|
USRE47770E1
(en)
|
2002-07-18 |
2019-12-17 |
Merus N.V. |
Recombinant production of mixtures of antibodies
|
|
NZ537277A
(en)
|
2002-07-18 |
2008-04-30 |
Crucell Holland Bv |
Recombinant production of mixtures of antibodies
|
|
WO2004106375A1
(en)
|
2003-05-30 |
2004-12-09 |
Merus Biopharmaceuticals B.V. I.O. |
Fab library for the preparation of anti vegf and anti rabies virus fabs
|
|
US20100069614A1
(en)
|
2008-06-27 |
2010-03-18 |
Merus B.V. |
Antibody producing non-human mammals
|
|
KR101374454B1
(ko)
|
2005-03-31 |
2014-03-17 |
추가이 세이야쿠 가부시키가이샤 |
회합제어에 의한 폴리펩티드 제조방법
|
|
JP5144499B2
(ja)
|
2006-03-31 |
2013-02-13 |
中外製薬株式会社 |
二重特異性抗体を精製するための抗体改変方法
|
|
EP4793360A2
(en)
|
2006-03-31 |
2026-08-19 |
Chugai Seiyaku Kabushiki Kaisha |
Methods for controlling blood pharmacokinetics of antibodies
|
|
HRP20160082T1
(hr)
|
2006-09-29 |
2016-02-26 |
Oncomed Pharmaceuticals, Inc. |
Sastavi i postupci za dijagnosticiranje i lijeäśenje raka
|
|
CA2686827C
(en)
|
2006-12-14 |
2014-09-16 |
Aileron Therapeutics, Inc. |
Bis-sulfhydryl macrocyclization systems
|
|
CN109627287A
(zh)
|
2007-02-23 |
2019-04-16 |
爱勒让治疗公司 |
三唑大环系统
|
|
EP2508531B1
(en)
|
2007-03-28 |
2016-10-19 |
President and Fellows of Harvard College |
Stitched polypeptides
|
|
EP2626372B1
(en)
|
2007-03-29 |
2018-03-21 |
Genmab A/S |
Bispecific antibodies and methods for production thereof
|
|
ES2687808T3
(es)
|
2007-09-26 |
2018-10-29 |
Chugai Seiyaku Kabushiki Kaisha |
Región constante de anticuerpo modificado
|
|
EP3127921A1
(en)
|
2007-09-26 |
2017-02-08 |
Chugai Seiyaku Kabushiki Kaisha |
Method of modifying isoelectric point of antibody via amino acid substition in cdr
|
|
US20090162359A1
(en)
|
2007-12-21 |
2009-06-25 |
Christian Klein |
Bivalent, bispecific antibodies
|
|
EP3663318A1
(en)
*
|
2008-01-07 |
2020-06-10 |
Amgen Inc. |
Method for making antibody fc-heterodimeric molecules using electrostatic steering effects
|
|
EP2282769A4
(en)
|
2008-04-29 |
2012-04-25 |
Abbott Lab |
DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND ITS USES
|
|
EP2297209A4
(en)
|
2008-06-03 |
2012-08-01 |
Abbott Lab |
IMMUNOGLOBULINS WITH TWO VARIABLE DOMAINS AND USES THEREOF
|
|
EP2315602A4
(en)
|
2008-06-26 |
2011-11-02 |
Acceleron Pharma Inc |
METHOD OF DOSING AN ACTRIIB ANTAGONIST AND MONITORING TREATED PATIENTS
|
|
US8822645B2
(en)
|
2008-07-08 |
2014-09-02 |
Abbvie Inc. |
Prostaglandin E2 dual variable domain immunoglobulins and uses thereof
|
|
WO2010019702A2
(en)
|
2008-08-12 |
2010-02-18 |
Oncomed Pharmaceuticals, Inc. |
Ddr1-binding agents and methods of use thereof
|
|
EP2376100B1
(en)
|
2009-01-14 |
2017-10-25 |
Aileron Therapeutics, Inc. |
Peptidomimetic macrocycles
|
|
WO2010085495A1
(en)
|
2009-01-21 |
2010-07-29 |
Amgen Inc. |
Compositions and methods of treating inflammatory and autoimmune diseases
|
|
CN104262483A
(zh)
*
|
2009-01-26 |
2015-01-07 |
根马布股份公司 |
用于生成抗体混合物的方法
|
|
TWI544077B
(zh)
|
2009-03-19 |
2016-08-01 |
中外製藥股份有限公司 |
Antibody constant region change body
|
|
JP5717624B2
(ja)
|
2009-03-19 |
2015-05-13 |
中外製薬株式会社 |
抗体定常領域改変体
|
|
CN103755808B
(zh)
|
2009-03-25 |
2016-02-10 |
霍夫曼-拉罗奇有限公司 |
抗-α5β1抗体及其应用
|
|
PT2417156E
(pt)
|
2009-04-07 |
2015-04-29 |
Roche Glycart Ag |
Anticorpos trivalentes, biespecíficos
|
|
AU2013203859B2
(en)
*
|
2009-04-27 |
2016-09-08 |
Oncomed Pharmaceuticals, Inc. |
Method for making heteromultimeric molecules
|
|
US9067986B2
(en)
*
|
2009-04-27 |
2015-06-30 |
Oncomed Pharmaceuticals, Inc. |
Method for making heteromultimeric molecules
|
|
US9676845B2
(en)
|
2009-06-16 |
2017-06-13 |
Hoffmann-La Roche, Inc. |
Bispecific antigen binding proteins
|
|
TWI507525B
(zh)
|
2009-06-26 |
2015-11-11 |
Regeneron Pharma |
具天然免疫球蛋白形式之易分離的雙專一性抗體
|
|
CA2766166A1
(en)
|
2009-07-08 |
2011-01-13 |
Amgen Inc. |
Design of stable and aggregation free antibody fc molecules through ch3 domain interface engineering
|
|
TW201109438A
(en)
*
|
2009-07-29 |
2011-03-16 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
|
US9493578B2
(en)
|
2009-09-02 |
2016-11-15 |
Xencor, Inc. |
Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
|
|
CN102712696A
(zh)
|
2009-09-16 |
2012-10-03 |
弗·哈夫曼-拉罗切有限公司 |
包含卷曲螺旋和/或系链的蛋白质复合体及其用途
|
|
CA2774973A1
(en)
|
2009-09-22 |
2011-03-31 |
Aileron Therapeutics, Inc. |
Peptidomimetic macrocycles
|
|
US10150808B2
(en)
|
2009-09-24 |
2018-12-11 |
Chugai Seiyaku Kabushiki Kaisha |
Modified antibody constant regions
|
|
AR078651A1
(es)
|
2009-10-15 |
2011-11-23 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
|
EP3485908B1
(en)
|
2009-10-16 |
2021-08-18 |
Mereo BioPharma 5, Inc. |
Therapeutic combination and use of dll4 antagonist antibodies and anti-hypertensive agents
|
|
UY32979A
(es)
|
2009-10-28 |
2011-02-28 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
|
EP2504360B1
(en)
*
|
2009-11-23 |
2018-08-15 |
Amgen Inc. |
Monomeric antibody fc
|
|
US20130089554A1
(en)
*
|
2009-12-29 |
2013-04-11 |
Emergent Product Development Seattle, Llc |
RON Binding Constructs and Methods of Use Thereof
|
|
SG183149A1
(en)
|
2010-02-08 |
2012-09-27 |
Regeneron Pharma |
Common light chain mouse
|
|
US20130045492A1
(en)
|
2010-02-08 |
2013-02-21 |
Regeneron Pharmaceuticals, Inc. |
Methods For Making Fully Human Bispecific Antibodies Using A Common Light Chain
|
|
US9796788B2
(en)
|
2010-02-08 |
2017-10-24 |
Regeneron Pharmaceuticals, Inc. |
Mice expressing a limited immunoglobulin light chain repertoire
|
|
ES2519348T3
(es)
|
2010-02-18 |
2014-11-06 |
Genentech, Inc. |
Antagonistas de neurregulina y uso de los mismos en el tratamiento del cáncer
|
|
EP2543730B1
(en)
|
2010-03-04 |
2018-10-31 |
Chugai Seiyaku Kabushiki Kaisha |
Antibody constant region variant
|
|
KR101899835B1
(ko)
|
2010-03-24 |
2018-09-19 |
제넨테크, 인크. |
항-lrp6 항체
|
|
CN103119054B
(zh)
|
2010-03-26 |
2017-01-18 |
达特茅斯大学理事会 |
Vista调节性t细胞介体蛋白、vista结合剂及其用途
|
|
US20150231215A1
(en)
|
2012-06-22 |
2015-08-20 |
Randolph J. Noelle |
VISTA Antagonist and Methods of Use
|
|
TW201138821A
(en)
|
2010-03-26 |
2011-11-16 |
Roche Glycart Ag |
Bispecific antibodies
|
|
US10745467B2
(en)
|
2010-03-26 |
2020-08-18 |
The Trustees Of Dartmouth College |
VISTA-Ig for treatment of autoimmune, allergic and inflammatory disorders
|
|
WO2011127418A1
(en)
|
2010-04-09 |
2011-10-13 |
Amgen Inc. |
Btnl9 proteins, nucleic acids, and antibodies and uses thereof
|
|
AU2013203221B2
(en)
*
|
2010-04-20 |
2016-06-02 |
Genmab A/S |
Heterodimeric antibody FC-containing proteins and methods for production thereof
|
|
JP2019048814A
(ja)
*
|
2010-04-20 |
2019-03-28 |
ゲンマブ エー/エス |
ヘテロ二量体抗体Fc含有タンパク質およびその産生方法
|
|
PT2560993T
(pt)
|
2010-04-20 |
2024-09-16 |
Genmab As |
Proteínas contendo anticorpo heterodimérico fc e métodos para a produção das mesmas
|
|
AU2016219622A1
(en)
*
|
2010-04-20 |
2016-09-15 |
Genmab A/S |
Heterodimeric antibody FC-containing proteins and methods for production thereof
|
|
WO2011133886A2
(en)
|
2010-04-23 |
2011-10-27 |
Genentech, Inc. |
Production of heteromultimeric proteins
|
|
WO2011143545A1
(en)
|
2010-05-14 |
2011-11-17 |
Rinat Neuroscience Corporation |
Heterodimeric proteins and methods for producing and purifying them
|
|
WO2011147834A1
(en)
|
2010-05-26 |
2011-12-01 |
Roche Glycart Ag |
Antibodies against cd19 and uses thereof
|
|
IL299365A
(en)
|
2010-05-27 |
2023-02-01 |
Genmab As |
Monoclonal antibodies against 2HER
|
|
CN103080136B
(zh)
|
2010-06-18 |
2015-08-12 |
霍夫曼-拉罗奇有限公司 |
抗Axl抗体及使用方法
|
|
WO2011161119A1
(en)
|
2010-06-22 |
2011-12-29 |
F. Hoffmann-La Roche Ag |
Antibodies against insulin-like growth factor i receptor and uses thereof
|
|
WO2011161189A1
(en)
|
2010-06-24 |
2011-12-29 |
F. Hoffmann-La Roche Ag |
Anti-hepsin antibodies and methods of use
|
|
NZ605449A
(en)
|
2010-07-09 |
2015-03-27 |
Genentech Inc |
Anti-neuropilin antibodies and methods of use
|
|
CN104634971A
(zh)
|
2010-07-19 |
2015-05-20 |
霍夫曼-拉罗奇有限公司 |
鉴定响应抗癌疗法的可能性升高的患者的方法
|
|
WO2012010549A1
(en)
|
2010-07-19 |
2012-01-26 |
F. Hoffmann-La Roche Ag |
Method to identify a patient with an increased likelihood of responding to an anti-cancer therapy
|
|
WO2012010582A1
(en)
|
2010-07-21 |
2012-01-26 |
Roche Glycart Ag |
Anti-cxcr5 antibodies and methods of use
|
|
EP2598530A2
(en)
|
2010-07-29 |
2013-06-05 |
Xencor, Inc. |
Antibodies with modified isoelectric points
|
|
KR20130100118A
(ko)
|
2010-08-03 |
2013-09-09 |
아비에 인코포레이티드 |
이원 가변 도메인 면역글로불린 및 이의 용도
|
|
KR20130045914A
(ko)
|
2010-08-03 |
2013-05-06 |
에프. 호프만-라 로슈 아게 |
만성 림프구성 백혈병(cll) 생체지표
|
|
BR112013002532A2
(pt)
|
2010-08-05 |
2016-05-31 |
Hoffmann La Roche |
proteína de fusão de citocina anti-viral do anticorpo anti-mhc
|
|
BR112013002444A2
(pt)
|
2010-08-13 |
2016-05-24 |
Roche Glycart Ag |
anticorpo, polinucleotídeo e polipeotídeo isolados, composição, vetor, cécula hospedeira, conjulgado de anticorpo, formulação farmacêutica, uso do anticorpo, métodos para produzir um anticorpo, tratar um indivíduo, induzir a lise celular de uma célula tumorosa e diagnosticar uma doença em um indivíduo
|
|
PE20171512A1
(es)
|
2010-08-13 |
2017-10-20 |
Roche Glycart Ag |
Anticuerpos anti-fap
|
|
SI2603600T1
(sl)
|
2010-08-13 |
2019-04-30 |
Aileron Therapeutics, Inc. |
Peptidomimetični makrocikli
|
|
KR101603001B1
(ko)
|
2010-08-25 |
2016-03-11 |
에프. 호프만-라 로슈 아게 |
Il-18r1에 대한 항체 및 그의 용도
|
|
US9046513B2
(en)
|
2010-08-26 |
2015-06-02 |
Abbvie Inc. |
Dual variable domain immunoglobulins and uses thereof
|
|
SG10201408229WA
(en)
|
2010-08-31 |
2015-02-27 |
Genentech Inc |
Biomarkers and methods of treatment
|
|
US8551479B2
(en)
|
2010-09-10 |
2013-10-08 |
Oncomed Pharmaceuticals, Inc. |
Methods for treating melanoma
|
|
CN103429620B
(zh)
*
|
2010-11-05 |
2018-03-06 |
酵活有限公司 |
在Fc结构域中具有突变的稳定异源二聚的抗体设计
|
|
AU2011326564A1
(en)
|
2010-11-10 |
2013-05-09 |
Genentech, Inc. |
Methods and compositions for neural disease immunotherapy
|
|
CN105859889B
(zh)
|
2010-11-17 |
2020-01-07 |
中外制药株式会社 |
具有代替凝血因子viii的功能的功能的多特异性抗原结合分子
|
|
WO2012069466A1
(en)
|
2010-11-24 |
2012-05-31 |
Novartis Ag |
Multispecific molecules
|
|
TWI736437B
(zh)
|
2010-11-30 |
2021-08-11 |
日商中外製藥股份有限公司 |
細胞傷害誘導治療劑
|
|
CN103443125B
(zh)
|
2010-11-30 |
2019-05-03 |
霍夫曼-拉罗奇有限公司 |
低亲和力血脑屏障受体抗体及其用途
|
|
KR101615420B1
(ko)
|
2010-12-16 |
2016-04-26 |
제넨테크, 인크. |
Th2 억제에 관한 진단 및 치료
|
|
AU2011349443B2
(en)
|
2010-12-20 |
2015-12-24 |
Genentech, Inc. |
Anti-mesothelin antibodies and immunoconjugates
|
|
CN103261230A
(zh)
|
2010-12-22 |
2013-08-21 |
霍夫曼-拉罗奇有限公司 |
抗pcsk9抗体及使用方法
|
|
US10689447B2
(en)
|
2011-02-04 |
2020-06-23 |
Genentech, Inc. |
Fc variants and methods for their production
|
|
AR085138A1
(es)
|
2011-02-04 |
2013-09-11 |
Genentech Inc |
VARIANTES DE Fc Y METODOS PARA SU PRODUCCION
|
|
CN105440123B
(zh)
|
2011-02-10 |
2020-10-09 |
罗切格利卡特公司 |
突变体白介素-2多肽
|
|
JP5768147B2
(ja)
|
2011-02-28 |
2015-08-26 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
一価抗原結合タンパク質
|
|
WO2012116926A1
(en)
|
2011-02-28 |
2012-09-07 |
F. Hoffmann-La Roche Ag |
Antigen binding proteins
|
|
AU2012222833B2
(en)
|
2011-03-03 |
2017-03-16 |
Zymeworks Inc. |
Multivalent heteromultimer scaffold design and constructs
|
|
WO2012125850A1
(en)
|
2011-03-16 |
2012-09-20 |
Amgen Inc. |
Fc variants
|
|
JP2014511836A
(ja)
|
2011-03-25 |
2014-05-19 |
グレンマーク ファーマシューティカルズ, エセ.アー. |
ヘテロ二量体免疫グロブリン
|
|
LT2691417T
(lt)
|
2011-03-29 |
2018-10-25 |
Roche Glycart Ag |
Antikūno fc variantai
|
|
CA2828890A1
(en)
|
2011-04-07 |
2012-10-11 |
Genentech, Inc. |
Anti-fgfr4 antibodies and methods of use
|
|
JP5977814B2
(ja)
|
2011-04-08 |
2016-08-24 |
アムジエン・インコーポレーテツド |
増殖分化因子15(gdf−15)を使用して代謝障害を治療または改善する方法
|
|
EP3415528B1
(en)
|
2011-04-13 |
2021-05-26 |
Bristol-Myers Squibb Company |
Fc fusion proteins comprising novel linkers or arrangements
|
|
WO2012143524A2
(en)
|
2011-04-20 |
2012-10-26 |
Genmab A/S |
Bispecific antibodies against her2 and cd3
|
|
RU2013150331A
(ru)
|
2011-04-20 |
2015-05-27 |
Рош Гликарт Аг |
СПОСОБ И УСТРОЙСТВА ДЛЯ рН-ЗАВИСИМОГО ПРОХОЖДЕНИЯ ГЕМАТОЭНЦЕФАЛИЧЕСКОГО БАРЬЕРА
|
|
CA2832387A1
(en)
*
|
2011-04-20 |
2012-10-26 |
Genmab A/S |
Bispecifc antibodies against her2
|
|
EP2699260B1
(en)
|
2011-04-20 |
2024-11-20 |
Genmab A/S |
Bispecifc antibodies against her2
|
|
EA201892619A1
(ru)
|
2011-04-29 |
2019-04-30 |
Роше Гликарт Аг |
Иммуноконъюгаты, содержащие мутантные полипептиды интерлейкина-2
|
|
EP2707723B1
(en)
|
2011-05-12 |
2016-02-10 |
Genentech, Inc. |
Multiple reaction monitoring lc-ms/ms method to detect therapeutic antibodies in animal samples using framework signature pepides
|
|
WO2012158704A1
(en)
|
2011-05-16 |
2012-11-22 |
Genentech, Inc. |
Fgfr1 agonists and methods of use
|
|
WO2012171996A1
(en)
|
2011-06-15 |
2012-12-20 |
F. Hoffmann-La Roche Ag |
Anti-human epo receptor antibodies and methods of use
|
|
RU2013155695A
(ru)
|
2011-06-30 |
2015-08-10 |
Дженентек, Инк. |
Препараты антител против с-мет
|
|
WO2013002362A1
(ja)
*
|
2011-06-30 |
2013-01-03 |
中外製薬株式会社 |
ヘテロ二量化ポリペプチド
|
|
UA117901C2
(uk)
|
2011-07-06 |
2018-10-25 |
Ґенмаб Б.В. |
Спосіб посилення ефекторної функції вихідного поліпептиду, його варіанти та їх застосування
|
|
EP2543680A1
(en)
*
|
2011-07-07 |
2013-01-09 |
Centre National de la Recherche Scientifique |
Multispecific mutated antibody Fab fragments
|
|
AU2012286048A1
(en)
|
2011-07-18 |
2014-02-20 |
Arts Biologics A/S |
Long acting luteinizing hormone (LH) compound
|
|
PH12014500220A1
(en)
*
|
2011-07-27 |
2019-03-22 |
Glaxo Group Ltd |
Anti-vegf single variable domains fused to fc domains
|
|
ES2872081T3
(es)
|
2011-08-05 |
2021-11-02 |
Regeneron Pharma |
Ratones con cadena ligera universal humanizada
|
|
BR112014003431A2
(pt)
|
2011-08-17 |
2017-06-13 |
Genentech Inc |
anticorpo, ácido nucleico, célula hospedeira, método de produção de um anticorpo, imunoconjugado, formulação farmacêutica, agente farmacêutico, uso do anticorpo, método de tratamento de um indivíduo que tem câncer e método de aumento de tempo para recorrência de tumor
|
|
JP2014534806A
(ja)
|
2011-08-23 |
2014-12-25 |
ロシュ グリクアート アーゲー |
抗mcsp抗体
|
|
KR101870555B1
(ko)
|
2011-08-23 |
2018-06-22 |
로슈 글리카트 아게 |
T 세포 활성화 항원 및 종양 항원에 대해 특이적인 이중특이적 항체 및 이의 사용 방법
|
|
WO2013026837A1
(en)
|
2011-08-23 |
2013-02-28 |
Roche Glycart Ag |
Bispecific t cell activating antigen binding molecules
|
|
KR101721301B1
(ko)
|
2011-08-23 |
2017-03-29 |
로슈 글리카트 아게 |
이중특이적 항원 결합 분자
|
|
LT2748201T
(lt)
|
2011-08-23 |
2018-02-26 |
Roche Glycart Ag |
Dvigubai specifinė t ląsteles aktyvinantį antigeną surišanti molekulė
|
|
WO2013033008A2
(en)
|
2011-08-26 |
2013-03-07 |
Merrimack Pharmaceuticals, Inc. |
Tandem fc bispecific antibodies
|
|
CN103930781A
(zh)
|
2011-09-15 |
2014-07-16 |
霍夫曼-拉罗奇有限公司 |
促进分化的方法
|
|
GB201116092D0
(en)
|
2011-09-16 |
2011-11-02 |
Bioceros B V |
Antibodies and uses thereof
|
|
AU2012312515A1
(en)
|
2011-09-19 |
2014-03-13 |
Genentech, Inc. |
Combination treatments comprising c-met antagonists and B-raf antagonists
|
|
AP2014007588A0
(en)
|
2011-09-22 |
2014-04-30 |
Amgen Inc |
CD27L antigen binding proteins
|
|
TWI583699B
(zh)
|
2011-09-23 |
2017-05-21 |
安可美德藥物股份有限公司 |
Vegf/dll4結合劑類及彼等之用途
|
|
CA2791109C
(en)
|
2011-09-26 |
2021-02-16 |
Merus B.V. |
Generation of binding molecules
|
|
US20130089562A1
(en)
|
2011-10-05 |
2013-04-11 |
Genenthech, Inc. |
Methods of treating liver conditions using notch2 antagonists
|
|
US12466897B2
(en)
|
2011-10-10 |
2025-11-11 |
Xencor, Inc. |
Heterodimeric human IgG1 polypeptides with isoelectric point modifications
|
|
US10851178B2
(en)
|
2011-10-10 |
2020-12-01 |
Xencor, Inc. |
Heterodimeric human IgG1 polypeptides with isoelectric point modifications
|
|
SI2766397T1
(sl)
|
2011-10-11 |
2018-09-28 |
F. Hoffmann-La Roche Ag |
Izboljšano sestavljanje bispecifičnih protiteles
|
|
PE20141562A1
(es)
|
2011-10-14 |
2014-11-12 |
Genentech Inc |
Anticuerpos anti-htra1 y metodos de uso
|
|
US9358250B2
(en)
|
2011-10-15 |
2016-06-07 |
Genentech, Inc. |
Methods of using SCD1 antagonists
|
|
TW201806968A
(zh)
|
2011-10-18 |
2018-03-01 |
艾利倫治療公司 |
擬肽巨環化合物
|
|
WO2013059531A1
(en)
|
2011-10-20 |
2013-04-25 |
Genentech, Inc. |
Anti-gcgr antibodies and uses thereof
|
|
WO2013059740A1
(en)
|
2011-10-21 |
2013-04-25 |
Foundation Medicine, Inc. |
Novel alk and ntrk1 fusion molecules and uses thereof
|
|
IN2014CN03887A
(pl)
|
2011-10-27 |
2015-10-16 |
Genmab As |
|
|
KR20140097205A
(ko)
|
2011-10-28 |
2014-08-06 |
제넨테크, 인크. |
흑색종을 치료하는 치료 조합물 및 방법
|
|
BR112014010257A2
(pt)
|
2011-10-31 |
2017-04-18 |
Chugai Pharmaceutical Co Ltd |
molécula de ligação ao antígeno tendo conjugação regulada entre cadeias pesadas e cadeias leves
|
|
US9574010B2
(en)
*
|
2011-11-04 |
2017-02-21 |
Zymeworks Inc. |
Stable heterodimeric antibody design with mutations in the Fc domain
|
|
SG11201402485UA
(en)
|
2011-11-21 |
2014-06-27 |
Genentech Inc |
Purification of anti-c-met antibodies
|
|
SG11201402490XA
(en)
|
2011-11-23 |
2014-06-27 |
Amgen Inc |
Methods of treatment using an antibody against interferon gamma
|
|
EP2788024A1
(en)
|
2011-12-06 |
2014-10-15 |
F.Hoffmann-La Roche Ag |
Antibody formulation
|
|
WO2013096221A1
(en)
|
2011-12-21 |
2013-06-27 |
Amgen Inc. |
Variant fc-polypeptides with enhanced binding to the neonatal fc receptor
|
|
EP2794662A1
(en)
|
2011-12-22 |
2014-10-29 |
F.Hoffmann-La Roche Ag |
Full length antibody display system for eukaryotic cells and its use
|
|
SG10201700169PA
(en)
|
2011-12-22 |
2017-02-27 |
Hoffmann La Roche |
Expression vector element combinations, novel production cell generation methods and their use for the recombinant production of polypeptides
|
|
CN107881196A
(zh)
|
2011-12-22 |
2018-04-06 |
弗·哈夫曼-拉罗切有限公司 |
表达载体组织、新的生产用细胞产生方法及其在重组产生多肽中的用途
|
|
AR089434A1
(es)
|
2011-12-23 |
2014-08-20 |
Genentech Inc |
Procedimiento para preparar formulaciones con alta concentracion de proteinas
|
|
AR089529A1
(es)
|
2011-12-30 |
2014-08-27 |
Abbvie Inc |
Proteinas de union especificas duales dirigidas contra il-13 y/o il-17
|
|
CN102558355B
(zh)
*
|
2011-12-31 |
2015-02-25 |
苏州康宁杰瑞生物科技有限公司 |
基于电荷网络的异二聚体fc改造方法及异二聚体蛋白的制备方法
|
|
RU2014133547A
(ru)
|
2012-01-18 |
2016-03-10 |
Дженентек, Инк. |
Способы применения модуляторов fgf19
|
|
SG10201601747XA
(en)
|
2012-01-18 |
2016-04-28 |
Genentech Inc |
Anti-LRP5 Antibodies And Methods Of Use
|
|
KR20140125803A
(ko)
|
2012-01-26 |
2014-10-29 |
암젠 인크 |
성장 분화 인자 15(gdf-15) 폴리펩타이드들
|
|
WO2013113615A1
(en)
|
2012-02-03 |
2013-08-08 |
F. Hoffmann-La Roche Ag |
Bispecific antibody molecules with antigen-transfected t-cells and their use in medicine
|
|
EP4624490A3
(en)
|
2012-02-09 |
2025-11-05 |
Chugai Seiyaku Kabushiki Kaisha |
Modified fc region of antibody
|
|
BR112014019741A2
(pt)
|
2012-02-11 |
2020-12-22 |
Genentech, Inc |
Usos de um antagonista da via wnt, uso de uma terapia anticâncer, método de identificação de um indivíduo com câncer, métodos para prever, método de inibição da proliferação de uma célula de câncer, uso de um antagonista da translocação de r-spondina e antagonista da translocação de r-spondina isolado
|
|
HK1205454A1
(en)
|
2012-02-15 |
2015-12-18 |
Aileron Therapeutics, Inc. |
Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles
|
|
KR102069397B1
(ko)
|
2012-02-15 |
2020-01-22 |
에프. 호프만-라 로슈 아게 |
Fc-수용체 기재 친화성 크로마토그래피
|
|
KR102112373B1
(ko)
|
2012-02-15 |
2020-05-18 |
에일러론 테라퓨틱스 인코포레이티드 |
펩티드모방체 마크로사이클
|
|
CA2865158C
(en)
|
2012-02-24 |
2022-11-01 |
Chugai Seiyaku Kabushiki Kaisha |
Antigen-binding molecule for promoting disappearance of antigen via fc.gamma.riib
|
|
WO2013148315A1
(en)
|
2012-03-27 |
2013-10-03 |
Genentech, Inc. |
Diagnosis and treatments relating to her3 inhibitors
|
|
JP6254146B2
(ja)
|
2012-03-27 |
2017-12-27 |
エヌジーエム バイオファーマシューティカルス,インコーポレーテッド |
代謝障害を治療するための組成物および方法
|
|
AR090549A1
(es)
|
2012-03-30 |
2014-11-19 |
Genentech Inc |
Anticuerpos anti-lgr5 e inmunoconjugados
|
|
KR101674784B1
(ko)
|
2012-04-05 |
2016-11-09 |
에프. 호프만-라 로슈 아게 |
인간 tweak 및 인간 il17에 대한 이중특이적 항체 및 이의 용도
|
|
WO2013157953A1
(en)
|
2012-04-20 |
2013-10-24 |
Merus B.V. |
Methods and means for the production of ig-like molecules
|
|
US9212227B2
(en)
|
2012-04-30 |
2015-12-15 |
Janssen Biotech, Inc. |
ST2L antibody antagonists for the treatment of ST2L-mediated inflammatory pulmonary conditions
|
|
KR20150006000A
(ko)
|
2012-05-01 |
2015-01-15 |
제넨테크, 인크. |
항-pmel17 항체 및 면역접합체
|
|
EP2847224A4
(en)
*
|
2012-05-10 |
2016-04-27 |
Zymeworks Inc |
SINGLE ARM MONOVALENT ANTIBODY CONSTRUCTS AND USES THEREOF
|
|
JP6351572B2
(ja)
*
|
2012-05-10 |
2018-07-04 |
ザイムワークス,インコーポレイテッド |
Fcドメインに突然変異を有する免疫グロブリン重鎖のヘテロ多量体構築物
|
|
WO2013170191A1
(en)
|
2012-05-11 |
2013-11-14 |
Genentech, Inc. |
Methods of using antagonists of nad biosynthesis from nicotinamide
|
|
AR091069A1
(es)
|
2012-05-18 |
2014-12-30 |
Amgen Inc |
Proteinas de union a antigeno dirigidas contra el receptor st2
|
|
WO2013177062A2
(en)
|
2012-05-21 |
2013-11-28 |
Genentech, Inc. |
Methods for improving safety of blood-brain barrier transport
|
|
EP2852840B1
(en)
|
2012-05-23 |
2019-10-09 |
F.Hoffmann-La Roche Ag |
Selection method for therapeutic agents
|
|
EP4310191A3
(en)
|
2012-06-14 |
2024-05-15 |
Chugai Seiyaku Kabushiki Kaisha |
Antigen-binding molecule containing modified fc region
|
|
AR091462A1
(es)
|
2012-06-15 |
2015-02-04 |
Genentech Inc |
Anticuerpos anti-pcsk9, formulaciones, dosificacion y metodos de uso
|
|
US9890215B2
(en)
|
2012-06-22 |
2018-02-13 |
King's College London |
Vista modulators for diagnosis and treatment of cancer
|
|
CN104619722B
(zh)
|
2012-06-22 |
2022-10-04 |
达特茅斯大学理事会 |
新型vista-ig构建体和vista-ig用于治疗自身免疫性、过敏性和炎性疾病的用途
|
|
WO2014004586A1
(en)
|
2012-06-25 |
2014-01-03 |
Zymeworks Inc. |
Process and methods for efficient manufacturing of highly pure asymmetric antibodies in mammalian cells
|
|
EP2869837B1
(en)
|
2012-07-04 |
2016-09-14 |
F. Hoffmann-La Roche AG |
Anti-theophylline antibodies and methods of use
|
|
SG11201407420RA
(en)
|
2012-07-04 |
2015-02-27 |
Hoffmann La Roche |
Covalently linked antigen-antibody conjugates
|
|
MX354303B
(es)
|
2012-07-04 |
2018-02-23 |
Hoffmann La Roche |
Anticuerpos de anti-biotina y metodos de uso.
|
|
PL2870247T3
(pl)
|
2012-07-05 |
2019-10-31 |
Hoffmann La Roche |
Układ ekspresji i wydzielania
|
|
WO2014006217A1
(en)
|
2012-07-06 |
2014-01-09 |
Genmab B.V. |
Dimeric protein with triple mutations
|
|
EP3632462A1
(en)
|
2012-07-06 |
2020-04-08 |
Genmab B.V. |
Dimeric protein with triple mutations
|
|
AU2013288932A1
(en)
|
2012-07-09 |
2014-12-11 |
Genentech, Inc. |
Immunoconjugates comprising anti - CD79b antibodies
|
|
KR20150027829A
(ko)
|
2012-07-09 |
2015-03-12 |
제넨테크, 인크. |
항-cd22 항체를 포함하는 면역접합체
|
|
BR112015000437A2
(pt)
|
2012-07-09 |
2017-06-27 |
Genentech Inc |
imunoconjugados, formulação farmacêutica, métodos de tratamento e de inbir a proliferação de uma célula
|
|
CA2874904A1
(en)
|
2012-07-09 |
2014-01-16 |
Genentech, Inc. |
Immunoconjugates comprising anti-cd22 antibodies
|
|
KR20150029714A
(ko)
|
2012-07-13 |
2015-03-18 |
더 트러스티스 오브 더 유니버시티 오브 펜실바니아 |
이중특이적 항체의 공-도입에 의한 car 세포의 활성 증강
|
|
SI3495387T1
(sl)
|
2012-07-13 |
2021-12-31 |
Roche Glycart Ag |
Bispecifična protitelesa proti VEGF/proti ANG-2 in njihova uporaba pri zdravljenju bolezni očesnih žil
|
|
BR112015000798A2
(pt)
*
|
2012-07-13 |
2017-06-27 |
Zymeworks Inc |
heterodímeros assimétricos biespecíficos compreendendo construtos anti-cd3
|
|
IN2015DN01115A
(pl)
|
2012-07-13 |
2015-06-26 |
Zymeworks Inc |
|
|
US20150166630A1
(en)
|
2012-07-19 |
2015-06-18 |
Amgen Inc. |
Btnl3 proteins, nucleic acids, and antibodies and uses thereof
|
|
CN102851338A
(zh)
*
|
2012-07-25 |
2013-01-02 |
苏州康宁杰瑞生物科技有限公司 |
利用电荷排斥作用制备同二聚体蛋白混合物的方法
|
|
PL3434695T3
(pl)
|
2012-08-07 |
2021-05-17 |
Roche Glycart Ag |
Ulepszona immunoterapia
|
|
WO2014023709A1
(en)
|
2012-08-09 |
2014-02-13 |
Roche Glycart Ag |
Asgpr antibodies and uses thereof
|
|
JP6774164B2
(ja)
|
2012-08-24 |
2020-10-21 |
中外製薬株式会社 |
マウスFcγRII特異的Fc抗体
|
|
TWI855488B
(zh)
|
2012-08-24 |
2024-09-11 |
日商中外製藥股份有限公司 |
FcγRIIb特異性Fc區域變異體
|
|
CA2884704C
(en)
|
2012-09-07 |
2023-04-04 |
Randolph J. Noelle |
Vista modulators for diagnosis and treatment of cancer
|
|
US20150239991A1
(en)
|
2012-09-25 |
2015-08-27 |
Glenmark Pharmaceuticals S.A. |
Purification of hetero-dimeric immunoglobulins
|
|
BR112015006824A2
(pt)
|
2012-09-27 |
2017-07-04 |
Merus B V |
anticorpo igg biespecífico, método para produzir um anticorpo igg biespecífico, anticorpo, composição farmacêutica e uso de um anticorpo igg biespecífico
|
|
EP2904093B1
(en)
|
2012-10-03 |
2019-04-10 |
Zymeworks Inc. |
Methods of quantitating heavy and light chain polypeptide pairs
|
|
WO2014054804A1
(ja)
|
2012-10-05 |
2014-04-10 |
協和発酵キリン株式会社 |
ヘテロダイマータンパク質組成物
|
|
MX2015003616A
(es)
|
2012-10-08 |
2015-06-05 |
Roche Glycart Ag |
Anticuerpos sin fc que comprenden dos fragmentos fab y metodos de uso.
|
|
CA2889638A1
(en)
|
2012-10-31 |
2014-05-08 |
Oncomed Pharmaceuticals, Inc. |
Methods and monitoring of treatment with a dll4 antagonist
|
|
WO2014071241A1
(en)
|
2012-11-01 |
2014-05-08 |
Aileron Therapeutics, Inc. |
Disubstituted amino acids and methods of preparation and use thereof
|
|
PE20151179A1
(es)
|
2012-11-01 |
2015-09-12 |
Abbvie Inc |
Inmunoglobulinas de dominio variable dual anti-vegf/dll4 y usos de las mismas
|
|
EP4223770A3
(en)
|
2012-11-05 |
2023-10-18 |
Foundation Medicine, Inc. |
Novel fusion molecules and uses thereof
|
|
JP6506024B2
(ja)
|
2012-11-05 |
2019-04-24 |
全薬工業株式会社 |
抗体又は抗体組成物の製造方法
|
|
EP2914621B1
(en)
|
2012-11-05 |
2023-06-07 |
Foundation Medicine, Inc. |
Novel ntrk1 fusion molecules and uses thereof
|
|
CN104755500B
(zh)
|
2012-11-08 |
2020-10-02 |
霍夫曼-拉罗奇有限公司 |
结合HER3 β-发夹的HER3抗原结合蛋白
|
|
BR112015010817A8
(pt)
|
2012-11-13 |
2018-01-23 |
Genentech Inc |
anticorpos anti-hemaglutinina isolado, método de tratamento, inibição ou prevenção de infecções, composição, composição farmacêutica, ácido nucleico isolado, célula hospedeira, método de produção de anticorpos e uso do anticorpo anti-hemaglutinina
|
|
UY35148A
(es)
|
2012-11-21 |
2014-05-30 |
Amgen Inc |
Immunoglobulinas heterodiméricas
|
|
US9562110B2
(en)
*
|
2012-11-21 |
2017-02-07 |
Wuhan Yzy Biopharma Co., Ltd. |
Bispecific antibody
|
|
EA032681B1
(ru)
*
|
2012-11-27 |
2019-07-31 |
Аджоу Юниверсити Индастри-Академик Кооперейшн Фаундейшн |
ГЕТЕРОДИМЕР Fc ИММУНОГЛОБУЛИНА, СОДЕРЖАЩИЙ ВАРИАНТ ДОМЕНА CH3 ДЛЯ ОБРАЗОВАНИЯ АНТИТЕЛА ИЛИ ГИБРИДНОГО БЕЛКА С ГЕТЕРОМЕРНЫМ Fc С ВЫСОКОЙ ЭФФЕКТИВНОСТЬЮ, СПОСОБ ДЛЯ ЕГО ПОЛУЧЕНИЯ И ИСПОЛЬЗОВАНИЯ
|
|
US9914785B2
(en)
|
2012-11-28 |
2018-03-13 |
Zymeworks Inc. |
Engineered immunoglobulin heavy chain-light chain pairs and uses thereof
|
|
MX385344B
(es)
|
2012-11-28 |
2025-03-18 |
Zymeworks Bc Inc |
Pares de cadena pesada-cadena ligera de inmunoglobulina modificados genéticamente y usos de estos.
|
|
CN105102618B
(zh)
|
2012-12-27 |
2018-04-17 |
中外制药株式会社 |
异源二聚化多肽
|
|
MX387324B
(es)
|
2013-01-10 |
2025-03-18 |
Genmab Bv |
Variantes de regiones fc de igg1 de humano y usos de las mismas.
|
|
US11053316B2
(en)
|
2013-01-14 |
2021-07-06 |
Xencor, Inc. |
Optimized antibody variable regions
|
|
US9605084B2
(en)
|
2013-03-15 |
2017-03-28 |
Xencor, Inc. |
Heterodimeric proteins
|
|
US10131710B2
(en)
|
2013-01-14 |
2018-11-20 |
Xencor, Inc. |
Optimized antibody variable regions
|
|
US10487155B2
(en)
|
2013-01-14 |
2019-11-26 |
Xencor, Inc. |
Heterodimeric proteins
|
|
KR102391731B1
(ko)
*
|
2013-01-14 |
2022-04-27 |
젠코어 인코포레이티드 |
신규한 이형이량체 단백질
|
|
US9701759B2
(en)
|
2013-01-14 |
2017-07-11 |
Xencor, Inc. |
Heterodimeric proteins
|
|
US10968276B2
(en)
|
2013-03-12 |
2021-04-06 |
Xencor, Inc. |
Optimized anti-CD3 variable regions
|
|
WO2014113510A1
(en)
|
2013-01-15 |
2014-07-24 |
Xencor, Inc. |
Rapid clearance of antigen complexes using novel antibodies
|
|
CA2898326C
(en)
|
2013-01-18 |
2022-05-17 |
Foundation Medicine, Inc. |
Methods of treating cholangiocarcinoma
|
|
WO2014116749A1
(en)
|
2013-01-23 |
2014-07-31 |
Genentech, Inc. |
Anti-hcv antibodies and methods of using thereof
|
|
EP2948478B1
(en)
|
2013-01-25 |
2019-04-03 |
Amgen Inc. |
Antibodies targeting cdh19 for melanoma
|
|
US9161966B2
(en)
|
2013-01-30 |
2015-10-20 |
Ngm Biopharmaceuticals, Inc. |
GDF15 mutein polypeptides
|
|
CA2899170C
(en)
|
2013-01-30 |
2022-08-02 |
Ngm Biopharmaceuticals, Inc. |
Compositions and methods of use in treating metabolic disorders
|
|
HK1218930A1
(zh)
|
2013-02-08 |
2017-03-17 |
Abbvie Stemcentrx Llc |
新型多特异性结构
|
|
EP2956468B1
(en)
|
2013-02-12 |
2020-06-10 |
Bristol-Myers Squibb Company |
Tangential flow filtration based protein refolding methods
|
|
US10065987B2
(en)
|
2013-02-12 |
2018-09-04 |
Bristol-Myers Squibb Company |
High pH protein refolding methods
|
|
JP6225197B2
(ja)
*
|
2013-02-15 |
2017-11-01 |
アール−ファーム・ジョイント・ストック・カンパニーR−Pharm,Jsc |
IL−1β阻害剤組成物およびその使用
|
|
WO2014128235A1
(en)
|
2013-02-22 |
2014-08-28 |
F. Hoffmann-La Roche Ag |
Methods of treating cancer and preventing drug resistance
|
|
CN104936985A
(zh)
|
2013-02-26 |
2015-09-23 |
罗切格利卡特公司 |
双特异性t细胞活化性抗原结合分子
|
|
MX2015010789A
(es)
|
2013-02-26 |
2015-11-26 |
Roche Glycart Ag |
Anticuerpos anti-pcsm.
|
|
CN110437337B
(zh)
|
2013-02-26 |
2024-07-30 |
罗切格利卡特公司 |
双特异性t细胞活化性抗原结合分子
|
|
WO2014131694A1
(en)
|
2013-02-26 |
2014-09-04 |
Roche Glycart Ag |
Bispecific t cell activating antigen binding molecules
|
|
SG11201506451UA
(en)
|
2013-03-06 |
2015-09-29 |
Merrimack Pharmaceuticals Inc |
Anti-c-met tandem fc bispecific antibodies
|
|
JP2016510751A
(ja)
|
2013-03-06 |
2016-04-11 |
ジェネンテック, インコーポレイテッド |
抗がん剤耐性を治療及び予防する方法
|
|
US9458246B2
(en)
|
2013-03-13 |
2016-10-04 |
Amgen Inc. |
Proteins specific for BAFF and B7RP1
|
|
PH12022550138A1
(en)
|
2013-03-13 |
2023-03-06 |
Amgen Inc |
Proteins specific for baff and b7rp1 and uses thereof
|
|
KR101813708B1
(ko)
*
|
2013-03-13 |
2017-12-29 |
(주) 아이벤트러스 |
소수성 상호작용 부위내에 전기적 상호작용이 도입된 단백질 및 이의 제조방법
|
|
WO2014152358A2
(en)
|
2013-03-14 |
2014-09-25 |
Genentech, Inc. |
Combinations of a mek inhibitor compound with an her3/egfr inhibitor compound and methods of use
|
|
US9562099B2
(en)
|
2013-03-14 |
2017-02-07 |
Genentech, Inc. |
Anti-B7-H4 antibodies and immunoconjugates
|
|
US9580486B2
(en)
*
|
2013-03-14 |
2017-02-28 |
Amgen Inc. |
Interleukin-2 muteins for the expansion of T-regulatory cells
|
|
EP2968565A2
(en)
|
2013-03-14 |
2016-01-20 |
Genentech, Inc. |
Methods of treating cancer and preventing cancer drug resistance
|
|
MX2015010777A
(es)
|
2013-03-14 |
2016-04-25 |
Genentech Inc |
Anticuerpos e inmunoconjugados anti-b7-h4.
|
|
WO2014151910A1
(en)
|
2013-03-15 |
2014-09-25 |
Amgen Inc. |
Heterodimeric bispecific antibodies
|
|
EP3587448B1
(en)
*
|
2013-03-15 |
2021-05-19 |
Xencor, Inc. |
Heterodimeric proteins
|
|
KR20150131269A
(ko)
|
2013-03-15 |
2015-11-24 |
제넨테크, 인크. |
Pd-1 및 pd-l1 관련 상태를 치료하기 위한 바이오마커 및 방법
|
|
US10106624B2
(en)
|
2013-03-15 |
2018-10-23 |
Xencor, Inc. |
Heterodimeric proteins
|
|
HK1214533A1
(zh)
|
2013-03-15 |
2016-07-29 |
基因泰克公司 |
治疗癌症和预防癌症耐药性的方法
|
|
US10858417B2
(en)
|
2013-03-15 |
2020-12-08 |
Xencor, Inc. |
Heterodimeric proteins
|
|
EP3421495A3
(en)
|
2013-03-15 |
2019-05-15 |
Xencor, Inc. |
Modulation of t cells with bispecific antibodies and fc fusions
|
|
BR112015021521A2
(pt)
|
2013-03-15 |
2017-10-10 |
Genentech Inc |
anticorpos anti-crth2 e métodos para seu uso
|
|
US20140302037A1
(en)
*
|
2013-03-15 |
2014-10-09 |
Amgen Inc. |
BISPECIFIC-Fc MOLECULES
|
|
AU2014227732A1
(en)
|
2013-03-15 |
2015-09-17 |
Abbvie Inc. |
Dual specific binding proteins directed against IL-1 beta and IL-17
|
|
MX2015011444A
(es)
|
2013-03-15 |
2015-12-16 |
Genentech Inc |
Composiciones y metodos para el diagnostico y tratamiento del cancer hepatico.
|
|
US10519242B2
(en)
|
2013-03-15 |
2019-12-31 |
Xencor, Inc. |
Targeting regulatory T cells with heterodimeric proteins
|
|
CN105358575B
(zh)
|
2013-03-15 |
2020-09-22 |
詹森生物科技公司 |
干扰素α和ω抗体拮抗剂
|
|
MX374811B
(es)
|
2013-03-15 |
2025-03-06 |
Ac Immune Sa |
Anticuerpos anti-tau y métodos de uso.
|
|
RS57840B1
(sr)
|
2013-03-18 |
2018-12-31 |
Biocerox Prod Bv |
Humanizovana anti-cd 134 (ox40) antitela i njihove upotrebe
|
|
SG11201508170TA
(en)
|
2013-04-02 |
2015-11-27 |
Chugai Pharmaceutical Co Ltd |
Fc REGION VARIANT
|
|
UA118028C2
(uk)
|
2013-04-03 |
2018-11-12 |
Рош Глікарт Аг |
Біспецифічне антитіло, специфічне щодо fap і dr5, антитіло, специфічне щодо dr5, і спосіб їх застосування
|
|
CA2904805A1
(en)
*
|
2013-04-29 |
2014-11-06 |
F. Hoffmann-La Roche Ag |
Fc-receptor binding modified asymmetric antibodies and methods of use
|
|
CA2904806C
(en)
|
2013-04-29 |
2021-11-23 |
F. Hoffmann-La Roche Ag |
Human fcrn-binding modified antibodies and methods of use
|
|
TW201920285A
(zh)
|
2013-04-29 |
2019-06-01 |
瑞士商赫孚孟拉羅股份公司 |
遏止FcRn結合之抗IGF-1R抗體及其治療血管性眼疾之用途
|
|
US10239951B2
(en)
|
2013-05-08 |
2019-03-26 |
Zymeworks Inc. |
Bispecific HER2 and HER3 antigen binding constructs
|
|
SG11201509566RA
(en)
|
2013-05-20 |
2015-12-30 |
Genentech Inc |
Anti-transferrin receptor antibodies and methods of use
|
|
HUE056580T2
(hu)
|
2013-05-30 |
2022-02-28 |
Kiniksa Pharmaceuticals Ltd |
Onkosztatin-M-receptor antigénjét kötõ fehérjék
|
|
KR102813816B1
(ko)
|
2013-07-05 |
2025-05-29 |
젠맵 에이/에스 |
인간화 또는 키메라 cd3 항체
|
|
LT3027642T
(lt)
|
2013-07-31 |
2020-10-12 |
Amgen Inc. |
Augimo ir diferenciacijos faktoriaus 15(gdf-15) konstruktai
|
|
CN105722855B
(zh)
*
|
2013-09-05 |
2021-04-23 |
Igm生物科学股份有限公司 |
恒定链经修饰的双特异性五价和六价Ig-M抗体
|
|
BR112016004450A2
(pt)
|
2013-09-17 |
2017-10-17 |
Genentech Inc |
métodos para tratar uma doença, para aumentar a eficácia de um tratamento, para adiar e/ou prevenir desenvolvimento da reincidência e/ou resistência de uma doença, para aumentar a sensibilidade a um inibidor, para estender o período de sensibilidade a um inibidor e para estender a duração de resposta a um inibidor
|
|
WO2015048272A1
(en)
|
2013-09-25 |
2015-04-02 |
Amgen Inc. |
V-c-fc-v-c antibody
|
|
CA2925256C
(en)
*
|
2013-09-27 |
2023-08-15 |
Chugai Seiyaku Kabushiki Kaisha |
Method for producing polypeptide heteromultimer
|
|
WO2015054670A1
(en)
|
2013-10-11 |
2015-04-16 |
Genentech, Inc. |
Nsp4 inhibitors and methods of use
|
|
BR112016006929A2
(pt)
|
2013-10-11 |
2017-09-19 |
Hoffmann La Roche |
Anticorpo, ácido nucleico, vetor de expressão, célula hospedeira, métodos de preparação de anticorpo, de tratamento de pacientes e de geração de um anticorpo, composição farmacêutica e uso do anticorpo
|
|
US20150147333A1
(en)
|
2013-10-18 |
2015-05-28 |
Genentech, Inc. |
Anti-rspo antibodies and methods of use
|
|
JP6715767B2
(ja)
|
2013-10-23 |
2020-07-01 |
ジェネンテック, インコーポレイテッド |
好酸球性疾患の診断及び治療方法
|
|
SMT202100473T1
(it)
|
2013-11-06 |
2021-09-14 |
Janssen Biotech Inc |
Anticorpi anti-ccl17
|
|
EP3068892A4
(en)
|
2013-11-13 |
2017-05-31 |
Zymeworks Inc. |
Monovalent antigen binding constructs targeting egfr and/or her2 and uses thereof
|
|
LT3071597T
(lt)
|
2013-11-21 |
2020-10-12 |
F. Hoffmann-La Roche Ag |
Antikūnai prieš alfa-sunukleiną ir jų naudojimo būdai
|
|
LT3074424T
(lt)
|
2013-11-27 |
2025-05-26 |
Zymeworks Bc Inc. |
Bispecifiniai antigeną surišantys konstruktai, nukreipti į her2
|
|
AR098743A1
(es)
|
2013-12-13 |
2016-06-08 |
Genentech Inc |
Anticuerpos e inmunoconjugados anti-cd33
|
|
CR20160270A
(es)
|
2013-12-20 |
2016-09-05 |
Hoffmann La Roche |
ANTICUERPOS ANTI-TAU (pS422) HUMANIZADOS Y MÉTODOS DE UTILIZACIÓN
|
|
TWI728373B
(zh)
|
2013-12-23 |
2021-05-21 |
美商建南德克公司 |
抗體及使用方法
|
|
US11014987B2
(en)
|
2013-12-24 |
2021-05-25 |
Janssen Pharmaceutics Nv |
Anti-vista antibodies and fragments, uses thereof, and methods of identifying same
|
|
US10273301B2
(en)
|
2013-12-24 |
2019-04-30 |
Janssen Pharmaceutica Nv |
Anti-vista antibodies and fragments
|
|
BR112016014945A2
(pt)
|
2014-01-03 |
2018-01-23 |
F. Hoffmann-La Roche Ag |
conjugado, formulação farmacêutica e uso
|
|
EP3089758B1
(en)
|
2014-01-03 |
2021-01-27 |
F.Hoffmann-La Roche Ag |
Covalently linked helicar-anti-helicar antibody conjugates and uses thereof
|
|
WO2015101586A1
(en)
|
2014-01-03 |
2015-07-09 |
F. Hoffmann-La Roche Ag |
Bispecific anti-hapten/anti-blood brain barrier receptor antibodies, complexes thereof and their use as blood brain barrier shuttles
|
|
PL3092251T3
(pl)
|
2014-01-06 |
2021-08-02 |
F. Hoffmann-La Roche Ag |
Jednowartościowe moduły transportera wahadłowego przez barierę krew-mózg
|
|
EP3093295B1
(en)
|
2014-01-08 |
2020-05-27 |
Shanghai Hengrui Pharmaceutical Co., Ltd. |
Il-15 heterogeneous dimer protein and uses thereof
|
|
CN110903398B
(zh)
|
2014-01-15 |
2023-08-15 |
豪夫迈·罗氏有限公司 |
具有修饰的FCRN和保持的蛋白A结合性质的Fc区变体
|
|
CN110981957B
(zh)
|
2014-01-15 |
2024-12-24 |
豪夫迈·罗氏有限公司 |
具有改善的蛋白A结合作用的Fc区变体
|
|
UA122479C2
(uk)
|
2014-01-24 |
2020-11-25 |
Дана-Фарбер Кенсер Інстітьют, Інк. |
Виділена молекула антитіла, яка зв’язується з людським білком програмованої смерті-1 (pd-1)
|
|
WO2015112909A1
(en)
|
2014-01-24 |
2015-07-30 |
Genentech, Inc. |
Methods of using anti-steap1 antibodies and immunoconjugates
|
|
PL3099717T3
(pl)
|
2014-01-31 |
2019-10-31 |
Novartis Ag |
Cząsteczki przeciwciała dla TIM-3 i ich zastosowanie
|
|
TW202239429A
(zh)
|
2014-02-08 |
2022-10-16 |
美商建南德克公司 |
治療阿茲海默症之方法
|
|
NZ723884A
(en)
|
2014-02-08 |
2023-02-24 |
Genentech Inc |
Methods of treating alzheimer’s disease
|
|
SI3105253T1
(sl)
|
2014-02-12 |
2018-10-30 |
F. Hoffmann-La Roche Ag |
Protitelesa anti-Jagged1 in načini njihove uporabe
|
|
JP2017507939A
(ja)
|
2014-02-21 |
2017-03-23 |
ジェネンテック, インコーポレイテッド |
抗il−13/il−17二重特異性抗体及びその使用
|
|
CA2941030C
(en)
|
2014-02-28 |
2025-05-13 |
Merus N.V. |
ANTIBODIES THAT BIND TO EGFR AND ERBB3
|
|
US9732154B2
(en)
|
2014-02-28 |
2017-08-15 |
Janssen Biotech, Inc. |
Anti-CD38 antibodies for treatment of acute lymphoblastic leukemia
|
|
DK3805268T3
(da)
|
2014-02-28 |
2025-01-20 |
Merus Nv |
Antistof, der binder erbb-2 og erbb-3
|
|
SG11201607519VA
(en)
|
2014-03-14 |
2016-10-28 |
Genentech Inc |
Methods and compositions for secretion of heterologous polypeptides
|
|
EA201691765A1
(ru)
|
2014-03-14 |
2016-12-30 |
Новартис Аг |
Молекулы антител против lag-3 и их применения
|
|
CN122399016A
(zh)
|
2014-03-15 |
2026-07-17 |
诺华股份有限公司 |
使用嵌合抗原受体治疗癌症
|
|
US20170107294A1
(en)
|
2014-03-21 |
2017-04-20 |
Nordlandssykehuset Hf |
Anti-cd14 antibodies and uses thereof
|
|
AU2015230938C1
(en)
|
2014-03-21 |
2021-10-14 |
Regeneron Pharmaceuticals, Inc. |
Non-human animals that make single domain binding proteins
|
|
EP3122900A1
(en)
|
2014-03-24 |
2017-02-01 |
F. Hoffmann-La Roche AG |
Cancer treatment with c-met antagonists and correlation of the latter with hgf expression
|
|
US12180264B2
(en)
|
2014-03-24 |
2024-12-31 |
R-Pharm Overseas, Inc. |
IL1-R1 derived inhibitor of IL-1β and use thereof
|
|
PL3122781T3
(pl)
|
2014-03-28 |
2020-06-15 |
Xencor, Inc. |
Dwuswoiste przeciwciała, które wiążą się z CD38 i CD3
|
|
KR20160146747A
(ko)
|
2014-03-31 |
2016-12-21 |
제넨테크, 인크. |
항혈관신생제 및 ox40 결합 효능제를 포함하는 조합 요법
|
|
SG11201607969XA
(en)
|
2014-03-31 |
2016-10-28 |
Genentech Inc |
Anti-ox40 antibodies and methods of use
|
|
EP4050026A1
(en)
|
2014-04-01 |
2022-08-31 |
Adimab, LLC |
Method of obtaining or identifying one or more common light chains for use in preparing a multispecific antibody
|
|
UA117289C2
(uk)
*
|
2014-04-02 |
2018-07-10 |
Ф. Хоффманн-Ля Рош Аг |
Мультиспецифічне антитіло
|
|
SG10202107077QA
(en)
|
2014-04-02 |
2021-07-29 |
Hoffmann La Roche |
Method for detecting multispecific antibody light chain mispairing
|
|
MX380176B
(es)
|
2014-04-07 |
2025-03-12 |
Chugai Pharmaceutical Co Ltd |
Molecula ligada a antigeno inmunoactivada.
|
|
WO2015160940A1
(en)
*
|
2014-04-15 |
2015-10-22 |
President And Fellows Of Harvard College |
Bi-specific agents
|
|
WO2015164615A1
(en)
|
2014-04-24 |
2015-10-29 |
University Of Oslo |
Anti-gluten antibodies and uses thereof
|
|
SG10201913507SA
(en)
*
|
2014-05-02 |
2020-02-27 |
Momenta Pharmaceuticals Inc |
Compositions and methods related to engineered fc constructs
|
|
PL3140392T3
(pl)
|
2014-05-06 |
2023-11-27 |
F. Hoffmann-La Roche Ag |
Produkcja białek heteromultimerycznych z wykorzystaniem komórek ssaków
|
|
KR20170017916A
(ko)
|
2014-05-13 |
2017-02-15 |
추가이 세이야쿠 가부시키가이샤 |
면역 억제 기능을 갖는 세포에 대한 t 세포 리다이렉트 항원 결합 분자
|
|
ES2913205T3
(es)
|
2014-05-13 |
2022-06-01 |
Bioatla Inc |
Proteínas biológicas activas condicionalmente
|
|
WO2015173756A2
(en)
|
2014-05-16 |
2015-11-19 |
Pfizer Inc. |
Bispecific antibodies
|
|
JP2017522861A
(ja)
|
2014-05-22 |
2017-08-17 |
ジェネンテック, インコーポレイテッド |
抗gpc3抗体及びイムノコンジュゲート
|
|
KR20170005016A
(ko)
|
2014-05-23 |
2017-01-11 |
제넨테크, 인크. |
MiT 바이오마커 및 그의 사용 방법
|
|
DK3107938T3
(da)
|
2014-05-28 |
2022-07-11 |
Zymeworks Inc |
Modificerede, antigenbindende polypeptidkonstrukter og anvendelser heraf
|
|
JP6568110B2
(ja)
|
2014-06-04 |
2019-08-28 |
アクセルロン ファーマ, インコーポレイテッド |
フォリスタチンポリペプチドによる障害の処置のための方法および組成物
|
|
US10010498B2
(en)
|
2014-06-04 |
2018-07-03 |
Acceleron Pharma Inc. |
Methods for treatment of amyotrophic lateral sclerosis with follistatin fusion proteins
|
|
MX2016016233A
(es)
|
2014-06-11 |
2017-03-31 |
Genentech Inc |
Anticuerpos anti-lgr5 y sus usos.
|
|
JP6997619B2
(ja)
|
2014-06-11 |
2022-01-17 |
キャシー・エイ・グリーン |
液性免疫の抑制または増進のための、vistaアゴニスト及びvistaアンタゴニストの使用
|
|
WO2015191986A1
(en)
|
2014-06-13 |
2015-12-17 |
Genentech, Inc. |
Methods of treating and preventing cancer drug resistance
|
|
TWI713453B
(zh)
|
2014-06-23 |
2020-12-21 |
美商健生生物科技公司 |
干擾素α及ω抗體拮抗劑
|
|
AR100978A1
(es)
|
2014-06-26 |
2016-11-16 |
Hoffmann La Roche |
LANZADERAS CEREBRALES DE ANTICUERPO HUMANIZADO ANTI-Tau(pS422) Y USOS DE LAS MISMAS
|
|
CN106687476B
(zh)
|
2014-06-26 |
2020-11-13 |
豪夫迈·罗氏有限公司 |
抗brdu抗体及使用方法
|
|
AU2015279321B2
(en)
|
2014-06-27 |
2021-03-04 |
Innate Pharma, S.A. |
Multispecific antigen binding proteins
|
|
JP6822849B2
(ja)
|
2014-06-27 |
2021-01-27 |
イナート・ファルマ・ソシエテ・アノニムInnate Pharma Pharma S.A. |
多重特異的NKp46結合タンパク質
|
|
TW201623329A
(zh)
|
2014-06-30 |
2016-07-01 |
亞佛瑞司股份有限公司 |
針對骨調素截斷變異體的疫苗及單株抗體暨其用途
|
|
HRP20192243T1
(hr)
|
2014-07-03 |
2020-03-06 |
F. Hoffmann - La Roche Ag |
Polipeptidni ekspresijski sustavi
|
|
JP6876601B2
(ja)
|
2014-07-10 |
2021-05-26 |
アフィリス・アクチェンゲゼルシャフトAffiris Ag |
ハンチントン病の予防および/または処置における使用のための物質および方法
|
|
CN106604933B
(zh)
|
2014-07-11 |
2021-08-10 |
文塔纳医疗系统公司 |
抗pd-l1抗体及其诊断用途
|
|
EP3166627A1
(en)
|
2014-07-11 |
2017-05-17 |
Genentech, Inc. |
Notch pathway inhibition
|
|
DK3169706T3
(da)
|
2014-07-11 |
2020-03-09 |
Genmab As |
Antistoffer, der binder axl
|
|
JP2017528433A
(ja)
|
2014-07-21 |
2017-09-28 |
ノバルティス アーゲー |
低い免疫増強用量のmTOR阻害剤とCARの組み合わせ
|
|
AU2015292744C1
(en)
|
2014-07-21 |
2021-01-21 |
Novartis Ag |
Treatment of cancer using humanized anti-BCMA chimeric antigen receptor
|
|
WO2016014553A1
(en)
|
2014-07-21 |
2016-01-28 |
Novartis Ag |
Sortase synthesized chimeric antigen receptors
|
|
US9777073B2
(en)
*
|
2014-07-21 |
2017-10-03 |
Wuhan Yzy Biopharma Co., Ltd. |
Construction and application of bispecific antibody EpCAM×CD3
|
|
JP6831777B2
(ja)
|
2014-07-21 |
2021-02-17 |
ノバルティス アーゲー |
Cd33キメラ抗原受容体を使用する癌の処置
|
|
EP3174897B1
(en)
*
|
2014-07-29 |
2020-02-12 |
F.Hoffmann-La Roche Ag |
Multispecific antibodies
|
|
JP6704358B2
(ja)
|
2014-07-30 |
2020-06-03 |
エヌジーエム バイオファーマシューティカルズ インコーポレイテッド |
代謝障害を治療するための組成物および使用方法
|
|
WO2016019300A1
(en)
|
2014-07-31 |
2016-02-04 |
Novartis Ag |
Subset-optimized chimeric antigen receptor-containing t-cells
|
|
PL3177643T3
(pl)
|
2014-08-04 |
2019-09-30 |
F.Hoffmann-La Roche Ag |
Dwuswoiste cząsteczki wiążące antygen aktywujące komórki T
|
|
EP2982692A1
(en)
|
2014-08-04 |
2016-02-10 |
EngMab AG |
Bispecific antibodies against CD3epsilon and BCMA
|
|
EP3180359A1
(en)
|
2014-08-14 |
2017-06-21 |
Novartis AG |
Treatment of cancer using gfr alpha-4 chimeric antigen receptor
|
|
EP3712171A1
(en)
|
2014-08-19 |
2020-09-23 |
Novartis AG |
Treatment of cancer using a cd123 chimeric antigen receptor
|
|
DK3186284T3
(da)
|
2014-08-28 |
2022-05-09 |
Bioatla Inc |
Betinget aktive kimæriske antigenreceptorer til modificerede t-celler
|
|
US11111288B2
(en)
|
2014-08-28 |
2021-09-07 |
Bioatla, Inc. |
Conditionally active chimeric antigen receptors for modified t-cells
|
|
US10513699B2
(en)
|
2014-09-03 |
2019-12-24 |
Bioatla, Llc |
Discovering and producing conditionally active biologic proteins in the same eukaryotic cell production hosts
|
|
WO2016040294A2
(en)
|
2014-09-09 |
2016-03-17 |
Janssen Biotech, Inc. |
Combination therapies with anti-cd38 antibodies
|
|
SI3191135T1
(sl)
|
2014-09-12 |
2021-01-29 |
Genentech, Inc. |
Anti-HER2 protitelesa in imunokonjugati
|
|
TW201625689A
(zh)
|
2014-09-12 |
2016-07-16 |
建南德克公司 |
抗-b7-h4抗體及免疫結合物
|
|
MA40579A
(fr)
|
2014-09-12 |
2016-03-17 |
Genentech Inc |
Anticorps anti-cll-1 et immunoconjugués
|
|
JP2017531620A
(ja)
|
2014-09-12 |
2017-10-26 |
ジェネンテック, インコーポレイテッド |
システイン操作抗体及びコンジュゲート
|
|
UY36302A
(es)
|
2014-09-15 |
2016-04-29 |
Amgen Inc |
Proteína de unión a antígenos, bi-específicos del receptor anti-cgrp/receptor pac1 y usos de las mismas
|
|
US10577417B2
(en)
|
2014-09-17 |
2020-03-03 |
Novartis Ag |
Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy
|
|
CA2957148A1
(en)
|
2014-09-17 |
2016-03-24 |
Genentech, Inc. |
Immunoconjugates comprising anti-her2 antibodies and pyrrolobenzodiazepines
|
|
CA2979671C
(en)
|
2014-09-23 |
2020-03-10 |
Genentech, Inc. |
Methods of using anti-cd79b immunoconjugates
|
|
JP2018503595A
(ja)
|
2014-09-24 |
2018-02-08 |
エルロン・セラピューティクス・インコーポレイテッドAileron Therapeutics,Inc. |
ペプチド模倣大環状分子およびその製剤
|
|
BR112017005598A2
(pt)
|
2014-09-24 |
2017-12-12 |
Aileron Therapeutics Inc |
macrociclos peptidomiméticos e usos dos mesmos
|
|
EP3197916A2
(en)
|
2014-09-25 |
2017-08-02 |
Amgen Inc. |
Protease-activatable bispecific proteins
|
|
MA40764A
(fr)
|
2014-09-26 |
2017-08-01 |
Chugai Pharmaceutical Co Ltd |
Agent thérapeutique induisant une cytotoxicité
|
|
EP3204415B1
(en)
|
2014-10-09 |
2020-06-17 |
EngMab Sàrl |
Bispecific antibodies against cd3epsilon and ror1
|
|
SG11201702401RA
(en)
|
2014-10-14 |
2017-04-27 |
Novartis Ag |
Antibody molecules to pd-l1 and uses thereof
|
|
JP2017536102A
(ja)
|
2014-10-16 |
2017-12-07 |
ジェネンテック, インコーポレイテッド |
抗アルファ−シヌクレイン抗体及び使用方法
|
|
PL3212225T3
(pl)
|
2014-10-31 |
2026-03-30 |
The Trustees Of The University Of Pennsylvania |
Sposoby i kompozycje zmodyfikowanych limfocytów t
|
|
CN106687128B
(zh)
|
2014-10-31 |
2022-05-10 |
Ngm生物制药有限公司 |
用于治疗代谢病症的组合物和方法
|
|
EP3212233B1
(en)
|
2014-10-31 |
2020-06-24 |
Oncomed Pharmaceuticals, Inc. |
Combination therapy for treatment of disease
|
|
CA2966507A1
(en)
|
2014-11-03 |
2016-05-12 |
Genentech, Inc. |
Methods and biomarkers for predicting efficacy and evaluation of an ox40 agonist treatment
|
|
KR20170086540A
(ko)
|
2014-11-03 |
2017-07-26 |
제넨테크, 인크. |
T 세포 면역 하위세트를 검출하기 위한 검정 및 그의 사용 방법
|
|
US11773166B2
(en)
|
2014-11-04 |
2023-10-03 |
Ichnos Sciences SA |
CD3/CD38 T cell retargeting hetero-dimeric immunoglobulins and methods of their production
|
|
PT3215528T
(pt)
|
2014-11-06 |
2019-10-11 |
Hoffmann La Roche |
Variantes da região fc com ligação modificada ao fcrn e métodos de utilização
|
|
RU2713131C1
(ru)
|
2014-11-06 |
2020-02-03 |
Ф. Хоффманн-Ля Рош Аг |
ВАРИАНТЫ Fc-ОБЛАСТИ С МОДИФИЦИРОВАННЫМИ СВОЙСТВАМИ СВЯЗЫВАНИЯ FcRn И БЕЛКА А
|
|
WO2016073157A1
(en)
|
2014-11-06 |
2016-05-12 |
Genentech, Inc. |
Anti-ang2 antibodies and methods of use thereof
|
|
JP2018500882A
(ja)
|
2014-11-10 |
2018-01-18 |
ジェネンテック, インコーポレイテッド |
腎症の動物モデルおよびそれを治療するための薬剤
|
|
JP6929771B2
(ja)
|
2014-11-10 |
2021-09-01 |
ジェネンテック, インコーポレイテッド |
抗インターロイキン−33抗体及びその使用
|
|
ES2788979T3
(es)
|
2014-11-14 |
2020-10-23 |
Hoffmann La Roche |
Moléculas de unión a antígeno que comprenden un trímero de ligando de la familia de TNF
|
|
EP3221364B1
(en)
|
2014-11-19 |
2020-12-16 |
Genentech, Inc. |
Antibodies against bace1 and use thereof for neural disease immunotherapy
|
|
JP6779876B2
(ja)
|
2014-11-19 |
2020-11-04 |
ジェネンテック, インコーポレイテッド |
抗トランスフェリン受容体抗体及びその使用方法
|
|
EP3221361B1
(en)
|
2014-11-19 |
2021-04-21 |
Genentech, Inc. |
Anti-transferrin receptor / anti-bace1 multispecific antibodies and methods of use
|
|
SG11201704056XA
(en)
|
2014-11-20 |
2017-06-29 |
Hoffmann La Roche |
Combination therapy of t cell activating bispecific antigen binding molecules cd3 abd folate receptor 1 (folr1) and pd-1 axis binding antagonists
|
|
ES2808853T3
(es)
|
2014-11-20 |
2021-03-02 |
Hoffmann La Roche |
Cadenas ligeras comunes y procedimientos de uso
|
|
RS61010B1
(sr)
|
2014-11-20 |
2020-11-30 |
Hoffmann La Roche |
Bispecifični antigen vezujući molekuli koji aktiviraju t ćelije protiv folr1 i cd3
|
|
EP3023437A1
(en)
|
2014-11-20 |
2016-05-25 |
EngMab AG |
Bispecific antibodies against CD3epsilon and BCMA
|
|
HK1245171A1
(zh)
|
2014-11-26 |
2018-08-24 |
Xencor, Inc. |
结合cd3和cd38的异二聚体抗体
|
|
US10259887B2
(en)
|
2014-11-26 |
2019-04-16 |
Xencor, Inc. |
Heterodimeric antibodies that bind CD3 and tumor antigens
|
|
JP6696982B2
(ja)
|
2014-11-26 |
2020-05-20 |
ゼンコー・インコーポレイテッドXencor、 Inc. |
Cd3および腫瘍抗原に結合するヘテロ二量体抗体
|
|
FI3223848T3
(fi)
|
2014-11-27 |
2025-02-28 |
Zymeworks Bc Inc |
Menetelmiä käyttää bispesifisiä antigeenia sitovia rakenteita, jotka kohdistuvat her2:een
|
|
US20180334490A1
(en)
|
2014-12-03 |
2018-11-22 |
Qilong H. Wu |
Methods for b cell preconditioning in car therapy
|
|
WO2016087416A1
(en)
|
2014-12-03 |
2016-06-09 |
F. Hoffmann-La Roche Ag |
Multispecific antibodies
|
|
PE20171094A1
(es)
|
2014-12-04 |
2017-08-07 |
Janssen Biotech Inc |
Anticuerpos anti-cd38 para el tratamiento de la leucemia linfoblastica aguda
|
|
MX2017007136A
(es)
|
2014-12-05 |
2017-12-04 |
Immunext Inc |
Identificacion de vsig8 como el receptor vista putativo y su uso para producir moduladores vista/vsig8.
|
|
MX386587B
(es)
|
2014-12-05 |
2025-03-19 |
Genentech Inc |
ANTICUERPOS ANTI-CD79b Y MÉTODOS DE USO.
|
|
SG11201703750XA
(en)
|
2014-12-10 |
2017-06-29 |
Genentech Inc |
Blood brain barrier receptor antibodies and methods of use
|
|
US10093733B2
(en)
|
2014-12-11 |
2018-10-09 |
Abbvie Inc. |
LRP-8 binding dual variable domain immunoglobulin proteins
|
|
BR112017011170A2
(pt)
|
2014-12-18 |
2018-02-27 |
Hoffmann La Roche |
método para determinar a citotoxicidade dependente do complemento de uma composição
|
|
EP3233907B1
(en)
*
|
2014-12-19 |
2021-03-03 |
Genmab A/S |
Rodent bispecific heterodimeric proteins
|
|
EA201791366A1
(ru)
|
2014-12-19 |
2018-02-28 |
Чугаи Сейяку Кабусики Кайся |
Антитела к c5 и способы их применения
|
|
MX2017005774A
(es)
|
2014-12-19 |
2017-07-28 |
Chugai Pharmaceutical Co Ltd |
Anticuerpos antimiostatina, polipeptidos que contienen regiones fc variantes, y metodos de uso.
|
|
US10428155B2
(en)
|
2014-12-22 |
2019-10-01 |
Xencor, Inc. |
Trispecific antibodies
|
|
CN107660214B
(zh)
|
2015-01-08 |
2022-02-08 |
根马布股份公司 |
针对cd3和cd20的双特异性抗体
|
|
CN110658340B
(zh)
*
|
2015-01-08 |
2023-10-31 |
苏州康宁杰瑞生物科技有限公司 |
具有共同轻链的双特异性抗体或抗体混合物
|
|
MA41375A
(fr)
|
2015-01-22 |
2017-11-28 |
Lilly Co Eli |
Anticorps igg bispécifiques et leurs procédés de préparation
|
|
US20180016327A1
(en)
|
2015-01-22 |
2018-01-18 |
Chugai Seiyaku Kabushiki Kaisha |
A Combination of Two or More Anti-C5 Antibodies and Methods of Use
|
|
AU2015380397B2
(en)
|
2015-01-31 |
2021-10-21 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for T cell delivery of therapeutic molecules
|
|
CN114773469B
(zh)
|
2015-02-05 |
2025-12-19 |
中外制药株式会社 |
包含离子浓度依赖性的抗原结合结构域的抗体,fc区变体,il-8-结合抗体及其应用
|
|
SG11201705988UA
(en)
|
2015-02-24 |
2017-08-30 |
Bioatla Llc |
Conditionally active biological proteins
|
|
WO2016141110A1
(en)
|
2015-03-03 |
2016-09-09 |
Schlumberger Technology Corporation |
Multi-mode acoustic tool and method
|
|
US10227411B2
(en)
|
2015-03-05 |
2019-03-12 |
Xencor, Inc. |
Modulation of T cells with bispecific antibodies and FC fusions
|
|
HRP20192217T1
(hr)
|
2015-03-06 |
2020-02-21 |
F. Hoffmann - La Roche Ag |
ULTRA-PROČIŠĆENI DsbA I DsbC TE POSTUPCI NJIHOVE IZRADE I UPORABE
|
|
EP3271723A1
(en)
|
2015-03-16 |
2018-01-24 |
F. Hoffmann-La Roche AG |
Methods of detecting and quantifying il-13 and uses in diagnosing and treating th2-associated diseases
|
|
CN107438622A
(zh)
|
2015-03-19 |
2017-12-05 |
瑞泽恩制药公司 |
选择结合抗原的轻链可变区的非人动物
|
|
WO2016146833A1
(en)
|
2015-03-19 |
2016-09-22 |
F. Hoffmann-La Roche Ag |
Biomarkers for nad(+)-diphthamide adp ribosyltransferase resistance
|
|
WO2016154058A1
(en)
|
2015-03-20 |
2016-09-29 |
Aileron Therapeutics, Inc. |
Peptidomimetic macrocycles and uses thereof
|
|
CA2980757A1
(en)
*
|
2015-03-26 |
2016-09-29 |
Acceleron Pharma Inc. |
Follistatin-related fusion proteins and uses thereof
|
|
JP7082484B2
(ja)
|
2015-04-01 |
2022-06-08 |
中外製薬株式会社 |
ポリペプチド異種多量体の製造方法
|
|
CN114456272A
(zh)
|
2015-04-03 |
2022-05-10 |
优瑞科生物技术公司 |
靶向afp肽/mhc复合体的构建体及其用途
|
|
MA41919A
(fr)
|
2015-04-06 |
2018-02-13 |
Acceleron Pharma Inc |
Hétéromultimères alk4:actriib et leurs utilisations
|
|
EP3280435B1
(en)
|
2015-04-06 |
2021-06-02 |
Acceleron Pharma Inc. |
Tgf-beta superfamily type i and type ii receptor heteromultimers and uses thereof
|
|
CN113683708A
(zh)
|
2015-04-06 |
2021-11-23 |
阿塞勒隆制药公司 |
单臂i型和ii型受体融合蛋白和其用途
|
|
MX2017012805A
(es)
|
2015-04-07 |
2018-04-11 |
Genentech Inc |
Complejo de unión a antígenos con actividad agonista y métodos de uso.
|
|
EP3991748A3
(en)
|
2015-04-07 |
2022-08-24 |
Alector LLC |
Anti-sortilin antibodies and methods of use thereof
|
|
PL3280729T3
(pl)
|
2015-04-08 |
2022-08-22 |
Novartis Ag |
Terapie cd20, terapie cd22 i terapie skojarzone komórką eksprymującą chimeryczny receptor antygenowy (car) cd19
|
|
EP3280444B1
(en)
|
2015-04-10 |
2024-05-08 |
Adimab, LLC |
Methods for purifying heterodimeric multispecific antibodies from parental homodimeric antibody species
|
|
IL304950A
(en)
|
2015-04-10 |
2023-10-01 |
Amgen Inc |
Interleukin for the expansion of myotonic control T-2 cells
|
|
CN108064245A
(zh)
|
2015-04-17 |
2018-05-22 |
埃尔萨里斯生物技术公司 |
抗Tyro3抗体及其用途
|
|
WO2016172583A1
(en)
|
2015-04-23 |
2016-10-27 |
Novartis Ag |
Treatment of cancer using chimeric antigen receptor and protein kinase a blocker
|
|
CA2980189A1
(en)
|
2015-04-24 |
2016-10-27 |
Genentech, Inc. |
Multispecific antigen-binding proteins
|
|
EP3286315B1
(en)
|
2015-04-24 |
2021-05-26 |
F. Hoffmann-La Roche AG |
Methods of identifying bacteria comprising binding polypeptides
|
|
CN116196414A
(zh)
|
2015-05-11 |
2023-06-02 |
豪夫迈·罗氏有限公司 |
治疗狼疮性肾炎的组合物和方法
|
|
DK3294770T4
(da)
|
2015-05-12 |
2024-05-21 |
Hoffmann La Roche |
Terapeutiske og diagnostiske fremgangsmåder til cancer
|
|
CR20170526A
(es)
|
2015-05-20 |
2018-04-03 |
Janssen Biotech Inc |
ANTICUERPOS ANTI-CD38 PARA EL TRATAMIENTO DE AMILOIDOSIS DE CADENA LIGERA y OTRAS ENFERMEDADES MALIGNAS HEMATOLÓGICAS POSITIVAS PARA CD38
|
|
ES2823033T3
(es)
|
2015-05-28 |
2021-05-05 |
Genentech Inc |
Ensayo basado en células para detectar homodímeros anti-CD3
|
|
EP3303632B2
(en)
|
2015-05-29 |
2023-05-10 |
F. Hoffmann-La Roche AG |
Therapeutic and diagnostic methods for cancer
|
|
EP3302563A1
(en)
|
2015-05-29 |
2018-04-11 |
H. Hoffnabb-La Roche Ag |
Humanized anti-ebola virus glycoprotein antibodies and methods of use
|
|
HK1249016A1
(zh)
|
2015-06-02 |
2018-10-26 |
豪夫迈‧罗氏有限公司 |
使用抗il-34抗体治疗神经疾病的组合物和方法
|
|
NZ775762A
(en)
|
2015-06-05 |
2025-02-28 |
Genentech Inc |
Anti-tau antibodies and methods of use
|
|
AU2016274585A1
(en)
|
2015-06-08 |
2017-12-14 |
Genentech, Inc. |
Methods of treating cancer using anti-OX40 antibodies
|
|
EP3303397A1
(en)
|
2015-06-08 |
2018-04-11 |
H. Hoffnabb-La Roche Ag |
Methods of treating cancer using anti-ox40 antibodies and pd-1 axis binding antagonists
|
|
US10017577B2
(en)
|
2015-06-15 |
2018-07-10 |
Genentech, Inc. |
Antibodies and immunoconjugates
|
|
TW201710286A
(zh)
|
2015-06-15 |
2017-03-16 |
艾伯維有限公司 |
抗vegf、pdgf及/或其受體之結合蛋白
|
|
TW201718647A
(zh)
|
2015-06-16 |
2017-06-01 |
建南德克公司 |
抗-cll-1抗體及使用方法
|
|
US10323094B2
(en)
|
2015-06-16 |
2019-06-18 |
Genentech, Inc. |
Humanized and affinity matured antibodies to FcRH5 and methods of use
|
|
EP3310811B1
(en)
|
2015-06-16 |
2021-06-16 |
Genentech, Inc. |
Anti-cd3 antibodies and methods of use
|
|
ES3043088T3
(en)
|
2015-06-17 |
2025-11-24 |
Hoffmann La Roche |
Anti-her2 antibodies and methods of use
|
|
CN107708734B
(zh)
|
2015-06-22 |
2022-01-11 |
詹森生物科技公司 |
用抗cd38抗体和生存素抑制剂联合治疗血红素恶性肿瘤
|
|
AU2016284871B2
(en)
|
2015-06-23 |
2022-09-29 |
Innate Pharma |
Multispecific NK engager proteins
|
|
JP7021955B2
(ja)
|
2015-06-24 |
2022-03-03 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
Her2及び血液脳関門受容体に特異的な三重特異性抗体及び使用方法
|
|
EP3722314A1
(en)
|
2015-06-24 |
2020-10-14 |
Janssen Pharmaceutica NV |
Anti-vista antibodies and fragments
|
|
EP3313441B1
(en)
|
2015-06-24 |
2024-02-21 |
Janssen Biotech, Inc. |
Immune modulation and treatment of solid tumors with antibodies that specifically bind cd38
|
|
ES2809728T3
(es)
|
2015-06-24 |
2021-03-05 |
Hoffmann La Roche |
Anticuerpos anti-tau(pS422) humanizados y procedimientos de uso
|
|
CN107810420B
(zh)
|
2015-06-25 |
2020-08-14 |
豪夫迈·罗氏有限公司 |
用于测定抗体或配体结合和功能的基于细胞的测定
|
|
ES2878316T3
(es)
|
2015-06-29 |
2021-11-18 |
Ventana Med Syst Inc |
Materiales y procedimientos para realizar ensayos histoquímicos de pro-epirregulina y anfirregulina humanas
|
|
WO2017004091A1
(en)
|
2015-06-29 |
2017-01-05 |
Genentech, Inc. |
Type ii anti-cd20 antibody for use in organ transplantation
|
|
US10059741B2
(en)
|
2015-07-01 |
2018-08-28 |
Aileron Therapeutics, Inc. |
Peptidomimetic macrocycles
|
|
EP3319996B1
(en)
|
2015-07-09 |
2024-01-03 |
Genmab A/S |
Bispecific and multispecific antibodies and method for isolation of such
|
|
CA2991805A1
(en)
|
2015-07-10 |
2017-01-19 |
Genmab A/S |
Axl-specific antibody-drug conjugates for cancer treatment
|
|
WO2017010874A1
(en)
|
2015-07-10 |
2017-01-19 |
Merus N.V. |
Human cd3 binding antibody
|
|
FI3322727T3
(fi)
|
2015-07-15 |
2026-03-17 |
Genmab As |
Humanisoituja tai kimeerisiä CD3-vasta-aineita
|
|
US20180340025A1
(en)
|
2015-07-29 |
2018-11-29 |
Novartis Ag |
Combination therapies comprising antibody molecules to lag-3
|
|
US20180207273A1
(en)
|
2015-07-29 |
2018-07-26 |
Novartis Ag |
Combination therapies comprising antibody molecules to tim-3
|
|
EP3328418A1
(en)
|
2015-07-29 |
2018-06-06 |
Novartis AG |
Combination therapies comprising antibody molecules to pd-1
|
|
PE20231958A1
(es)
|
2015-07-30 |
2023-12-06 |
Macrogenics Inc |
Moleculas de union a pd-1 y metodos de uso de las mismas
|
|
MY188405A
(en)
|
2015-08-05 |
2021-12-08 |
Janssen Biotech Inc |
Anti-cd154 antibodies and methods of using them
|
|
EA034582B1
(ru)
|
2015-08-07 |
2020-02-21 |
АЭлЭкс ОНКОЛОДЖИ ИНК. |
Конструкции варианта sirp-альфа и их применение
|
|
RU2740672C2
(ru)
|
2015-08-07 |
2021-01-19 |
ЭйЭлЭкс Онколоджи Инк. |
Конструкции, имеющие sirp-альфа домен или его вариант
|
|
CN105384825B
(zh)
|
2015-08-11 |
2018-06-01 |
南京传奇生物科技有限公司 |
一种基于单域抗体的双特异性嵌合抗原受体及其应用
|
|
ES2964640T3
(es)
|
2015-08-13 |
2024-04-08 |
Amgen Inc |
Filtración en profundidad cargada de proteínas de unión al antígeno
|
|
AU2016312259B2
(en)
|
2015-08-26 |
2018-12-06 |
Bison Therapeutics Inc. |
Multispecific antibody platform and related methods
|
|
WO2017040195A1
(en)
|
2015-08-28 |
2017-03-09 |
The Trustees Of The University Of Pennsylvania |
Methods and compositions for cells expressing a chimeric intracellular signaling molecule
|
|
WO2017040324A1
(en)
|
2015-08-28 |
2017-03-09 |
The Trustees Of The University Of Pennsylvania |
Methods and compositions for cells expressing a chimeric intracellular signaling molecule
|
|
AU2016319126A1
(en)
|
2015-09-10 |
2018-04-19 |
Affigen, Inc. |
Sequencing-directed selection of tumor theranostics
|
|
US10023613B2
(en)
|
2015-09-10 |
2018-07-17 |
Aileron Therapeutics, Inc. |
Peptidomimetic macrocycles as modulators of MCL-1
|
|
JP6932700B2
(ja)
|
2015-09-15 |
2021-09-08 |
アムジエン・インコーポレーテツド |
4価の二重特異性抗原結合タンパク質及び4価の四重特異性抗原結合タンパク質、ならびにそれらの使用
|
|
PE20181336A1
(es)
|
2015-09-18 |
2018-08-21 |
Chugai Pharmaceutical Co Ltd |
Anticuerpos que se unen a interleucina 8 (il-8) y sus usos
|
|
JP6904947B2
(ja)
|
2015-09-22 |
2021-07-21 |
スプリング バイオサイエンス コーポレーション |
抗ox40抗体及びその診断用途
|
|
US11339213B2
(en)
|
2015-09-23 |
2022-05-24 |
Mereo Biopharma 5, Inc. |
Methods and compositions for treatment of cancer
|
|
JP6959912B2
(ja)
|
2015-09-23 |
2021-11-05 |
ジェネンテック, インコーポレイテッド |
抗vegf抗体の最適化変異体
|
|
ES2768957T3
(es)
|
2015-09-24 |
2020-06-24 |
Abvitro Llc |
Composiciones de anticuerpos contra el VIH y métodos de uso
|
|
SG10202007764TA
(en)
|
2015-09-25 |
2020-09-29 |
Genentech Inc |
Anti-tigit antibodies and methods of use
|
|
AU2016332900C1
(en)
|
2015-09-29 |
2024-07-04 |
Amgen Inc. |
ASGR inhibitors
|
|
AR106188A1
(es)
|
2015-10-01 |
2017-12-20 |
Hoffmann La Roche |
Anticuerpos anti-cd19 humano humanizados y métodos de utilización
|
|
WO2017055385A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Anti-cd3xgd2 bispecific t cell activating antigen binding molecules
|
|
MY206406A
(en)
|
2015-10-02 |
2024-12-16 |
Hoffmann La Roche |
Bispecific antibodies specific for a costimulatory tnf receptor
|
|
JP7044700B2
(ja)
|
2015-10-02 |
2022-03-30 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
二重特異性抗ceaxcd3 t細胞活性化抗原結合分子
|
|
CR20180243A
(es)
|
2015-10-02 |
2018-07-31 |
Genentech Inc |
Conjugados de anticuerpo-fármaco de pirrolobenzodiazepina y métodos de uso
|
|
US20180282410A1
(en)
|
2015-10-02 |
2018-10-04 |
Hoffmann-La Roche Inc. |
Anti-cd3xrob04 bispecific t cell activating antigen binding molecules
|
|
EP3356407B1
(en)
|
2015-10-02 |
2021-11-03 |
F. Hoffmann-La Roche AG |
Bispecific anti-cd19xcd3 t cell activating antigen binding molecules
|
|
MA43028B1
(fr)
|
2015-10-02 |
2021-09-30 |
Hoffmann La Roche |
Anticorps bispécifiques pour pd1 et tim3
|
|
CN108290958B
(zh)
*
|
2015-10-02 |
2021-12-28 |
豪夫迈·罗氏有限公司 |
多特异性抗体
|
|
CN108139394B
(zh)
|
2015-10-02 |
2020-10-30 |
豪夫迈·罗氏有限公司 |
用于确定同时结合的基于细胞的fret测定法
|
|
EP3150637A1
(en)
|
2015-10-02 |
2017-04-05 |
F. Hoffmann-La Roche AG |
Multispecific antibodies
|
|
SI3356404T1
(sl)
|
2015-10-02 |
2021-11-30 |
F. Hoffmann-La Roche Ag |
Protitelesa proti PD1 in postopki uporabe
|
|
WO2017055388A2
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Bispecific t cell activating antigen binding molecules
|
|
WO2017055392A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Anti-cd3xcd44v6 bispecific t cell activating antigen binding molecules
|
|
WO2017055393A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Anti-cd3xtim-3 bispecific t cell activating antigen binding molecules
|
|
US20170096485A1
(en)
|
2015-10-02 |
2017-04-06 |
Hoffmann-La Roche Inc. |
Bispecific t cell activating antigen binding molecules
|
|
PE20181349A1
(es)
|
2015-10-07 |
2018-08-22 |
Hoffmann La Roche |
Anticuerpos biespecificos con tetravalencia para un receptor de fnt coestimulador
|
|
CN108283001B
(zh)
|
2015-10-08 |
2022-08-19 |
酵活有限公司 |
包含κ和λ轻链的抗原结合多肽构建体及其用途
|
|
KR101851380B1
(ko)
|
2015-10-12 |
2018-04-23 |
아주대학교산학협력단 |
효모접합을 이용한 항체 ch3 도메인 이종이중체 돌연변이쌍 제조 방법 및 이에 의하여 제조된 ch3 돌연변이체 쌍
|
|
MA43354A
(fr)
|
2015-10-16 |
2018-08-22 |
Genentech Inc |
Conjugués médicamenteux à pont disulfure encombré
|
|
JP6852065B2
(ja)
|
2015-10-20 |
2021-03-31 |
ジェネンテック, インコーポレイテッド |
カリケアマイシン−抗体−薬物コンジュゲート及び使用方法
|
|
JP7296728B2
(ja)
|
2015-10-23 |
2023-06-23 |
メルス ナムローゼ フェンノートシャップ |
癌の成長を抑制する結合分子
|
|
EP3184547A1
(en)
|
2015-10-29 |
2017-06-28 |
F. Hoffmann-La Roche AG |
Anti-tpbg antibodies and methods of use
|
|
EP4015533A1
(en)
|
2015-10-29 |
2022-06-22 |
F. Hoffmann-La Roche AG |
Anti-variant fc-region antibodies and methods of use
|
|
BR112018007703A2
(pt)
|
2015-10-30 |
2018-11-06 |
Genentech Inc |
anticorpos, ácido nucleico isolado, métodos de produção de um anticorpo e de tratamento de um distúrbio, composição farmacêutica, terapia de combinação e uso do anticorpo
|
|
TW201730211A
(zh)
|
2015-10-30 |
2017-09-01 |
建南德克公司 |
抗因子d抗體及結合物
|
|
JP7027321B2
(ja)
|
2015-11-03 |
2022-03-01 |
ヤンセン バイオテツク,インコーポレーテツド |
抗cd38抗体の皮下製剤及びその使用
|
|
WO2017079768A1
(en)
|
2015-11-08 |
2017-05-11 |
Genentech, Inc. |
Methods of screening for multispecific antibodies
|
|
EP3378488A4
(en)
|
2015-11-18 |
2019-10-30 |
Chugai Seiyaku Kabushiki Kaisha |
Method for enhancing humoral immune response
|
|
JP6931329B2
(ja)
|
2015-11-18 |
2021-09-01 |
中外製薬株式会社 |
免疫抑制機能を有する細胞に対するt細胞リダイレクト抗原結合分子を用いた併用療法
|
|
MX2018006333A
(es)
|
2015-12-01 |
2018-08-01 |
Genmab Bv |
Anticuerpos anti-receptor de muerte 5 (dr5) y metodos de uso de los mismos.
|
|
EP3387013B1
(en)
|
2015-12-07 |
2022-06-08 |
Xencor, Inc. |
Heterodimeric antibodies that bind cd3 and psma
|
|
IL313608A
(en)
|
2015-12-09 |
2024-08-01 |
Hoffmann La Roche |
Antibody against CD20 type II to reduce the formation of antibodies against drugs
|
|
EP3178848A1
(en)
|
2015-12-09 |
2017-06-14 |
F. Hoffmann-La Roche AG |
Type ii anti-cd20 antibody for reducing formation of anti-drug antibodies
|
|
CN108367069B
(zh)
|
2015-12-14 |
2022-08-23 |
宏观基因有限公司 |
对于pd-1和ctla-4具有免疫反应性的双特异性分子及其使用方法
|
|
CN106883297B
(zh)
*
|
2015-12-16 |
2019-12-13 |
苏州康宁杰瑞生物科技有限公司 |
基于ch3结构域的异二聚体分子、其制备方法及用途
|
|
CR20180365A
(es)
|
2015-12-16 |
2018-09-28 |
Amgen Inc |
PROTEÍNAS DE UNIÓN AL ANTÍGENO BISPECÍFICO DE ANTI-TL1A/ANTI-TNF-a Y SUS USOS
|
|
CN108495651A
(zh)
|
2015-12-17 |
2018-09-04 |
诺华股份有限公司 |
抗pd-1的抗体分子及其用途
|
|
KR20180087430A
(ko)
|
2015-12-17 |
2018-08-01 |
얀센 바이오테크 인코포레이티드 |
Hla-dr에 특이적으로 결합하는 항체 및 이의 용도
|
|
CN108697794A
(zh)
|
2015-12-17 |
2018-10-23 |
诺华股份有限公司 |
C-met抑制剂和抗pd-1抗体分子的组合及其用途
|
|
EA201891420A1
(ru)
|
2015-12-18 |
2019-02-28 |
Чугаи Сейяку Кабусики Кайся |
Антитела к миостатину, полипептиды, содержащие варианты fc-областей, и способы их применения
|
|
CN108401431B
(zh)
|
2015-12-18 |
2022-01-25 |
中外制药株式会社 |
抗-c5抗体及使用方法
|
|
PT3393504T
(pt)
|
2015-12-22 |
2025-12-30 |
Novartis Ag |
Recetor de antigénio quimérico (car) de mesotelina e anticorpo contra o inibidor de pd-l1 para utilização combinada em terapia anticancerígena
|
|
US20200270363A1
(en)
|
2015-12-25 |
2020-08-27 |
Chugai Seiyaku Kabushiki Kaisha |
Antibody having enhanced activity, and method for modifying same
|
|
CN108779182A
(zh)
*
|
2015-12-28 |
2018-11-09 |
麻省理工学院 |
具有恒定区突变的双特异性抗体及其用途
|
|
SG11201803989WA
(en)
|
2015-12-28 |
2018-06-28 |
Chugai Pharmaceutical Co Ltd |
Method for promoting efficiency of purification of fc region-containing polypeptide
|
|
BR112018011029A2
(pt)
|
2016-01-08 |
2018-11-21 |
Hoffmann La Roche |
métodos para tratar ou atrasar a progressão do câncer e para melhorar a função imune em um indivíduo com câncer, usos de um antagonista de ligação e de um anticorpo biespecífico, composições e kits
|
|
EP3405489A1
(en)
|
2016-01-20 |
2018-11-28 |
Genentech, Inc. |
High dose treatments for alzheimer's disease
|
|
EP3851457A1
(en)
|
2016-01-21 |
2021-07-21 |
Novartis AG |
Multispecific molecules targeting cll-1
|
|
US10899836B2
(en)
|
2016-02-12 |
2021-01-26 |
Janssen Pharmaceutica Nv |
Method of identifying anti-VISTA antibodies
|
|
WO2017151502A1
(en)
|
2016-02-29 |
2017-09-08 |
Genentech, Inc. |
Therapeutic and diagnostic methods for cancer
|
|
US12391759B2
(en)
|
2016-03-02 |
2025-08-19 |
Momenta Pharmaceuticals, Inc. |
Methods related to engineered Fc constructs
|
|
SG11201807489PA
(en)
|
2016-03-04 |
2018-09-27 |
Novartis Ag |
Cells expressing multiple chimeric antigen receptor (car) molecules and uses therefore
|
|
EP3431102A4
(en)
|
2016-03-14 |
2019-09-25 |
Chugai Seiyaku Kabushiki Kaisha |
CELL DAMAGING THERAPEUTIC MEDICAMENT FOR USE IN CANCER THERAPY
|
|
US11291721B2
(en)
|
2016-03-21 |
2022-04-05 |
Marengo Therapeutics, Inc. |
Multispecific and multifunctional molecules and uses thereof
|
|
JP7015244B2
(ja)
|
2016-03-22 |
2022-02-02 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
プロテアーゼ活性化t細胞二重特異性分子
|
|
WO2017162587A1
(en)
|
2016-03-22 |
2017-09-28 |
F. Hoffmann-La Roche Ag |
Protease-activated t cell bispecific molecules
|
|
EP3432924A1
(en)
|
2016-03-23 |
2019-01-30 |
Novartis AG |
Cell secreted minibodies and uses thereof
|
|
CN108700598A
(zh)
|
2016-03-25 |
2018-10-23 |
豪夫迈·罗氏有限公司 |
多路总抗体和抗体缀合的药物量化测定法
|
|
CN117986363A
(zh)
|
2016-03-31 |
2024-05-07 |
恩格姆生物制药公司 |
结合蛋白及其使用方法
|
|
US20170306027A1
(en)
|
2016-04-06 |
2017-10-26 |
Acceleron Pharma Inc. |
Alk7 antagonists and uses thereof
|
|
EP3443004A1
(en)
|
2016-04-14 |
2019-02-20 |
H. Hoffnabb-La Roche Ag |
Anti-rspo3 antibodies and methods of use
|
|
PE20190115A1
(es)
|
2016-04-15 |
2019-01-16 |
Immunext Inc |
Anticuerpos vista antihumanos y su uso
|
|
EP4656204A3
(en)
|
2016-04-15 |
2026-06-03 |
BioAtla, Inc. |
Anti-axl antibodies, antibody fragments and their immunoconjugates and uses thereof
|
|
WO2017181079A2
(en)
|
2016-04-15 |
2017-10-19 |
Genentech, Inc. |
Methods for monitoring and treating cancer
|
|
PL3443350T3
(pl)
|
2016-04-15 |
2021-05-31 |
F. Hoffmann-La Roche Ag |
Sposoby monitorowania i leczenia nowotworu
|
|
US20230071283A1
(en)
|
2016-04-15 |
2023-03-09 |
Aimee S. Payne |
Compositions and methods for selective protein expression
|
|
BR112018071283A2
(pt)
|
2016-04-20 |
2019-02-12 |
Regeneron Pharma |
célula, conjunto de vetores para expressar uma proteína de ligação a antígeno biespecífica em uma célula, conjunto de vetores, método, e, método para produção de uma proteína de ligação a antígeno.
|
|
US11530277B2
(en)
|
2016-04-20 |
2022-12-20 |
Regeneron Pharmaceuticals, Inc. |
Compositions and methods for making antibodies based on use of an expression-enhancing locus
|
|
AU2017255077B2
(en)
|
2016-04-28 |
2024-05-16 |
Chugai Seiyaku Kabushiki Kaisha |
Antibody-containing preparation
|
|
JP6675017B2
(ja)
|
2016-05-02 |
2020-04-01 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
コントースボディ−単鎖標的結合物質
|
|
KR20240115933A
(ko)
|
2016-05-04 |
2024-07-26 |
암젠 인크 |
T-조절 세포의 증식을 위한 인터류킨-2 뮤테인
|
|
JP7089483B2
(ja)
|
2016-05-11 |
2022-06-22 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
修飾された抗テネイシン抗体及び使用方法
|
|
EP3243836A1
(en)
|
2016-05-11 |
2017-11-15 |
F. Hoffmann-La Roche AG |
C-terminally fused tnf family ligand trimer-containing antigen binding molecules
|
|
EP3455254B1
(en)
|
2016-05-11 |
2021-07-07 |
F. Hoffmann-La Roche AG |
Antigen binding molecules comprising a tnf family ligand trimer and a tenascin binding moiety
|
|
EP3243832A1
(en)
|
2016-05-13 |
2017-11-15 |
F. Hoffmann-La Roche AG |
Antigen binding molecules comprising a tnf family ligand trimer and pd1 binding moiety
|
|
EP4122958A1
(en)
|
2016-05-13 |
2023-01-25 |
BioAtla, Inc. |
Anti-ror2 antibodies, antibody fragments, their immunoconjugates and uses thereof
|
|
CA3024465A1
(en)
|
2016-05-17 |
2017-11-23 |
Genentech, Inc. |
Stromal gene signatures for diagnosis and use in immunotherapy
|
|
CN109152843A
(zh)
|
2016-05-20 |
2019-01-04 |
豪夫迈·罗氏有限公司 |
Protac抗体缀合物及其使用方法
|
|
IL309293A
(en)
|
2016-05-23 |
2024-02-01 |
Momenta Pharmaceuticals Inc |
Compositions and methods relating to engineered FC constructs
|
|
MX2018014432A
(es)
|
2016-05-25 |
2019-04-01 |
Hoffmann La Roche |
Materiales y metodos relacionados con el diseño del regimen de dosificacion.
|
|
CA3025162A1
(en)
*
|
2016-05-26 |
2017-11-30 |
Qilu Puget Sound Biotherapeutics Corporation |
Mixtures of antibodies
|
|
CN109313200B
(zh)
|
2016-05-27 |
2022-10-04 |
豪夫迈·罗氏有限公司 |
用于表征位点特异性抗体-药物缀合物的生物分析性方法
|
|
EP3252078A1
(en)
|
2016-06-02 |
2017-12-06 |
F. Hoffmann-La Roche AG |
Type ii anti-cd20 antibody and anti-cd20/cd3 bispecific antibody for treatment of cancer
|
|
WO2017210617A2
(en)
|
2016-06-02 |
2017-12-07 |
Porter, David, L. |
Therapeutic regimens for chimeric antigen receptor (car)- expressing cells
|
|
JP7043425B2
(ja)
|
2016-06-06 |
2022-03-29 |
ジェネンテック, インコーポレイテッド |
シルベストロール抗体-薬物コンジュゲート及び使用方法
|
|
CA3026151A1
(en)
|
2016-06-14 |
2017-12-21 |
Xencor, Inc. |
Bispecific checkpoint inhibitor antibodies
|
|
CA3026518A1
(en)
|
2016-06-17 |
2017-12-21 |
Genentech, Inc. |
Purification of multispecific antibodies
|
|
TWI760396B
(zh)
|
2016-06-17 |
2022-04-11 |
日商中外製藥股份有限公司 |
抗肌抑素抗體及使用方法
|
|
JP7133477B2
(ja)
|
2016-06-24 |
2022-09-08 |
ジェネンテック, インコーポレイテッド |
抗ポリユビキチン多重特異性抗体
|
|
WO2018002181A1
(en)
|
2016-06-28 |
2018-01-04 |
Umc Utrecht Holding B.V. |
TREATMENT OF IgE-MEDIATED DISEASES WITH ANTIBODIES THAT SPECIFICALLY BIND CD38
|
|
RU2019102008A
(ru)
|
2016-06-28 |
2020-07-28 |
Ксенкор, Инк. |
Гетеродимерные антитела, которые связывают рецептор соматостатина 2-го типа
|
|
MA45554A
(fr)
|
2016-07-01 |
2019-05-08 |
Resolve Therapeutics Llc |
Fusions de binucléase optimisées.
|
|
JP6983824B2
(ja)
|
2016-07-04 |
2021-12-17 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
新規抗体フォーマット
|
|
BR112019000512A2
(pt)
|
2016-07-14 |
2019-04-24 |
Genmab A/S |
anticorpo, ácido nucleico, vetor de expressão, célula hospedeira, composição, métodos de tratamento de uma doença, para produzir um anticorpo biespecífico e para detectar se a reticulação entre as células que expressam cd40 e cd137 ocorre em uma amostra, uso de um anticorpo multiespecífico, e, kit
|
|
EP3484455A2
(en)
|
2016-07-15 |
2019-05-22 |
Novartis AG |
Treatment and prevention of cytokine release syndrome using a chimeric antigen receptor in combination with a kinase inhibitor
|
|
AU2017296040C1
(en)
|
2016-07-15 |
2023-06-22 |
Acceleron Pharma Inc. |
Compositions and methods for treating pulmonary hypertension
|
|
RU2745648C2
(ru)
*
|
2016-07-19 |
2021-03-30 |
Ибентрус, Инк. |
Биспецифические белки и способы их получения
|
|
WO2018014260A1
(en)
|
2016-07-20 |
2018-01-25 |
Nanjing Legend Biotech Co., Ltd. |
Multispecific antigen binding proteins and methods of use thereof
|
|
US11312745B2
(en)
|
2016-07-22 |
2022-04-26 |
Amgen Inc. |
Methods of purifying Fc-containing proteins
|
|
LT3490582T
(lt)
|
2016-07-27 |
2024-07-25 |
Acceleron Pharma Inc. |
Kompozicijos, skirtos naudoti gydant mielofibrozę
|
|
KR20230100748A
(ko)
|
2016-07-28 |
2023-07-05 |
노파르티스 아게 |
키메라 항원 수용체 및 pd-1 억제제의 조합 요법
|
|
CA3027018A1
(en)
|
2016-07-29 |
2018-02-01 |
Chugai Seiyaku Kabushiki Kaisha |
Bispecific antibody exhibiting increased alternative fviii-cofactor-function activity
|
|
SG11201900885VA
(en)
|
2016-08-01 |
2019-02-27 |
Novartis Ag |
Treatment of cancer using a chimeric antigen receptor in combination with an inhibitor of a pro-m2 macrophage molecule
|
|
WO2018026942A1
(en)
*
|
2016-08-02 |
2018-02-08 |
Merrimack Pharmaceuticals, Inc. |
Heteromeric polypeptides
|
|
EP3494139B1
(en)
|
2016-08-05 |
2022-01-12 |
F. Hoffmann-La Roche AG |
Multivalent and multiepitopic anitibodies having agonistic activity and methods of use
|
|
CN116271014A
(zh)
|
2016-08-05 |
2023-06-23 |
中外制药株式会社 |
用于预防或治疗il-8相关疾病的组合物
|
|
EP3511340B1
(en)
|
2016-08-10 |
2024-10-02 |
Ajou University Industry-Academic Cooperation Foundation |
Heterodimeric fc-fused cytokine and pharmaceutical composition comprising the same
|
|
PL3896091T3
(pl)
|
2016-08-10 |
2024-04-29 |
Legend Biotech Ireland Limited |
Chimeryczne receptory antygenowe nakierowane na bcma i sposoby ich zastosowania
|
|
WO2018031662A1
(en)
|
2016-08-11 |
2018-02-15 |
Genentech, Inc. |
Pyrrolobenzodiazepine prodrugs and antibody conjugates thereof
|
|
WO2018038046A1
(ja)
|
2016-08-22 |
2018-03-01 |
中外製薬株式会社 |
ヒトgpc3ポリペプチドを発現する遺伝子改変非ヒト動物
|
|
US10793632B2
(en)
|
2016-08-30 |
2020-10-06 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
|
SG10201607778XA
(en)
|
2016-09-16 |
2018-04-27 |
Chugai Pharmaceutical Co Ltd |
Anti-Dengue Virus Antibodies, Polypeptides Containing Variant Fc Regions, And Methods Of Use
|
|
CN116731197A
(zh)
|
2016-09-19 |
2023-09-12 |
豪夫迈·罗氏有限公司 |
基于补体因子的亲和层析
|
|
TWI787203B
(zh)
|
2016-09-23 |
2022-12-21 |
美商建南德克公司 |
Il-13拮抗劑用於治療異位性皮炎之用途
|
|
SG10201913263SA
(en)
|
2016-09-29 |
2020-03-30 |
Beijing Hanmi Pharmaceutical Co Ltd |
Heterodimeric immunoglobulin constructs and preparation methods thereof
|
|
CN109843926B
(zh)
|
2016-09-30 |
2023-01-20 |
豪夫迈·罗氏有限公司 |
针对cd3的双特异性抗体
|
|
JP6785372B2
(ja)
|
2016-09-30 |
2020-11-18 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
多重特異性分子の機能分析のためのsprに基づく二重結合アッセイ
|
|
WO2018067740A1
(en)
|
2016-10-05 |
2018-04-12 |
Acceleron Pharma, Inc. |
Compositions and method for treating kidney disease
|
|
AU2017338916B2
(en)
*
|
2016-10-05 |
2022-03-24 |
Acceleron Pharma Inc. |
Variant ActRIIB proteins and uses thereof
|
|
CN110678195A
(zh)
|
2016-10-05 |
2020-01-10 |
阿塞勒隆制药公司 |
ALK4:ActRIIB异多聚体及其用途
|
|
JP7050770B2
(ja)
|
2016-10-05 |
2022-04-08 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
抗体薬物コンジュゲートの調製方法
|
|
KR102804118B1
(ko)
|
2016-10-06 |
2025-05-09 |
제넨테크, 인크. |
암에 대한 치료 및 진단 방법
|
|
JP7467117B2
(ja)
|
2016-10-07 |
2024-04-15 |
ノバルティス アーゲー |
癌の治療のためのキメラ抗原受容体
|
|
WO2018068201A1
(en)
|
2016-10-11 |
2018-04-19 |
Nanjing Legend Biotech Co., Ltd. |
Single-domain antibodies and variants thereof against ctla-4
|
|
MX2019004327A
(es)
|
2016-10-14 |
2019-10-14 |
Xencor Inc |
Proteinas de fusion heterodimericas biespecificas que contienen proteinas de fusion fc il-15/il-15ra y fragmentos de anticuerpo pd-1.
|
|
DK3529269T3
(da)
|
2016-10-19 |
2026-02-23 |
Invenra Inc |
Antistof-konstruktioner
|
|
EP3532091A2
(en)
|
2016-10-29 |
2019-09-04 |
H. Hoffnabb-La Roche Ag |
Anti-mic antibidies and methods of use
|
|
EP3535291A1
(en)
|
2016-11-01 |
2019-09-11 |
Genmab B.V. |
Polypeptide variants and uses thereof
|
|
JP2019534044A
(ja)
|
2016-11-08 |
2019-11-28 |
クイル ピュージェット サウンド バイオセラピューティクス コーポレーション |
抗pd1および抗ctla4抗体
|
|
US11912750B2
(en)
|
2016-11-10 |
2024-02-27 |
Keros Therapeutics, Inc. |
GDNF fusion polypeptides and methods of use thereof
|
|
CA3043184A1
(en)
|
2016-11-10 |
2018-05-17 |
Keros Therapeutics, Inc. |
Activin receptor type iia variants and methods of use thereof
|
|
AU2017356317A1
(en)
|
2016-11-14 |
2019-05-30 |
Amgen Inc. |
Bispecific or biparatopic antigen binding proteins and uses thereof
|
|
EP3541843A1
(en)
|
2016-11-15 |
2019-09-25 |
Genentech, Inc. |
Dosing for treatment with anti-cd20/anti-cd3 bispecific antibodies
|
|
WO2018090950A1
(zh)
|
2016-11-18 |
2018-05-24 |
北京韩美药品有限公司 |
抗pd‐1/抗her2天然抗体结构样异源二聚体形式双特异抗体及其制备
|
|
TW201829463A
(zh)
|
2016-11-18 |
2018-08-16 |
瑞士商赫孚孟拉羅股份公司 |
抗hla-g抗體及其用途
|
|
JOP20190100A1
(ar)
|
2016-11-19 |
2019-05-01 |
Potenza Therapeutics Inc |
بروتينات ربط مولد ضد مضاد لـ gitr وطرق استخدامها
|
|
AU2017363309A1
(en)
|
2016-11-23 |
2019-07-11 |
Bioverativ Therapeutics Inc. |
Mono- and bispecific antibodies binding to coagulation factor IX and coagulation factor X
|
|
EP3551655A2
(en)
|
2016-12-07 |
2019-10-16 |
Genentech, Inc. |
Anti-tau antibodies and methods of their use
|
|
EP3551220B1
(en)
|
2016-12-07 |
2025-01-29 |
Genentech, Inc. |
Anti-tau antibodies and methods of use
|
|
WO2018108759A1
(en)
|
2016-12-13 |
2018-06-21 |
F. Hoffmann-La Roche Ag |
Method to determine the presence of a target antigen in a tumor sample
|
|
JP7125400B2
(ja)
|
2016-12-19 |
2022-08-24 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
標的化4-1bb(cd137)アゴニストとの併用療法
|
|
KR102692708B1
(ko)
|
2016-12-20 |
2024-08-07 |
에프. 호프만-라 로슈 아게 |
항-cd20/항-cd3 이중특이성 항체 및 4-1bb(cd137) 작용물질의 병용 요법
|
|
EP3559248B2
(en)
|
2016-12-21 |
2024-11-20 |
F. Hoffmann-La Roche AG |
In vitro glycoengineering of antibodies
|
|
CN110088625B
(zh)
|
2016-12-21 |
2023-11-03 |
豪夫迈·罗氏有限公司 |
用于确定抗体或配体结合和功能的测定法
|
|
MX2019007411A
(es)
|
2016-12-21 |
2019-08-29 |
Hoffmann La Roche |
Reuso de enzimas en glucomanipulacion in vitro de anticuerpos.
|
|
MX2019006123A
(es)
|
2016-12-21 |
2019-08-12 |
Hoffmann La Roche |
Metodo para glicomanipulacion in vitro de anticuerpos.
|
|
EP3360898A1
(en)
|
2017-02-14 |
2018-08-15 |
Boehringer Ingelheim International GmbH |
Bispecific anti-tnf-related apoptosis-inducing ligand receptor 2 and anti-cadherin 17 binding molecules for the treatment of cancer
|
|
EP3559032A1
(en)
|
2016-12-23 |
2019-10-30 |
Innate Pharma |
Heterodimeric antigen binding proteins
|
|
CA3047070A1
(en)
|
2017-01-03 |
2018-07-12 |
F.Hoffmann-La Roche Ag |
Bispecific antigen binding molecules comprising anti-4-1bb clone 20h4.9
|
|
CN110650748B
(zh)
|
2017-01-06 |
2024-01-02 |
动量制药公司 |
与经工程改造的Fc构建体相关的组合物和方法
|
|
TW201831517A
(zh)
|
2017-01-12 |
2018-09-01 |
美商優瑞科生物技術公司 |
靶向組織蛋白h3肽/mhc複合體之構築體及其用途
|
|
US11535662B2
(en)
|
2017-01-26 |
2022-12-27 |
Novartis Ag |
CD28 compositions and methods for chimeric antigen receptor therapy
|
|
CN110234355B
(zh)
|
2017-02-01 |
2021-11-09 |
浙江时迈药业有限公司 |
单体人IgG1 Fc和双特异性抗体
|
|
TW201837174A
(zh)
|
2017-02-07 |
2018-10-16 |
日商第一三共股份有限公司 |
抗gprc5d抗體及包含該抗體之分子
|
|
CN110944651A
(zh)
|
2017-02-08 |
2020-03-31 |
蜻蜓疗法股份有限公司 |
用于自然杀伤细胞激活的多特异性结合蛋白及其治疗癌症的治疗性用途
|
|
BR112019015900A2
(pt)
|
2017-02-10 |
2020-04-07 |
Genmab B.V. |
polipeptídeo, métodos para aumentar a atividade agonística de um polipeptídeo, para aumentar a atividade de cdc de um polipeptídeo e de tratamento de um indivíduo tendo uma doença, composição, kit de partes, e, uso de um polipeptídeo ou uma composição
|
|
CN116715775A
(zh)
|
2017-02-10 |
2023-09-08 |
豪夫迈·罗氏有限公司 |
抗类胰蛋白酶抗体、其组合物及其用途
|
|
AU2018219348A1
(en)
*
|
2017-02-10 |
2019-08-29 |
Dragonfly Therapeutics, Inc. |
Proteins binding BCMA, NKG2D and CD16
|
|
WO2018151820A1
(en)
|
2017-02-16 |
2018-08-23 |
Elstar Therapeutics, Inc. |
Multifunctional molecules comprising a trimeric ligand and uses thereof
|
|
EP4273258A3
(en)
|
2017-02-20 |
2024-01-17 |
Dragonfly Therapeutics, Inc. |
Proteins binding her2, nkg2d and cd16
|
|
JP7556687B2
(ja)
*
|
2017-02-24 |
2024-09-26 |
中外製薬株式会社 |
薬学的組成物、抗原結合分子、治療方法、およびスクリーニング方法
|
|
MX2019010295A
(es)
|
2017-03-01 |
2019-11-21 |
Genentech Inc |
Métodos de diagnóstico y terapéuticos para el cáncer.
|
|
EP3589650A1
(en)
|
2017-03-02 |
2020-01-08 |
Novartis AG |
Engineered heterodimeric proteins
|
|
LT3592769T
(lt)
|
2017-03-09 |
2024-08-26 |
Genmab A/S |
Antikūnai, atpažįstantys pd-l1
|
|
KR20190124270A
(ko)
|
2017-03-10 |
2019-11-04 |
에프. 호프만-라 로슈 아게 |
다중특이적 항체의 생산 방법
|
|
JP7216006B2
(ja)
|
2017-03-22 |
2023-01-31 |
ジェネンテック, インコーポレイテッド |
ヒドロゲル架橋ヒアルロン酸プロドラッグ組成物及び方法
|
|
EP3600442A1
(en)
|
2017-03-22 |
2020-02-05 |
Genentech, Inc. |
Optimized antibody compositions for treatment of ocular disorders
|
|
CN117205311A
(zh)
|
2017-03-28 |
2023-12-12 |
基因泰克公司 |
治疗神经退行性疾病的方法
|
|
WO2018178055A1
(en)
|
2017-03-29 |
2018-10-04 |
F. Hoffmann-La Roche Ag |
Bispecific antigen binding molecule for a costimulatory tnf receptor
|
|
WO2018178076A1
(en)
|
2017-03-29 |
2018-10-04 |
F. Hoffmann-La Roche Ag |
Bispecific antigen binding molecule for a costimulatory tnf receptor
|
|
CN119285787A
(zh)
|
2017-03-31 |
2025-01-10 |
健玛保控股有限公司 |
双特异性抗cd37抗体、单克隆抗cd37抗体及其使用方法
|
|
JP7737220B2
(ja)
|
2017-03-31 |
2025-09-10 |
メルス ナムローゼ フェンノートシャップ |
NRG1融合遺伝子を有する細胞の処置における使用のためのErbB-2及びErbB3結合二重特異性抗体
|
|
JP7209298B2
(ja)
|
2017-03-31 |
2023-01-20 |
公立大学法人奈良県立医科大学 |
血液凝固第viii因子の機能を代替する多重特異性抗原結合分子を含有する、血液凝固第ix因子異常症の予防および/または治療に用いられる医薬組成物
|
|
KR102629905B1
(ko)
|
2017-04-01 |
2024-01-30 |
베이징 한미 파마슈티컬 컴퍼니 리미티드 |
항-pd-l1/항-pd-1 천연 항체 구조-유사 헤테로다이머 이중특이성 항체 및 그의 제조
|
|
KR102461885B1
(ko)
|
2017-04-03 |
2022-11-03 |
에프. 호프만-라 로슈 아게 |
항-pd-1 항체와 돌연변이 il-2 또는 il-15의 면역접합체
|
|
PE20200010A1
(es)
|
2017-04-03 |
2020-01-06 |
Hoffmann La Roche |
Anticuerpos que se unen a steap-1
|
|
JP7148539B2
(ja)
|
2017-04-03 |
2022-10-05 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
免疫抱合体
|
|
KR20200020662A
(ko)
|
2017-04-03 |
2020-02-26 |
온콜로지, 인크. |
면역-종양학 제제와 함께 ps-표적화 항체를 사용하여 암을 치료하는 방법
|
|
CN110402255B
(zh)
|
2017-04-04 |
2022-12-02 |
豪夫迈·罗氏有限公司 |
新颖的能够特异性结合cd40和fap的双特异性抗原结合分子
|
|
UA128387C2
(uk)
|
2017-04-05 |
2024-07-03 |
Ф. Хоффманн-Ля Рош Аг |
Антитіло до lag3
|
|
CA3052532A1
(en)
|
2017-04-05 |
2018-10-11 |
F. Hoffmann-La Roche Ag |
Bispecific antibodies specifically binding to pd1 and lag3
|
|
MY200973A
(en)
|
2017-04-11 |
2024-01-26 |
Inhibrx Inc |
Multispecific Polypeptide Constructs Having Constrained Cd3 Binding And Methods Of Using The Same
|
|
KR20190136076A
(ko)
|
2017-04-13 |
2019-12-09 |
에프. 호프만-라 로슈 아게 |
암 치료 방법에 사용하기 위한 인터루킨-2 면역접합체, cd40 작용제 및 임의적인 pd-1 축 결합 길항제
|
|
JOP20190248A1
(ar)
|
2017-04-21 |
2019-10-20 |
Amgen Inc |
بروتينات ربط مولد ضد trem2 واستخداماته
|
|
TW201841656A
(zh)
|
2017-04-21 |
2018-12-01 |
美商建南德克公司 |
Klk5拮抗劑用於治療疾病之用途
|
|
EP3615574B1
(en)
|
2017-04-26 |
2026-06-24 |
Eureka Therapeutics, Inc. |
Constructs specifically recognizing glypican 3 and uses thereof
|
|
EP3615068A1
(en)
|
2017-04-28 |
2020-03-04 |
Novartis AG |
Bcma-targeting agent, and combination therapy with a gamma secretase inhibitor
|
|
EP3615055A1
(en)
|
2017-04-28 |
2020-03-04 |
Novartis AG |
Cells expressing a bcma-targeting chimeric antigen receptor, and combination therapy with a gamma secretase inhibitor
|
|
EP3625264B9
(en)
|
2017-05-17 |
2023-10-25 |
Merus N.V. |
Combination of an erbb-2/erbb-3 bispecific antibody with endocrine therapy for breast cancer
|
|
EP3630836A1
(en)
|
2017-05-31 |
2020-04-08 |
Elstar Therapeutics, Inc. |
Multispecific molecules that bind to myeloproliferative leukemia (mpl) protein and uses thereof
|
|
JP2020521791A
(ja)
|
2017-06-02 |
2020-07-27 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
がんの治療のためのii型抗cd20抗体及び抗cd20/cd30二重特異性抗体
|
|
EP3635005A1
(en)
|
2017-06-07 |
2020-04-15 |
Genmab B.V. |
Therapeutic antibodies based on mutated igg hexamers
|
|
UY37758A
(es)
|
2017-06-12 |
2019-01-31 |
Novartis Ag |
Método de fabricación de anticuerpos biespecíficos, anticuerpos biespecíficos y uso terapéutico de dichos anticuerpos
|
|
MX2019015885A
(es)
|
2017-06-22 |
2020-09-10 |
Novartis Ag |
Moleculas de anticuerpo que se unen a cd73 y usos de las mismas.
|
|
CN111050791A
(zh)
|
2017-06-27 |
2020-04-21 |
诺华股份有限公司 |
用于抗tim-3抗体的给药方案及其用途
|
|
AU2018291497A1
(en)
|
2017-06-30 |
2020-01-16 |
Xencor, Inc. |
Targeted heterodimeric Fc fusion proteins containing IL-15/IL-15Ra and antigen binding domains
|
|
AR112603A1
(es)
|
2017-07-10 |
2019-11-20 |
Lilly Co Eli |
Anticuerpos biespecíficos inhibidores de punto de control
|
|
SG10201913147WA
(en)
|
2017-07-11 |
2020-02-27 |
Compass Therapeutics Llc |
Agonist antibodies that bind human cd137 and uses thereof
|
|
WO2019018730A1
(en)
|
2017-07-20 |
2019-01-24 |
Novartis Ag |
DOSAGE REGIMES FOR ANTI-LAG3 ANTIBODIES AND USES THEREOF
|
|
AU2018304458B2
(en)
|
2017-07-21 |
2021-12-09 |
Foundation Medicine, Inc. |
Therapeutic and diagnostic methods for cancer
|
|
EP3658589B1
(en)
|
2017-07-26 |
2023-09-27 |
Forty Seven, Inc. |
Anti-sirp-alpha antibodies and related methods
|
|
KR20250020679A
(ko)
|
2017-08-04 |
2025-02-11 |
젠맵 에이/에스 |
Pd-l1 및 cd137에 결합하는 결합제 및 그의 용도
|
|
RS66708B9
(sr)
|
2017-08-09 |
2025-08-29 |
Merus Nv |
Antitela koja se vezuju za egfr i cmet
|
|
WO2019033043A2
(en)
|
2017-08-11 |
2019-02-14 |
Genentech, Inc. |
ANTI-CD8 ANTIBODIES AND USES THEREOF
|
|
CN111315767B
(zh)
|
2017-08-22 |
2025-03-18 |
萨纳生物有限责任公司 |
可溶性干扰素受体及其用途
|
|
CA3071236A1
(en)
|
2017-09-29 |
2019-04-04 |
Chugai Seiyaku Kabushiki Kaisha |
Multispecific antigen-binding molecule having blood coagulation factor viii (fviii) cofactor function-substituting activity, and pharmaceutical formulation containing said moleculeas active ingredient
|
|
CN119264274A
(zh)
|
2017-10-12 |
2025-01-07 |
免疫苏醒公司 |
Vegfr-抗体轻链融合蛋白
|
|
WO2019077092A1
(en)
*
|
2017-10-20 |
2019-04-25 |
F. Hoffmann-La Roche Ag |
METHOD FOR GENERATING MULTISPECIFIC ANTIBODIES FROM MONOSPECIFIC ANTIBODIES
|
|
IL274071B2
(en)
*
|
2017-10-30 |
2025-10-01 |
Hoffmann La Roche |
Method for generating in vivo multispecific antibodies from monospecific antibodies
|
|
US11718679B2
(en)
|
2017-10-31 |
2023-08-08 |
Compass Therapeutics Llc |
CD137 antibodies and PD-1 antagonists and uses thereof
|
|
CN111295392A
(zh)
|
2017-11-01 |
2020-06-16 |
豪夫迈·罗氏有限公司 |
Compbody–多价靶结合物
|
|
KR20260090008A
(ko)
|
2017-11-01 |
2026-06-16 |
추가이 세이야쿠 가부시키가이샤 |
생물 활성이 저하된 항체 배리언트 및 아이소폼
|
|
BR112020008031A2
(pt)
|
2017-11-01 |
2020-10-27 |
F. Hoffmann-La Roche Ag |
anticorpo multiespecíficos, método para a preparação do anticorpo multiespecífico, conjunto de ácidos nucleicos, vetor de expressão, célula hospedeira e composição farmacêutica
|
|
PE20210844A1
(es)
|
2017-11-01 |
2021-05-10 |
Hoffmann La Roche |
Contorsbodies 2 + biespecificos
|
|
CN111246884A
(zh)
|
2017-11-01 |
2020-06-05 |
豪夫迈·罗氏有限公司 |
新颖的含有tnf家族配体三聚体的抗原结合分子
|
|
EP3704155A2
(en)
|
2017-11-01 |
2020-09-09 |
F. Hoffmann-La Roche AG |
Combination therapy with targeted ox40 agonists
|
|
WO2019090263A1
(en)
|
2017-11-06 |
2019-05-09 |
Genentech, Inc. |
Diagnostic and therapeutic methods for cancer
|
|
AU2018366199A1
(en)
|
2017-11-08 |
2020-05-28 |
Xencor, Inc. |
Bispecific and monospecific antibodies using novel anti-PD-1 sequences
|
|
US10981992B2
(en)
|
2017-11-08 |
2021-04-20 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
|
EP3706777B1
(en)
|
2017-11-09 |
2024-05-22 |
Keros Therapeutics, Inc. |
Activin receptor type iia variants and methods of use thereof
|
|
EP4640703A3
(en)
|
2017-11-14 |
2026-04-08 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-c1s antibodies and methods of use
|
|
MX2020004756A
(es)
|
2017-11-16 |
2020-08-20 |
Novartis Ag |
Terapias de combinacion.
|
|
EP3713961A2
(en)
|
2017-11-20 |
2020-09-30 |
Compass Therapeutics LLC |
Cd137 antibodies and tumor antigen-targeting antibodies and uses thereof
|
|
EP3713959A1
(en)
|
2017-11-21 |
2020-09-30 |
Innate Pharma |
Multispecific antigen binding proteins
|
|
JP7765181B2
(ja)
|
2017-12-19 |
2025-11-06 |
ゼンコア インコーポレイテッド |
改変されたil-2 fc融合タンパク質
|
|
EP3502140A1
(en)
|
2017-12-21 |
2019-06-26 |
F. Hoffmann-La Roche AG |
Combination therapy of tumor targeted icos agonists with t-cell bispecific molecules
|
|
PE20201149A1
(es)
|
2017-12-21 |
2020-10-26 |
Hoffmann La Roche |
Anticuerpos de union a hla-a2/wt1
|
|
US20190211098A1
(en)
|
2017-12-22 |
2019-07-11 |
Genentech, Inc. |
Use of pilra binding agents for treatment of a disease
|
|
US11945839B2
(en)
|
2017-12-22 |
2024-04-02 |
Hoffmann-La Roche Inc. |
Depletion of light chain mispaired antibody variants by hydrophobic interaction chromatography
|
|
KR102845020B1
(ko)
|
2017-12-28 |
2025-08-12 |
난징 레전드 바이오테크 씨오., 엘티디. |
Pd-l1에 대한 항체 및 변이체
|
|
SG11202004158QA
(en)
|
2017-12-28 |
2020-06-29 |
Nanjing Legend Biotech Co Ltd |
Single-domain antibodies and variants thereof against tigit
|
|
WO2019129677A1
(en)
|
2017-12-29 |
2019-07-04 |
F. Hoffmann-La Roche Ag |
Anti-vegf antibodies and methods of use
|
|
CN111886246B
(zh)
|
2017-12-29 |
2024-12-17 |
艾莱克特有限责任公司 |
抗tmem106b抗体及其使用方法
|
|
KR20240134250A
(ko)
|
2018-01-04 |
2024-09-06 |
아이코닉 테라퓨틱스, 인코포레이티드 |
항-조직 인자 항체, 항체-약물 결합체, 및 관련 방법
|
|
US12247060B2
(en)
|
2018-01-09 |
2025-03-11 |
Marengo Therapeutics, Inc. |
Calreticulin binding constructs and engineered T cells for the treatment of diseases
|
|
IL275536B2
(en)
|
2018-01-12 |
2025-06-01 |
Genzyme Corp |
Methods for quantification of polypeptides
|
|
CA3084518A1
(en)
|
2018-01-15 |
2019-07-18 |
Nanjing Legend Biotech Co., Ltd. |
Single-domain antibodies and variants thereof against pd-1
|
|
EP3740505A1
(en)
|
2018-01-16 |
2020-11-25 |
Lakepharma Inc. |
Bispecific antibody that binds cd3 and another target
|
|
US12649798B2
(en)
|
2018-01-24 |
2026-06-09 |
Genmab B.V. |
Polypeptide variants and uses thereof
|
|
JP2021511793A
(ja)
|
2018-01-31 |
2021-05-13 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
Lag3に結合する抗原結合部位を含む二重特異性抗体
|
|
AU2019215031C1
(en)
|
2018-01-31 |
2026-02-26 |
Novartis Ag |
Combination therapy using a chimeric antigen receptor
|
|
EP3746476A1
(en)
|
2018-01-31 |
2020-12-09 |
Alector LLC |
Anti-ms4a4a antibodies and methods of use thereof
|
|
EP3746484A4
(en)
|
2018-01-31 |
2021-11-17 |
Alector LLC |
ANTI-MS4A6A ANTIBODY AND METHOD OF USING THEREOF
|
|
JP2021511782A
(ja)
|
2018-01-31 |
2021-05-13 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
安定化された免疫グロブリンドメイン
|
|
WO2019148410A1
(en)
|
2018-02-01 |
2019-08-08 |
Merck Sharp & Dohme Corp. |
Anti-pd-1 antibodies
|
|
WO2019148412A1
(en)
|
2018-02-01 |
2019-08-08 |
Merck Sharp & Dohme Corp. |
Anti-pd-1/lag3 bispecific antibodies
|
|
CN111699004A
(zh)
|
2018-02-06 |
2020-09-22 |
豪夫迈·罗氏有限公司 |
眼科疾病的治疗
|
|
CA3090244A1
(en)
|
2018-02-08 |
2019-08-15 |
Dragonfly Therapeutics, Inc. |
Antibody variable domains targeting the nkg2d receptor
|
|
CR20200391A
(es)
|
2018-02-08 |
2020-10-19 |
Genentech Inc |
Moléculas biespecíficas de unión al antígeno y métodos de uso
|
|
MX2020008333A
(es)
|
2018-02-08 |
2020-09-21 |
Dragonfly Therapeutics Inc |
Terapia de combinacion del cancer que incluye proteinas de union multiespecificas que activan a las celulas asesinas naturales.
|
|
WO2019153200A1
(zh)
|
2018-02-08 |
2019-08-15 |
北京韩美药品有限公司 |
抗pd-1/抗her2天然抗体结构样异源二聚体形式双特异抗体及其制备
|
|
KR20220098056A
(ko)
|
2018-02-09 |
2022-07-08 |
제넨테크, 인크. |
비만 세포 매개 염증성 질환에 대한 치료 및 진단 방법
|
|
TWI829667B
(zh)
|
2018-02-09 |
2024-01-21 |
瑞士商赫孚孟拉羅股份公司 |
結合gprc5d之抗體
|
|
US11827697B2
(en)
|
2018-02-11 |
2023-11-28 |
Beijing Hanmi Pharmaceutical Co., Ltd. |
Anti-PD-1/anti-VEGF natural antibody structure like heterodimeric form bispecific antibody and preparation thereof
|
|
WO2019160007A1
(ja)
|
2018-02-14 |
2019-08-22 |
中外製薬株式会社 |
抗原結合分子および組合せ
|
|
CN112119093A
(zh)
|
2018-02-20 |
2020-12-22 |
蜻蜓治疗公司 |
结合cd33、nkg2d和cd16的多特异性结合蛋白和使用方法
|
|
MA52152A
(fr)
|
2018-03-12 |
2021-01-20 |
Genmab As |
Anticorps
|
|
PL3765489T3
(pl)
|
2018-03-13 |
2025-02-10 |
F. Hoffmann-La Roche Ag |
Terapeutyczne połączenie agonistów 4-1BB z przeciwciałami anty-CD20
|
|
TWI841551B
(zh)
|
2018-03-13 |
2024-05-11 |
瑞士商赫孚孟拉羅股份公司 |
使用靶向4-1bb (cd137)之促效劑的組合療法
|
|
US20200040103A1
(en)
|
2018-03-14 |
2020-02-06 |
Genentech, Inc. |
Anti-klk5 antibodies and methods of use
|
|
EP3765516A2
(en)
|
2018-03-14 |
2021-01-20 |
Elstar Therapeutics, Inc. |
Multifunctional molecules and uses thereof
|
|
EP3765517A1
(en)
|
2018-03-14 |
2021-01-20 |
Elstar Therapeutics, Inc. |
Multifunctional molecules that bind to calreticulin and uses thereof
|
|
TWI827585B
(zh)
|
2018-03-15 |
2024-01-01 |
日商中外製藥股份有限公司 |
對茲卡病毒具有交叉反應性的抗登革病毒抗體及其使用方法
|
|
JP2021519073A
(ja)
|
2018-03-29 |
2021-08-10 |
ジェネンテック, インコーポレイテッド |
哺乳動物細胞におけるラクトジェニック活性の制御
|
|
AU2019241350B2
(en)
|
2018-03-30 |
2025-10-02 |
Nanjing Legend Biotech Co., Ltd. |
Single-domain antibodies against LAG-3 and uses thereof
|
|
WO2019192432A1
(zh)
|
2018-04-02 |
2019-10-10 |
上海博威生物医药有限公司 |
结合淋巴细胞活化基因-3(lag-3)的抗体及其用途
|
|
CN112469477A
(zh)
|
2018-04-04 |
2021-03-09 |
Xencor股份有限公司 |
与成纤维细胞活化蛋白结合的异源二聚体抗体
|
|
TW202011029A
(zh)
|
2018-04-04 |
2020-03-16 |
美商建南德克公司 |
偵測及定量fgf21之方法
|
|
US12054527B2
(en)
|
2018-04-09 |
2024-08-06 |
Amgen Inc. |
Growth differentiation factor 15 fusion proteins
|
|
TW202010757A
(zh)
|
2018-04-11 |
2020-03-16 |
美商英伊布里克斯公司 |
具有經受限cd3結合的多重特異性多肽構築體以及相關方法及用途
|
|
US20210147547A1
(en)
|
2018-04-13 |
2021-05-20 |
Novartis Ag |
Dosage Regimens For Anti-Pd-L1 Antibodies And Uses Thereof
|
|
CR20200459A
(es)
|
2018-04-13 |
2020-11-11 |
Hoffmann La Roche |
Moléculas de unión a antígeno dirigidas a her2 que comprendan 4-1bbl
|
|
CA3097593A1
(en)
|
2018-04-18 |
2019-10-24 |
Xencor, Inc. |
Pd-1 targeted heterodimeric fusion proteins containing il-15/il-15ra fc-fusion proteins and pd-1 antigen binding domains and uses thereof
|
|
KR20210003814A
(ko)
|
2018-04-18 |
2021-01-12 |
젠코어 인코포레이티드 |
IL-15/IL-15Rα Fc-융합 단백질 및 TIM-3 항원 결합 도메인을 함유하는 TIM-3 표적화 이종이량체 융합 단백질
|
|
WO2019204646A1
(en)
|
2018-04-18 |
2019-10-24 |
Xencor, Inc. |
Lag-3 targeted heterodimeric fusion proteins containing il-15/il-15ra fc-fusion proteins and lag-3 antigen binding domains
|
|
AR114789A1
(es)
|
2018-04-18 |
2020-10-14 |
Hoffmann La Roche |
Anticuerpos anti-hla-g y uso de los mismos
|
|
AR115052A1
(es)
|
2018-04-18 |
2020-11-25 |
Hoffmann La Roche |
Anticuerpos multiespecíficos y utilización de los mismos
|
|
CA3097625A1
(en)
|
2018-04-18 |
2019-10-24 |
Xencor, Inc. |
Il-15/il-15ra heterodimeric fc fusion proteins and uses thereof
|
|
US20210047405A1
(en)
|
2018-04-27 |
2021-02-18 |
Novartis Ag |
Car t cell therapies with enhanced efficacy
|
|
MX2020011552A
(es)
|
2018-05-03 |
2020-11-24 |
Genmab Bv |
Combinaciones de variantes de anticuerpos y usos de las mismas.
|
|
AU2019262139A1
(en)
|
2018-05-03 |
2020-11-26 |
Acceleron Pharma Inc. |
Multispecific binders of TGFβ-superfamily ligands and uses thereof
|
|
WO2019219721A1
(en)
|
2018-05-18 |
2019-11-21 |
F. Hoffmann-La Roche Ag |
Targeted intracellular delivery of large nucleic acids
|
|
CN112384534A
(zh)
|
2018-05-21 |
2021-02-19 |
指南针制药有限责任公司 |
用于增强nk细胞对靶细胞的杀死的组合物和方法
|
|
WO2019226658A1
(en)
|
2018-05-21 |
2019-11-28 |
Compass Therapeutics Llc |
Multispecific antigen-binding compositions and methods of use
|
|
US20210213063A1
(en)
|
2018-05-25 |
2021-07-15 |
Novartis Ag |
Combination therapy with chimeric antigen receptor (car) therapies
|
|
CR20200566A
(es)
|
2018-05-25 |
2021-02-19 |
Alector Llc |
Anticuerpos anti-sirpa y metodos de utilización de los mismos
|
|
WO2019232244A2
(en)
|
2018-05-31 |
2019-12-05 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
|
PE20210320A1
(es)
|
2018-06-01 |
2021-02-16 |
Novartis Ag |
Moleculas de union contra bcma y usos de las mismas
|
|
TWI920652B
(zh)
|
2018-06-07 |
2026-04-01 |
美商思進公司 |
喜樹鹼結合物
|
|
TWI848953B
(zh)
|
2018-06-09 |
2024-07-21 |
德商百靈佳殷格翰國際股份有限公司 |
針對癌症治療之多特異性結合蛋白
|
|
IL279367B2
(en)
|
2018-06-13 |
2026-05-01 |
Novartis Ag |
BCMA chimeric antigen receptors and their uses
|
|
CN112469440B
(zh)
|
2018-06-18 |
2024-09-06 |
优瑞科生物技术公司 |
靶向前列腺特异性膜抗原(psma)的构建体和其用途
|
|
CA3104295A1
(en)
|
2018-06-19 |
2019-12-26 |
Atarga, Llc |
Antibody molecules to complement component 5 and uses thereof
|
|
JP7513530B2
(ja)
|
2018-06-22 |
2024-07-09 |
ジェンマブ ホールディング ビー.ブイ. |
抗cd37抗体および抗cd20抗体、組成物、ならびにそれらの使用方法
|
|
AU2019293589A1
(en)
|
2018-06-29 |
2021-01-21 |
Alector Llc |
Anti-SIRP-beta1 antibodies and methods of use thereof
|
|
WO2020010250A2
(en)
|
2018-07-03 |
2020-01-09 |
Elstar Therapeutics, Inc. |
Anti-tcr antibody molecules and uses thereof
|
|
TW202035447A
(zh)
|
2018-07-04 |
2020-10-01 |
瑞士商赫孚孟拉羅股份公司 |
新穎雙特異性促效性4-1bb抗原結合分子
|
|
AR116109A1
(es)
|
2018-07-10 |
2021-03-31 |
Novartis Ag |
Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
|
|
MA53123A
(fr)
|
2018-07-13 |
2021-05-19 |
Genmab As |
Thérapie à médiation par trogocytose utilisant des anticorps cd38
|
|
SMT202300110T1
(it)
|
2018-07-13 |
2023-05-12 |
Alector Llc |
Anticorpi anti-sortilina e relativi metodi di uso
|
|
EP3820900A1
(en)
|
2018-07-13 |
2021-05-19 |
Genmab A/S |
Variants of cd38 antibody and uses thereof
|
|
JP7072715B2
(ja)
|
2018-07-20 |
2022-05-20 |
サーフィス オンコロジー インコーポレイテッド |
抗cd112r組成物及び方法
|
|
WO2020023553A1
(en)
|
2018-07-24 |
2020-01-30 |
Inhibrx, Inc. |
Multispecific polypeptide constructs containing a constrained cd3 binding domain and a receptor binding region and methods of using the same
|
|
JP2021531306A
(ja)
|
2018-07-25 |
2021-11-18 |
アドバンスド アクセラレーター アプリケーションズ エスエー |
神経内分泌腫瘍の処置の方法
|
|
US12435137B2
(en)
|
2018-08-03 |
2025-10-07 |
Chugai Seiyaku Kabushiki Kaisha |
Antigen-binding molecule containing two antigen-binding domains that are linked to each other
|
|
EA202091888A1
(ru)
|
2018-08-08 |
2020-10-23 |
Драгонфлай Терапьютикс, Инк. |
Вариабельные домены антител, нацеленные на рецептор nkg2d
|
|
CA3108427A1
(en)
|
2018-08-08 |
2020-02-13 |
Dragonfly Therapeutics, Inc. |
Multi-specific binding proteins that bind bcma, nkg2d and cd16, and methods of use
|
|
CN113164570B
(zh)
|
2018-08-08 |
2024-05-14 |
蜻蜓疗法股份有限公司 |
结合nkg2d、cd16和肿瘤相关抗原的蛋白质
|
|
US12172106B2
(en)
|
2018-08-09 |
2024-12-24 |
Regeneron Pharmaceuticals, Inc. |
Methods for assessing binding affinity of an antibody variant to the neonatal Fc receptor
|
|
MX2021001431A
(es)
|
2018-08-10 |
2021-05-12 |
Chugai Pharmaceutical Co Ltd |
Molecula de union al antigeno anti grupo de diferenciacion 137 (cd137) y su uso.
|
|
TW202021618A
(zh)
|
2018-08-17 |
2020-06-16 |
美商23與我有限公司 |
抗il1rap抗體及其使用方法
|
|
JP7523349B2
(ja)
|
2018-08-29 |
2024-07-26 |
中外製薬株式会社 |
抗体半分子、および抗体半分子のホモ二量体形成を抑制する方法
|
|
GB201814281D0
(en)
|
2018-09-03 |
2018-10-17 |
Femtogenix Ltd |
Cytotoxic agents
|
|
WO2020055832A1
(en)
|
2018-09-10 |
2020-03-19 |
Genentech, Inc. |
Systems and methods for affinity capillary electrophoresis
|
|
WO2020052543A1
(en)
|
2018-09-10 |
2020-03-19 |
Nanjing Legend Biotech Co., Ltd. |
Single-domain antibodies against cd33 and constructs thereof
|
|
CA3111401A1
(en)
|
2018-09-19 |
2020-03-26 |
Genentech, Inc. |
Therapeutic and diagnostic methods for bladder cancer
|
|
EP3856778A1
(en)
|
2018-09-24 |
2021-08-04 |
The Medical College of Wisconsin, Inc. |
System and method for the development of cd30 bispecific antibodies for immunotherapy of cd30+ malignancies
|
|
US11242396B2
(en)
|
2018-10-01 |
2022-02-08 |
Hoffmann-La Roche Inc. |
Bispecific antigen binding molecules comprising anti-FAP clone 212
|
|
CN112654641A
(zh)
|
2018-10-01 |
2021-04-13 |
豪夫迈·罗氏有限公司 |
具有与cd40的三价结合的双特异性抗原结合分子
|
|
KR102884523B1
(ko)
|
2018-10-03 |
2025-11-10 |
젠코어 인코포레이티드 |
IL-12 이종이량체 Fc-융합 단백질
|
|
AU2019354105A1
(en)
|
2018-10-04 |
2021-04-29 |
Genmab Holding B.V. |
Pharmaceutical compositions comprising bispecific anti-CD37 antibodies
|
|
AU2019356573B2
(en)
|
2018-10-11 |
2025-12-18 |
Inhibrx Biosciences, Inc. |
PD-1 single domain antibodies and therapeutic compositions thereof
|
|
CN113166261A
(zh)
|
2018-10-11 |
2021-07-23 |
印希比股份有限公司 |
B7h3单域抗体及其治疗性组合物
|
|
US12590169B2
(en)
|
2018-10-11 |
2026-03-31 |
Inhibrx Biosciences, Inc. |
5T4 single domain antibodies and therapeutic compositions thereof
|
|
JP7611820B2
(ja)
|
2018-10-11 |
2025-01-10 |
インヒブルクス バイオサイエンシズ インコーポレイテッド |
Dll3シングルドメイン抗体およびその治療用組成物
|
|
CA3116188A1
(en)
|
2018-10-12 |
2020-04-16 |
Xencor, Inc. |
Pd-1 targeted il-15/il-15ralpha fc fusion proteins and uses in combination therapies thereof
|
|
EP3867646A1
(en)
|
2018-10-18 |
2021-08-25 |
F. Hoffmann-La Roche AG |
Diagnostic and therapeutic methods for sarcomatoid kidney cancer
|
|
KR20210080460A
(ko)
|
2018-10-23 |
2021-06-30 |
드래곤플라이 쎄라퓨틱스, 인크. |
이종이량체성 Fc-융합된 단백질
|
|
AU2019365238A1
(en)
|
2018-10-24 |
2021-05-13 |
F. Hoffmann-La Roche Ag |
Conjugated chemical inducers of degradation and methods of use
|
|
WO2020092455A2
(en)
|
2018-10-29 |
2020-05-07 |
The Broad Institute, Inc. |
Car t cell transcriptional atlas
|
|
CN119033684A
(zh)
|
2018-10-29 |
2024-11-29 |
豪夫迈·罗氏有限公司 |
抗体制剂
|
|
CN113454111A
(zh)
|
2018-11-06 |
2021-09-28 |
健玛保 |
抗体配制剂
|
|
JP7497351B2
(ja)
|
2018-11-13 |
2024-06-10 |
コンパス セラピューティクス リミテッド ライアビリティ カンパニー |
チェックポイント分子に対する多重特異性結合性構築物およびその使用
|
|
US20230183379A1
(en)
|
2018-11-20 |
2023-06-15 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Bispecific antibody targeting transferrin receptor 1 and soluble antigen
|
|
KR20210099614A
(ko)
|
2018-12-04 |
2021-08-12 |
노파르티스 아게 |
Cd3에 대한 결합 분자 및 이의 용도
|
|
CA3121699A1
(en)
|
2018-12-05 |
2020-06-11 |
Morphosys Ag |
Multispecific antigen-binding molecules
|
|
BR112021010908A2
(pt)
|
2018-12-06 |
2021-08-31 |
Genentech, Inc. |
Método para tratamento de linfoma difuso de grandes células b, kit e imunoconjugado
|
|
EP3894427A1
(en)
|
2018-12-10 |
2021-10-20 |
Genentech, Inc. |
Photocrosslinking peptides for site specific conjugation to fc-containing proteins
|
|
JP7728701B2
(ja)
|
2018-12-17 |
2025-08-25 |
レビトープ リミテッド |
双子型免疫細胞エンゲージャー
|
|
TWI874341B
(zh)
|
2018-12-18 |
2025-03-01 |
美商健生生物科技公司 |
產生異二聚體抗體之方法
|
|
CN113227131B
(zh)
|
2018-12-20 |
2025-03-04 |
豪夫迈·罗氏有限公司 |
经修饰的抗体Fc及其使用方法
|
|
AU2019402189B2
(en)
|
2018-12-20 |
2023-04-13 |
Novartis Ag |
Dosing regimen and pharmaceutical combination comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives
|
|
US20210386763A1
(en)
|
2018-12-20 |
2021-12-16 |
Novartis Ag |
Pharmaceutical combinations
|
|
US11618776B2
(en)
|
2018-12-20 |
2023-04-04 |
Xencor, Inc. |
Targeted heterodimeric Fc fusion proteins containing IL-15/IL-15RA and NKG2D antigen binding domains
|
|
AR117327A1
(es)
|
2018-12-20 |
2021-07-28 |
23Andme Inc |
Anticuerpos anti-cd96 y métodos de uso de estos
|
|
MX2021007589A
(es)
|
2018-12-21 |
2021-12-10 |
23Andme Inc |
Anticuerpos anti il-36 y procedimientos de uso de estos.
|
|
US20200223925A1
(en)
|
2018-12-21 |
2020-07-16 |
Hoffmann-La Roche Inc. |
Tumor-targeted superagonistic cd28 antigen binding molecules
|
|
CR20210326A
(es)
|
2018-12-21 |
2021-09-10 |
Hoffmann La Roche |
Moléculas agonistas de unión al antígeno cd28 que actúan sobre el tumor
|
|
SG11202102859TA
(en)
|
2018-12-21 |
2021-04-29 |
Hoffmann La Roche |
Antibodies binding to cd3
|
|
WO2020136566A1
(en)
|
2018-12-24 |
2020-07-02 |
Sanofi |
Multispecific binding proteins with mutant fab domains
|
|
JP7734075B2
(ja)
|
2018-12-24 |
2025-09-04 |
サノフイ |
疑似fabベースの多重特異性結合タンパク質
|
|
EP3902560A1
(en)
|
2018-12-28 |
2021-11-03 |
F. Hoffmann-La Roche AG |
A peptide-mhc-i-antibody fusion protein for therapeutic use in a patient with amplified immune response
|
|
WO2020141117A1
(en)
|
2018-12-30 |
2020-07-09 |
F. Hoffmann-La Roche Ag |
Ph-gradient spr-based binding assay
|
|
CA3124352A1
(en)
|
2019-01-04 |
2020-07-09 |
Resolve Therapeutics, Llc |
Treatment of sjogren's disease with nuclease fusion proteins
|
|
BR112021013193A2
(pt)
*
|
2019-01-07 |
2021-09-28 |
Shattuck Labs, Inc. |
Proteínas heterodiméricas para modulação de células t gama delta
|
|
TWI852977B
(zh)
|
2019-01-10 |
2024-08-21 |
美商健生生物科技公司 |
前列腺新抗原及其用途
|
|
US12077592B2
(en)
|
2019-01-18 |
2024-09-03 |
Janssen Biotech, Inc. |
GPRC5D chimeric antigen receptors and cells expressing the same
|
|
WO2020153467A1
(ja)
|
2019-01-24 |
2020-07-30 |
中外製薬株式会社 |
新規がん抗原及びそれらの抗原に対する抗体
|
|
GB201901197D0
(en)
|
2019-01-29 |
2019-03-20 |
Femtogenix Ltd |
G-A Crosslinking cytotoxic agents
|
|
CA3123519A1
(en)
|
2019-02-15 |
2020-08-20 |
Novartis Ag |
Substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
US10871640B2
(en)
|
2019-02-15 |
2020-12-22 |
Perkinelmer Cellular Technologies Germany Gmbh |
Methods and systems for automated imaging of three-dimensional objects
|
|
EP3924054B1
(en)
|
2019-02-15 |
2025-04-02 |
Novartis AG |
3-(1-oxo-5-(piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
AU2020226893B2
(en)
|
2019-02-21 |
2025-02-27 |
Marengo Therapeutics, Inc. |
Multifunctional molecules that bind to T cell related cancer cells and uses thereof
|
|
JP7579795B2
(ja)
|
2019-02-21 |
2024-11-08 |
マレンゴ・セラピューティクス,インコーポレーテッド |
NKp30に結合する抗体分子およびその使用
|
|
SG11202109122SA
(en)
|
2019-02-21 |
2021-09-29 |
Marengo Therapeutics Inc |
Anti-tcr antibody molecules and uses thereof
|
|
SG11202109056TA
(en)
|
2019-02-21 |
2021-09-29 |
Marengo Therapeutics Inc |
Multifunctional molecules that bind to calreticulin and uses thereof
|
|
WO2020172598A1
(en)
|
2019-02-21 |
2020-08-27 |
Elstar Therapeutics, Inc. |
Multifunctional molecules that bind to t cells and uses thereof to treat autoimmune disorders
|
|
EP3927371A1
(en)
|
2019-02-22 |
2021-12-29 |
Novartis AG |
Combination therapies of egfrviii chimeric antigen receptors and pd-1 inhibitors
|
|
MX2021010265A
(es)
|
2019-02-26 |
2021-09-23 |
Janssen Biotech Inc |
Terapias de combinacion y estratificacion de pacientes con anticuerpos anti-egfr/c-met biespecificos.
|
|
EP3930850A1
(en)
|
2019-03-01 |
2022-01-05 |
Xencor, Inc. |
Heterodimeric antibodies that bind enpp3 and cd3
|
|
US20220235144A1
(en)
|
2019-03-04 |
2022-07-28 |
Qilu Puget Sound Biotherapeutics Corporation |
Anti-sirp-alpha antibodies
|
|
BR112021017144A2
(pt)
|
2019-03-08 |
2021-11-09 |
Genentech Inc |
Ensaio para detectar uma proteína associada à membrana, métodos para quantificar a concentração de proteína circulante, para determinar se um paciente com linfoma de células b tem probabilidade de exibir uma resposta a uma terapia anti-cd20, para determinar a afinidade de um anticorpo anti-cd20, para determinar a ativação de células t e método de tratamento de um tumor
|
|
MA55296A
(fr)
|
2019-03-14 |
2022-03-23 |
Hoffmann La Roche |
Traitement du cancer avec des anticorps bispécifiques de her2xcd3 en combinaison avec un mab anti-her2
|
|
JP2022525275A
(ja)
|
2019-03-28 |
2022-05-12 |
エービー ストゥーディオ インコーポレイテッド |
ヘテロ多量体タンパク質及びその使用法
|
|
PH12021552414A1
(en)
|
2019-03-29 |
2022-07-25 |
Atarga Llc |
Anti fgf23 antibody
|
|
WO2020200944A1
(en)
|
2019-03-29 |
2020-10-08 |
F. Hoffmann-La Roche Ag |
Method for generating avid-binding multispecific antibodies
|
|
CN113646622B
(zh)
|
2019-03-29 |
2024-11-12 |
豪夫迈·罗氏有限公司 |
用于多价分子的功能分析的基于spr的结合测定
|
|
CN113677403B
(zh)
|
2019-04-12 |
2024-12-27 |
豪夫迈·罗氏有限公司 |
包含脂质运载蛋白突变蛋白的双特异性抗原结合分子
|
|
KR20220002967A
(ko)
|
2019-04-19 |
2022-01-07 |
제넨테크, 인크. |
항 mertk 항체 및 이의 사용 방법
|
|
AU2020263910A1
(en)
|
2019-04-25 |
2021-10-21 |
F. Hoffmann-La Roche Ag |
Activatable therapeutic multispecific polypeptides with extended half-life
|
|
EP3959237A1
(en)
|
2019-04-25 |
2022-03-02 |
F. Hoffmann-La Roche AG |
Therapeutic multispecific polypeptides activated by polypeptide chain exchange
|
|
JP7812230B2
(ja)
|
2019-04-25 |
2026-02-09 |
エフ. ホフマン-ラ ロシュ アーゲー |
ポリペプチド鎖交換による抗体由来ポリペプチドの生成
|
|
AU2020268896B2
(en)
|
2019-05-03 |
2024-11-28 |
F. Hoffmann-La Roche Ag |
Methods of reducing the enzymatic hydrolysis activity rate in a composition obtained from a purification platform
|
|
KR20220005568A
(ko)
|
2019-05-09 |
2022-01-13 |
제넨테크, 인크. |
항체의 제조 방법
|
|
US20220315661A1
(en)
|
2019-05-09 |
2022-10-06 |
Genmab B.V. |
Dosage regimens for a combination of anti-dr5 antibodies for use in treating cancer
|
|
EP3969907B1
(en)
|
2019-05-13 |
2025-09-24 |
F. Hoffmann-La Roche AG |
Interference-suppressed pharmacokinetic immunoassay
|
|
BR112021022815A2
(pt)
|
2019-05-14 |
2021-12-28 |
Genentech Inc |
Métodos para tratar linfoma folicular, kits, imunoconjugados e polatuzumabe vedotina
|
|
CA3137649A1
(en)
|
2019-05-15 |
2020-11-19 |
Chugai Seiyaku Kabushiki Kaisha |
An antigen-binding molecule, a pharmaceutical composition, and a method
|
|
UY38701A
(es)
|
2019-05-21 |
2020-12-31 |
Novartis Ag |
Moléculas de unión a cd19, conjugados, composiciones que las comprenden y usos de las mismas
|
|
AU2020279224B2
(en)
|
2019-05-21 |
2024-12-05 |
Novartis Ag |
Trispecific binding molecules against BCMA and uses thereof
|
|
US12037378B2
(en)
|
2019-05-21 |
2024-07-16 |
Novartis Ag |
Variant CD58 domains and uses thereof
|
|
WO2020243021A2
(en)
|
2019-05-24 |
2020-12-03 |
Foundation Medicine, Inc. |
Ntrk fusion molecules and uses thereof
|
|
CA3141130A1
(en)
|
2019-05-31 |
2020-12-03 |
ALX Oncology Inc. |
Methods of treating cancer with sirp alpha fc fusion in combination with an immune checkpoint inhibitor
|
|
JP7082245B2
(ja)
|
2019-06-10 |
2022-06-07 |
中外製薬株式会社 |
サイトカイン阻害剤と組み合わせて使用するための抗t細胞抗原結合分子
|
|
TWI877170B
(zh)
|
2019-06-11 |
2025-03-21 |
美商阿列克特有限責任公司 |
抗揀選蛋白抗體之使用方法
|
|
KR20220024637A
(ko)
|
2019-06-19 |
2022-03-03 |
에프. 호프만-라 로슈 아게 |
정의된 조직의 다수 발현 카세트들의 표적화 통합에 의한 3가 항체 발현 세포의 생성 방법
|
|
CA3140297A1
(en)
|
2019-06-19 |
2020-12-24 |
Simon Auslaender |
Method for the generation of a protein expressing cell by targeted integration using cre mrna
|
|
AU2020294879A1
(en)
|
2019-06-19 |
2021-12-16 |
F. Hoffmann-La Roche Ag |
Method for the generation of a bivalent, bispecific antibody expressing cell by targeted integration of multiple expression cassettes in a defined organization
|
|
WO2020254351A1
(en)
|
2019-06-19 |
2020-12-24 |
F. Hoffmann-La Roche Ag |
Method for the generation of a multivalent, multispecific antibody expressing cell by targeted integration of multiple expression cassettes in a defined organization
|
|
AU2020297940A1
(en)
|
2019-06-19 |
2021-12-16 |
F. Hoffmann-La Roche Ag |
Method for the generation of a multivalent, bispecific antibody expressing cell by targeted integration of multiple expression cassettes in a defined organization
|
|
BR112021026293A2
(pt)
|
2019-06-26 |
2022-03-03 |
Hoffmann La Roche |
Moléculas de ligação, anticorpos humanizados, ácido nucleico isolado, célula hospedeira, métodos para produzir a molécula de ligação ao antígeno, para tratar um indivíduo e suprarregular ou prolongar a atividade de células t citotóxicas, composição farmacêutica e uso da molécula
|
|
MX2021015823A
(es)
|
2019-06-26 |
2022-02-03 |
Hoffmann La Roche |
Lineas celulares de mamifero con inactivacion del gen sirtuina-1 (sirt-1).
|
|
EP3990492A1
(en)
|
2019-06-27 |
2022-05-04 |
F. Hoffmann-La Roche AG |
Novel icos antibodies and tumor-targeted antigen binding molecules comprising them
|
|
WO2020264384A1
(en)
|
2019-06-28 |
2020-12-30 |
Amgen Inc. |
Anti-cgrp receptor/anti-pac1 receptor bispecific antigen binding proteins
|
|
JP2022538139A
(ja)
|
2019-07-02 |
2022-08-31 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
変異体インターロイキン-2及び抗cd8抗体を含む免疫複合体
|
|
JP7359864B2
(ja)
|
2019-07-10 |
2023-10-11 |
中外製薬株式会社 |
クローディン6結合分子およびその使用
|
|
AR119382A1
(es)
|
2019-07-12 |
2021-12-15 |
Hoffmann La Roche |
Anticuerpos de pre-direccionamiento y métodos de uso
|
|
AR119393A1
(es)
|
2019-07-15 |
2021-12-15 |
Hoffmann La Roche |
Anticuerpos que se unen a nkg2d
|
|
CA3313684A1
(en)
|
2019-07-16 |
2026-06-21 |
Sanofi |
Neutralizing anti-amyloid beta antibodies for the treatment of alzheimer's disease
|
|
WO2021018925A1
(en)
|
2019-07-31 |
2021-02-04 |
F. Hoffmann-La Roche Ag |
Antibodies binding to gprc5d
|
|
PH12022550239A1
(en)
|
2019-07-31 |
2022-12-19 |
Alector Llc |
Anti-ms4a4a antibodies and methods of use thereof
|
|
JP2022543553A
(ja)
|
2019-07-31 |
2022-10-13 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
Gprc5dに結合する抗体
|
|
TWI832183B
(zh)
|
2019-08-06 |
2024-02-11 |
香港商新旭生技股份有限公司 |
結合至病理性tau種類之抗體及其用途
|
|
CN114585651A
(zh)
|
2019-08-08 |
2022-06-03 |
再生元制药公司 |
新型抗原结合分子形式
|
|
CN114555634B
(zh)
|
2019-08-13 |
2025-01-10 |
美国安进公司 |
用于扩增调节性t细胞的白介素-2突变蛋白
|
|
JP7792330B2
(ja)
|
2019-09-03 |
2025-12-25 |
アムジエン・インコーポレーテツド |
Il-22の経口、直腸内、又は他の消化管関連の組成物及びそれを使用する方法
|
|
ES3064633T3
(en)
|
2019-09-12 |
2026-04-28 |
Hoffmann La Roche |
Compositions and methods of treating lupus nephritis
|
|
AU2020349509A1
(en)
|
2019-09-18 |
2022-03-31 |
Genentech, Inc. |
Anti-KLK7 antibodies, anti-KLK5 antibodies, multispecific anti-KLK5/KLK7 antibodies, and methods of use
|
|
MX2022003266A
(es)
|
2019-09-20 |
2022-04-11 |
Genentech Inc |
Dosis para anticuerpos anti-triptasa.
|
|
US12590171B2
(en)
|
2019-09-27 |
2026-03-31 |
Nanjing GenScript Biotech Co., Ltd. |
Anti-VHH domain antibodies and use thereof
|
|
TWI878355B
(zh)
|
2019-10-02 |
2025-04-01 |
德商百靈佳殷格翰國際股份有限公司 |
用於癌症治療之多重專一性結合蛋白
|
|
ES3061099T3
(en)
|
2019-10-04 |
2026-03-31 |
Amgen Inc |
Use of gdf15 for treating cardiometabolic syndrome and other conditions
|
|
TW202128757A
(zh)
|
2019-10-11 |
2021-08-01 |
美商建南德克公司 |
具有改善之特性的 PD-1 標靶 IL-15/IL-15Rα FC 融合蛋白
|
|
CR20220166A
(es)
|
2019-10-18 |
2022-06-15 |
Genentech Inc |
Métodos para usar inmunoconjugados anti-cd79b para tratar linfoma difuso de linfocitos b grandes
|
|
CN114786679A
(zh)
|
2019-10-21 |
2022-07-22 |
诺华股份有限公司 |
具有维奈托克和tim-3抑制剂的组合疗法
|
|
WO2021079195A1
(en)
|
2019-10-21 |
2021-04-29 |
Novartis Ag |
Tim-3 inhibitors and uses thereof
|
|
AU2020379735A1
(en)
|
2019-11-05 |
2022-05-26 |
Regeneron Pharmaceuticals, Inc. |
N-terminal SCFV multispecific binding molecules
|
|
JP7880817B2
(ja)
|
2019-11-06 |
2026-06-26 |
ジェンマブ ビー.ブイ. |
抗体変種の組み合わせおよびその使用
|
|
CA3160482A1
(en)
*
|
2019-11-08 |
2021-05-14 |
Amgen Inc. |
Engineering charge pair mutations for pairing of hetero-igg molecules
|
|
US20220396839A1
(en)
|
2019-11-12 |
2022-12-15 |
Foundation Medicine, Inc. |
Methods of detecting a fusion gene encoding a neoantigen
|
|
CN114641270A
(zh)
|
2019-11-15 |
2022-06-17 |
豪夫迈·罗氏有限公司 |
防止水性蛋白质溶液中可见颗粒的形成
|
|
MX2022005983A
(es)
|
2019-11-18 |
2022-09-07 |
Janssen Biotech Inc |
Receptores del antígeno quimérico anti-cd79, células car-t, y usos de estos.
|
|
US20230047631A1
(en)
|
2019-11-19 |
2023-02-16 |
Amgen Inc. |
Novel multispecific antibody format
|
|
WO2021108661A2
(en)
|
2019-11-26 |
2021-06-03 |
Novartis Ag |
Chimeric antigen receptors and uses thereof
|
|
WO2021108693A1
(en)
|
2019-11-27 |
2021-06-03 |
ALX Oncology Inc. |
Combination therapies for treating cancer
|
|
CN113135996A
(zh)
|
2019-12-09 |
2021-07-20 |
启愈生物技术(上海)有限公司 |
一种双特异抗体及其应用
|
|
CR20220330A
(es)
|
2019-12-13 |
2022-08-04 |
Genentech Inc |
Anticuerpos anti-ly6g6d y métodos de uso.
|
|
PE20221506A1
(es)
|
2019-12-17 |
2022-10-04 |
Amgen Inc |
Agonista doble de interleucina-2/receptor de tnf para uso en terapia
|
|
JP7369297B2
(ja)
|
2019-12-17 |
2023-10-25 |
ファイザー・インク |
Cd47、pd-l1に特異的な抗体、およびその使用
|
|
BR112022012010A2
(pt)
|
2019-12-18 |
2022-08-30 |
Hoffmann La Roche |
Anticorpos, ácido nucleico isolado, célula hospedeira, formulação farmacêutica, uso do anticorpo, método de produção de um anticorpo, método de tratamento de um indivíduo que tem câncer e método de tratamento de um indivíduo que tem uma doença inflamatória ou autoimune
|
|
CN114828965B
(zh)
|
2019-12-18 |
2025-09-05 |
豪夫迈·罗氏有限公司 |
与hla-a2/mage-a4结合的抗体
|
|
IL293978A
(en)
|
2019-12-20 |
2022-08-01 |
Regeneron Pharma |
New il2 agonists and methods of using them
|
|
US12497434B2
(en)
|
2019-12-20 |
2025-12-16 |
Hoffmann-La Roche Inc. |
IL-37 fusion proteins and uses thereof
|
|
US20230057071A1
(en)
|
2019-12-20 |
2023-02-23 |
Novartis Ag |
Combination of anti tim-3 antibody mbg453 and anti tgf-beta antibody nis793, with or without decitabine or the anti pd-1 antibody spartalizumab, for treating myelofibrosis and myelodysplastic syndrome
|
|
CN115515678A
(zh)
|
2019-12-23 |
2022-12-23 |
基因泰克公司 |
载脂蛋白l1特异性抗体及其使用方法
|
|
MY202559A
(en)
|
2019-12-27 |
2024-05-08 |
Chugai Pharmaceutical Co Ltd |
Anti-ctla-4 antibody and use thereof
|
|
EP4085251B1
(en)
|
2020-01-02 |
2024-07-31 |
F. Hoffmann-La Roche AG |
Method for determining the amount of a therapeutic antibody in the brain
|
|
WO2021138474A2
(en)
|
2020-01-03 |
2021-07-08 |
Marengo Therapeutics, Inc. |
Anti-tcr antibody molecules and uses thereof
|
|
EP4084821A4
(en)
|
2020-01-03 |
2024-04-24 |
Marengo Therapeutics, Inc. |
Multifunctional molecules that bind to cd33 and uses thereof
|
|
JP7675083B2
(ja)
|
2020-01-09 |
2025-05-12 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
新規4-1bbl三量体含有抗原結合分子
|
|
CN110818795B
(zh)
|
2020-01-10 |
2020-04-24 |
上海复宏汉霖生物技术股份有限公司 |
抗tigit抗体和使用方法
|
|
AU2021208515A1
(en)
|
2020-01-15 |
2022-08-04 |
F. Hoffmann-La Roche Ag |
Methods to decrease impurities from recombinant protein manufacturing processes
|
|
MX2022008050A
(es)
|
2020-01-16 |
2022-07-27 |
Genmab As |
Formulaciones de anticuerpos anti cumulo de diferenciacion 38 (cd38) y usos de las mismas.
|
|
EP4090335A1
(en)
|
2020-01-17 |
2022-11-23 |
Novartis AG |
Combination comprising a tim-3 inhibitor and a hypomethylating agent for use in treating myelodysplastic syndrome or chronic myelomonocytic leukemia
|
|
CN115298322A
(zh)
|
2020-01-17 |
2022-11-04 |
贝克顿迪金森公司 |
用于单细胞分泌组学的方法和组合物
|
|
EP4097129A1
(en)
|
2020-01-29 |
2022-12-07 |
Inhibrx, Inc. |
Cd28 single domain antibodies and multivalent and multispecific constructs thereof
|
|
WO2021155916A1
(en)
|
2020-02-04 |
2021-08-12 |
BioNTech SE |
Treatment involving antigen vaccination and binding agents binding to pd-l1 and cd137
|
|
US20230312704A1
(en)
|
2020-02-10 |
2023-10-05 |
Shanghai Escugen Biotechnology Co., Ltd. |
Cldn18.2 antibody and use thereof
|
|
AU2021218927B2
(en)
|
2020-02-10 |
2024-12-19 |
Shanghai Escugen Biotechnology Co., Ltd. |
Claudin 18.2 antibody and use thereof
|
|
IL295382B1
(en)
|
2020-02-12 |
2026-08-01 |
Chugai Seiyaku Kk |
Anti-CD137 antigen-binding molecule for use in cancer treatment
|
|
WO2021173844A1
(en)
|
2020-02-26 |
2021-09-02 |
Biograph 55, Inc. |
C19 c38 bispecific antibodies
|
|
IL295878A
(en)
|
2020-02-27 |
2022-10-01 |
Novartis Ag |
Methods for producing cells expressing a chimeric antigen receptor
|
|
EP4118114A1
(en)
|
2020-03-13 |
2023-01-18 |
Genentech, Inc. |
Anti-interleukin-33 antibodies and uses thereof
|
|
KR20220154757A
(ko)
|
2020-03-18 |
2022-11-22 |
젠맵 에이/에스 |
B7h4에 결합하는 항체
|
|
CA3169626A1
(en)
|
2020-03-19 |
2021-09-23 |
Genentech, Inc. |
Isoform-selective anti-tgf-beta antibodies and methods of use
|
|
CA3169967A1
(en)
|
2020-03-24 |
2021-09-30 |
Genentech, Inc. |
Tie2-binding agents and methods of use
|
|
JP7664943B2
(ja)
|
2020-03-25 |
2025-04-18 |
イーライ リリー アンド カンパニー |
多重特異性結合タンパク質およびそれを開発する方法
|
|
US12098365B2
(en)
|
2020-03-26 |
2024-09-24 |
Genentech, Inc. |
Modified mammalian cells
|
|
WO2021195513A1
(en)
|
2020-03-27 |
2021-09-30 |
Novartis Ag |
Bispecific combination therapy for treating proliferative diseases and autoimmune disorders
|
|
CA3175577A1
(en)
|
2020-03-30 |
2021-10-07 |
Mie University |
Bispecific antibody
|
|
AR121706A1
(es)
|
2020-04-01 |
2022-06-29 |
Hoffmann La Roche |
Moléculas de unión a antígeno biespecíficas dirigidas a ox40 y fap
|
|
US20240183826A9
(en)
|
2020-04-02 |
2024-06-06 |
Chugai Seiyaku Kabushiki Kaisha |
Analysis method for impurity molecules in composition containing multi-specific antigen-binding molecules
|
|
CN115698717A
(zh)
|
2020-04-03 |
2023-02-03 |
基因泰克公司 |
癌症的治疗和诊断方法
|
|
CA3180222A1
(en)
|
2020-04-15 |
2021-10-21 |
Voyager Therapeutics, Inc. |
Tau binding compounds
|
|
CA3168460A1
(en)
|
2020-04-15 |
2021-10-21 |
F. Hoffmann-La Roche Ag |
Immunoconjugates
|
|
MX2022013173A
(es)
|
2020-04-24 |
2022-11-30 |
Hoffmann La Roche |
Modulacion de enzimas y vias con compuestos de sulfhidrilo y sus derivados.
|
|
AU2021261420A1
(en)
|
2020-04-24 |
2022-12-01 |
Marengo Therapeutics, Inc. |
Multifunctional molecules that bind to T cell related cancer cells and uses thereof
|
|
MX2022013198A
(es)
|
2020-04-24 |
2022-11-14 |
Genentech Inc |
Metodos de uso de inmunoconjugados anti-cd79b.
|
|
EP4143345A1
(en)
|
2020-04-28 |
2023-03-08 |
Genentech, Inc. |
Methods and compositions for non-small cell lung cancer immunotherapy
|
|
AU2021263408A1
(en)
|
2020-04-30 |
2022-10-27 |
Bristol-Myers Squibb Company |
Methods of treating cytokine-related adverse events
|
|
US20230242647A1
(en)
|
2020-05-01 |
2023-08-03 |
Novartis Ag |
Engineered immunoglobulins
|
|
JP2023527962A
(ja)
|
2020-05-03 |
2023-07-03 |
レヴィーナ (スジョウ) バイオファーマ カンパニー, リミテッド |
抗trop2抗体を含む抗体薬物複合体(adc)、かかるadcを含む組成物、ならびにそれらを作製および使用する方法
|
|
AU2021268340A1
(en)
|
2020-05-06 |
2022-12-08 |
Dragonfly Therapeutics, Inc. |
Proteins binding NKG2D, CD16 and CLEC12A
|
|
KR20230008775A
(ko)
|
2020-05-08 |
2023-01-16 |
젠맵 에이/에스 |
Cd3 및 cd20에 대한 이중특이적 항체
|
|
US20230181712A1
(en)
|
2020-05-11 |
2023-06-15 |
Hoffmann-La Roche Inc. |
Combination therapy with modified pbmcs and an immunoconjugate
|
|
KR20230009430A
(ko)
|
2020-05-12 |
2023-01-17 |
리제너론 파아마슈티컬스, 인크. |
신규 il10 효능제 및 그의 사용 방법
|
|
WO2021231976A1
(en)
|
2020-05-14 |
2021-11-18 |
Xencor, Inc. |
Heterodimeric antibodies that bind prostate specific membrane antigen (psma) and cd3
|
|
EP4149632A1
(en)
|
2020-05-14 |
2023-03-22 |
Xencor, Inc. |
Heterodimeric antibodies that bind msln and cd3
|
|
CN115605184A
(zh)
|
2020-05-15 |
2023-01-13 |
豪夫迈·罗氏有限公司(Ch) |
防止胃肠外蛋白质溶液中的可见颗粒形成
|
|
CA3179066A1
(en)
|
2020-05-18 |
2021-11-25 |
Jing DENG |
Human il-15 mutant and use thereof
|
|
JP2023525898A
(ja)
|
2020-05-19 |
2023-06-19 |
エフ. ホフマン-ラ ロシュ アーゲー |
非経口タンパク質溶液における可視粒子の形成を防止するためのキレート剤の使用
|
|
JP2023504675A
(ja)
|
2020-05-19 |
2023-02-06 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
ガンの処置のための結合分子
|
|
PE20230460A1
(es)
|
2020-05-29 |
2023-03-10 |
23Andme Inc |
Anticuerpos anti-cd200r1 y metodos de uso de estos
|
|
CA3184495A1
(en)
|
2020-06-08 |
2021-12-16 |
F. Hoffmann-La Roche Ag |
Anti-hbv antibodies and methods of use
|
|
JP2023529206A
(ja)
|
2020-06-12 |
2023-07-07 |
ジェネンテック, インコーポレイテッド |
がん免疫療法のための方法及び組成物
|
|
CA3176552A1
(en)
|
2020-06-19 |
2021-12-23 |
F. Hoffmann-La Roche Ag |
Immune activating fc domain binding molecules
|
|
TW202214704A
(zh)
|
2020-06-19 |
2022-04-16 |
瑞士商赫孚孟拉羅股份公司 |
蛋白酶活化t細胞雙特異性抗體
|
|
WO2021255146A1
(en)
|
2020-06-19 |
2021-12-23 |
F. Hoffmann-La Roche Ag |
Antibodies binding to cd3 and cea
|
|
AR122656A1
(es)
|
2020-06-19 |
2022-09-28 |
Hoffmann La Roche |
Anticuerpos que se unen a cd3 / folr1
|
|
BR112022025536A2
(pt)
|
2020-06-19 |
2023-01-17 |
Chugai Pharmaceutical Co Ltd |
Molécula de ligação ao antígeno de células anti-t para uso em combinação com o inibidor da angiogênese
|
|
IL296089A
(en)
|
2020-06-19 |
2022-11-01 |
Hoffmann La Roche |
Antibodies bind to cd3
|
|
CR20220637A
(es)
|
2020-06-19 |
2023-01-31 |
Hoffmann La Roche |
Anticuerpos que se unen a cd3 y cd19
|
|
US20230235040A1
(en)
|
2020-06-22 |
2023-07-27 |
Almirall, S.A. |
Anti-il-36 antibodies and methods of use thereof
|
|
CR20220627A
(es)
|
2020-06-23 |
2023-02-17 |
Hoffmann La Roche |
Moléculas agonistas de unión al antígeno cd28 que se derigen a her2
|
|
EP4168007A1
(en)
|
2020-06-23 |
2023-04-26 |
Novartis AG |
Dosing regimen comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives
|
|
EP4172192A1
(en)
|
2020-06-24 |
2023-05-03 |
Genentech, Inc. |
Apoptosis resistant cell lines
|
|
CN115916830A
(zh)
|
2020-06-25 |
2023-04-04 |
豪夫迈·罗氏有限公司 |
抗cd3/抗cd28双特异性抗原结合分子
|
|
US20230355722A1
(en)
|
2020-06-29 |
2023-11-09 |
Resolve Therapeutics, Llc |
Treatment of sjogren’s syndrome with nuclease fusion proteins
|
|
WO2022009049A1
(en)
|
2020-07-06 |
2022-01-13 |
Janssen Biotech, Inc. |
Prostate neoantigens and their uses
|
|
EP4175664A2
(en)
|
2020-07-06 |
2023-05-10 |
Janssen Biotech, Inc. |
Prostate neoantigens and their uses
|
|
EP4178529A1
(en)
|
2020-07-07 |
2023-05-17 |
F. Hoffmann-La Roche AG |
Alternative surfactants as stabilizers for therapeutic protein formulations
|
|
WO2022008688A1
(en)
|
2020-07-10 |
2022-01-13 |
F. Hoffmann-La Roche Ag |
Antibodies which bind to cancer cells and target radionuclides to said cells
|
|
CA3176556A1
(en)
|
2020-07-16 |
2022-01-20 |
Novartis Ag |
Anti-betacellulin antibodies, fragments thereof, and multi-specific binding molecules
|
|
CA3185122A1
(en)
|
2020-07-17 |
2022-01-20 |
Cecilia Pui Chi Chiu |
Anti-notch2 antibodies and methods of use
|
|
CA3188656A1
(en)
|
2020-07-17 |
2022-01-20 |
Simurx, Inc. |
Chimeric myd88 receptors for redirecting immunosuppressive signaling and related compositions and methods
|
|
IL299860A
(en)
|
2020-07-21 |
2023-03-01 |
Genentech Inc |
Antibody-conjugated chemical factors for the discharge of BRM and their methods
|
|
US20230293680A1
(en)
|
2020-07-23 |
2023-09-21 |
Genmab B.V. |
A composition of anti-dr5 antibodies and an immunomodulatory imide drug for use in treating multiple myeloma
|
|
GB2597532A
(en)
|
2020-07-28 |
2022-02-02 |
Femtogenix Ltd |
Cytotoxic compounds
|
|
WO2022026592A2
(en)
|
2020-07-28 |
2022-02-03 |
Celltas Bio, Inc. |
Antibody molecules to coronavirus and uses thereof
|
|
TW202220677A
(zh)
|
2020-07-31 |
2022-06-01 |
日商中外製藥股份有限公司 |
含有表現嵌合受體之細胞的醫藥組成物
|
|
EP4188549A1
(en)
|
2020-08-03 |
2023-06-07 |
Novartis AG |
Heteroaryl substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
WO2022029011A1
(en)
|
2020-08-06 |
2022-02-10 |
BioNTech SE |
Binding agents for coronavirus s protein
|
|
US11919958B2
(en)
|
2020-08-19 |
2024-03-05 |
Xencor, Inc. |
Anti-CD28 compositions
|
|
JP2023539645A
(ja)
|
2020-08-26 |
2023-09-15 |
マレンゴ・セラピューティクス,インコーポレーテッド |
Nkp30に結合する抗体分子およびその使用
|
|
AU2021331075A1
(en)
|
2020-08-26 |
2023-04-06 |
Marengo Therapeutics, Inc. |
Multifunctional molecules that bind to calreticulin and uses thereof
|
|
CA3190573A1
(en)
|
2020-08-26 |
2022-03-03 |
Andreas Loew |
Methods of detecting trbc1 or trbc2
|
|
US20230416371A1
(en)
|
2020-08-28 |
2023-12-28 |
Chugai Seiyaku Kabushiki Kaisha |
Heterodimer fc polypeptide
|
|
JP2023539201A
(ja)
|
2020-08-28 |
2023-09-13 |
ジェネンテック, インコーポレイテッド |
宿主細胞タンパク質のCRISPR/Cas9マルチプレックスノックアウト
|
|
WO2022043558A1
(en)
|
2020-08-31 |
2022-03-03 |
Advanced Accelerator Applications International Sa |
Method of treating psma-expressing cancers
|
|
US20230321285A1
(en)
|
2020-08-31 |
2023-10-12 |
Advanced Accelerator Applications International Sa |
Method of treating psma-expressing cancers
|
|
JP2023539525A
(ja)
|
2020-09-02 |
2023-09-14 |
ジェンマブ エー/エス |
抗体療法
|
|
WO2022053654A1
(en)
|
2020-09-10 |
2022-03-17 |
Genmab A/S |
Bispecific antibody against cd3 and cd20 in combination therapy for treating diffuse large b-cell lymphoma
|
|
BR112023004319A2
(pt)
|
2020-09-10 |
2023-04-04 |
Genmab As |
Método para tratar linfoma difuso de grandes células b
|
|
IL301086A
(en)
|
2020-09-10 |
2023-05-01 |
Genmab As |
Bispecific antibody against cd3 and cd20 in combination therapy for treating follicular lymphoma
|
|
JP2023542290A
(ja)
|
2020-09-10 |
2023-10-06 |
ジェンマブ エー/エス |
濾胞性リンパ腫を治療するための併用療法におけるcd3及びcd20に対する二重特異性抗体
|
|
WO2022053657A1
(en)
|
2020-09-10 |
2022-03-17 |
Genmab A/S |
Bispecific antibody against cd3 and cd20 in combination therapy for treating diffuse large b-cell lymphoma
|
|
CN116437956A
(zh)
|
2020-09-10 |
2023-07-14 |
健玛保 |
用于治疗慢性淋巴细胞白血病的针对cd3和cd20的双特异性抗体
|
|
PE20231575A1
(es)
|
2020-09-14 |
2023-10-04 |
Ichnos Sciences SA |
Anticuerpos que se unen a il1rap y usos de estos
|
|
WO2022061214A1
(en)
|
2020-09-21 |
2022-03-24 |
Genentech, Inc. |
Purification of multispecific antibodies
|
|
KR20230068415A
(ko)
|
2020-09-24 |
2023-05-17 |
에프. 호프만-라 로슈 아게 |
유전자 녹아웃을 갖는 포유류 세포주
|
|
EP4674480A3
(en)
|
2020-10-02 |
2026-04-08 |
Keros Therapeutics, Inc. |
Methods of using activin receptor type ii variants
|
|
US20230365714A1
(en)
|
2020-10-02 |
2023-11-16 |
Genmab A/S |
Antibodies capable of binding to ror2 and bispecific antibodies binding to ror2 and cd3
|
|
TW202446417A
(zh)
|
2020-10-05 |
2024-12-01 |
美商建南德克公司 |
用抗 fcrh5/抗 cd3 雙特異性抗體進行治療之給藥
|
|
EP4225786A2
(en)
*
|
2020-10-07 |
2023-08-16 |
Amgen Inc. |
Rational selection of building blocks for the assembly of multispecific antibodies
|
|
KR20230086765A
(ko)
|
2020-10-13 |
2023-06-15 |
얀센 바이오테크 인코포레이티드 |
분화 클러스터 iv 및/또는 viii을 조절하기 위한 바이오-조작된 t 세포 매개 면역, 물질 및 기타 방법
|
|
WO2022082030A2
(en)
|
2020-10-15 |
2022-04-21 |
Gritstone Bio, Inc. |
Antigen-binding proteins and related methods of use
|
|
WO2022086957A1
(en)
|
2020-10-20 |
2022-04-28 |
Genentech, Inc. |
Peg-conjugated anti-mertk antibodies and methods of use
|
|
AU2021363536A1
(en)
|
2020-10-20 |
2023-02-23 |
F. Hoffmann-La Roche Ag |
Combination therapy of PD-1 axis binding antagonists and LRRK2 inhitibors
|
|
TW202233668A
(zh)
|
2020-10-21 |
2022-09-01 |
德商百靈佳殷格翰國際股份有限公司 |
用於治療眼部疾病之雙特異性抗-VEGF及抗-TrkB結合分子
|
|
US12076413B2
(en)
|
2020-10-28 |
2024-09-03 |
Janssen Biotech, Inc. |
Compositions and methods for modulating delta gamma chain mediated immunity
|
|
TWI917473B
(zh)
|
2020-11-02 |
2026-03-11 |
新加坡商蜂鳥生物科技私人有限公司 |
Bcma/taci抗原結合分子
|
|
AU2021373366A1
(en)
|
2020-11-06 |
2023-06-01 |
Novartis Ag |
Cd19 binding molecules and uses thereof
|
|
US20250215081A1
(en)
|
2020-11-06 |
2025-07-03 |
Novartis Ag |
Anti-cd19 agent and b cell targeting agent combination therapy for treating b cell malignancies
|
|
CN117120477A
(zh)
|
2020-11-10 |
2023-11-24 |
上海齐鲁制药研究中心有限公司 |
针对密蛋白18a2和cd3的双特异性抗体及其应用
|
|
KR20230107617A
(ko)
|
2020-11-13 |
2023-07-17 |
노파르티스 아게 |
키메라 항원 수용체(car)-발현 세포를 사용한 병용 요법
|
|
CR20230253A
(es)
|
2020-11-16 |
2023-07-26 |
Hoffmann La Roche |
Glucoformas de fab ricas en manosa
|
|
WO2022101458A1
(en)
|
2020-11-16 |
2022-05-19 |
F. Hoffmann-La Roche Ag |
Combination therapy with fap-targeted cd40 agonists
|
|
JP2023553399A
(ja)
|
2020-12-02 |
2023-12-21 |
アレクトル エルエルシー |
抗ソルチリン抗体の使用法
|
|
CN116723861A
(zh)
|
2020-12-02 |
2023-09-08 |
上海复宏汉霖生物技术股份有限公司 |
抗GARP/TGFβ抗体及使用方法
|
|
KR20230117122A
(ko)
|
2020-12-04 |
2023-08-07 |
에프. 호프만-라 로슈 아게 |
pH 의존성 돌연변이체 인터류킨-2 폴리펩티드
|
|
BR112023008265A2
(pt)
|
2020-12-07 |
2024-02-06 |
UCB Biopharma SRL |
Anticorpos contra interleucina-22
|
|
US20240067758A1
(en)
|
2020-12-07 |
2024-02-29 |
UCB Biopharma SRL |
Multi-specific antibodies and antibody combinations
|
|
WO2022129120A1
(en)
|
2020-12-17 |
2022-06-23 |
F. Hoffmann-La Roche Ag |
Anti-hla-g antibodies and use thereof
|
|
WO2022129313A1
(en)
|
2020-12-18 |
2022-06-23 |
F. Hoffmann-La Roche Ag |
Precursor proteins and kit for targeted therapy
|
|
CN116670282A
(zh)
|
2020-12-22 |
2023-08-29 |
豪夫迈·罗氏有限公司 |
靶向xbp1的寡核苷酸
|
|
EP4740951A3
(en)
|
2020-12-22 |
2026-08-05 |
Foundation Medicine, Inc. |
Igh rearrangements and uses thereof
|
|
CN116829598A
(zh)
|
2021-01-06 |
2023-09-29 |
豪夫迈·罗氏有限公司 |
采用pd1-lag3双特异性抗体和cd20 t细胞双特异性抗体的组合疗法
|
|
WO2022148853A1
(en)
|
2021-01-11 |
2022-07-14 |
F. Hoffmann-La Roche Ag |
Immunoconjugates
|
|
PE20240690A1
(es)
|
2021-01-12 |
2024-04-10 |
Hoffmann La Roche |
Anticuerpos split que se unen a celulas cancerosas y dirigen radionuclidos a dichas celulas
|
|
AU2022207624A1
(en)
|
2021-01-13 |
2023-07-13 |
F. Hoffmann-La Roche Ag |
Combination therapy
|
|
WO2022155503A1
(en)
|
2021-01-14 |
2022-07-21 |
Gritstone Bio, Inc. |
Multi-specific antibodies and methods of use
|
|
WO2022162587A1
(en)
|
2021-01-27 |
2022-08-04 |
Centre Hospitalier Universitaire Vaudois (C.H.U.V.) |
Anti-sars-cov-2 antibodies and use thereof in the treatment of sars-cov-2 infection
|
|
EP4284510A1
(en)
|
2021-01-29 |
2023-12-06 |
Novartis AG |
Dosage regimes for anti-cd73 and anti-entpd2 antibodies and uses thereof
|
|
EP4288458A1
(en)
|
2021-02-03 |
2023-12-13 |
Genentech, Inc. |
Multispecific binding protein degrader platform and methods of use
|
|
AU2022218137A1
(en)
|
2021-02-03 |
2023-08-24 |
Mozart Therapeutics, Inc. |
Binding agents and methods of using the same
|
|
CN117794566A
(zh)
|
2021-02-05 |
2024-03-29 |
Vib研究所 |
沙贝病毒结合剂
|
|
CA3211114A1
(en)
|
2021-02-16 |
2022-08-25 |
Janssen Biotech, Inc. |
Materials and methods for enhanced linker targeting
|
|
WO2022175255A2
(en)
|
2021-02-16 |
2022-08-25 |
Janssen Pharmaceutica Nv |
Trispecific antibody targeting bcma, gprc5d, and cd3
|
|
CN116888473A
(zh)
|
2021-02-18 |
2023-10-13 |
豪夫迈·罗氏有限公司 |
用于解析复杂、多步骤抗体相互作用的方法
|
|
BR112023016706A2
(pt)
|
2021-02-19 |
2023-10-31 |
Seoul Nat Univ R&Db Foundation |
Anticorpo ou um fragmento de ligação ao antígeno do mesmo, molécula de ácido nucleico, métodos para produzir um anticorpo ou um fragmento de ligação ao antígeno do mesmo e para detectar agrupamento de diferenciação 47 ou determinar uma quantidade de agrupamento de diferenciação 47 em uma amostra, e, uso do anticorpo ou de um fragmento de ligação ao antígeno do mesmo
|
|
BR112023016713A2
(pt)
|
2021-02-19 |
2023-10-31 |
Seoul Nat Univ R&Db Foundation |
Anticorpo ou um fragmento de ligação ao antígeno do mesmo, molécula de ácido nucleico, métodos para produzir um anticorpo ou um fragmento de ligação ao antígeno do mesmo e para detectar agrupamento de diferenciação 47 ou determinar uma quantidade de agrupamento de diferenciação 47 em uma amostra, e, uso do anticorpo ou de um fragmento de ligação ao antígeno do mesmo
|
|
WO2022184082A1
(en)
|
2021-03-03 |
2022-09-09 |
Sorrento Therapeutics, Inc. |
Antibody-drug conjugates comprising an anti-bcma antibody
|
|
EP4301774A4
(en)
|
2021-03-03 |
2025-08-13 |
Dragonfly Therapeutics Inc |
METHODS OF TREATING CANCER USING MULTI-SPECIFIC BINDING PROTEINS THAT BIND TO NKG2D, CD16, AND A TUMOR-ASSOCIATED ANTIGEN
|
|
AU2022231874A1
(en)
|
2021-03-09 |
2023-07-27 |
F. Hoffmann-La Roche Ag |
Combination therapy of pd-1-targeted il-2 variant immunoconjugates and fap/4-1bb binding molecules
|
|
CN117015555A
(zh)
|
2021-03-09 |
2023-11-07 |
豪夫迈·罗氏有限公司 |
Pd-1靶向il-2变体免疫缀合物和抗tyrp1/抗cd3双特异性抗体的组合疗法
|
|
EP4305067A1
(en)
|
2021-03-09 |
2024-01-17 |
Xencor, Inc. |
Heterodimeric antibodies that bind cd3 and cldn6
|
|
US11859012B2
(en)
|
2021-03-10 |
2024-01-02 |
Xencor, Inc. |
Heterodimeric antibodies that bind CD3 and GPC3
|
|
KR20230156921A
(ko)
|
2021-03-12 |
2023-11-15 |
젠맵 에이/에스 |
비-활성화 항체 변이체
|
|
EP4304732A1
(en)
|
2021-03-12 |
2024-01-17 |
Genentech, Inc. |
Anti-klk7 antibodies, anti-klk5 antibodies, multispecific anti-klk5/klk7 antibodies, and methods of use
|
|
EP4454652A3
(en)
|
2021-03-15 |
2025-05-21 |
F. Hoffmann-La Roche AG |
Compositions and methods for treating lupus nephritis
|
|
US20240174746A1
(en)
|
2021-03-18 |
2024-05-30 |
Alector Llc |
Anti-tmem106b antibodies and methods of use thereof
|
|
WO2022197877A1
(en)
|
2021-03-19 |
2022-09-22 |
Genentech, Inc. |
Methods and compositions for time delayed bio-orthogonal release of cytotoxic agents
|
|
EP4314063A1
(en)
|
2021-03-23 |
2024-02-07 |
Alector LLC |
Anti-tmem106b antibodies for treating and preventing coronavirus infections
|
|
AR125210A1
(es)
|
2021-03-24 |
2023-06-21 |
Janssen Biotech Inc |
Anticuerpos dirigidos a cd22 y cd79b
|
|
WO2022201122A1
(en)
|
2021-03-26 |
2022-09-29 |
Janssen Biotech, Inc. |
Humanized antibodies against paired helical filament tau and uses thereof
|
|
CN117321087A
(zh)
|
2021-03-26 |
2023-12-29 |
先天制药公司 |
包含与细胞因子融合用于nk细胞衔接的nkp46结合位点、癌抗原结合位点的多特异性蛋白质
|
|
TW202304991A
(zh)
|
2021-03-29 |
2023-02-01 |
日商第一三共股份有限公司 |
穩定的多重特異性分子及其利用
|
|
US20240301031A1
(en)
|
2021-03-31 |
2024-09-12 |
Jiangsu Hengrui Pharmaceuticals Co., Ltd. |
Truncated taci polypeptide and fusion protein and use thereof
|
|
TW202304994A
(zh)
|
2021-04-02 |
2023-02-01 |
美商泰尼歐生物公司 |
促效性抗il-2r抗體及使用方法
|
|
TW202304979A
(zh)
|
2021-04-07 |
2023-02-01 |
瑞士商諾華公司 |
抗TGFβ抗體及其他治療劑用於治療增殖性疾病之用途
|
|
CA3214757A1
(en)
|
2021-04-08 |
2022-10-13 |
Andreas Loew |
Multifuntional molecules binding to tcr and uses thereof
|
|
JP2024513474A
(ja)
|
2021-04-09 |
2024-03-25 |
エフ. ホフマン-ラ ロシュ アーゲー |
異種ポリペプチドを発現する細胞クローンを選択するための方法
|
|
WO2022217022A1
(en)
|
2021-04-10 |
2022-10-13 |
Profoundbio Us Co. |
Folr1 binding agents, conjugates thereof and methods of using the same
|
|
AR125344A1
(es)
|
2021-04-15 |
2023-07-05 |
Chugai Pharmaceutical Co Ltd |
Anticuerpo anti-c1s
|
|
JP2024514222A
(ja)
|
2021-04-19 |
2024-03-28 |
ジェネンテック, インコーポレイテッド |
改変された哺乳動物細胞
|
|
CA3216459A1
(en)
|
2021-04-23 |
2022-10-27 |
Profoundbio Us Co. |
Anti-cd70 antibodies, conjugates thereof and methods of using the same
|
|
WO2022228706A1
(en)
|
2021-04-30 |
2022-11-03 |
F. Hoffmann-La Roche Ag |
Dosing for treatment with anti-cd20/anti-cd3 bispecific antibody
|
|
CA3213632A1
(en)
|
2021-04-30 |
2022-11-03 |
F. Hoffmann-La Roche Ag |
Dosing for combination treatment with anti-cd20/anti-cd3 bispecific antibody and anti-cd79b antibody drug conjugate
|
|
AR125732A1
(es)
|
2021-05-03 |
2023-08-09 |
UCB Biopharma SRL |
Anticuerpos anti-trem1
|
|
CN117597365A
(zh)
|
2021-05-04 |
2024-02-23 |
再生元制药公司 |
多特异性fgf21受体激动剂及其应用
|
|
BR112023022878A2
(pt)
|
2021-05-04 |
2024-01-23 |
Regeneron Pharma |
Agonistas do receptor fgf21 multiespecíficos e seus usos
|
|
KR20240004949A
(ko)
|
2021-05-07 |
2024-01-11 |
젠맵 에이/에스 |
B7h4 및 cd3에 결합하는 이중특이적 항체를 포함하는 제약 조성물
|
|
WO2022238481A1
(en)
|
2021-05-11 |
2022-11-17 |
Modiquest B.V. |
Antibodies
|
|
EP4337266A1
(en)
|
2021-05-12 |
2024-03-20 |
Genentech, Inc. |
Methods of using anti-cd79b immunoconjugates to treat diffuse large b-cell lymphoma
|
|
US20240254245A1
(en)
|
2021-05-12 |
2024-08-01 |
Jiangsu Hengrui Pharmaceuticals Co., Ltd. |
Antigen binding molecule specifically binding to rankl and ngf, and medical use thereof
|
|
JP2024520902A
(ja)
|
2021-05-13 |
2024-05-27 |
エーエルエックス オンコロジー インコーポレイテッド |
がんを治療するための併用療法
|
|
AU2022273737A1
(en)
|
2021-05-14 |
2023-11-16 |
Jiangsu Hengrui Pharmaceuticals Co., Ltd. |
Antigen-binding molecule
|
|
WO2022241082A1
(en)
|
2021-05-14 |
2022-11-17 |
Genentech, Inc. |
Agonists of trem2
|
|
AR125874A1
(es)
|
2021-05-18 |
2023-08-23 |
Novartis Ag |
Terapias de combinación
|
|
WO2022243261A1
(en)
|
2021-05-19 |
2022-11-24 |
F. Hoffmann-La Roche Ag |
Agonistic cd40 antigen binding molecules targeting cea
|
|
CN117396599A
(zh)
|
2021-05-21 |
2024-01-12 |
基因泰克公司 |
用于生产目的重组产物的经修饰的细胞
|
|
CN113278071B
(zh)
|
2021-05-27 |
2021-12-21 |
江苏荃信生物医药股份有限公司 |
抗人干扰素α受体1单克隆抗体及其应用
|
|
AR126009A1
(es)
|
2021-06-02 |
2023-08-30 |
Hoffmann La Roche |
Moléculas agonistas de unión al antígeno cd28 que se dirigen a epcam
|
|
JP2024520261A
(ja)
|
2021-06-04 |
2024-05-24 |
中外製薬株式会社 |
抗ddr2抗体およびその使用
|
|
IL308015A
(en)
|
2021-06-09 |
2023-12-01 |
Hoffmann La Roche |
Combination of a particular braf inhibitor (paradox breaker) and a pd-1 axis binding antagonist for use in the treatment of cancer
|
|
WO2022258678A1
(en)
|
2021-06-09 |
2022-12-15 |
Innate Pharma |
Multispecific proteins binding to nkp30, a cytokine receptor, a tumour antigen and cd16a
|
|
KR20240019786A
(ko)
|
2021-06-09 |
2024-02-14 |
이나뜨 파르마 에스.에이. |
Cd20, nkp46, cd16에 결합하고 il-2에 접합된 다중특이적 항체
|
|
CN117616050A
(zh)
|
2021-06-09 |
2024-02-27 |
先天制药公司 |
与nkp46、细胞因子受体、肿瘤抗原和cd16a结合的多特异性蛋白质
|
|
WO2022258691A1
(en)
|
2021-06-09 |
2022-12-15 |
Innate Pharma |
Multispecific proteins binding to nkg2d, a cytokine receptor, a tumour antigen and cd16a
|
|
CN117642426A
(zh)
|
2021-06-16 |
2024-03-01 |
艾莱克特有限责任公司 |
双特异性抗MerTK和抗PDL1抗体及其使用方法
|
|
WO2022266221A1
(en)
|
2021-06-16 |
2022-12-22 |
Alector Llc |
Monovalent anti-mertk antibodies and methods of use thereof
|
|
EP4355778A1
(en)
|
2021-06-17 |
2024-04-24 |
Boehringer Ingelheim International GmbH |
Novel tri-specific binding molecules
|
|
WO2022263638A1
(en)
|
2021-06-17 |
2022-12-22 |
Centre Hospitalier Universitaire Vaudois (C.H.U.V.) |
Anti-sars-cov-2 antibodies and use thereof in the treatment of sars-cov-2 infection
|
|
JP2024523034A
(ja)
|
2021-06-18 |
2024-06-25 |
エフ. ホフマン-ラ ロシュ アーゲー |
二重特異性抗ccl2抗体
|
|
BR112023027006A2
(pt)
|
2021-06-21 |
2024-03-12 |
BioNTech SE |
Método para reduzir ou prevenir a progressão de um tumor ou tratar um câncer em um sujeito, e, agente de ligação
|
|
WO2022269451A1
(en)
|
2021-06-22 |
2022-12-29 |
Novartis Ag |
Bispecific antibodies for use in treatment of hidradenitis suppurativa
|
|
WO2022272128A1
(en)
|
2021-06-24 |
2022-12-29 |
Erasca, Inc. |
Antibodies against egfr and their uses
|
|
US12448451B2
(en)
|
2021-06-25 |
2025-10-21 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-CTLA-4 antibody and use thereof
|
|
CN117616123B
(zh)
|
2021-06-25 |
2024-11-08 |
中外制药株式会社 |
抗ctla-4抗体
|
|
IL308633B2
(en)
|
2021-06-25 |
2025-12-01 |
Chugai Pharmaceutical Co Ltd |
Use of anti-ctla-4 antibody
|
|
JP2024524378A
(ja)
|
2021-06-29 |
2024-07-05 |
山▲東▼先声生物制▲薬▼有限公司 |
Cd16抗体及びその応用
|
|
KR20240028452A
(ko)
|
2021-07-02 |
2024-03-05 |
제넨테크, 인크. |
암을 치료하기 위한 방법 및 조성물
|
|
TW202320857A
(zh)
|
2021-07-06 |
2023-06-01 |
美商普方生物製藥美國公司 |
連接子、藥物連接子及其結合物及其使用方法
|
|
EP4512826A3
(en)
|
2021-07-09 |
2025-04-02 |
Luxembourg Institute Of Health (LIH) |
Dimeric protein complexes and uses thereof
|
|
WO2023287663A1
(en)
|
2021-07-13 |
2023-01-19 |
Genentech, Inc. |
Multi-variate model for predicting cytokine release syndrome
|
|
EP4372001A4
(en)
|
2021-07-14 |
2025-02-12 |
Jiangsu Hengrui Pharmaceuticals Co., Ltd. |
ANTIGEN-BINDING MOLECULE SPECIFICALLY BINDING TO HGFR AND EGFR, AND PHARMACEUTICAL USE THEREOF
|
|
PE20240638A1
(es)
|
2021-07-14 |
2024-03-27 |
Genentech Inc |
Anticuerpos anti-receptor de quimiocinas de motivo c-c 8 (ccr8) y metodos de uso
|
|
AU2022314734A1
(en)
|
2021-07-19 |
2024-02-08 |
Regeneron Pharmaceuticals, Inc. |
Il12 receptor agonists and methods of use thereof
|
|
JP2024528631A
(ja)
|
2021-07-22 |
2024-07-30 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
ヘテロ二量体Fcドメイン抗体
|
|
JP2024526880A
(ja)
|
2021-07-22 |
2024-07-19 |
ジェネンテック, インコーポレイテッド |
脳標的化組成物及びその使用方法
|
|
WO2023010060A2
(en)
|
2021-07-27 |
2023-02-02 |
Novab, Inc. |
Engineered vlrb antibodies with immune effector functions
|
|
AU2022318255A1
(en)
|
2021-07-27 |
2024-01-18 |
Morphosys Ag |
Combinations of antigen binding molecules
|
|
IL309120A
(en)
|
2021-07-28 |
2024-02-01 |
Hoffmann La Roche |
Methods and compositions for the treatment of cancer
|
|
JP2024528217A
(ja)
|
2021-08-03 |
2024-07-26 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
二重特異性抗体および使用方法
|
|
CN117897409A
(zh)
|
2021-08-13 |
2024-04-16 |
基因泰克公司 |
抗类胰蛋白酶抗体的给药
|
|
CA3229369A1
(en)
|
2021-08-16 |
2023-02-23 |
Regeneron Pharmaceuticals, Inc. |
Novel il27 receptor agonists and methods of use thereof
|
|
JP2024534265A
(ja)
|
2021-08-23 |
2024-09-18 |
イミュニタス セラピューティクス,インコーポレーテッド |
抗cd161抗体及びその使用
|
|
WO2023028591A1
(en)
|
2021-08-27 |
2023-03-02 |
Genentech, Inc. |
Methods of treating tau pathologies
|
|
TW202325727A
(zh)
|
2021-08-30 |
2023-07-01 |
美商建南德克公司 |
抗聚泛素多特異性抗體
|
|
CN113683694B
(zh)
|
2021-09-03 |
2022-05-13 |
江苏荃信生物医药股份有限公司 |
一种抗人tslp单克隆抗体及其应用
|
|
CN113603775B
(zh)
|
2021-09-03 |
2022-05-20 |
江苏荃信生物医药股份有限公司 |
抗人白介素-33单克隆抗体及其应用
|
|
AR127743A1
(es)
|
2021-09-06 |
2024-02-28 |
Genmab Bv |
Anticuerpos capaces de unirse a cd27, variantes y usos de los mismos
|
|
WO2023044483A2
(en)
|
2021-09-20 |
2023-03-23 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of her2 positive cancer
|
|
WO2023046071A1
(zh)
|
2021-09-23 |
2023-03-30 |
江苏恒瑞医药股份有限公司 |
抗klb抗体及用途
|
|
US20240400670A1
(en)
|
2021-09-30 |
2024-12-05 |
Jiangsu Hengrui Pharmaceuticals Co., Ltd. |
Anti-il23 antibody fusion protein and uses thereof
|
|
CN118562018B
(zh)
*
|
2021-09-30 |
2024-12-13 |
宁波三生生物科技股份有限公司 |
重组促卵泡激素融合蛋白
|
|
EP4413998A4
(en)
|
2021-10-08 |
2026-02-25 |
Chugai Pharmaceutical Co Ltd |
METHOD FOR PREPARING A PRE-FILLED SYRINGE FORMULATION
|
|
AR127298A1
(es)
|
2021-10-08 |
2024-01-10 |
Genmab As |
Anticuerpos que se unen a cd30 y cd3
|
|
WO2023064876A1
(en)
|
2021-10-14 |
2023-04-20 |
Teneobio, Inc. |
Mesothelin binding proteins and uses thereof
|
|
PE20241627A1
(es)
|
2021-10-14 |
2024-08-07 |
Hoffmann La Roche |
Nuevos inmunoconjugados de interleucina-7
|
|
EP4429706A1
(en)
|
2021-10-14 |
2024-09-18 |
F. Hoffmann-La Roche AG |
Alternative pd1-il7v immunoconjugates for the treatment of cancer
|
|
CA3234162A1
(en)
|
2021-10-15 |
2023-04-20 |
Michele Fiscella |
Antibodies and methods of using thereof
|
|
IL312221A
(en)
|
2021-10-20 |
2024-06-01 |
Synthekine Inc |
Heterodimeric fc cytokines and uses thereof
|
|
WO2023076876A1
(en)
|
2021-10-26 |
2023-05-04 |
Mozart Therapeutics, Inc. |
Modulation of immune responses to viral vectors
|
|
US20250011428A1
(en)
|
2021-10-28 |
2025-01-09 |
Novartis Ag |
Engineered fc variants
|
|
WO2023086807A1
(en)
|
2021-11-10 |
2023-05-19 |
Genentech, Inc. |
Anti-interleukin-33 antibodies and uses thereof
|
|
US12559576B2
(en)
|
2021-11-11 |
2026-02-24 |
Regeneron Pharmaceuticals, Inc. |
CD20-PD1 binding molecules and methods of use thereof
|
|
WO2023091887A1
(en)
|
2021-11-16 |
2023-05-25 |
Genentech, Inc. |
Methods and compositions for treating systemic lupus erythematosus (sle) with mosunetuzumab
|
|
WO2023092004A1
(en)
|
2021-11-17 |
2023-05-25 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of tau-related disorders
|
|
CN118284809A
(zh)
|
2021-11-25 |
2024-07-02 |
豪夫迈·罗氏有限公司 |
少量抗体副产物的定量
|
|
CN118284625A
(zh)
|
2021-11-26 |
2024-07-02 |
豪夫迈·罗氏有限公司 |
抗tyrp1/抗cd3双特异性抗体与tyrp1特异性抗体的组合疗法
|
|
WO2023100829A1
(ja)
|
2021-11-30 |
2023-06-08 |
第一三共株式会社 |
プロテアーゼ分解性マスク抗体
|
|
KR20240011866A
(ko)
|
2021-12-01 |
2024-01-26 |
추가이 세이야쿠 가부시키가이샤 |
항체 함유 제제의 조제 방법
|
|
EP4428156A4
(en)
|
2021-12-03 |
2026-03-04 |
Shandong Simcere Biopharmaceutical Co., Ltd. |
ANTI-BCMA NANOBODY AND USE THEREOF
|
|
AR127887A1
(es)
|
2021-12-10 |
2024-03-06 |
Hoffmann La Roche |
Anticuerpos que se unen a cd3 y plap
|
|
CN118488965A
(zh)
|
2021-12-17 |
2024-08-13 |
上海复宏汉霖生物技术股份有限公司 |
抗ox40抗体、多特异性抗体及其使用方法
|
|
AU2022411573A1
(en)
|
2021-12-17 |
2024-06-27 |
Shanghai Henlius Biologics Co., Ltd. |
Anti-ox40 antibodies and methods of use
|
|
CR20240246A
(es)
|
2021-12-20 |
2024-07-19 |
Hoffmann La Roche |
Anticuerpos agonistas anti-ltbr y anticuerpos biespecificos que los comprenden
|
|
CN118401674A
(zh)
|
2021-12-21 |
2024-07-26 |
豪夫迈·罗氏有限公司 |
用于确定水解活性的方法
|
|
TW202346346A
(zh)
|
2021-12-23 |
2023-12-01 |
大陸商江蘇恆瑞醫藥股份有限公司 |
抗dll3抗體、其抗體-藥物偶聯物及其醫藥用途
|
|
WO2023125888A1
(zh)
|
2021-12-31 |
2023-07-06 |
山东先声生物制药有限公司 |
一种gprc5d抗体及其应用
|
|
EP4463479A1
(en)
|
2022-01-12 |
2024-11-20 |
Vib Vzw |
Human ntcp binders for therapeutic use and liver-specific targeted delivery
|
|
WO2023141445A1
(en)
|
2022-01-19 |
2023-07-27 |
Genentech, Inc. |
Anti-notch2 antibodies and conjugates and methods of use
|
|
AR128331A1
(es)
|
2022-01-26 |
2024-04-17 |
Genentech Inc |
Inductores químicos de degradación conjugados con anticuerpos y métodos de estos
|
|
AR128330A1
(es)
|
2022-01-26 |
2024-04-17 |
Genentech Inc |
Inductores químicos de degradación conjugados con anticuerpo y métodos de estos
|
|
KR20240144239A
(ko)
|
2022-01-28 |
2024-10-02 |
젠맵 에이/에스 |
미만성 대 b-세포 림프종을 치료하기 위한 조합 요법에서의 cd3 및 cd20에 대한 이중특이적 항체
|
|
CA3243415A1
(en)
|
2022-01-28 |
2023-08-03 |
Genmab A/S |
Bispecific antibodies against CD3 and CD20 in a polytherapy regimen for the treatment of diffuse large B-cell lymphoma
|
|
WO2023147784A1
(zh)
|
2022-02-07 |
2023-08-10 |
江苏恒瑞医药股份有限公司 |
特异性结合psma和cd3的抗原结合分子及其医药用途
|
|
TW202342548A
(zh)
|
2022-02-07 |
2023-11-01 |
美商威特拉公司 |
抗獨特型(anti-idiotype)抗體分子及其用途
|
|
AU2023218678A1
(en)
|
2022-02-09 |
2024-08-01 |
Daiichi Sankyo Company, Limited |
Environmentally responsive masked antibody and use thereof
|
|
EP4477673A4
(en)
|
2022-02-11 |
2025-09-03 |
Jiangsu Hengrui Pharmaceuticals Co Ltd |
IMMUNOCONJUGATE AND ITS USE
|
|
IL315262A
(en)
|
2022-03-03 |
2024-10-01 |
Pfizer |
Multiple specific antibodies related to IL-4, IL-13 and/or TSLP and their uses
|
|
JP2025509286A
(ja)
|
2022-03-10 |
2025-04-11 |
ビバソル, インコーポレイテッド |
抗体-薬物コンジュゲートおよびその使用
|
|
EP4490185A1
(en)
|
2022-03-11 |
2025-01-15 |
JANSSEN Pharmaceutica NV |
Multispecific antibodies and uses thereof
|
|
TW202400636A
(zh)
|
2022-03-11 |
2024-01-01 |
比利時商健生藥品公司 |
多特異性抗體及其用途(一)
|
|
CA3254442A1
(en)
|
2022-03-11 |
2023-09-14 |
Janssen Pharmaceutica Nv |
MULTISPECIFIC ANTIBODIES AND THEIR USES
|
|
MX2024011128A
(es)
|
2022-03-14 |
2024-09-18 |
Jiangsu Hengrui Pharmaceuticals Co Ltd |
Molecula de union a antigeno que se une especificamente a gprc5d y cd3 y su uso medico.
|
|
WO2023174521A1
(en)
|
2022-03-15 |
2023-09-21 |
Genmab A/S |
Binding agents binding to epcam and cd137
|
|
WO2023176881A1
(ja)
|
2022-03-16 |
2023-09-21 |
第一三共株式会社 |
多重特異的分子と免疫チェックポイント阻害剤の組み合わせ
|
|
EP4493593A1
(en)
|
2022-03-18 |
2025-01-22 |
Evolveimmune Therapeutics, Inc. |
Bispecific antibody fusion molecules and methods of use thereof
|
|
US20230414750A1
(en)
|
2022-03-23 |
2023-12-28 |
Hoffmann-La Roche Inc. |
Combination treatment of an anti-cd20/anti-cd3 bispecific antibody and chemotherapy
|
|
KR20240163119A
(ko)
|
2022-03-25 |
2024-11-18 |
상하이 헨리우스 바이오테크, 인크. |
항-msln 항체 및 사용 방법
|
|
AR128876A1
(es)
|
2022-03-28 |
2024-06-19 |
Hoffmann La Roche |
Anticuerpos biespecíficos de linfocitos t activables con proteasa folr1 mejorados
|
|
WO2023191816A1
(en)
|
2022-04-01 |
2023-10-05 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
|
WO2023198839A2
(en)
|
2022-04-13 |
2023-10-19 |
Genmab A/S |
Bispecific antibodies against cd3 and cd20
|
|
TW202545564A
(zh)
|
2022-04-13 |
2025-12-01 |
美商建南德克公司 |
治療性蛋白質之醫藥組成物及使用方法
|
|
WO2023198727A1
(en)
|
2022-04-13 |
2023-10-19 |
F. Hoffmann-La Roche Ag |
Pharmaceutical compositions of anti-cd20/anti-cd3 bispecific antibodies and methods of use
|
|
EP4511388A1
(en)
|
2022-04-19 |
2025-02-26 |
F. Hoffmann-La Roche AG |
Improved production cells
|
|
IL316174A
(en)
|
2022-04-26 |
2024-12-01 |
Novartis Ag |
Multiple specific antibodies targeting IL-13 and IL-18
|
|
KR20250005335A
(ko)
|
2022-04-26 |
2025-01-09 |
추가이 세이야쿠 가부시키가이샤 |
의약 제제 함유 필터 내장 시린지
|
|
PE20242350A1
(es)
|
2022-05-03 |
2024-12-16 |
Genentech Inc |
Anticuerpos anti-ly6e, inmunoconjugados y usos de estos
|
|
JP2025517650A
(ja)
|
2022-05-11 |
2025-06-10 |
ジェネンテック, インコーポレイテッド |
抗FcRH5/抗CD3二重特異性抗体による処置のための投与
|
|
IL316892A
(en)
|
2022-05-11 |
2025-01-01 |
Regeneron Pharma |
Multispecific proprotein binding molecules and their uses
|
|
US20240059799A1
(en)
|
2022-05-11 |
2024-02-22 |
Pfizer Inc. |
Anti-tl1a antibodies and methods of use thereof
|
|
CA3253038A1
(en)
|
2022-05-12 |
2023-11-16 |
Genmab A/S |
LIAISON AGENTS CAPABLE OF BINDING TO CD27 IN POLYTHERAPY
|
|
TW202409090A
(zh)
|
2022-05-12 |
2024-03-01 |
丹麥商珍美寶股份有限公司 |
在組合療法中能夠結合到cd27之結合劑
|
|
WO2023220695A2
(en)
|
2022-05-13 |
2023-11-16 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of her2 positive cancer
|
|
JP2025519158A
(ja)
|
2022-05-27 |
2025-06-24 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
インターロイキン-2プロタンパク質及びその使用
|
|
JP2025517572A
(ja)
|
2022-06-03 |
2025-06-05 |
エフ. ホフマン-ラ ロシュ アーゲー |
改良された産生細胞
|
|
CN119654338A
(zh)
|
2022-06-04 |
2025-03-18 |
再生元制药公司 |
白细胞介素-2蛋白质原及其用途
|
|
WO2023236889A1
(zh)
|
2022-06-06 |
2023-12-14 |
山东先声生物制药有限公司 |
靶向bcma、gprc5d和t细胞的多特异性抗体及其应用
|
|
KR20250027562A
(ko)
|
2022-06-23 |
2025-02-26 |
지앙수 헨그루이 파마슈티컬스 컴퍼니 리미티드 |
Dll3 및 cd3에 특이적으로 결합하는 항원 결합 분자 및 이의 의약적 용도
|
|
CN119585308A
(zh)
|
2022-07-13 |
2025-03-07 |
基因泰克公司 |
针对用抗fcrh5/抗cd3双特异性抗体进行的治疗的给药
|
|
WO2024013315A1
(en)
|
2022-07-15 |
2024-01-18 |
Boehringer Ingelheim International Gmbh |
Binding molecules for the treatment of cancer
|
|
KR20250040020A
(ko)
|
2022-07-19 |
2025-03-21 |
제넨테크, 인크. |
항-fcrh5/항-cd3 이중특이성 항체로 치료하기 위한 투약법
|
|
EP4558529A1
(en)
|
2022-07-22 |
2025-05-28 |
Bristol-Myers Squibb Company |
Antibodies binding to human pad4 and uses thereof
|
|
CN119654349A
(zh)
|
2022-07-22 |
2025-03-18 |
基因泰克公司 |
抗steap1抗原结合分子及其用途
|
|
EP4561613A1
(en)
|
2022-07-27 |
2025-06-04 |
Teneobio, Inc. |
Mesothelin binding proteins and uses thereof
|
|
CN119497721A
(zh)
|
2022-07-29 |
2025-02-21 |
艾莱克特有限责任公司 |
转铁蛋白受体抗原结合结构域及其用途
|
|
MA71622A
(fr)
|
2022-07-29 |
2025-05-30 |
Alector Llc |
Domaines de liaison à l'antigène cd98hc et leurs utilisations
|
|
US20240052047A1
(en)
|
2022-08-03 |
2024-02-15 |
Pfizer Inc. |
Anti- il27r antibodies and methods of use thereof
|
|
CA3263767A1
(en)
|
2022-08-03 |
2024-02-08 |
Voyager Therapeutics, Inc. |
COMPOSITIONS AND PROCESSES ALLOWING CROSSING THE BLOOD-BRAIN BARRIER
|
|
WO2024030956A2
(en)
|
2022-08-03 |
2024-02-08 |
Mozart Therapeutics, Inc. |
Cd39-specific binding agents and methods of using the same
|
|
WO2024027815A1
(zh)
|
2022-08-05 |
2024-02-08 |
江苏恒瑞医药股份有限公司 |
特异性结合gucy2c和cd3的抗原结合分子及其医药用途
|
|
KR20250048583A
(ko)
|
2022-08-18 |
2025-04-09 |
리제너론 파아마슈티컬스, 인크. |
인터페론 전구단백질 및 이의 용도
|
|
US20240067691A1
(en)
|
2022-08-18 |
2024-02-29 |
Regeneron Pharmaceuticals, Inc. |
Interferon receptor agonists and uses thereof
|
|
EP4581366A1
(en)
|
2022-09-01 |
2025-07-09 |
Genentech, Inc. |
Therapeutic and diagnostic methods for bladder cancer
|
|
EP4584297A1
(en)
|
2022-09-11 |
2025-07-16 |
Yeda Research and Development Co. Ltd |
Anti-klk4 antibodies and uses thereof
|
|
JP2025535203A
(ja)
|
2022-09-15 |
2025-10-23 |
ボイジャー セラピューティクス インコーポレイテッド |
タウ結合化合物
|
|
EP4587122A1
(en)
|
2022-09-15 |
2025-07-23 |
Avidicure IP B.V. |
Multispecific antigen binding proteins for stimulating nk cells and use thereof
|
|
EP4594353A1
(en)
|
2022-09-28 |
2025-08-06 |
F. Hoffmann-La Roche AG |
Improved protease-activatable t cell bispecific antibodies
|
|
WO2024068996A1
(en)
|
2022-09-30 |
2024-04-04 |
Centre Hospitalier Universitaire Vaudois (C.H.U.V.) |
Anti-sars-cov-2 antibodies and use thereof in the treatment of sars-cov-2 infection
|
|
EP4598958A1
(en)
|
2022-10-05 |
2025-08-13 |
Amgen Inc. |
Combination therapies comprising t-cell redirecting therapies and agonistic anti-il-2r antibodies or fragments thereof
|
|
WO2024077239A1
(en)
|
2022-10-07 |
2024-04-11 |
Genentech, Inc. |
Methods of treating cancer with anti-c-c motif chemokine receptor 8 (ccr8) antibodies
|
|
TW202430211A
(zh)
|
2022-10-10 |
2024-08-01 |
瑞士商赫孚孟拉羅股份公司 |
Gprc5d tcb及imid之組合療法
|
|
TW202423969A
(zh)
|
2022-10-10 |
2024-06-16 |
瑞士商赫孚孟拉羅股份公司 |
Gprc5d tcb及蛋白酶體抑制劑之組合療法
|
|
TW202423970A
(zh)
|
2022-10-10 |
2024-06-16 |
瑞士商赫孚孟拉羅股份公司 |
Gprc5d tcb及cd38抗體之組合療法
|
|
JP2025535744A
(ja)
|
2022-10-12 |
2025-10-28 |
エフ. ホフマン-ラ ロシュ アーゲー |
細胞を分類するための方法
|
|
CN115724975B
(zh)
|
2022-10-20 |
2026-06-09 |
江苏荃信生物医药股份有限公司 |
抗人白介素36受体单克隆抗体及其应用
|
|
WO2024086796A1
(en)
|
2022-10-20 |
2024-04-25 |
Alector Llc |
Anti-ms4a4a antibodies with amyloid-beta therapies
|
|
JP2026500084A
(ja)
|
2022-10-25 |
2026-01-06 |
ジェネンテック, インコーポレイテッド |
多発性骨髄腫の治療方法および診断方法
|
|
US20250382378A1
(en)
|
2022-10-31 |
2025-12-18 |
Genmab A/S |
Cd38 antibodies and uses thereof
|
|
TW202432596A
(zh)
|
2022-11-01 |
2024-08-16 |
大陸商上海齊魯製藥研究中心有限公司 |
針對磷脂醯肌醇蛋白聚醣3的雙特異性抗體及其應用
|
|
IL319999A
(en)
|
2022-11-02 |
2025-06-01 |
Genmab As |
Bispecific antibodies against CD3 and CD20 - for the treatment of Richter syndrome
|
|
WO2024094741A1
(en)
|
2022-11-03 |
2024-05-10 |
F. Hoffmann-La Roche Ag |
Combination therapy with anti-cd19/anti-cd28 bispecific antibody
|
|
IL320029A
(en)
|
2022-11-08 |
2025-06-01 |
Genentech Inc |
Compositions and methods for treating childhood idiopathic nephrotic syndrome
|
|
KR20250134582A
(ko)
|
2022-11-10 |
2025-09-11 |
이뮤비아 인코포레이티드 |
Dr5 및 muc16에 결합하는 세포독성 이중특이성 항체 및 이의 용도
|
|
WO2024100170A1
(en)
|
2022-11-11 |
2024-05-16 |
F. Hoffmann-La Roche Ag |
Antibodies binding to hla-a*02/foxp3
|
|
WO2024102948A1
(en)
|
2022-11-11 |
2024-05-16 |
Celgene Corporation |
Fc receptor-homolog 5 (fcrh5) specific binding molecules and bispecific t-cell engaging antibodies including same and related methods
|
|
CN120187748A
(zh)
|
2022-11-15 |
2025-06-20 |
豪夫迈·罗氏有限公司 |
抗原结合分子
|
|
WO2024104988A1
(en)
|
2022-11-15 |
2024-05-23 |
F. Hoffmann-La Roche Ag |
Recombinant binding proteins with activatable effector domain
|
|
WO2024108053A1
(en)
|
2022-11-17 |
2024-05-23 |
Sanofi |
Ceacam5 antibody-drug conjugates and methods of use thereof
|
|
JP2025538565A
(ja)
|
2022-11-23 |
2025-11-28 |
エフ. ホフマン-ラ ロシュ アーゲー |
組換えタンパク質発現を増加させるための方法
|
|
WO2024111657A1
(ja)
|
2022-11-25 |
2024-05-30 |
中外製薬株式会社 |
タンパク質の製造方法
|
|
WO2024114676A1
(zh)
|
2022-11-29 |
2024-06-06 |
江苏恒瑞医药股份有限公司 |
Cldn18.2/4-1bb结合蛋白及其医药用途
|
|
EP4588936A4
(en)
|
2022-12-08 |
2026-08-12 |
Changchun Bcht Biotechnology Co |
ANTIBODIES THAT BIND SPECIFICALLY TO VRS
|
|
EP4634397A1
(en)
|
2022-12-12 |
2025-10-22 |
Genentech Inc. |
Optimizing polypeptide sialic acid content
|
|
EP4385999A1
(en)
|
2022-12-14 |
2024-06-19 |
ModiQuest B.V. |
Antibodies
|
|
JP2025541200A
(ja)
|
2022-12-15 |
2025-12-18 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
がん処置のための併用療法
|
|
JP2026500017A
(ja)
|
2022-12-16 |
2026-01-05 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
Aav粒子に結合する抗原結合分子及びその使用
|
|
EP4638729A1
(en)
|
2022-12-23 |
2025-10-29 |
Regeneron Pharmaceuticals, Inc. |
Ace2 fusion proteins and uses thereof
|
|
AU2024207005A1
(en)
|
2023-01-13 |
2025-08-28 |
Regeneron Pharmaceuticals, Inc. |
Il12 receptor agonists and methods of use thereof
|
|
CN121002062A
(zh)
|
2023-01-13 |
2025-11-21 |
再生元制药公司 |
Fgfr3结合分子及其使用方法
|
|
PE20252286A1
(es)
|
2023-01-18 |
2025-09-18 |
Genentech Inc |
Anticuerpos multiespecificos y usos de estos
|
|
WO2024153722A1
(en)
|
2023-01-20 |
2024-07-25 |
F. Hoffmann-La Roche Ag |
Immunoconjugates
|
|
CN120603846A
(zh)
|
2023-01-25 |
2025-09-05 |
豪夫迈·罗氏有限公司 |
承载有效载荷的多特异性抗体
|
|
EP4655322A1
(en)
|
2023-01-25 |
2025-12-03 |
F. Hoffmann-La Roche AG |
Antibodies binding to csf1r and cd3
|
|
WO2024163009A1
(en)
|
2023-01-31 |
2024-08-08 |
Genentech, Inc. |
Methods and compositions for treating urothelial bladder cancer
|
|
TW202436339A
(zh)
|
2023-01-31 |
2024-09-16 |
瑞士商赫孚孟拉羅股份公司 |
治療選自非小細胞肺癌或三陰性乳癌的癌症之用途
|
|
CN120584138A
(zh)
|
2023-02-06 |
2025-09-02 |
豪夫迈·罗氏有限公司 |
组合疗法及其用途
|
|
WO2024168061A2
(en)
|
2023-02-07 |
2024-08-15 |
Ayan Therapeutics Inc. |
Antibody molecules binding to sars-cov-2
|
|
WO2024175031A1
(zh)
|
2023-02-21 |
2024-08-29 |
江苏恒瑞医药股份有限公司 |
Il-36r结合蛋白及其医药用途
|
|
AU2024226156A1
(en)
|
2023-02-21 |
2025-08-28 |
Teneobio, Inc. |
C-kit binding proteins, chimeric antigen receptors, and uses thereof
|
|
IL322887A
(en)
|
2023-02-27 |
2025-10-01 |
Suzhou Suncadia Biopharmaceuticals Co Ltd |
Anti-DLL3 antibody, antibody-drug conjugate and pharmaceutical use thereof
|
|
IL322890A
(en)
|
2023-02-28 |
2025-10-01 |
Regeneron Pharma |
Multispecific molecules containing an MHC-peptide complex containing an MHC domain and an antigenic peptide and a partially targeted immune cell antigen
|
|
CN121057744A
(zh)
|
2023-02-28 |
2025-12-02 |
再生元制药公司 |
多价抗刺突蛋白结合分子及其用途
|
|
CN120826234A
(zh)
|
2023-03-06 |
2025-10-21 |
豪夫迈·罗氏有限公司 |
抗EGFRvIII/抗CD3抗体与肿瘤靶向性4-1BB激动剂的组合疗法
|
|
EP4676951A1
(en)
|
2023-03-10 |
2026-01-14 |
Genentech Inc. |
Fusions with proteases and uses thereof
|
|
CN120835901A
(zh)
|
2023-03-13 |
2025-10-24 |
豪夫迈·罗氏有限公司 |
采用pd1-lag3双特异性抗体和hla-g t细胞双特异性抗体的组合疗法
|
|
TW202440636A
(zh)
|
2023-03-21 |
2024-10-16 |
美商傳記55有限公司 |
Cd19/cd38多特異性抗體
|
|
KR20250167591A
(ko)
|
2023-03-31 |
2025-12-01 |
제넨테크, 인크. |
항-알파 v 베타 8 인테그린 항체 및 사용 방법
|
|
EP4688841A1
(en)
|
2023-04-03 |
2026-02-11 |
F. Hoffmann-La Roche AG |
All-in-one agonistic antibodies
|
|
JP2026515642A
(ja)
|
2023-04-03 |
2026-05-19 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
アゴニスト性スプリット抗体
|
|
WO2024211234A1
(en)
|
2023-04-05 |
2024-10-10 |
Sorrento Therapeutics, Inc. |
Antibody-drug conjugates and uses thereof
|
|
TW202506178A
(zh)
|
2023-04-05 |
2025-02-16 |
丹麥商珍美寶股份有限公司 |
包含與cd30和cd3結合之抗體之醫藥組成物
|
|
WO2024211236A2
(en)
|
2023-04-05 |
2024-10-10 |
Sorrento Therapeutics, Inc. |
Antibody-drug conjugates and uses thereof
|
|
CN121985963A
(zh)
|
2023-04-05 |
2026-05-05 |
维硕公司 |
抗体偶联药物及其用途
|
|
EP4442275A1
(en)
|
2023-04-06 |
2024-10-09 |
ModiQuest B.V. |
Anti-type ii collagen antibodies
|
|
CN121175072A
(zh)
|
2023-04-11 |
2025-12-19 |
浙江博锐生物制药有限公司 |
抗ror1抗体及其药物偶联物
|
|
EP4695293A1
(en)
|
2023-04-13 |
2026-02-18 |
Genmab A/S |
Methods of treating lymphoma with bispecific antibodies against cd3 and cd20
|
|
WO2024214811A1
(ja)
|
2023-04-14 |
2024-10-17 |
中外製薬株式会社 |
タンパク質含有医薬製剤の安定化方法
|
|
KR20260012304A
(ko)
|
2023-04-17 |
2026-01-26 |
피크 바이오, 인크. |
항체 및 항체-약물 접합체 및 사용 방법 및 합성 공정 및 중간체
|
|
WO2024233341A1
(en)
|
2023-05-05 |
2024-11-14 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
|
AU2024269754A1
(en)
|
2023-05-08 |
2025-10-23 |
F. Hoffmann-La Roche Ag |
Targeted interferon alpha fusion proteins and methods of use
|
|
AU2024268933A1
(en)
|
2023-05-10 |
2025-11-20 |
Chugai Seiyaku Kabushiki Kaisha |
Methods and compositions for treating cancer
|
|
WO2024233926A1
(en)
|
2023-05-10 |
2024-11-14 |
Regeneron Pharmaceuticals, Inc. |
Cd20-pd1 binding molecules and methods of use thereof
|
|
IL324457A
(en)
|
2023-05-12 |
2026-01-01 |
Genmab As |
Antibodies capable of binding to ox40, their variants and uses thereof
|
|
KR20260026098A
(ko)
|
2023-05-12 |
2026-02-25 |
리제너론 파아마슈티컬스, 인크. |
인터페론 수용체 길항제 및 이의 용도
|
|
JP2026517390A
(ja)
|
2023-05-16 |
2026-05-29 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
Pd-1調節il-2免疫サイトカインおよびその使用
|
|
EP4720124A1
(en)
|
2023-05-24 |
2026-04-08 |
Mozart Therapeutics, Inc. |
Cd8-specific binding proteins and methods of using the same
|
|
TW202504918A
(zh)
|
2023-06-01 |
2025-02-01 |
瑞士商赫孚孟拉羅股份公司 |
靶向bcma及cd28的雙特異性抗體
|
|
EP4720121A1
(en)
|
2023-06-01 |
2026-04-08 |
F. Hoffmann-La Roche AG |
Immunostimulatory antigen binding molecules that specifically bind to bcma
|
|
WO2024251884A1
(en)
|
2023-06-09 |
2024-12-12 |
Innate Pharma |
Nk cell engager proteins comprising anti-cd20 and ant-nkp46 antibody, linked to il-2 in treatment of r/r b-nhl
|
|
CN121646605A
(zh)
|
2023-06-11 |
2026-03-10 |
再生元制药公司 |
环化抗体分子
|
|
CN121399157A
(zh)
|
2023-06-12 |
2026-01-23 |
美国安进公司 |
淋巴毒素β受体激动剂结合蛋白
|
|
JP2026520211A
(ja)
|
2023-06-16 |
2026-06-22 |
ハイデルべルク イミュノセラピューティクス ゲーエムベーハー |
新規の抗hsv抗体
|
|
WO2024261013A1
(en)
|
2023-06-21 |
2024-12-26 |
F. Hoffmann-La Roche Ag |
Combination therapy with fap-targeted lymphotoxin beta receptor agonists
|
|
JP2026522631A
(ja)
|
2023-06-22 |
2026-07-08 |
ジェネンテック, インコーポレイテッド |
抗体及びその使用
|
|
TW202504929A
(zh)
|
2023-06-22 |
2025-02-01 |
美商建南德克公司 |
用於癌症治療之方法及組成物
|
|
WO2024263904A1
(en)
|
2023-06-23 |
2024-12-26 |
Genentech, Inc. |
Methods for treatment of liver cancer
|
|
WO2024263195A1
(en)
|
2023-06-23 |
2024-12-26 |
Genentech, Inc. |
Methods for treatment of liver cancer
|
|
EP4735476A1
(en)
|
2023-06-27 |
2026-05-06 |
Amgen Inc. |
Charge pair mutations to enable correct heavy-light chain pairing
|
|
WO2025007037A1
(en)
|
2023-06-28 |
2025-01-02 |
Dragonfly Therapeutics, Inc. |
Variant il-2 proteins
|
|
TW202509077A
(zh)
|
2023-06-30 |
2025-03-01 |
丹麥商珍美寶股份有限公司 |
與纖維母細胞活化蛋白α及死亡受體4結合之抗體
|
|
KR20260033048A
(ko)
*
|
2023-07-03 |
2026-03-10 |
네오이뮨텍, 인코퍼레이티드 |
이종이합체 fc 분자 및 이의 용도
|
|
US12319747B2
(en)
|
2023-07-03 |
2025-06-03 |
Medicovestor, Inc. |
Methods of using anti-SP17 immunotherapeutics
|
|
US12649790B2
(en)
|
2023-07-03 |
2026-06-09 |
Medicovestor, Inc. |
Proteins that bind SP17 including fully-human anti-SP17 antibodies
|
|
US12624097B2
(en)
|
2023-07-03 |
2026-05-12 |
Medicovestor, Inc. |
Nucleic acids, vectors, and cells that encode anti-Sp17 antibodies and other Sp17 binding proteins
|
|
WO2025024265A1
(en)
|
2023-07-21 |
2025-01-30 |
Bristol-Myers Squibb Company |
Methods of assessing citrullination and activity of pad4 modulators
|
|
PE20260581A1
(es)
|
2023-07-26 |
2026-03-11 |
Hoffmann La Roche |
Anticuerpos que se unen a cd3
|
|
CN121925428A
(zh)
|
2023-07-30 |
2026-04-24 |
詹森生物科技公司 |
结合突变钙网蛋白的分子及其用途
|
|
WO2025034806A1
(en)
|
2023-08-08 |
2025-02-13 |
Wisconsin Alumni Research Foundation |
Single-domain antibodies and variants thereof against fibroblast activation protein
|
|
AU2024323186A1
(en)
|
2023-08-09 |
2026-01-15 |
F. Hoffmann-La Roche Ag |
Mono and multispecific anti-trem2 antibodies, methods and uses thereof
|
|
AU2024320793A1
(en)
|
2023-08-09 |
2026-03-12 |
F. Hoffmann-La Roche Ag |
Mono and multispecific anti-trem2 antibodies, methods and uses thereof
|
|
WO2025038362A1
(en)
|
2023-08-11 |
2025-02-20 |
Merck Sharp & Dohme Llc |
Monovalent interleukin 12 (il-12) heterodimeric fc proteins
|
|
WO2025036892A1
(en)
|
2023-08-14 |
2025-02-20 |
Morphosys Ag |
Cycat halfbody molecules comprising sterically occluding moieties
|
|
KR20260056204A
(ko)
|
2023-08-14 |
2026-04-24 |
보로 테라퓨틱스, 인코포레이티드 |
표적 세포에 대한 골수 세포 활성을 조건부로 촉진시키는 치료용 결합제 및 이의 용도
|
|
TW202508641A
(zh)
|
2023-08-16 |
2025-03-01 |
大陸商上海邁晉生物醫藥科技有限公司 |
一種包含免疫綴合物的醫藥組成物及其用途
|
|
EP4761818A1
(en)
|
2023-08-18 |
2026-06-24 |
F. Hoffmann-La Roche AG |
Protease activatable fc domain binding molecules
|
|
WO2025042428A1
(en)
|
2023-08-18 |
2025-02-27 |
Regeneron Pharmaceuticals, Inc. |
Bispecific antigen-binding molecules and uses thereof
|
|
KR20260057078A
(ko)
|
2023-08-18 |
2026-04-27 |
브리스톨-마이어스 스큅 컴퍼니 |
Bcma 및 cd3에 결합하는 항체를 포함하는 조성물 및 치료 방법
|
|
TW202525845A
(zh)
|
2023-08-23 |
2025-07-01 |
法商賽諾菲公司 |
基於ctla—4之溶體降解劑及其用途
|
|
EP4774301A2
(en)
|
2023-09-08 |
2026-07-15 |
Mlab Biosciences, Inc. |
Bifunctional proteins and uses thereof
|
|
EP4777539A1
(en)
|
2023-09-11 |
2026-07-22 |
Evolveimmune Therapeutics, Inc. |
Bispecific antibody fusion molecules targeting b7-h4 and cd3 and methods of use thereof
|
|
CN121969385A
(zh)
|
2023-09-11 |
2026-05-01 |
丹娜-法伯癌症研究院 |
含有il-2变体以增强car t细胞的功能性的car-衔接子
|
|
WO2025056180A1
(en)
|
2023-09-15 |
2025-03-20 |
BioNTech SE |
Methods of treatment using agents binding to epcam and cd137 in combination with pd-1 axis binding antagonists
|
|
WO2025061032A1
(zh)
|
2023-09-18 |
2025-03-27 |
南京蓬勃生物科技有限公司 |
靶向人源ror1和cd3的双特异性抗体
|
|
CN122094980A
(zh)
|
2023-09-20 |
2026-05-26 |
进化免疫治疗公司 |
靶向cd180和cd3的双特异性抗体融合分子及其使用方法
|
|
EP4780849A1
(en)
|
2023-09-20 |
2026-07-29 |
Evolveimmune Therapeutics, Inc. |
Multispecific antibodies that bind cd3 and cd2 and methods of use thereof
|
|
AR133909A1
(es)
|
2023-09-25 |
2025-11-12 |
Hoffmann La Roche |
ANTICUERPO QUE SE UNE A C3bBb
|
|
AR133955A1
(es)
|
2023-09-26 |
2025-11-19 |
Profoundbio Us Co |
Agentes de unión a ptk7, conjugados de éstos y métodos de uso de los mismos
|
|
CN121843962A
(zh)
|
2023-09-27 |
2026-04-10 |
先声再明医药股份有限公司 |
特异性识别Delta样配体3的单克隆抗体及其应用
|
|
WO2025068957A1
(en)
|
2023-09-29 |
2025-04-03 |
Novartis Ag |
Bispecific antibodies for use in lowering the risk of cardiovascular disease events in subjects known to be a carrier of clonal expansion of hematopoietic cell lines with somatic mutations
|
|
WO2025082777A1
(en)
|
2023-10-17 |
2025-04-24 |
Morphosys Ag |
Dual-targeting of muc16 and mesothelin co-expressing tumor cells by functional complementation of cycat® halfbody molecules
|
|
CN122422333A
(zh)
|
2023-10-17 |
2026-07-17 |
百时美施贵宝公司 |
Gspt1降解化合物、抗cd33抗体和抗体-药物缀合物及其用途
|
|
US12364777B2
(en)
|
2023-10-20 |
2025-07-22 |
Medicovestor, Inc. |
Homodimeric antibodies for use in treating cancers and methods of use
|
|
CN122122176A
(zh)
|
2023-11-03 |
2026-05-29 |
拓济医药(苏州)有限责任公司 |
基于Fc区的异二聚体分子及其用途
|
|
IL328245A
(en)
|
2023-11-08 |
2026-07-01 |
Sanofi Sa |
CD25-based lysosomal compartment and its uses
|
|
IL328096A
(en)
|
2023-11-10 |
2026-06-01 |
Pfizer |
Anti-migis-alpha antibodies and methods of use thereof
|
|
KR20260113057A
(ko)
|
2023-11-14 |
2026-07-21 |
리제너론 파아마슈티컬스, 인크. |
조작된 중쇄 가변 도메인 및 이의 용도
|
|
WO2025106474A1
(en)
|
2023-11-14 |
2025-05-22 |
Genentech, Inc. |
Therapeutic and diagnostic methods for treating cancer with anti-fcrh5/anti-cd3 bispecific antibodies
|
|
WO2025106634A1
(en)
|
2023-11-17 |
2025-05-22 |
Genentech, Inc. |
Mcl-1 inhibitor compounds and use in antibody drug conjugates
|
|
CN122249464A
(zh)
|
2023-11-30 |
2026-06-19 |
金麦安博股份有限公司 |
在组合疗法中的能够结合ox40的抗体
|
|
TW202540200A
(zh)
|
2023-12-01 |
2025-10-16 |
美商基利科學股份有限公司 |
抗fap-light融合蛋白及其用途
|
|
CN122349420A
(zh)
|
2023-12-04 |
2026-07-07 |
山东先声再明生物制药有限公司 |
一种多特异性抗体的组合物及其制备方法和应用
|
|
WO2025122614A1
(en)
|
2023-12-05 |
2025-06-12 |
Regeneron Pharmaceuticals, Inc. |
Il18 receptor agonists and methods of use thereof
|
|
WO2025122634A1
(en)
|
2023-12-05 |
2025-06-12 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of tau-related disorders
|
|
CN122422352A
(zh)
|
2023-12-11 |
2026-07-17 |
豪夫迈·罗氏有限公司 |
蛋白酶可活化的Fc结构域结合分子
|
|
CN122349615A
(zh)
|
2023-12-14 |
2026-07-07 |
基因泰克公司 |
使用抗体进行结构确定的方法
|
|
CN122459340A
(zh)
|
2023-12-14 |
2026-07-24 |
豪夫迈·罗氏有限公司 |
与folr1结合的抗体及使用方法
|
|
CN122422356A
(zh)
|
2023-12-20 |
2026-07-17 |
豪夫迈·罗氏有限公司 |
与ceacam5结合的抗体
|
|
WO2025137086A1
(en)
|
2023-12-20 |
2025-06-26 |
Genentech, Inc. |
Reducing alpha-gal
|
|
AR134814A1
(es)
|
2023-12-21 |
2026-04-15 |
Amgen Inc |
Mutaciones estabilizadoras de homodímeros para la producción de heterodímeros bicelulares
|
|
AU2024402334A1
(en)
|
2023-12-22 |
2026-05-28 |
F. Hoffmann-La Roche Ag |
Activatable fusion proteins and methods of use
|
|
US12116410B1
(en)
|
2023-12-26 |
2024-10-15 |
Medicovestor, Inc. |
Methods of manufacturing dimeric antibodies
|
|
US12673991B2
(en)
|
2023-12-26 |
2026-07-07 |
Medicovestor, Inc. |
Methods of crosslinking IgG
|
|
US12121587B1
(en)
|
2023-12-26 |
2024-10-22 |
Medicovestor, Inc. |
Dimeric antibodies
|
|
US12600795B2
(en)
|
2023-12-26 |
2026-04-14 |
Medicovestor, Inc. |
Oligomeric IgG for immunotherapeutics and diagnostics
|
|
WO2025147696A1
(en)
|
2024-01-05 |
2025-07-10 |
Resolve Therapeutics, Llc |
Treatment of symptoms associated with sars-cov viral infection or a prior sars-cov viral infection with nuclease agents
|
|
TW202547866A
(zh)
|
2024-01-10 |
2025-12-16 |
丹麥商珍美寶股份有限公司 |
Slitrk6結合劑、其共軛物及使用彼之方法
|
|
WO2025149633A1
(en)
|
2024-01-12 |
2025-07-17 |
Laigo Bio B.V. |
Bispecific antigen binding proteins
|
|
CN119431577A
(zh)
|
2024-01-15 |
2025-02-14 |
江苏荃信生物医药股份有限公司 |
抗人cd117单克隆抗体及其应用
|
|
WO2025166042A1
(en)
|
2024-01-31 |
2025-08-07 |
Alector Llc |
Cd98hc antigen-binding domains and uses therefor
|
|
WO2025166045A1
(en)
|
2024-01-31 |
2025-08-07 |
Alector Llc |
β-GLUCOCEREBROSIDASE ENZYMES, FUSION PROTEINS AND COMPLEXES COMPRISING THE SAME, AND METHODS OF USE THEREOF
|
|
WO2025166077A1
(en)
|
2024-01-31 |
2025-08-07 |
Alector Llc |
Compositions comprising progranulin and uses thereof
|
|
WO2025166040A1
(en)
|
2024-01-31 |
2025-08-07 |
Alector Llc |
Multi-specific binding proteins that bind to gpnmb and a blood brain barrier target and methods of use thereof
|
|
US12258396B1
(en)
|
2024-02-02 |
2025-03-25 |
Medicovestor, Inc. |
Methods of using immunotherapeutics that bind folate receptor alpha
|
|
US12378314B1
(en)
|
2024-02-02 |
2025-08-05 |
Medicovestor, Inc. |
Proteins that bind folate receptor alpha including fully-human antibodies
|
|
US12240900B1
(en)
|
2024-02-02 |
2025-03-04 |
Medicovestor, Inc. |
Nucleic acids, vectors, and cells that encode antibodies and other proteins that bind folate receptor alpha
|
|
WO2025174974A1
(en)
|
2024-02-14 |
2025-08-21 |
Bristol-Myers Squibb Company |
Anti-cd33 antibodies and uses thereof
|
|
WO2025172924A1
(en)
|
2024-02-15 |
2025-08-21 |
Janssen Biotech, Inc. |
Anti-transferrin receptor compositions and methods thereof
|
|
WO2025181219A1
(en)
|
2024-02-29 |
2025-09-04 |
Genmab A/S |
Egfr and c-met bispecific binding agents, conjugates thereof and methods of using the same
|
|
WO2025181189A1
(en)
|
2024-03-01 |
2025-09-04 |
F. Hoffmann-La Roche Ag |
Antibodies binding to cd3
|
|
WO2025191133A1
(en)
|
2024-03-15 |
2025-09-18 |
Avidicure Ip B.V. |
Il-21 muteins, fusion proteins comprising the same and uses thereof
|
|
WO2025191136A1
(en)
|
2024-03-15 |
2025-09-18 |
Avidicure Ip B.V. |
Muteins of 4-1bb ligand extracellular domain, fusion proteins comprising the same and uses thereof
|
|
WO2025191139A1
(en)
|
2024-03-15 |
2025-09-18 |
Avidicure Ip B.V. |
Conjugates of her2-specific antigen binding proteins and cytokines
|
|
WO2025199243A1
(en)
|
2024-03-20 |
2025-09-25 |
Regeneron Pharmaceuticals, Inc. |
Trivalent multispecific binding molecules and methods of use thereof
|
|
US20250295801A1
(en)
|
2024-03-21 |
2025-09-25 |
Seagen Inc. |
Cd25 antibodies, antibody drug conjugates, and uses thereof
|
|
WO2025202147A1
(en)
|
2024-03-27 |
2025-10-02 |
F. Hoffmann-La Roche Ag |
Interleukin-7 immunoconjugates
|
|
TW202602940A
(zh)
|
2024-04-09 |
2026-01-16 |
美商安進公司 |
激動性抗il-2rbg重鏈抗體
|
|
WO2025215060A1
(en)
|
2024-04-11 |
2025-10-16 |
F. Hoffmann-La Roche Ag |
Antibodies that specifically bind modified oligonucleotides
|
|
WO2025222129A2
(en)
|
2024-04-19 |
2025-10-23 |
Mozart Therapeutics, Inc. |
Engineered cytokines and targeted cytokine delivery
|
|
WO2025219504A1
(en)
|
2024-04-19 |
2025-10-23 |
F. Hoffmann-La Roche Ag |
Treatment of ophthalmologic diseases
|
|
TW202604943A
(zh)
|
2024-04-24 |
2026-02-01 |
美商建南德克公司 |
治療狼瘡性腎炎之組成物及方法
|
|
WO2025233825A1
(en)
|
2024-05-06 |
2025-11-13 |
Janssen Pharmaceutica Nv |
Enrichment of cells expressing a bird linker
|
|
WO2025233431A1
(en)
|
2024-05-07 |
2025-11-13 |
Immatics Biotechnologies Gmbh |
Heteromeric proteins comprising three heteromerization improving substitution, production, combinations and applications thereof
|
|
WO2025233304A1
(en)
|
2024-05-08 |
2025-11-13 |
F. Hoffmann-La Roche Ag |
Recombinant fc domain – il7 variant polypeptides and combination therapy with membrane-anchored antigen binding polypeptides
|
|
WO2025240335A1
(en)
|
2024-05-13 |
2025-11-20 |
Regeneron Pharmaceuticals, Inc. |
Fgfr3 binding molecules and methods of use thereof
|
|
WO2025240781A2
(en)
|
2024-05-15 |
2025-11-20 |
Werewolf Therapeutics, Inc. |
Modified antibodies and immunoglobulin formats
|
|
WO2025237931A1
(en)
|
2024-05-15 |
2025-11-20 |
F. Hoffmann-La Roche Ag |
Recombinant binding proteins with conditionally activatable t cell and nk cell recruiting effector domains
|
|
WO2025240670A2
(en)
|
2024-05-15 |
2025-11-20 |
Abalytics Oncology, Inc. |
Anti-pd-1 antibodies and related binding molecules and methods and uses thereof
|
|
WO2025238135A2
(en)
|
2024-05-17 |
2025-11-20 |
UCB Biopharma SRL |
Antibody with binding specificity for il-11
|
|
TW202613165A
(zh)
|
2024-05-17 |
2026-04-01 |
比利時商Ucb生物製藥公司 |
具有il-11和il-17結合特異性的多特異性抗體
|
|
TW202606758A
(zh)
|
2024-05-31 |
2026-02-16 |
美商維泰克斯製藥公司 |
抗cd74抗體組合物及方法
|
|
US20250376511A1
(en)
|
2024-06-05 |
2025-12-11 |
Genzyme Corporation |
BINDING PROTEINS THAT TARGET aC1s, TfR, OR BOTH, AND COMPOSITIONS THEREOF
|
|
TW202615453A
(zh)
|
2024-06-05 |
2026-04-16 |
法商賽諾菲公司 |
單特異性及雙特異性tau結合蛋白及其組合物
|
|
US20250376536A1
(en)
|
2024-06-06 |
2025-12-11 |
Bristol-Myers Squibb Company |
Multispecific anti-cd40 / anti-fap antibodies and uses thereof
|
|
WO2025255452A2
(en)
|
2024-06-07 |
2025-12-11 |
Regeneron Pharmaceuticals, Inc. |
Antigen-binding molecules that bind to aav particles and uses thereof
|
|
WO2025255480A1
(en)
|
2024-06-07 |
2025-12-11 |
Regeneron Pharmaceuticals, Inc. |
Tetravalent multispecific binding molecules and methods of use thereof
|
|
US20260055171A1
(en)
|
2024-06-11 |
2026-02-26 |
Regeneron Pharmaceuticals, Inc. |
Vegf antagonists and methods of use thereof
|
|
WO2025257181A1
(en)
|
2024-06-11 |
2025-12-18 |
Institut National de la Santé et de la Recherche Médicale |
Antibodies targeting trans-active response dna-binding protein-43 (tdp-43)
|
|
WO2025259871A1
(en)
|
2024-06-14 |
2025-12-18 |
Gilead Sciences, Inc. |
Anti-ccr8 antibodies and uses thereof
|
|
WO2025256597A1
(en)
|
2024-06-14 |
2025-12-18 |
Keymed Biosciences (Chengdu) Co., Ltd. |
Antibodies targeting ox40l and il-13 and uses thereof
|
|
WO2025264572A1
(en)
|
2024-06-17 |
2025-12-26 |
Alector Llc |
Transferrin receptor antigen-binding domains and uses therefor
|
|
WO2025261943A1
(en)
|
2024-06-18 |
2025-12-26 |
F. Hoffmann-La Roche Ag |
Anti-cancer combinations comprising mosperafenib and folfox or folfiri
|
|
WO2026006162A2
(en)
|
2024-06-24 |
2026-01-02 |
Genentech, Inc. |
B vitamin modulation
|
|
WO2026003224A2
(en)
|
2024-06-26 |
2026-01-02 |
Iomx Therapeutics Ag |
Bispecific antigen binding proteins (abp) targeting immune checkpoint molecules and both leukocyte immunoglobulin-like receptor subfamily b1 (lilrb1) and lilrb2; combinations and uses thereof
|
|
WO2026011013A1
(en)
|
2024-07-02 |
2026-01-08 |
Epibiologics, Inc. |
Binding agents and uses thereof
|
|
WO2026025058A1
(en)
|
2024-07-25 |
2026-01-29 |
Regeneron Pharmaceuticals, Inc. |
Aav viral particles retargeted to egfr-expressing cancer cells
|
|
WO2026030464A1
(en)
|
2024-07-30 |
2026-02-05 |
Genentech, Inc. |
Dosage regimen for reducing cytokine release syndrome (crs) with anti-fcrh5/anti-cd3 bispecific antibodies in multiple myeloma therapy
|
|
WO2026036047A1
(en)
|
2024-08-08 |
2026-02-12 |
Altus Enterprises, Inc. |
Antibody molecules to fixa and fx and uses thereof
|
|
WO2026037938A1
(en)
|
2024-08-16 |
2026-02-19 |
Protuoso Pte. Ltd. |
Fusion proteins comprising a glp-1 receptor agonist and a myostatin pathway inhibitor
|
|
WO2026039791A1
(en)
|
2024-08-16 |
2026-02-19 |
Regeneron Pharmaceuticals, Inc. |
Tumor-targeted split il2 receptor agonists
|
|
WO2026042013A1
(en)
|
2024-08-19 |
2026-02-26 |
Institute Of Molecular And Clinical Ophthalmology Basel (Iob) |
Mitochondrial therapy
|
|
WO2026041568A1
(en)
|
2024-08-20 |
2026-02-26 |
F. Hoffmann-La Roche Ag |
Antibodies binding to cd3 and dotam
|
|
WO2026044177A1
(en)
|
2024-08-23 |
2026-02-26 |
Janssen Biotech, Inc. |
Methods of treatment with gprc5d antibodies with enhanced effector function
|
|
WO2026050572A2
(en)
|
2024-08-29 |
2026-03-05 |
Marengo Therapeutics, Inc. |
Multifunctional molecules binding to tcr and uses thereof
|
|
WO2026052654A1
(en)
|
2024-09-03 |
2026-03-12 |
F. Hoffmann-La Roche Ag |
Cytokine receptor agonist
|
|
WO2026052652A1
(en)
|
2024-09-03 |
2026-03-12 |
F. Hoffmann-La Roche Ag |
Cytokine receptor agonist
|
|
WO2026052756A1
(en)
|
2024-09-05 |
2026-03-12 |
Ablynx Nv |
Her2 binding immunoglobulin single variable domains, constructs comprising the same and uses thereof
|
|
US20260167709A1
(en)
|
2024-09-11 |
2026-06-18 |
Novartis Ag |
Antibodies targeting il-31
|
|
WO2026057723A1
(en)
|
2024-09-12 |
2026-03-19 |
Alentis Therapeutics Ag |
Claudin-1/egfr bispecific antibodies for targeted degradation
|
|
WO2026072685A1
(en)
|
2024-09-25 |
2026-04-02 |
Genentech, Inc. |
Compositions and methods of treating lupus nephritis
|
|
WO2026073816A1
(en)
|
2024-09-25 |
2026-04-09 |
Centre Hospitalier Universitaire Vaudois |
Potency-tuned cd70 ligands, targeted chimeric antigen receptors (cars) and methods for cancer
|
|
WO2026068864A1
(en)
|
2024-09-30 |
2026-04-02 |
BioNTech SE |
Engineered ch1 and cl domains for the prevention of chain mispairing
|
|
WO2026075989A1
(en)
|
2024-10-01 |
2026-04-09 |
Regeneron Pharmaceuticals, Inc. |
Engineered igg molecules and methods of use thereof
|
|
WO2026076013A1
(en)
|
2024-10-01 |
2026-04-09 |
Regeneron Pharmaceuticals, Inc. |
Tumor-targeted il2 receptor agonists and multispecific t-cell engagers
|
|
WO2026073840A1
(en)
|
2024-10-01 |
2026-04-09 |
F. Hoffmann-La Roche Ag |
Antibodies that bind to cd3 and uses therefor
|
|
WO2026078231A1
(en)
|
2024-10-11 |
2026-04-16 |
T-Therapeutics Limited |
Soluble non-aggregating immune ligand
|
|
US20260109746A1
(en)
|
2024-10-22 |
2026-04-23 |
Gilead Sciences, Inc. |
Cd4-targeted il-15 molecules and methods of use
|
|
WO2026087748A1
(en)
|
2024-10-24 |
2026-04-30 |
Avidicure Ip B.V. |
Multispecific antigen binding proteins for the expansion of γδ t cells and use thereof
|
|
WO2026087747A1
(en)
|
2024-10-24 |
2026-04-30 |
Avidicure Ip B.V. |
Multispecific antigen binding proteins for tumor-targeting of γδ1 t cells and use thereof
|
|
WO2026102093A1
(en)
|
2024-11-07 |
2026-05-15 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of tau-related disorders
|
|
WO2026102349A1
(en)
|
2024-11-08 |
2026-05-15 |
Genentech, Inc. |
Anti-interleukin-23 receptor vhh antibodies and uses thereof
|
|
WO2026104330A1
(en)
|
2024-11-12 |
2026-05-21 |
F. Hoffmann-La Roche Ag |
Pd-1-regulated il-2 immunoconjugates and uses thereof
|
|
WO2026104323A1
(en)
|
2024-11-12 |
2026-05-21 |
F. Hoffmann-La Roche Ag |
Targeted flt3l immunoconjugates and methods of use
|
|
WO2026104336A1
(en)
|
2024-11-13 |
2026-05-21 |
F. Hoffmann-La Roche Ag |
Immunoconjugates
|
|
WO2026122400A1
(en)
|
2024-12-03 |
2026-06-11 |
Amgen Inc. |
Bispecific lymphotoxin b receptor binding proteins
|
|
WO2026136279A1
(en)
|
2024-12-16 |
2026-06-25 |
Regeneron Pharmaceuticals, Inc. |
Engineered single domain antibody constructs and methods of use thereof
|
|
WO2026131910A1
(en)
|
2024-12-19 |
2026-06-25 |
F. Hoffmann-La Roche Ag |
Treatment of inflammatory lung disease by combined inhibition of il-33 and il-6 with bispecific antibodies
|
|
WO2026133288A2
(en)
|
2024-12-20 |
2026-06-25 |
Sanofi |
IL-2RβΥ BASED LYSOSOMAL DEGRADER AND USES THEREOF
|
|
WO2026133294A1
(en)
|
2024-12-20 |
2026-06-25 |
Sanofi |
Pd-1/gitr multispecific binding polypeptides and uses thereof
|
|
WO2026132145A1
(en)
|
2024-12-20 |
2026-06-25 |
F. Hoffmann-La Roche Ag |
Antibodies binding to tn-muc-1
|
|
WO2026132383A2
(en)
|
2024-12-20 |
2026-06-25 |
F. Hoffmann-La Roche Ag |
ANTIBODIES BINDING TO Tn-MUC-1
|
|
WO2026132369A1
(en)
|
2024-12-22 |
2026-06-25 |
F. Hoffmann-La Roche Ag |
Method for the generation of a bivalent, bispecific fragment antigen binding expressing mammalian cells
|
|
WO2026151679A1
(en)
|
2025-01-07 |
2026-07-16 |
Compass Therapeutics, Llc. |
Multispecific binding constructs targeting pd-1 and vegf and uses thereof
|
|
WO2026156021A1
(en)
|
2025-01-16 |
2026-07-23 |
Merck Sharp & Dohme Llc |
Bispecific antibody constructs that bind alpp/alppl2 and cd3
|
|
WO2026161391A2
(en)
|
2025-01-21 |
2026-07-30 |
Bristol-Myers Squibb Company |
Cd19 binding molecules including cd3- and cd19- bispecific t cell engagers and related methods and uses
|
|
WO2026161387A1
(en)
|
2025-01-21 |
2026-07-30 |
Bristol-Myers Squibb Company |
Cd3 binding molecules and related methods and uses
|
|
WO2026159103A1
(en)
|
2025-01-23 |
2026-07-30 |
F. Hoffmann-La Roche Ag |
Antibodies binding to cd3
|
|
US20260217815A1
(en)
|
2025-01-29 |
2026-07-30 |
Novartis Ag |
Treatment of atopic dermatitis with multispecific antibodies
|