NO953457L - Somatostatinpeptider, fremgangsmåte for deres fremstilling, farmasöytiske preparater derav og anvendelse - Google Patents

Somatostatinpeptider, fremgangsmåte for deres fremstilling, farmasöytiske preparater derav og anvendelse

Info

Publication number
NO953457L
NO953457L NO953457A NO953457A NO953457L NO 953457 L NO953457 L NO 953457L NO 953457 A NO953457 A NO 953457A NO 953457 A NO953457 A NO 953457A NO 953457 L NO953457 L NO 953457L
Authority
NO
Norway
Prior art keywords
preparation
pharmaceutical preparations
somatostatin peptides
somatostatin
peptides
Prior art date
Application number
NO953457A
Other languages
English (en)
Other versions
NO953457D0 (no
NO316569B1 (no
Inventor
Rainer Albert
Christian Bruns
Peter Smith-Jones
Barbara Stolz
Gisbert Weckbecker
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of NO953457D0 publication Critical patent/NO953457D0/no
Publication of NO953457L publication Critical patent/NO953457L/no
Publication of NO316569B1 publication Critical patent/NO316569B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/083—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being octreotide or a somatostatin-receptor-binding peptide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO953457A 1994-09-06 1995-09-04 Somatostatinpeptider, farmasøytiske preparater derav, og anvendelse derav, kit for anvendelse ved behandling av somatostatinreseptorpositiv tumorinvasivitet eller symptomer forbundet med tumorvekst, samt farmasøytisk preparat for samme formål NO316569B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9417873A GB9417873D0 (en) 1994-09-06 1994-09-06 Organic compounds

Publications (3)

Publication Number Publication Date
NO953457D0 NO953457D0 (no) 1995-09-04
NO953457L true NO953457L (no) 1996-03-07
NO316569B1 NO316569B1 (no) 2004-02-23

Family

ID=10760870

Family Applications (1)

Application Number Title Priority Date Filing Date
NO953457A NO316569B1 (no) 1994-09-06 1995-09-04 Somatostatinpeptider, farmasøytiske preparater derav, og anvendelse derav, kit for anvendelse ved behandling av somatostatinreseptorpositiv tumorinvasivitet eller symptomer forbundet med tumorvekst, samt farmasøytisk preparat for samme formål

Country Status (31)

Country Link
US (2) US6183721B1 (no)
EP (1) EP0714911B1 (no)
JP (1) JP3054346B2 (no)
KR (1) KR100364111B1 (no)
CN (1) CN1185252C (no)
AT (1) ATE199561T1 (no)
AU (1) AU703057B2 (no)
BR (1) BR9503936A (no)
CA (1) CA2157530C (no)
CO (1) CO4410344A1 (no)
CZ (1) CZ287012B6 (no)
DE (1) DE69520256T2 (no)
DK (1) DK0714911T3 (no)
ES (1) ES2157309T3 (no)
FI (1) FI117424B (no)
GB (1) GB9417873D0 (no)
GR (1) GR3035997T3 (no)
HU (1) HU218284B (no)
IL (1) IL115154A (no)
NO (1) NO316569B1 (no)
NZ (1) NZ272919A (no)
PE (1) PE41496A1 (no)
PL (1) PL182434B1 (no)
PT (1) PT714911E (no)
RU (1) RU2156774C2 (no)
SG (1) SG50356A1 (no)
SI (1) SI0714911T1 (no)
SK (1) SK283774B6 (no)
TR (1) TR199501094A2 (no)
TW (1) TW387898B (no)
ZA (1) ZA957475B (no)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9417873D0 (en) * 1994-09-06 1994-10-26 Sandoz Ltd Organic compounds
AT405906B (de) * 1997-03-14 1999-12-27 Irene Dr Virgolini Radiomarkierte somatostatin rezeptor-liganden zur diagnose und therapie
US6358491B1 (en) 1999-08-27 2002-03-19 Berlex Laboratories, Inc. Somatostatin analogs
PL409579A1 (pl) 2001-02-19 2015-03-02 Novartis Ag Leczenie raka
JP2004529884A (ja) * 2001-02-26 2004-09-30 ブリストル−マイヤーズ・スクイブ・ファーマ・カンパニー 金属放射性医薬のためのアスコルビン酸類似体
JP3996897B2 (ja) * 2001-06-08 2007-10-24 ソシエテ・ドゥ・コンセイユ・ドゥ・ルシェルシュ・エ・ダプリカーション・シャンティフィック・エス・ア・エス ソマトスタチン−ドーパミンキメラ類似体
ITMI20011708A1 (it) * 2001-08-03 2003-02-03 Bracco Imaging Spa Coniugati di peptidi, loro derivati con complessi metallici e utilizzo per i'indagine diagnostica tramite imaging per risonanza magnetica(m
DK1530482T3 (da) 2002-07-18 2014-01-20 Helix Biopharma Corp Brug af urease til at hæmme vækst af cancerceller
US20050118099A1 (en) * 2003-03-10 2005-06-02 Braslawsky Gary R. Thiol-mediated drug attachment to targeting peptides
KR101699142B1 (ko) 2004-06-18 2017-01-23 암브룩스, 인코포레이티드 신규 항원-결합 폴리펩티드 및 이의 용도
EP1831241A2 (en) * 2004-11-24 2007-09-12 AplaGen GmbH Method for solid-phase peptide synthesis and purification
CA2699394C (en) 2007-09-17 2020-03-24 The Regents Of The University Of California Internalizing human monoclonal antibodies targeting prostate cancer cells in situ
AU2012229156A1 (en) 2011-03-11 2013-10-31 Board Of Regents Of The University Of Nebraska Biomarker for coronary artery disease
EP2922578B1 (en) 2012-11-21 2018-12-12 Serene, Llc Tin-117m comprising somatostatin receptor binding compounds
CN103275189B (zh) * 2013-06-06 2014-08-06 深圳翰宇药业股份有限公司 一种用于肽树脂的裂解液及其在固相裂解合成生长抑素中的应用
LT4095130T (lt) * 2013-10-18 2024-04-25 Novartis Ag Žymėti prostatos specifinio membranos antigeno (psma) inhibitoriai, jų naudojimas kaip vizualizavimo medžiagų ir farmacinių medžiagų prostatos vėžiui gydyti
EP3383920B1 (en) 2015-11-30 2024-01-10 The Regents of the University of California Tumor-specific payload delivery and immune activation using a human antibody targeting a highly specific tumor cell surface antigen
ES3015117T3 (en) 2016-08-29 2025-04-29 Fred Hutchinson Cancer Center Chelating platform for delivery of radionuclides
WO2018089829A1 (en) 2016-11-10 2018-05-17 Fortis Therapeutics, Inc. Cd46-specific effector cells and uses thereof
DK3568205T3 (da) 2017-01-12 2023-10-09 Radiomedix Inc Behandling af cancerceller, der overeksprimerer somatostatinreceptorer ved at anvende radioisotop-chelaterede ocreotid-derivater
TW202547563A (zh) * 2018-06-21 2025-12-16 德商愛利穆治療有限公司 用於放射性醫藥之含有體抑素類似物之組成物
TW202015744A (zh) * 2018-06-21 2020-05-01 法商艾普森藥品公司 用於放射性醫藥之含有體抑素類似物之組成物
TW202517302A (zh) 2018-07-25 2025-05-01 法商高級催化劑應用品有限公司 穩定的、濃縮的放射性核種錯合物溶液
US10596276B2 (en) 2018-07-25 2020-03-24 Advanced Accelerator Applications (Italy) S.R.L. Stable, concentrated radionuclide complex solutions
US10596278B2 (en) 2018-07-25 2020-03-24 Advanced Accelerator Applications (Italy) S.R.L. Stable, concentrated radionuclide complex solutions
CN114096264B (zh) 2019-05-20 2025-03-14 因多塞特股份有限公司 制备psma缀合物的方法
EP4192511A1 (en) 2020-08-07 2023-06-14 Fortis Therapeutics, Inc. Immunoconjugates targeting cd46 and methods of use thereof
AU2024339683A1 (en) 2023-09-13 2026-03-26 Toray Industries, Inc. Pharmaceutical composition for treating, preventing and/or diagnosing cancer

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4725577A (en) * 1985-04-25 1988-02-16 Administrators Of The Tulane Educational Fund Biologically active lysine containing octapeptides
US5006643A (en) 1987-06-24 1991-04-09 The Dow Chemical Company Process for preparing isothiocyanato functionalized metal complexes
DE3728600A1 (de) 1987-08-27 1989-03-09 Hoechst Ag Verfahren zur markierung von substanzen mit technetium oder rhenium
AU630362B2 (en) * 1988-05-25 1992-10-29 United States of America, as represented by the Secretary, U.S. Department of Commerce, The Macrocyclic chelates & methods of use thereof
GB9111199D0 (en) * 1991-05-23 1991-07-17 Sandoz Ltd Improvements in or relating to organic compounds
MY106120A (en) * 1988-12-05 1995-03-31 Novartis Ag Peptide derivatives.
EP0494247B1 (en) 1989-09-29 1996-04-03 Neorx Corporation Reducing non-target retention of immunoconjugates and metabolites thereof
WO1993018797A1 (en) * 1992-03-25 1993-09-30 Mallinckrodt Medical, Inc. Method of intraoperatively detecting and locating tumoral tissues
NZ250653A (en) * 1993-01-12 1995-12-21 Sandoz Ltd Somatostatin derivatives and pharmaceutical or diagnostic imaging compositions
US5650134A (en) * 1993-01-12 1997-07-22 Novartis Ag (Formerly Sandoz Ltd.) Peptides
WO1995019187A1 (en) * 1994-01-12 1995-07-20 Amersham International Plc Biological targeting agents
GB9417873D0 (en) * 1994-09-06 1994-10-26 Sandoz Ltd Organic compounds

Also Published As

Publication number Publication date
NO953457D0 (no) 1995-09-04
CN1127259A (zh) 1996-07-24
RU2156774C2 (ru) 2000-09-27
SK108895A3 (en) 1996-06-05
CO4410344A1 (es) 1997-01-09
JP3054346B2 (ja) 2000-06-19
NO316569B1 (no) 2004-02-23
DE69520256D1 (de) 2001-04-12
PL182434B1 (pl) 2002-01-31
US6183721B1 (en) 2001-02-06
KR960010683A (ko) 1996-04-20
ES2157309T3 (es) 2001-08-16
CA2157530C (en) 2007-04-03
GR3035997T3 (en) 2001-09-28
BR9503936A (pt) 1996-09-24
US6277356B1 (en) 2001-08-21
IL115154A (en) 2000-08-13
EP0714911B1 (en) 2001-03-07
HU218284B (en) 2000-07-28
DK0714911T3 (da) 2001-07-09
CZ287012B6 (en) 2000-08-16
FI954147L (fi) 1996-03-07
FI954147A0 (fi) 1995-09-04
NZ272919A (en) 1996-12-20
EP0714911A2 (en) 1996-06-05
SI0714911T1 (en) 2001-08-31
CA2157530A1 (en) 1996-03-07
HUT72895A (en) 1996-06-28
GB9417873D0 (en) 1994-10-26
CN1185252C (zh) 2005-01-19
DE69520256T2 (de) 2001-08-09
HU9502577D0 (en) 1995-11-28
TW387898B (en) 2000-04-21
JPH0881498A (ja) 1996-03-26
IL115154A0 (en) 1995-12-31
FI117424B (fi) 2006-10-13
ZA957475B (en) 1997-03-06
EP0714911A3 (en) 1996-08-21
ATE199561T1 (de) 2001-03-15
AU703057B2 (en) 1999-03-11
AU3041495A (en) 1996-03-21
SG50356A1 (en) 2000-11-21
PL310274A1 (en) 1996-03-18
PE41496A1 (es) 1996-10-14
CZ226395A3 (en) 1996-03-13
SK283774B6 (sk) 2004-01-08
PT714911E (pt) 2001-08-30
KR100364111B1 (ko) 2003-02-05
TR199501094A2 (tr) 1996-06-21

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