MA29543B1 - Procedes pour traiter un cancer pharmacoresistant - Google Patents

Procedes pour traiter un cancer pharmacoresistant

Info

Publication number
MA29543B1
MA29543B1 MA30468A MA30468A MA29543B1 MA 29543 B1 MA29543 B1 MA 29543B1 MA 30468 A MA30468 A MA 30468A MA 30468 A MA30468 A MA 30468A MA 29543 B1 MA29543 B1 MA 29543B1
Authority
MA
Morocco
Prior art keywords
resistant cancer
methods
compound
treating drug
salt
Prior art date
Application number
MA30468A
Other languages
English (en)
Inventor
Glenn C Michelson
Vivien W Chan
Carla C Heise
Marion Wiesmann
Timothy D Dawes
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MA29543B1 publication Critical patent/MA29543B1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4425—Pyridinium derivatives, e.g. pralidoxime, pyridostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

LA PRÉSENTE INVENTION CONCERNE UN PROCÉDÉ POUR TRAITER UN CANCER PHARMACORÉSISTANT, QUI CONSISTE À ADMINISTRER À UN PATIENT QUI LE NÉCESSITE UN COMPOSÉ DE FORMULE (I), UN TAUTOMÈRE DE CE COMPOSÉ, UN SEL DE CE COMPOSÉ, UN SEL DUDIT TAUTOMÈRE OU UN MÉLANGE DE CEUX-CI OU UNE COMPOSITION PHARMACEUTIQUE COMPRENANT LEDIT COMPOSÉ, LEDIT TAUTOMÈRE, LEDIT SEL DU COMPOSÉ, LEDIT SEL DU TAUTOMÈRE OU LEDIT MÉLANGE. LE PATIENT EST UN PATIENT ATTEINT D'UN CANCER PHARMACORÉSISTANT ET LE COMPOSÉ DE FORMULE (I) EST TEL QUE DÉFINI DANS LA DEMANDE.
MA30468A 2005-05-13 2007-12-10 Procedes pour traiter un cancer pharmacoresistant MA29543B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US68072205P 2005-05-13 2005-05-13

Publications (1)

Publication Number Publication Date
MA29543B1 true MA29543B1 (fr) 2008-06-02

Family

ID=37431829

Family Applications (1)

Application Number Title Priority Date Filing Date
MA30468A MA29543B1 (fr) 2005-05-13 2007-12-10 Procedes pour traiter un cancer pharmacoresistant

Country Status (22)

Country Link
US (1) US8299081B2 (fr)
EP (1) EP1885187B1 (fr)
JP (2) JP5344910B2 (fr)
KR (1) KR101319122B1 (fr)
CN (1) CN101222850B (fr)
AU (1) AU2006247803B2 (fr)
BR (1) BRPI0610360A2 (fr)
CA (1) CA2608171C (fr)
DK (1) DK1885187T3 (fr)
ES (1) ES2440799T3 (fr)
IL (1) IL187327A (fr)
MA (1) MA29543B1 (fr)
MX (1) MX2007014206A (fr)
NO (1) NO20076425L (fr)
NZ (1) NZ564144A (fr)
PL (1) PL1885187T3 (fr)
PT (1) PT1885187E (fr)
RU (1) RU2426539C2 (fr)
SI (1) SI1885187T1 (fr)
TN (1) TNSN07419A1 (fr)
WO (1) WO2006124413A2 (fr)
ZA (1) ZA200709620B (fr)

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CN101423513B (zh) * 2007-10-29 2013-03-27 中国医学科学院药物研究所 胺基嘧啶衍生物、及其制法和药物组合物与用途
EP2149372B1 (fr) 2008-07-31 2014-04-02 Universität Ulm Utilisation d'opioïdes du groupe de la méthadone pour le traitement des patients atteints d'un cancer résistant
US9095592B2 (en) * 2008-11-07 2015-08-04 The Research Foundation For The State University Of New York Bruton's tyrosine kinase as anti-cancer drug target
US9519613B2 (en) * 2009-02-02 2016-12-13 Asurion, Llc Method for integrating applications in an electronic address book
TWI410418B (zh) 2009-04-29 2013-10-01 Ind Tech Res Inst 氮雜薁化合物、藥學組合物與抑制一細胞中蛋白質激酶之活性的方法
CA2795089A1 (fr) * 2010-04-16 2011-10-20 Novartis Ag Combinaison de composes organiques
EP2709729A1 (fr) * 2011-05-19 2014-03-26 Novartis AG 4-amino-5-fluoro-3-[6-(4-méthylpipérazin-1-yl)-1h-benzimidazol-2-yl]-1h-quinoléin-2-one destinée à être utilisée dans le traitement du carcinome adénoïde kystique
WO2013063003A1 (fr) 2011-10-28 2013-05-02 Novartis Ag Méthode de traitement des tumeurs stromales gastro-intestinales
KR20140117457A (ko) * 2012-01-31 2014-10-07 노파르티스 아게 Rtk 억제제와 항에스트로겐의 조합물 및 암의 치료를 위한 그의 용도
IN2014DN10801A (fr) 2012-07-11 2015-09-04 Novartis Ag
WO2014058785A1 (fr) 2012-10-10 2014-04-17 Novartis Ag Polythérapie
RU2547999C1 (ru) * 2013-10-28 2015-04-10 Государственное бюджетное учреждение здравоохранения Московской области "Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского" (ГБУЗ МО МОНИКИ им. М.Ф. Владимирского) Способ лечения аденогенного местно-распространенного рака нижнеампулярного отдела прямой кишки
WO2016123054A2 (fr) * 2015-01-26 2016-08-04 The University Of North Carolina At Chapel Hill Combinaisons de médicaments à base de kinase et leurs procédés d'utilisation
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Also Published As

Publication number Publication date
PL1885187T3 (pl) 2014-03-31
BRPI0610360A2 (pt) 2010-06-15
AU2006247803A1 (en) 2006-11-23
DK1885187T3 (da) 2013-12-09
NZ564144A (en) 2009-11-27
CN101222850B (zh) 2012-10-03
WO2006124413A2 (fr) 2006-11-23
ZA200709620B (en) 2008-10-29
WO2006124413A3 (fr) 2007-06-07
EP1885187B1 (fr) 2013-09-25
IL187327A (en) 2015-05-31
SI1885187T1 (sl) 2013-12-31
TNSN07419A1 (en) 2009-03-17
CN101222850A (zh) 2008-07-16
JP5344910B2 (ja) 2013-11-20
HK1110477A1 (en) 2008-07-18
US8299081B2 (en) 2012-10-30
JP2008540543A (ja) 2008-11-20
RU2007145932A (ru) 2009-06-20
CA2608171A1 (fr) 2006-11-23
KR20080033902A (ko) 2008-04-17
AU2006247803B2 (en) 2011-12-22
IL187327A0 (en) 2008-04-13
MX2007014206A (es) 2008-02-07
ES2440799T3 (es) 2014-01-30
KR101319122B1 (ko) 2013-10-23
EP1885187A2 (fr) 2008-02-13
US20090215793A1 (en) 2009-08-27
NO20076425L (no) 2008-01-30
EP1885187A4 (fr) 2009-05-13
JP2013173787A (ja) 2013-09-05
CA2608171C (fr) 2014-02-04
RU2426539C2 (ru) 2011-08-20
PT1885187E (pt) 2013-12-16

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