MA26700A1 - FORMULATIONS PHARMACEUTIQUES D'INHIBITEURS DE PDE-5 DE GMPc à LIBERATION CONTROLEE, ET PROCEDE POUR LEUR PREPARATION. - Google Patents
FORMULATIONS PHARMACEUTIQUES D'INHIBITEURS DE PDE-5 DE GMPc à LIBERATION CONTROLEE, ET PROCEDE POUR LEUR PREPARATION.Info
- Publication number
- MA26700A1 MA26700A1 MA25820A MA25820A MA26700A1 MA 26700 A1 MA26700 A1 MA 26700A1 MA 25820 A MA25820 A MA 25820A MA 25820 A MA25820 A MA 25820A MA 26700 A1 MA26700 A1 MA 26700A1
- Authority
- MA
- Morocco
- Prior art keywords
- inhibitors
- preparation
- controlled release
- pharmaceutical formulations
- pde
- Prior art date
Links
- 229940123333 Phosphodiesterase 5 inhibitor Drugs 0.000 title abstract 3
- 239000002590 phosphodiesterase V inhibitor Substances 0.000 title abstract 3
- ZOOGRGPOEVQQDX-UUOKFMHZSA-N 3',5'-cyclic GMP Chemical compound C([C@H]1O2)OP(O)(=O)O[C@H]1[C@@H](O)[C@@H]2N1C(N=C(NC2=O)N)=C2N=C1 ZOOGRGPOEVQQDX-UUOKFMHZSA-N 0.000 title abstract 2
- 238000013270 controlled release Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 201000001880 Sexual dysfunction Diseases 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 238000012827 research and development Methods 0.000 abstract 1
- 231100000872 sexual dysfunction Toxicity 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Neurosurgery (AREA)
- Gynecology & Obstetrics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
DEPOSANT Société dite : PFIZER RESEARCH AND DEVELOPMENT COMPANY, N.V./S.A. REVENDICATION DE PRIORITES GB 23/10/1998 9823192.1 GB 27/10/1998 9826392.4 GB 16/11/1998 9825117.6 Voir en annexe le titre de l'invention et le texte de l'abrégé Formulations pharmaceutiques d'inhibiteurs de PDE-5 de GMPc à libération contrôlée,et procédé pour leur préparation L'invention concerne des formulations à libération contrôlée contenant un inhibiteur de PDE-5 de GMPc, pour l'administration orale. Elle concerne également un procédé pour leur préparation. Application : utilisation de ces formulations dans le traitement ou la prévention d'un dysfonctionnement sexuel.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9823192.1A GB9823192D0 (en) | 1998-10-23 | 1998-10-23 | Pharmaceutical formulations |
| GBGB9825117.6A GB9825117D0 (en) | 1998-11-16 | 1998-11-16 | Pharmaceutical formulations |
| GBGB9826392.4A GB9826392D0 (en) | 1998-11-27 | 1998-11-27 | Pharmaceutical formulations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA26700A1 true MA26700A1 (fr) | 2004-12-20 |
Family
ID=27269526
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA25820A MA26700A1 (fr) | 1998-10-23 | 1999-10-20 | FORMULATIONS PHARMACEUTIQUES D'INHIBITEURS DE PDE-5 DE GMPc à LIBERATION CONTROLEE, ET PROCEDE POUR LEUR PREPARATION. |
Country Status (44)
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TR200001338T2 (tr) * | 1997-11-12 | 2000-08-21 | Bayer Aktiengesellschaft | 2-Fenil-ikameli imidazotriazinonlar |
| CA2348871C (fr) | 1998-11-02 | 2009-04-14 | John G. Devane | Composition a liberation modifiee multiparticulaire |
| ATE526950T1 (de) | 1999-10-29 | 2011-10-15 | Euro Celtique Sa | Hydrocodon-formulierungen mit gesteuerter freisetzung |
| US10179130B2 (en) | 1999-10-29 | 2019-01-15 | Purdue Pharma L.P. | Controlled release hydrocodone formulations |
| ATE552013T1 (de) | 2000-09-06 | 2012-04-15 | Mitsubishi Tanabe Pharma Corp | Zubereitungen zur oralen anwendung |
| EP2283829A1 (fr) | 2000-10-30 | 2011-02-16 | Euro-Celtique S.A. | Formulations d'hydrocodone à liberation lente |
| EP1366760B1 (fr) * | 2001-02-15 | 2010-06-30 | Mitsubishi Tanabe Pharma Corporation | Comprimes a dissolution rapide dans la cavite buccale |
| US10675280B2 (en) | 2001-10-20 | 2020-06-09 | Sprout Pharmaceuticals, Inc. | Treating sexual desire disorders with flibanserin |
| UA78974C2 (en) | 2001-10-20 | 2007-05-10 | Boehringer Ingelheim Pharma | Use of flibanserin for treating disorders of sexual desire |
| ITMI20020515A1 (it) * | 2002-03-12 | 2003-09-12 | Jagotec Ag | Sistema per il rilasco controllato di uno o piu' principi attivi |
| GB0318824D0 (en) * | 2003-08-11 | 2003-09-10 | Glaxo Group Ltd | Novel composition |
| NZ551356A (en) | 2004-05-11 | 2009-09-25 | Emotional Brain Bv | Pharmaceutical formulations and uses thereof in the treatment of female sexual dysfunction |
| DE102004023069A1 (de) * | 2004-05-11 | 2005-12-08 | Bayer Healthcare Ag | Neue Darreichungsformen des PDE 5-Inhibitors Vardenafil |
| GB0421121D0 (en) * | 2004-09-22 | 2004-10-27 | Natrocell Technologies Ltd | Composite rodenticide |
| DE102005001989A1 (de) * | 2005-01-15 | 2006-07-20 | Bayer Healthcare Ag | Intravenöse Formulierungen von PDE-Inhibitoren |
| DE102005009241A1 (de) * | 2005-03-01 | 2006-09-07 | Bayer Healthcare Ag | Arzneiformen mit kontrollierter Bioverfügbarkeit |
| DE102005009240A1 (de) | 2005-03-01 | 2006-09-07 | Bayer Healthcare Ag | Arzneiformen mit verbesserten pharmakokinetischen Eigenschaften |
| WO2007000764A2 (fr) * | 2005-06-27 | 2007-01-04 | Daniel Drai | Compositions et methodes permettant d'ameliorer la fonction sexuelle |
| ES2646326T3 (es) | 2005-08-03 | 2017-12-13 | Sprout Pharmaceuticals, Inc. | Uso de flibanserina en el tratamiento de la obesidad |
| CA2623657A1 (fr) * | 2005-09-29 | 2007-04-12 | Bayer Healthcare Ag | Inhibiteurs pde et combinaisons de ceux-ci pour traiter des troubles urinaires |
| WO2007048803A1 (fr) | 2005-10-29 | 2007-05-03 | Boehringer Ingelheim International Gmbh | Derives de benzimidazolone utiles pour le traitement des troubles premenstruels et d'autres troubles sexuels chez la femme |
| EP1790343A1 (fr) * | 2005-11-11 | 2007-05-30 | Emotional Brain B.V. | Compositions pharmaceutiques et leur utilisation pour le traitement des dysfonctions sexuelles chez la femme |
| WO2008000760A1 (fr) | 2006-06-30 | 2008-01-03 | Boehringer Ingelheim International Gmbh | Flibansérine dans le traitement de l'incontinence urinaire et des maladies associées |
| BRPI0716439B8 (pt) | 2006-08-14 | 2021-05-25 | Boehringer Ingelheim Int | sistemas de liberação farmacêutico compreendendo flibanserina, processo para preparação e uso dos mesmos |
| BRPI0716436B8 (pt) | 2006-08-25 | 2021-05-25 | Boehringer Ingelheim Int | sistema de liberação controlada e método para fabricação do mesmo |
| EP1925307A1 (fr) * | 2006-11-03 | 2008-05-28 | Emotional Brain B.V. | Utilisation de 3-alpha-androstanediol pour le traitement des dysfonctions sexuelles |
| US20080226715A1 (en) * | 2007-03-16 | 2008-09-18 | Albert Cha | Therapeutic compositions and methods |
| EP2167057A1 (fr) * | 2007-06-13 | 2010-03-31 | Bayer HealthCare AG | Inhibiteurs de la phosphodiestérase (pde) destinés au traitement des troubles de l'audition |
| CL2008002693A1 (es) | 2007-09-12 | 2009-10-16 | Boehringer Ingelheim Int | Uso de flibanserina para el tratamiento de sintomas vasomotores seleccionados de sofocos, sudores nocturnos, cambios de estado de animo e irritabilidad |
| US20110033506A1 (en) * | 2008-02-08 | 2011-02-10 | Adel Penhasi | Combination dosage form of low-dose modafinil and low-dose sildenafil |
| EP2374460A4 (fr) * | 2008-12-12 | 2013-08-21 | Rhein Siegfried Sa De Cv | Composition de sildénafil à libération pulsée et son procédé de préparation |
| KR101004205B1 (ko) * | 2008-12-17 | 2010-12-24 | 동아제약주식회사 | 유데나필 함유 서방성 제제를 제조하기 위한 제어방출 조성물 |
| EA015250B9 (ru) * | 2010-11-19 | 2013-10-30 | Тева Фармасьютикал Индастриз, Лтд. | Таблетка силденафила, обеспечивающая модифицированную фармакокинетику, и способ ее изготовления |
| PH12013502325A1 (en) | 2011-05-13 | 2014-02-10 | Eb Ip Hybritabs B V | Drug delivery system |
| WO2013016144A1 (fr) * | 2011-07-22 | 2013-01-31 | Pom Wonderful, Llc | Compositions comprenant des polyphénols de grenade en combinaison avec des composés de traitement de la dysérection, et procédé de traitement de la dysérection à l'aide de celle-ci |
| WO2017168174A1 (fr) * | 2016-04-02 | 2017-10-05 | N4 Pharma Uk Limited | Nouvelles formes pharmaceutiques du sildénafil |
| CN113995727B (zh) * | 2021-11-08 | 2023-04-07 | 山东鲁抗医药股份有限公司 | 一种5型磷酸二酯酶抑制剂片剂及其制备方法 |
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| US3952741A (en) | 1975-01-09 | 1976-04-27 | Bend Research Inc. | Controlled release delivery system by an osmotic bursting mechanism |
| JPS54119021A (en) * | 1978-03-06 | 1979-09-14 | Nippon Kayaku Co Ltd | Carcinostatic agent |
| CH648754A5 (en) * | 1979-08-16 | 1985-04-15 | Ciba Geigy Ag | Pharmaceutical slow release tablet |
| JPS5748908A (en) * | 1980-09-08 | 1982-03-20 | Kyorin Pharmaceut Co Ltd | Prolonged release type nicomol pharmaceutical |
| FR2624732B1 (fr) | 1987-12-21 | 1991-02-15 | Synthelabo | Formulation pharmaceutique a liberation prolongee |
| MC2025A1 (fr) * | 1988-04-20 | 1990-04-25 | Asta Pharma Ag | Medicament contenant de l'azelastine et capable de liberer celle-ci de facon controlee |
| IT1229856B (it) * | 1989-04-20 | 1991-09-13 | Recordati Chem Pharm | Compresse a rilascio controllato contenenti flavossato. |
| US5474784A (en) | 1990-03-02 | 1995-12-12 | British Technology Group Limited | Dispensing device |
| GB9013750D0 (en) | 1990-06-20 | 1990-08-08 | Pfizer Ltd | Therapeutic agents |
| GB9114760D0 (en) | 1991-07-09 | 1991-08-28 | Pfizer Ltd | Therapeutic agents |
| PT621032E (pt) * | 1993-04-23 | 2001-01-31 | Novartis Ag | Dispositivo de distribuicao de libertacao controlada de farmaco |
| GB9301192D0 (en) * | 1993-06-09 | 1993-06-09 | Trott Francis W | Flower shaped mechanised table |
| US5464633A (en) | 1994-05-24 | 1995-11-07 | Jagotec Ag | Pharmaceutical tablets releasing the active substance after a definite period of time |
| US5656629A (en) * | 1995-03-10 | 1997-08-12 | Sanofi Winthrop, Inc. | 6-substituted pyrazolo (3,4-d)pyrimidin-4-ones and compositions and methods of use thereof |
| US5888534A (en) | 1995-06-13 | 1999-03-30 | Pentech Pharmaceuticals, Inc. | Controlled release of drugs delivered by sublingual or buccal administration |
| GB9514464D0 (en) * | 1995-07-14 | 1995-09-13 | Glaxo Lab Sa | Medicaments |
| GB9523752D0 (en) * | 1995-11-21 | 1996-01-24 | Pfizer Ltd | Pharmaceutical formulations |
| JPH1067657A (ja) * | 1996-06-18 | 1998-03-10 | Otsuka Pharmaceut Co Ltd | マルチプルユニット型持続性製剤 |
| WO1997048382A2 (fr) * | 1996-06-18 | 1997-12-24 | Otsuka Pharmaceutical Co., Ltd. | Preparation medicamenteuse d'action prolongee, de type a plusieurs unites |
| HUP0002744A3 (en) * | 1997-01-06 | 2001-01-29 | Pfizer | Rapidly releasing and taste-masking pharmaceutical dosage form |
| US6046177A (en) * | 1997-05-05 | 2000-04-04 | Cydex, Inc. | Sulfoalkyl ether cyclodextrin based controlled release solid pharmaceutical formulations |
| US5874418A (en) * | 1997-05-05 | 1999-02-23 | Cydex, Inc. | Sulfoalkyl ether cyclodextrin based solid pharmaceutical formulations and their use |
| US6403597B1 (en) * | 1997-10-28 | 2002-06-11 | Vivus, Inc. | Administration of phosphodiesterase inhibitors for the treatment of premature ejaculation |
| US6277884B1 (en) * | 1998-06-01 | 2001-08-21 | Nitromed, Inc. | Treatment of sexual dysfunction with N-hydroxyguanidine compounds |
| DK1109814T3 (da) * | 1998-09-04 | 2004-08-02 | Ortho Mcneil Pharm Inc | 5-Heterocyclylpyrazolo[4,3-d]pyrimidin-7-oner til behandling af mandlig erektil dysfunktion |
-
1999
- 1999-04-10 UA UA2001042718A patent/UA67802C2/uk unknown
- 1999-10-01 TW TW088116973A patent/TW577756B/zh not_active IP Right Cessation
- 1999-10-04 AT AT99946377T patent/ATE340562T1/de not_active IP Right Cessation
- 1999-10-04 AU AU58787/99A patent/AU756509B2/en not_active Ceased
- 1999-10-04 CA CA002348086A patent/CA2348086C/fr not_active Expired - Fee Related
- 1999-10-04 IL IL141764A patent/IL141764A/en unknown
- 1999-10-04 PL PL99347476A patent/PL195789B1/pl not_active IP Right Cessation
- 1999-10-04 EA EA200100298A patent/EA004068B1/ru not_active IP Right Cessation
- 1999-10-04 HU HU0104318A patent/HUP0104318A3/hu unknown
- 1999-10-04 DK DK99946377T patent/DK1123088T3/da active
- 1999-10-04 TR TR2001/01103T patent/TR200101103T2/xx unknown
- 1999-10-04 BR BR9914718-1A patent/BR9914718A/pt not_active Application Discontinuation
- 1999-10-04 HK HK02103588.0A patent/HK1041818A1/zh unknown
- 1999-10-04 CZ CZ20011427A patent/CZ20011427A3/cs unknown
- 1999-10-04 SK SK519-2001A patent/SK286473B6/sk unknown
- 1999-10-04 EP EP99946377A patent/EP1123088B1/fr not_active Expired - Lifetime
- 1999-10-04 CN CN99812510A patent/CN1324233A/zh active Pending
- 1999-10-04 AP APAP/P/2001/002125A patent/AP2001002125A0/en unknown
- 1999-10-04 JP JP2000577993A patent/JP2002528408A/ja active Pending
- 1999-10-04 KR KR1020017005042A patent/KR20010075659A/ko not_active Ceased
- 1999-10-04 HR HR20010285A patent/HRP20010285A2/xx not_active Application Discontinuation
- 1999-10-04 OA OA1200100093A patent/OA11664A/en unknown
- 1999-10-04 NZ NZ510275A patent/NZ510275A/en unknown
- 1999-10-04 MX MXPA01004011A patent/MXPA01004011A/es active IP Right Grant
- 1999-10-04 ES ES99946377T patent/ES2272082T3/es not_active Expired - Lifetime
- 1999-10-04 EE EEP200100235A patent/EE200100235A/xx unknown
- 1999-10-04 WO PCT/IB1999/001619 patent/WO2000024383A1/fr not_active Ceased
- 1999-10-04 DE DE69933383T patent/DE69933383T2/de not_active Expired - Fee Related
- 1999-10-04 ID IDW20010891A patent/ID28232A/id unknown
- 1999-10-04 PT PT99946377T patent/PT1123088E/pt unknown
- 1999-10-18 PA PA19998484301A patent/PA8484301A1/es unknown
- 1999-10-20 DZ DZ990223A patent/DZ2923A1/fr active
- 1999-10-20 MA MA25820A patent/MA26700A1/fr unknown
- 1999-10-20 MY MYPI99004535A patent/MY130727A/en unknown
- 1999-10-21 PE PE1999001062A patent/PE20001286A1/es not_active Application Discontinuation
- 1999-10-22 CO CO99066970A patent/CO5160262A1/es unknown
- 1999-10-22 GT GT199900184A patent/GT199900184A/es unknown
- 1999-10-22 US US09/425,622 patent/US6964780B1/en not_active Expired - Fee Related
- 1999-10-22 UY UY25765A patent/UY25765A1/es not_active Application Discontinuation
-
2001
- 2001-02-27 IS IS5865A patent/IS5865A/is unknown
- 2001-03-14 CR CR6326A patent/CR6326A/es not_active Application Discontinuation
- 2001-04-19 NO NO20011933A patent/NO20011933L/no not_active Application Discontinuation
- 2001-04-24 BG BG105465A patent/BG65323B1/bg unknown
-
2006
- 2006-11-13 CY CY20061101644T patent/CY1106239T1/el unknown
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