NO20091562L - 2-aryl-6-fenylimidazol{1,2-alpha}pyridin derivater, femstilling derav samt terapeutisk anvendelse derav - Google Patents

2-aryl-6-fenylimidazol{1,2-alpha}pyridin derivater, femstilling derav samt terapeutisk anvendelse derav

Info

Publication number
NO20091562L
NO20091562L NO20091562A NO20091562A NO20091562L NO 20091562 L NO20091562 L NO 20091562L NO 20091562 A NO20091562 A NO 20091562A NO 20091562 A NO20091562 A NO 20091562A NO 20091562 L NO20091562 L NO 20091562L
Authority
NO
Norway
Prior art keywords
optionally substituted
aryl
cycloalkyl
phenylimidazole
alpha
Prior art date
Application number
NO20091562A
Other languages
English (en)
Norwegian (no)
Inventor
Antonio Garcia Almario
Patrick A C Lardenois
Anne Olivier
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of NO20091562L publication Critical patent/NO20091562L/no

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Addiction (AREA)
  • Psychology (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO20091562A 2006-09-22 2009-04-20 2-aryl-6-fenylimidazol{1,2-alpha}pyridin derivater, femstilling derav samt terapeutisk anvendelse derav NO20091562L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0608350A FR2906250B1 (fr) 2006-09-22 2006-09-22 Derives de 2-aryl-6phenyl-imidazo(1,2-a) pyridines, leur preparation et leur application en therapeutique
PCT/FR2007/001517 WO2008034974A1 (fr) 2006-09-22 2007-09-19 DERIVES DE 2-ARYL-6-PHENYL-IMIDAZO[1,2-α]PYRIDINES, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE

Publications (1)

Publication Number Publication Date
NO20091562L true NO20091562L (no) 2009-04-20

Family

ID=37841968

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20091562A NO20091562L (no) 2006-09-22 2009-04-20 2-aryl-6-fenylimidazol{1,2-alpha}pyridin derivater, femstilling derav samt terapeutisk anvendelse derav

Country Status (43)

Country Link
US (1) US7915284B2 (sr)
EP (1) EP2069342B1 (sr)
JP (1) JP5336378B2 (sr)
KR (1) KR101470039B1 (sr)
CN (1) CN101516881B (sr)
AR (1) AR062897A1 (sr)
AT (1) ATE467633T1 (sr)
AU (1) AU2007298856B2 (sr)
BR (1) BRPI0718517A2 (sr)
CA (1) CA2662848C (sr)
CL (1) CL2007002733A1 (sr)
CO (1) CO6160308A2 (sr)
CR (1) CR10643A (sr)
CY (1) CY1110232T1 (sr)
DE (1) DE602007006525D1 (sr)
DK (1) DK2069342T3 (sr)
EA (1) EA017442B1 (sr)
ES (1) ES2345016T3 (sr)
FR (1) FR2906250B1 (sr)
GT (1) GT200900049A (sr)
HN (1) HN2009000502A (sr)
HR (1) HRP20100408T1 (sr)
IL (1) IL197352A (sr)
JO (1) JO2643B1 (sr)
MA (1) MA30792B1 (sr)
ME (1) ME00615B (sr)
MX (1) MX2009002802A (sr)
MY (1) MY145603A (sr)
NI (1) NI200900037A (sr)
NO (1) NO20091562L (sr)
NZ (1) NZ575337A (sr)
PE (1) PE20080671A1 (sr)
PL (1) PL2069342T3 (sr)
PT (1) PT2069342E (sr)
RS (1) RS51412B (sr)
SI (1) SI2069342T1 (sr)
SV (1) SV2009003193A (sr)
TN (1) TN2009000081A1 (sr)
TW (1) TWI381837B (sr)
UA (1) UA95976C2 (sr)
UY (1) UY30603A1 (sr)
WO (1) WO2008034974A1 (sr)
ZA (1) ZA200901551B (sr)

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FR2928924B1 (fr) 2008-03-21 2010-04-23 Sanofi Aventis Derives polysubstitues de 6-heteroaryle-imidazo°1,2-a! pyridines, leur preparation et leur application en therapeutique
FR2928922B1 (fr) * 2008-03-21 2010-04-23 Sanofi Aventis Derives de 2-aryl-6-phenyl-imidazo°1,2-a!pyridines polysubstitues, leur preparation et leur application en therapeutique
FR2928921B1 (fr) * 2008-03-21 2010-04-23 Sanofi Aventis Derives polysubstitues de 2-aryl-6-phenyl-imidazo°1,2-a!pyridines, leur preparation et leur application en therapeutique
FR2928923B1 (fr) * 2008-03-21 2010-04-23 Sanofi Aventis Derives polysubstitues de 2-heteroaryl-6-phenyl-imidazo °1,2-a!pyridines, leur preparation et leur application en therapeutiques
FR2933609B1 (fr) * 2008-07-10 2010-08-27 Fournier Lab Sa Utilisation de derives d'indole comme activateurs de nurr-1, pour le traitement de la maladie de parkinson.
FR2950344B1 (fr) * 2009-09-18 2011-11-25 Sanofi Aventis Derives de 5-phenyl-pyrazolopyridine, leur preparation et leur aplication en therapeutique.
FR2950345B1 (fr) * 2009-09-18 2011-09-23 Sanofi Aventis Derives acetyleniques de 5-phenyl-pyrazolopyridine, leur preparation et leur application en therapeutique
FR2953520B1 (fr) * 2009-12-04 2011-11-25 Sanofi Aventis Derives de diphenyl-pyrazolopyridines, leur preparation et leur application en therapeutique
RU2644949C2 (ru) * 2012-11-29 2018-02-15 Ф. Хоффманн-Ля Рош Аг Производные имидазопиридина, стимулирующие нейрогенез
TWI644899B (zh) 2013-02-04 2018-12-21 健生藥品公司 Flap調節劑
US9079866B2 (en) 2013-02-04 2015-07-14 Janssen Pharmaceutica Nv Flap modulators
CN105745208A (zh) * 2013-08-02 2016-07-06 韩国巴斯德研究所 一种抗感染化合物
CN107531693B (zh) 2015-04-10 2021-07-06 百济神州有限公司 作为吲哚胺、色氨酸二加氧酶抑制剂的5或8-取代的咪唑并[1,5-a]吡啶
US20170107216A1 (en) 2015-10-19 2017-04-20 Incyte Corporation Heterocyclic compounds as immunomodulators
AU2016358100B2 (en) 2015-11-19 2021-05-27 Incyte Corporation Heterocyclic compounds as immunomodulators
TW201726623A (zh) 2015-12-17 2017-08-01 英塞特公司 作為免疫調節劑之雜環化合物
TWI850624B (zh) 2015-12-22 2024-08-01 美商英塞特公司 作為免疫調節劑之雜環化合物
TW201808950A (zh) 2016-05-06 2018-03-16 英塞特公司 作為免疫調節劑之雜環化合物
US20170342060A1 (en) 2016-05-26 2017-11-30 Incyte Corporation Heterocyclic compounds as immunomodulators
DK3472167T3 (da) 2016-06-20 2022-09-05 Incyte Corp Heterocykliske forbindelser som immunomodulatorer
EP3484866B1 (en) 2016-07-14 2022-09-07 Incyte Corporation Heterocyclic compounds as immunomodulators
EP3504198B1 (en) 2016-08-29 2023-01-25 Incyte Corporation Heterocyclic compounds as immunomodulators
US10882856B2 (en) 2016-09-24 2021-01-05 Beigene, Ltd. 5 or 8-substituted imidazo [1,5-a] pyridines as selective inhibitors of indoleamine and/or tryptophane 2,3-dioxygenases
IL295660A (en) 2016-12-22 2022-10-01 Incyte Corp Benzooxazole derivatives as immunomodulators
ES2929193T3 (es) 2016-12-22 2022-11-25 Incyte Corp Derivados de tetrahidro imidazo[4,5-c]piridina como inductores de la internalización de PD-L1
EP3558963B1 (en) 2016-12-22 2022-03-23 Incyte Corporation Bicyclic heteroaromatic compounds as immunomodulators
ES2874756T3 (es) 2016-12-22 2021-11-05 Incyte Corp Derivados de triazolo[1,5-A]piridina como inmunomoduladores
EP3558973B1 (en) 2016-12-22 2021-09-15 Incyte Corporation Pyridine derivatives as immunomodulators
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RS64055B1 (sr) 2018-03-30 2023-04-28 Incyte Corp Heterociklična jedinjenja kao imunomodulatori
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JP7665593B2 (ja) 2019-08-09 2025-04-21 インサイト・コーポレイション Pd-1/pd-l1阻害剤の塩
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Also Published As

Publication number Publication date
CN101516881A (zh) 2009-08-26
JP2010504309A (ja) 2010-02-12
EA200970311A1 (ru) 2009-08-28
ATE467633T1 (de) 2010-05-15
KR101470039B1 (ko) 2014-12-05
DE602007006525D1 (de) 2010-06-24
HN2009000502A (es) 2011-07-11
CA2662848C (fr) 2014-12-23
HK1135388A1 (en) 2010-06-04
CR10643A (es) 2009-04-29
NZ575337A (en) 2011-12-22
AU2007298856B2 (en) 2012-08-09
IL197352A (en) 2014-11-30
HRP20100408T1 (hr) 2010-09-30
ZA200901551B (en) 2010-06-30
UY30603A1 (es) 2008-05-02
TWI381837B (zh) 2013-01-11
CL2007002733A1 (es) 2008-04-11
AU2007298856A1 (en) 2008-03-27
DK2069342T3 (da) 2010-08-23
BRPI0718517A2 (pt) 2013-11-19
MEP10709A (en) 2011-12-20
FR2906250A1 (fr) 2008-03-28
CO6160308A2 (es) 2010-05-20
NI200900037A (es) 2014-02-20
EA017442B1 (ru) 2012-12-28
TW200833329A (en) 2008-08-16
EP2069342A1 (fr) 2009-06-17
SV2009003193A (es) 2010-02-01
JO2643B1 (en) 2012-06-17
RS51412B (sr) 2011-02-28
CY1110232T1 (el) 2015-01-14
PE20080671A1 (es) 2008-07-14
PT2069342E (pt) 2010-07-19
PL2069342T3 (pl) 2010-10-29
US7915284B2 (en) 2011-03-29
MY145603A (en) 2012-03-15
AR062897A1 (es) 2008-12-10
WO2008034974A1 (fr) 2008-03-27
CA2662848A1 (fr) 2008-03-27
MX2009002802A (es) 2009-04-01
KR20090054449A (ko) 2009-05-29
JP5336378B2 (ja) 2013-11-06
FR2906250B1 (fr) 2008-10-31
UA95976C2 (en) 2011-09-26
MA30792B1 (fr) 2009-10-01
IL197352A0 (en) 2009-12-24
ES2345016T3 (es) 2010-09-13
GT200900049A (es) 2010-03-04
ME00615B (me) 2011-12-20
CN101516881B (zh) 2012-07-18
TN2009000081A1 (en) 2010-08-19
SI2069342T1 (sl) 2010-09-30
US20090253735A1 (en) 2009-10-08
EP2069342B1 (fr) 2010-05-12

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