-morfinan-derivat
ES2079633T3 (es)	1996-01-16	Composiciones solidas de glifosato y su uso.
EP0401010A3 (en)	1991-05-02	Pyranyl cyanoguanidine derivatives
ATE173738T1 (de)	1998-12-15	Alkylthioalkylavermectine sind aktive antiparasitäre wirkstoffe
FI913769A0 (fi)	1991-08-08	Nya tricykliska foereningar eller deras salter, foerfarande foer deras framstaellning och dessa innehaollande antimikrobiellt medel.
ATE237359T1 (de)	2003-05-15	Zyklodextrin-zusammensetzung enthaltend ein avermectin- oder ein milbemycin-derivat
ES2164660T3 (es)	2002-03-01	Derivados difluoro de avermectina.
DK436784A (da)	1985-03-14	Beta-butyrolacton-derivater, fremgangsmaade til deres fremstilling samt immunomodulerende midler indeholdende disse derivater som aktive bestanddele
ATE90685T1 (de)	1993-07-15	Disaccharidderivate.
PT1197207E (pt)	2008-07-01	Composições estáveis para administração parentérica
ATE118012T1 (de)	1995-02-15	2'-deoxy-2'-methylidenecytidin-dihydrat, verfahren zu ihrer herstellung und mischmaterial.
ATE98239T1 (de)	1993-12-15	2,5,6,7-tetranor-4,8-inter-m-phenylen-pgi2derivate.
DE3880088D1 (de)	1993-05-13	Ethylierte avermectine.
DZ1435A1 (fr)	2004-09-13	Synthèse asymétrique des dérivés de la furo Ä3,4-cÜpyridine.
HUT56579A (en)	1991-09-30	Process for producing 19-norprogesterone derivatives alkylated at 17/21 position, as well as pharmaceutical compositions comprising such compounds as active ingredient
NO903066L (no)	1991-01-11	Fremgangsmaate for fremstilling av 5,6-dihydro(1h-indolo(3,2-c)quinolin-6,4-piperidin) og beslektede forbindelser, samt anvendelse som medikamenter.
IL103856A0 (en)	1993-04-04	Aminoalkyl-substituted 5,6-dihydro-dibenz(b,e)azepin-6,11-dione-11-oximes,their preparation and pharmaceutical compositions containing them
HUT52111A (en)	1990-06-28	Process for producing cytidine-5'-diphosphatealkanols and -glycerine derivatives, as well pharmaceutical compositions comprising such compounds as active ingredient
FI921475A7 (fi)	1992-04-03	1,4-dihydro-4-okso-3-kinoliinijohdannaisia selektiivisesti toksisina n isäkkään antibakteerisina aineina
DK558188A (da)	1990-04-07	Acetylerede pseudoammoniak-, pseudourinstof- eller guanidinderivater, egnede som aktivatorer for oxiderende blegemidler