DK164280C - 1h-imidazooe4,5-caaquinolin eller derivat deraf og farmaceutisk praeparat indeholdende en saadan forbindelse - Google Patents
1h-imidazooe4,5-caaquinolin eller derivat deraf og farmaceutisk praeparat indeholdende en saadan forbindelseInfo
- Publication number
- DK164280C DK164280C DK542684A DK542684A DK164280C DK 164280 C DK164280 C DK 164280C DK 542684 A DK542684 A DK 542684A DK 542684 A DK542684 A DK 542684A DK 164280 C DK164280 C DK 164280C
- Authority
- DK
- Denmark
- Prior art keywords
- carbon atoms
- imidazooe4
- caaquinoline
- derivative
- connection
- Prior art date
Links
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 5
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- ITIRVXDSMXFTPW-UHFFFAOYSA-N 1H-imidazo[4,5-c]quinoline Chemical class C1=CC=CC2=C(NC=N3)C3=CN=C21 ITIRVXDSMXFTPW-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 125000004210 cyclohexylmethyl group Chemical group [H]C([H])(*)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Physical Water Treatments (AREA)
- Macromonomer-Based Addition Polymer (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Quinoline Compounds (AREA)
- Alarm Systems (AREA)
- Lubricants (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Luminescent Compositions (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55315883A | 1983-11-18 | 1983-11-18 | |
| US55315783A | 1983-11-18 | 1983-11-18 | |
| US55315783 | 1983-11-18 | ||
| US55315883 | 1983-11-18 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| DK542684D0 DK542684D0 (da) | 1984-11-15 |
| DK542684A DK542684A (da) | 1985-05-19 |
| DK164280B DK164280B (da) | 1992-06-01 |
| DK164280C true DK164280C (da) | 1992-11-30 |
Family
ID=27070262
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK542684A DK164280C (da) | 1983-11-18 | 1984-11-15 | 1h-imidazooe4,5-caaquinolin eller derivat deraf og farmaceutisk praeparat indeholdende en saadan forbindelse |
| DK135891A DK164455C (da) | 1983-11-18 | 1991-07-16 | 1h-imidazooe4,5-caaquinolin-4-chlorforbindelser |
| DK135791A DK169179B1 (da) | 1983-11-18 | 1991-07-16 | 1H-imidazo[4,5-c]quinolin-4-amin, farmaceutisk præparat indeholdende en sådan forbindelse og fremga ngsmåde til fremstilling af en sådan forbindelse |
| DK136091A DK164451C (da) | 1983-11-18 | 1991-07-16 | 3-aminoquinolinderivat |
| DK135991A DK165921C (da) | 1983-11-18 | 1991-07-16 | 1h-imidazooe4,5-caaquinolin-5-oxyforbindelser |
| DK136191A DK164452C (da) | 1983-11-18 | 1991-07-16 | 3-nitroquinolinderivat |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK135891A DK164455C (da) | 1983-11-18 | 1991-07-16 | 1h-imidazooe4,5-caaquinolin-4-chlorforbindelser |
| DK135791A DK169179B1 (da) | 1983-11-18 | 1991-07-16 | 1H-imidazo[4,5-c]quinolin-4-amin, farmaceutisk præparat indeholdende en sådan forbindelse og fremga ngsmåde til fremstilling af en sådan forbindelse |
| DK136091A DK164451C (da) | 1983-11-18 | 1991-07-16 | 3-aminoquinolinderivat |
| DK135991A DK165921C (da) | 1983-11-18 | 1991-07-16 | 1h-imidazooe4,5-caaquinolin-5-oxyforbindelser |
| DK136191A DK164452C (da) | 1983-11-18 | 1991-07-16 | 3-nitroquinolinderivat |
Country Status (15)
| Country | Link |
|---|---|
| EP (2) | EP0310950B1 (fr) |
| JP (1) | JPS60123488A (fr) |
| KR (1) | KR900005657B1 (fr) |
| AT (2) | ATE84525T1 (fr) |
| AU (2) | AU581190B2 (fr) |
| CA (1) | CA1271477A (fr) |
| DE (3) | DE3486043T2 (fr) |
| DK (6) | DK164280C (fr) |
| ES (1) | ES8603477A1 (fr) |
| IE (1) | IE57874B1 (fr) |
| IL (2) | IL84537A (fr) |
| NL (2) | NL980043I1 (fr) |
| NO (7) | NO163819C (fr) |
| NZ (1) | NZ210228A (fr) |
| PH (1) | PH22338A (fr) |
Families Citing this family (74)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1306260C (fr) * | 1985-10-18 | 1992-08-11 | Shionogi & Co., Ltd. | Derives imidazopyridine condenses |
| US4942168A (en) * | 1987-07-13 | 1990-07-17 | Hoechst-Roussel Pharmaceuticals Inc. | Hydroxyquinoline amines, and method of enhancing memory in mammals |
| CA1335996C (fr) * | 1988-02-16 | 1995-06-20 | Susumu Takada | Carbonylimidazo(4,5)quinolines substituees en position 2 |
| EP0361489A3 (fr) * | 1988-09-30 | 1991-06-12 | Chugai Seiyaku Kabushiki Kaisha | Composés de 3,4-diaminoquinoline et de pyridine |
| DK0385630T3 (da) * | 1989-02-27 | 1997-05-12 | Riker Laboratories Inc | 1H-imidazo(4,5-c)quinolin-4-aminer som antivirale midler |
| CA2011504C (fr) * | 1989-03-07 | 1998-06-02 | Kenji Ohmori | Derives d'imidazolquinolone |
| US4929624A (en) * | 1989-03-23 | 1990-05-29 | Minnesota Mining And Manufacturing Company | Olefinic 1H-imidazo(4,5-c)quinolin-4-amines |
| CA2021338C (fr) * | 1989-07-18 | 1996-07-16 | Fumio Suzuki | Derives d'imidazoquinolone |
| US4988815A (en) * | 1989-10-26 | 1991-01-29 | Riker Laboratories, Inc. | 3-Amino or 3-nitro quinoline compounds which are intermediates in preparing 1H-imidazo[4,5-c]quinolines |
| FR2654021B1 (fr) * | 1989-11-07 | 1992-02-28 | Simond Jacques | Procede de vitrification de cendres volantes et dispositif pour sa mise en óoeuvre. |
| GB8928281D0 (en) * | 1989-12-14 | 1990-02-21 | Smith Kline French Lab | Compounds |
| CA2043715C (fr) * | 1990-06-01 | 1997-01-07 | Fumio Suzuki | Derives d'imidazonaphtyridine |
| UA32546C2 (uk) * | 1991-03-01 | 2001-02-15 | Міннесота Майнінг Енд Мен'Юфекчурінг Компані | 1,2-заміщені 1н-імідазо[4,5-с]хінолін-4-аміни, проміжні сполуки для їх синтезу, антивірусна фармацевтична композиція, спосіб лікування інфікованих ссавців, спосіб індукування біосинтезу інтерферону у ссавців, спосіб уповільнення росту бластом |
| US5266575A (en) * | 1991-11-06 | 1993-11-30 | Minnesota Mining And Manufacturing Company | 2-ethyl 1H-imidazo[4,5-ciquinolin-4-amines |
| IL105325A (en) * | 1992-04-16 | 1996-11-14 | Minnesota Mining & Mfg | Immunogen/vaccine adjuvant composition |
| US5395937A (en) * | 1993-01-29 | 1995-03-07 | Minnesota Mining And Manufacturing Company | Process for preparing quinoline amines |
| US5693811A (en) * | 1996-06-21 | 1997-12-02 | Minnesota Mining And Manufacturing Company | Process for preparing tetrahdroimidazoquinolinamines |
| WO1998030562A1 (fr) * | 1997-01-09 | 1998-07-16 | Terumo Kabushiki Kaisha | Nouveaux derives d'amide et intermediaires utilises pour leur synthese |
| JPH10298181A (ja) * | 1997-04-25 | 1998-11-10 | Sumitomo Pharmaceut Co Ltd | タイプ2ヘルパーt細胞選択的免疫応答抑制剤 |
| JP2000119271A (ja) * | 1998-08-12 | 2000-04-25 | Hokuriku Seiyaku Co Ltd | 1h―イミダゾピリジン誘導体 |
| UA74852C2 (en) * | 2000-12-08 | 2006-02-15 | 3M Innovative Properties Co | Urea-substituted imidazoquinoline ethers |
| EP2332922A1 (fr) * | 2001-10-23 | 2011-06-15 | Merck Serono S.A. | Azoles N-substitués et leur utilisation en tant que modulateurs de MEK-1 et/ou ERK-2 |
| GB0211649D0 (en) | 2002-05-21 | 2002-07-03 | Novartis Ag | Organic compounds |
| KR20050028047A (ko) | 2002-07-23 | 2005-03-21 | 비오갈 기오기스제르갸르 알티. | 1h-이미다조[4,5-c]퀴놀린-4-프탈이미드 중간체를 통한1h-이미다조[4,5-c]퀴놀린-4-아민의 제조 |
| ATE357445T1 (de) | 2002-07-26 | 2007-04-15 | Teva Gyogyszergyar Zartkoeruee | Darstellung von 1h-imidazo(4,5-c)chinolin-4- aminen über neue 1h-imidazo(4,5-c)chinolin-4- cyano- und 1h-imidazo(4,5-c)chinolin-4-carboxamid intermediate |
| AR045260A1 (es) | 2003-08-12 | 2005-10-19 | 3M Innovative Properties Co | Compuestos que contienen imidazo-oxima sustituidos |
| AU2004268625B2 (en) * | 2003-08-27 | 2011-03-31 | 3M Innovative Properties Company | Aryloxy and arylalkyleneoxy substituted imidazoquinolines |
| CA2537763A1 (fr) | 2003-09-05 | 2005-03-17 | 3M Innovative Properties Company | Traitement pour le lymphome a cellules b cd5<sp>+</sp> |
| CA2536530A1 (fr) | 2003-10-01 | 2005-04-14 | Taro Pharmaceuticals U.S.A., Inc. | Procede de preparation de 4-amino-1h-imidazo(4,5-c)quinolines et sels d'ajout acides de celles-ci |
| EP1673087B1 (fr) | 2003-10-03 | 2015-05-13 | 3M Innovative Properties Company | Imidazoquinolines a substitution alcoxy |
| US7544697B2 (en) | 2003-10-03 | 2009-06-09 | Coley Pharmaceutical Group, Inc. | Pyrazolopyridines and analogs thereof |
| ITMI20032121A1 (it) * | 2003-11-04 | 2005-05-05 | Dinamite Dipharma Spa In Forma Abbr Eviata Dipharm | Procedimento per la preparazione di imiquimod e suoi intermedi |
| CA2545774A1 (fr) | 2003-11-14 | 2005-06-02 | 3M Innovative Properties Company | Composes d'un anneau d'imidazo substitues par oxime |
| JP2007511535A (ja) | 2003-11-14 | 2007-05-10 | スリーエム イノベイティブ プロパティズ カンパニー | ヒドロキシルアミン置換イミダゾ環化合物 |
| EP1687307B1 (fr) | 2003-11-25 | 2016-01-06 | 3M Innovative Properties Company | Systemes cycliques d'imidazo substitues et procedes |
| WO2005066170A1 (fr) | 2003-12-29 | 2005-07-21 | 3M Innovative Properties Company | Imidazoquinolines a substitution arylalcenyle et arylalkynyle |
| CA2551399A1 (fr) | 2003-12-30 | 2005-07-21 | 3M Innovative Properties Company | Sulfonamides d'imidazoquinolinyle, d'imidazopyridinyle et d'imidazonaphtyridinyle |
| US8697873B2 (en) | 2004-03-24 | 2014-04-15 | 3M Innovative Properties Company | Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines |
| WO2005123080A2 (fr) | 2004-06-15 | 2005-12-29 | 3M Innovative Properties Company | Imidazoquinolines et imidazonaphthyridines substituees par un heterocyclyle contenant un azote |
| US7897609B2 (en) | 2004-06-18 | 2011-03-01 | 3M Innovative Properties Company | Aryl substituted imidazonaphthyridines |
| WO2006009826A1 (fr) | 2004-06-18 | 2006-01-26 | 3M Innovative Properties Company | Thiazoloquinolines et thiazolonaphtyridines substitues par aryloxy et arylalkyleneoxy |
| US7915281B2 (en) | 2004-06-18 | 2011-03-29 | 3M Innovative Properties Company | Isoxazole, dihydroisoxazole, and oxadiazole substituted imidazo ring compounds and method |
| AU2005326708C1 (en) | 2004-12-30 | 2012-08-30 | 3M Innovative Properties Company | Substituted chiral fused [1,2]imidazo[4,5-c] ring compounds |
| EP1831226B1 (fr) | 2004-12-30 | 2012-08-08 | 3M Innovative Properties Company | Composes chiraux tetracycliques incitant la biosynthese d'interferon |
| WO2006084251A2 (fr) | 2005-02-04 | 2006-08-10 | Coley Pharmaceutical Group, Inc. | Formulations des gel aqueux contenant des modificateurs de reponse immunitaire |
| WO2006086634A2 (fr) | 2005-02-11 | 2006-08-17 | Coley Pharmaceutical Group, Inc. | Composes cycliques imidazo[4,5-c] substitues par oxime et hydroxylamine et procedes associes |
| US7943610B2 (en) | 2005-04-01 | 2011-05-17 | 3M Innovative Properties Company | Pyrazolopyridine-1,4-diamines and analogs thereof |
| EP1863814A1 (fr) | 2005-04-01 | 2007-12-12 | Coley Pharmaceutical Group, Inc. | Composes cycliques 1-pyrazolo (3,4-c) substitues comme modulateurs de la biosynthese de cytokine destines au traitement d'infections virales et de maladies neoplastiques |
| ES2577514T3 (es) | 2005-08-22 | 2016-07-15 | The Regents Of The University Of California | Antagonistas de TLR |
| US8846697B2 (en) | 2006-05-31 | 2014-09-30 | The Regents Of The University Of California | Purine analogs |
| US7906506B2 (en) | 2006-07-12 | 2011-03-15 | 3M Innovative Properties Company | Substituted chiral fused [1,2] imidazo [4,5-c] ring compounds and methods |
| DK2510946T3 (en) | 2007-02-07 | 2015-11-02 | Univ California | Conjugates of synthetic fluorescent agonists and their applications |
| EP2009002A1 (fr) * | 2007-06-21 | 2008-12-31 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Nouveau procédé pour la fabrication de systèmes d'anneau de quinoléine 1H-imidazo [4,5-c] |
| WO2010088924A1 (fr) | 2009-02-06 | 2010-08-12 | Telormedix Sa | Compositions pharmaceutiques comprenant des imidazoquinolines (amines) et des dérivés de celles-ci appropriés pour une administration locale |
| EP2396328A2 (fr) | 2009-02-11 | 2011-12-21 | The Regents of The University of California | Modulateurs des recepteurs de type toll et traitement de maladies |
| CA2808624C (fr) | 2010-08-17 | 2019-05-14 | 3M Innovative Properties Company | Compositions lipidisees de composes modifiant la reponse immunitaire, formulations et procedes associes |
| US8728486B2 (en) | 2011-05-18 | 2014-05-20 | University Of Kansas | Toll-like receptor-7 and -8 modulatory 1H imidazoquinoline derived compounds |
| IN2014KN00948A (fr) | 2011-10-04 | 2015-08-21 | Janus Biotherapeutics Inc | |
| CA3102531A1 (fr) * | 2013-02-01 | 2014-08-07 | Wellstat Therapeutics Corporation | Composes de quinazoline-4-amine substitues et leurs compositions pharmaceutiques ayant une activite anti-inflammatoire, antifongique, antiparasitaire et anticancereuse |
| CN105189495A (zh) * | 2013-03-15 | 2015-12-23 | 先正达参股股份有限公司 | 新颖的杀微生物剂 |
| ES2538880B1 (es) * | 2013-12-24 | 2016-09-08 | Laboratorios Viñas S.A. | Un procedimiento para obtener 4-amino-1-isobutil-1H-imidazo[4,5-c]quinoleína |
| JP2017503803A (ja) | 2014-01-10 | 2017-02-02 | シャンハイ バーディー バイオテック インコーポレイテッド | Egfr発現腫瘍を処置するための化合物及び組成物 |
| EP3166976B1 (fr) | 2014-07-09 | 2022-02-23 | Birdie Biopharmaceuticals Inc. | Combinaisons anti-pd-l1 pour le traitement des tumeurs |
| MX377305B (es) * | 2015-09-14 | 2025-03-07 | Pfizer | DERIVADOS DE IMIDAZO[4,5-c]QUINOLINA E IMIDAZO[4,5-c][1,5]NAFTIRIDINA NOVEDOSOS COMO INHIBIDORES DE LRRK2. |
| CN106943596A (zh) | 2016-01-07 | 2017-07-14 | 博笛生物科技(北京)有限公司 | 用于治疗肿瘤的抗-cd20组合 |
| CN106943597A (zh) | 2016-01-07 | 2017-07-14 | 博笛生物科技(北京)有限公司 | 用于治疗肿瘤的抗-egfr组合 |
| WO2017184735A1 (fr) * | 2016-04-19 | 2017-10-26 | Ifm Therapeutics, Inc | Modulateurs de nlrp3 |
| KR20180134395A (ko) | 2016-04-19 | 2018-12-18 | 인네이트 튜머 이뮤니티, 인코포레이티드 | Nlrp3 조정제 |
| US11697851B2 (en) | 2016-05-24 | 2023-07-11 | The Regents Of The University Of California | Early ovarian cancer detection diagnostic test based on mRNA isoforms |
| TWI674261B (zh) | 2017-02-17 | 2019-10-11 | 美商英能腫瘤免疫股份有限公司 | Nlrp3 調節劑 |
| CN108794467A (zh) | 2017-04-27 | 2018-11-13 | 博笛生物科技有限公司 | 2-氨基-喹啉衍生物 |
| CA3067268A1 (fr) | 2017-06-23 | 2018-12-27 | Birdie Biopharmaceuticals, Inc. | Anhydrate de monosulfate de resiquimod cristallin, preparation et utilisations |
| FR3113287B1 (fr) | 2020-08-07 | 2023-06-23 | Phv Pharma | Procédé industriel de synthèse de l’imiquimod à partir de la quinolèine-2,4-diol applicable à son utilisation pharmaceutique |
| KR20230118101A (ko) * | 2020-12-09 | 2023-08-10 | 웰스태트 테러퓨틱스 코포레이션 | 항염증, 항진균, 항기생충 및 항암 활성을 갖는 이미다조퀴놀린 화합물 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3700674A (en) * | 1969-04-30 | 1972-10-24 | American Cyanamid Co | 4-alkylamino-3-nitroquinolines |
| RO86850B (ro) * | 1982-05-03 | 1985-05-31 | Eli Lilly And Company | Procedeu pentru prepararea unor 2-fenilimidazo [4,5 c] piridine |
-
1984
- 1984-11-13 CA CA000467706A patent/CA1271477A/fr not_active Expired - Lifetime
- 1984-11-14 AU AU35402/84A patent/AU581190B2/en not_active Expired
- 1984-11-15 DK DK542684A patent/DK164280C/da not_active IP Right Cessation
- 1984-11-15 NO NO844565A patent/NO163819C/no not_active IP Right Cessation
- 1984-11-15 ES ES537677A patent/ES8603477A1/es not_active Expired
- 1984-11-16 EP EP88116137A patent/EP0310950B1/fr not_active Expired - Lifetime
- 1984-11-16 PH PH31451A patent/PH22338A/en unknown
- 1984-11-16 AT AT88116137T patent/ATE84525T1/de not_active IP Right Cessation
- 1984-11-16 IE IE2952/84A patent/IE57874B1/en not_active IP Right Cessation
- 1984-11-16 IL IL84537A patent/IL84537A/xx not_active IP Right Cessation
- 1984-11-16 DE DE8888116137T patent/DE3486043T2/de not_active Expired - Lifetime
- 1984-11-16 EP EP84307974A patent/EP0145340B1/fr not_active Expired - Lifetime
- 1984-11-16 AT AT84307974T patent/ATE49763T1/de active
- 1984-11-16 NZ NZ210228A patent/NZ210228A/xx unknown
- 1984-11-16 DE DE8484307974T patent/DE3481124D1/de not_active Expired - Lifetime
- 1984-11-16 DE DE1999175027 patent/DE19975027I2/de active Active
- 1984-11-17 KR KR1019840007224A patent/KR900005657B1/ko not_active Expired
- 1984-11-17 JP JP59243142A patent/JPS60123488A/ja active Granted
-
1987
- 1987-11-19 IL IL84537A patent/IL84537A0/xx unknown
-
1989
- 1989-02-14 AU AU29911/89A patent/AU611997B2/en not_active Expired
- 1989-02-27 NO NO890823A patent/NO165146C/no not_active IP Right Cessation
- 1989-02-27 NO NO890824A patent/NO165147C/no not_active IP Right Cessation
- 1989-02-27 NO NO890826A patent/NO168705C/no not_active IP Right Cessation
- 1989-02-27 NO NO890822A patent/NO165145C/no not_active IP Right Cessation
- 1989-02-27 NO NO890825A patent/NO169437C/no not_active IP Right Cessation
-
1991
- 1991-07-16 DK DK135891A patent/DK164455C/da not_active IP Right Cessation
- 1991-07-16 DK DK135791A patent/DK169179B1/da not_active IP Right Cessation
- 1991-07-16 DK DK136091A patent/DK164451C/da not_active IP Right Cessation
- 1991-07-16 DK DK135991A patent/DK165921C/da not_active IP Right Cessation
- 1991-07-16 DK DK136191A patent/DK164452C/da not_active IP Right Cessation
-
1998
- 1998-12-14 NL NL980043C patent/NL980043I1/nl unknown
- 1998-12-14 NL NL980041C patent/NL980041I2/nl unknown
-
1999
- 1999-07-08 NO NO1999015C patent/NO1999015I1/no unknown
Also Published As
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| DK164280C (da) | 1h-imidazooe4,5-caaquinolin eller derivat deraf og farmaceutisk praeparat indeholdende en saadan forbindelse |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUP | Patent expired |