ZA200401948B - Polymorphous forms of rifaximin, processes for their production and use thereof in medicinal preparations. - Google Patents
Polymorphous forms of rifaximin, processes for their production and use thereof in medicinal preparations.Info
- Publication number
- ZA200401948B ZA200401948B ZA200401948A ZA200401948A ZA200401948B ZA 200401948 B ZA200401948 B ZA 200401948B ZA 200401948 A ZA200401948 A ZA 200401948A ZA 200401948 A ZA200401948 A ZA 200401948A ZA 200401948 B ZA200401948 B ZA 200401948B
- Authority
- ZA
- South Africa
- Prior art keywords
- rifaximin
- processes
- production
- medicinal preparations
- polymorphous forms
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
-
- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05B—ELECTRIC HEATING; ELECTRIC LIGHT SOURCES NOT OTHERWISE PROVIDED FOR; CIRCUIT ARRANGEMENTS FOR ELECTRIC LIGHT SOURCES, IN GENERAL
- H05B6/00—Heating by electric, magnetic or electromagnetic fields
- H05B6/02—Induction heating
- H05B6/10—Induction heating apparatus, other than furnaces, for specific applications
- H05B6/12—Cooking devices
- H05B6/1209—Cooking devices induction cooking plates or the like and devices to be used in combination with them
- H05B6/1236—Cooking devices induction cooking plates or the like and devices to be used in combination with them adapted to induce current in a coil to supply power to a device and electrical heating devices powered in this way
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05B—ELECTRIC HEATING; ELECTRIC LIGHT SOURCES NOT OTHERWISE PROVIDED FOR; CIRCUIT ARRANGEMENTS FOR ELECTRIC LIGHT SOURCES, IN GENERAL
- H05B6/00—Heating by electric, magnetic or electromagnetic fields
- H05B6/02—Induction heating
- H05B6/10—Induction heating apparatus, other than furnaces, for specific applications
- H05B6/12—Cooking devices
- H05B6/1209—Cooking devices induction cooking plates or the like and devices to be used in combination with them
- H05B6/1245—Cooking devices induction cooking plates or the like and devices to be used in combination with them with special coil arrangements
- H05B6/1263—Cooking devices induction cooking plates or the like and devices to be used in combination with them with special coil arrangements using coil cooling arrangements
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Physics & Mathematics (AREA)
- Electromagnetism (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT002144A ITMI20032144A1 (it) | 2003-11-07 | 2003-11-07 | Forme polimorfe di rifaximina, processi per ottenerle e |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200401948B true ZA200401948B (en) | 2004-04-29 |
Family
ID=33187382
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200401948A ZA200401948B (en) | 2003-11-07 | 2004-03-10 | Polymorphous forms of rifaximin, processes for their production and use thereof in medicinal preparations. |
Country Status (37)
| Country | Link |
|---|---|
| US (5) | US7045620B2 (fr) |
| EP (6) | EP1676847B1 (fr) |
| JP (5) | JP2005139161A (fr) |
| KR (4) | KR20050043589A (fr) |
| CN (4) | CN1613858A (fr) |
| AR (3) | AR043547A1 (fr) |
| AT (3) | ATE361927T1 (fr) |
| AU (2) | AU2004200964A1 (fr) |
| BR (2) | BRPI0402382A (fr) |
| CA (2) | CA2460384A1 (fr) |
| CL (1) | CL2004000498A1 (fr) |
| CO (1) | CO5560083A1 (fr) |
| CY (3) | CY1108017T1 (fr) |
| DE (4) | DE602004006367C5 (fr) |
| DK (3) | DK1676847T3 (fr) |
| ES (3) | ES2244364T3 (fr) |
| HR (2) | HRP20040265A2 (fr) |
| IL (2) | IL160798A0 (fr) |
| IT (1) | ITMI20032144A1 (fr) |
| JO (1) | JO2470B1 (fr) |
| MA (1) | MA27069A1 (fr) |
| MD (1) | MD3653G8 (fr) |
| ME (1) | ME00424B (fr) |
| MX (2) | MXPA04002353A (fr) |
| NO (1) | NO334950B1 (fr) |
| NZ (1) | NZ531622A (fr) |
| PL (3) | PL1676847T3 (fr) |
| PT (3) | PT1557421E (fr) |
| RS (4) | RS54571B1 (fr) |
| RU (1) | RU2270200C2 (fr) |
| SI (3) | SI1557421T1 (fr) |
| TN (2) | TNSN04044A1 (fr) |
| TW (1) | TWI285107B (fr) |
| UA (1) | UA86384C2 (fr) |
| WO (1) | WO2005044823A2 (fr) |
| YU (1) | YU24804A (fr) |
| ZA (1) | ZA200401948B (fr) |
Families Citing this family (84)
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|---|---|---|---|---|
| US6861053B1 (en) | 1999-08-11 | 2005-03-01 | Cedars-Sinai Medical Center | Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth |
| US7048906B2 (en) * | 1995-05-17 | 2006-05-23 | Cedars-Sinai Medical Center | Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions |
| US7902206B2 (en) * | 2003-11-07 | 2011-03-08 | Alfa Wassermann, S.P.A. | Polymorphic forms α, β and γ of rifaximin |
| US7923553B2 (en) * | 2003-11-07 | 2011-04-12 | Alfa Wassermann, S.P.A. | Processes for the production of polymorphic forms of rifaximin |
| US7906542B2 (en) * | 2004-11-04 | 2011-03-15 | Alfa Wassermann, S.P.A. | Pharmaceutical compositions comprising polymorphic forms α, β, and γ of rifaximin |
| ITMI20032144A1 (it) | 2003-11-07 | 2005-05-08 | Alfa Wassermann Spa | Forme polimorfe di rifaximina, processi per ottenerle e |
| US20080262024A1 (en) * | 2003-11-07 | 2008-10-23 | Giuseppe Claudio Viscomi | Rifaximin compositions and method of use |
| PT1698630E (pt) * | 2005-03-03 | 2014-09-15 | Alfa Wassermann Spa | Novas formas polimorfas de rifaximina, processos para a sua produção e a sua utilização nas preparações medicinais |
| ITBO20050123A1 (it) | 2005-03-07 | 2005-06-06 | Alfa Wassermann Spa | Formulazioni farmaceutiche gastroresistenti contenenti rifaximina |
| MX2009001342A (es) | 2006-08-02 | 2009-08-31 | Salix Pharmaceuticals Inc | Composiciones y metodos para el tratamiento de proctosigmoiditis por radiacion. |
| ITMI20061692A1 (it) * | 2006-09-05 | 2008-03-06 | Alfa Wassermann Spa | Uso di polioli per ottenere forme polimorfe stabili di rifaximina |
| EP2069363B1 (fr) * | 2006-09-22 | 2013-03-20 | Cipla Ltd. | Rifaximine sous une forme amorphe |
| US20080161337A1 (en) * | 2007-01-03 | 2008-07-03 | Leonard Weinstock | Use of Rifaximin for the Treatment of Chronic Prostatitis |
| US20080159987A1 (en) * | 2007-01-03 | 2008-07-03 | Leonard Weinstock | Use of Rifaximin for the Treatment of Restless Legs Syndrome |
| ITMI20071241A1 (it) * | 2007-06-20 | 2008-12-21 | Solmag S P A | Processo per la preparazione di rifaximina amorfa e rifaximina amorfa cosi' ottenuta |
| AU2016203925B2 (en) * | 2007-07-06 | 2016-10-20 | Lupin Limited | Pharmaceutical compositions of rifaximin |
| JP5755878B2 (ja) * | 2007-07-06 | 2015-07-29 | ルパン リミテッドLupin Limited | リファキシミンの薬剤組成物 |
| ES2798253T3 (es) * | 2007-07-06 | 2020-12-10 | Lupin Ltd | Composiciones farmacéuticas de rifaximina |
| US7709634B2 (en) * | 2007-09-20 | 2010-05-04 | Apotex Pharmachem Inc. | Amorphous form of rifaximin and processes for its preparation |
| US8486956B2 (en) * | 2008-02-25 | 2013-07-16 | Salix Pharmaceuticals, Ltd | Forms of rifaximin and uses thereof |
| US8067429B2 (en) * | 2008-02-25 | 2011-11-29 | Salix Pharmaceuticals, Ltd. | Forms of rifaximin and uses thereof |
| PT2252148T (pt) * | 2008-02-26 | 2020-01-23 | Salix Pharmaceuticals Ltd | Métodos de tratamento da síndrome do intestino irritável |
| US11779571B2 (en) * | 2008-02-26 | 2023-10-10 | Salix Pharmaceuticals, Inc. | Methods for treating irritable bowel syndrome (IBS) |
| HRP20140939T1 (hr) | 2008-05-07 | 2014-11-21 | Salix Pharmaceuticals, Ltd. | Davanje preparata za äśišä†enje crijeva i antibiotika za lijeäśenje bolesti crijeva |
| AU2009297562B2 (en) | 2008-09-26 | 2015-04-23 | Alfasigma S.P.A. | Agent for preventing and/or treating functional gastrointestinal disorder |
| US20100317681A1 (en) * | 2009-06-15 | 2010-12-16 | Salix Pharmaceuticals, Ltd. | Modulation of systemic exposure to rifaximin |
| US12285414B2 (en) | 2008-10-02 | 2025-04-29 | Salix Pharmaceuticals, Inc. | Methods of treating hepatic encephalopathy |
| US20110035232A1 (en) | 2008-10-02 | 2011-02-10 | Salix Pharmaceuticals, Ltd. | Methods of treating hepatic encephalopathy |
| US7928115B2 (en) | 2008-10-02 | 2011-04-19 | Salix Pharmaceuticals, Ltd. | Methods of treating travelers diarrhea and hepatic encephalopathy |
| BRPI0920465A2 (pt) | 2008-10-02 | 2018-03-20 | Salix Pharmaceuticals, Inc. | metodo de tratamento de encefalopatia hepática |
| US8916193B2 (en) | 2008-12-10 | 2014-12-23 | Cipla Limited | Rifaximin complexes |
| IT1397617B1 (it) * | 2009-04-20 | 2013-01-18 | Alfa Wassermann Spa | Nuovi derivati della rifamicina |
| KR20190099100A (ko) | 2009-06-02 | 2019-08-23 | 샐릭스 파마슈티컬스 리미티드 | 간성 뇌병증의 치료방법 |
| NZ598671A (en) | 2009-09-13 | 2014-02-28 | Salix Pharmaceuticals Ltd | Methods for treating irritable bowel syndrome (ibs) |
| RU2012121599A (ru) * | 2009-10-27 | 2013-12-10 | Люпин Лимитед | Твердая дисперсия рифаксимина |
| WO2011061748A1 (fr) * | 2009-11-19 | 2011-05-26 | Strides Arcolab Limited | Prémélange à base de rifaximine |
| EP2503989A2 (fr) | 2009-11-23 | 2012-10-03 | Cipla Limited | Composition de mousse topique |
| US8952159B2 (en) | 2009-12-28 | 2015-02-10 | Silvio Massimo Lavagna | Method for the production of amorphous rifaximin |
| AU2011218129A1 (en) | 2010-02-18 | 2012-08-23 | Board Of Regents Of The University Of Texas System | Methods for treating infection |
| IT1398550B1 (it) | 2010-03-05 | 2013-03-01 | Alfa Wassermann Spa | Formulazioni comprendenti rifaximina utili per ottenere un effetto prolungato nel tempo |
| WO2011153444A1 (fr) * | 2010-06-03 | 2011-12-08 | Salix Pharmaceuticals, Ltd | Nouvelles formes de la rifaximine et leurs utilisations |
| CA2802874A1 (fr) * | 2010-06-16 | 2011-12-22 | Apotex Pharmachem Inc. | Formes polymorphiques de rifaximine |
| SMT202000390T1 (it) * | 2010-07-12 | 2020-09-10 | Salix Pharmaceuticals Inc | Formulazioni di rifaximina e loro usi |
| WO2012035544A2 (fr) | 2010-09-13 | 2012-03-22 | Sequent Scientific Ltd. | Nouvelle forme polymorphe de rifaximine et son procédé de préparation |
| IT1403847B1 (it) | 2010-09-22 | 2013-11-08 | Alfa Wassermann Spa | Composizioni farmaceutiche comprendenti rifaximina e loro uso. |
| WO2012060675A1 (fr) * | 2010-11-05 | 2012-05-10 | Interquim, S.A. De C.V. | Procédé de préparation de rifaximine amorphe |
| WO2012076832A1 (fr) * | 2010-12-09 | 2012-06-14 | Cipla Limited | Suppositoires contenant de la rifaximine |
| WO2012109605A2 (fr) | 2011-02-11 | 2012-08-16 | Salix Pharmaceuticals, Ltd. | Formes de rifaximine et leurs utilisations |
| CA2834829A1 (fr) | 2011-05-02 | 2012-11-08 | Ranbaxy Laboratories Limited | Solvate de dimethylformamide rifaximine |
| WO2012155981A1 (fr) | 2011-05-19 | 2012-11-22 | Friulchem Spa | Nouveau procédé pour la synthèse de rifaximine et nouvelle forme pseudo-cristalline de rifaximine obtenue au moyen de celui-ci |
| ITMI20110890A1 (it) * | 2011-05-19 | 2012-11-20 | A M S A Anonima Materie Sint & Affini S P A | Polimorfo di rifaximina e processo per la sua preparazione |
| ITBO20110461A1 (it) | 2011-07-29 | 2013-01-30 | Alfa Wassermann Spa | Composizioni farmaceutiche comprendenti rifaximina, processi per la loro preparazione e loro uso nel trattamento di infezioni vaginali. |
| US20130184302A1 (en) * | 2011-11-02 | 2013-07-18 | Enoch Bortey | Methods for treating irritable bowel syndrome (ibs) and infections |
| JP2013184902A (ja) * | 2012-03-06 | 2013-09-19 | Aska Pharmaceutical Co Ltd | リファキシミン含有結晶 |
| US9359374B2 (en) | 2012-06-13 | 2016-06-07 | Apotex Pharmachem Inc. | Polymorphic forms of rifaximin |
| ITBO20120368A1 (it) | 2012-07-06 | 2014-01-07 | Alfa Wassermann Spa | Composizioni comprendenti rifaximina e amminoacidi, cristalli di rifaximina derivanti da tali composizioni e loro uso. |
| US9849090B2 (en) | 2012-12-12 | 2017-12-26 | Sun Pharmaceutical Industries Limited | Pharmaceutical compositions of rifaximin |
| US20160047819A1 (en) | 2013-03-15 | 2016-02-18 | Alfa Wassermann S.P.A. | Method for diagnosing vaginal infections |
| US20160038468A1 (en) | 2013-03-15 | 2016-02-11 | Alfa Wassermann S.P.A. | Rifaximin for use in the treating of vaginal infections |
| CN105324109A (zh) | 2013-04-12 | 2016-02-10 | 意大利阿尔法韦士曼制药公司 | Nsaid施用和相关的组合物、方法和系统 |
| US9018225B1 (en) | 2013-07-26 | 2015-04-28 | Novel Laboratories | Rifaximin crystalline forms and methods of preparation thereof |
| EP2927235B1 (fr) | 2014-03-31 | 2017-02-08 | Euticals S.P.A. | Mélange de polymorphes de rifaximine et son utilisation pour la préparation de formulations solides |
| US9765088B2 (en) | 2014-04-19 | 2017-09-19 | Granules India Limited | Process for the preparation of rifamycin derivatives |
| CA2947962C (fr) | 2014-05-04 | 2024-01-16 | Salix Pharmaceuticals, Inc. | Microbiote du syndrome du colon irritable et utilisations associees |
| AU2015260837B2 (en) | 2014-05-12 | 2019-02-28 | Alfasigma S.P.A. | New solvated crystal form of rifaximin, production, compositions and uses thereof |
| MX381919B (es) * | 2014-06-30 | 2025-03-13 | Salix Pharmaceuticals Inc | Métodos para repetir tratamiento de síndrome del intestino irritable (ibs). |
| CN104083324B (zh) * | 2014-07-10 | 2017-05-10 | 青岛动保国家工程技术研究中心有限公司 | 一种利福昔明的兽用悬乳剂及其制备方法和应用 |
| EP2982764A1 (fr) | 2014-08-05 | 2016-02-10 | ALFA WASSERMANN S.p.A. | Identification de bactérie vaginale |
| CN104274391B (zh) * | 2014-10-08 | 2017-02-01 | 哈尔滨坤盟医药科技有限公司 | 一种含利福昔明的药物制剂 |
| WO2017021975A1 (fr) * | 2015-08-06 | 2017-02-09 | Msn Laboratories Private Limited | Procédé de préparation de formes cristallines de rifaximine |
| HUE040253T2 (hu) | 2016-03-24 | 2019-02-28 | Sandoz Ag | Rifaximin alfa&deltát tartalmazó gyógyászati készítmény |
| HUE044432T2 (hu) | 2016-03-24 | 2019-10-28 | Sandoz Ag | Rifaximin alfá-t tartalmazó, hosszan eltartható kompozíció |
| US9988398B2 (en) * | 2016-06-07 | 2018-06-05 | Cadila Healthcare Limited | Crystalline form of rifaximin and process for its preparation |
| CA3038312A1 (fr) | 2016-09-30 | 2018-04-05 | Salix Pharmaceuticals, Inc. | Formes de dispersions solides de rifaximine |
| CN106632396B (zh) * | 2017-01-06 | 2019-01-11 | 成都樵枫科技发展有限公司 | γ晶型利福昔明的制备方法和用途 |
| CA3013161C (fr) | 2017-04-26 | 2020-03-24 | Sandoz Ag | Forme de dosage orale comprenant du rifaximine sous forme beta |
| RU2020102511A (ru) | 2017-06-26 | 2021-07-27 | Биофер С.П.А. | Соединения пиридо-имидазо рифамицина в качестве антибактериального средства |
| US20220062183A1 (en) * | 2018-12-19 | 2022-03-03 | Friulchem S.P.A. | Process for the manufacture of a tablet of rifaximin and tablet of rifaximin |
| CA3142214A1 (fr) | 2019-06-03 | 2020-12-10 | Bausch Health Ireland Limited | Utilisation de methylnaltrexone et de rifaximine pour le traitement d'une permeabilite intestinale accrue ou de troubles associes |
| MX427410B (es) | 2019-09-24 | 2025-10-13 | Bausch Health Ireland Ltd | Formulaciones liquidas de rifaximina |
| WO2021191312A1 (fr) | 2020-03-24 | 2021-09-30 | Bausch Health Ireland Limited | Procédés de traitement de la covid-19 avec de la rifaximine |
| WO2021229480A1 (fr) * | 2020-05-15 | 2021-11-18 | Atra Pharmaceuticals Limited | Polymorphe de la rifaximine, son procédé de préparation et composition pharmaceutique contenant de la rifaximine |
| CA3184054A1 (fr) | 2020-06-26 | 2021-12-30 | Jacob Cole | Compositions de rifaximine a liberation ciblee |
| US20230398102A1 (en) | 2020-10-29 | 2023-12-14 | Bausch Health Ireland Limited | Rifaximin liquid formulations for use inthe treatment of sickle cell disease |
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| US20050262269A1 (en) | 2004-05-20 | 2005-11-24 | Pike Jimmy D | System and method for information handling system PCI express advanced switching |
| PT1698630E (pt) | 2005-03-03 | 2014-09-15 | Alfa Wassermann Spa | Novas formas polimorfas de rifaximina, processos para a sua produção e a sua utilização nas preparações medicinais |
| EP2069363B1 (fr) | 2006-09-22 | 2013-03-20 | Cipla Ltd. | Rifaximine sous une forme amorphe |
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| ES2798253T3 (es) | 2007-07-06 | 2020-12-10 | Lupin Ltd | Composiciones farmacéuticas de rifaximina |
| JP5755878B2 (ja) | 2007-07-06 | 2015-07-29 | ルパン リミテッドLupin Limited | リファキシミンの薬剤組成物 |
| US7709634B2 (en) | 2007-09-20 | 2010-05-04 | Apotex Pharmachem Inc. | Amorphous form of rifaximin and processes for its preparation |
| WO2009047801A1 (fr) | 2007-10-10 | 2009-04-16 | Lupin Limited | Combinaisons thérapeutiques et compositions pour le traitement de troubles gastro-intestinaux |
| US8067429B2 (en) | 2008-02-25 | 2011-11-29 | Salix Pharmaceuticals, Ltd. | Forms of rifaximin and uses thereof |
-
2003
- 2003-11-07 IT IT002144A patent/ITMI20032144A1/it unknown
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2004
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2005
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2006
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2007
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2009
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2010
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2011
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2014
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