NO995040L - 5-aryl-3-(8-azabicyklo(3.2.2)okt-3-yl)-1,3,4-oksadiazol-2(3H)- on-derivater som 5-HT4 reseptorligander - Google Patents

5-aryl-3-(8-azabicyklo(3.2.2)okt-3-yl)-1,3,4-oksadiazol-2(3H)- on-derivater som 5-HT4 reseptorligander

Info

Publication number
NO995040L
NO995040L NO995040A NO995040A NO995040L NO 995040 L NO995040 L NO 995040L NO 995040 A NO995040 A NO 995040A NO 995040 A NO995040 A NO 995040A NO 995040 L NO995040 L NO 995040L
Authority
NO
Norway
Prior art keywords
oxadiazol
azabicyclo
oct
aryl
derivatives
Prior art date
Application number
NO995040A
Other languages
English (en)
Norwegian (no)
Other versions
NO995040D0 (no
Inventor
Samir Jegham
Alistair Lochead
Frederic Galli
Alain Nedelec
Axelle Samson
Thierry Gallet
Original Assignee
Sanofi Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Synthelabo filed Critical Sanofi Synthelabo
Publication of NO995040D0 publication Critical patent/NO995040D0/no
Publication of NO995040L publication Critical patent/NO995040L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO995040A 1997-04-18 1999-10-15 5-aryl-3-(8-azabicyklo(3.2.2)okt-3-yl)-1,3,4-oksadiazol-2(3H)- on-derivater som 5-HT4 reseptorligander NO995040L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9704802A FR2762316B1 (fr) 1997-04-18 1997-04-18 Derives de 5-aryl-3-(8-azabicyclo[3.2.1] octan-3-yl)-1,3,4- oxadiazol-2(3h)-one, leur preparation et leur application en therapeutique
PCT/FR1998/000754 WO1998047898A1 (fr) 1997-04-18 1998-04-15 Derives de 5-aryl-3-(8-azabicyclo(3.2.2)oct-3-yl)-1,3,4-oxadiazol-2(3h)-one en tant que ligands des recepteurs 5-ht4

Publications (2)

Publication Number Publication Date
NO995040D0 NO995040D0 (no) 1999-10-15
NO995040L true NO995040L (no) 1999-12-16

Family

ID=9506076

Family Applications (1)

Application Number Title Priority Date Filing Date
NO995040A NO995040L (no) 1997-04-18 1999-10-15 5-aryl-3-(8-azabicyklo(3.2.2)okt-3-yl)-1,3,4-oksadiazol-2(3H)- on-derivater som 5-HT4 reseptorligander

Country Status (32)

Country Link
US (1) US6255319B1 (de)
EP (1) EP0975631B1 (de)
JP (1) JP2001521542A (de)
KR (1) KR20010006452A (de)
CN (1) CN1260794A (de)
AR (1) AR012458A1 (de)
AT (1) ATE206424T1 (de)
AU (1) AU742666B2 (de)
BG (1) BG64053B1 (de)
BR (1) BR9808926A (de)
CA (1) CA2286106A1 (de)
CO (1) CO4750656A1 (de)
CZ (1) CZ289154B6 (de)
DE (1) DE69801905T2 (de)
DK (1) DK0975631T3 (de)
EE (1) EE03769B1 (de)
ES (1) ES2165162T3 (de)
FR (1) FR2762316B1 (de)
HU (1) HUP0002456A3 (de)
IL (1) IL132352A0 (de)
NO (1) NO995040L (de)
NZ (1) NZ500396A (de)
PL (1) PL186894B1 (de)
PT (1) PT975631E (de)
RU (1) RU2186066C2 (de)
SI (1) SI0975631T1 (de)
SK (1) SK283441B6 (de)
TR (1) TR199902600T2 (de)
TW (1) TW502005B (de)
UA (1) UA57071C2 (de)
WO (1) WO1998047898A1 (de)
ZA (1) ZA983257B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0211230D0 (en) * 2002-05-16 2002-06-26 Medinnova Sf Treatment of heart failure
ATE474577T1 (de) * 2003-03-26 2010-08-15 Merck Sharp & Dohme Bicyclische piperidin-derivate als melanocortin-4 rezeptor-agonisten
US7321042B2 (en) * 2003-10-16 2008-01-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Process for preparing N-substituted 3-β-aminonortropanes
BRPI0416691A (pt) * 2003-11-18 2007-01-30 Boehringer Ingelheim Int forma de preparação farmacêutica sólida
EA200801607A1 (ru) 2004-06-15 2008-10-30 Пфайзер Инк. Производные бензимидазолонкарбоновой кислоты
US7737163B2 (en) 2004-06-15 2010-06-15 Pfizer Inc. Benzimidazolone carboxylic acid derivatives
FR2873693B1 (fr) * 2004-07-29 2006-09-15 Sanofi Synthelabo Derives d'amino-tropane, leur preparation et leur application en therapeutique
ATE469897T1 (de) * 2004-12-22 2010-06-15 Theravance Inc Indazolcarbonsäureamidverbindungen
SE532388C2 (sv) * 2008-03-14 2010-01-12 Tetra Laval Holdings & Finance Förpackningslaminat och -behållare med två separata gasbarriärskikt samt metod för deras framställning
ES2657989T3 (es) * 2013-03-15 2018-03-07 Monsanto Technology Llc Azoles n-, c-disustituidos para controlar plagas de nematodos
GB201814151D0 (en) * 2018-08-31 2018-10-17 Ucl Business Plc Compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5055476A (en) * 1990-08-13 1991-10-08 Hoechst-Roussel Pharmaceuticals Incorporated 3-(1,2-benzisoxazol-3-yl)-4-pyridinamines and derivatives
ES2135414T3 (es) * 1991-09-12 1999-11-01 Smithkline Beecham Plc Antagonistas del receptor 5-ht4.
PH31171A (en) * 1992-02-04 1998-03-20 Esai Co Ltd Aminobenzonic acid derivatives useful for treatinggastrointestinal conditions.
CA2129112A1 (en) * 1992-02-06 1993-08-19 Francis David King Benzopyran, benzothiopyran and benzofuran derivatives as 5-ht4 antagonists
JP3235913B2 (ja) * 1993-07-30 2001-12-04 エーザイ株式会社 アミノ安息香酸誘導体
JP4263240B2 (ja) * 1995-11-09 2009-05-13 サノフィ−アベンティス ５−フェニル−３−（ピペリジン−４−イル）−１，３，４−オキサジアゾール−２（３ｈ）−オン誘導体、及びその５−ｈｔ４又はｈ３レセプターリガンドとしての用途

Also Published As

Publication number Publication date
DE69801905D1 (de) 2001-11-08
WO1998047898A1 (fr) 1998-10-29
TR199902600T2 (xx) 2000-03-21
PL186894B1 (pl) 2004-03-31
AR012458A1 (es) 2000-10-18
ATE206424T1 (de) 2001-10-15
DK0975631T3 (da) 2002-01-28
RU2186066C2 (ru) 2002-07-27
DE69801905T2 (de) 2002-07-04
BG103810A (en) 2000-06-30
SK283441B6 (sk) 2003-07-01
CA2286106A1 (en) 1998-10-29
FR2762316B1 (fr) 1999-12-17
SI0975631T1 (en) 2002-06-30
CN1260794A (zh) 2000-07-19
CO4750656A1 (es) 1999-03-31
FR2762316A1 (fr) 1998-10-23
BG64053B1 (bg) 2003-11-28
US6255319B1 (en) 2001-07-03
CZ364199A3 (cs) 2000-03-15
AU742666B2 (en) 2002-01-10
PL336315A1 (en) 2000-06-19
BR9808926A (pt) 2000-08-01
KR20010006452A (ko) 2001-01-26
AU7341598A (en) 1998-11-13
SK142699A3 (en) 2000-05-16
ZA983257B (en) 1998-10-19
EE9900487A (et) 2000-06-15
JP2001521542A (ja) 2001-11-06
CZ289154B6 (cs) 2001-11-14
NZ500396A (en) 2001-04-27
PT975631E (pt) 2002-03-28
IL132352A0 (en) 2001-03-19
NO995040D0 (no) 1999-10-15
EP0975631A1 (de) 2000-02-02
TW502005B (en) 2002-09-11
EE03769B1 (et) 2002-06-17
ES2165162T3 (es) 2002-03-01
HUP0002456A3 (en) 2001-03-28
EP0975631B1 (de) 2001-10-04
UA57071C2 (uk) 2003-06-16
HUP0002456A2 (hu) 2000-12-28

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