NL1000565C2 - Complex van een insuline-analoog en protamine, dit complex bevattende farmaceutische formuleringen en bereidingswerkwijzen daarvan. - Google Patents

Complex van een insuline-analoog en protamine, dit complex bevattende farmaceutische formuleringen en bereidingswerkwijzen daarvan.

Info

Publication number
NL1000565C2
NL1000565C2 NL1000565A NL1000565A NL1000565C2 NL 1000565 C2 NL1000565 C2 NL 1000565C2 NL 1000565 A NL1000565 A NL 1000565A NL 1000565 A NL1000565 A NL 1000565A NL 1000565 C2 NL1000565 C2 NL 1000565C2
Authority
NL
Netherlands
Prior art keywords
complex
pharmaceutical formulations
preparation methods
insulin analog
containing pharmaceutical
Prior art date
Application number
NL1000565A
Other languages
English (en)
Dutch (nl)
Other versions
NL1000565A1 (nl
Inventor
Michael Rosario De Felippis
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22989963&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NL1000565(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of NL1000565A1 publication Critical patent/NL1000565A1/xx
Application granted granted Critical
Publication of NL1000565C2 publication Critical patent/NL1000565C2/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NL1000565A 1994-06-16 1995-06-14 Complex van een insuline-analoog en protamine, dit complex bevattende farmaceutische formuleringen en bereidingswerkwijzen daarvan. NL1000565C2 (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/260,633 US5461031A (en) 1994-06-16 1994-06-16 Monomeric insulin analog formulations

Publications (2)

Publication Number Publication Date
NL1000565A1 NL1000565A1 (nl) 1995-12-18
NL1000565C2 true NL1000565C2 (nl) 1996-12-03

Family

ID=22989963

Family Applications (2)

Application Number Title Priority Date Filing Date
NL1000565A NL1000565C2 (nl) 1994-06-16 1995-06-14 Complex van een insuline-analoog en protamine, dit complex bevattende farmaceutische formuleringen en bereidingswerkwijzen daarvan.
NL1004643A NL1004643C2 (nl) 1994-06-16 1996-11-29 Werkwijze voor het bereiden van kristallen van AspB28-menselijk insuline en protamine en deze kristallen bevattende farmaceutische formuleringen.

Family Applications After (1)

Application Number Title Priority Date Filing Date
NL1004643A NL1004643C2 (nl) 1994-06-16 1996-11-29 Werkwijze voor het bereiden van kristallen van AspB28-menselijk insuline en protamine en deze kristallen bevattende farmaceutische formuleringen.

Country Status (37)

Country Link
US (3) US5461031A (pt)
JP (1) JP3812962B2 (pt)
KR (1) KR100386038B1 (pt)
CN (1) CN1145641C (pt)
AT (1) AT408611B (pt)
BE (1) BE1009409A5 (pt)
BR (1) BR9502797A (pt)
CA (1) CA2151564C (pt)
CH (2) CH689934A5 (pt)
CO (1) CO4410204A1 (pt)
CZ (1) CZ294556B6 (pt)
DE (1) DE19521753B4 (pt)
DK (1) DK176213B1 (pt)
ES (1) ES2091728B1 (pt)
FI (1) FI118208B (pt)
FR (1) FR2721215B1 (pt)
GB (1) GB2290294B (pt)
GR (1) GR1002494B (pt)
HU (1) HU218943B (pt)
IE (1) IE68852B1 (pt)
IL (1) IL114153A (pt)
IT (1) IT1276722B1 (pt)
LU (1) LU88627A1 (pt)
MY (1) MY116831A (pt)
NL (2) NL1000565C2 (pt)
NO (1) NO320808B1 (pt)
NZ (1) NZ272360A (pt)
PE (1) PE34496A1 (pt)
PL (1) PL183284B1 (pt)
PT (1) PT101723B (pt)
RO (1) RO115124B1 (pt)
SE (1) SE509295C2 (pt)
SI (1) SI9500199A (pt)
TW (1) TW347334B (pt)
UA (1) UA34468C2 (pt)
YU (1) YU39795A (pt)
ZA (1) ZA954941B (pt)

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U. DEREWENDA ET AL.: "PHENOL STABILIZES MORE HELIX IN A NEW SYMMETRICAL ZINC INSULIN HEXAMER.", NATURE, vol. 338, 13 April 1989 (1989-04-13), LONDON GB, pages 594 - 596, XP002007532 *

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