NO953457L - Somatostatinpeptider, fremgangsmåte for deres fremstilling, farmasöytiske preparater derav og anvendelse - Google Patents

Somatostatinpeptider, fremgangsmåte for deres fremstilling, farmasöytiske preparater derav og anvendelse

Info

Publication number
NO953457L
NO953457L NO953457A NO953457A NO953457L NO 953457 L NO953457 L NO 953457L NO 953457 A NO953457 A NO 953457A NO 953457 A NO953457 A NO 953457A NO 953457 L NO953457 L NO 953457L
Authority
NO
Norway
Prior art keywords
preparation
pharmaceutical preparations
somatostatin peptides
somatostatin
peptides
Prior art date
Application number
NO953457A
Other languages
English (en)
Other versions
NO953457D0 (no
NO316569B1 (no
Inventor
Rainer Albert
Christian Bruns
Peter Smith-Jones
Barbara Stolz
Gisbert Weckbecker
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of NO953457D0 publication Critical patent/NO953457D0/no
Publication of NO953457L publication Critical patent/NO953457L/no
Publication of NO316569B1 publication Critical patent/NO316569B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/083—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being octreotide or a somatostatin-receptor-binding peptide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Optics & Photonics (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO953457A 1994-09-06 1995-09-04 Somatostatinpeptider, farmasøytiske preparater derav, og anvendelse derav, kit for anvendelse ved behandling av somatostatinreseptorpositiv tumorinvasivitet eller symptomer forbundet med tumorvekst, samt farmasøytisk preparat for samme formål NO316569B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9417873A GB9417873D0 (en) 1994-09-06 1994-09-06 Organic compounds

Publications (3)

Publication Number Publication Date
NO953457D0 NO953457D0 (no) 1995-09-04
NO953457L true NO953457L (no) 1996-03-07
NO316569B1 NO316569B1 (no) 2004-02-23

Family

ID=10760870

Family Applications (1)

Application Number Title Priority Date Filing Date
NO953457A NO316569B1 (no) 1994-09-06 1995-09-04 Somatostatinpeptider, farmasøytiske preparater derav, og anvendelse derav, kit for anvendelse ved behandling av somatostatinreseptorpositiv tumorinvasivitet eller symptomer forbundet med tumorvekst, samt farmasøytisk preparat for samme formål

Country Status (31)

Country Link
US (2) US6183721B1 (no)
EP (1) EP0714911B1 (no)
JP (1) JP3054346B2 (no)
KR (1) KR100364111B1 (no)
CN (1) CN1185252C (no)
AT (1) ATE199561T1 (no)
AU (1) AU703057B2 (no)
BR (1) BR9503936A (no)
CA (1) CA2157530C (no)
CO (1) CO4410344A1 (no)
CZ (1) CZ287012B6 (no)
DE (1) DE69520256T2 (no)
DK (1) DK0714911T3 (no)
ES (1) ES2157309T3 (no)
FI (1) FI117424B (no)
GB (1) GB9417873D0 (no)
GR (1) GR3035997T3 (no)
HU (1) HU218284B (no)
IL (1) IL115154A (no)
NO (1) NO316569B1 (no)
NZ (1) NZ272919A (no)
PE (1) PE41496A1 (no)
PL (1) PL182434B1 (no)
PT (1) PT714911E (no)
RU (1) RU2156774C2 (no)
SG (1) SG50356A1 (no)
SI (1) SI0714911T1 (no)
SK (1) SK283774B6 (no)
TR (1) TR199501094A2 (no)
TW (1) TW387898B (no)
ZA (1) ZA957475B (no)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9417873D0 (en) * 1994-09-06 1994-10-26 Sandoz Ltd Organic compounds
AT405906B (de) * 1997-03-14 1999-12-27 Irene Dr Virgolini Radiomarkierte somatostatin rezeptor-liganden zur diagnose und therapie
US6358491B1 (en) 1999-08-27 2002-03-19 Berlex Laboratories, Inc. Somatostatin analogs
LT2762140T (lt) 2001-02-19 2017-06-26 Novartis Ag Solidinių smegenų navikų gydymas rapamicino dariniu
CZ20032597A3 (cs) * 2001-02-26 2004-12-15 Bristol-Myers Squibb Pharma Company Analogy kyseliny askorbové pro metaloradiofarmaceutika
NZ530007A (en) * 2001-06-08 2006-02-24 Sod Conseils Rech Applic Somatostatin-dopamine chimeric analogues that retain both somatostatin and dopamine activity in vivo and display enhanced biological activity
ITMI20011708A1 (it) * 2001-08-03 2003-02-03 Bracco Imaging Spa Coniugati di peptidi, loro derivati con complessi metallici e utilizzo per i'indagine diagnostica tramite imaging per risonanza magnetica(m
MXPA05000778A (es) 2002-07-18 2005-08-29 Helix Biopharma Corp Uso de ureasa para inhibir el crecimiento de celulas cancerosas.
JP2006522100A (ja) * 2003-03-10 2006-09-28 バイオジェン アイデック インク 標的化ペプチドに対するチオール媒介性薬物結合
CN102532321B (zh) 2004-06-18 2018-10-12 Ambrx公司 新颖抗原结合多肽和其用途
JP2008520616A (ja) * 2004-11-24 2008-06-19 アプラーゲン ゲゼルシャフト ミット ベシュレンクテル ハフツング 固相ペプチド合成および精製方法
EP2192922A4 (en) 2007-09-17 2010-09-29 Univ California INTERNATIONALIZING HUMAN MONOCLONAL ANTIBODIES TO PROMOTE IN SITU ON PROSTATAZELLES
CN105388287A (zh) 2011-03-11 2016-03-09 内布拉斯加大学董事委员会 冠状动脉疾病的生物标志物
EP2922578B1 (en) 2012-11-21 2018-12-12 Serene, Llc Tin-117m comprising somatostatin receptor binding compounds
CN103275189B (zh) * 2013-06-06 2014-08-06 深圳翰宇药业股份有限公司 一种用于肽树脂的裂解液及其在固相裂解合成生长抑素中的应用
EP3456700A1 (en) * 2013-10-18 2019-03-20 Deutsches Krebsforschungszentrum Labeled inhibitors of prostate specific membrane antigen (psma), their use as imaging agents and pharmaceutical agents for the treatment of prostate cancer
ES2975747T3 (es) 2015-11-30 2024-07-12 Univ California Administración de carga útil específica de tumor y activación inmunitaria utilizando un anticuerpo humano que se dirige a un antígeno de superficie celular de tumor altamente específico
WO2018044812A2 (en) 2016-08-29 2018-03-08 Fred Hutchinson Cancer Research Center Chelating platform for delivery of radionuclides
WO2018089829A1 (en) 2016-11-10 2018-05-17 Fortis Therapeutics, Inc. Cd46-specific effector cells and uses thereof
SI3568205T1 (sl) 2017-01-12 2023-12-29 Radiomedix Inc. Zdravljenje rakastih celic, ki prekomerno izražajo receptorje za somatostatin, z uporabo derivatov okreotida, kelatiranih v radioizotope
TW202015744A (zh) 2018-06-21 2020-05-01 法商艾普森藥品公司 用於放射性醫藥之含有體抑素類似物之組成物
TW202547563A (zh) * 2018-06-21 2025-12-16 德商愛利穆治療有限公司 用於放射性醫藥之含有體抑素類似物之組成物
US10596276B2 (en) 2018-07-25 2020-03-24 Advanced Accelerator Applications (Italy) S.R.L. Stable, concentrated radionuclide complex solutions
US20200030466A1 (en) 2018-07-25 2020-01-30 Advanced Accelerator Applications (Italy) Srl Stable, concentrated radionuclide complex solutions
JP7604397B2 (ja) 2019-05-20 2024-12-23 エンドサイト・インコーポレイテッド Ｐｓｍａコンジュゲートの調製方法
AU2021320333A1 (en) 2020-08-07 2023-03-30 Fortis Therapeutics, Inc. Immunoconjugates targeting CD46 and methods of use thereof
WO2025058000A1 (ja) 2023-09-13 2025-03-20 東レ株式会社 癌の治療、予防及び／又は診断用医薬組成物

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4725577A (en) * 1985-04-25 1988-02-16 Administrators Of The Tulane Educational Fund Biologically active lysine containing octapeptides
US5006643A (en) 1987-06-24 1991-04-09 The Dow Chemical Company Process for preparing isothiocyanato functionalized metal complexes
DE3728600A1 (de) 1987-08-27 1989-03-09 Hoechst Ag Verfahren zur markierung von substanzen mit technetium oder rhenium
WO1989011475A1 (en) * 1988-05-25 1989-11-30 The United States Of America, As Represented By Th Macrocyclic chelates and methods of use thereof
GB9111199D0 (en) * 1991-05-23 1991-07-17 Sandoz Ltd Improvements in or relating to organic compounds
MY106120A (en) * 1988-12-05 1995-03-31 Novartis Ag Peptide derivatives.
DE69026387T2 (de) 1989-09-29 1996-11-28 Neorx Corp., Seattle, Wash. Reduktion der nichtzielspezifischen retention von immunokonjugaten und ihren metaboliten
CA2131315A1 (en) * 1992-03-25 1993-09-30 Geert J. Ensing Method of intraoperatively detecting and locating tumoral tissues
US5650134A (en) * 1993-01-12 1997-07-22 Novartis Ag (Formerly Sandoz Ltd.) Peptides
EP0607103A3 (en) * 1993-01-12 1997-07-09 Sandoz Ltd Somatostatin analogs containing chelating groups and their radiolabeled compositions.
CA2179990A1 (en) * 1994-01-12 1995-07-20 Gary Robert Bower Biological targeting agents
GB9417873D0 (en) * 1994-09-06 1994-10-26 Sandoz Ltd Organic compounds

Also Published As

Publication number Publication date
ZA957475B (en) 1997-03-06
SK283774B6 (sk) 2004-01-08
FI954147A0 (fi) 1995-09-04
PE41496A1 (es) 1996-10-14
HU9502577D0 (en) 1995-11-28
EP0714911A2 (en) 1996-06-05
PT714911E (pt) 2001-08-30
NO953457D0 (no) 1995-09-04
AU3041495A (en) 1996-03-21
CA2157530C (en) 2007-04-03
CN1185252C (zh) 2005-01-19
PL310274A1 (en) 1996-03-18
IL115154A (en) 2000-08-13
RU2156774C2 (ru) 2000-09-27
SK108895A3 (en) 1996-06-05
GR3035997T3 (en) 2001-09-28
AU703057B2 (en) 1999-03-11
GB9417873D0 (en) 1994-10-26
PL182434B1 (pl) 2002-01-31
IL115154A0 (en) 1995-12-31
NZ272919A (en) 1996-12-20
CZ226395A3 (en) 1996-03-13
US6183721B1 (en) 2001-02-06
TW387898B (en) 2000-04-21
CO4410344A1 (es) 1997-01-09
ATE199561T1 (de) 2001-03-15
SI0714911T1 (en) 2001-08-31
CZ287012B6 (en) 2000-08-16
FI954147L (fi) 1996-03-07
BR9503936A (pt) 1996-09-24
KR100364111B1 (ko) 2003-02-05
TR199501094A2 (tr) 1996-06-21
JPH0881498A (ja) 1996-03-26
SG50356A1 (en) 2000-11-21
EP0714911B1 (en) 2001-03-07
CA2157530A1 (en) 1996-03-07
JP3054346B2 (ja) 2000-06-19
DE69520256D1 (de) 2001-04-12
DE69520256T2 (de) 2001-08-09
NO316569B1 (no) 2004-02-23
DK0714911T3 (da) 2001-07-09
HU218284B (en) 2000-07-28
EP0714911A3 (en) 1996-08-21
HUT72895A (en) 1996-06-28
ES2157309T3 (es) 2001-08-16
FI117424B (fi) 2006-10-13
CN1127259A (zh) 1996-07-24
KR960010683A (ko) 1996-04-20
US6277356B1 (en) 2001-08-21

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