ATE104983T1 - Avermectin-ketal-derivate, die als antiparasitenmittel geeignet sind. - Google Patents

Avermectin-ketal-derivate, die als antiparasitenmittel geeignet sind.

Info

Publication number: ATE104983T1
Authority: AT; Austria
Prior art keywords: avermectin; antiparasitic agents; derivatives useful; ketal; ketal derivatives
Prior art date: 1989-02-16

Application number

AT9090301638T

Other languages

English (en)

Inventor

Timothy A Blizzard

Original Assignee

Merck & Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-02-16

Filing date

1990-02-15

Publication date

1994-05-15

1990-02-15 Application filed by Merck & Co Inc filed Critical Merck & Co Inc

1994-05-15 Application granted granted Critical

1994-05-15 Publication of ATE104983T1 publication Critical patent/ATE104983T1/de

Links

239000005660 Abamectin Substances 0.000 title abstract 3
239000003096 antiparasitic agent Substances 0.000 title abstract 2
229940125687 antiparasitic agent Drugs 0.000 title abstract 2
RRZXIRBKKLTSOM-XPNPUAGNSA-N avermectin B1a Chemical compound C1=C[C@H](C)[C@@H]([C@@H](C)CC)O[C@]11O[C@H](C\C=C(C)\[C@@H](O[C@@H]2O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](OC)C3)[C@@H](OC)C2)[C@@H](C)\C=C\C=C/2[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\2)O)C[C@H]4C1 RRZXIRBKKLTSOM-XPNPUAGNSA-N 0.000 title abstract 2
TWCMVXMQHSVIOJ-UHFFFAOYSA-N Aglycone of yadanzioside D Natural products COC(=O)C12OCC34C(CC5C(=CC(O)C(O)C5(C)C3C(O)C1O)C)OC(=O)C(OC(=O)C)C24 TWCMVXMQHSVIOJ-UHFFFAOYSA-N 0.000 abstract 1
PLMKQQMDOMTZGG-UHFFFAOYSA-N Astrantiagenin E-methylester Natural products CC12CCC(O)C(C)(CO)C1CCC1(C)C2CC=C2C3CC(C)(C)CCC3(C(=O)OC)CCC21C PLMKQQMDOMTZGG-UHFFFAOYSA-N 0.000 abstract 1
238000007385 chemical modification Methods 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
PFOARMALXZGCHY-UHFFFAOYSA-N homoegonol Natural products C1=C(OC)C(OC)=CC=C1C1=CC2=CC(CCCO)=CC(OC)=C2O1 PFOARMALXZGCHY-UHFFFAOYSA-N 0.000 abstract 1
150000002576 ketones Chemical class 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics

Landscapes

Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Dentistry (AREA)
Environmental Sciences (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Engineering & Computer Science (AREA)
Plant Pathology (AREA)
Pest Control & Pesticides (AREA)
Veterinary Medicine (AREA)
Agronomy & Crop Science (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Tropical Medicine & Parasitology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Saccharide Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

AT9090301638T 1989-02-16 1990-02-15 Avermectin-ketal-derivate, die als antiparasitenmittel geeignet sind. ATE104983T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US31126889A	1989-02-16	1989-02-16

Publications (1)

Publication Number	Publication Date
ATE104983T1 true ATE104983T1 (de)	1994-05-15

Family

ID=23206158

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT9090301638T ATE104983T1 (de)	1989-02-16	1990-02-15	Avermectin-ketal-derivate, die als antiparasitenmittel geeignet sind.

Country Status (11)

Country	Link
US (1)	US5077308A (de)
EP (1)	EP0388019B1 (de)
JP (1)	JPH02270880A (de)
AT (1)	ATE104983T1 (de)
AU (1)	AU623744B2 (de)
CA (1)	CA2010078A1 (de)
DE (1)	DE69008399T2 (de)
DK (1)	DK0388019T3 (de)
ES (1)	ES2063256T3 (de)
NZ (1)	NZ232422A (de)
ZA (1)	ZA901148B (de)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL119649A (en) *	1995-11-30	2002-03-10	Akzo Nobel Nv	Preparation of Cyclic Kills of History - 3 keto- (5) 10, (-9) 11 steroidadians
ME00855B (me) *	1997-12-03	2008-08-07	Merck & Co Inc	Injektibilne formulacije dugog dejstva koje sadrže hidrogenisano ricinusovo ulje
US6733767B2 (en)	1998-03-19	2004-05-11	Merck & Co., Inc.	Liquid polymeric compositions for controlled release of bioactive substances
US6787342B2 (en)	2000-02-16	2004-09-07	Merial Limited	Paste formulations
US7001889B2 (en) *	2002-06-21	2006-02-21	Merial Limited	Anthelmintic oral homogeneous veterinary pastes
US20060205681A1 (en) *	2002-06-21	2006-09-14	Maryam Moaddeb	Homogenous paste formulations
US20040077703A1 (en) *	2002-10-02	2004-04-22	Soll Mark D.	Nodulisporic acid derivative spot-on formulations for combating parasites
US7531186B2 (en)	2003-12-17	2009-05-12	Merial Limited	Topical formulations comprising 1-N-arylpyrazole derivatives and amitraz
US8362086B2 (en)	2005-08-19	2013-01-29	Merial Limited	Long acting injectable formulations
US20080027011A1 (en) *	2005-12-20	2008-01-31	Hassan Nached	Homogeneous paste and gel formulations
CA2656617C (en)	2006-07-05	2014-10-14	Aventis Agriculture	1-aryl-5-alkyl pyrazole derivative compounds, processes of making and methods of using thereof
US8901163B2 (en)	2007-01-03	2014-12-02	Galderma S.A.	Method of treating hyperesthesia, paresthesia, dolor, and pruritus caused by insect stings or noxious weeds or plants using avermectin compound
ES2597083T3 (es)	2007-05-15	2017-01-13	Merial, Inc.	Compuestos de ariloazol-2-il cianoetilamino, procedimiento de fabricación y procedimiento de utilización de los mismos
CA2706448C (en)	2007-11-26	2016-08-16	Merial Limited	Solvent systems for pour-on formulations for combating parasites
ES2584930T3 (es)	2007-12-21	2016-09-30	Merial Limited	El uso de compuestos de 6-halógeno-(1,2,4)-triazolo-(1,5-a)-pirimidina para combatir plagas en y sobre animales
NZ590141A (en) *	2008-06-24	2012-05-25	Merial Ltd	Anthelminthic formulations including castor oil and another vegetable oil
MY153715A (en)	2008-11-14	2015-03-13	Merial Ltd	Enantiomerically enriched aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof
US9173728B2 (en)	2008-11-19	2015-11-03	Merial Inc.	Multi-cavity container having offset indentures for dispensing fluids
ES2781828T3 (es)	2008-11-19	2020-09-08	Boehringer Ingelheim Animal Health Usa Inc	Composiciones que comprenden un aril pirazol y/o una formamidina, procedimientos y usos de las mismas
JP5595412B2 (ja)	2008-12-04	2014-09-24	メリアルリミテッド	二量体アベルメクチン及びミルベマイシン誘導体
BR112012002164B1 (pt)	2009-07-30	2021-04-20	Merial, Inc	compostos inseticidas de 4-amino-tieno[2,3-d]-pirimidina e métodos para seu uso
ES2546100T3 (es)	2009-12-04	2015-09-18	Merial, Inc.	Compuestos pesticidas bis-organosulfurados
EP3078664B1 (de)	2009-12-17	2019-02-20	Merial Inc.	Antiparasitäre dihydroazol zusammensetzungen
NZ600845A (en)	2009-12-17	2014-08-29	Merial Ltd	Compositions comprising macrocyclic lactone compounds and spirodioxepinoindoles
UA108641C2 (uk)	2010-04-02	2015-05-25		Паразитицидна композиція, яка містить чотири активних агенти, та спосіб її застосування
PT2568980E (pt)	2010-05-12	2016-03-15	Merial Inc	Formulações parasiticidas injectáveis de levamisole e lactonas macrocíclicas
US8912151B2 (en)	2010-10-20	2014-12-16	Galderma S.A.	Method of treating hemorrhoids using macrocyclic lactone compound
US8901090B2 (en)	2010-10-20	2014-12-02	Galderma S.A.	Method of treating otitis externa using macrocyclic lactone compound
NZ610547A (en)	2010-11-16	2015-07-31	Merial Ltd	Novel monensin derivatives for the treatment and prevention of protozoal infections
WO2012078605A1 (en)	2010-12-07	2012-06-14	Merial Limited	Topical combination formulations of macrocyclic lactones with synthetic pyrethroids
ES2618813T3 (es)	2011-06-27	2017-06-22	Merial, Inc.	Compuestos y composiciones de éter amido-piridílico y uso contra los parásitos
WO2013003168A1 (en)	2011-06-27	2013-01-03	Merial Limited	Novel insect-repellent coumarin derivatives, syntheses, and methods of use
PL3172964T3 (pl)	2011-09-12	2021-03-08	Boehringer Ingelheim Animal Health USA Inc.	Kompozycje przeciwpasożytniczne zawierające izoksazolinową substancję czynną, sposób i ich zastosowania
US20130079394A1 (en)	2011-09-23	2013-03-28	Cnrs (Centre National Recherche Scientifique)	Indirect modeling of new repellent molecules active against insects, acarids, and other arthropods
CN104023720B (zh)	2011-11-17	2016-10-26	梅里亚有限公司	包含芳基吡唑和取代咪唑的组合物，其方法和用途
EP3351546B9 (de)	2011-12-02	2024-07-10	Boehringer Ingelheim Vetmedica GmbH	Langwirkende injizierbare moxidectinformulierungen
LT2811998T (lt)	2012-02-06	2019-02-25	Merial, Inc.	Paraziticidinės peroralinės veterinarinės kompozicijos, apimančios sistemiškai veikiančius aktyviuosius agentus, būdai ir jų panaudojimas
JO3626B1 (ar)	2012-02-23	2020-08-27	Merial Inc	تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها
NZ701185A (en)	2012-04-20	2015-08-28	Merial Ltd	Parasiticidal compositions comprising benzimidazole derivatives, methods and uses thereof
PL2922845T3 (pl)	2012-11-20	2018-11-30	Merial, Inc.	Związki przeciwrobacze oraz ich kompozycje i sposób stosowania
SMT201800309T1 (it)	2013-01-31	2018-07-17	Merial Inc	Metodo per trattare e curare leishmaniosi utilizzando fexinidazolo
DK3063144T3 (da)	2013-11-01	2021-10-25	Boehringer Ingelheim Animal Health Usa Inc	Antiparasitære og pesticid-isoxazolinforbindelser
BR112016023898A8 (pt)	2014-04-17	2021-03-30	Basf Se	uso de compostos malononitrila para proteger animais de parasitas
CA2949511A1 (en)	2014-05-19	2015-11-26	Merial, Inc.	Anthelmintic compounds
CN106536481B (zh)	2014-06-19	2019-11-22	勃林格殷格翰动物保健美国公司	包含吲哚衍生物的杀寄生物的组合物、其用法和用途
WO2016069983A1 (en)	2014-10-31	2016-05-06	Merial, Inc.	Parasiticidal composition comprising fipronil
UY36570A (es)	2015-02-26	2016-10-31	Merial Inc	Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas
EA036272B1 (ru)	2015-04-08	2020-10-21	БЁРИНГЕР ИНГЕЛЬХАЙМ ЭНИМАЛ ХЕЛТ ЮЭсЭй ИНК.	Инъецируемые препараты замедленного высвобождения, содержащие изоксазолиновое действующее вещество, способы и применение
CN107835818B (zh)	2015-05-20	2022-04-29	勃林格殷格翰动物保健美国公司	驱虫缩酚酸肽化合物
EP3303385A2 (de)	2015-05-27	2018-04-11	Merial, Inc.	Zusammensetzungen mit antimikrobiellen igy-antikörpern zur behandlung und prävention von störungen und erkrankungen durch die mundgesundheit beeinträchtigende mikroorganismen
UY40429A (es)	2016-02-24	2023-10-13	Boehringer Ingelheim Animal Health Usa Inc	Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos
WO2018039508A1 (en)	2016-08-25	2018-03-01	Merial, Inc.	Method for reducing unwanted effects in parasiticidal treatments
AU2017344097A1 (en)	2016-10-14	2019-05-02	Boehringer Ingelheim Animal Health USA Inc.	Pesticidal and parasiticidal vinyl isoxazoline compounds
EP3541789A1 (de)	2016-11-16	2019-09-25	Boehringer Ingelheim Animal Health USA Inc.	Anthelmintische depsipeptidverbindungen
US11147273B2 (en)	2017-06-26	2021-10-19	Boehringer Ingelheim Animal Health USA Inc.	Dual active parasiticidal granule compositions, methods and uses thereof
MX2020001724A (es)	2017-08-14	2020-07-29	Boehringer Ingelheim Animal Health Usa Inc	Compuestos de pirazol-isoxazolina plaguicidas y parasiticidas.
US11583545B2 (en)	2018-02-08	2023-02-21	Boehringer Ingelheim Animal Health USA Inc.	Parasiticidal compositions comprising eprinomectin and praziquantel, methods and uses thereof
US12269822B2 (en)	2018-07-09	2025-04-08	Boehringer Ingelheim Animal Health USA Inc.	Anthelminthic heterocyclic compounds
WO2020112374A1 (en)	2018-11-20	2020-06-04	Boehringer Ingelheim Animal Health USA Inc.	Indazolylcyanoethylamino compound, compositions of same, method of making, and methods of using thereof
WO2020150032A1 (en)	2019-01-16	2020-07-23	Boehringer Ingelheim Animal Health USA Inc.	Topical compositions comprising a neonicotinoid and a macrocyclic lactone, methods and uses thereof
UY38599A (es)	2019-03-01	2020-08-31	Boehringer Ingelheim Animal Health Usa Inc	Composiciones inyectables de clorsulón, sus métodos y usos
MX2021011302A (es)	2019-03-19	2022-01-19	Boehringer Ingelheim Animal Health Usa Inc	Compuestos de aza-benzotiofeno y aza-benzofurano como antihelminticos.
EP4003292A1 (de)	2019-07-22	2022-06-01	Intervet International B.V.	Weiche, kaubare tierarzneiform
KR20230028268A (ko)	2020-05-29	2023-02-28	뵈링거 잉겔하임 애니멀 헬스 유에스에이 인코포레이티드	구충성 헤테로시클릭 화합물
CN116897044A (zh)	2020-12-21	2023-10-17	勃林格殷格翰动物保健有限公司	包含异噁唑啉化合物的杀寄生虫环
WO2025257633A1 (en)	2024-06-12	2025-12-18	Boehringer Ingelheim Vetmedica Gmbh	Long-acting castor oil-containing injectable formulations and methods of use thereof

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3950360A (en) *	1972-06-08	1976-04-13	Sankyo Company Limited	Antibiotic substances
SE434277B (sv) *	1976-04-19	1984-07-16	Merck & Co Inc	Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
USRE32006E (en) *	1977-12-19	1985-10-15	Merck & Co., Inc.	13-Halo and 13-deoxy C-076 compounds
USRE32032E (en) *	1978-02-10	1985-11-19	Foam Cutting Engineers, Inc.	Method of densifying open-celled polyurethane material
US4200581A (en) *	1978-08-04	1980-04-29	Merck & Co., Inc.	Alkyl derivatives of C-076 compounds
JPS59108785A (ja) *	1982-11-25	1984-06-23	Sankyo Co Ltd	ミルベマイシン類の５−オキシム誘導体
DE3519834C2 (de) *	1984-06-05	1993-12-16	American Cyanamid Co	Neue antibiotische Wirkstoffe, Verfahren zu ihrer Gewinnung und ihre Anwendung zur Bekämpfung von Infektionen bei Tieren und Pflanzen
PL152148B1 (en) *	1984-09-14	1990-11-30	Glaxo Group Ltd	Antibiotic compounds and their preparation
HUT39739A (en) *	1984-12-04	1986-10-29	Ciba Geigy Ag	Process for production of derivatives of 13,3-milbemycin and medical preparatives containing thereof
DE3750495T2 (de) *	1986-07-24	1995-02-23	Beecham Group Plc	Milbemycin-Derivate mit parasitenabtötender Aktivität, ein Verfahren zu ihrer Herstellung und die sie enthaltenden Zusammensetzungen.
EP0277916B1 (de) *	1987-02-04	1994-05-25	Ciba-Geigy Ag	Mikrobielles Verfahren zur Herstellung von Milbemycin-Derivaten
US4871719A (en) *	1987-03-24	1989-10-03	Ciba-Geigy Corporation	Composition for controlling parasites in productive livestock

1990
- 1990-02-08 NZ NZ232422A patent/NZ232422A/xx unknown
- 1990-02-14 CA CA002010078A patent/CA2010078A1/en not_active Abandoned
- 1990-02-15 ZA ZA901148A patent/ZA901148B/xx unknown
- 1990-02-15 DK DK90301638.4T patent/DK0388019T3/da active
- 1990-02-15 EP EP90301638A patent/EP0388019B1/de not_active Expired - Lifetime
- 1990-02-15 AT AT9090301638T patent/ATE104983T1/de active
- 1990-02-15 ES ES90301638T patent/ES2063256T3/es not_active Expired - Lifetime
- 1990-02-15 DE DE69008399T patent/DE69008399T2/de not_active Expired - Fee Related
- 1990-02-15 AU AU49830/90A patent/AU623744B2/en not_active Ceased
- 1990-02-16 JP JP2034038A patent/JPH02270880A/ja active Pending
- 1990-07-23 US US07/556,044 patent/US5077308A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
AU4983090A (en)	1991-08-29
JPH02270880A (ja)	1990-11-05
EP0388019A1 (de)	1990-09-19
US5077308A (en)	1991-12-31
EP0388019B1 (de)	1994-04-27
ES2063256T3 (es)	1995-01-01
AU623744B2 (en)	1992-05-21
CA2010078A1 (en)	1990-08-16
NZ232422A (en)	1992-11-25
DE69008399D1 (de)	1994-06-01
ZA901148B (en)	1990-10-31
DK0388019T3 (da)	1994-05-24
DE69008399T2 (de)	1994-10-27

Publication	Publication Date	Title
ATE104983T1 (de)	1994-05-15	Avermectin-ketal-derivate, die als antiparasitenmittel geeignet sind.
DE69623764D1 (de)	2002-10-24	1,3-propandiol-derivate als bioaktive verbindungen
EP0632725A4 (de)	1997-03-19	Alkylthioalkylavermectine sind aktive antiparasitäre wirkstoffe.
ATE162796T1 (de)	1998-02-15	4-a-substutierte avermectinderivate
EP0401010A3 (de)	1991-05-02	Pyranyl-cyanoguanidin-Derivate
ZA916268B (en)	1992-04-29	Tricyclic compound or salts thereof,method for producing the same and antimicrobial agent containing the same
ES2164660T3 (es)	2002-03-01	Derivados difluoro de avermectina.
DE68913950D1 (de)	1994-04-21	Stabilisierte, Schwefel lösende Zusammensetzungen.
OA09847A (fr)	1994-08-15	dérivés d'epipodophyllotoxine altroside
IL93733A0 (en)	1990-12-23	Antitumor and antibacterial substituted disulfide derivatives prepared from compounds possessing a methyl-trithio group,and targeted forms thereof
ATE118012T1 (de)	1995-02-15	2'-deoxy-2'-methylidenecytidin-dihydrat, verfahren zu ihrer herstellung und mischmaterial.
ATE90685T1 (de)	1993-07-15	Disaccharidderivate.
FI916018A7 (fi)	1992-06-21	1,3-dioksolaanijohdannaisia kolesterolia alentavina aineina
FI905350A0 (fi)	1990-10-30	Komposition innehaollande maerkta streptokock-antikroppar,testfoerpackning och analysfoerfarande, i vilket den anvaends.
DK0627443T3 (da)	1997-09-15	3,4-dideoxymycaminosyltylonolidderivat og fremstilling deraf
ATE85185T1 (de)	1993-02-15	1,4-naphthochinonderivate enthaltende rodentizide zusammensetzungen.
DE69007775D1 (de)	1994-05-05	5'-alkylphosphonylnukleoside als antivirale verbindungen.
DZ1435A1 (fr)	2004-09-13	Synthèse asymétrique des dérivés de la furo Ä3,4-cÜpyridine.
DE69116057D1 (de)	1996-02-15	Mikrobische Herstellung des 13-beta-13-deoxy-22,23,-dihydroavermectin-Bla/B1b-Aglycons
DK0544168T3 (da)	1998-04-14	Anvendelse af aminoalkyl-substituerede 5,6-dihydro-dibenz(b,e) azepin-6,11-dion-11-oximer som antivirale midler
FI921475A7 (fi)	1992-04-03	1,4-dihydro-4-okso-3-kinoliinijohdannaisia selektiivisesti toksisina n isäkkään antibakteerisina aineina
ATE93140T1 (de)	1993-09-15	Spironolakton zusammensetzungen.
IT8921610A0 (it)	1989-09-04	Procedimento per la preparazione di 2,3 diidro 2,2 dimetilbenzofuran 7 olo.
NO884264L (no)	1988-09-27	3'-azido-2',3'-dideoksyuridin-anti-retrovirus-blanding.