MA29567B1 - (5z)-5-(6-quinoxalinylmethylidene)-2-[(2,6-dichlorophenyl) amino]-1,3-thiazol-4(5h)-one - Google Patents

(5z)-5-(6-quinoxalinylmethylidene)-2-[(2,6-dichlorophenyl) amino]-1,3-thiazol-4(5h)-one

Info

Publication number
MA29567B1
MA29567B1 MA30514A MA30514A MA29567B1 MA 29567 B1 MA29567 B1 MA 29567B1 MA 30514 A MA30514 A MA 30514A MA 30514 A MA30514 A MA 30514A MA 29567 B1 MA29567 B1 MA 29567B1
Authority
MA
Morocco
Prior art keywords
quinoxalinylmethylidene
thiazol
dichlorophenyl
amino
compound
Prior art date
Application number
MA30514A
Other languages
English (en)
Inventor
Kevin J Duffy
Duke M Fitch
Beth A Norton
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of MA29567B1 publication Critical patent/MA29567B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

EST INVENTÉ LE COMPOSÉ (5Z)-5-(6-QUINOXALINYLMÉTHYLIDÈNE)-2-[(2,6-DICHLOROPHÉNYL)AMINO]-1,3-THIAZOL-4(5H)-ONE, ET/OU SES SELS, HYDRATES, SOLVATES ET PROMÉDICAMENTS PHARMACEUTIQUEMENT ACCEPTABLES. L¿INVENTION CONCERNE ÉGALEMENT DES COMPOSITIONS PHARMACEUTIQUES CONTENANT CE COMPOSÉ, DES MÉTHODES DE PRÉPARATION DE CE COMPOSÉ AINSI QUE DE SES SELS, HYDRATES, SOLVATES ET PROMÉDICAMENTS PHARMACEUTIQUEMENT ACCEPTABLES. L¿INVENTION CONCERNE ÉGALEMENT DES PROCÉDÉS D¿UTILISATION DE CE COMPOSÉ EN TANT QU¿INHIBITEUR DE PROTÉINES HYAK3.
MA30514A 2005-06-08 2007-12-26 (5z)-5-(6-quinoxalinylmethylidene)-2-[(2,6-dichlorophenyl) amino]-1,3-thiazol-4(5h)-one MA29567B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US68867105P 2005-06-08 2005-06-08

Publications (1)

Publication Number Publication Date
MA29567B1 true MA29567B1 (fr) 2008-06-02

Family

ID=37532819

Family Applications (1)

Application Number Title Priority Date Filing Date
MA30514A MA29567B1 (fr) 2005-06-08 2007-12-26 (5z)-5-(6-quinoxalinylmethylidene)-2-[(2,6-dichlorophenyl) amino]-1,3-thiazol-4(5h)-one

Country Status (21)

Country Link
US (1) US7674792B2 (fr)
EP (1) EP1888531A4 (fr)
JP (1) JP2008543770A (fr)
KR (1) KR20080014017A (fr)
CN (1) CN101193863A (fr)
AP (1) AP2007004241A0 (fr)
AR (1) AR054059A1 (fr)
AU (1) AU2006258032A1 (fr)
BR (1) BRPI0611096A2 (fr)
CA (1) CA2611480A1 (fr)
EA (1) EA200702457A1 (fr)
IL (1) IL187423A0 (fr)
MA (1) MA29567B1 (fr)
MX (1) MX2007015572A (fr)
NO (1) NO20080130L (fr)
NZ (1) NZ563421A (fr)
PE (1) PE20070083A1 (fr)
TW (1) TW200716580A (fr)
UY (1) UY29581A1 (fr)
WO (1) WO2006135712A2 (fr)
ZA (1) ZA200709813B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080194466A1 (en) * 2005-06-08 2008-08-14 Duffy Kevin J (5Z)-5-(6-Quinoxalinylmethylidene)-2-[(2,4,6-Trichlorophenyl)Amino]-1,3-Thiazol-4(5H)-One
US20100286041A1 (en) * 2007-03-22 2010-11-11 Smithkline Beecham Corporation (5z)-5-(6-quinoxalinylmethylidene)-2-[(2,6-dichlorophenyl)amino]-1,3-thiazol-4(5h)-one
US20100184774A1 (en) * 2007-06-01 2010-07-22 Duffy Kevin J Methods of treatment

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Also Published As

Publication number Publication date
MX2007015572A (es) 2008-02-25
WO2006135712A2 (fr) 2006-12-21
UY29581A1 (es) 2006-11-30
NO20080130L (no) 2008-01-08
IL187423A0 (en) 2008-02-09
ZA200709813B (en) 2008-09-25
US7674792B2 (en) 2010-03-09
AU2006258032A1 (en) 2006-12-21
EP1888531A4 (fr) 2009-06-17
PE20070083A1 (es) 2007-01-27
TW200716580A (en) 2007-05-01
KR20080014017A (ko) 2008-02-13
AR054059A1 (es) 2007-05-30
CA2611480A1 (fr) 2006-12-21
AP2007004241A0 (en) 2007-12-31
EP1888531A2 (fr) 2008-02-20
EA200702457A1 (ru) 2008-04-28
US20070179144A1 (en) 2007-08-02
BRPI0611096A2 (pt) 2010-12-21
NZ563421A (en) 2010-07-30
CN101193863A (zh) 2008-06-04
WO2006135712A3 (fr) 2007-06-28
JP2008543770A (ja) 2008-12-04

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