ECSP099427A - Barra de Tierra Segunda Generación 16 conexiones - Google Patents

Barra de Tierra Segunda Generación 16 conexiones

Info

Publication number
ECSP099427A
ECSP099427A EC2009009427A ECSP099427A ECSP099427A EC SP099427 A ECSP099427 A EC SP099427A EC 2009009427 A EC2009009427 A EC 2009009427A EC SP099427 A ECSP099427 A EC SP099427A EC SP099427 A ECSP099427 A EC SP099427A
Authority
EC
Ecuador
Prior art keywords
crystalline form
connections
ground bar
glk
oxy
Prior art date
Application number
EC2009009427A
Other languages
English (en)
Inventor
James Mccabe
Gary Peter Tomkinson
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39138920&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP099427(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of ECSP099427A publication Critical patent/ECSP099427A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Se describe en la descripción una nueva forma cristalina de 3-{[5-(azetidin-1-ilcarbonil)pirazin-2-il]oxi}-5-[(1-metiletil)oxi]-N-1H-pirazol-3-ilbenzamida. Este compuesto es un activador de la glucocinasa (GLK o GK) y resulta útil como agente farmacéutico en el tratamiento o la prevención de una enfermedad o afección médica mediada por GLK, que produce la reducción del umbral de glucosa para la secreción de insulina. También se describen procesos para la fabricación de la forma cristalina, composiciones farmacéuticas que comprenden la forma cristalina y el uso de la forma cristalina en tratamientos médicos.
EC2009009427A 2006-12-21 2009-06-15 Barra de Tierra Segunda Generación 16 conexiones ECSP099427A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US87125506P 2006-12-21 2006-12-21

Publications (1)

Publication Number Publication Date
ECSP099427A true ECSP099427A (es) 2009-07-31

Family

ID=39138920

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2009009427A ECSP099427A (es) 2006-12-21 2009-06-15 Barra de Tierra Segunda Generación 16 conexiones

Country Status (21)

Country Link
US (2) US20100094009A1 (es)
EP (1) EP2121666A1 (es)
JP (1) JP2010513445A (es)
KR (1) KR20090090390A (es)
CN (1) CN101595104A (es)
AR (1) AR064625A1 (es)
AU (1) AU2007336016A1 (es)
BR (1) BRPI0721143A2 (es)
CA (1) CA2671535A1 (es)
CL (1) CL2007003805A1 (es)
CO (1) CO6190522A2 (es)
EC (1) ECSP099427A (es)
MX (1) MX2009006729A (es)
NO (1) NO20092129L (es)
PE (1) PE20081396A1 (es)
RU (1) RU2009121756A (es)
SA (1) SA07280732B1 (es)
TW (1) TW200833339A (es)
UY (1) UY30822A1 (es)
WO (1) WO2008075073A1 (es)
ZA (1) ZA200904296B (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0102764D0 (sv) 2001-08-17 2001-08-17 Astrazeneca Ab Compounds
EP2048137A1 (en) * 2004-02-18 2009-04-15 AstraZeneca AB Benzamide derivatives and their use as glucokinase activating agents.
TW200600086A (en) * 2004-06-05 2006-01-01 Astrazeneca Ab Chemical compound
TW200714597A (en) * 2005-05-27 2007-04-16 Astrazeneca Ab Chemical compounds
KR20110084339A (ko) 2005-07-09 2011-07-21 아스트라제네카 아베 당뇨병 치료에 있어 ｇｌｋ 활성화제로서 사용하기 위한 헤테로아릴 벤즈아미드 유도체
TW200825060A (en) * 2006-10-26 2008-06-16 Astrazeneca Ab Chemical compounds
MX2011001333A (es) 2008-08-04 2011-03-15 Astrazeneca Ab Derivados de pirazolo [3, 4] pirimidin-4-ilo y sus usos para tratar la diabetes y obesidad.
GB0902434D0 (en) * 2009-02-13 2009-04-01 Astrazeneca Ab Chemical process
GB0902406D0 (en) * 2009-02-13 2009-04-01 Astrazeneca Ab Crystalline polymorphic form
AR076220A1 (es) 2009-04-09 2011-05-26 Astrazeneca Ab Derivados de pirazol [4,5 - e] pirimidina
WO2010116176A1 (en) * 2009-04-09 2010-10-14 Astrazeneca Ab Pyrazolo [4, 5-e] pyrimidine derivative and its use to treat diabetes and obesity
WO2011107494A1 (de) 2010-03-03 2011-09-09 Sanofi Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
EP2582709B1 (de) 2010-06-18 2018-01-24 Sanofi Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
US8530413B2 (en) 2010-06-21 2013-09-10 Sanofi Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201215388A (en) 2010-07-05 2012-04-16 Sanofi Sa (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
TW201215387A (en) 2010-07-05 2012-04-16 Sanofi Aventis Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
TW201221505A (en) 2010-07-05 2012-06-01 Sanofi Sa Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
WO2013037390A1 (en) 2011-09-12 2013-03-21 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
EP2760862B1 (en) 2011-09-27 2015-10-21 Sanofi 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
GB201714777D0 (en) 2017-09-14 2017-11-01 Univ London Queen Mary Agent

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Also Published As

Publication number Publication date
WO2008075073A1 (en) 2008-06-26
TW200833339A (en) 2008-08-16
JP2010513445A (ja) 2010-04-30
PE20081396A1 (es) 2008-12-05
NO20092129L (no) 2009-06-18
US20080153800A1 (en) 2008-06-26
CN101595104A (zh) 2009-12-02
BRPI0721143A2 (pt) 2014-03-11
CA2671535A1 (en) 2008-06-26
AU2007336016A1 (en) 2008-06-26
SA07280732B1 (ar) 2011-08-20
ZA200904296B (en) 2010-04-28
AR064625A1 (es) 2009-04-15
MX2009006729A (es) 2009-08-07
KR20090090390A (ko) 2009-08-25
US7696191B2 (en) 2010-04-13
UY30822A1 (es) 2008-07-31
US20100094009A1 (en) 2010-04-15
RU2009121756A (ru) 2011-01-27
EP2121666A1 (en) 2009-11-25
CO6190522A2 (es) 2010-08-19
CL2007003805A1 (es) 2008-08-01

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