PL121492B1 - Process for preparing novel salts of bis-tetrahydroisoquinolinium-alkyl m-or p-phenylene-dialkanocarboxylatessilanov bis-tetragidroizokhinolino-alkilovykh solejj - Google Patents

Process for preparing novel salts of bis-tetrahydroisoquinolinium-alkyl m-or p-phenylene-dialkanocarboxylatessilanov bis-tetragidroizokhinolino-alkilovykh solejj Download PDF

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Publication number
PL121492B1
PL121492B1 PL1978208757A PL20875778A PL121492B1 PL 121492 B1 PL121492 B1 PL 121492B1 PL 1978208757 A PL1978208757 A PL 1978208757A PL 20875778 A PL20875778 A PL 20875778A PL 121492 B1 PL121492 B1 PL 121492B1
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PL
Poland
Prior art keywords
och
formula
och3
salt
coo
Prior art date
Application number
PL1978208757A
Other languages
English (en)
Polish (pl)
Other versions
PL208757A1 (pl
Inventor
Jdm J Sararese
Richard J Kitz
Sara Ginsburg
Original Assignee
Massachusetts Gen Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Gen Hospital filed Critical Massachusetts Gen Hospital
Publication of PL208757A1 publication Critical patent/PL208757A1/xx
Publication of PL121492B1 publication Critical patent/PL121492B1/pl

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C07D217/20—Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PL1978208757A 1977-08-01 1978-07-31 Process for preparing novel salts of bis-tetrahydroisoquinolinium-alkyl m-or p-phenylene-dialkanocarboxylatessilanov bis-tetragidroizokhinolino-alkilovykh solejj PL121492B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82079477A 1977-08-01 1977-08-01

Publications (2)

Publication Number Publication Date
PL208757A1 PL208757A1 (pl) 1979-06-04
PL121492B1 true PL121492B1 (en) 1982-05-31

Family

ID=25231743

Family Applications (1)

Application Number Title Priority Date Filing Date
PL1978208757A PL121492B1 (en) 1977-08-01 1978-07-31 Process for preparing novel salts of bis-tetrahydroisoquinolinium-alkyl m-or p-phenylene-dialkanocarboxylatessilanov bis-tetragidroizokhinolino-alkilovykh solejj

Country Status (21)

Country Link
JP (1) JPS5455577A (fr)
AT (1) AT368496B (fr)
AU (1) AU523706B2 (fr)
BE (1) BE869415A (fr)
CA (1) CA1113096A (fr)
DD (1) DD143254A5 (fr)
DE (1) DE2833505A1 (fr)
DK (1) DK339078A (fr)
ES (1) ES472229A1 (fr)
FI (1) FI782363A7 (fr)
FR (1) FR2399429A1 (fr)
GB (1) GB2002758B (fr)
IE (1) IE47014B1 (fr)
IL (1) IL55254A (fr)
LU (1) LU80062A1 (fr)
MC (1) MC1197A1 (fr)
NL (1) NL7808067A (fr)
PL (1) PL121492B1 (fr)
SE (1) SE7808267L (fr)
SU (1) SU862820A3 (fr)
ZA (1) ZA784331B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1125287A (fr) * 1978-07-21 1982-06-08 John J. Savarese Modes d'emploi de substances a base de bis-isoquinolinium
US4235906A (en) 1978-07-21 1980-11-25 Massachusetts General Hospital Bis-isoquinolinium compounds, compositions and methods of use
JPS5645459A (en) * 1979-09-20 1981-04-25 Otsuka Pharmaceut Co Ltd Cyclic amine
JPS5899465A (ja) * 1981-11-23 1983-06-13 ザ・ウエルカム・フアウンデ−シヨン・リミテツド イソキノリン誘導体
GB8418303D0 (en) * 1984-07-18 1984-08-22 Wellcome Found Compounds
JPH0555438A (ja) * 1991-08-26 1993-03-05 Rohm Co Ltd 電子部品のリード端子構造
ATE295351T1 (de) * 1997-03-25 2005-05-15 Avera Pharmaceuticals Inc Substituierte isochinoline als ultra kurz wirkende neuromuskuläre blocker
AU2007328210B2 (en) * 2006-12-06 2012-11-22 Cornell Research Foundation, Inc. Intermediate duration neuromuscular blocking agents and antagonists thereof
WO2010107488A1 (fr) 2009-03-17 2010-09-23 Cornell University Agents de blocage neuromusculaires non dépolarisants réversibles et leur méthode
WO2011022491A1 (fr) 2009-08-19 2011-02-24 Cornell University Cystéine pour injection physiologique
CN114057642B (zh) * 2021-12-10 2023-03-28 广东嘉博制药有限公司 一种米库氯铵中间体的合成方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5156762U (fr) * 1974-10-28 1976-05-04

Also Published As

Publication number Publication date
ATA555478A (de) 1982-02-15
GB2002758B (en) 1982-02-03
IL55254A0 (en) 1978-09-29
CA1113096A (fr) 1981-11-24
MC1197A1 (fr) 1979-03-19
AT368496B (de) 1982-10-11
ZA784331B (en) 1979-12-27
AU3847678A (en) 1980-02-07
IE47014B1 (en) 1983-11-30
DE2833505A1 (de) 1979-04-05
FR2399429A1 (fr) 1979-03-02
BE869415A (fr) 1979-01-31
PL208757A1 (pl) 1979-06-04
GB2002758A (en) 1979-02-28
ES472229A1 (es) 1979-03-16
DD143254A5 (de) 1980-08-13
IE781550L (en) 1979-02-01
DK339078A (da) 1979-02-02
SU862820A3 (ru) 1981-09-07
IL55254A (en) 1983-03-31
FI782363A7 (fi) 1979-02-02
JPS5455577A (en) 1979-05-02
AU523706B2 (en) 1982-08-12
LU80062A1 (fr) 1979-05-15
SE7808267L (sv) 1979-02-02
NL7808067A (nl) 1979-02-05
FR2399429B1 (fr) 1981-07-17

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