DK36196A - Muterede subtilisin-gener - Google Patents

Muterede subtilisin-gener Download PDF

Info

Publication number: DK36196A
Authority: DK; Denmark
Prior art keywords: amino acid; enzyme; mutant; sequence shown; acid sequence
Prior art date: 1988-01-07

Application number

DK036196A

Other languages

English (en)

Other versions

DK176102B1 (da

Inventor

Sven Hastrup

Sven Branner

Fanny Norris

Steffen B Petersen

Leif Noerskov-Lauritsen

Villy Johannes Jensen

Dorrit Aaslyng

Original Assignee

Novo Nordisk As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-01-07

Filing date

1996-03-29

Publication date

1996-03-29

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8089323&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK36196(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1996-03-29 Application filed by Novo Nordisk As filed Critical Novo Nordisk As

1996-03-29 Priority to DK199600361A priority Critical patent/DK176102B1/da

1996-03-29 Publication of DK36196A publication Critical patent/DK36196A/da

2006-06-12 Application granted granted Critical

2006-06-12 Publication of DK176102B1 publication Critical patent/DK176102B1/da

Links

108090000787 Subtilisin Proteins 0.000 title abstract 4
125000000539 amino acid group Chemical group 0.000 abstract 3
125000003275 alpha amino acid group Chemical group 0.000 abstract 2
108090000790 Enzymes Proteins 0.000 abstract 1
102000004190 Enzymes Human genes 0.000 abstract 1
108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
108020004511 Recombinant DNA Proteins 0.000 abstract 1
RKLXDNHNLPUQRB-TVJUEJKUSA-N chembl564271 Chemical compound C([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]2C(C)SC[C@H](N[C@@H](CC(N)=O)C(=O)NC(=O)[C@@H](NC2=O)CSC1C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NC(=C)C(=O)N[C@@H](CCCCN)C(O)=O)NC(=O)[C@H]1NC(=O)C(=C\C)/NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H]2NC(=O)CNC(=O)[C@@H]3CCCN3C(=O)[C@@H](NC(=O)[C@H]3N[C@@H](CC(C)C)C(=O)NC(=O)C(=C)NC(=O)CC[C@H](NC(=O)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CC=4C5=CC=CC=C5NC=4)CSC3)C(O)=O)C(C)SC2)C(C)C)C(C)SC1)C1=CC=CC=C1 RKLXDNHNLPUQRB-TVJUEJKUSA-N 0.000 abstract 1
230000037430 deletion Effects 0.000 abstract 1
238000012217 deletion Methods 0.000 abstract 1
230000037431 insertion Effects 0.000 abstract 1
238000003780 insertion Methods 0.000 abstract 1
108010082567 subtilin Proteins 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
- C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Wood Science & Technology (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
Zoology (AREA)
General Engineering & Computer Science (AREA)
Oil, Petroleum & Natural Gas (AREA)
Biotechnology (AREA)
Biomedical Technology (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Microbiology (AREA)
Enzymes And Modification Thereof (AREA)
Detergent Compositions (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Amplifiers (AREA)
Saccharide Compounds (AREA)
Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

DK199600361A 1988-01-07 1996-03-29 Muterede subtilisin-gener DK176102B1 (da)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
DK199600361A DK176102B1 (da)	1988-01-07	1996-03-29	Muterede subtilisin-gener

Applications Claiming Priority (6)

Application Number	Priority Date	Filing Date	Title
DK6488		1988-01-07
DK006488A DK6488D0 (da)	1988-01-07	1988-01-07	Enzymer
DK161290		1990-07-04
DK199001612A DK175697B1 (da)	1988-01-07	1990-07-04	Muterede subtilisin-gener
DK36196		1996-03-29
DK199600361A DK176102B1 (da)	1988-01-07	1996-03-29	Muterede subtilisin-gener

Publications (2)

Publication Number	Publication Date
DK36196A true DK36196A (da)	1996-03-29
DK176102B1 DK176102B1 (da)	2006-06-12

Family

ID=8089323

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
DK006488A DK6488D0 (da)	1988-01-07	1988-01-07	Enzymer
DK199001612A DK175697B1 (da)	1988-01-07	1990-07-04	Muterede subtilisin-gener
DK199600361A DK176102B1 (da)	1988-01-07	1996-03-29	Muterede subtilisin-gener

Family Applications Before (2)

Application Number	Title	Priority Date	Filing Date
DK006488A DK6488D0 (da)	1988-01-07	1988-01-07	Enzymer
DK199001612A DK175697B1 (da)	1988-01-07	1990-07-04	Muterede subtilisin-gener

Country Status (7)

Country	Link
US (6)	US6506589B1 (da)
EP (4)	EP0675196A3 (da)
JP (3)	JPH0675504B2 (da)
AT (1)	ATE136329T1 (da)
DE (1)	DE68926163T2 (da)
DK (3)	DK6488D0 (da)
WO (1)	WO1989006279A1 (da)

Families Citing this family (755)

* Cited by examiner, † Cited by third party
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JPH04500384A (ja) *	1989-06-26	1992-01-23	ユニリーバー・ナームローゼ・ベンノートシヤープ	酵素洗剤組成物
DK316989D0 (da) *	1989-06-26	1989-06-26	Novo Nordisk As	Enzymer
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ATE187490T1 (de) *	1989-08-25	1999-12-15	Henkel Research Corp	Alkalisches proteolytisches enzym und verfahren zur herstellung
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DE4023458A1 (de) *	1989-08-31	1991-03-07	Kali Chemie Ag	Neue hochalkalische proteasen
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US5541062A (en) *	1990-02-23	1996-07-30	Arch Development Corporation	Methods and compositions for preparing protein processing enzymes
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FI932832A7 (fi) *	1990-12-21	1993-08-13	Novozymes As	Entsyymimutantteja, joilla on alhainen molekyylivarauksen vaihteluaste pH-alueella
GB9027836D0 (en) *	1990-12-21	1991-02-13	Unilever Plc	Enzymes and enzymatic detergent compositions
US5482849A (en) *	1990-12-21	1996-01-09	Novo Nordisk A/S	Subtilisin mutants
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US5646028A (en) *	1991-06-18	1997-07-08	The Clorox Company	Alkaline serine protease streptomyces griseus var. alkaliphus having enhanced stability against urea or guanidine
EP0995801A1 (de) *	1991-07-27	2000-04-26	Genencor International GmbH	Verfahren zur Verbesserung des Stabilität von Enzymen und stabilisierte Enzyme
US5275945A (en) *	1991-10-08	1994-01-04	Vista Chemical Company	Alkaline proteases stable in heavy-duty detergent liquids
WO1993008253A1 (en) *	1991-10-16	1993-04-29	Unilever N.V.	Aqueous enzymatic detergent compositions
US5371198A (en) *	1991-12-16	1994-12-06	Novo Nordisk A/S	Method for protection of proteolysis-susceptible protein during protein production in a fluid medium
US5623059A (en) *	1992-03-09	1997-04-22	Novo Nordisk A/S	Method for protection of proteolysis-susceptible protein during protein production in a fluid medium
EP0571014B1 (en) *	1992-05-18	2004-03-31	Genencor International, Inc.	Bacteria producing alkaline proteases, and production of these alkaline proteases
JP4028592B2 (ja) *	1992-07-17	2007-12-26	ジェネンコーインターナショナルインコーポレイテッド	高アルカリ性セリンプロテアーゼ
JPH0763377B2 (ja) *	1992-09-03	1995-07-12	大阪府	耐熱アルカリプロテアーゼ遺伝子、組換え体プラスミドｐＡＢＴ１７、枯草菌プラスミドベクターｐＡＢＴｔｓ１４およびその枯草菌プラスミドベクターｐＡＢＴｔｓ１４の形質転換体
DE4231726A1 (de) *	1992-09-23	1994-03-24	Cognis Bio Umwelt	Mutierte subtilisinartige Serinproteasen
GB9220669D0 (en) *	1992-09-30	1992-11-11	Unilever Plc	Detergent composition
US6440717B1 (en)	1993-09-15	2002-08-27	The Procter & Gamble Company	BPN′ variants having decreased adsorption and increased hydrolysis
US6436690B1 (en)	1993-09-15	2002-08-20	The Procter & Gamble Company	BPN′ variants having decreased adsorption and increased hydrolysis wherein one or more loop regions are substituted
ES2287931T3 (es) *	1993-10-14	2007-12-16	THE PROCTER & GAMBLE COMPANY	Composiciones limpiadoras que contienen proteasa.
AU1253695A (en) *	1993-10-14	1995-05-04	Procter & Gamble Company, The	Bleaching compositions comprising protease enzymes
MA23346A1 (fr)	1993-10-14	1995-04-01	Genencor Int	Variantes de la subtilisine
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US6455295B1 (en)	1995-03-08	2002-09-24	The Procter & Gamble Company	Subtilisin Carlsberg variants having decreased adsorption and increased hydrolysis
US6475765B1 (en)	1995-03-09	2002-11-05	Procter & Gamble Company	Subtilisin DY variants having decreased adsorption and increased hydrolysis
IL117350A0 (en)	1995-03-09	1996-07-23	Procter & Gamble	Proteinase k variants having decreased adsorption and increased hydrolysis
US6682924B1 (en) *	1995-05-05	2004-01-27	Novozymes A/S	Protease variants and compositions
JP3715320B2 (ja) *	1995-05-05	2005-11-09	ノボザイムスアクティーゼルスカブ	プロテアーゼ変異体及び組成物
US20120165241A1 (en) *	1995-05-05	2012-06-28	Unilever Plc	Subtilase Variants
US5837517A (en) *	1995-05-05	1998-11-17	Novo Nordisk A/S	Protease variants and compositions
US6936289B2 (en)	1995-06-07	2005-08-30	Danisco A/S	Method of improving the properties of a flour dough, a flour dough improving composition and improved food products
EP0948610B1 (en)	1996-11-04	2011-05-25	Novozymes A/S	Subtilase variants and compositions
BR9712878A (pt) *	1996-11-04	2000-02-01	Novo Nordisk As	Variante de enzima subtilase, processos para a identificação de uma variante de protease apresentando estabilidade autoproteolìtica e paraq a produção de uma enzima subtilase mutante e de uma variante de subtilase, sequência de dna, vetor, célula hospedeira microbiana, composição e uso de uma variante de subtilase.
US6077662A (en) *	1996-11-27	2000-06-20	Emory University	Virus-like particles, methods and immunogenic compositions
ATE280221T1 (de) *	1997-04-09	2004-11-15	Danisco	Verwendung von lipase zur verbesserung von teigen und backwaren
US6140475A (en)	1997-04-11	2000-10-31	Altus Biologics Inc.	Controlled dissolution crosslinked protein crystals
JP5095884B2 (ja)	1997-08-29	2012-12-12	ノボザイムスアクティーゼルスカブ	プロテアーゼ変異体及び組成物
JP2001514846A (ja)	1997-08-29	2001-09-18	ノボノルディスクアクティーゼルスカブ	プロテアーゼ変異体及び組成物
EP0913458B1 (en) *	1997-10-22	2004-06-16	The Procter & Gamble Company	Liquid hard-surface cleaning compositions
AR015977A1 (es) *	1997-10-23	2001-05-30	Genencor Int	Variantes de proteasa multiplemente substituida con carga neta alterada para su empleo en detergentes
ES2368718T3 (es)	1997-10-23	2011-11-21	Danisco Us Inc.	Variantes de subtilisina con múltiples sustituciones.
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US6835550B1 (en)	1998-04-15	2004-12-28	Genencor International, Inc.	Mutant proteins having lower allergenic response in humans and methods for constructing, identifying and producing such proteins
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US6376450B1 (en)	1998-10-23	2002-04-23	Chanchal Kumar Ghosh	Cleaning compositions containing multiply-substituted protease variants
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EP2287298A1 (en)	1998-11-27	2011-02-23	Novozymes A/S	Lipolytic enzyme variants
JP2002531130A (ja)	1998-12-08	2002-09-24	チルドレンズホスピタルアンドレジオナルメディカルセンター	ＥｓｃｈｅｒｉｃｈｉａｃｏｌｉＯ１５７：Ｈ７と他の株とを識別する多形遺伝子座
EP1803817B1 (en)	1998-12-18	2011-04-06	Novozymes A/S	Subtilase enzymes of the I-S1 and I-S2 sub-groups having an additional amino acid residue in an active site loop region
ATE422538T1 (de)	1999-03-31	2009-02-15	Novozymes As	Polypeptide mit alkaliner alpha-amylase-aktivität und für diese kodierende nukleinsäuren
ES2532606T3 (es)	1999-03-31	2015-03-30	Novozymes A/S	Polipéptidos con actividad de alfa-amilasa alcalina y ácidos nucleicos que los codifican
KR20000065867A (ko)	1999-04-09	2000-11-15	손경식	세탁세제용 알칼리성 단백질 분해효소 브이에이피케이, 이를 코딩하는 유전자, 재조합 발현벡터 및 형질전환된 균주
ATE402996T1 (de)	1999-05-20	2008-08-15	Novozymes As	Subtilase-enzyme der i-s1 und i-s2 untergruppen mit wenigstens einem zusätzlichen aminosäurerest zwischen positionen 125 und 126
EP1183342B2 (en) †	1999-05-20	2012-06-13	Novozymes A/S	Subtilase enzymes of the i-s1 and i-s2 sub-groups having at least one additional amino acid residue between positions 128 and 129
EP1183341B2 (en)	1999-05-20	2012-05-02	Novozymes A/S	Subtilase enzymes of the i-s1 and i-s2 sub-groups having at least one additional amino acid residue between positions 127 and 128
AU4392500A (en)	1999-05-20	2000-12-12	Novozymes A/S	Subtilase enzymes of the i-s1 and i-s2 sub-groups having at least one additionalamino acid residue between positions 132 and 133
ATE408678T1 (de)	1999-05-20	2008-10-15	Novozymes As	Subtilase enzyme der i-s1 und i-s2 untergruppen mit mindestens einer zusätzlichen aminosäure zwischen position 129 und 130
AU4392800A (en)	1999-05-20	2000-12-12	Novozymes A/S	Subtilase enzymes of the i-s1 and i-s2 sub-groups having at least one additionalamino acid residue between positions 126 and 127
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JP4198987B2 (ja)	2000-10-13	2008-12-17	ノボザイムスアクティーゼルスカブ	サブチラーゼ変異体
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WO2002077187A2 (en)	2001-03-23	2002-10-03	Genencor International, Inc.	Proteins producing an altered immunogenic response and methods of making and using the same
DE10121463A1 (de) *	2001-05-02	2003-02-27	Henkel Kgaa	Neue Alkalische Protease-Varianten und Wasch- und Reinigungsmittel enthaltend diese neuen Alkalischen Protease-Varianten
EP2159279A3 (en)	2001-05-15	2010-05-12	Novozymes A/S	Alpha-amylase variant with altered properties
CN100591212C (zh)	2001-05-18	2010-02-24	丹尼斯科有限公司	改善生面团和面包质量的方法
EP2295544B1 (en)	2001-06-26	2016-06-22	Novozymes A/S	Polypeptides having cellobiohydrolase I activity and polynucleotides encoding same
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US6799287B1 (en)	2000-05-01	2004-09-28	Hewlett-Packard Development Company, L.P.	Method and apparatus for verifying error correcting codes
US7109016B2 (en) *	2000-08-21	2006-09-19	Novozymes A/S	Subtilase enzymes
US6893855B2 (en) *	2000-10-13	2005-05-17	Novozymes A/S	Subtilase variants
DK200101090A (da) *	2001-07-12	2001-08-16	Novozymes As	Subtilase variants
US7888093B2 (en) *	2002-11-06	2011-02-15	Novozymes A/S	Subtilase variants
US20070161531A1 (en) *	2005-07-08	2007-07-12	Novozymes A/S	Subtilase variants

1988
- 1988-01-07 DK DK006488A patent/DK6488D0/da not_active Application Discontinuation
1989
- 1989-01-06 EP EP95107678A patent/EP0675196A3/en not_active Ceased
- 1989-01-06 JP JP1501511A patent/JPH0675504B2/ja not_active Expired - Fee Related
- 1989-01-06 AT AT89901711T patent/ATE136329T1/de not_active IP Right Cessation
- 1989-01-06 WO PCT/DK1989/000002 patent/WO1989006279A1/en not_active Ceased
- 1989-01-06 DE DE68926163T patent/DE68926163T2/de not_active Expired - Fee Related
- 1989-01-06 EP EP04025116A patent/EP1498481A1/en not_active Withdrawn
- 1989-01-06 EP EP05004172A patent/EP1538204A3/en not_active Withdrawn
- 1989-01-06 EP EP89901711A patent/EP0396608B1/en not_active Expired - Lifetime
1990
- 1990-07-04 DK DK199001612A patent/DK175697B1/da not_active IP Right Cessation
1994
- 1994-02-10 JP JP6016202A patent/JP2726799B2/ja not_active Expired - Lifetime
1995
- 1995-06-07 US US08/486,846 patent/US6506589B1/en not_active Expired - Lifetime
- 1995-06-07 US US08/486,415 patent/US5741694A/en not_active Expired - Lifetime
1996
- 1996-03-29 DK DK199600361A patent/DK176102B1/da not_active IP Right Cessation
1997
- 1997-10-01 JP JP9268984A patent/JPH10113179A/ja active Pending
2002
- 2002-11-27 US US10/306,089 patent/US6808913B2/en not_active Expired - Fee Related
- 2002-12-05 US US10/310,730 patent/US6835821B2/en not_active Expired - Fee Related
- 2002-12-06 US US10/313,853 patent/US6908991B2/en not_active Expired - Fee Related
2004
- 2004-07-21 US US10/896,177 patent/US20050003986A1/en not_active Abandoned

Also Published As

Publication number	Publication date
EP0396608A1 (en)	1990-11-14
EP0396608B1 (en)	1996-04-03
US5741694A (en)	1998-04-21
US20030148495A1 (en)	2003-08-07
US6506589B1 (en)	2003-01-14
US6808913B2 (en)	2004-10-26
DK161290D0 (da)	1990-07-04
US20050003986A1 (en)	2005-01-06
EP1538204A2 (en)	2005-06-08
JPH0675504B2 (ja)	1994-09-28
US6908991B2 (en)	2005-06-21
US20030175933A1 (en)	2003-09-18
EP1538204A3 (en)	2007-07-04
DE68926163D1 (de)	1996-05-09
JPH03503477A (ja)	1991-08-08
JP2726799B2 (ja)	1998-03-11
EP0675196A3 (en)	1995-11-22
DK161290A (da)	1990-09-07
DK175697B1 (da)	2005-01-24
EP0675196A2 (en)	1995-10-04
DK6488D0 (da)	1988-01-07
EP1498481A1 (en)	2005-01-19
US20030186378A1 (en)	2003-10-02
JPH06292577A (ja)	1994-10-21
JPH10113179A (ja)	1998-05-06
ATE136329T1 (de)	1996-04-15
US6835821B2 (en)	2004-12-28
DE68926163T2 (de)	1996-10-02
WO1989006279A1 (en)	1989-07-13
DK176102B1 (da)	2006-06-12

Legal Events

Date	Code	Title	Description
2009-01-26	PUP	Patent expired

Publication	Publication Date	Title
ATE136329T1 (de)	1996-04-15	Mutierte subtilisingene
ES2009238A6 (es)	1989-09-16	Metodo para producir proteinas de mycobacterium tuberculosis y peptidos antigenicos de las mismas.
ATE133681T1 (de)	1996-02-15	Mykobakterielle rekombinanten und peptide
GR3022124T3 (en)	1997-03-31	A yeast cell of the genus schwanniomyces
ES2154624T1 (es)	2001-04-16	Regulacion de la expresion de la quinolato fosforribosil transferasa.
ATE314086T1 (de)	2006-01-15	Arginin deiminase aus mycoplasma arthirtidis und sie enthaltende polymerkonjugate
DE69226636D1 (de)	1998-09-17	Stabilisierte enzyme
EP0205475A4 (en)	1990-06-27	RECOMBINANT METHOD FOR THE PRODUCTION OF SERINE PROTEASE INHIBITORS, AND DNA SEQUENCES THEREOF.
DE50010097D1 (de)	2005-05-25	Für das zwa1-Gen codierende Nukleotidsequenzen
HU0004168D0 (da)	2001-01-29
DE69535696D1 (de)	2008-03-13	Tripeptidyl-aminopeptidase
EP0828003A3 (en)	2003-01-15	Human serine protease
GB8626878D0 (en)	1986-12-10	Dna
DE3688324D1 (de)	1993-05-27	Dna-sequenzen, die fuer proteine mit der biologischen aktivitaet der husi-typi-inhibitoren codieren, gentechnologische verfahren zur herstellung dieser proteine und diese proteine enthaltende arzneimittel.
AU8258591A (en)	1992-02-27	Human mk gene and protein sequence
ATE282699T1 (de)	2004-12-15	Promotor aus ashbya gossypii
NO964997D0 (no)	1996-11-22	DNA som koder for Bacillus licheniformis PWD-1 keratinase
DE3586652D1 (de)	1992-10-22	Kloniertes streptomyces-beta-galaktosidase-promoter-fragment.
AU5727099A (en)	2000-04-10	A 2,6-beta-d-fructan hydrolase enzyme and processes for using the enzyme
KR930013111A (ko)	1993-07-21	바실러스의 파라-니트로벤질 에스테라제를 암호화하는 재조합 dna 화합물 및 발현벡터
DK470589A (da)	1990-03-30	Hidtil ukendte dna-sekvenser, der koder for biosyntetiske gen-produkter, samt rekombinant-dna-vektorer indeholdende saadanne sekvenser og vaertsceller transformeret med vektorerne
ATE78870T1 (de)	1992-08-15	Verfahren zur herstellung von neutraler protease.
DK251385D0 (da)	1985-06-04	Kultur af bacillus subtilis mutant og fremgangsmaade til fremstillingderaf samt fremgangsmaade til anvendelse deraf
ATE128484T1 (de)	1995-10-15	Serin-protease und serin-protease-gen.
ATE297993T1 (de)	2005-07-15	Cytochrom p450 gen