PL438508A1 - Method for preparing 5-hydroxy-8-methoxyflavone 7-O-β-D-glucoside - Google Patents

Method for preparing 5-hydroxy-8-methoxyflavone 7-O-β-D-glucoside

Info

Publication number
PL438508A1
PL438508A1 PL438508A PL43850821A PL438508A1 PL 438508 A1 PL438508 A1 PL 438508A1 PL 438508 A PL438508 A PL 438508A PL 43850821 A PL43850821 A PL 43850821A PL 438508 A1 PL438508 A1 PL 438508A1
Authority
PL
Poland
Prior art keywords
methoxyflavone
glucoside
hydroxy
preparing
regioselective
Prior art date
Application number
PL438508A
Other languages
Polish (pl)
Other versions
PL247262B1 (en
Inventor
Tomasz Tronina
Monika Mrozowska
Jarosław Popłoński
Sandra Sordon
Mateusz Łużny
Tomasz Janeczko
Ewa Huszcza
Agnieszka Bartmańska
Original Assignee
Uniwersytet Przyrodniczy we Wrocławiu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uniwersytet Przyrodniczy we Wrocławiu filed Critical Uniwersytet Przyrodniczy we Wrocławiu
Priority to PL438508A priority Critical patent/PL247262B1/en
Publication of PL438508A1 publication Critical patent/PL438508A1/en
Publication of PL247262B1 publication Critical patent/PL247262B1/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/06—Benzopyran radicals
    • C07H17/065—Benzo[b]pyrans
    • C07H17/07—Benzo[b]pyran-4-ones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Wynalazek dotyczy sposobu wytwarzania 7-O-β-D-glukozydu 5-hydroksy-8-metoksyflawonu o wzorze 2. Postępując zgodnie z wynalazkiem, w wyniku działania układu enzymatycznego zawartego w komórkach szczepu Beauveria Bassiana AM278, następuje regioselektywna O-glikozylacja w substracie. Uzyskany w ten sposób produkt wydziela się z wodnej kultury mikroorganizmu, znanym sposobem, przez ekstrakcję rozpuszczalnikiem organicznym niemieszającym się z wodą.The invention relates to a method for the production of 5-hydroxy-8-methoxyflavone 7-O-β-D-glucoside of formula 2. Following the invention, regioselective O-glycosylation occurs in the substrate as a result of the action of the enzyme system contained in the cells of Beauveria Bassiana strain AM278. The product thus obtained is isolated from the aqueous culture of the micro-organism in a known manner by extraction with a water-immiscible organic solvent.

PL438508A 2021-07-16 2021-07-16 Method for preparing 5-hydroxy-8-methoxyflavone 7-O-β-D-glucoside PL247262B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL438508A PL247262B1 (en) 2021-07-16 2021-07-16 Method for preparing 5-hydroxy-8-methoxyflavone 7-O-β-D-glucoside

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL438508A PL247262B1 (en) 2021-07-16 2021-07-16 Method for preparing 5-hydroxy-8-methoxyflavone 7-O-β-D-glucoside

Publications (2)

Publication Number Publication Date
PL438508A1 true PL438508A1 (en) 2023-01-23
PL247262B1 PL247262B1 (en) 2025-06-02

Family

ID=84982766

Family Applications (1)

Application Number Title Priority Date Filing Date
PL438508A PL247262B1 (en) 2021-07-16 2021-07-16 Method for preparing 5-hydroxy-8-methoxyflavone 7-O-β-D-glucoside

Country Status (1)

Country Link
PL (1) PL247262B1 (en)

Also Published As

Publication number Publication date
PL247262B1 (en) 2025-06-02

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