|
US7179892B2
(en)
|
2000-12-06 |
2007-02-20 |
Neuralab Limited |
Humanized antibodies that recognize beta amyloid peptide
|
|
US6242195B1
(en)
|
1998-04-02 |
2001-06-05 |
Genentech, Inc. |
Methods for determining binding of an analyte to a receptor
|
|
US6528624B1
(en)
|
1998-04-02 |
2003-03-04 |
Genentech, Inc. |
Polypeptide variants
|
|
US6194551B1
(en)
|
1998-04-02 |
2001-02-27 |
Genentech, Inc. |
Polypeptide variants
|
|
HUP0104865A3
(en)
|
1999-01-15 |
2004-07-28 |
Genentech Inc |
Polypeptide variants with altered effector function
|
|
US7183387B1
(en)
|
1999-01-15 |
2007-02-27 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
|
US6737056B1
(en)
|
1999-01-15 |
2004-05-18 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
|
MXPA02008472A
(es)
|
2000-03-03 |
2004-03-26 |
Cambridge Antibody Tech |
Anticuerpos humanos contra la eotaxina y su uso.
|
|
JP2003531149A
(ja)
|
2000-04-13 |
2003-10-21 |
ザ・ロツクフエラー・ユニバーシテイ |
抗体由来の免疫応答の増強
|
|
US8163289B2
(en)
|
2001-03-09 |
2012-04-24 |
Iterative Therapeutics, Inc. |
Methods and compositions involving polymeric immunoglobulin fusion proteins
|
|
JP4524074B2
(ja)
|
2001-03-09 |
2010-08-11 |
アーナソン, バリー ジー. |
低親和性Fcγレセプターを標的化する重合体の免疫グロブリン融合タンパク質
|
|
GB0130543D0
(en)
|
2001-12-20 |
2002-02-06 |
Univ Cambridge Tech |
Human antibodies and their use
|
|
US7317091B2
(en)
|
2002-03-01 |
2008-01-08 |
Xencor, Inc. |
Optimized Fc variants
|
|
US8093357B2
(en)
|
2002-03-01 |
2012-01-10 |
Xencor, Inc. |
Optimized Fc variants and methods for their generation
|
|
US20040132101A1
(en)
|
2002-09-27 |
2004-07-08 |
Xencor |
Optimized Fc variants and methods for their generation
|
|
FI20020807A0
(fi)
*
|
2002-04-29 |
2002-04-29 |
Biotie Therapies Oyj |
Uusia humanisoituja anti-VAP-1 monoklonaalisia vasta-aineita
|
|
US7531178B2
(en)
|
2002-06-07 |
2009-05-12 |
Trigen Gmbh |
Immunoadhesin comprising a glycoprotein VI domain
|
|
EP1369128A1
(en)
|
2002-06-07 |
2003-12-10 |
Procorde GmbH |
Inhibitors of glycoprotein VI and their therapeutic use
|
|
US20070071744A1
(en)
|
2002-06-07 |
2007-03-29 |
Gotz Munch |
Agents which bind to epitopes of glycoprotein VI
|
|
US8946387B2
(en)
|
2002-08-14 |
2015-02-03 |
Macrogenics, Inc. |
FcγRIIB specific antibodies and methods of use thereof
|
|
US8968730B2
(en)
|
2002-08-14 |
2015-03-03 |
Macrogenics Inc. |
FcγRIIB specific antibodies and methods of use thereof
|
|
AU2003262650B2
(en)
*
|
2002-08-14 |
2009-10-29 |
Macrogenics, Inc. |
FcgammaRIIB-specific antibodies and methods of use thereof
|
|
SI2345671T1
(sl)
|
2002-09-27 |
2016-03-31 |
Xencor Inc. |
Optimizirane Fc-variante in postopki za njihovo izdelavo
|
|
AU2003304238A1
(en)
|
2002-10-08 |
2005-01-13 |
Rinat Neuroscience Corp. |
Methods for treating post-surgical pain by administering an anti-nerve growth factor antagonist antibody and compositions containing the same
|
|
UA80447C2
(en)
|
2002-10-08 |
2007-09-25 |
|
Methods for treating pain by administering nerve growth factor antagonist and opioid analgesic
|
|
PL211654B1
(pl)
|
2002-10-08 |
2012-06-29 |
Rinat Neuroscience Corp |
Przeciwciało skierowane przeciwko NGF do zastosowania w leczeniu bólu pooperacyjnego, zastosowanie tego przeciwciała do wytwarzania leku do leczenia bólu pooperacyjnego i kompozycja farmaceutyczna zawierająca przeciwciało skierowane przeciwko NGF do zastosowania w leczeniu bólu pooperacyjnego
|
|
US7365168B2
(en)
|
2002-10-15 |
2008-04-29 |
Pdl Biopharma, Inc. |
Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
|
|
US7217797B2
(en)
|
2002-10-15 |
2007-05-15 |
Pdl Biopharma, Inc. |
Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
|
|
SI1575517T1
(sl)
|
2002-12-24 |
2012-06-29 |
Rinat Neuroscience Corp |
Protitelesa proti ĺ˝iväśnemu rastnemu dejavniku in metode njihove uporabe
|
|
US9498530B2
(en)
|
2002-12-24 |
2016-11-22 |
Rinat Neuroscience Corp. |
Methods for treating osteoarthritis pain by administering a nerve growth factor antagonist and compositions containing the same
|
|
US7569364B2
(en)
|
2002-12-24 |
2009-08-04 |
Pfizer Inc. |
Anti-NGF antibodies and methods using same
|
|
EP2368578A1
(en)
|
2003-01-09 |
2011-09-28 |
Macrogenics, Inc. |
Identification and engineering of antibodies with variant Fc regions and methods of using same
|
|
US7960512B2
(en)
|
2003-01-09 |
2011-06-14 |
Macrogenics, Inc. |
Identification and engineering of antibodies with variant Fc regions and methods of using same
|
|
US8388955B2
(en)
|
2003-03-03 |
2013-03-05 |
Xencor, Inc. |
Fc variants
|
|
US20090010920A1
(en)
|
2003-03-03 |
2009-01-08 |
Xencor, Inc. |
Fc Variants Having Decreased Affinity for FcyRIIb
|
|
US8084582B2
(en)
|
2003-03-03 |
2011-12-27 |
Xencor, Inc. |
Optimized anti-CD20 monoclonal antibodies having Fc variants
|
|
EP2264073A1
(en)
|
2003-03-04 |
2010-12-22 |
Kirin Beer Kabushiki Kaisha |
Endothelial cell specific antibodies and uses thereof
|
|
WO2004087757A2
(en)
*
|
2003-04-03 |
2004-10-14 |
Laboratoire Francais Du Fractionnement Et Des Biotechnologies |
Antibodies with enhanced ability to immunomodulate cell functions
|
|
US9051373B2
(en)
|
2003-05-02 |
2015-06-09 |
Xencor, Inc. |
Optimized Fc variants
|
|
TWI353991B
(en)
|
2003-05-06 |
2011-12-11 |
Syntonix Pharmaceuticals Inc |
Immunoglobulin chimeric monomer-dimer hybrids
|
|
CA2530388A1
(en)
|
2003-06-27 |
2005-01-06 |
Biogen Idec Ma Inc. |
Modified binding molecules comprising connecting peptides
|
|
US7803376B2
(en)
|
2003-07-24 |
2010-09-28 |
Innate Pharma S.A. |
Methods and compositions for increasing the efficiency of therapeutic antibodies using NK cell potentiating compounds
|
|
NZ545776A
(en)
|
2003-08-22 |
2009-05-31 |
Biogen Idec Inc |
Improved antibodies having altered effector function and methods for making the same
|
|
US9714282B2
(en)
|
2003-09-26 |
2017-07-25 |
Xencor, Inc. |
Optimized Fc variants and methods for their generation
|
|
US8101720B2
(en)
|
2004-10-21 |
2012-01-24 |
Xencor, Inc. |
Immunoglobulin insertions, deletions and substitutions
|
|
JP2007531707A
(ja)
|
2003-10-15 |
2007-11-08 |
ピーディーエル バイオファーマ, インコーポレイテッド |
IGの重鎖定常領域の位置250、314および/または428の変異誘発によるFc融合タンパク質血清半減期の改変
|
|
GB0324368D0
(en)
*
|
2003-10-17 |
2003-11-19 |
Univ Cambridge Tech |
Polypeptides including modified constant regions
|
|
JP2008504002A
(ja)
|
2003-11-12 |
2008-02-14 |
バイオジェン・アイデック・エムエイ・インコーポレイテッド |
新生児Fcレセプター(FcRn)結合ポリペプチド改変体、ダイマーFc結合タンパク質、およびそれらに関連する方法
|
|
KR20070001932A
(ko)
|
2003-12-23 |
2007-01-04 |
리나트 뉴로사이언스 코퍼레이션 |
작용물질 항 티알케이씨 항체 및 그의 사용 방법
|
|
PL2311873T3
(pl)
|
2004-01-07 |
2019-01-31 |
Novartis Vaccines And Diagnostics, Inc. |
Przeciwciało monoklonalne specyficzne wobec M-CSF i jego zastosowania
|
|
EP1737890A2
(en)
|
2004-03-24 |
2007-01-03 |
Xencor, Inc. |
Immunoglobulin variants outside the fc region
|
|
EP1732949B1
(en)
|
2004-04-07 |
2010-01-27 |
Rinat Neuroscience Corp. |
Methods for treating bone cancer pain by administering a nerve growth factor antagonist
|
|
MXPA06012601A
(es)
|
2004-05-10 |
2007-05-10 |
Macrogenics Inc |
Anticuerpos especificos de fcy riib humanizados y metodos de uso de los mismos.
|
|
JP4651663B2
(ja)
|
2004-05-28 |
2011-03-16 |
アジェンシス,インコーポレイテッド |
Pscaタンパク質に結合する抗体および関連分子
|
|
AU2005272993B2
(en)
*
|
2004-07-15 |
2010-02-11 |
Xencor, Inc. |
Optimized Fc variants
|
|
US20150010550A1
(en)
|
2004-07-15 |
2015-01-08 |
Xencor, Inc. |
OPTIMIZED Fc VARIANTS
|
|
CZ200755A3
(cs)
|
2004-07-26 |
2007-04-11 |
Biogen Idec Ma Inc. |
Peptidy protilátek anti-CD154
|
|
CA2575663C
(en)
*
|
2004-07-30 |
2013-04-23 |
Rinat Neuroscience Corp. |
Antibodies directed against amyloid-beta peptide and methods using same
|
|
PL2213683T3
(pl)
|
2004-08-04 |
2013-10-31 |
Mentrik Biotech Llc |
WARIANTY REGIONÓW Fc
|
|
EP1778726A4
(en)
|
2004-08-16 |
2009-03-18 |
Medimmune Inc |
INTEGRIN ANTAGONISTS WITH IMPROVED ANTIBODY-DEPENDENT CELL-ASSAYED CYTOTOXICITY ACTIVITY
|
|
CN101023102B
(zh)
*
|
2004-09-17 |
2013-05-29 |
霍夫曼-拉罗奇有限公司 |
抗-ox40l抗体
|
|
TWI380996B
(zh)
|
2004-09-17 |
2013-01-01 |
Hoffmann La Roche |
抗ox40l抗體
|
|
BRPI0516962A
(pt)
*
|
2004-10-25 |
2008-09-30 |
Univ Northwestern |
anticorpo isolado, ou fragmento do mesmo, composição farmacêutica, métodos para prevenir a ligação de ligantes difundìveis derivados de abeta a um neurÈnio, para inibir a constituição de ligantes difundìveis, para bloquear a fosforilação de proteìna, para tratar profilaticamente ou terapeuticamente uma doença, para identificar um agente terapêutico, para detectar ligantes difundìveis, e para diagnosticar uma doença, e, kit para detectar ligantes difundìveis
|
|
US7632497B2
(en)
|
2004-11-10 |
2009-12-15 |
Macrogenics, Inc. |
Engineering Fc Antibody regions to confer effector function
|
|
US8367805B2
(en)
|
2004-11-12 |
2013-02-05 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
|
US8546543B2
(en)
|
2004-11-12 |
2013-10-01 |
Xencor, Inc. |
Fc variants that extend antibody half-life
|
|
EP2332985A3
(en)
|
2004-11-12 |
2012-01-25 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
|
RU2412200C2
(ru)
*
|
2004-11-12 |
2011-02-20 |
Ксенкор, Инк. |
Fc-ВАРИАНТЫ С ИЗМЕНЕННЫМ СВЯЗЫВАНИЕМ С FcRn
|
|
US8802820B2
(en)
|
2004-11-12 |
2014-08-12 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
|
US7700099B2
(en)
|
2005-02-14 |
2010-04-20 |
Merck & Co., Inc. |
Non-immunostimulatory antibody and compositions containing the same
|
|
CN105535967B
(zh)
|
2005-02-15 |
2022-05-03 |
杜克大学 |
抗cd19抗体及其在肿瘤学中的应用
|
|
EP2444099A1
(en)
|
2005-03-31 |
2012-04-25 |
Agensys, Inc. |
Antibodies and related molecules that bind to 161P2F10B proteins
|
|
TWI544076B
(zh)
|
2005-03-31 |
2016-08-01 |
中外製藥股份有限公司 |
A method of manufacturing a polypeptide that controls assembly
|
|
US9284375B2
(en)
|
2005-04-15 |
2016-03-15 |
Macrogenics, Inc. |
Covalent diabodies and uses thereof
|
|
US11254748B2
(en)
|
2005-04-15 |
2022-02-22 |
Macrogenics, Inc. |
Covalent diabodies and uses thereof
|
|
US9963510B2
(en)
|
2005-04-15 |
2018-05-08 |
Macrogenics, Inc. |
Covalent diabodies and uses thereof
|
|
CA2605024C
(en)
|
2005-04-15 |
2018-05-22 |
Macrogenics, Inc. |
Covalent diabodies and uses thereof
|
|
WO2006116260A2
(en)
|
2005-04-26 |
2006-11-02 |
Medimmune, Inc. |
Modulation of antibody effector function by hinge domain engineering
|
|
PE20061323A1
(es)
*
|
2005-04-29 |
2007-02-09 |
Rinat Neuroscience Corp |
Anticuerpos dirigidos contra el peptido amiloide beta y metodos que utilizan los mismos
|
|
EP1885755A4
(en)
|
2005-05-05 |
2009-07-29 |
Univ Duke |
CD19 ANTIBODY THERAPY FOR AUTOIMMUNE DISEASES
|
|
AU2006261920A1
(en)
|
2005-06-23 |
2007-01-04 |
Medimmune, Llc |
Antibody formulations having optimized aggregation and fragmentation profiles
|
|
EP1899477A4
(en)
|
2005-07-01 |
2010-01-20 |
Medimmune Inc |
INTEGRATED APPROACH FOR GENERATING MULTIDOMAIN PROTEIN THERAPEUTIC APPLICATIONS
|
|
US7557190B2
(en)
|
2005-07-08 |
2009-07-07 |
Xencor, Inc. |
Optimized proteins that target Ep-CAM
|
|
JP4997239B2
(ja)
|
2005-07-22 |
2012-08-08 |
ワイズ・エー・シー株式会社 |
抗cd26抗体およびその使用方法
|
|
WO2007016285A2
(en)
|
2005-07-28 |
2007-02-08 |
Novartis Ag |
M-csf specific monoclonal antibody and uses thereof
|
|
SI2573114T1
(sl)
|
2005-08-10 |
2016-08-31 |
Macrogenics, Inc. |
Identifikacija in inženiring protiteles z variantnimi fc regijami in postopki za njih uporabo
|
|
CA2624189A1
(en)
|
2005-10-03 |
2007-04-12 |
Xencor, Inc. |
Fc variants with optimized fc receptor binding properties
|
|
AU2006302254B2
(en)
|
2005-10-06 |
2011-05-26 |
Xencor, Inc. |
Optimized anti-CD30 antibodies
|
|
EP1943332A4
(en)
|
2005-10-14 |
2011-04-13 |
Medimmune Inc |
CELLULAR DISPLAY OF ANTIBODY LIBRARIES
|
|
SI3045182T1
(en)
|
2005-11-14 |
2018-08-31 |
Teva Pharmaceuticals International Gmbh |
An antibody to a peptide-associated peptide antagonist to calcitonin for treating a headache in aggregates
|
|
TWI461436B
(zh)
*
|
2005-11-25 |
2014-11-21 |
Kyowa Hakko Kirin Co Ltd |
人類cd134(ox40)之人類單株抗體及其製造及使用方法
|
|
WO2007103469A2
(en)
|
2006-03-06 |
2007-09-13 |
Aeres Biomedical Ltd. |
Humanized anti-cd22 antibodies and their use in treatment of oncology, transplantation and autoimmune disease
|
|
CA2645159A1
(en)
|
2006-03-10 |
2008-06-26 |
Michael S. Urdea |
Multiplex protein fractionation
|
|
JP2009529915A
(ja)
|
2006-03-20 |
2009-08-27 |
ゾーマ テクノロジー リミテッド |
ガストリン物質に対して特異的なヒト抗体および方法
|
|
CA2647846C
(en)
|
2006-03-31 |
2016-06-21 |
Chugai Seiyaku Kabushiki Kaisha |
Methods for controlling blood pharmacokinetics of antibodies
|
|
JP5144499B2
(ja)
|
2006-03-31 |
2013-02-13 |
中外製薬株式会社 |
二重特異性抗体を精製するための抗体改変方法
|
|
EP2044120B1
(en)
|
2006-06-07 |
2019-01-30 |
BioAlliance C.V. |
Antibodies recognizing a carbohydrate containing epitope on cd-43 and cea expressed on cancer cells and methods using same
|
|
LT2029173T
(lt)
|
2006-06-26 |
2016-11-10 |
Macrogenics, Inc. |
Fc riib specifiniai antikūnai ir jų panaudojimo būdai
|
|
CA2656224C
(en)
|
2006-06-26 |
2018-01-09 |
Macrogenics, Inc. |
Combination of fc.gamma.riib antibodies and cd20-specific antibodies and methods of use thereof
|
|
CA2659820A1
(en)
|
2006-08-04 |
2008-02-14 |
Novartis Ag |
Ephb3-specific antibody and uses thereof
|
|
SI2383297T1
(sl)
|
2006-08-14 |
2013-06-28 |
Xencor Inc. |
Optimizirana antitelesa, ki ciljajo cd19
|
|
SI2059535T1
(sl)
|
2006-08-18 |
2014-03-31 |
Novartis Ag |
Za prlr specifiäśno protitelo in njegove uporabe
|
|
CN103694349A
(zh)
|
2006-09-08 |
2014-04-02 |
米迪缪尼有限公司 |
人源化抗cd19抗体及其在治疗癌症、移植病和自身免疫病中的应用
|
|
WO2008036688A2
(en)
|
2006-09-18 |
2008-03-27 |
Xencor, Inc. |
Optimized antibodies that target hm1.24
|
|
EA200900767A1
(ru)
|
2006-12-07 |
2009-12-30 |
Новартис Аг |
Антагонистические антитела против ephb3
|
|
WO2008140603A2
(en)
|
2006-12-08 |
2008-11-20 |
Macrogenics, Inc. |
METHODS FOR THE TREATMENT OF DISEASE USING IMMUNOGLOBULINS HAVING FC REGIONS WITH ALTERED AFFINITIES FOR FCγR ACTIVATING AND FCγR INHIBITING
|
|
AU2016203577B2
(en)
*
|
2007-01-30 |
2017-12-21 |
Epivax, Inc. |
Regulatory T cell epitopes, compositions and uses thereof
|
|
CN107011431B
(zh)
|
2007-01-30 |
2020-11-06 |
埃皮瓦克斯公司 |
调节性t细胞表位、组合物及其用途
|
|
US8637016B2
(en)
|
2007-03-08 |
2014-01-28 |
Kalobios Pharmaceuticals, Inc. |
EphA3 antibodies for the treatment of solid tumors
|
|
WO2008118324A2
(en)
|
2007-03-26 |
2008-10-02 |
Macrogenics, Inc. |
Composition and method of treating cancer with an anti-uroplakin ib antibody
|
|
AU2008232311A1
(en)
*
|
2007-03-27 |
2008-10-02 |
Niall Corcoran |
Methods and compositions for treating prostate cancer
|
|
EP2737907A3
(en)
|
2007-05-07 |
2014-11-05 |
MedImmune, LLC |
Anti-icos antibodies and their use in treatment of oncology, transplantation and autoimmune disease
|
|
CA2685222C
(en)
|
2007-05-14 |
2017-12-19 |
Medimmune, Llc |
Methods of reducing eosinophil levels
|
|
ES2528167T3
(es)
|
2007-06-15 |
2015-02-04 |
Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts |
Tratamiento de tumores usando anticuerpo anti-L1, específico.
|
|
EP2158221B1
(en)
|
2007-06-21 |
2018-08-29 |
MacroGenics, Inc. |
Covalent diabodies and uses thereof
|
|
WO2009018386A1
(en)
|
2007-07-31 |
2009-02-05 |
Medimmune, Llc |
Multispecific epitope binding proteins and uses thereof
|
|
PE20090499A1
(es)
|
2007-08-09 |
2009-05-18 |
Boehringer Ingelheim Int |
Anticuerpos anti-cd37
|
|
SG193868A1
(en)
|
2007-09-26 |
2013-10-30 |
Chugai Pharmaceutical Co Ltd |
Modified antibody constant region
|
|
RU2510400C9
(ru)
|
2007-09-26 |
2014-07-20 |
Чугаи Сейяку Кабусики Кайся |
Способ модификации изоэлектрической точки антитела с помощью аминокислотных замен в cdr
|
|
PE20091205A1
(es)
|
2007-09-26 |
2009-09-09 |
Chugai Pharmaceutical Co Ltd |
Anticuerpo anti-receptor de il-6
|
|
JO3076B1
(ar)
|
2007-10-17 |
2017-03-15 |
Janssen Alzheimer Immunotherap |
نظم العلاج المناعي المعتمد على حالة apoe
|
|
TWI548418B
(zh)
|
2007-12-05 |
2016-09-11 |
中外製藥股份有限公司 |
Anti-NR10 / IL-31RA antibody and its use
|
|
CA2709135C
(en)
|
2007-12-17 |
2018-06-05 |
Pfizer Limited |
Treatment of interstitial cystitis
|
|
ES2550757T3
(es)
|
2007-12-18 |
2015-11-12 |
Bioalliance C.V. |
Anticuerpos que reconocen un epítopo que contiene carbohidratos en CD43 y ACE expresados en células cancerosas y métodos de uso de los mismos
|
|
US8795667B2
(en)
|
2007-12-19 |
2014-08-05 |
Macrogenics, Inc. |
Compositions for the prevention and treatment of smallpox
|
|
JP5571567B2
(ja)
|
2007-12-21 |
2014-08-13 |
メディミューン リミテッド |
インターロイキン−4受容体α(IL−4Rα)−173に対する結合メンバー
|
|
US8092804B2
(en)
|
2007-12-21 |
2012-01-10 |
Medimmune Limited |
Binding members for interleukin-4 receptor alpha (IL-4Rα)-173
|
|
DK2235059T3
(en)
|
2007-12-26 |
2015-03-30 |
Xencor Inc |
FC-VERSIONS OF MODIFIED BINDING TO FcRn
|
|
US20110033378A1
(en)
|
2008-01-18 |
2011-02-10 |
Medlmmune, Llc. |
Cysteine Engineered Antibodies For Site-Specific Conjugation
|
|
HUE032025T2
(en)
|
2008-01-31 |
2017-08-28 |
Inserm - Inst Nat De La Sante Et De La Rech Medicale |
Antibodies to human CD39 and their use to inhibit regulatory T cell activity
|
|
MX2010008578A
(es)
|
2008-02-08 |
2010-11-10 |
Medimmune Llc |
Anticuerpos anti-receptor 1 de interferon alfa con afinidad reducida al ligando fc.
|
|
US12492253B1
(en)
|
2008-02-25 |
2025-12-09 |
Xencor, Inc. |
Anti-human C5 antibodies
|
|
EP2265287B1
(en)
|
2008-03-04 |
2018-09-05 |
Teva Pharmaceuticals International GmbH |
Methods of treating chronic pain
|
|
WO2009109908A1
(en)
|
2008-03-04 |
2009-09-11 |
Pfizer Limited |
Methods of treating inflammatory pain
|
|
HUE044239T2
(hu)
|
2008-03-27 |
2019-10-28 |
Purdue Research Foundation |
Kollagén-kötõ szintetikus peptidoglikánok, elõállításuk és alkalmazási eljárásaik
|
|
CA2720365C
(en)
|
2008-04-02 |
2019-01-15 |
Macrogenics, Inc. |
Bcr-complex-specific antibodies and methods of using same
|
|
SG189730A1
(en)
|
2008-04-02 |
2013-05-31 |
Macrogenics Inc |
Her2/neu-specific antibodies and methods of using same
|
|
TW201920257A
(zh)
|
2008-04-11 |
2019-06-01 |
日商中外製藥股份有限公司 |
重複結合複數個抗原的抗原結合分子
|
|
BRPI0910622A2
(pt)
*
|
2008-04-25 |
2020-03-10 |
Dyax Corp. |
ANTICORPOS CONTRA FcRn E USOS DOS MESMOS
|
|
ES2675730T3
(es)
|
2008-06-04 |
2018-07-12 |
Macrogenics, Inc. |
Anticuerpos con unión alterada a FcRn y métodos de uso de los mismos
|
|
WO2009150623A1
(en)
|
2008-06-13 |
2009-12-17 |
Pfizer Inc |
Treatment of chronic prostatitis
|
|
TWI516501B
(zh)
|
2008-09-12 |
2016-01-11 |
禮納特神經系統科學公司 |
Pcsk9拮抗劑類
|
|
WO2010032060A1
(en)
|
2008-09-19 |
2010-03-25 |
Medimmune Llc |
Antibodies directed to dll4 and uses thereof
|
|
WO2010032220A1
(en)
|
2008-09-19 |
2010-03-25 |
Pfizer Inc. |
Stable liquid antibody formulation
|
|
TWI440469B
(zh)
|
2008-09-26 |
2014-06-11 |
Chugai Pharmaceutical Co Ltd |
Improved antibody molecules
|
|
GB0817891D0
(en)
|
2008-09-30 |
2008-11-05 |
Medical Res Council |
Antibodies against il-25
|
|
US8298533B2
(en)
|
2008-11-07 |
2012-10-30 |
Medimmune Limited |
Antibodies to IL-1R1
|
|
EP2358392B1
(en)
|
2008-11-12 |
2019-01-09 |
MedImmune, LLC |
Antibody formulation
|
|
CN102369021B
(zh)
|
2008-12-19 |
2016-09-07 |
宏观基因有限公司 |
共价双抗体及其用途
|
|
JP2012513194A
(ja)
|
2008-12-23 |
2012-06-14 |
アストラゼネカ アクチボラグ |
α5β1に向けられた標的結合剤およびその使用
|
|
AU2009334498A1
(en)
|
2008-12-31 |
2011-07-21 |
Biogen Idec Ma Inc. |
Anti-lymphotoxin antibodies
|
|
WO2010086828A2
(en)
|
2009-02-02 |
2010-08-05 |
Rinat Neuroscience Corporation |
Agonist anti-trkb monoclonal antibodies
|
|
WO2010096394A2
(en)
|
2009-02-17 |
2010-08-26 |
Redwood Biosciences, Inc. |
Aldehyde-tagged protein-based drug carriers and methods of use
|
|
GB0903325D0
(en)
|
2009-02-26 |
2009-04-08 |
Univ Aberdeen |
Antibody molecules
|
|
WO2010102244A1
(en)
|
2009-03-06 |
2010-09-10 |
Kalobios Pharmaceuticals, Inc. |
Treatment of leukemias and chronic myeloproliferative diseases with antibodies to epha3
|
|
WO2010107109A1
(ja)
|
2009-03-19 |
2010-09-23 |
中外製薬株式会社 |
抗体定常領域改変体
|
|
JP5717624B2
(ja)
|
2009-03-19 |
2015-05-13 |
中外製薬株式会社 |
抗体定常領域改変体
|
|
GB0905972D0
(en)
|
2009-04-06 |
2009-05-20 |
Medical Res Council |
Antibodies against IL-17BR
|
|
US20100297127A1
(en)
|
2009-04-08 |
2010-11-25 |
Ghilardi Nico P |
Use of il-27 antagonists to treat lupus
|
|
GB0908425D0
(en)
|
2009-05-15 |
2009-06-24 |
Medical Res Council |
Medical use
|
|
TW201041595A
(en)
|
2009-05-15 |
2010-12-01 |
Chugai Pharmaceutical Co Ltd |
Anti-axl antibody
|
|
WO2010146511A1
(en)
|
2009-06-17 |
2010-12-23 |
Pfizer Limited |
Treatment of overactive bladder
|
|
US9090690B2
(en)
|
2009-06-18 |
2015-07-28 |
Pfizer Inc. |
Anti Notch-1 antibodies
|
|
WO2011005481A1
(en)
|
2009-06-22 |
2011-01-13 |
Medimmune, Llc |
ENGINEERED Fc REGIONS FOR SITE-SPECIFIC CONJUGATION
|
|
JP2013502458A
(ja)
|
2009-08-24 |
2013-01-24 |
アムニクス オペレーティング インコーポレイテッド |
凝固第vii因子組成物ならびにそれを製造および使用する方法
|
|
WO2011024113A1
(en)
|
2009-08-28 |
2011-03-03 |
Rinat Neuroscience Corporation |
Methods for treating visceral pain by administering antagonist antibodies directed against calcitonin gene-related peptide
|
|
WO2011028952A1
(en)
|
2009-09-02 |
2011-03-10 |
Xencor, Inc. |
Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
|
|
CA2771336C
(en)
|
2009-09-15 |
2019-11-26 |
The Board Of Trustees Of The Leland Stanford Junior University |
Synergistic anti-cd47 therapy for hematologic cancers
|
|
WO2011037158A1
(ja)
|
2009-09-24 |
2011-03-31 |
中外製薬株式会社 |
抗体定常領域改変体
|
|
CA2772945A1
(en)
|
2009-09-25 |
2011-03-31 |
Xoma Technology Ltd. |
Screening methods
|
|
US8926976B2
(en)
|
2009-09-25 |
2015-01-06 |
Xoma Technology Ltd. |
Modulators
|
|
CA2776385C
(en)
|
2009-10-07 |
2019-04-09 |
Macrogenics, Inc. |
Fc region-containing polypeptides that exhibit improved effector function due to alterations of the extent of fucosylation, and methods for their use
|
|
EP2488554B1
(en)
|
2009-10-14 |
2019-07-24 |
Humanigen, Inc. |
Antibodies to epha3
|
|
US8519107B2
(en)
|
2009-10-30 |
2013-08-27 |
Janssen Biotech, Inc. |
IL-17A antibodies
|
|
SG10201912571XA
(en)
|
2009-11-02 |
2020-02-27 |
Univ Washington |
Therapeutic nuclease compositions and methods
|
|
EP2497498A4
(en)
|
2009-11-05 |
2013-04-17 |
Univ Osaka |
THERAPEUTIC ACTIVE FOR AUTOIMMUNE DISEASES OR ALLERGIES AND METHOD FOR SCREENING AFTER THE THERAPEUTIC ACTIVE SUBSTANCE
|
|
LT2504364T
(lt)
|
2009-11-24 |
2017-11-10 |
Medimmune Limited |
Tiksliniai surišantys agentai prieš b7-h1
|
|
EA201890907A1
(ru)
*
|
2009-11-30 |
2020-04-30 |
Янссен Байотек, Инк. |
МУТИРОВАННЫЕ Fc АНТИТЕЛА С УСТРАНЕННЫМИ ЭФФЕКТОРНЫМИ ФУНКЦИЯМИ
|
|
WO2011064758A2
(en)
*
|
2009-11-30 |
2011-06-03 |
Pfizer Limited |
Fusion protein
|
|
US10053513B2
(en)
|
2009-11-30 |
2018-08-21 |
Janssen Biotech, Inc. |
Antibody Fc mutants with ablated effector functions
|
|
US8362210B2
(en)
|
2010-01-19 |
2013-01-29 |
Xencor, Inc. |
Antibody variants with enhanced complement activity
|
|
MX2012008884A
(es)
|
2010-02-08 |
2012-08-31 |
Agensys Inc |
Conjugados de anticuerpo y farmaco (adc) que se unen a proteinas 161p2f10b.
|
|
JP5841072B2
(ja)
|
2010-02-10 |
2016-01-06 |
イミュノジェン・インコーポレーテッド |
Cd20抗体およびその使用
|
|
AR080291A1
(es)
|
2010-02-24 |
2012-03-28 |
Rinat Neuroscience Corp |
Anticuerpos antagonistas anti receptor de il-7 y procedimientos
|
|
LT2542256T
(lt)
|
2010-03-04 |
2019-10-25 |
Macrogenics Inc |
Su b7-h3 reaguojantys antikūnai, jų imunologiškai aktyvūs fragmentai ir jų naudojimas
|
|
EP2543730B1
(en)
*
|
2010-03-04 |
2018-10-31 |
Chugai Seiyaku Kabushiki Kaisha |
Antibody constant region variant
|
|
PH12012501751A1
(en)
|
2010-03-04 |
2012-11-12 |
Macrogenics Inc |
Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof
|
|
CN105218674A
(zh)
|
2010-03-11 |
2016-01-06 |
瑞纳神经科学公司 |
呈pH依赖性抗原结合的抗体
|
|
EP3208281A1
(en)
|
2010-03-29 |
2017-08-23 |
Zymeworks, Inc. |
Antibodies with enhanced or suppressed effector function
|
|
WO2011123507A1
(en)
|
2010-03-30 |
2011-10-06 |
Centocor Ortho Biotech Inc. |
Humanized il-25 antibodies
|
|
WO2011133931A1
(en)
|
2010-04-22 |
2011-10-27 |
Genentech, Inc. |
Use of il-27 antagonists for treating inflammatory bowel disease
|
|
AU2011270862B2
(en)
*
|
2010-06-23 |
2017-05-11 |
Purdue Research Foundation |
Collagen-binding synthetic peptidoglycans for use in vascular intervention
|
|
DK2591099T3
(da)
|
2010-07-09 |
2021-02-15 |
Bioverativ Therapeutics Inc |
Kimære koagulationsfaktorer
|
|
CN103154025B
(zh)
|
2010-08-02 |
2015-07-01 |
宏观基因有限公司 |
共价双抗体及其用途
|
|
CA2808154A1
(en)
|
2010-08-13 |
2012-02-16 |
Medimmmune Limited |
Monomeric polypeptides comprising variant fc regions and methods of use
|
|
WO2012022734A2
(en)
|
2010-08-16 |
2012-02-23 |
Medimmune Limited |
Anti-icam-1 antibodies and methods of use
|
|
WO2012024650A2
(en)
|
2010-08-19 |
2012-02-23 |
Abbott Laboratories |
Anti-ngf antibodies and their use
|
|
US8637642B2
(en)
|
2010-09-29 |
2014-01-28 |
Seattle Genetics, Inc. |
Antibody drug conjugates (ADC) that bind to 191P4D12 proteins
|
|
UA112062C2
(uk)
|
2010-10-04 |
2016-07-25 |
Бьорінгер Інгельхайм Інтернаціональ Гмбх |
Cd33-зв'язувальний агент
|
|
GB201016864D0
(en)
|
2010-10-06 |
2010-11-17 |
Univ Aston |
Therapeutic methods
|
|
CA2815266C
(en)
|
2010-11-05 |
2023-09-05 |
Zymeworks Inc. |
Stable heterodimeric antibody design with mutations in the fc domain
|
|
KR101398290B1
(ko)
|
2010-11-17 |
2014-05-22 |
추가이 세이야쿠 가부시키가이샤 |
혈액응고 제viii 인자의 기능을 대체하는 기능을 갖는 다중특이성 항원 결합 분자
|
|
MX349057B
(es)
|
2010-11-30 |
2017-07-07 |
Chugai Pharmaceutical Co Ltd |
Agente terapeutico que induce citotoxicidad.
|
|
SG10201509790YA
(en)
|
2010-11-30 |
2015-12-30 |
Chugai Pharmaceutical Co Ltd |
Antigen-Binding Molecule Capable Of Binding To Plurality Of Antigen Molecules Repeatedly
|
|
PE20141109A1
(es)
|
2010-12-15 |
2014-09-24 |
Wyeth Llc |
Anticuerpos anti-notch 1
|
|
AU2012205301B2
(en)
|
2011-01-14 |
2017-01-05 |
Redwood Bioscience, Inc. |
Aldehyde-tagged immunoglobulin polypeptides and method of use thereof
|
|
SG10201609665PA
(en)
|
2011-02-25 |
2017-01-27 |
Chugai Pharmaceutical Co Ltd |
FcɣRIIb-SPECIFIC Fc ANTIBODY
|
|
HUE041335T2
(hu)
|
2011-03-29 |
2019-05-28 |
Roche Glycart Ag |
Antitest FC-variánsok
|
|
PT2699264T
(pt)
|
2011-04-20 |
2018-05-23 |
Medimmune Llc |
Anticorpos e outras moléculas que ligam b7-h1 e pd-1
|
|
GB201107170D0
(en)
|
2011-04-28 |
2011-06-15 |
Clark Michael |
Binding molecules with biased recognition
|
|
CA2834626A1
(en)
|
2011-04-29 |
2012-11-01 |
University Of Washington |
Therapeutic nuclease compositions and methods
|
|
RS58765B1
(sr)
|
2011-05-21 |
2019-06-28 |
Macrogenics Inc |
Cd3-vezujući molekuli sposobni za vezivanje za humani i nehumani cd3
|
|
JP6145088B2
(ja)
|
2011-05-21 |
2017-06-07 |
マクロジェニクス,インコーポレーテッド |
脱免疫化血清結合ドメイン及び血清半減期を延長するためのその使用
|
|
ES2704038T3
(es)
|
2011-05-24 |
2019-03-13 |
Zyngenia Inc |
Complejos multiespecíficos multivalentes y monovalentes y sus usos
|
|
BR112013030352B1
(pt)
|
2011-06-02 |
2020-05-19 |
Dyax Corp. |
anticorpo anti-fcrn isolado, composição farmacêutica que compreende o dito anticorpo, ácido nucleico isolado, vetor, célula e uso terapêutico do dito anticorpo
|
|
AU2012261933B2
(en)
|
2011-06-03 |
2017-06-15 |
Xoma Technology Ltd. |
Antibodies specific for TGF-beta
|
|
WO2012170740A2
(en)
|
2011-06-07 |
2012-12-13 |
University Of Hawaii |
Biomarker of asbestos exposure and mesothelioma
|
|
WO2012170742A2
(en)
|
2011-06-07 |
2012-12-13 |
University Of Hawaii |
Treatment and prevention of cancer with hmgb1 antagonists
|
|
HUE043894T2
(hu)
|
2011-06-10 |
2019-09-30 |
Bioverativ Therapeutics Inc |
Koagulációt elõsegítõ vegyületek és alkalmazásuk módszerei
|
|
RU2641256C2
(ru)
|
2011-06-30 |
2018-01-16 |
Чугаи Сейяку Кабусики Кайся |
Гетеродимеризованный полипептид
|
|
JP2013040160A
(ja)
|
2011-07-01 |
2013-02-28 |
Genentech Inc |
自己免疫疾患を治療するための抗cd83アゴニスト抗体の使用
|
|
RU2576034C2
(ru)
|
2011-07-14 |
2016-02-27 |
Пфайзер Инк. |
Лечение антителами против pcsk9
|
|
WO2013012733A1
(en)
|
2011-07-15 |
2013-01-24 |
Biogen Idec Ma Inc. |
Heterodimeric fc regions, binding molecules comprising same, and methods relating thereto
|
|
US9676854B2
(en)
|
2011-08-15 |
2017-06-13 |
Medimmune, Llc |
Anti-B7-H4 antibodies and their uses
|
|
UY34317A
(es)
|
2011-09-12 |
2013-02-28 |
Genzyme Corp |
Anticuerpo antireceptor de célula T (alfa)/ß
|
|
US20130108641A1
(en)
|
2011-09-14 |
2013-05-02 |
Sanofi |
Anti-gitr antibodies
|
|
TW201817745A
(zh)
|
2011-09-30 |
2018-05-16 |
日商中外製藥股份有限公司 |
具有促進抗原清除之FcRn結合域的治療性抗原結合分子
|
|
JP6322411B2
(ja)
|
2011-09-30 |
2018-05-09 |
中外製薬株式会社 |
複数の生理活性を有する抗原の消失を促進する抗原結合分子
|
|
MX359775B
(es)
|
2011-10-31 |
2018-10-10 |
Chugai Pharmaceutical Co Ltd |
Molecula enlazada al antigeno que tiene conjugacion regulada entre cadena ligera y cadena pesada.
|
|
WO2013067060A1
(en)
|
2011-11-01 |
2013-05-10 |
Bionomics, Inc. |
Anti-gpr49 antibodies
|
|
JP2014533247A
(ja)
|
2011-11-01 |
2014-12-11 |
バイオノミクス インコーポレイテッド |
抗体および癌を治療する方法
|
|
AU2012332590B2
(en)
|
2011-11-01 |
2016-10-20 |
Bionomics, Inc. |
Anti-GPR49 antibodies
|
|
ES2697674T3
(es)
|
2011-11-01 |
2019-01-25 |
Bionomics Inc |
Procedimientos para bloquear el crecimiento de células madre cancerosas
|
|
CN109897103B
(zh)
|
2011-11-04 |
2024-05-17 |
酵活英属哥伦比亚有限公司 |
在Fc结构域中具有突变的稳定异源二聚的抗体设计
|
|
JP2014533249A
(ja)
|
2011-11-07 |
2014-12-11 |
メディミューン,エルエルシー |
多重特異性を持つ多価結合タンパク質およびその使用
|
|
CN104053672A
(zh)
|
2011-11-11 |
2014-09-17 |
瑞纳神经科学公司 |
Trop-2特异性抗体及其用途
|
|
CN113416257A
(zh)
|
2011-11-30 |
2021-09-21 |
中外制药株式会社 |
包含进入细胞内以形成免疫复合体的搬运体(载体)的药物
|
|
JP6483442B2
(ja)
|
2011-12-05 |
2019-03-13 |
エックス−ボディ インコーポレイテッド |
Pdgf受容体ベータ結合ポリペプチド
|
|
JP6441079B2
(ja)
*
|
2011-12-19 |
2018-12-19 |
シンイミューン ゲーエムベーハー |
二重特異性抗体分子
|
|
SI2794905T1
(sl)
|
2011-12-20 |
2020-08-31 |
Medimmune, Llc |
Modificirani polipeptidi za ogrodja bispecifičnega protitelesa
|
|
WO2013093693A1
(en)
|
2011-12-22 |
2013-06-27 |
Rinat Neuroscience Corp. |
Staphylococcus aureus specific antibodies and uses thereof
|
|
AU2012356206A1
(en)
|
2011-12-22 |
2014-06-26 |
Rinat Neuroscience Corp. |
Human growth hormone receptor antagonist antibodies and methods of use thereof
|
|
CA3111357A1
(en)
|
2011-12-23 |
2013-06-27 |
Pfizer Inc. |
Engineered antibody constant regions for site-specific conjugation and methods and uses therefor
|
|
MX357403B
(es)
|
2012-01-12 |
2018-07-09 |
Bioverativ Therapeutics Inc |
Polipeptidos de factor viii quimericos y usos de los mismos.
|
|
CA2862101A1
(en)
|
2012-02-07 |
2013-08-15 |
Innate Pharma |
Mica binding agents
|
|
CN104204204A
(zh)
|
2012-02-09 |
2014-12-10 |
中外制药株式会社 |
抗体的Fc区变异体
|
|
BR112014020694A2
(pt)
|
2012-02-15 |
2018-05-08 |
Amunix Operating Inc. |
proteína de fusão do fator viii compreendendo polipeptídeo do fator viii fusionado a polipeptí-deo recombinante estendido (xten) e seu método de fabricação, ácido nucleico, vetores, célula hospedeira, bem como composição farmacêutica e seu uso no tratamento de coagulopatia, episódio de hemorragia e hemofilia a
|
|
JP6383666B2
(ja)
|
2012-02-15 |
2018-08-29 |
バイオベラティブ セラピューティクス インコーポレイテッド |
組換え第viii因子タンパク質
|
|
HUE037720T2
(hu)
|
2012-03-28 |
2018-09-28 |
Sanofi Sa |
Bradikinin B1 receptor ligandumok elleni antitestek
|
|
US10114023B2
(en)
|
2012-04-18 |
2018-10-30 |
Massachusetts Institute Of Technology |
Method of enhancing the efficacy of anti-hepatocyte growth factor receptor breast cancer therapy by administering an inhibitor of menaINV
|
|
AU2013259786A1
(en)
|
2012-05-07 |
2014-11-20 |
Sanofi |
Methods for preventing biofilm formation
|
|
WO2013175276A1
(en)
|
2012-05-23 |
2013-11-28 |
Argen-X B.V |
Il-6 binding molecules
|
|
EP2859018B1
(en)
|
2012-06-06 |
2021-09-22 |
Zoetis Services LLC |
Caninized anti-ngf antibodies and methods thereof
|
|
WO2013185113A1
(en)
|
2012-06-08 |
2013-12-12 |
Biogen Idec Ma Inc. |
Procoagulant compounds
|
|
CN104427995A
(zh)
|
2012-06-08 |
2015-03-18 |
比奥根艾迪克Ma公司 |
嵌合凝血因子
|
|
EP2862875B1
(en)
|
2012-06-14 |
2023-09-06 |
Chugai Seiyaku Kabushiki Kaisha |
ANTIGEN-BINDING MOLECULE CONTAINING MODIFIED Fc REGION
|
|
RU2015101699A
(ru)
|
2012-06-21 |
2016-08-10 |
Индиана Юниверсити Рисерч Энд Текнолоджи Корпорейшн |
Слитые полипептиды и конъюгаты полипептида лиганда рецептора инкретина и fc-области с измененной fc-эффекторной функцией
|
|
US9499634B2
(en)
|
2012-06-25 |
2016-11-22 |
Zymeworks Inc. |
Process and methods for efficient manufacturing of highly pure asymmetric antibodies in mammalian cells
|
|
US20140004121A1
(en)
|
2012-06-27 |
2014-01-02 |
Amgen Inc. |
Anti-mesothelin binding proteins
|
|
EP2870250B2
(en)
|
2012-07-06 |
2022-06-29 |
Bioverativ Therapeutics Inc. |
Cell line expressing single chain factor viii polypeptides and uses thereof
|
|
EA201792485A3
(ru)
|
2012-07-11 |
2019-03-29 |
Амуникс Оперэйтинг Инк. |
Комплекс фактора viii с xten и белком-фактором фон виллебранда, и его применение (варианты)
|
|
WO2014009465A1
(en)
|
2012-07-13 |
2014-01-16 |
Roche Glycart Ag |
Bispecific anti-vegf/anti-ang-2 antibodies and their use in the treatment of ocular vascular diseases
|
|
EP3381943B1
(en)
|
2012-07-25 |
2022-03-16 |
Celldex Therapeutics, Inc. |
Anti-kit antibodies and uses thereof
|
|
US8603470B1
(en)
|
2012-08-07 |
2013-12-10 |
National Cheng Kung University |
Use of IL-20 antagonists for treating liver diseases
|
|
UA118251C2
(uk)
|
2012-08-23 |
2018-12-26 |
Ейдженсіс, Інк. |
Кон'югат антитіло-лікарський засіб (adc), який зв'язується з білком 158p1d7
|
|
TWI717591B
(zh)
|
2012-08-24 |
2021-02-01 |
日商中外製藥股份有限公司 |
FcγRIIb特異性Fc區域變異體
|
|
PE20150650A1
(es)
|
2012-09-12 |
2015-05-26 |
Genzyme Corp |
Polipeptidos que contienen fc con glicosilacion alterada y funcion efectora reducida
|
|
US9790268B2
(en)
|
2012-09-12 |
2017-10-17 |
Genzyme Corporation |
Fc containing polypeptides with altered glycosylation and reduced effector function
|
|
WO2014072876A1
(en)
|
2012-11-09 |
2014-05-15 |
Pfizer Inc. |
Platelet-derived growth factor b specific antibodies and compositions and uses thereof
|
|
US9914785B2
(en)
|
2012-11-28 |
2018-03-13 |
Zymeworks Inc. |
Engineered immunoglobulin heavy chain-light chain pairs and uses thereof
|
|
AU2013361275B2
(en)
|
2012-12-19 |
2016-11-24 |
Amplimmune, Inc. |
Anti-human B7-H4 antibodies and their uses
|
|
ES2949648T3
(es)
|
2012-12-20 |
2023-10-02 |
Purdue Research Foundation |
Células T que expresan un receptor antigénico quimérico como terapia contra el cáncer
|
|
JP6359031B2
(ja)
|
2012-12-21 |
2018-07-18 |
メディミューン,エルエルシー |
抗h7cr抗体
|
|
US9943610B2
(en)
|
2012-12-21 |
2018-04-17 |
Bioalliance C.V. |
Hydrophilic self-immolative linkers and conjugates thereof
|
|
JP6433297B2
(ja)
|
2012-12-27 |
2018-12-05 |
中外製薬株式会社 |
ヘテロ二量化ポリペプチド
|
|
TWI682941B
(zh)
|
2013-02-01 |
2020-01-21 |
美商再生元醫藥公司 |
含嵌合恆定區之抗體
|
|
EP2762496A1
(en)
|
2013-02-05 |
2014-08-06 |
EngMab AG |
Method for the selection of antibodies against BCMA
|
|
WO2014124006A1
(en)
|
2013-02-05 |
2014-08-14 |
The Johns Hopkins University |
Nanoparticles for magnetic resonance imaging tracking and methods of making and using thereof
|
|
EP2953972B1
(en)
|
2013-02-05 |
2020-07-08 |
EngMab Sàrl |
Method for the selection of antibodies against bcma
|
|
US10370431B2
(en)
|
2013-02-15 |
2019-08-06 |
Bioverativ Therapeutics Inc. |
Optimized factor VIII gene
|
|
US9487587B2
(en)
|
2013-03-05 |
2016-11-08 |
Macrogenics, Inc. |
Bispecific molecules that are immunoreactive with immune effector cells of a companion animal that express an activating receptor and cells that express B7-H3 and uses thereof
|
|
EP3424956A1
(en)
|
2013-03-11 |
2019-01-09 |
Genzyme Corporation |
Hyperglycosylated binding polypeptides
|
|
PT2968520T
(pt)
|
2013-03-14 |
2021-08-19 |
Macrogenics Inc |
Moléculas biespecíficas que são imunorreativas com células efetoras imunitárias que expressam um recetor de ativação
|
|
AR095527A1
(es)
|
2013-03-15 |
2015-10-21 |
Biogen Idec Inc |
Formulaciones de polipéptido fc-factor ix
|
|
WO2014144600A2
(en)
|
2013-03-15 |
2014-09-18 |
Viktor Roschke |
Multivalent and monovalent multispecific complexes and their uses
|
|
CN118406688A
(zh)
|
2013-03-15 |
2024-07-30 |
武田药品工业株式会社 |
抗血浆激肽释放酶抗体
|
|
TWI636062B
(zh)
|
2013-04-02 |
2018-09-21 |
中外製藥股份有限公司 |
Fc region variant
|
|
EP2983710B1
(en)
|
2013-04-09 |
2019-07-31 |
Annexon, Inc. |
Methods of treatment for neuromyelitis optica
|
|
EP2992331A4
(en)
|
2013-04-30 |
2017-03-29 |
Université de Montréal |
Novel biomarkers for acute myeloid leukemia
|
|
AU2014264295A1
(en)
|
2013-05-07 |
2015-10-29 |
Rinat Neuroscience Corp. |
Anti-glucagon receptor antibodies and methods of use thereof
|
|
KR20160129698A
(ko)
|
2013-05-24 |
2016-11-09 |
메디뮨 엘엘씨 |
항-b7-h5 항체 및 이의 용도
|
|
AU2014273817B2
(en)
|
2013-05-31 |
2019-03-14 |
Zymeworks Bc Inc. |
Heteromultimers with reduced or silenced effector function
|
|
WO2014200018A1
(ja)
|
2013-06-11 |
2014-12-18 |
独立行政法人 国立精神・神経医療研究センター |
再発寛解型多発性硬化症(rrms)患者の治療予後予測方法、及び新規治療適応判断方法
|
|
SG10202008809RA
(en)
|
2013-07-09 |
2020-10-29 |
Annexon Inc |
Anti-complement factor c1q antibodies and uses thereof
|
|
EP3027220A1
(en)
|
2013-08-01 |
2016-06-08 |
Agensys, Inc. |
Antibody drug conjugates (adc) that bind to cd37 proteins
|
|
CN113683695A
(zh)
|
2013-08-02 |
2021-11-23 |
辉瑞公司 |
抗cxcr4抗体及抗体-药物缀合物
|
|
EP3043813B1
(en)
|
2013-08-08 |
2021-01-13 |
Bioverativ Therapeutics Inc. |
Purification of chimeric fviii molecules
|
|
US11384149B2
(en)
|
2013-08-09 |
2022-07-12 |
Macrogenics, Inc. |
Bi-specific monovalent Fc diabodies that are capable of binding CD32B and CD79b and uses thereof
|
|
UA116479C2
(uk)
|
2013-08-09 |
2018-03-26 |
Макродженікс, Інк. |
БІСПЕЦИФІЧНЕ МОНОВАЛЕНТНЕ Fc-ДІАТІЛО, ЯКЕ ОДНОЧАСНО ЗВ'ЯЗУЄ CD32B I CD79b, ТА ЙОГО ЗАСТОСУВАННЯ
|
|
EP4707306A2
(en)
|
2013-08-13 |
2026-03-11 |
Sanofi |
Antibodies to plasminogen activator inhibitor-1 (pai-1) and uses thereof
|
|
TWI592426B
(zh)
|
2013-08-13 |
2017-07-21 |
賽諾菲公司 |
胞漿素原活化素抑制劑-1(pai-1)之抗體及其用途
|
|
WO2015023891A2
(en)
|
2013-08-14 |
2015-02-19 |
Biogen Idec Ma Inc. |
Factor viii-xten fusions and uses thereof
|
|
EP2839842A1
(en)
|
2013-08-23 |
2015-02-25 |
MacroGenics, Inc. |
Bi-specific monovalent diabodies that are capable of binding CD123 and CD3 and uses thereof
|
|
EP2840091A1
(en)
|
2013-08-23 |
2015-02-25 |
MacroGenics, Inc. |
Bi-specific diabodies that are capable of binding gpA33 and CD3 and uses thereof
|
|
DK3044234T3
(da)
|
2013-09-13 |
2020-05-18 |
Beigene Switzerland Gmbh |
Anti-PD1-antistoffer og anvendelse deraf som terapeutika og diagnostika
|
|
WO2015048330A2
(en)
|
2013-09-25 |
2015-04-02 |
Biogen Idec Ma Inc. |
On-column viral inactivation methods
|
|
AU2014325063B2
(en)
|
2013-09-27 |
2019-10-31 |
Chugai Seiyaku Kabushiki Kaisha |
Method for producing polypeptide heteromultimer
|
|
WO2015050959A1
(en)
|
2013-10-01 |
2015-04-09 |
Yale University |
Anti-kit antibodies and methods of use thereof
|
|
BR112016006999B1
(pt)
|
2013-10-02 |
2023-11-14 |
Medimmune, Llc |
Anticorpos neutralizantes antiinfluenza a seus usos, seu método de produção, composição que os compreendem, ácido nucleico e vetor
|
|
EP3063275B1
(en)
|
2013-10-31 |
2019-09-25 |
Resolve Therapeutics, LLC |
Therapeutic nuclease-albumin fusions and methods
|
|
US10584147B2
(en)
|
2013-11-08 |
2020-03-10 |
Biovertiv Therapeutics Inc. |
Procoagulant fusion compound
|
|
RU2708140C1
(ru)
|
2013-11-13 |
2019-12-04 |
Пфайзер Инк. |
Антитела, специфичные в отношении лиганда 1А, подобного фактору некроза опухолей, и их композиции и применения
|
|
HUE071428T2
(hu)
|
2013-11-27 |
2025-09-28 |
Zymeworks Bc Inc |
HER2-T célzó bispecifikus antigénkötõ-konstrukciók
|
|
WO2015087187A1
(en)
|
2013-12-10 |
2015-06-18 |
Rinat Neuroscience Corp. |
Anti-sclerostin antibodies
|
|
US8986691B1
(en)
|
2014-07-15 |
2015-03-24 |
Kymab Limited |
Method of treating atopic dermatitis or asthma using antibody to IL4RA
|
|
US8980273B1
(en)
|
2014-07-15 |
2015-03-17 |
Kymab Limited |
Method of treating atopic dermatitis or asthma using antibody to IL4RA
|
|
MX368804B
(es)
|
2013-12-24 |
2019-10-17 |
Univ Texas |
Antagonistas fcrn y metodos de uso.
|
|
EP3091997B1
(en)
|
2014-01-10 |
2022-07-06 |
Bioverativ Therapeutics Inc. |
Factor viii chimeric proteins and uses thereof
|
|
WO2015109212A1
(en)
|
2014-01-17 |
2015-07-23 |
Pfizer Inc. |
Anti-il-2 antibodies and compositions and uses thereof
|
|
TWI680138B
(zh)
|
2014-01-23 |
2019-12-21 |
美商再生元醫藥公司 |
抗pd-l1之人類抗體
|
|
TWI681969B
(zh)
|
2014-01-23 |
2020-01-11 |
美商再生元醫藥公司 |
針對pd-1的人類抗體
|
|
EP3104880B1
(en)
|
2014-02-14 |
2020-03-25 |
MacroGenics, Inc. |
Improved methods for the treatment of vascularizing cancers
|
|
TWI701042B
(zh)
|
2014-03-19 |
2020-08-11 |
美商再生元醫藥公司 |
用於腫瘤治療之方法及抗體組成物
|
|
HUE061339T2
(hu)
|
2014-03-19 |
2023-06-28 |
Genzyme Corp |
Targetáló csoportok helyspecifikus glikotechnikai átalakítása
|
|
US10556945B2
(en)
|
2014-03-21 |
2020-02-11 |
Teva Pharmaceuticals International Gmbh |
Antagonist antibodies directed against calcitonin gene-related peptide and methods using same
|
|
HUE065397T2
(hu)
|
2014-03-21 |
2024-06-28 |
Teva Pharmaceuticals Int Gmbh |
Kalcitonin génekkel kapcsolatos peptid elleni antagonista antitestek és azokat alkalmazó eljárások
|
|
KR102399028B1
(ko)
|
2014-03-21 |
2022-05-17 |
엑스-바디 인코포레이티드 |
이중-특이적 항원-결합 폴리펩티드
|
|
AU2015235967B2
(en)
|
2014-03-27 |
2020-10-22 |
Takeda Pharmaceutical Company Limited |
Compositions and methods for treatment of diabetic macular edema
|
|
PT3126391T
(pt)
*
|
2014-03-31 |
2019-11-27 |
Univ Hospital Of North Norway |
Anticorpos contra hpa-1a
|
|
KR102352573B1
(ko)
|
2014-04-04 |
2022-01-18 |
바이오노믹스 인코포레이티드 |
Lgr5에 결합하는 인간화된 항체들
|
|
SG11201607434WA
(en)
|
2014-04-07 |
2016-10-28 |
Chugai Pharmaceutical Co Ltd |
Immunoactivating antigen-binding molecule
|
|
LT3145530T
(lt)
|
2014-04-21 |
2021-07-12 |
D&D Pharmatech Inc. |
Trail receptoriaus agonistai, skirti fibrozinių ligų gydymui
|
|
WO2015164822A1
(en)
|
2014-04-25 |
2015-10-29 |
Purdue Research Foundation |
Collagen binding synthetic peptidoglycans for treatment of endothelial dysfunction
|
|
BR112016025291A2
(pt)
|
2014-04-30 |
2017-12-26 |
Abbvie Stemcentrx Llc |
conjugados de anticorpo anti-ptk7-fármaco
|
|
CA2947494C
(en)
|
2014-05-02 |
2020-10-20 |
Research Institute At Nationwide Children's Hospital |
Compositions and methods for anti-lyst immunomodulation
|
|
EA201692287A1
(ru)
|
2014-05-13 |
2017-06-30 |
Чугаи Сеияку Кабушики Каиша |
Антигенсвязывающая молекула, перенаправляющая т-клетки на клетки, обладающие иммуносупрессорной функцией
|
|
NZ726514A
(en)
|
2014-05-29 |
2019-01-25 |
Macrogenics Inc |
Tri-specific binding molecules and methods of use thereof
|
|
BR112016029860A2
(pt)
|
2014-06-20 |
2017-10-24 |
Abgenomics Int Inc |
conjugados de anticorpo antirreceptor alfa de folato (fra)-fármaco e métodos de uso dos mesmos
|
|
US11008561B2
(en)
|
2014-06-30 |
2021-05-18 |
Bioverativ Therapeutics Inc. |
Optimized factor IX gene
|
|
KR102130600B1
(ko)
|
2014-07-03 |
2020-07-08 |
베이진 엘티디 |
Pd-l1 항체와 이를 이용한 치료 및 진단
|
|
BR112017000640A2
(pt)
|
2014-07-15 |
2017-11-14 |
Lanzavecchia Antonio |
anticorpos neutralizantes do vírus influenza b e suas utilizações
|
|
SG10201900571YA
(en)
|
2014-07-22 |
2019-02-27 |
Cb Therapeutics Inc |
Anti-pd-1 antibodies
|
|
WO2016019126A1
(en)
|
2014-07-30 |
2016-02-04 |
The Research Foundation For The State University Of New York |
System and method for delivering genetic material or protein to cells
|
|
CN112999429B
(zh)
|
2014-08-01 |
2022-07-22 |
麻省理工学院 |
用于抗纤维化材料的修饰的藻酸盐以及应用
|
|
MX390385B
(es)
|
2014-08-05 |
2025-03-20 |
Cb Therapeutics Inc |
Anticuerpos anti-pd-l1.
|
|
JP2017523980A
(ja)
|
2014-08-06 |
2017-08-24 |
ライナット ニューロサイエンス コーポレイション |
Ldl−コレステロールを低下させるための方法
|
|
WO2016020799A1
(en)
|
2014-08-06 |
2016-02-11 |
Rinat Neuroscience Corp. |
Methods for reducing ldl-cholesterol
|
|
IL279606B
(en)
|
2014-08-08 |
2022-08-01 |
Alector Llc |
Anti-trem2 antibodies and methods of using them
|
|
WO2016034968A1
(en)
|
2014-09-02 |
2016-03-10 |
Pfizer Inc. |
Therapeutic antibody
|
|
WO2016036918A1
(en)
|
2014-09-03 |
2016-03-10 |
Boehringer Ingelheim International Gmbh |
Compound targeting il-23a and tnf-alpha and uses thereof
|
|
EP3197492A1
(en)
|
2014-09-23 |
2017-08-02 |
Pfizer Inc |
Treatment with anti-pcsk9 antibodies
|
|
EP3197481A1
(en)
|
2014-09-26 |
2017-08-02 |
Bayer Pharma Aktiengesellschaft |
Stabilized adrenomedullin derivatives and use thereof
|
|
MA40764A
(fr)
|
2014-09-26 |
2017-08-01 |
Chugai Pharmaceutical Co Ltd |
Agent thérapeutique induisant une cytotoxicité
|
|
CN107108721B
(zh)
|
2014-09-29 |
2021-09-07 |
杜克大学 |
包含hiv-1包膜靶向臂的双特异性分子
|
|
WO2016057769A2
(en)
|
2014-10-09 |
2016-04-14 |
Genzyme Corporation |
Glycoengineered antibody drug conjugates
|
|
EP3204417B1
(en)
|
2014-10-10 |
2020-07-22 |
Innate Pharma |
Cd73 blockade
|
|
EA201700181A1
(ru)
|
2014-10-14 |
2017-09-29 |
Галозим, Инк. |
Композиции аденозиндеаминазы-2 (ада-2), их варианты и способы использования
|
|
KR20170065662A
(ko)
|
2014-10-18 |
2017-06-13 |
화이자 인코포레이티드 |
항-il-7r 항체 조성물
|
|
SG10202008810QA
(en)
|
2014-11-05 |
2020-10-29 |
Annexon Inc |
Humanized anti-complement factor c1q antibodies and uses thereof
|
|
RS62003B2
(sr)
|
2014-11-10 |
2025-01-31 |
Medimmune Ltd |
Vezujući molekuli specifični za cd73 i njihove upotrebe
|
|
JP6847037B2
(ja)
|
2014-11-11 |
2021-03-24 |
メディミューン リミテッド |
抗cd73抗体とa2a受容体阻害薬とを含む併用治療薬及びその使用
|
|
ES2809455T3
(es)
|
2014-11-17 |
2021-03-04 |
Regeneron Pharma |
Métodos para tratamiento tumoral usando anticuerpo biespecífico CD3xCD20
|
|
CN113929770A
(zh)
|
2014-11-21 |
2022-01-14 |
百时美施贵宝公司 |
包含修饰的重链恒定区的抗体
|
|
KR102569813B1
(ko)
|
2014-11-21 |
2023-08-24 |
브리스톨-마이어스 스큅 컴퍼니 |
Cd73에 대항한 항체 및 그의 용도
|
|
TWI595006B
(zh)
|
2014-12-09 |
2017-08-11 |
禮納特神經系統科學公司 |
抗pd-1抗體類和使用彼等之方法
|
|
WO2016098356A1
(en)
|
2014-12-19 |
2016-06-23 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-c5 antibodies and methods of use
|
|
KR102650420B1
(ko)
|
2014-12-19 |
2024-03-21 |
추가이 세이야쿠 가부시키가이샤 |
항-마이오스타틴 항체, 변이체 Fc 영역을 함유하는 폴리펩타이드, 및 사용 방법
|
|
EA039219B1
(ru)
|
2014-12-23 |
2021-12-20 |
Бристол-Майерс Сквибб Компани |
Антитела к tigit
|
|
WO2016103093A1
(en)
|
2014-12-23 |
2016-06-30 |
Pfizer Inc. |
Stable aqueous antibody formulation for anti tnf alpha antibodies
|
|
TWI688572B
(zh)
|
2015-01-26 |
2020-03-21 |
美商宏觀基因股份有限公司 |
包含dr5-結合結構域的多價分子
|
|
WO2016123125A1
(en)
|
2015-01-27 |
2016-08-04 |
The Johns Hopkins University |
Hypotonic hydrogel formulations for enhanced transport of active agents at mucosal surfaces
|
|
CN107206080B
(zh)
|
2015-01-28 |
2022-07-08 |
辉瑞公司 |
稳定的水性抗血管内皮细胞生长因子(vegf)抗体制剂
|
|
CN112142844B
(zh)
|
2015-02-05 |
2025-07-25 |
中外制药株式会社 |
包含离子浓度依赖性的抗原结合结构域的抗体,fc区变体,il-8-结合抗体及其应用
|
|
TWI805046B
(zh)
|
2015-02-27 |
2023-06-11 |
日商中外製藥股份有限公司 |
Il-6受體抗體用於製備醫藥組成物的用途
|
|
MY188761A
(en)
|
2015-03-09 |
2021-12-29 |
Argenx Bvba |
Method of reducing serum levels of fc-containing agents using fcrn antagonists
|
|
CA2980748A1
(en)
|
2015-03-25 |
2016-09-29 |
Children's Hospital Medical Center |
Use of kit inhibitors to condition subjects for a hematopoietic stem cell (hsc) transplantation
|
|
EP3277725B1
(en)
|
2015-03-30 |
2020-11-25 |
Regeneron Pharmaceuticals, Inc. |
Heavy chain constant regions with reduced binding to fc gamma receptors
|
|
JP7082484B2
(ja)
|
2015-04-01 |
2022-06-08 |
中外製薬株式会社 |
ポリペプチド異種多量体の製造方法
|
|
SI3280441T1
(sl)
|
2015-04-07 |
2022-01-31 |
Alector Llc |
Protitelesa anti-sortilin in metoda njihove uporabe
|
|
PT3283106T
(pt)
|
2015-04-13 |
2022-02-02 |
Pfizer |
Anticorpos terapêuticos e as suas utilizações
|
|
KR102208443B1
(ko)
|
2015-04-13 |
2021-01-27 |
화이자 인코포레이티드 |
B-세포 성숙 항원을 표적화하는 키메라 항원 수용체
|
|
WO2016187356A1
(en)
|
2015-05-18 |
2016-11-24 |
Agensys, Inc. |
Antibodies that bind to axl proteins
|
|
WO2016187354A1
(en)
|
2015-05-18 |
2016-11-24 |
Agensys, Inc. |
Antibodies that bind to axl proteins
|
|
WO2016186154A1
(ja)
|
2015-05-19 |
2016-11-24 |
国立研究開発法人国立精神・神経医療研究センター |
多発性硬化症(ms)患者の新規治療適用判断方法
|
|
JP6797137B2
(ja)
|
2015-05-29 |
2020-12-09 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
Ox40に対する抗体およびその使用
|
|
TWI773646B
(zh)
|
2015-06-08 |
2022-08-11 |
美商宏觀基因股份有限公司 |
結合lag-3的分子和其使用方法
|
|
WO2016201388A2
(en)
|
2015-06-12 |
2016-12-15 |
Alector Llc |
Anti-cd33 antibodies and methods of use thereof
|
|
TWI870335B
(zh)
|
2015-06-12 |
2025-01-21 |
美商宏觀基因股份有限公司 |
變異的嵌合4d5抗體及其與抗pd-1抗體聯合用於治療癌症的應用
|
|
EP3307779A2
(en)
|
2015-06-12 |
2018-04-18 |
Alector LLC |
Anti-cd33 antibodies and methods of use thereof
|
|
CN115505042A
(zh)
|
2015-06-26 |
2022-12-23 |
赛诺菲生物技术公司 |
单克隆抗il-1racp抗体
|
|
US10877045B2
(en)
|
2015-07-21 |
2020-12-29 |
Saint Louis University |
Compositions and methods for diagnosing and treating endometriosis-related infertility
|
|
KR20250054123A
(ko)
|
2015-07-21 |
2025-04-22 |
다케다 파머수티컬 컴패니 리미티드 |
Xiia 인자의 단일클론 항체 저해제
|
|
WO2017015619A1
(en)
|
2015-07-23 |
2017-01-26 |
The Regents Of The University Of California |
Antibodies to coagulation factor xia and uses thereof
|
|
EP3328427B1
(en)
|
2015-07-27 |
2024-05-29 |
The General Hospital Corporation |
Antibody derivatives with conditionally enabled effector function
|
|
MA58293B1
(fr)
|
2015-07-30 |
2024-11-29 |
Macrogenics, Inc. |
Molécules de liaison pd-1 et leurs procédés d'utilisation
|
|
EP3331910B1
(en)
|
2015-08-03 |
2019-12-11 |
EngMab Sàrl |
Monoclonal antibodies against human b cell maturation antigen (bcma)
|
|
EA201890423A1
(ru)
|
2015-08-03 |
2018-07-31 |
Биовератив Терапьютикс Инк. |
Слитые белки фактора ix, способы их получения и применения
|
|
KR20180054639A
(ko)
|
2015-08-28 |
2018-05-24 |
알렉터 엘엘씨 |
항-siglec-7 항체 및 이의 사용 방법
|
|
PL3344654T3
(pl)
|
2015-09-02 |
2021-05-17 |
Immutep S.A.S. |
Przeciwciała anty-lag-3
|
|
WO2017046746A1
(en)
|
2015-09-15 |
2017-03-23 |
Acerta Pharma B.V. |
Therapeutic combinations of a btk inhibitor and a gitr binding molecule, a 4-1bb agonist, or an ox40 agonist
|
|
LT3353212T
(lt)
|
2015-09-23 |
2021-12-27 |
Regeneron Pharmaceuticals, Inc. |
Optimizuoti anti-cd3 bispecifiniai antikūnai ir jų naudojimas
|
|
WO2017058944A1
(en)
|
2015-09-29 |
2017-04-06 |
Amgen Inc. |
Asgr inhibitors
|
|
WO2017055966A1
(en)
|
2015-10-01 |
2017-04-06 |
Pfizer Inc. |
Low viscosity antibody compositions
|
|
WO2017062672A2
(en)
|
2015-10-06 |
2017-04-13 |
Alector Llc |
Anti-trem2 antibodies and methods of use thereof
|
|
US11130817B2
(en)
|
2015-10-12 |
2021-09-28 |
Innate Pharma |
CD73 blocking agents
|
|
US10138298B2
(en)
|
2015-10-23 |
2018-11-27 |
The Regents Of The University Of California |
Anti-IL-2 antibodies and compositions and uses thereof
|
|
WO2017075432A2
(en)
|
2015-10-29 |
2017-05-04 |
Alector Llc |
Anti-siglec-9 antibodies and methods of use thereof
|
|
ES2978718T3
(es)
|
2015-11-01 |
2024-09-18 |
Massachusetts Inst Technology |
Alginatos modificados para materiales antifibróticos y aplicaciones
|
|
AU2016344041B2
(en)
|
2015-11-01 |
2019-11-07 |
Massachusetts Institute Of Technology |
Materials with improved properties
|
|
US11649293B2
(en)
|
2015-11-18 |
2023-05-16 |
Chugai Seiyaku Kabushiki Kaisha |
Method for enhancing humoral immune response
|
|
US11660340B2
(en)
|
2015-11-18 |
2023-05-30 |
Chugai Seiyaku Kabushiki Kaisha |
Combination therapy using T cell redirection antigen binding molecule against cell having immunosuppressing function
|
|
PT3383920T
(pt)
|
2015-11-30 |
2024-04-15 |
Univ California |
Entrega de carga útil específica para tumores e ativação imune utilizando um anticorpo humano que tem como alvo um antigénio altamente específico da superfície das células tumorais
|
|
EP3383908A1
(en)
|
2015-12-02 |
2018-10-10 |
Stsciences, Inc. |
Antibodies specific to glycosylated btla (b- and t- lymphocyte attenuator)
|
|
WO2017096051A1
(en)
|
2015-12-02 |
2017-06-08 |
Stcube & Co., Inc. |
Antibodies and molecules that immunospecifically bind to btn1a1 and the therapeutic uses thereof
|
|
CN108367069B
(zh)
|
2015-12-14 |
2022-08-23 |
宏观基因有限公司 |
对于pd-1和ctla-4具有免疫反应性的双特异性分子及其使用方法
|
|
DK3389696T3
(da)
|
2015-12-17 |
2024-12-16 |
Univ Johns Hopkins |
Ameliorating systemic sclerosis with death receptor agonists
|
|
LT3394103T
(lt)
|
2015-12-22 |
2023-09-11 |
Regeneron Pharmaceuticals, Inc. |
Antikūnų prieš pd-1 ir bispecifinių antikūnų prieš cd20/cd3 derinys, skirtas vėžiui gydyti
|
|
US11359009B2
(en)
|
2015-12-25 |
2022-06-14 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-myostatin antibodies and methods of use
|
|
AU2016381992B2
(en)
|
2015-12-28 |
2024-01-04 |
Chugai Seiyaku Kabushiki Kaisha |
Method for promoting efficiency of purification of Fc region-containing polypeptide
|
|
US10472422B2
(en)
|
2016-01-08 |
2019-11-12 |
Abgenomics International Inc. |
Tetravalent anti-PSGL-1 antibodies and uses thereof
|
|
JP2019506398A
(ja)
|
2016-01-21 |
2019-03-07 |
ファイザー・インク |
上皮増殖因子受容体変異体iiiおよびcd3の単一および二重特異性抗体およびそれらの使用
|
|
BR112018014585A2
(pt)
|
2016-01-21 |
2018-12-11 |
Pfizer |
receptores de antígeno quiméricos que direcionam o receptor do fator de crescimento epidérmico variante iii
|
|
EP3411478B1
(en)
|
2016-02-01 |
2022-06-08 |
Bioverativ Therapeutics Inc. |
Optimized factor viii genes
|
|
US20190284293A1
(en)
|
2016-03-04 |
2019-09-19 |
Bristol-Myers Squibb Company |
Combination therapy with anti-cd73 antibodies
|
|
US11472877B2
(en)
|
2016-03-04 |
2022-10-18 |
Alector Llc |
Anti-TREM1 antibodies and methods of use thereof
|
|
US10443054B2
(en)
|
2016-03-06 |
2019-10-15 |
Massachusetts Institute Of Technology |
Methods for identifying and treating invasive/metastatic breast cancers
|
|
CN109071614B
(zh)
|
2016-03-08 |
2022-09-06 |
碁米库斯生物科技股份有限公司 |
肺炎球菌溶血素ply截短胜肽及其用途
|
|
KR20180116215A
(ko)
|
2016-03-14 |
2018-10-24 |
추가이 세이야쿠 가부시키가이샤 |
암의 치료에 이용하기 위한 세포상해 유도 치료제
|
|
US20190071514A1
(en)
|
2016-03-14 |
2019-03-07 |
Innate Pharma |
Anti-cd39 antibodies
|
|
JP2019517993A
(ja)
|
2016-03-15 |
2019-06-27 |
イナート・ファルマ・ソシエテ・アノニムInnate Pharma Pharma S.A. |
抗mica抗体
|
|
AU2017239038B2
(en)
|
2016-03-22 |
2024-06-27 |
Bionomics Inc |
Administration of an anti-LGR5 monoclonal antibody
|
|
KR102508650B1
(ko)
|
2016-04-07 |
2023-03-13 |
더 존스 홉킨스 유니버시티 |
사멸 수용체 작용제로써 췌장암 및 통증을 치료하기 위한 조성물 및 방법
|
|
JP7282521B2
(ja)
|
2016-04-08 |
2023-05-29 |
パーデュー・リサーチ・ファウンデイション |
Car t細胞療法のための方法および組成物
|
|
PE20190353A1
(es)
|
2016-04-15 |
2019-03-07 |
Macrogenics Inc |
Moleculas de union b7-h3 novedosas, conjugados anticuerpo-farmaco de los mismos y metodos de uso de los mismos
|
|
CA3019398A1
(en)
|
2016-04-26 |
2017-11-02 |
R.P. Scherer Technologies, Llc |
Antibody conjugates and methods of making and using the same
|
|
EP3448997B1
(en)
|
2016-04-27 |
2020-10-14 |
Massachusetts Institute of Technology |
Stable nanoscale nucleic acid assemblies and methods thereof
|
|
WO2017189914A1
(en)
|
2016-04-27 |
2017-11-02 |
Massachusetts Institute Of Technology |
Sequence-controlled polymer random access memory storage
|
|
CR20180554A
(es)
|
2016-04-28 |
2019-01-10 |
Chugai Pharmaceutical Co Ltd |
Preparaciones que contienen anticuerpos
|
|
US10968279B2
(en)
|
2016-05-09 |
2021-04-06 |
Bristol-Myers Squibb Company |
TL1A antibodies and uses thereof
|
|
TWI755395B
(zh)
|
2016-05-13 |
2022-02-21 |
美商再生元醫藥公司 |
抗-pd-1抗體與輻射治療癌症之組合
|
|
WO2017201731A1
(en)
|
2016-05-27 |
2017-11-30 |
Beijing Vdjbio Co., Ltd. |
Antibodies, composition and kits comprising same, and methods of use thereof
|
|
CA3029627A1
(en)
|
2016-07-01 |
2018-01-04 |
Resolve Therapeutics, Llc |
Optimized binuclease fusions and methods
|
|
WO2018007885A1
(en)
|
2016-07-05 |
2018-01-11 |
Beigene, Ltd. |
COMBINATION OF A PD-l ANTAGONIST AND A RAF INHIBITOR FOR TREATING CANCER
|
|
EP3487521A4
(en)
|
2016-07-21 |
2020-07-01 |
Emory University |
ANTIBODIES AGAINST EBOLA VIRUS AND LIAISON AGENTS DERIVED THEREFROM
|
|
KR20230107408A
(ko)
|
2016-07-29 |
2023-07-14 |
주노 쎄러퓨티크스 인코퍼레이티드 |
항-cd19 항체에 대한 항-이디오타입 항체
|
|
CA3032305A1
(en)
|
2016-07-29 |
2018-02-01 |
New York University |
Treating solid tumor by targeting dectin-1 signaling
|
|
KR20190044070A
(ko)
|
2016-08-03 |
2019-04-29 |
넥스트큐어 인코포레이티드 |
Lair 신호 변환을 조정하기 위한 조성물 및 방법
|
|
MX2019001448A
(es)
|
2016-08-05 |
2019-09-13 |
Chugai Pharmaceutical Co Ltd |
Composicion para profilaxis o tratamiento de enfermedades relacionadas con interleucina 8 (il-8).
|
|
JP7161266B2
(ja)
|
2016-08-05 |
2022-10-26 |
メディミューン,エルエルシー |
抗o2抗体およびその使用
|
|
WO2018033135A1
(en)
|
2016-08-19 |
2018-02-22 |
Beigene, Ltd. |
Use of a combination comprising a btk inhibitor for treating cancers
|
|
WO2018053032A1
(en)
|
2016-09-13 |
2018-03-22 |
Humanigen, Inc. |
Epha3 antibodies for the treatment of pulmonary fibrosis
|
|
SG10201607778XA
(en)
|
2016-09-16 |
2018-04-27 |
Chugai Pharmaceutical Co Ltd |
Anti-Dengue Virus Antibodies, Polypeptides Containing Variant Fc Regions, And Methods Of Use
|
|
WO2018057735A1
(en)
|
2016-09-21 |
2018-03-29 |
Nextcure, Inc. |
Antibodies for siglec-15 and methods of use thereof
|
|
EP4360714A3
(en)
|
2016-09-21 |
2024-07-24 |
Nextcure, Inc. |
Antibodies for siglec-15 and methods of use thereof
|
|
WO2018055574A1
(en)
|
2016-09-23 |
2018-03-29 |
Teva Pharmaceuticals International Gmbh |
Treating refractory migraine
|
|
AU2017331592A1
(en)
|
2016-09-23 |
2019-04-11 |
Teva Pharmaceuticals International Gmbh |
Treating cluster headache
|
|
WO2018065552A1
(en)
|
2016-10-06 |
2018-04-12 |
Innate Pharma |
Anti-cd39 antibodies
|
|
AU2017345479B2
(en)
|
2016-10-19 |
2024-03-21 |
The Scripps Research Institute |
Chimeric antigen receptor effector cell switches with humanized targeting moieties and/or optimized chimeric antigen receptor interacting domains and uses thereof
|
|
AU2017346488A1
(en)
|
2016-10-19 |
2019-05-30 |
Humabs Biomed Sa |
Anti-O1 antibodies and uses thereof
|
|
TWI788307B
(zh)
|
2016-10-31 |
2023-01-01 |
美商艾歐凡斯生物治療公司 |
用於擴增腫瘤浸潤性淋巴細胞之工程化人造抗原呈現細胞
|
|
KR102687833B1
(ko)
|
2016-11-02 |
2024-07-24 |
브리스톨-마이어스 스큅 컴퍼니 |
다발성 골수종 치료를 위한 bcma 및 cd3에 대응하는 이중 특이적 항체 및 면역학적 약물의 복합용도
|
|
JOP20190100A1
(ar)
|
2016-11-19 |
2019-05-01 |
Potenza Therapeutics Inc |
بروتينات ربط مولد ضد مضاد لـ gitr وطرق استخدامها
|
|
KR20260008164A
(ko)
|
2016-12-02 |
2026-01-15 |
바이오버라티브 테라퓨틱스 인크. |
키메라 응고 인자를 사용해 혈우병성 관절증을 치료하는 방법
|
|
EP3548063A1
(en)
|
2016-12-02 |
2019-10-09 |
Bioverativ Therapeutics Inc. |
Methods of inducing immune tolerance to clotting factors
|
|
JP7173971B2
(ja)
|
2016-12-09 |
2022-11-16 |
アレクトル エルエルシー |
抗SIRP-α抗体及びその使用方法
|
|
JOP20190134A1
(ar)
|
2016-12-23 |
2019-06-02 |
Potenza Therapeutics Inc |
بروتينات رابطة لمولد ضد مضادة لنيوروبيلين وطرق استخدامها
|
|
TW201825515A
(zh)
|
2017-01-04 |
2018-07-16 |
美商伊繆諾金公司 |
Met抗體以及其免疫結合物及用途
|
|
ES3055314T3
(en)
|
2017-01-06 |
2026-02-11 |
Iovance Biotherapeutics Inc |
Expansion of tumor infiltrating lymphocytes with potassium channel agonists and therapeutic uses thereof
|
|
TWI902654B
(zh)
|
2017-01-06 |
2025-11-01 |
美商艾歐凡斯生物治療公司 |
以腫瘤壞死因子受體超家族(tnfrsf)促效劑使腫瘤浸潤淋巴球(til)擴增及til與tnfrsf促效劑的治療組合
|
|
EP3573989A4
(en)
|
2017-01-25 |
2020-11-18 |
Beigene, Ltd. |
CRYSTALLINE FORMS OF (S) -7- (1- (BUT-2-YNOYL) PIPERIDIN-4-YL) -2- (4-PHENOXYPHENYL) -4, 5, 6, 7-TETRAHY DROPYRAZOLO [1, 5-A ] PYRIMIDINE-3-CARBOXAMIDE, PREPARATION AND ASSOCIATED USES
|
|
CN110582288B
(zh)
|
2017-02-28 |
2024-09-20 |
恩多塞特公司 |
用于car t细胞疗法的组合物和方法
|
|
CA3055195A1
(en)
|
2017-03-02 |
2018-09-07 |
Beth Israel Deaconess Medical Center, Inc. |
Selecting headache patients responsive to antibodies directed against calcitonin gene related peptide
|
|
BR112019017500A2
(pt)
|
2017-03-03 |
2020-04-14 |
Rinat Neuroscience Corp |
anticorpos anti-gitr e métodos de uso dos mesmos
|
|
KR102584011B1
(ko)
|
2017-03-16 |
2023-09-27 |
이나뜨 파르마 에스.에이. |
암 치료를 위한 조성물 및 방법
|
|
JOP20190203A1
(ar)
|
2017-03-30 |
2019-09-03 |
Potenza Therapeutics Inc |
بروتينات رابطة لمولد ضد مضادة لـ tigit وطرق استخدامها
|
|
US11603407B2
(en)
|
2017-04-06 |
2023-03-14 |
Regeneron Pharmaceuticals, Inc. |
Stable antibody formulation
|
|
WO2018185284A1
(en)
|
2017-04-07 |
2018-10-11 |
Miltenyi Biotec Gmbh |
POLYPEPTIDES WITH MUTANT HUMAN IgG4
|
|
US20230192839A1
(en)
|
2017-04-12 |
2023-06-22 |
Pfizer Inc. |
Antibodies having conditional affinity and methods of use thereof
|
|
US10993936B2
(en)
|
2017-04-14 |
2021-05-04 |
Arizona Board Of Regents On Behalf Of The University Of Arizona |
Method of treating one or more symptoms of pulmonary fibrosis by administering inhibitors of nicotinamide phosphoribotransferase
|
|
US11279755B2
(en)
|
2017-04-25 |
2022-03-22 |
Lbl Biotechnology, Inc. |
Use of IL-20 antagonists for treating eye diseases
|
|
EP3620531A4
(en)
|
2017-05-02 |
2021-03-17 |
National Center of Neurology and Psychiatry |
METHOD OF PREDICTION AND EVALUATION OF THERAPEUTIC EFFECT IN DISEASES RELATING TO IL-6 AND NEUTROPHILS
|
|
MX2019013202A
(es)
|
2017-05-10 |
2020-01-21 |
Iovance Biotherapeutics Inc |
Expansion de linfocitos de infiltracion de tumor a partir de tumores liquidos y usos terapeuticos de los mismos.
|
|
WO2018213316A1
(en)
|
2017-05-16 |
2018-11-22 |
Alector Llc |
Anti-siglec-5 antibodies and methods of use thereof
|
|
BR112019024419A2
(pt)
|
2017-05-25 |
2020-07-14 |
Bristol-Myers Squibb Company |
anticorpos compreendendo regiões constantes pesadas modificadas
|
|
WO2018222685A1
(en)
|
2017-05-31 |
2018-12-06 |
Stcube & Co., Inc. |
Methods of treating cancer using antibodies and molecules that immunospecifically bind to btn1a1
|
|
CA3065301A1
(en)
|
2017-05-31 |
2018-12-06 |
Stcube & Co., Inc. |
Antibodies and molecules that immunospecifically bind to btn1a1 and the therapeutic uses thereof
|
|
BR112019025243A2
(pt)
|
2017-06-02 |
2020-07-14 |
Pfizer Inc. |
anticorpos específicos para flt3 e usos dos mesmos
|
|
CA3062328A1
(en)
|
2017-06-02 |
2018-12-06 |
Pfizer Inc. |
Chimeric antigen receptors targeting flt3
|
|
AU2018281337B2
(en)
|
2017-06-06 |
2022-08-25 |
Relinia, Inc. |
Single-chain TNF receptor 2 agonist fusion proteins
|
|
WO2018226671A1
(en)
|
2017-06-06 |
2018-12-13 |
Stcube & Co., Inc. |
Methods of treating cancer using antibodies and molecules that bind to btn1a1 or btn1a1-ligands
|
|
WO2018236889A2
(en)
|
2017-06-19 |
2018-12-27 |
Massachusetts Institute Of Technology |
Automated methods for scalable, parallelized enzymatic biopolymer synthesis and modification using microfluidic devices
|
|
WO2019001417A1
(en)
|
2017-06-26 |
2019-01-03 |
Beigene, Ltd. |
IMMUNOTHERAPY FOR HEPATOCELLULAR CARCINOMA
|
|
KR20200026263A
(ko)
|
2017-07-07 |
2020-03-10 |
시믹 아이피, 엘엘씨 |
합성 생체접합체
|
|
BR112020000679A2
(pt)
|
2017-07-13 |
2020-07-14 |
Massachusetts Institute Of Technology |
visando o complexo hdac2-sp3 para potencializar a função sináptica
|
|
US20190016804A1
(en)
|
2017-07-14 |
2019-01-17 |
Immatics Biotechnologies Gmbh |
Dual specificity polypeptide molecule
|
|
DE102017115966A1
(de)
|
2017-07-14 |
2019-01-17 |
Immatics Biotechnologies Gmbh |
Polypeptidmolekül mit verbesserter zweifacher Spezifität
|
|
US20190048073A1
(en)
|
2017-07-20 |
2019-02-14 |
Pfizer Inc. |
Anti-gd3 antibodies and antibody-drug conjugates
|
|
WO2019016784A1
(en)
|
2017-07-21 |
2019-01-24 |
Universidade De Coimbra |
ANTI-NUCLEOLIN ANTIBODIES
|
|
US10961318B2
(en)
|
2017-07-26 |
2021-03-30 |
Forty Seven, Inc. |
Anti-SIRP-α antibodies and related methods
|
|
TW202511296A
(zh)
|
2017-08-03 |
2025-03-16 |
美商阿列克特有限責任公司 |
抗trem2抗體及其使用方法
|
|
AU2018310985A1
(en)
|
2017-08-03 |
2019-11-07 |
Alector Llc |
Anti-CD33 antibodies and methods of use thereof
|
|
JP7374883B2
(ja)
|
2017-08-09 |
2023-11-07 |
バイオベラティブ セラピューティクス インコーポレイテッド |
核酸分子およびその使用
|
|
BR112020003670A2
(pt)
|
2017-08-22 |
2020-09-01 |
Sanabio, Llc |
receptores de interferon solúveis e usos dos mesmos
|
|
CN118909118A
(zh)
|
2017-09-07 |
2024-11-08 |
奥古斯塔大学研究所公司 |
程序性细胞死亡蛋白1抗体
|
|
KR102771895B1
(ko)
|
2017-10-20 |
2025-02-21 |
가꼬우호우징 효고 이카다이가쿠 |
항il-6 수용체 항체를 함유하는 수술 후의 유착을 억제하기 위한 의약 조성물
|
|
SG11202003246WA
(en)
|
2017-10-27 |
2020-05-28 |
Pfizer |
Antibodies and antibody-drug conjugates specific for cd123 and uses thereof
|
|
SG11202003652QA
(en)
|
2017-10-27 |
2020-05-28 |
Univ New York |
Anti-galectin-9 antibodies and uses thereof
|
|
CN119161488A
(zh)
|
2017-11-01 |
2024-12-20 |
中外制药株式会社 |
具有降低的生物活性的抗体变体和同种型
|
|
US10940171B2
(en)
|
2017-11-10 |
2021-03-09 |
Massachusetts Institute Of Technology |
Microbial production of pure single stranded nucleic acids
|
|
EP3710589A4
(en)
|
2017-11-14 |
2021-11-10 |
Chugai Seiyaku Kabushiki Kaisha |
ANTI-C1S ANTIBODIES AND METHOD OF USING
|
|
CA3083118A1
(en)
|
2017-11-22 |
2019-05-31 |
Iovance Biotherapeutics, Inc. |
Expansion of peripheral blood lymphocytes (pbls) from peripheral blood
|
|
CN111801334B
(zh)
|
2017-11-29 |
2023-06-09 |
百济神州瑞士有限责任公司 |
使用包含btk抑制剂的组合治疗惰性或侵袭性b-细胞淋巴瘤
|
|
WO2019110823A1
(en)
|
2017-12-08 |
2019-06-13 |
Argenx Bvba |
Use of fcrn antagonists for treatment of generalized myasthenia gravis
|
|
US20210369775A1
(en)
|
2017-12-15 |
2021-12-02 |
Iovance Biotherapeutics, Inc. |
Systems and methods for determining the beneficial administration of tumor infiltrating lymphocytes, and methods of use thereof and beneficial administration of tumor infiltrating lymphocytes, and methods of use thereof
|
|
JP7490565B2
(ja)
|
2017-12-29 |
2024-05-27 |
アレクトル エルエルシー |
抗tmem106b抗体及びその使用方法
|
|
MX2020007077A
(es)
|
2018-01-04 |
2020-10-28 |
Iconic Therapeutics Inc |
Anticuerpos anti-factor tisular, conjugados anticuerpo-farmaco y metodos relacionados.
|
|
EP3735270A1
(en)
|
2018-01-05 |
2020-11-11 |
Modernatx, Inc. |
Polynucleotides encoding anti-chikungunya virus antibodies
|
|
EP3740282B1
(en)
|
2018-01-17 |
2025-03-26 |
University of Connecticut |
Metallothionein inhibitors for treating diabetes, hepatitis, and/or inflammatory liver disease
|
|
CN120154716A
(zh)
|
2018-01-22 |
2025-06-17 |
恩多塞特公司 |
Car t细胞的使用方法
|
|
CN112566934B
(zh)
|
2018-01-23 |
2024-09-17 |
奈斯科尔公司 |
B7-h4抗体及其使用方法
|
|
US11472874B2
(en)
|
2018-01-31 |
2022-10-18 |
Alector Llc |
Anti-MS4A4A antibodies and methods of use thereof
|
|
KR20200118089A
(ko)
|
2018-02-01 |
2020-10-14 |
바이오버라티브 테라퓨틱스 인크. |
인자 viii을 발현하는 렌티바이러스 벡터의 용도
|
|
WO2019152705A1
(en)
|
2018-02-01 |
2019-08-08 |
Pfizer Inc. |
Antibodies specific for cd70 and their uses
|
|
EP3746483A1
(en)
|
2018-02-01 |
2020-12-09 |
Pfizer Inc |
Chimeric antigen receptors targeting cd70
|
|
JP2021512962A
(ja)
|
2018-02-13 |
2021-05-20 |
アイオバンス バイオセラピューティクス,インコーポレイテッド |
アデノシンa2a受容体アンタゴニストによる腫瘍浸潤性リンパ球(til)の拡大培養並びにtil及びアデノシンa2a受容体アンタゴニストの治療的組み合わせ
|
|
CN112105382A
(zh)
|
2018-02-23 |
2020-12-18 |
恩多塞特公司 |
用于car t细胞疗法的顺序方法
|
|
CN112513070A
(zh)
|
2018-02-28 |
2021-03-16 |
辉瑞公司 |
Il-15变体及其用途
|
|
US20210002373A1
(en)
|
2018-03-01 |
2021-01-07 |
Nextcure, Inc. |
KLRG1 Binding Compositions and Methods of Use Thereof
|
|
CA3093772C
(en)
|
2018-03-12 |
2024-04-16 |
Zoetis Services Llc |
Anti-ngf antibodies and methods thereof
|
|
CN116327926A
(zh)
|
2018-03-15 |
2023-06-27 |
中外制药株式会社 |
对寨卡病毒具有交叉反应性的抗登革热病毒抗体及使用方法
|
|
MX2020009975A
(es)
|
2018-03-28 |
2020-10-12 |
Bristol Myers Squibb Co |
Proteinas de fusion interleucina-2/receptor alfa de interleucina-2 y metodos de uso.
|
|
MA52630B1
(fr)
|
2018-05-18 |
2025-07-31 |
Bioverativ Therapeutics Inc. |
Procédés de traitement de l'hémophilie a
|
|
CA3100829A1
(en)
|
2018-05-23 |
2019-11-28 |
Pfizer Inc. |
Antibodies specific for gucy2c and uses thereof
|
|
ES2984950T3
(es)
|
2018-05-23 |
2024-10-31 |
Pfizer |
Anticuerpos específicos para CD3 y sus usos
|
|
US11319373B2
(en)
|
2018-05-25 |
2022-05-03 |
Alector Llc |
Anti-SIRPA antibodies and methods of use thereof
|
|
WO2019236417A1
(en)
|
2018-06-04 |
2019-12-12 |
Biogen Ma Inc. |
Anti-vla-4 antibodies having reduced effector function
|
|
JP7543144B2
(ja)
|
2018-06-05 |
2024-09-02 |
アムジエン・インコーポレーテツド |
抗体依存性細胞貪食の調節
|
|
EP3801767A1
(en)
|
2018-06-08 |
2021-04-14 |
Alector LLC |
Anti-siglec-7 antibodies and methods of use thereof
|
|
US20210196823A1
(en)
|
2018-06-08 |
2021-07-01 |
Pfizer Inc. |
Methods of Treating Metabolic Disease
|
|
JP7486437B2
(ja)
|
2018-06-08 |
2024-05-17 |
アルジェニクス ビーブイ |
免疫性血小板減少症を治療する組成物及び方法
|
|
BR112020024412A8
(pt)
|
2018-06-18 |
2023-03-21 |
Innate Pharma |
Anticorpos, composição farmacêutica, kit, ácido nucleico, célula hospedeira, métodos de tratamento ou prevenção de câncer, de redução da atividade, de aumento da atividade e de aumento da ativação
|
|
MX2020013324A
(es)
|
2018-06-29 |
2021-05-12 |
Alector Llc |
Anticuerpos anti proteína reguladora de señales beta 1 (sirp-beta1) y métodos de uso de los mismos.
|
|
MX2021000016A
(es)
|
2018-07-03 |
2021-03-09 |
Bristol Myers Squibb Co |
Formulaciones de factor de crecimiento de fibroblastos (fgf-21).
|
|
AU2019299439C1
(en)
|
2018-07-03 |
2025-06-26 |
Sotio Biotech, Inc. |
Chimeric receptors in combination with trans metabolism molecules enhancing glucose import and therapeutic uses thereof
|
|
WO2020014306A1
(en)
|
2018-07-10 |
2020-01-16 |
Immunogen, Inc. |
Met antibodies and immunoconjugates and uses thereof
|
|
FI3618928T3
(fi)
|
2018-07-13 |
2023-04-21 |
Alector Llc |
Anti-sortiliini-vasta-aineita ja menetelmiä niiden käyttämiseksi
|
|
MA53328A
(fr)
|
2018-07-27 |
2021-06-09 |
Alector Llc |
Anticorps anti-siglec-5 et leurs procédés d'utilisation
|
|
US20220193250A1
(en)
|
2018-08-02 |
2022-06-23 |
Dyne Therapeutics, Inc. |
Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
|
|
CA3108799A1
(en)
|
2018-08-09 |
2020-02-13 |
Bioverativ Therapeutics Inc. |
Nucleic acid molecules and uses thereof for non-viral gene therapy
|
|
PE20210343A1
(es)
|
2018-08-10 |
2021-02-23 |
Chugai Pharmaceutical Co Ltd |
Molecula de union al antigeno anti grupo de diferenciacion 137 (cd137) y su uso
|
|
MX2021001771A
(es)
|
2018-08-14 |
2021-07-16 |
Sotio Llc |
Polipéptidos del receptor de antígeno quimérico en combinación con moléculas del metabolismo trans que modulan el ciclo de krebs y usos terapéuticos de los mismos.
|
|
CA3108879A1
(en)
|
2018-08-21 |
2020-02-27 |
Albert Einstein College Of Medicine |
Monoclonal antibodies against human tim-3
|
|
TW202031273A
(zh)
|
2018-08-31 |
2020-09-01 |
美商艾歐凡斯生物治療公司 |
抗pd-1抗體難治療性之非小細胞肺癌(nsclc)病患的治療
|
|
SI3844189T1
(sl)
|
2018-08-31 |
2025-03-31 |
Regeneron Pharmaceuticals, Inc. |
Strategija odmerjanja, ki blaži sindrom sproščanja citokinov za bispecifična protitelesa CD3/CD20
|
|
BR112021003016A2
(pt)
|
2018-08-31 |
2021-05-18 |
Alector Llc |
anticorpos isolados, ácido nucleico isolado, vetor, célula hospedeira, métodos para produzir um anticorpo e para prevenir, reduzir o risco ou tratar uma doença e composição farmacêutica
|
|
WO2020051507A1
(en)
|
2018-09-06 |
2020-03-12 |
The Broad Institute, Inc. |
Nucleic acid assemblies for use in targeted delivery
|
|
CA3110530A1
(en)
|
2018-09-11 |
2020-03-19 |
Amgen Inc. |
Methods of modulating antibody-dependent cell-mediated cytotoxicity
|
|
US10899826B1
(en)
|
2018-09-13 |
2021-01-26 |
Teva Pharmaceuticals International Gmbh |
Pharmaceutical compositions for an anti-CGRP antagonist antibody
|
|
WO2020060781A1
(en)
|
2018-09-17 |
2020-03-26 |
Abcuro, Inc. |
Anti-klrg1 antibodies
|
|
WO2020065409A2
(en)
|
2018-09-28 |
2020-04-02 |
Lyvgen Biopharma Co., Ltd. |
Anti-cd40 binding molecules having engineered fc domains and therapeutic uses thereof
|
|
EP3827016B1
(en)
|
2018-10-15 |
2025-12-03 |
Elixiron Immunotherapeutics (Hong Kong) Limited |
Antibodies to granulocyte-macrophage colony stimulating factor and uses thereof
|
|
WO2020089437A1
(en)
|
2018-10-31 |
2020-05-07 |
Engmab Sàrl |
Combination therapy
|
|
TW202039831A
(zh)
|
2018-11-05 |
2020-11-01 |
美商艾歐凡斯生物治療公司 |
對抗pd-1抗體呈現難治性之非小細胞肺癌(nsclc)病患之治療
|
|
JP7682789B2
(ja)
|
2018-11-16 |
2025-05-26 |
アルバート アインシュタイン カレッジ オブ メディスン |
B7-H3のIgVドメインに対するモノクローナル抗体及びその使用
|
|
US20220106400A1
(en)
|
2018-11-28 |
2022-04-07 |
Bristol-Myers Squibb Company |
Antibodies comprising modified heavy constant regions
|
|
AU2019401647A1
(en)
|
2018-12-21 |
2021-07-08 |
Multitude Inc. |
Antibodies specific to MUC18
|
|
US11447551B2
(en)
|
2018-12-28 |
2022-09-20 |
Sparx Bioscience Limited |
Binding molecules specific for claudin 18.2, compositions and methods thereof, for the treatment of cancer and other diseases
|
|
AU2020204992A1
(en)
|
2019-01-04 |
2021-07-15 |
Resolve Therapeutics, Llc |
Treatment of sjogren's disease with nuclease fusion proteins
|
|
EP4434541A3
(en)
|
2019-01-23 |
2025-02-26 |
New York University |
Antibodies specific to delta 1 chain of t cell receptor
|
|
EP3914708A1
(en)
|
2019-01-24 |
2021-12-01 |
Massachusetts Institute Of Technology |
Nucleic acid nanostructure platform for antigen presentation and vaccine formulations formed therefrom
|
|
WO2020159836A1
(en)
|
2019-01-28 |
2020-08-06 |
Maple Biotech Llc |
Psmp antagonists for use in treatment of fibrotic disease of the lung, kidney or liver
|
|
JP2020117502A
(ja)
|
2019-01-28 |
2020-08-06 |
ファイザー・インク |
変形性関節症の徴候および症状を処置する方法
|
|
EP3927430A1
(en)
|
2019-02-18 |
2021-12-29 |
Pfizer Inc. |
Method of treatment of chronic low back pain
|
|
AU2020233284A1
(en)
|
2019-03-01 |
2021-09-16 |
Iovance Biotherapeutics, Inc. |
Expansion of tumor infiltrating lymphocytes from liquid tumors and therapeutic uses thereof
|
|
AU2020242042A1
(en)
|
2019-03-19 |
2021-09-16 |
Albert Einstein College Of Medicine |
Monoclonal antibodies for prevention and treatment of herpes simplex viral infections
|
|
JP7575401B2
(ja)
|
2019-04-03 |
2024-10-29 |
ジェンザイム・コーポレーション |
断片化が低減した抗アルファベータtcr結合ポリペプチド
|
|
US12496279B2
(en)
|
2019-04-11 |
2025-12-16 |
The Johns Hopkins University |
Nanoparticles for drug delivery to brain
|
|
GB2589049C
(en)
|
2019-04-11 |
2024-02-21 |
argenx BV |
Anti-IgE antibodies
|
|
WO2020214690A1
(en)
|
2019-04-15 |
2020-10-22 |
Qwixel Therapeutics |
Fusion protein composition(s) comprising targeted masked type i interferons (ifna and ifnb) and an antibody against tumor antigen, for use in the treatment of cancer
|
|
JP7501876B2
(ja)
|
2019-04-17 |
2024-06-18 |
国立大学法人広島大学 |
Il-6阻害剤及びccr2阻害剤を組み合わせて投与することを特徴とする泌尿器がんの治療剤
|
|
AU2020275348A1
(en)
|
2019-05-15 |
2021-12-09 |
Chugai Seiyaku Kabushiki Kaisha |
An antigen-binding molecule, a pharmaceutical composition, and a method
|
|
KR20220019018A
(ko)
|
2019-06-07 |
2022-02-15 |
아르제넥스 비브이비에이 |
피하 투여에 적합한 FcRn 억제제의 약학적 제형
|
|
BR112021025077A2
(pt)
|
2019-06-11 |
2022-05-03 |
Alector Llc |
Anticorpos anti-sortilina para uso em terapia
|
|
CN114174326A
(zh)
|
2019-06-18 |
2022-03-11 |
拜耳公司 |
长期稳定的肾上腺髓质素类似物及其用途
|
|
NZ783169A
(en)
|
2019-06-25 |
2024-12-20 |
Gilead Sciences Inc |
Flt3l-fc fusion proteins and methods of use
|
|
US11905532B2
(en)
|
2019-06-25 |
2024-02-20 |
Massachusetts Institute Of Technology |
Compositions and methods for molecular memory storage and retrieval
|
|
CR20220049A
(es)
|
2019-07-10 |
2022-03-02 |
Chugai Pharmaceutical Co Ltd |
Moléculas de unión a claudina-6 y usos de las mismas
|
|
AU2020321969A1
(en)
|
2019-07-31 |
2022-03-17 |
Alector Llc |
Anti-MS4A4A antibodies and methods of use thereof
|
|
DE102019121007A1
(de)
|
2019-08-02 |
2021-02-04 |
Immatics Biotechnologies Gmbh |
Antigenbindende Proteine, die spezifisch an MAGE-A binden
|
|
US20210032370A1
(en)
|
2019-08-02 |
2021-02-04 |
Immatics Biotechnologies Gmbh |
Recruiting agent further binding an mhc molecule
|
|
KR20220088428A
(ko)
|
2019-09-26 |
2022-06-27 |
주식회사 에스티큐브앤컴퍼니 |
글리코실화된 ctla-4에 대해 특이적인 항체 및 이의 사용 방법
|
|
JP7803014B2
(ja)
|
2019-09-30 |
2026-01-21 |
バイオベラティブ セラピューティクス インコーポレイテッド |
レンチウイルスベクター製剤
|
|
EP4017542A1
(en)
|
2019-10-04 |
2022-06-29 |
Tae Life Sciences |
Antibody compositions comprising fc mutations and site-specific conjugation properties
|
|
EP4041768A1
(en)
|
2019-10-09 |
2022-08-17 |
StCube & Co. |
Antibodies specific to glycosylated lag3 and methods of use thereof
|
|
CA3152623A1
(en)
|
2019-10-11 |
2021-04-15 |
Richard D. Cummings |
Anti-tn antibodies and uses thereof
|
|
WO2021086948A1
(en)
|
2019-10-28 |
2021-05-06 |
Georgia Tech Research Corporation |
Mrna-encoded antibodies for contraception
|
|
WO2021086953A1
(en)
|
2019-10-28 |
2021-05-06 |
Georgia Tech Research Corporation |
Compositions and methods for prophylaxis of hiv
|
|
CA3160574A1
(en)
*
|
2019-12-03 |
2021-06-10 |
Fubin LI |
Antibody fc region having enhanced binding affinty to fcyriib
|
|
JP2023505279A
(ja)
|
2019-12-05 |
2023-02-08 |
アレクトル エルエルシー |
抗trem2抗体の使用方法
|
|
CN115916817A
(zh)
|
2019-12-06 |
2023-04-04 |
朱诺治疗学股份有限公司 |
针对bcma靶向结合结构域的抗独特型抗体及相关组合物和方法
|
|
US12570749B2
(en)
|
2019-12-06 |
2026-03-10 |
Juno Therapeutics, Inc. |
Anti-idiotypic antibodies to GPRC5D-targeted binding domains and related compositions and methods
|
|
KR20220127243A
(ko)
|
2019-12-12 |
2022-09-19 |
알렉터 엘엘씨 |
항-cd33 항체의 사용 방법
|
|
BR112022011570A2
(pt)
|
2019-12-13 |
2022-12-13 |
Alector Llc |
Anticorpos anti-mertk e métodos de uso dos mesmos
|
|
BR112022009723A2
(pt)
|
2019-12-17 |
2022-08-09 |
Pfizer |
Anticorpos específicos para cd47, pd-l1, e usos dos mesmos
|
|
LT4087875T
(lt)
|
2020-01-08 |
2024-10-25 |
argenx BV |
Žmogaus neonatalinių fc receptorių (fcrn) antagonistai, skirti pūslinių ligų gydymui
|
|
US20230132241A1
(en)
|
2020-01-15 |
2023-04-27 |
Immatics Biotechnologies Gmbh |
Antigen binding proteins specifically binding prame
|
|
CN115362167A
(zh)
|
2020-02-06 |
2022-11-18 |
百时美施贵宝公司 |
Il-10及其用途
|
|
WO2021161197A1
(en)
|
2020-02-11 |
2021-08-19 |
Crispr Therapeutics Ag |
Anti-idiotype antibodies targeting anti-cd19 chimeric antigen receptor
|
|
CA3167851A1
(en)
|
2020-02-24 |
2021-09-02 |
Francesca CIGNARELLA |
Methods of use of anti-trem2 antibodies
|
|
CA3169521A1
(en)
|
2020-02-28 |
2021-09-02 |
Marie-Priscille Brun |
Modified binding polypeptides for optimized drug conjugation
|
|
EP4118105A2
(en)
|
2020-03-09 |
2023-01-18 |
Pfizer Inc. |
Cd80-fc fusion protein and uses thereof
|
|
WO2021194951A1
(en)
|
2020-03-23 |
2021-09-30 |
Centivax, Inc. |
Anti-sars-cov-2 antibodies derived from 2dd8
|
|
WO2021202590A1
(en)
|
2020-03-31 |
2021-10-07 |
Alector Llc |
Anti-mertk antibodies and methods of use thereof
|
|
IL296992A
(en)
|
2020-04-03 |
2022-12-01 |
Alector Llc |
Methods for using anti-trem2 antibodies
|
|
WO2021207348A1
(en)
|
2020-04-07 |
2021-10-14 |
Albert Einstein College Of Medicine |
Method of treating and preventing ocular disease with hsv-2 delta gd
|
|
WO2021224850A1
(en)
|
2020-05-06 |
2021-11-11 |
Crispr Therapeutics Ag |
Mask peptides and masked anti-ptk7 antibodies comprising such
|
|
WO2021231798A1
(en)
|
2020-05-13 |
2021-11-18 |
Disc Medicine, Inc. |
Anti-hemojuvelin (hjv) antibodies for treating myelofibrosis
|
|
WO2021231732A1
(en)
|
2020-05-15 |
2021-11-18 |
Bristol-Myers Squibb Company |
Antibodies to garp
|
|
GB2595299B
(en)
|
2020-05-21 |
2022-08-03 |
Mabsolve Ltd |
Modified immunoglobulin FC regions
|
|
EP4159236A4
(en)
|
2020-05-29 |
2024-08-21 |
Chugai Seiyaku Kabushiki Kaisha |
Antibody-containing formulation
|
|
US20210380707A1
(en)
|
2020-06-04 |
2021-12-09 |
Crispr Therapeutics Ag |
Anti-cd70 antibodies and uses thereof
|
|
JPWO2021251340A1
(no)
|
2020-06-08 |
2021-12-16 |
|
|
|
WO2021257512A1
(en)
|
2020-06-15 |
2021-12-23 |
Academia Sinica |
Humanized ace2-fc fusion protein for treatment and prevention of sars-cov-2 infection
|
|
IL299333A
(en)
|
2020-06-24 |
2023-02-01 |
Bioverativ Therapeutics Inc |
Methods for the purification of viral vectors
|
|
EP4171614A1
(en)
|
2020-06-29 |
2023-05-03 |
Resolve Therapeutics, LLC |
Treatment of sjogren's syndrome with nuclease fusion proteins
|
|
BR112023000650A2
(pt)
|
2020-07-14 |
2023-01-31 |
Pfizer |
Vírus vaccinia recombinante
|
|
CN116323668A
(zh)
|
2020-07-17 |
2023-06-23 |
辉瑞公司 |
治疗性抗体及其用途
|
|
AU2021312871A1
(en)
|
2020-07-21 |
2023-02-09 |
Allogene Therapeutics, Inc. |
Chimeric antigen receptors with enhanced signaling and activities and uses thereof
|
|
US11795238B2
(en)
|
2020-08-04 |
2023-10-24 |
Crispr Therapeutics Ag |
Anti-idiotype antibodies targeting anti-CD70 chimeric antigen receptor
|
|
KR20230095918A
(ko)
|
2020-08-05 |
2023-06-29 |
주노 쎄러퓨티크스 인코퍼레이티드 |
Ror1-표적 결합 도메인에 대한 항이디오타입 항체 및 관련 조성물 및 방법
|
|
WO2022043861A1
(en)
|
2020-08-25 |
2022-03-03 |
Crispr Therapeutics Ag |
Anti-idiotype antibodies targeting anti-bcma chimeric antigen receptor
|
|
IL300256A
(en)
|
2020-08-25 |
2023-03-01 |
Gilead Sciences Inc |
Multispecific Antigen Binding Molecules Targeting HIV and Methods of Use
|
|
WO2022076606A1
(en)
|
2020-10-06 |
2022-04-14 |
Iovance Biotherapeutics, Inc. |
Treatment of nsclc patients with tumor infiltrating lymphocyte therapies
|
|
US20230372397A1
(en)
|
2020-10-06 |
2023-11-23 |
Iovance Biotherapeutics, Inc. |
Treatment of nsclc patients with tumor infiltrating lymphocyte therapies
|
|
TWI815194B
(zh)
|
2020-10-22 |
2023-09-11 |
美商基利科學股份有限公司 |
介白素2-Fc融合蛋白及使用方法
|
|
JP2023554589A
(ja)
|
2020-11-27 |
2023-12-28 |
ジェネラル ナノセラピューティクス エルエルシー |
免疫媒介性疾患の治療のための方法及び組成物
|
|
US20240101681A1
(en)
|
2020-12-02 |
2024-03-28 |
Alector Llc |
Methods of use of anti-sortilin antibodies
|
|
JP2024501452A
(ja)
|
2020-12-11 |
2024-01-12 |
アイオバンス バイオセラピューティクス,インコーポレイテッド |
Braf阻害剤及び/またはmek阻害剤と併用した腫瘍浸潤リンパ球治療によるがん患者の治療
|
|
CA3202483A1
(en)
|
2020-12-17 |
2022-06-23 |
Maria Fardis |
Treatment with tumor infiltrating lymphocyte therapies in combination with ctla-4 and pd-1 inhibitors
|
|
CA3202473A1
(en)
|
2020-12-17 |
2022-06-23 |
Friedrich Graf Finckenstein |
Treatment of cancers with tumor infiltrating lymphocytes
|
|
WO2022127793A1
(zh)
|
2020-12-18 |
2022-06-23 |
珠海泰诺麦博生物技术有限公司 |
呼吸道合胞病毒特异性结合分子
|
|
CA3203382A1
(en)
|
2020-12-31 |
2022-07-07 |
Adrian Emanual Wells |
Devices and processes for automated production of tumor infiltrating lymphocytes
|
|
WO2022165260A1
(en)
|
2021-01-29 |
2022-08-04 |
Iovance Biotherapeutics, Inc. |
Methods of making modified tumor infiltrating lymphocytes and their use in adoptive cell therapy
|
|
EP4301362A1
(en)
|
2021-03-02 |
2024-01-10 |
CGRP Diagnostics GmbH |
Treatment and/or reduction of occurrence of migraine
|
|
TW202300014A
(zh)
|
2021-03-05 |
2023-01-01 |
美商艾歐凡斯生物治療公司 |
腫瘤儲存及細胞培養組成物
|
|
JP2024512002A
(ja)
|
2021-03-18 |
2024-03-18 |
アレクトル エルエルシー |
抗tmem106b抗体、及び、その使用方法
|
|
US20240191191A1
(en)
|
2021-03-19 |
2024-06-13 |
Iovance Biotherapeutics, Inc. |
Methods for infiltrating lymphocyte (til) expansion related to cd39/cd69 selection and gene knockout in tils
|
|
WO2022195504A1
(en)
|
2021-03-19 |
2022-09-22 |
Pfizer Inc. |
Method of treating osteoarthritis pain with an anti ngf antibody
|
|
JP2024511420A
(ja)
|
2021-03-22 |
2024-03-13 |
ジュノー セラピューティクス インコーポレイテッド |
ウイルスベクター粒子の効力を評価する方法
|
|
EP4314814A1
(en)
|
2021-03-22 |
2024-02-07 |
Juno Therapeutics, Inc. |
Methods of determining potency of a therapeutic cell composition
|
|
WO2022204274A1
(en)
|
2021-03-23 |
2022-09-29 |
Alector Llc |
Anti-tmem106b antibodies for treating and preventing coronavirus infections
|
|
WO2022204155A1
(en)
|
2021-03-23 |
2022-09-29 |
Iovance Biotherapeutics, Inc. |
Cish gene editing of tumor infiltrating lymphocytes and uses of same in immunotherapy
|
|
WO2022204564A2
(en)
|
2021-03-25 |
2022-09-29 |
Iovance Biotherapeutics, Inc. |
Methods and compositions for t-cell coculture potency assays and use with cell therapy products
|
|
TW202308669A
(zh)
|
2021-04-19 |
2023-03-01 |
美商艾歐凡斯生物治療公司 |
嵌合共刺激性受體、趨化激素受體及彼等於細胞免疫治療之用途
|
|
BR112023022765A2
(pt)
|
2021-05-05 |
2024-01-02 |
Immatics Biotechnologies Gmbh |
Proteínas de ligação ao antígeno que ligam especificamente o prame
|
|
JP2024519029A
(ja)
|
2021-05-17 |
2024-05-08 |
アイオバンス バイオセラピューティクス,インコーポレイテッド |
Pd-1遺伝子編集された腫瘍浸潤リンパ球及び免疫療法におけるその使用
|
|
WO2022245671A1
(en)
|
2021-05-18 |
2022-11-24 |
Gilead Sciences, Inc. |
Methods of using flt3l-fc fusion proteins
|
|
JP2022184105A
(ja)
|
2021-05-31 |
2022-12-13 |
ワイズ・エー・シー株式会社 |
抗cd26抗体と免疫チェックポイント阻害剤との併用療法
|
|
CN117642426A
(zh)
|
2021-06-16 |
2024-03-01 |
艾莱克特有限责任公司 |
双特异性抗MerTK和抗PDL1抗体及其使用方法
|
|
WO2022265912A1
(en)
|
2021-06-16 |
2022-12-22 |
Gundersen Lutheran Medical Foundation, Inc. |
Antibodies targeting an amphiregulin-derived cell surface neo-epitope
|
|
JP2024527493A
(ja)
|
2021-06-16 |
2024-07-25 |
アレクトル エルエルシー |
一価の抗MerTK抗体及びその使用方法
|
|
KR20240021943A
(ko)
|
2021-06-18 |
2024-02-19 |
남미 테라퓨틱스, 인크. |
암의 치료에 사용하기 위한 마스킹된 유형 I 인터페론 (IFNα 및 IFNβ)을 포함하는 융합 단백질 조성물(들) 및 그의 방법
|
|
WO2023281485A1
(en)
|
2021-07-09 |
2023-01-12 |
Bright Peak Therapeutics Ag |
Modified il-2 polypeptides for treatment of inflammatory and autoimmune diseases
|
|
KR20240041378A
(ko)
|
2021-07-09 |
2024-03-29 |
브라이트 피크 테라퓨틱스 아게 |
체크포인트 억제제와 il-2의 접합체 및 이의 용도
|
|
WO2023281482A1
(en)
|
2021-07-09 |
2023-01-12 |
Bright Peak Therapeutics Ag |
Cd20-targeted il-2 and its uses
|
|
US20230201364A1
(en)
|
2021-07-09 |
2023-06-29 |
Bright Peak Therapeutics Ag |
Antibody conjugates and manufacture thereof
|
|
EP4366781A1
(en)
|
2021-07-09 |
2024-05-15 |
Bright Peak Therapeutics AG |
Checkpoint inhibitors conjugated to il-2, and uses thereof
|
|
JP2024526898A
(ja)
|
2021-07-22 |
2024-07-19 |
アイオバンス バイオセラピューティクス,インコーポレイテッド |
固形腫瘍断片の凍結保存のための方法
|
|
WO2023007374A1
(en)
|
2021-07-27 |
2023-02-02 |
Pfizer Inc. |
Method of treatment of cancer pain with tanezumab
|
|
JP2024527977A
(ja)
|
2021-07-27 |
2024-07-26 |
ノヴァブ, インコーポレイテッド |
免疫エフェクター機能を有する操作されたvlrb抗体
|
|
JP2024527961A
(ja)
|
2021-07-28 |
2024-07-26 |
アイオバンス バイオセラピューティクス,インコーポレイテッド |
Kras阻害剤と併用した腫瘍浸潤リンパ球療法によるがん患者の治療
|
|
US20250109188A1
(en)
|
2021-08-24 |
2025-04-03 |
Cgrp Diagnostics Gmbh |
Preventative treatment of migraine
|
|
IL311333A
(en)
|
2021-09-09 |
2024-05-01 |
Iovance Biotherapeutics Inc |
Processes for generating til products using pd-1 talen knockdown
|
|
EP4404969A1
(en)
|
2021-09-24 |
2024-07-31 |
Iovance Biotherapeutics, Inc. |
Expansion processes and agents for tumor infiltrating lymphocytes
|
|
AU2022349103A1
(en)
|
2021-09-27 |
2024-03-28 |
Sotio Biotech Inc. |
Chimeric receptor polypeptides in combination with trans metabolism molecules that re-direct glucose metabolites out of the glycolysis pathway and therapeutic uses thereof
|
|
US20230190807A1
(en)
|
2021-10-06 |
2023-06-22 |
Immatics Biotechnologies Gmbh |
Tcr compounds, compositions, and methods of treating
|
|
EP4419558A1
(en)
|
2021-10-19 |
2024-08-28 |
Alector LLC |
Anti-cd300lb antibodies and methods of use thereof
|
|
US20230187042A1
(en)
|
2021-10-27 |
2023-06-15 |
Iovance Biotherapeutics, Inc. |
Systems and methods for coordinating manufacturing of cells for patient-specific immunotherapy
|
|
JP2024541058A
(ja)
|
2021-11-03 |
2024-11-06 |
ハンジョウ ディーエーシー バイオテック シーオー.,エルティディ. |
抗体の特異的共役
|
|
WO2023081898A1
(en)
|
2021-11-08 |
2023-05-11 |
Alector Llc |
Soluble cd33 as a biomarker for anti-cd33 efficacy
|
|
WO2023081925A1
(en)
|
2021-11-08 |
2023-05-11 |
Immatics Biotechnologies Gmbh |
Adoptive cell therapy combination treatment and compositions thereof
|
|
AU2022388729A1
(en)
|
2021-11-10 |
2024-05-16 |
Iovance Biotherapeutics, Inc. |
Methods of expansion treatment utilizing cd8 tumor infiltrating lymphocytes
|
|
EP4433160A1
(en)
|
2021-11-17 |
2024-09-25 |
Disc Medicine, Inc. |
Methods for treating anemia of kidney disease
|
|
JP2024540484A
(ja)
|
2021-11-17 |
2024-10-31 |
アルトゥルバイオ, インコーポレイテッド |
抗psgl-1抗体をjak阻害剤と組み合わせて使用してt細胞媒介性炎症性疾患またはがんを治療する方法
|
|
WO2023100153A1
(en)
|
2021-12-03 |
2023-06-08 |
Crispr Therapeutics Ag |
Use of anti-cd70 antibodies for identifying subjects susceptible for treatment with nk cell-based anti-cd70 therapy
|
|
CA3236108A1
(en)
|
2022-01-18 |
2023-07-27 |
Paul Sebastian VAN DER WONING |
Galectin-10 antibodies
|
|
EP4469066A1
(en)
|
2022-01-28 |
2024-12-04 |
Iovance Biotherapeutics, Inc. |
Tumor infiltrating lymphocytes engineered to express payloads
|
|
CA3243281A1
(en)
|
2022-01-28 |
2023-08-03 |
Georgiamune Inc. |
ANTIBODIES DIRECTED AGAINST PROGRAMMED CELL DEATH PROTEIN 1 PD-1 AGONISTS
|
|
CA3243419A1
(en)
|
2022-01-28 |
2023-08-03 |
Iovance Biotherapeutics, Inc. |
CYTOKINE-ASSOCIATED TUMOR-INFILTRATING LYMPHOCYTE COMPOSITIONS AND PROCESSES
|
|
WO2023158514A1
(en)
|
2022-02-18 |
2023-08-24 |
Massachusetts Institute Of Technology |
Cancer treatment by combined inhibition of polo-like kinase and microtubule polymerization
|
|
JP2025508823A
(ja)
|
2022-02-23 |
2025-04-10 |
ブライト ピーク セラピューティクス エージー |
免疫抗原特異的il-18免疫サイトカイン及びその使用
|
|
WO2023164516A1
(en)
|
2022-02-23 |
2023-08-31 |
Alector Llc |
Methods of use of anti-trem2 antibodies
|
|
AU2023228391A1
(en)
|
2022-03-03 |
2024-09-19 |
Pfizer Inc. |
Multispecific antibodies binding to il-4, il-13 and/or tslp and uses thereof
|
|
WO2023192872A1
(en)
|
2022-03-28 |
2023-10-05 |
Massachusetts Institute Of Technology |
Rna scaffolded wireframe origami and methods thereof
|
|
JP2025512313A
(ja)
|
2022-04-06 |
2025-04-17 |
アイオバンス バイオセラピューティクス,インコーポレイテッド |
腫瘍浸潤リンパ球療法によるnsclc患者の治療
|
|
PE20251170A1
(es)
|
2022-04-06 |
2025-04-23 |
Mirobio Ltd |
Anticuerpos cd200r disenados por ingenieria y usos de estos
|
|
WO2023201369A1
(en)
|
2022-04-15 |
2023-10-19 |
Iovance Biotherapeutics, Inc. |
Til expansion processes using specific cytokine combinations and/or akti treatment
|
|
US20250281537A1
(en)
|
2022-05-10 |
2025-09-11 |
Iovance Biotherapeutics, Inc. |
Treatment of cancer patients with tumor infiltrating lymphocyte therapies in combination with an il-15r agonist
|
|
US20240059799A1
(en)
|
2022-05-11 |
2024-02-22 |
Pfizer Inc. |
Anti-tl1a antibodies and methods of use thereof
|
|
WO2023218320A1
(en)
|
2022-05-11 |
2023-11-16 |
Pfizer Inc. |
Anti-lymphotoxin beta receptor antibodies and methods of use thereof
|
|
KR20250017237A
(ko)
|
2022-05-26 |
2025-02-04 |
화이자 인코포레이티드 |
항-tnfr2 항체 및 그의 사용 방법
|
|
TW202405002A
(zh)
|
2022-05-31 |
2024-02-01 |
美商輝瑞大藥廠 |
抗-bmp9抗體及其使用方法
|
|
KR20250035053A
(ko)
|
2022-06-07 |
2025-03-11 |
리제너론 파아마슈티컬스, 인크. |
T 세포 활성을 조절하기 위한 다중특이적 분자 및 이의 용도
|
|
WO2023240124A1
(en)
|
2022-06-07 |
2023-12-14 |
Regeneron Pharmaceuticals, Inc. |
Pseudotyped viral particles for targeting tcr-expressing cells
|
|
AU2023291786A1
(en)
|
2022-06-15 |
2024-12-12 |
argenx BV |
Ph-dependent hsa-binding molecules and methods of use
|
|
KR20250010064A
(ko)
|
2022-06-17 |
2025-01-20 |
화이자 인코포레이티드 |
Il-12 변이체, 항-pd1 항체, 융합 단백질, 및 그의 용도
|
|
WO2024011114A1
(en)
|
2022-07-06 |
2024-01-11 |
Iovance Biotherapeutics, Inc. |
Devices and processes for automated production of tumor infiltrating lymphocytes
|
|
WO2024026447A1
(en)
|
2022-07-29 |
2024-02-01 |
Alector Llc |
Anti-gpnmb antibodies and methods of use thereof
|
|
US20260021181A1
(en)
|
2022-08-01 |
2026-01-22 |
Iovance Biotherapeutics, Inc. |
Chimeric costimulatory receptors, chemokine receptors, and the use of same in cellular immunotherapies
|
|
EP4565611A1
(en)
|
2022-08-03 |
2025-06-11 |
Pfizer Inc. |
Anti- il27r antibodies and methods of use thereof
|
|
US20260071003A1
(en)
|
2022-09-01 |
2026-03-12 |
University Of Georgia Research Foundation, Inc. |
Compositions and methods for directing apolipoprotein l1 to induce mammalian cell death
|
|
WO2024064752A2
(en)
|
2022-09-20 |
2024-03-28 |
Yale University |
Compositions of wet adhesives derived from vibrio cholerae biofilm adhesins and methods thereof
|
|
KR20250060305A
(ko)
|
2022-09-21 |
2025-05-07 |
사노피 바이오테크놀로지 |
인간화 항-il-1r3 항체 및 사용 방법
|
|
KR20250090287A
(ko)
|
2022-10-19 |
2025-06-19 |
멀티튜드 테라퓨틱스 인코퍼레이티드 |
항체, 항체-약물 접합체, 이의 제조 및 용도
|
|
WO2024086796A1
(en)
|
2022-10-20 |
2024-04-25 |
Alector Llc |
Anti-ms4a4a antibodies with amyloid-beta therapies
|
|
AU2023369561A1
(en)
|
2022-10-25 |
2025-06-12 |
Ablynx N.V. |
Glycoengineered fc variant polypeptides with enhanced effector function
|
|
WO2024098024A1
(en)
|
2022-11-04 |
2024-05-10 |
Iovance Biotherapeutics, Inc. |
Expansion of tumor infiltrating lymphocytes from liquid tumors and therapeutic uses thereof
|
|
JP2025537155A
(ja)
|
2022-11-04 |
2025-11-14 |
アイオバンス バイオセラピューティクス,インコーポレイテッド |
Cd39/cd103選択に関連した腫瘍浸潤リンパ球(til)拡張のための方法
|
|
WO2024112571A2
(en)
|
2022-11-21 |
2024-05-30 |
Iovance Biotherapeutics, Inc. |
Two-dimensional processes for the expansion of tumor infiltrating lymphocytes and therapies therefrom
|
|
WO2024112711A2
(en)
|
2022-11-21 |
2024-05-30 |
Iovance Biotherapeutics, Inc. |
Methods for assessing proliferation potency of gene-edited t cells
|
|
JP2026503002A
(ja)
|
2023-01-06 |
2026-01-27 |
アレクトル エルエルシー |
抗il18結合タンパク質抗体及びその使用方法
|
|
US20240417436A1
(en)
|
2023-01-11 |
2024-12-19 |
Bright Peak Therapeutics Ag |
Conditionally activated immunocytokines and methods of use
|
|
WO2024150158A1
(en)
|
2023-01-11 |
2024-07-18 |
Bright Peak Therapeutics Ag |
Il-7 polypeptides, immunocytokines comprising same, and uses thereof
|
|
WO2024151885A1
(en)
|
2023-01-13 |
2024-07-18 |
Iovance Biotherapeutics, Inc. |
Use of til as maintenance therapy for nsclc patients who achieved pr/cr after prior therapy
|
|
EP4662230A1
(en)
|
2023-02-08 |
2025-12-17 |
ImmunOs Therapeutics AG |
Fusion proteins of ss2 microglobulin, hla heavy chain polypeptides, and inhibitor of cd47-sirpa
|
|
EP4673469A1
(en)
|
2023-03-02 |
2026-01-07 |
Alloy Therapeutics, Inc. |
Anti-cd22 antibodies and uses thereof
|
|
AU2024233763A1
(en)
|
2023-03-03 |
2025-10-16 |
Celldex Therapeutics, Inc. |
Anti-stem cell factor (scf) and anti-thymic stromal lymphopoietin (tslp) antibodies and bispecific constructs
|
|
US12421288B2
(en)
|
2023-03-16 |
2025-09-23 |
A-Alpha Bio |
Interferon alpha-2 variants
|
|
CN121311765A
(zh)
|
2023-04-18 |
2026-01-09 |
朱诺治疗学股份有限公司 |
评估治疗性细胞组合物的效力的细胞毒性测定
|
|
WO2024218650A1
(en)
|
2023-04-19 |
2024-10-24 |
Pfizer Inc. |
Lilrb1 and lilrb2 antibodies and methods of use thereof
|
|
WO2024226829A2
(en)
|
2023-04-26 |
2024-10-31 |
Yale University |
Enpp3-binding molecules, compositions formed therefrom, and methods of use thereof for the treatment of cancer
|
|
CN116769014A
(zh)
*
|
2023-06-07 |
2023-09-19 |
河南省农业科学院动物免疫学重点实验室 |
一种牛IgG Fc受体boFcγRI的线性配体结合表位
|
|
KR20260026054A
(ko)
|
2023-06-13 |
2026-02-25 |
애드센트릭스 테라퓨틱스 잉크. |
넥틴-4 단백질에 결합하는 항체 및 항체 약물 접합체 (adc)와 관련된 방법 및 조성물
|
|
WO2025015318A2
(en)
|
2023-07-13 |
2025-01-16 |
Iovance Biotherapeutics, Inc. |
Cytokine encoding lentiviral vectors and uses thereof for making tumor infiltrating lymphocytes
|
|
WO2025019790A1
(en)
|
2023-07-19 |
2025-01-23 |
Iovance Biotherapeutics, Inc. |
Treatment of cancer patients with tumor infiltrating lymphocyte therapies in combination with trop-2 targeting adc
|
|
WO2025022280A1
(en)
|
2023-07-21 |
2025-01-30 |
Astrazeneca Ab |
Treatment of neurodegenerative diseases
|
|
TW202506719A
(zh)
|
2023-07-27 |
2025-02-16 |
德商艾瑪提克生物技術有限公司 |
針對mageb2之抗原結合蛋白
|
|
US12281147B2
(en)
|
2023-08-14 |
2025-04-22 |
A-Alpha Bio, Inc. |
Interleukin 21 variants
|
|
WO2025041077A1
(en)
|
2023-08-23 |
2025-02-27 |
Sanofi |
Ctla-4-based lysosomal degraders and uses thereof
|
|
WO2025041101A1
(en)
|
2023-08-23 |
2025-02-27 |
Bright Peak Therapeutics Ag |
Activatable il-18 immunocytokines and uses thereof
|
|
US20250188166A1
(en)
|
2023-08-23 |
2025-06-12 |
Bright Peak Therapeutics Ag |
Il-18 polypeptides fused to immune cell antigen specific binding polypeptides and uses thereof
|
|
US20250186597A1
(en)
|
2023-08-23 |
2025-06-12 |
Bright Peak Therapeutics Ag |
Targeted immune activation with il-18 immunocytokines
|
|
US20250109187A1
(en)
|
2023-09-28 |
2025-04-03 |
Novavax, Inc. |
ANTI-SARS-CoV-2 SPIKE (S) ANTIBODIES AND THEIR USE IN TREATING COVID-19
|
|
TW202519543A
(zh)
|
2023-09-29 |
2025-05-16 |
美商崔克斯生物公司 |
TNF-α變體融合分子
|
|
WO2025076081A1
(en)
|
2023-10-03 |
2025-04-10 |
Absci Corporation |
Tl1a associated antibody compositions and methods of use
|
|
WO2025096560A1
(en)
|
2023-10-30 |
2025-05-08 |
Allogene Therapeutics, Inc. |
Engineered cells
|
|
WO2025101484A1
(en)
|
2023-11-06 |
2025-05-15 |
Iovance Biotherapeutics, Inc. |
Treatment of endometrial cancers with tumor infiltrating lymphocyte therapies
|
|
TW202535956A
(zh)
|
2023-11-10 |
2025-09-16 |
美商輝瑞大藥廠 |
抗MIGIS-α抗體及其使用方法
|
|
WO2025104668A1
(en)
|
2023-11-17 |
2025-05-22 |
Pfizer Inc. |
Anti-gastric inhibitory polypeptide receptor (gipr) antibodies and antibody conjugates for the treatment of metabolic disorders
|
|
WO2025122885A1
(en)
|
2023-12-08 |
2025-06-12 |
Absci Corporation |
Anti-her2 associated antibody compositions designed by artificial intelligence and methods of use
|
|
GB202319605D0
(en)
|
2023-12-20 |
2024-01-31 |
argenx BV |
Monovalent binding molecules and methods of use
|
|
WO2025133694A1
(en)
|
2023-12-20 |
2025-06-26 |
argenx BV |
Fcrn/hsa-binding molecules and methods of use
|
|
WO2025147696A1
(en)
|
2024-01-05 |
2025-07-10 |
Resolve Therapeutics, Llc |
Treatment of symptoms associated with sars-cov viral infection or a prior sars-cov viral infection with nuclease agents
|
|
US12527877B2
(en)
|
2024-01-24 |
2026-01-20 |
Arrowhead Pharmaceuticals, Inc. |
Anti-transferrin receptor antibodies, conjugates thereof, and uses thereof
|
|
WO2025171182A1
(en)
|
2024-02-08 |
2025-08-14 |
Iovance Biotherapeutics, Inc. |
Treatment of cancer patients with tumor infiltrating lymphocyte therapies in combination with cancer vaccine
|
|
WO2025233432A1
(en)
|
2024-05-07 |
2025-11-13 |
Immatics Biotechnologies Gmbh |
Use and dosage of an antigen-binding protein comprising a tcr specific for an hla-a*02 restricted peptide
|
|
WO2025233431A1
(en)
|
2024-05-07 |
2025-11-13 |
Immatics Biotechnologies Gmbh |
Heteromeric proteins comprising three heteromerization improving substitution, production, combinations and applications thereof
|
|
WO2025245176A1
(en)
|
2024-05-22 |
2025-11-27 |
Bristol-Myers Squibb Company |
Multispecific antibody constructs
|
|
WO2025257715A1
(en)
|
2024-06-12 |
2025-12-18 |
Seagen Inc. |
Anti-ceacam5 antibodies, antibody-drug conjugates and methods of uses thereof
|
|
WO2025264533A1
(en)
|
2024-06-17 |
2025-12-26 |
Adcentrx Therapeutics Inc. |
Methods and compositions related to antibody drug conjugates (adcs) that bind steap-1 proteins
|
|
WO2026006492A2
(en)
|
2024-06-25 |
2026-01-02 |
Ypsilon Therapeutics, Inc. |
Anti-prame/hla-a2 antibodies and uses thereof
|
|
WO2026006494A1
(en)
|
2024-06-25 |
2026-01-02 |
Alloy Therapeutics, Inc. |
Anti-cd3 antibodies and uses thereof
|
|
WO2026006495A1
(en)
|
2024-06-25 |
2026-01-02 |
Alloy Therapeutics, Inc. |
Anti-wt1/hla-a2 antibody and uses thereof
|
|
WO2026006784A1
(en)
|
2024-06-28 |
2026-01-02 |
Iovance Biotherapeutics, Inc. |
Methods of making tumor reactive peripheral blood lymphocytes (trpbl)
|
|
WO2026025031A1
(en)
|
2024-07-26 |
2026-01-29 |
Modernatx, Inc. |
Mrna encoding mageb2 tcer molecule
|
|
WO2026035866A1
(en)
|
2024-08-07 |
2026-02-12 |
Iovance Biotherapeutics, Inc. |
Treatment of cancer patients with tumor infiltrating lymphocyte therapies in combination with a lag-3 inhibitor and a pd-1 inhibitor
|