MEP2208A - Postupak za pripremanje citaloprama - Google Patents

Postupak za pripremanje citaloprama

Info

Publication number
MEP2208A
MEP2208A MEP-22/08A MEP2208A MEP2208A ME P2208 A MEP2208 A ME P2208A ME P2208 A MEP2208 A ME P2208A ME P2208 A MEP2208 A ME P2208A
Authority
ME
Montenegro
Prior art keywords
citalopram
compound
formula
preparation
gringnard
Prior art date
Application number
MEP-22/08A
Other languages
Bosnian (bs)
English (en)
Inventor
Hans Petersen
Haleh Ahmadian
Robert J M Dancer
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of MEP2208A publication Critical patent/MEP2208A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Addiction (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
MEP-22/08A 2000-08-18 2001-08-14 Postupak za pripremanje citaloprama MEP2208A (xx)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200001231 2000-08-18
PCT/DK2001/000542 WO2002016342A1 (en) 2000-08-18 2001-08-14 Method for the preparation of citalopram

Publications (1)

Publication Number Publication Date
MEP2208A true MEP2208A (xx) 2010-02-10

Family

ID=8159660

Family Applications (2)

Application Number Title Priority Date Filing Date
MEP-22/08A MEP2208A (xx) 2000-08-18 2001-08-14 Postupak za pripremanje citaloprama
MEP-23/08A MEP2308A (xx) 2000-08-18 2001-08-14 Postupak za pripremanje citaloprama

Family Applications After (1)

Application Number Title Priority Date Filing Date
MEP-23/08A MEP2308A (xx) 2000-08-18 2001-08-14 Postupak za pripremanje citaloprama

Country Status (41)

Country Link
US (2) US6426422B1 (is)
EP (2) EP1309581B1 (is)
JP (2) JP2004506729A (is)
KR (2) KR100887206B1 (is)
CN (3) CN1222517C (is)
AR (3) AR029598A1 (is)
AT (4) ATE281448T1 (is)
AU (6) AU7960901A (is)
BE (2) BE1013443A6 (is)
BG (2) BG65964B1 (is)
CA (2) CA2354877C (is)
CH (2) CH691969A5 (is)
CL (2) CL2008002412A1 (is)
CZ (2) CZ294746B6 (is)
DE (4) DE60106932T2 (is)
DK (4) DK200101219A (is)
EA (2) EA005811B1 (is)
ES (4) ES2228920T3 (is)
FI (2) FI20011622L (is)
FR (2) FR2813077B1 (is)
GB (2) GB2362647B (is)
GR (1) GR1004074B (is)
HK (2) HK1044538B (is)
HR (2) HRP20030065A2 (is)
HU (2) HUP0103291A3 (is)
IE (2) IES20010760A2 (is)
IL (2) IL144816A (is)
IS (2) IS2121B (is)
ME (2) MEP2208A (is)
MX (2) MXPA03000913A (is)
NL (2) NL1018776C1 (is)
NO (2) NO326570B1 (is)
NZ (2) NZ523877A (is)
PL (2) PL359969A1 (is)
PT (2) PT1309582E (is)
RS (2) RS50258B (is)
SI (2) SI1309582T1 (is)
SK (2) SK287236B6 (is)
UA (2) UA71676C2 (is)
WO (2) WO2002016341A1 (is)
ZA (1) ZA200106683B (is)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
DK1173431T4 (da) 1999-04-14 2010-01-04 Lundbeck & Co As H Fremgangsmåde til fremstilling af citalopram
ITMI991581A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
HRP20020344B1 (hr) 1999-10-25 2010-10-31 H. Lundbeck A/S Način priprave citaloprama
AR026063A1 (es) 1999-11-01 2002-12-26 Lundbeck & Co As H Metodo para la preparacion de 5-carboxiftalida.
HUP0203635A3 (en) 1999-12-28 2005-02-28 Lundbeck & Co As H Method for the preparation of citalopram
PT1246813E (pt) 1999-12-30 2004-02-27 Lundbeck & Co As H Metodo para a preparacao de citalopram
CN1195749C (zh) * 2000-01-14 2005-04-06 H.隆德贝克有限公司 制备5－氰基2－苯并[c]呋喃酮的方法
NL1017417C1 (nl) 2000-03-03 2001-03-16 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
KR20020080481A (ko) 2000-03-13 2002-10-23 하. 룬트벡 아크티에 셀스카브 시탈로프람의 제조 방법
CN1427835A (zh) * 2000-03-13 2003-07-02 H·隆德贝克有限公司 5－取代的1－(4－氟苯基)－1,3－二氢异苯并呋喃的分步烷基化
IES20010206A2 (en) 2000-03-13 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
TR200202155T2 (tr) 2000-03-14 2002-12-23 H. Lundbeck A/S Sitalopramin preparasyon metodu
DE10190485T1 (de) * 2000-03-16 2002-03-21 Lundbeck & Co As H Verfahren zur Herstellung von 5-Cyano-1-(4-fluorphenyl)-1,3-dihydroisobenzofuranen
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
CA2354877C (en) 2000-08-18 2006-05-02 H. Lundbeck A/S Method for the preparation of citalopram
WO2001045483A2 (en) 2000-12-22 2001-06-28 H. Lundbeck A/S Method for the preparation of pure citalopram
US7148364B2 (en) * 2002-01-07 2006-12-12 Sun Pharmaceutical Industries Process for the preparation of 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofuran carbonitrile
AR040970A1 (es) 2002-08-12 2005-04-27 Lundbeck & Co As H Metodo para la separacion de intermediarios que pueden ser utilizados para la preparacion de escitalopram
WO2004085416A1 (en) * 2003-03-24 2004-10-07 Hetero Drugs Limited Novel crystalline forms of (s)-citalopram oxalate
US20050143350A1 (en) * 2003-11-19 2005-06-30 Seed John C. Combination drug therapy to treat obesity
CN100569765C (zh) 2003-12-19 2009-12-16 杭州民生药业集团有限公司 西酞普兰中间体晶体碱
US9339500B2 (en) * 2008-03-04 2016-05-17 Intra-Cellular Therapies, Inc. Methods of treating vasomotor symptoms
US20100087664A1 (en) * 2008-10-07 2010-04-08 Ravindra Vedantham Preparation of citalopram and salts thereof
JP6222973B2 (ja) * 2013-04-19 2017-11-01 日本テルペン化学株式会社 ジベンジルトリチオカーボネート誘導体
CN103936702A (zh) * 2014-05-07 2014-07-23 成都诺维尔生物医药有限公司 艾司西酞普兰杂质j的合成方法
EP3207018B1 (en) * 2014-10-14 2018-07-25 Syngenta Participations AG Process for the preparation of 1-(3,5-dichloro-4-fluoro-phenyl)-2,2,2-trifluoro-ethanone
CN118724848A (zh) * 2023-03-29 2024-10-01 中国石油化工股份有限公司 一种制备2,5-呋喃二甲腈的方法

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1143703A (is) 1965-03-18
GB1526331A (en) * 1976-01-14 1978-09-27 Kefalas As Phthalanes
GB8419963D0 (en) 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
GB8814057D0 (en) 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
DE3926765A1 (de) 1989-08-12 1991-02-14 Hoechst Ag Verfahren zur verminderung von primaerem und sekundaerem amin in einem tertiaeren amin
US5296507A (en) 1990-09-06 1994-03-22 H.Lundbeck A/S Treatment of cerbrovascular disorders
DK213290D0 (da) 1990-09-06 1990-09-06 Lundbeck & Co As H Treatment of cerebrovascular disorders
DE19626659A1 (de) 1996-07-03 1998-01-08 Basf Ag Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de) 1996-07-10 1998-01-15 Basf Ag Verfahren zur Herstellung von Phthaliden
ZA9711376B (en) 1996-12-20 1998-07-21 Lundbeck & Co As H Indole or dihydroindole derivatives
ES2148120T3 (es) 1997-07-08 2002-01-16 Lundbeck & Co As H Metodo para la preparacion de citalopram.
UA62985C2 (en) * 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
EA002770B1 (ru) 1997-11-11 2002-08-29 Х.Лундбекк А/С Способ получения циталопрама
PL199423B1 (pl) 1998-10-20 2008-09-30 Lundbeck & Co As H Sposób wytwarzania citalopramu
IL143422A0 (en) 1998-12-23 2002-04-21 Lundbeck & Co As H Method for the preparation of 5-cyanophthalide
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
DK1173431T4 (da) 1999-04-14 2010-01-04 Lundbeck & Co As H Fremgangsmåde til fremstilling af citalopram
ITMI991581A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991579A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
GB2360281B (en) 1999-10-25 2002-01-16 Lundbeck & Co As H Method for the preparation of citalopram
US6310222B1 (en) 1999-11-01 2001-10-30 Sumika Fine Chemicals Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
IES20010143A2 (en) 2000-02-24 2001-07-25 Lundbeck & Co As H Method for the preparation of citalopram
NL1017415C1 (nl) 2000-02-24 2001-05-18 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
GB0005477D0 (en) 2000-03-07 2000-04-26 Resolution Chemicals Limited Process for the preparation of citalopram
CA2354877C (en) 2000-08-18 2006-05-02 H. Lundbeck A/S Method for the preparation of citalopram
WO2001045483A2 (en) 2000-12-22 2001-06-28 H. Lundbeck A/S Method for the preparation of pure citalopram
JP2003519121A (ja) 2000-12-28 2003-06-17 ハー・ルンドベック・アクチエゼルスカベット 純粋なシタロプラムの製造方法

Also Published As

Publication number Publication date
AT5026U1 (de) 2002-02-25
ES2228920T3 (es) 2005-04-16
IS6048A (is) 2001-10-19
NO20013942D0 (no) 2001-08-14
CA2354877C (en) 2006-05-02
CN1339436A (zh) 2002-03-13
BG107584A (bg) 2004-01-30
AU7960901A (en) 2002-03-04
CN1239490C (zh) 2006-02-01
AR066694A2 (es) 2009-09-09
NO20013943L (no) 2002-02-19
CN1515564A (zh) 2004-07-28
US6509483B2 (en) 2003-01-21
CZ294746B6 (cs) 2005-03-16
AU2001100271A4 (en) 2001-09-13
FI20011621A7 (fi) 2002-02-19
RS50287B (sr) 2009-09-08
YU6903A (sh) 2006-05-25
KR20030022378A (ko) 2003-03-15
GR20010100398A (el) 2002-05-24
ES2170735B2 (es) 2003-09-16
PL359969A1 (en) 2004-09-06
MXPA03000913A (es) 2003-06-24
AU2001279608B2 (en) 2006-10-05
FR2813078A1 (fr) 2002-02-22
RS50258B (sr) 2009-07-15
YU11503A (sh) 2006-05-25
ES2170734A1 (es) 2002-08-01
AR029597A1 (es) 2003-07-10
SK3222003A3 (en) 2003-08-05
SK287008B6 (sk) 2009-09-07
CH691969A5 (de) 2001-12-14
NO326772B1 (no) 2009-02-16
UA72340C2 (uk) 2005-02-15
NL1018775C1 (nl) 2001-10-24
FR2813077B1 (fr) 2004-08-20
DE60106932D1 (de) 2004-12-09
WO2002016341A1 (en) 2002-02-28
CZ295863B6 (cs) 2005-11-16
BG65964B1 (bg) 2010-07-30
HUP0103291A2 (hu) 2002-05-29
NO20013943D0 (no) 2001-08-14
EP1309582A1 (en) 2003-05-14
GB0119733D0 (en) 2001-10-03
UA71676C2 (en) 2004-12-15
BG65965B1 (bg) 2010-07-30
HU0103291D0 (en) 2001-10-28
PT1309581E (pt) 2005-03-31
DE60106933D1 (de) 2004-12-09
HUP0103295A3 (en) 2005-01-28
IL144816A (en) 2005-09-25
CN1159307C (zh) 2004-07-28
IL144817A0 (en) 2002-06-30
BE1013444A6 (fr) 2002-01-15
SK287236B6 (sk) 2010-04-07
HK1044538B (zh) 2006-07-07
HRP20030064A2 (en) 2005-02-28
AT4946U1 (de) 2002-01-25
ATE281447T1 (de) 2004-11-15
GB2362647A (en) 2001-11-28
HK1044538A1 (en) 2002-10-25
DK1309582T3 (da) 2005-03-14
CZ20012958A3 (cs) 2002-04-17
CL2008002673A1 (es) 2009-01-02
KR20030022385A (ko) 2003-03-15
NO20013942L (no) 2002-02-19
IS2121B (is) 2006-06-15
CA2354877A1 (en) 2002-02-18
AU7960801A (en) 2002-03-04
HUP0103291A3 (en) 2003-02-28
PL359825A1 (pl) 2004-09-06
US20020026062A1 (en) 2002-02-28
CN1222517C (zh) 2005-10-12
BE1013443A6 (fr) 2002-01-15
AU2001100278B4 (en) 2001-11-29
ATE281448T1 (de) 2004-11-15
SK3202003A3 (en) 2003-08-05
GB2362647B (en) 2002-09-18
DE10140028A1 (de) 2002-04-18
DK200101219A (da) 2002-02-19
IL144816A0 (en) 2002-06-30
GB0119734D0 (en) 2001-10-03
ES2170735A1 (es) 2002-08-01
IES20010761A2 (en) 2002-02-20
JP2004506730A (ja) 2004-03-04
ES2230347T3 (es) 2005-05-01
AR029598A1 (es) 2003-07-10
DE60106933T2 (de) 2005-12-01
FI20011622A7 (fi) 2002-02-19
US20020025982A1 (en) 2002-02-28
KR100887206B1 (ko) 2009-03-06
SI1309581T1 (en) 2005-04-30
EP1309581A1 (en) 2003-05-14
EA200300277A1 (ru) 2003-08-28
NZ523877A (en) 2004-08-27
CN1339435A (zh) 2002-03-13
HK1047086B (zh) 2005-04-22
PT1309582E (pt) 2005-03-31
HK1068069A1 (en) 2005-04-22
CA2354880A1 (en) 2002-01-22
FI20011621A0 (fi) 2001-08-09
HUP0103295A2 (hu) 2002-05-29
IES20010760A2 (en) 2002-02-20
DE60106932T2 (de) 2005-11-03
HRP20030065A2 (en) 2005-02-28
FI20011621L (fi) 2002-02-19
ZA200106683B (en) 2002-08-05
EP1309581B1 (en) 2004-11-03
MXPA03001329A (es) 2003-06-06
HK1047086A1 (en) 2003-02-07
CA2354880C (en) 2003-06-03
IS2120B (is) 2006-06-15
CZ20012959A3 (cs) 2002-04-17
NL1018776C1 (nl) 2001-10-24
FI20011622L (fi) 2002-02-19
ES2170734B2 (es) 2003-09-16
EA200300279A1 (ru) 2003-08-28
EA005811B1 (ru) 2005-06-30
DK200101216A (da) 2002-02-19
MEP2308A (xx) 2010-02-10
FI20011622A0 (fi) 2001-08-09
EA005946B1 (ru) 2005-08-25
JP2004506729A (ja) 2004-03-04
AU2001279609B2 (en) 2007-09-06
FR2813078B1 (fr) 2004-04-02
AU2001100271B4 (en) 2001-11-29
IS6047A (is) 2001-10-20
EP1309582B1 (en) 2004-11-03
US6426422B1 (en) 2002-07-30
WO2002016342A1 (en) 2002-02-28
KR100887207B1 (ko) 2009-03-06
SI1309582T1 (en) 2005-06-30
CL2008002412A1 (es) 2009-01-02
NO326570B1 (no) 2009-01-12
BG107583A (bg) 2004-01-30
GB2365865B (en) 2002-07-17
AU2001100278A4 (en) 2001-09-13
DK1309581T3 (da) 2005-03-14
GR1004074B (el) 2002-11-26
NZ523853A (en) 2004-07-30
GB2365865A (en) 2002-02-27
CH691968A5 (de) 2001-12-14
DE10140029A1 (de) 2002-05-02
FR2813077A1 (fr) 2002-02-22

Similar Documents

Publication Publication Date Title
MEP2208A (xx) Postupak za pripremanje citaloprama
ES2149734T1 (es) Metodo para la preparacion de citalopram.
BG104116A (en) Method for the preparation of citalopram
EA200001135A1 (ru) Способ получения изоксазолин-3-ил-ацилбензолов
EA200100696A1 (ru) Способ получения 5-цианофталида
TNSN05167A1 (en) A process for preparing duloxetine and intermediates for use therein
RU95106678A (ru) Способ получения гинкголида в.
KR900009595A (ko) 2-클로로-5-클로로메틸피리딘의 제조방법
BR9809143A (pt) Processo para sintetizar composto
DE60324970D1 (de) Lösungsmittelfreies verfahren zur herstellung von diketopyrrolopyrrol-derivaten
ATE323703T1 (de) Synthese von verbindungen die zur herstellung von ketorolac dienen
BG107048A (en) Method for the preparation of citalopram
TR200002959A2 (tr) Pirazolo [4,3-D] pirimidin -7-onlar-3-piridilsülfonun bileşikleri ve bunların ara-bağlarının preparasyon işlemi
EA200501125A1 (ru) Способ получения метил-2-дифенилметилсульфинилацетата
GB2333293A (en) Process for the preparation of N-[2-(dimethylamino)ethyl]acridine-4-carboxamide
GR20010100397A (el) Μεθοδος παρασκευης της σιταλοπραμης.
DE50209655D1 (de) Mikrobiologisches verfahren zur herstellung von l-carnitin
BG103737A (en) Method for the preparation of derivatives of 4h-4-oxo-quinolysine-3-carboxylic acid
SG164282A1 (en) Taxane derivatives functionalized at the 14-position and a process for the preparation thereof
BG104486A (en) Method for the preparation of citalopram
NO20000869D0 (no) Fremgangsmåte for fremstilling av 1-(cyklopentenyloksy-4- alkoksyfenyl)-4-oksocykloheksankarbonitril
BR0105022A (pt) Método para preparação de citalopram, métodos para preparação de compostos utilizados na preparação do mesmo, citalopram e sua composição farmacêutica
BR9810499A (pt) Método e processo para preparação de citalopram; intermediário para tal preparação e sua composição farmacêutica antidepressiva
KR850005842A (ko) 질소-함유 포화 삼중환 디온
AU3001100A (en) Process for the preparation of 3,4-dihydroxybutanoic acid and derivatives thereof from substituted pentose sugars