ATE128737T1 - Strangverdrängungsamplifikation. - Google Patents

Strangverdrängungsamplifikation.

Info

Publication number: ATE128737T1
Authority: AT; Austria
Prior art keywords: strand displacement; displacement amplification; strand; polymerase; polymerized
Prior art date: 1991-01-31

Application number

AT92101348T

Other languages

English (en)

Inventor

George T Walker

Original Assignee

Becton Dickinson Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-01-31

Filing date

1992-01-28

Publication date

1995-10-15

1992-01-28 Application filed by Becton Dickinson Co filed Critical Becton Dickinson Co

1995-10-15 Application granted granted Critical

1995-10-15 Publication of ATE128737T1 publication Critical patent/ATE128737T1/de

Links

230000003321 amplification Effects 0.000 title abstract 2
238000003199 nucleic acid amplification method Methods 0.000 title abstract 2
238000006073 displacement reaction Methods 0.000 title 1
102000004533 Endonucleases Human genes 0.000 abstract 1
108010042407 Endonucleases Proteins 0.000 abstract 1
238000001514 detection method Methods 0.000 abstract 1
230000029087 digestion Effects 0.000 abstract 1
150000007523 nucleic acids Chemical class 0.000 abstract 1
102000039446 nucleic acids Human genes 0.000 abstract 1
108020004707 nucleic acids Proteins 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Microbiology (AREA)
Biophysics (AREA)
Analytical Chemistry (AREA)
Physics & Mathematics (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Superconductors And Manufacturing Methods Therefor (AREA)
Materials For Medical Uses (AREA)
Surgical Instruments (AREA)
Silicon Polymers (AREA)
Crystals, And After-Treatments Of Crystals (AREA)

AT92101348T 1991-01-31 1992-01-28 Strangverdrängungsamplifikation. ATE128737T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US64825791A	1991-01-31	1991-01-31
US07/819,358 US5455166A (en)	1991-01-31	1992-01-09	Strand displacement amplification

Publications (1)

Publication Number	Publication Date
ATE128737T1 true ATE128737T1 (de)	1995-10-15

Family

ID=27095344

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT92101348T ATE128737T1 (de)	1991-01-31	1992-01-28	Strangverdrängungsamplifikation.

Country Status (11)

Country	Link
US (2)	US5455166A (de)
EP (1)	EP0497272B1 (de)
JP (1)	JPH07114718B2 (de)
KR (1)	KR950003619B1 (de)
AT (1)	ATE128737T1 (de)
AU (1)	AU659429B2 (de)
CA (1)	CA2060372C (de)
DE (1)	DE69205181T2 (de)
DK (1)	DK0497272T3 (de)
ES (1)	ES2077887T3 (de)
GR (1)	GR3018271T3 (de)

Families Citing this family (905)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1992005287A1 (en) *	1990-09-21	1992-04-02	Amgen Inc.	Enzymatic synthesis of oligonucleotides
US5645987A (en) *	1990-09-21	1997-07-08	Amgen Inc.	Enzymatic synthesis of oligonucleotides
US5270184A (en) *	1991-11-19	1993-12-14	Becton, Dickinson And Company	Nucleic acid target generation
US5733733A (en) *	1992-08-04	1998-03-31	Replicon, Inc.	Methods for the isothermal amplification of nucleic acid molecules
US5834202A (en)	1992-08-04	1998-11-10	Replicon, Inc.	Methods for the isothermal amplification of nucleic acid molecules
US6261808B1 (en)	1992-08-04	2001-07-17	Replicon, Inc.	Amplification of nucleic acid molecules via circular replicons
WO1994003624A1 (en) *	1992-08-04	1994-02-17	Auerbach Jeffrey I	Methods for the isothermal amplification of nucleic acid molecules
ZA936015B (en) *	1992-08-24	1994-03-10	Akzo Nv	Elimination of false negatives in nuleic acid detection.
CA2119188A1 (en) *	1993-04-05	1994-10-06	Patricia A. Spears	Detection and identification of mycobacteria
US5422252A (en) *	1993-06-04	1995-06-06	Becton, Dickinson And Company	Simultaneous amplification of multiple targets
US5470723A (en) *	1993-05-05	1995-11-28	Becton, Dickinson And Company	Detection of mycobacteria by multiplex nucleic acid amplification
US6890712B1 (en) *	1993-09-22	2005-05-10	Bioveris Corporation	Cycling DNA/RNA amplification electrochemiluminescent probe assay
US6986985B1 (en) *	1994-01-13	2006-01-17	Enzo Life Sciences, Inc.	Process for producing multiple nucleic acid copies in vivo using a protein-nucleic acid construct
US20050123926A1 (en) *	1994-01-13	2005-06-09	Enzo Diagnostics, Inc.,	In vitro process for producing multiple nucleic acid copies
CA2140081C (en) *	1994-01-13	2008-04-01	Dean L. Engelhardt	Process, construct and conjugate for producing multiple nucleic acid copies
US20110097791A1 (en) *	1999-04-16	2011-04-28	Engelhardt Dean L	Novel process, construct and conjugate for producing multiple nucleic acid copies
JPH09510351A (ja) *	1994-03-16	1997-10-21	ジェン−プローブ・インコーポレイテッド	等温鎖置換核酸増幅法
US6100078A (en) *	1994-04-01	2000-08-08	Gen-Probe Incorporated	Purified DNA polymerase from bacillus stearothermophilus ATCC 12980
US5648211A (en) *	1994-04-18	1997-07-15	Becton, Dickinson And Company	Strand displacement amplification using thermophilic enzymes
US5547861A (en) *	1994-04-18	1996-08-20	Becton, Dickinson And Company	Detection of nucleic acid amplification
US5658729A (en) *	1994-10-11	1997-08-19	The University Of British Columbia	Method, reagent and kit for evaluating susceptibility to premature atherosclerosis
CA2150986C (en) *	1994-06-17	1999-11-02	Mary Kathryn Meyer	Oligonucleotide primers and probes for detection of bacteria
AU4586096A (en) *	1995-03-10	1996-09-19	Becton Dickinson & Company	Sample processing method for whole blood
AUPN245295A0 (en) *	1995-04-13	1995-05-11	Johnson & Johnson Research Pty. Limited	Assay for genetic abnormalities
US5753439A (en) *	1995-05-19	1998-05-19	Trustees Of Boston University	Nucleic acid detection methods
US5705365A (en) *	1995-06-07	1998-01-06	Gen-Probe Incorporated	Kits for determining pre-amplification levels of a nucleic acid target sequence from post-amplification levels of product
WO1996040992A2 (en) *	1995-06-07	1996-12-19	Abbott Laboratories	Probe masking method of reducing background in an amplification reaction
US5710029A (en) *	1995-06-07	1998-01-20	Gen-Probe Incorporated	Methods for determining pre-amplification levels of a nucleic acid target sequence from post-amplification levels of product
US5882867A (en) *	1995-06-07	1999-03-16	Dade Behring Marburg Gmbh	Detection of nucleic acids by formation of template-dependent product
AT402203B (de) *	1995-06-13	1997-03-25	Himmler Gottfried Dipl Ing Dr	Verfahren zur transkriptionsfreien amplifizierung von nucleinsäuren
WO1997003348A1 (en) *	1995-07-13	1997-01-30	Immunological Associates Of Denver	Self-contained device integrating nucleic acid extraction, amplification and detection
US5989813A (en) *	1995-07-13	1999-11-23	Molecular Innovations, Inc.	Detection of amplified nucleic acid sequences using bifunctional haptenization and dyed microparticles
US5916779A (en) *	1995-09-21	1999-06-29	Becton, Dickinson And Company	Strand displacement amplification of RNA targets
US5641633A (en) *	1995-11-15	1997-06-24	Becton, Dickinson And Company	Fluorescence polarization detection of nucleic acids
US5800989A (en) *	1995-11-15	1998-09-01	Becton, Dickinson And Company	Method for detection of nucleic acid targets by amplification and fluorescence polarization
US6143495A (en) *	1995-11-21	2000-11-07	Yale University	Unimolecular segment amplification and sequencing
US5854033A (en)	1995-11-21	1998-12-29	Yale University	Rolling circle replication reporter systems
ATE238434T1 (de)	1995-12-05	2003-05-15	Jorn Erland Koch	Eine in kaskaden verlaufende vervielfältigungsreaktion von nukleinsäuren
CA2249717A1 (en) *	1996-03-18	1997-09-25	Richard K. Wilkosz	Target nucleic acid sequence amplification
US5712127A (en)	1996-04-29	1998-01-27	Genescape Inc.	Subtractive amplification
AU2849197A (en) *	1996-07-17	1998-01-29	Becton Dickinson & Company	Thermophilic strand displacement amplifications using AvaI
JP2000516468A (ja)	1996-08-14	2000-12-12	ライフテクノロジーズ，インコーポレイテッド	核酸増幅および配列決定のための安定な組成物
DE19633427C2 (de) *	1996-08-20	2001-10-04	Hubert S Bernauer	Verfahren zur Synthese von Nukleinsäuremolekülen mit zumindest teilweise vorbestimmter Nukleotidsequenz
US5702926A (en) *	1996-08-22	1997-12-30	Becton, Dickinson And Company	Nicking of DNA using boronated nucleotides
AU4174397A (en) *	1996-08-30	1998-03-19	Life Technologies, Inc.	Methods for identification and isolation of specific nucleotide sequences in cdna and genomic dna
US5858671A (en) *	1996-11-01	1999-01-12	The University Of Iowa Research Foundation	Iterative and regenerative DNA sequencing method
US6096273A (en) *	1996-11-05	2000-08-01	Clinical Micro Sensors	Electrodes linked via conductive oligomers to nucleic acids
US7381525B1 (en) *	1997-03-07	2008-06-03	Clinical Micro Sensors, Inc.	AC/DC voltage apparatus for detection of nucleic acids
GB9624165D0 (en) *	1996-11-19	1997-01-08	Amdex A S	Use of nucleic acids bound to carrier macromolecules
AU746549B2 (en)	1996-11-20	2002-05-02	Becton Dickinson & Company	Microfabricated isothermal nucleic acid amplification devices and methods
US20040142327A1 (en) *	1996-11-22	2004-07-22	Jhy-Jhu Lin	Methods for identifying and isolating DNA polymorphisms or genetic markers
US6306588B1 (en)	1997-02-07	2001-10-23	Invitrogen Corporation	Polymerases for analyzing or typing polymorphic nucleic acid fragments and uses thereof
US6197557B1 (en)	1997-03-05	2001-03-06	The Regents Of The University Of Michigan	Compositions and methods for analysis of nucleic acids
US6117634A (en) *	1997-03-05	2000-09-12	The Reagents Of The University Of Michigan	Nucleic acid sequencing and mapping
EP1005481B1 (de)	1997-04-22	2009-10-14	Life Technologies Corporation	Verfahren zur herstellung von aslv reverser transkriptase zusammengestellt aus mehreren untereinheiten
US5863736A (en) *	1997-05-23	1999-01-26	Becton, Dickinson And Company	Method, apparatus and computer program products for determining quantities of nucleic acid sequences in samples
US6503709B1 (en)	1997-07-03	2003-01-07	Id Biomedical Corporation	Methods for rapidly detecting methicillin resistant staphylococci
AU9660698A (en) *	1997-08-29	1999-03-16	Osvaldo J. Lopez	Dna methyltransferase genotyping
EP1012344A4 (de)	1997-09-12	2004-08-11	Public Health Res Instituteof	Nicht-kompetitive co-amplifizierungsmethoden
US5935791A (en) *	1997-09-23	1999-08-10	Becton, Dickinson And Company	Detection of nucleic acids by fluorescence quenching
WO1999037819A2 (en) *	1998-01-27	1999-07-29	Clinical Micro Sensors, Inc.	Amplification of nucleic acids with electronic detection
US6686150B1 (en) *	1998-01-27	2004-02-03	Clinical Micro Sensors, Inc.	Amplification of nucleic acids with electronic detection
US6787305B1 (en)	1998-03-13	2004-09-07	Invitrogen Corporation	Compositions and methods for enhanced synthesis of nucleic acid molecules
DE19812103A1 (de) *	1998-03-19	1999-09-23	Bernauer Annette	Verfahren zur Synthese von Nucleinsäuremolekülen
GB9806253D0 (en) *	1998-03-25	1998-05-20	Tepnel Medical Ltd	Amplification of nucleic acids
US6066458A (en) *	1998-05-18	2000-05-23	Becton, Dickinson And Company	Methods, apparatus and computer program products for determining quantities of nucleic acid sequences in samples using standard curves and amplification ratio estimates
US7087148B1 (en)	1998-06-23	2006-08-08	Clinical Micro Sensors, Inc.	Binding acceleration techniques for the detection of analytes
EP1098996A1 (de)	1998-07-20	2001-05-16	Yale University	Verfahren zum nachweis von nukleinsäuren unter verwendung zielgerichteter ligation von zweiteiligen primern
US6180408B1 (en)	1998-08-21	2001-01-30	Washington University	Fluorescence polarization in nucleic acid analysis
US7270958B2 (en)	1998-09-10	2007-09-18	The Regents Of The University Of Michigan	Compositions and methods for analysis of nucleic acids
CA2342838A1 (en) *	1998-09-15	2000-03-23	Yale University	Molecular cloning using rolling circle amplification
WO2000015849A1 (en)	1998-09-15	2000-03-23	Yale University	Artificial long terminal repeat vectors
KR20000025029A (ko) *	1998-10-07	2000-05-06	박한오	제한효소 절편의 배열화된 증폭의 전개방법
GB9822777D0 (en)	1998-10-20	1998-12-16	Tepnel Medical Ltd	Template chain reaction
US6410278B1 (en) *	1998-11-09	2002-06-25	Eiken Kagaku Kabushiki Kaisha	Process for synthesizing nucleic acid
EP1829856A3 (de)	1998-11-12	2009-02-25	Invitrogen Corporation	Transfektionsreagenzien
US6630333B1 (en) *	1999-03-23	2003-10-07	Invitrogen Corporation	Substantially pure reverse transriptases and methods of production thereof
US6309833B1 (en)	1999-04-12	2001-10-30	Nanogen/Becton Dickinson Partnership	Multiplex amplification and separation of nucleic acid sequences on a bioelectronic microchip using asymmetric structures
US6531302B1 (en)	1999-04-12	2003-03-11	Nanogen/Becton Dickinson Partnership	Anchored strand displacement amplification on an electronically addressable microchip
US6238868B1 (en) *	1999-04-12	2001-05-29	Nanogen/Becton Dickinson Partnership	Multiplex amplification and separation of nucleic acid sequences using ligation-dependant strand displacement amplification and bioelectronic chip technology
CA2369016A1 (en) *	1999-04-12	2000-10-19	Nanogen/Becton Dickinson Partnership	Amplification and separation of nucleic acid sequences using strand displacement amplification and bioelectronic microchip technology
US6326173B1 (en) *	1999-04-12	2001-12-04	Nanogen/Becton Dickinson Partnership	Electronically mediated nucleic acid amplification in NASBA
US20060275782A1 (en)	1999-04-20	2006-12-07	Illumina, Inc.	Detection of nucleic acid reactions on bead arrays
US20030215821A1 (en) *	1999-04-20	2003-11-20	Kevin Gunderson	Detection of nucleic acid reactions on bead arrays
CA2370976C (en)	1999-04-20	2009-10-20	Illumina, Inc.	Detection of nucleic acid reactions on bead arrays
WO2000066780A2 (en) *	1999-04-30	2000-11-09	University Of Florida	Adeno-associated virus-delivered ribozyme compositions and methods of use
EP1175501A4 (de) *	1999-05-12	2002-11-27	Invitrogen Corp	Zusammensetzungen und verfahren zur erhöhung der empfindlichkeit und spezifität der nukleinsäuresynthese
US8080380B2 (en)	1999-05-21	2011-12-20	Illumina, Inc.	Use of microfluidic systems in the detection of target analytes using microsphere arrays
JP2003500070A (ja) *	1999-05-21	2003-01-07	インビトロゲン・コーポレーション	核酸分子を標識するための組成物および方法
US8481268B2 (en)	1999-05-21	2013-07-09	Illumina, Inc.	Use of microfluidic systems in the detection of target analytes using microsphere arrays
US6316200B1 (en)	2000-06-08	2001-11-13	Becton, Dickinson And Company	Probes and methods for detection of nucleic acids
US20020025519A1 (en) *	1999-06-17	2002-02-28	David J. Wright	Methods and oligonucleotides for detecting nucleic acid sequence variations
US20030165913A1 (en) *	1999-06-17	2003-09-04	Sha-Sha Wang	Methods for detecting nucleic acid sequence variations
JP2003510017A (ja)	1999-06-22	2003-03-18	インビトロジェンコーポレイション	核酸の検出および識別のために改良されたプライマーおよび方法
US6830902B1 (en)	1999-07-02	2004-12-14	Invitrogen Corporation	Compositions and methods for enhanced sensitivity and specificity of nucleic acid synthesis
DK1238100T3 (da)	1999-07-23	2006-01-23	Gen Probe Inc	Polynucleotid-amplifikationsfremgangsmåde
ATE417127T1 (de)	1999-07-26	2008-12-15	Clinical Micro Sensors Inc	Nukelinsäuresequenzbestimmung mittels elektronischem nachweis
JP2003527087A (ja)	1999-08-13	2003-09-16	イェール・ユニバーシティ	バイナリーコード化配列タグ
US6472156B1 (en)	1999-08-30	2002-10-29	The University Of Utah	Homogeneous multiplex hybridization analysis by color and Tm
US6692918B2 (en) *	1999-09-13	2004-02-17	Nugen Technologies, Inc.	Methods and compositions for linear isothermal amplification of polynucleotide sequences
US6379888B1 (en)	1999-09-27	2002-04-30	Becton, Dickinson And Company	Universal probes and methods for detection of nucleic acids
AU767490B2 (en) *	1999-11-12	2003-11-13	Isis Pharmaceuticals, Inc.	Method for quantitating oligonucleotides
US6875619B2 (en)	1999-11-12	2005-04-05	Motorola, Inc.	Microfluidic devices comprising biochannels
US6361958B1 (en) *	1999-11-12	2002-03-26	Motorola, Inc.	Biochannel assay for hybridization with biomaterial
CN1757724B (zh)	1999-12-10	2014-06-11	茵维特罗根公司	具有独特特异性的多个重组位点在重组克隆中的用途
US7955794B2 (en)	2000-09-21	2011-06-07	Illumina, Inc.	Multiplex nucleic acid reactions
US7582420B2 (en)	2001-07-12	2009-09-01	Illumina, Inc.	Multiplex nucleic acid reactions
US8076063B2 (en)	2000-02-07	2011-12-13	Illumina, Inc.	Multiplexed methylation detection methods
EP2253717B1 (de) *	2000-04-07	2014-04-30	Eiken Kagaku Kabushiki Kaisha	Methode zur Amplifizierung von Nukleinsäuren mit Hilfe von dopplesträngigen Nukleinsäuren als Templat
US6291187B1 (en)	2000-05-12	2001-09-18	Molecular Staging, Inc.	Poly-primed amplification of nucleic acid sequences
US7078208B2 (en)	2000-05-26	2006-07-18	Invitrogen Corporation	Thermostable reverse transcriptases and uses thereof
CN1430670A (zh)	2000-05-26	2003-07-16	茵维特罗根公司	热稳定逆转录酶及其用途
US6191267B1 (en) *	2000-06-02	2001-02-20	New England Biolabs, Inc.	Cloning and producing the N.BstNBI nicking endonuclease
US6605451B1 (en)	2000-06-06	2003-08-12	Xtrana, Inc.	Methods and devices for multiplexing amplification reactions
EP2351853A1 (de)	2000-06-06	2011-08-03	Life Technologies Corporation	Methode und Vorrichtungen für multiplex Amplifizierungsreaktionen
US7087414B2 (en)	2000-06-06	2006-08-08	Applera Corporation	Methods and devices for multiplexing amplification reactions
US6602400B1 (en)	2000-06-15	2003-08-05	Motorola, Inc.	Method for enhanced bio-conjugation events
US7846733B2 (en)	2000-06-26	2010-12-07	Nugen Technologies, Inc.	Methods and compositions for transcription-based nucleic acid amplification
ATE455186T1 (de)	2000-06-26	2010-01-15	Nugen Technologies Inc	Methoden und zusammensetzungen zur auf transkription basierenden vervielfältigung von nukleinsäuren
US6323009B1 (en)	2000-06-28	2001-11-27	Molecular Staging, Inc.	Multiply-primed amplification of nucleic acid sequences
US6686157B2 (en)	2000-06-30	2004-02-03	Molecular Staging Inc.	Signal amplification with lollipop probes
WO2002010190A2 (en) *	2000-07-29	2002-02-07	Genaissance Pharmaceuticals, Inc.	Haplotypes of the il12b gene
ATE386821T1 (de)	2000-10-23	2008-03-15	Gen Probe Inc	Zusammensetzungen und methoden zur detektion von humanem immundefizienz virus 2 (hiv-2)
EP1366192B8 (de)	2000-10-24	2008-10-29	The Board of Trustees of the Leland Stanford Junior University	Direkte multiplex charakterisierung von genomischer dna
IE20000887A1 (en) *	2000-11-03	2002-12-11	Univ College Cork Nat Univ Ie	Method for the amplification and optional characterisation of nucleic acids
AR031640A1 (es) *	2000-12-08	2003-09-24	Applied Research Systems	Amplificacion isotermica de acidos nucleicos en un soporte solido
JP4394878B2 (ja)	2000-12-08	2010-01-06	ライフテクノロジーズコーポレーション	複数の認識部位を用いた核酸分子合成のための方法および組成物
WO2002048402A2 (en)	2000-12-13	2002-06-20	Nugen Technologies, Inc.	Methods and compositions for generation of multiple copies of nucleic acid sequences and methods of detection thereof
EP1347060A4 (de) *	2000-12-26	2004-08-18	Takara Bio Inc	Verfahren zum nachweis pathogener mikroorganismen
JPWO2002062993A1 (ja) *	2001-02-06	2004-06-10	タカラバイオ株式会社	増幅核酸及びその固定化物
JP3681729B2 (ja) *	2001-02-15	2005-08-10	タカラバイオ株式会社	塩基置換の検出方法
US6573051B2 (en)	2001-03-09	2003-06-03	Molecular Staging, Inc.	Open circle probes with intramolecular stem structures
ATE457200T1 (de)	2001-03-09	2010-02-15	Gen Probe Inc	Durchlässige haube
CA2439074A1 (en)	2001-03-09	2002-09-19	Nugen Technologies, Inc.	Methods and compositions for amplification of rna sequences
KR20030082535A (ko)	2001-03-09	2003-10-22	뉴젠 테크놀로지스 인코포레이티드	Ｒｎａ 서열의 증폭을 위한 방법 및 조성물
US20030092157A1 (en) *	2001-03-16	2003-05-15	Hayden Michael R.	Compositions, screening systems and methods for modulating HDL cholesterol and triglyceride levels
CN1384203A (zh) *	2001-04-30	2002-12-11	香港科技创业股份有限公司	具有高度延伸专一性的dna低温循环延伸反应方法
US20050009101A1 (en) *	2001-05-17	2005-01-13	Motorola, Inc.	Microfluidic devices comprising biochannels
WO2002097123A2 (en) *	2001-05-25	2002-12-05	Xenon Genetics, Inc.	Diagnostic methods for cardiovascular disease, low hdl-cholesterol levels, and high triglyceride levels
CA2348042A1 (en)	2001-06-04	2002-12-04	Ann Huletsky	Sequences for detection and identification of methicillin-resistant staphylococcus aureus
US6887245B2 (en) *	2001-06-11	2005-05-03	Ge Medical Systems Global Technology Company, Llc	Surgical drill for use with a computer assisted surgery system
EA006679B1 (ru) *	2001-06-12	2006-02-24	Такара Био Инк.	Способ стабилизации реагента для амплификации или детекции нуклеиновой кислоты и способ хранения
AU2002345938A1 (en) *	2001-06-28	2003-03-03	Mountain View Pharmaceuticals, Inc.	Polymer stabilized proteinases
US9261460B2 (en) *	2002-03-12	2016-02-16	Enzo Life Sciences, Inc.	Real-time nucleic acid detection processes and compositions
CA2453527A1 (en)	2001-07-12	2003-01-23	Illumina, Inc.	Multiplex nucleic acid reactions
AU2002365212A1 (en) *	2001-07-15	2003-09-02	Keck Graduate Institute	Gene expression analysis using nicking agents
KR20040036900A (ko) *	2001-07-15	2004-05-03	켁크 그래주에이트 인스티튜트	닉킹제를 사용한 핵산 단편의 증폭
WO2003008624A2 (en)	2001-07-15	2003-01-30	Keck Graduate Institute	Nucleic acid amplification using nicking agents
TWI335938B (en) *	2001-08-15	2011-01-11		Rna replication and amplification
JPWO2003016569A1 (ja) *	2001-08-20	2004-12-02	タカラバイオ株式会社	核酸の増幅方法
US6902914B2 (en) *	2001-09-28	2005-06-07	Sigma-Aldrich, Co.	Recombinant DNA processes using a dNTP mixture containing modified nucleotides
US7297485B2 (en)	2001-10-15	2007-11-20	Qiagen Gmbh	Method for nucleic acid amplification that results in low amplification bias
US6617137B2 (en) *	2001-10-15	2003-09-09	Molecular Staging Inc.	Method of amplifying whole genomes without subjecting the genome to denaturing conditions
US20030165859A1 (en)	2001-10-23	2003-09-04	Invitrogen Corporation	Primers and methods for the detection and discrimination of nucleic acids
US6942972B2 (en)	2001-10-24	2005-09-13	Beckman Coulter, Inc.	Efficient synthesis of protein-oligonucleotide conjugates
US7553619B2 (en)	2002-02-08	2009-06-30	Qiagen Gmbh	Detection method using dissociated rolling circle amplification
WO2003071252A2 (en)	2002-02-15	2003-08-28	Exact Sciences Corporation	Methods for analysis of molecular events
US7399590B2 (en)	2002-02-21	2008-07-15	Asm Scientific, Inc.	Recombinase polymerase amplification
CA2476481C (en)	2002-02-21	2016-01-26	Asm Scientific, Inc.	Recombinase polymerase amplification
US8030000B2 (en)	2002-02-21	2011-10-04	Alere San Diego, Inc.	Recombinase polymerase amplification
US7112406B2 (en) *	2002-03-01	2006-09-26	Integrated Dna Technologies, Inc.	Polynomial amplification of nucleic acids
US7629152B2 (en) *	2002-03-01	2009-12-08	Integrated Dna Technologies, Inc.	Methods for amplifying polymeric nucleic acids
AU2003222269A1 (en)	2002-03-11	2003-09-29	Nugen Technologies, Inc.	Methods for generating double stranded dna comprising a 3' single stranded portion and uses of these complexes for recombination
US9353405B2 (en)	2002-03-12	2016-05-31	Enzo Life Sciences, Inc.	Optimized real time nucleic acid detection processes
US7166478B2 (en) *	2002-03-12	2007-01-23	Enzo Life Sciences, Inc., C/O Enzo Biochem, Inc.	Labeling reagents and labeled targets, target labeling processes and other processes for using same in nucleic acid determinations and analyses
US20030219754A1 (en) *	2002-05-23	2003-11-27	Oleksy Jerome E.	Fluorescence polarization detection of nucleic acids
AU2003253651C1 (en)	2002-06-14	2010-06-03	Gen-Probe Incorporated	Compositions and methods for detecting hepatitis B virus
US20040072217A1 (en) *	2002-06-17	2004-04-15	Affymetrix, Inc.	Methods of analysis of linkage disequilibrium
EP2325303B1 (de)	2002-09-13	2013-11-06	Life Technologies Corporation	Wärmestabile reverse Transkriptasen und Verwendungen davon
US7662594B2 (en) *	2002-09-20	2010-02-16	New England Biolabs, Inc.	Helicase-dependent amplification of RNA
JP2006500030A (ja) *	2002-09-20	2006-01-05	イェールユニバーシティ	リボスイッチ、その使用方法、ならびにリボスイッチとともに用いるための組成物
DE60324810D1 (de) *	2002-09-20	2009-01-02	New England Biolabs Inc	HELICASE-ABHuNGIGE AMPLIFIKATION VON NUKLEINSUREN
CA2957200C (en)	2002-10-16	2020-05-26	Gen-Probe Incorporated	Compositions and methods for detecting west nile virus
AU2003280603A1 (en) *	2002-10-29	2004-05-25	Kabushiki Kaisha Dnaform	Method of amplifying nucleic acid
JPWO2004046383A1 (ja) *	2002-11-15	2006-03-16	株式会社ビー・エム・エル	Ｄｎａ増幅法
US7597936B2 (en) *	2002-11-26	2009-10-06	University Of Utah Research Foundation	Method of producing a pigmented composite microporous material
JP4824312B2 (ja) *	2002-11-26	2011-11-30	ユニバーシティオブユタリサーチファンデーション	微小孔物質、被分析物の局在化及び定量の方法、並びに被分析物の局在化及び定量用物品
EP3000899A1 (de)	2002-12-04	2016-03-30	Applied Biosystems, LLC	Multiplexverstärkung von polynucleotiden
US7955795B2 (en) *	2003-06-06	2011-06-07	Qiagen Gmbh	Method of whole genome amplification with reduced artifact production
US9487823B2 (en)	2002-12-20	2016-11-08	Qiagen Gmbh	Nucleic acid amplification
JP4886298B2 (ja) *	2002-12-20	2012-02-29	キアゲンゲゼルシャフトミットベシュレンクテルハフツング	核酸増幅
US6977153B2 (en) *	2002-12-31	2005-12-20	Qiagen Gmbh	Rolling circle amplification of RNA
US6852494B2 (en) *	2003-01-10	2005-02-08	Linden Technologies, Inc.	Nucleic acid amplification
US6943768B2 (en)	2003-02-21	2005-09-13	Xtellus Inc.	Thermal control system for liquid crystal cell
US20060192960A1 (en) *	2003-03-24	2006-08-31	Rencs Erik V	Polarization detection
US8043834B2 (en)	2003-03-31	2011-10-25	Qiagen Gmbh	Universal reagents for rolling circle amplification and methods of use
US20040265870A1 (en) *	2003-04-09	2004-12-30	Invitrogen Corporation	Methods of synthesizing and labeling nucleic acid molecules
JP2006523465A (ja) *	2003-04-14	2006-10-19	ニューゲンテクノロジーズ，インコーポレイテッド	ランダムにプライミングされる複合プライマーを用いる大規模増幅
KR20040091462A (ko) *	2003-04-22	2004-10-28	(주)바이오니아	미생물의 품질 관리 방법
US7291488B2 (en)	2003-04-25	2007-11-06	Becton, Dickinson & Company	Detection of herpes simplex virus types 1 and 2 by nucleic acid amplification
ATE542917T1 (de)	2003-05-19	2012-02-15	Gen Probe Inc	Zusammensetzungen, verfahren und kits zur bestimmung des vorhandenseins von trichomonas vaginalis in einer testprobe
US20050181394A1 (en) *	2003-06-20	2005-08-18	Illumina, Inc.	Methods and compositions for whole genome amplification and genotyping
EP1636337A4 (de)	2003-06-20	2007-07-04	Illumina Inc	Verfahren und zusammensetzungen zur ganzgenomischen amplifikation und genotypisierung
US20040259100A1 (en)	2003-06-20	2004-12-23	Illumina, Inc.	Methods and compositions for whole genome amplification and genotyping
WO2005012487A2 (en) *	2003-08-01	2005-02-10	Invitrogen Corporation	Compositions and methods for preparing short rna molecules and other nucleic acids
CA2538082A1 (en) *	2003-09-12	2005-03-24	Becton, Dickinson And Company	Assay for sars coronavirus by amplification and detection of the replicase sequence
WO2005025408A2 (en) *	2003-09-12	2005-03-24	Becton, Dickinson And Company	Assay for sars coronavirus by amplification and detection of nucleocapsid rna sequence
JP2005110664A (ja) *	2003-09-16	2005-04-28	Nissui Pharm Co Ltd	核酸シグナルの増幅による標的ｄｎａの存在を検出する方法、及び免疫学的配位子の検出又は定量する方法
CN1890368A (zh)	2003-12-10	2007-01-03	宝生物工程株式会社	扩增核酸的方法
US7314714B2 (en) *	2003-12-19	2008-01-01	Affymetrix, Inc.	Method of oligonucleotide synthesis
CA2547750C (en)	2003-12-19	2014-04-08	Gen-Probe Incorporated	Compositions, methods and kits for detecting the nucleic acids of hiv-1 and hiv-2
TW200525026A (en)	2003-12-25	2005-08-01	Riken	Method of amplifying nucleic acid and method of detecting mutated nucleic acid using the same
US20050158710A1 (en) *	2004-01-16	2005-07-21	Shirley Tsang	Detection of enterovirus nucleic acid
EP1725680B1 (de) *	2004-02-04	2009-12-23	QIAGEN North American Holdings, Inc.	Zusammensetzungen auf dutp-basis zurverringerung der primeraggregatbildung während der nukleinsäureamplifikation
US7481997B1 (en)	2004-02-12	2009-01-27	Montana State University	Snow mountain virus genome sequence, virus-like particles and methods of use
JP2007525224A (ja) *	2004-02-28	2007-09-06	チャン−ニンジェイ．ワン	核酸複合体
EP2208797A3 (de)	2004-03-01	2010-11-24	Applied Biosystems, LLC	Verfahren, Zusammensetzungen und Kits für Polynukleotidamplifikation
CA2558266C (en)	2004-03-05	2017-10-17	Gen-Probe Incorporated	Reagents, methods and kits for use in deactivating nucleic acids
EP1574583A1 (de) *	2004-03-10	2005-09-14	Roche Diagnostics GmbH	Verfahren zur Isolierung von Bakterien aus biologischen Proben
US20050233332A1 (en) *	2004-04-14	2005-10-20	Collis Matthew P	Multiple fluorophore detector system
US7229800B2 (en) *	2004-04-16	2007-06-12	Becton, Dickinson And Company	Neisseria gonorrhoeae assay
US8044184B2 (en)	2004-04-26	2011-10-25	Wako Pure Chemical Industries, Ltd.	Probe and primer for tubercle bacillus detection, and method of detecting human tubercle bacillus therewith
CA2565450C (en)	2004-05-07	2018-03-06	Gyorgy Petrovics	Methods of diagnosing or treating prostate cancer using the erg gene, alone or in combination with other over or under expressed genes in prostate cancer
US7622296B2 (en)	2004-05-28	2009-11-24	Wafergen, Inc.	Apparatus and method for multiplex analysis
US20090269737A1 (en) *	2004-06-29	2009-10-29	Wallac Oy	Integrated non-homogeneous nucleic acid amplification and detection
US7776530B2 (en) *	2004-06-29	2010-08-17	Wallac Oy	Integrated nucleic acid analysis
US20090232771A1 (en)	2004-07-13	2009-09-17	Takeda Pharmaceutical Company Limited	Method of controlling cell functions
US20060040258A1 (en) *	2004-08-23	2006-02-23	Huiyan Guo	Water-soluble conjugates and methods of preparation
US7981607B2 (en)	2004-08-27	2011-07-19	Esoterix Genetic Laboratories LLC	Method for detecting recombinant event
US20060062531A1 (en) *	2004-09-17	2006-03-23	Stephen Turner	Fabrication of optical confinements
US7170050B2 (en)	2004-09-17	2007-01-30	Pacific Biosciences Of California, Inc.	Apparatus and methods for optical analysis of molecules
US20060068430A1 (en) *	2004-09-20	2006-03-30	Sigma-Aldrich Co.	Purification of biomolecules from contaminating intact nucleic acids
ES2759991T3 (es)	2004-09-30	2020-05-12	Gen Probe Inc	Ensayo para detectar y cuantificar el VIH-1
EP1645640B1 (de)	2004-10-05	2013-08-21	Affymetrix, Inc.	Verfahren zur Detektion von chromosomalen Translokationen
DE102004049532A1 (de) *	2004-10-09	2006-04-13	Fischer, Achim, Dr.	Sequenzierung von Nukleinsäuren über Strand Displacement
US8158388B2 (en) *	2004-10-21	2012-04-17	New England Biolabs, Inc.	Repair of nucleic acids for improved amplification
US7700283B2 (en) *	2004-10-21	2010-04-20	New England Biolabs, Inc.	Repair of nucleic acids for improved amplification
CN101068932B (zh)	2004-10-27	2013-02-13	塞弗德公司	封闭系统多阶段核酸扩增反应
US9109256B2 (en)	2004-10-27	2015-08-18	Esoterix Genetic Laboratories, Llc	Method for monitoring disease progression or recurrence
CA2582661C (en) *	2004-11-09	2015-08-11	Gen-Probe Incorporated	Compositions and methods for detecting group a streptococci
WO2006063355A2 (en) *	2004-12-11	2006-06-15	Cytogenix , Inc.	Cell free biosynthesis of high-quality nucleic acid and uses thereof
RU2411290C2 (ru) *	2005-01-07	2011-02-10	Де Рейтер Сидз Р Энд Д Б.В.	Новый вирус растений
US9505846B2 (en)	2005-01-28	2016-11-29	Life Technologies Corporation	Multi-component inhibitors of nucleic acid polymerases
US20060177859A1 (en) *	2005-02-07	2006-08-10	Gen-Probe Incorporated	Compositions and methods for detecting group B streptococci
US20090124993A1 (en)	2005-02-17	2009-05-14	Burkly Linda C	Treating neurological disorders
CA2597319C (en)	2005-02-18	2014-09-30	Gen-Probe Incorporated	Sample preparation method incorporating an alkaline shock
US7824890B2 (en)	2005-02-19	2010-11-02	Avacta Group Plc	Isothermal amplification of nucleic acids
JP4398886B2 (ja) *	2005-03-07	2010-01-13	ソニー株式会社	通信端末装置、通信システム、通信方法、およびプログラム
CA2842402C (en)	2005-03-10	2016-02-23	Gen-Probe Incorporated	Systems and methods to perform assays for detecting or quantifying analytes within samples
EP1909108B1 (de)	2005-03-10	2019-05-29	Gen-Probe Incorporated	Systeme und Verfahren zur Durchführung von Tests zum Nachweis oder zur Quantifizierung von Analyten
EP1700922B1 (de)	2005-03-10	2016-08-24	Roche Diagnostics GmbH	3-Substituierte 5-Nitroindolderivate und diese enthaltende markierte Oligonukleotidsonden
US7759469B2 (en)	2005-03-10	2010-07-20	Roche Diagnostics Operations, Inc.	Labeling reagent
US20060205090A1 (en) *	2005-03-14	2006-09-14	Newton Michael W	Water-soluble conjugates for electrochemical detection
ES2440953T3 (es)	2005-03-31	2014-01-31	The General Hospital Corporation	Modulación de la actividad de HGF/HGFR para tratar un linfedema
US8309303B2 (en)	2005-04-01	2012-11-13	Qiagen Gmbh	Reverse transcription and amplification of RNA with simultaneous degradation of DNA
US7989166B2 (en)	2005-04-12	2011-08-02	In Situ Rcp A/S	Circle probes and their use in the identification of biomolecules
WO2006108423A2 (en)	2005-04-12	2006-10-19	In Situ Rcp A/S Under Founding	Methods for production of oligonucleotides
WO2007044071A2 (en)	2005-04-21	2007-04-19	Exact Sciences Corporation	Analysis of heterogeneous nucleic acid samples
KR101381331B1 (ko)	2005-05-09	2014-04-04	테라노스, 인코포레이티드	현장진료 유체 시스템 및 그 용도
US8242249B2 (en)	2005-05-13	2012-08-14	Wako Pure Chemical Industries, Ltd.	Primer and probe for use in detection of Mycobacterium kansasii and method for detection of Mycobacterium kansasii using the same
EP1883707B1 (de)	2005-05-26	2014-04-09	Human Genetic Signatures PTY Ltd	Isothermische strangverdrängungsamplifikation unter verwendung von eine nichtreguläre base enthaltenden primern
EP1929049B1 (de)	2005-07-25	2013-04-10	Alere San Diego, Inc.	Verfahren zur multiplexierung einer rekombinase-polymerase-verstärkung
US7939258B2 (en)	2005-09-07	2011-05-10	Nugen Technologies, Inc.	Nucleic acid amplification procedure using RNA and DNA composite primers
EP1762627A1 (de)	2005-09-09	2007-03-14	Qiagen GmbH	Verfahren zur Aktivierung einer Nukleinsäure für eine Polymerase-Reaktion
US9957569B2 (en) *	2005-09-12	2018-05-01	The Regents Of The University Of Michigan	Recurrent gene fusions in prostate cancer
JP5512125B2 (ja)	2005-09-12	2014-06-04	ザリージェンツオブザユニバーシティオブミシガン	前立腺癌における再発性遺伝子融合
JP2009511019A (ja) *	2005-10-06	2009-03-19	ルシジェンコーポレイション	耐熱性ウィルス性ポリメラーゼ及びその使用法
US11834720B2 (en)	2005-10-11	2023-12-05	Geneohm Sciences, Inc.	Sequences for detection and identification of methicillin-resistant Staphylococcus aureus (MRSA) of MREJ types xi to xx
JP5237817B2 (ja)	2005-10-21	2013-07-17	ジーンニュースインコーポレーティッド	バイオマーカー産物レベルを疾患に相関させるための方法および装置
CA2627490A1 (en)	2005-11-07	2007-05-18	Siemens Healthcare Diagnostics Inc.	Chlamydia trachomatis specific oligonucleotide sequences
JP5071987B2 (ja)	2005-11-14	2012-11-14	ジェン−プロウブインコーポレイテッド	パラメトリック較正方法
US20120021930A1 (en)	2005-11-22	2012-01-26	Stichting Dienst Landbouwkundig Onderzoek	Multiplex Nucleic Acid Detection
EP1798292A1 (de)	2005-12-19	2007-06-20	Nutreco Nederland B.V.	Verfahren zur Verbesserung der Truthanfleischproduktion
EP1974052A2 (de) *	2005-12-21	2008-10-01	Yale University	Verfahren und zusammensetzungen in verbindung mit der modulation von riboschaltern
US7981606B2 (en) *	2005-12-21	2011-07-19	Roche Molecular Systems, Inc.	Control for nucleic acid testing
US20080057499A1 (en) *	2006-02-06	2008-03-06	Affymetrix, Inc.	Methods for high specificity whole genome amplification and hybridization
US20090176878A1 (en) *	2007-10-05	2009-07-09	Washington University In St. Louis	Genetic polymorphisms and substance dependence
US20110143344A1 (en) *	2006-03-01	2011-06-16	The Washington University	Genetic polymorphisms and substance dependence
CN101400806A (zh)	2006-03-13	2009-04-01	和光纯药工业株式会社	突变基因的检测方法
JP5254949B2 (ja)	2006-03-15	2013-08-07	マイクロニクス，インコーポレイテッド	一体型の核酸アッセイ
EP2021503A1 (de) *	2006-03-17	2009-02-11	Solexa Ltd.	Isothermische methoden zur entstehung von arrays von einzelnen molekülen
US11287421B2 (en)	2006-03-24	2022-03-29	Labrador Diagnostics Llc	Systems and methods of sample processing and fluid control in a fluidic system
US8741230B2 (en)	2006-03-24	2014-06-03	Theranos, Inc.	Systems and methods of sample processing and fluid control in a fluidic system
MX2008012642A (es)	2006-04-07	2008-10-13	Siemens Healthcare Diagnostics	Secuencias oligonucleotido especificas para neisseria gonorrhoeae.
JP5654749B2 (ja) *	2006-04-11	2015-01-14	ニユー・イングランド・バイオレイブス・インコーポレイテツド	改良された増幅のための核酸の修復
US8900828B2 (en)	2006-05-01	2014-12-02	Cepheid	Methods and apparatus for sequential amplification reactions
US8188256B2 (en)	2006-05-02	2012-05-29	Wako Pure Chemical Industries, Ltd.	Primer and probe for detection of Mycobacterium intracellulare
JP2009535053A (ja)	2006-05-04	2009-10-01	エーエスエムサイエンティフィック，インコーポレイテッド	レコンビナーゼポリメラーゼ増幅
US8007999B2 (en)	2006-05-10	2011-08-30	Theranos, Inc.	Real-time detection of influenza virus
US7897747B2 (en) *	2006-05-25	2011-03-01	The Board Of Trustees Of The Leland Stanford Junior University	Method to produce single stranded DNA of defined length and sequence and DNA probes produced thereby
US20080125333A1 (en) *	2006-05-31	2008-05-29	Antara Biosciences Inc.	Devices and kits for detecting one or more target agents
US11001881B2 (en)	2006-08-24	2021-05-11	California Institute Of Technology	Methods for detecting analytes
WO2007146154A1 (en)	2006-06-06	2007-12-21	Gen-Probe Incorporated	Tagged oligonucleotides and their use in nucleic acid amplification methods
US8119352B2 (en) *	2006-06-20	2012-02-21	Cepheld	Multi-stage amplification reactions by control of sequence replication times
WO2008002920A2 (en) *	2006-06-26	2008-01-03	Epoch Biosciences, Inc.	Methods for generating target nucleic acid sequences
EP1878803A1 (de) *	2006-07-10	2008-01-16	Wageningen Universiteit	Verfahren zur Detektion von Wurzelgallen-Nematoden
US20080026394A1 (en) *	2006-07-11	2008-01-31	Antara Biosciences Inc.	Methods of detecting one or more cancer markers
EP2049262A2 (de)	2006-07-19	2009-04-22	Bionanomatrix, Inc.	Nanodüsen-geräteanordnungen: ihre herstellung und verwendung zur makromolekularen analyse
US7501254B2 (en) *	2006-07-20	2009-03-10	Ghc Technologies, Inc.	Methods and compositions for amplification and capture of nucleic acid sequences
NZ548731A (en) *	2006-07-24	2008-12-24	Zygem Corp Ltd	Isothermal detection methods and uses thereof
JP4918409B2 (ja)	2006-07-26	2012-04-18	西川ゴム工業株式会社	核酸配列の増幅方法
US11525156B2 (en)	2006-07-28	2022-12-13	California Institute Of Technology	Multiplex Q-PCR arrays
US8048626B2 (en)	2006-07-28	2011-11-01	California Institute Of Technology	Multiplex Q-PCR arrays
JP5244103B2 (ja)	2006-08-09	2013-07-24	ホームステッドクリニカルコーポレイション	器官特異的蛋白質およびその使用方法
US20080096257A1 (en) *	2006-08-15	2008-04-24	Zuxu Yao	Methods for Rapid, Single-Step Strand Displacement Amplification of Nucleic Acids
US11560588B2 (en)	2006-08-24	2023-01-24	California Institute Of Technology	Multiplex Q-PCR arrays
WO2008033866A2 (en) *	2006-09-11	2008-03-20	Yale University	Methods and compositions for the use of lysine riboswitches
EP1897891A1 (de)	2006-09-11	2008-03-12	Institut National De La Sante Et De La Recherche Medicale (Inserm)	Diagnose von hereditärer spastischer Paraplegie (HSP) durch Nachweis einer Mutation im KIAA1840 Gen oder Protein
US20080076123A1 (en) *	2006-09-27	2008-03-27	Helicos Biosciences Corporation	Polymerase variants for DNA sequencing
EP1914303A1 (de) *	2006-10-09	2008-04-23	Qiagen GmbH	Thermus eggertssonii DNA Polymerasen
US8012744B2 (en)	2006-10-13	2011-09-06	Theranos, Inc.	Reducing optical interference in a fluidic device
US8338109B2 (en)	2006-11-02	2012-12-25	Mayo Foundation For Medical Education And Research	Predicting cancer outcome
US20080113391A1 (en)	2006-11-14	2008-05-15	Ian Gibbons	Detection and quantification of analytes in bodily fluids
US7492312B2 (en) *	2006-11-14	2009-02-17	Fam Adly T	Multiplicative mismatched filters for optimum range sidelobe suppression in barker code reception
EP2479273A3 (de)	2006-12-18	2012-10-10	Wako Pure Chemical Industries, Ltd.	Primer und Sonde zur Erkennung von Mykobakterium Avium und Verfahren zur Erkennung von Mykobakterium Avium damit
EP1939303A1 (de) *	2006-12-27	2008-07-02	Wageningen Universiteit	Verfahren zur Erkennung von Zystennematoden
GB0701253D0 (en) *	2007-01-23	2007-02-28	Diagnostics For The Real World	Nucleic acid amplification and testing
CA2673748C (en)	2007-01-29	2016-08-16	Scientific Institute Of Public Health (Iph)	Transgenic plant event detection
NL1033431C2 (nl)	2007-02-20	2008-08-21	Expressive Res Bv	Bepaling van kwaliteitskenmerken bij land- of tuinbouwproducten.
EP1970440A1 (de) *	2007-03-06	2008-09-17	Qiagen GmbH	Polymerasestabilisierung durch ionische Reinigungsmittel
US8153064B2 (en)	2007-03-22	2012-04-10	Doebler Ii Robert W	Systems and devices for isothermal biochemical reactions and/or analysis
CA2964611C (en)	2007-03-28	2021-06-01	Bionano Genomics, Inc.	Methods of macromolecular analysis using nanochannel arrays
EP1978111B1 (de)	2007-04-02	2013-03-27	Gen-Probe Incorporated	Zusammensetzungen, Kits und zugehörige Verfahren zur Erkennung und/oder Überwachung von Pseudomonas aeruginosa
HUE030719T2 (en)	2007-04-09	2017-05-29	Univ Florida	Raav vector compositions having tyrosine-modified capsid proteins and methods for use
JP2008289483A (ja) *	2007-05-25	2008-12-04	Symphogen As	真核生物系において発現可能な形質転換体のスクリーニング
WO2008156987A2 (en) *	2007-05-29	2008-12-24	Yale University	Riboswitches and methods and compositions for use of and with riboswitches
WO2008150884A1 (en) *	2007-05-29	2008-12-11	Yale University	Methods and compositions related to riboswitches that control alternative splicing and rna processing
JP5282088B2 (ja)	2007-06-21	2013-09-04	ジェン−プロウブインコーポレイテッド	処理実行に使用する機器および容器
ES2376509T3 (es)	2007-07-06	2012-03-14	The Regents Of The University Of Michigan	Reordenamientos de genes mipol 1-etv1.
CA2814246A1 (en)	2007-07-06	2009-01-15	The Regents Of The University Of Michigan	Solute carrier family 45 member 3 (slc45a3) and erg family gene fusions in prostate cancer
US9689031B2 (en)	2007-07-14	2017-06-27	Ionian Technologies, Inc.	Nicking and extension amplification reaction for the exponential amplification of nucleic acids
US8143006B2 (en) *	2007-08-03	2012-03-27	Igor Kutyavin	Accelerated cascade amplification (ACA) of nucleic acids comprising strand and sequence specific DNA nicking
US8158430B1 (en)	2007-08-06	2012-04-17	Theranos, Inc.	Systems and methods of fluidic sample processing
ES2453108T3 (es)	2007-08-06	2014-04-04	Orion Genomics, Llc	Nuevos polimorfismos de un único nucleótido y combinaciones de polimorfismos nuevos y conocidos para determinar la expresión específica de alelo del gen IGF2
CA2639416C (en)	2007-09-11	2019-12-31	F. Hoffmann-La Roche Ag	Diagnostic test for susceptibility to b-raf kinase inhibitors
US9388457B2 (en)	2007-09-14	2016-07-12	Affymetrix, Inc.	Locus specific amplification using array probes
US8716190B2 (en)	2007-09-14	2014-05-06	Affymetrix, Inc.	Amplification and analysis of selected targets on solid supports
WO2009046094A1 (en)	2007-10-01	2009-04-09	Nabsys, Inc.	Biopolymer sequencing by hybridization of probes to form ternary complexes and variable range alignment
US8088593B2 (en)	2007-10-02	2012-01-03	Theranos, Inc.	Modular point-of-care devices, systems, and uses thereof
WO2009049268A1 (en)	2007-10-12	2009-04-16	Rheonix, Inc.	Integrated microfluidic device and methods
US20100324154A1 (en)	2007-11-01	2010-12-23	Hageman Gregory S	Assessing susceptibility to vascular disorders
EP2205617A4 (de) *	2007-11-06	2013-10-16	Siemens Healthcare Diagnostics	Hepatitis-b-virus-spezifische oligonukleotidsequenzen
US8911946B2 (en)	2007-12-21	2014-12-16	Gen-Probe Incorporated	Detection of antibiotic-resistant microorganisms
US20110020819A1 (en) *	2008-01-08	2011-01-27	Zygem Corporation Limited	Isothermal detection methods and uses thereof
EP2232259B1 (de)	2008-01-09	2016-10-12	Keck Graduate Institute	System, vorrichtung und verfahren zur materialvorbereitung und/oder -handhabung
JPWO2009099037A1 (ja)	2008-02-08	2011-05-26	和光純薬工業株式会社	クラミドフィラ・キャビエ検出用プライマー及びプローブ、並びにこれを用いたクラミドフィラ・キャビエの検出方法
US8034568B2 (en)	2008-02-12	2011-10-11	Nugen Technologies, Inc.	Isothermal nucleic acid amplification methods and compositions
US20090215050A1 (en) *	2008-02-22	2009-08-27	Robert Delmar Jenison	Systems and methods for point-of-care amplification and detection of polynucleotides
US20090227463A1 (en) *	2008-03-04	2009-09-10	Reif John H	Autonomous in vitro evolution
CA2718905A1 (en)	2008-03-17	2009-09-24	Expressive Research B.V.	Expression-linked gene discovery
GB2470672B (en)	2008-03-21	2012-09-12	Nugen Technologies Inc	Methods of RNA amplification in the presence of DNA
CA2719247C (en) *	2008-03-25	2017-03-21	The Regents Of The University Of Michigan	Ikki inhibitor therapies and screening methods, and related ikki diagnostics
EP3269824A1 (de)	2008-03-28	2018-01-17	Pacific Biosciences Of California, Inc.	Zusammensetzungen und verfahren zur nukleinsäuresequenzierung
EP3957754B1 (de)	2008-04-21	2026-01-28	Gen-Probe Incorporated	Verfahren zur erkennung des chikungunya-virus
EP2113574A1 (de)	2008-04-28	2009-11-04	Biotype AG	Stoffe und Verfahren für Profilierungstest auf DNA-Basis
WO2009140374A2 (en)	2008-05-13	2009-11-19	Gen-Probe Incorporated	Inactivatable target capture oligomers for use in the selective hybridization and capture of target nucleic acid sequences
WO2009145181A1 (ja)	2008-05-28	2009-12-03	和光純薬工業株式会社	マイコバクテリウム・イントラセルラー検出用プライマー及びプローブ、並びにこれを用いたマイコバクテリウム・イントラセルラーの検出方法
CA2725978A1 (en)	2008-05-28	2009-12-03	Genomedx Biosciences, Inc.	Systems and methods for expression-based discrimination of distinct clinical disease states in prostate cancer
US10407731B2 (en)	2008-05-30	2019-09-10	Mayo Foundation For Medical Education And Research	Biomarker panels for predicting prostate cancer outcomes
EP2297358A2 (de)	2008-05-30	2011-03-23	Gen-Probe Incorporated	Zusammensetzungen, kits und damit verbundene verfahren zum nachweis und/oder zur überwachung von salmonellen
CA3062190C (en)	2008-06-30	2023-03-28	Bionano Genomics, Inc.	Methods and devices for single-molecule whole genome analysis
US20110177509A1 (en) *	2008-07-23	2011-07-21	The Washington University	Risk factors and a therapeutic target for neurodegenerative disorders
US8882980B2 (en)	2008-09-03	2014-11-11	Nabsys, Inc.	Use of longitudinally displaced nanoscale electrodes for voltage sensing of biomolecules and other analytes in fluidic channels
US8262879B2 (en)	2008-09-03	2012-09-11	Nabsys, Inc.	Devices and methods for determining the length of biopolymers and distances between probes bound thereto
US9650668B2 (en)	2008-09-03	2017-05-16	Nabsys 2.0 Llc	Use of longitudinally displaced nanoscale electrodes for voltage sensing of biomolecules and other analytes in fluidic channels
US20110171649A1 (en) *	2008-09-10	2011-07-14	Igor Kutyavin	Detection of nucleic acids by oligonucleotide probes cleaved in presence of endonuclease v
US8383345B2 (en)	2008-09-12	2013-02-26	University Of Washington	Sequence tag directed subassembly of short sequencing reads into long sequencing reads
EP2331703A2 (de) *	2008-09-12	2011-06-15	Promega Corporation	Beurteilen der expression endogener und exogener gene
US9090948B2 (en)	2008-09-30	2015-07-28	Abbott Molecular Inc.	Primers and probes for detecting human papillomavirus and human beta globin sequences in test samples
CA2739462A1 (en) *	2008-10-31	2010-05-06	Abbott Laboratories	Methods for assembling panels of cancer cell lines for use in testing the efficacy of one or more pharmaceutical compositions
US9495515B1 (en)	2009-12-09	2016-11-15	Veracyte, Inc.	Algorithms for disease diagnostics
US10236078B2 (en)	2008-11-17	2019-03-19	Veracyte, Inc.	Methods for processing or analyzing a sample of thyroid tissue
AU2009316628B2 (en)	2008-11-18	2016-06-16	Bionano Genomics, Inc.	Polynucleotide mapping and sequencing
WO2010068102A1 (en)	2008-12-10	2010-06-17	Monsanto Invest N.V.	Novel plant virus
WO2010071431A1 (en)	2008-12-19	2010-06-24	Monsanto Invest N.V.	Method of breeding cysdv-resistant cucumber plants
US8748133B2 (en)	2008-12-30	2014-06-10	Gen-Probe Incorporated	Compositions, kits and related methods for the detection and/or monitoring of Listeria
EP2382328A2 (de)	2009-01-09	2011-11-02	The Regents of the University of Michigan	Rezidivierende genfusionen bei krebs
CA2750900C (en)	2009-01-30	2017-03-28	Gen-Probe Incorporated	Systems and methods for detecting a signal and applying thermal energy to a signal transmission element
US8685648B2 (en)	2009-02-03	2014-04-01	Biohelix Corporation	Endonuclease-enhanced helicase-dependent amplification
EP2396429B1 (de)	2009-02-11	2015-05-27	Orion Genomics, LLC	Kombinationen aus polymorphismen zur bestimmung von allelspezifischer igf2-expression
US20120094288A1 (en)	2009-02-17	2012-04-19	Murdoch Childrens Research Institute	Assay for determining epigenetic profiles of markers of fragile x alleles
US9074258B2 (en)	2009-03-04	2015-07-07	Genomedx Biosciences Inc.	Compositions and methods for classifying thyroid nodule disease
WO2010108926A1 (en)	2009-03-24	2010-09-30	Inserm (Institut National De La Sante Et De La Recherche Medicale)	Method for diagnosing or predicting a non syndromic autosomal recessive optic atrophy, or a risk of a non syndromic autosomal recessive optic atrophy.
US9393564B2 (en)	2009-03-30	2016-07-19	Ibis Biosciences, Inc.	Bioagent detection systems, devices, and methods
US8669057B2 (en)	2009-05-07	2014-03-11	Veracyte, Inc.	Methods and compositions for diagnosis of thyroid conditions
US9469867B2 (en)	2009-05-20	2016-10-18	Alere San Diego, Inc.	DNA glycosylase/lyase and AP endonuclease substrates
EP3360974B1 (de)	2009-06-05	2025-04-09	Abbott Diagnostics Scarborough, Inc.	Reagentien zur rekombinase polymerase amplifikation
JP5711227B2 (ja)	2009-06-26	2015-04-30	クレアモントバイオソリューソンズエルエルシー	試料破壊用ビーズを利用した生物検体の捕捉および溶出
EP2272980A1 (de)	2009-07-09	2011-01-12	Bioesplora SRL	Molekulare Sonden zum Nachweis und zur Quantifizierung von Target-Nukleinsäure
EP2789693B1 (de)	2009-08-13	2017-10-04	Life Technologies Corporation	Amelogenin-SNP auf X-Chromosomen
WO2011026139A1 (en)	2009-08-31	2011-03-03	Gen-Probe Incorporated	Dengue virus assay
EP2294912A1 (de)	2009-09-04	2011-03-16	Wageningen Universiteit	Verfahren zur Erhöhung des Zeaxanthinniveaus in einer Pflanzenlinie, Verfahren zur Auswahl einer Pflanze oder eines Teils davon, einschließlich eines Samens und einer Knolle, sowie Verwendung davon
WO2011034906A2 (en) *	2009-09-17	2011-03-24	The Regents Of The University Of Michigan	Recurrent gene fusions in prostate cancer
EP2483425B1 (de)	2009-09-28	2016-08-24	Igor Kutyavin	Verfahren und zusammensetzung zur nukleinsäureerkennung auf basis stabilisierter oligonukleotidsondenkomplexe
EP2483424B1 (de)	2009-10-02	2013-12-04	INSERM - Institut National de la Santé et de la Recherche Médicale	Verfahren zur diagnose/prognose von altersbedingter makuladegeneration
EP2488668B1 (de)	2009-10-15	2023-07-26	Life Technologies Corporation	Neue menschliche einzelnukleotid-polymorphismen
US8951733B2 (en)	2009-10-16	2015-02-10	Monsanto Technology Llc	Methods of polynucleotide detection
CN105808956A (zh)	2009-10-19	2016-07-27	提拉诺斯公司	集成的健康数据采集和分析系统
WO2011049439A1 (en)	2009-10-19	2011-04-28	Universiteit Twente	Method for selecting bone forming mesenchymal stem cells
CN102648295B (zh)	2009-12-07	2017-08-08	伊鲁米那股份有限公司	用于多重基因分型的多样品索引
US9121054B2 (en) *	2009-12-08	2015-09-01	Biohelix Corporation	Detection of nucleic acid amplification products in the presence of an internal control sequence on an immunochromatographic strip
US10446272B2 (en)	2009-12-09	2019-10-15	Veracyte, Inc.	Methods and compositions for classification of samples
US20110165568A1 (en)	2009-12-31	2011-07-07	Life Technologies Corporation	Sequences of e.coli 055:h7 genome
EP2531515B1 (de)	2010-01-22	2015-10-21	Gen-Probe Incorporated	Sonden zur erkennung des vorhandenseins von trichomonas vaginalis in einer probe
US9132423B2 (en)	2010-01-29	2015-09-15	Micronics, Inc.	Sample-to-answer microfluidic cartridge
WO2011095475A1 (en)	2010-02-02	2011-08-11	INSERM (Institut National de la Santé et de la Recherche Médicale)	Methods for the diagnosis and therapy of retinitis pigmentosa
CN102918155B (zh)	2010-03-23	2015-12-16	和光纯药工业株式会社	沙眼衣原体检测用引物和探针、以及使用该引物和探针的沙眼衣原体的检测方法
US10787701B2 (en)	2010-04-05	2020-09-29	Prognosys Biosciences, Inc.	Spatially encoded biological assays
US20190300945A1 (en)	2010-04-05	2019-10-03	Prognosys Biosciences, Inc.	Spatially Encoded Biological Assays
AU2011237729B2 (en)	2010-04-05	2014-04-03	Prognosys Biosciences, Inc.	Spatially encoded biological assays
US8383793B2 (en)	2010-04-15	2013-02-26	St. Jude Children's Research Hospital	Methods and compositions for the diagnosis and treatment of cancer resistant to anaplastic lymphoma kinase (ALK) kinase inhibitors
WO2011128096A1 (en)	2010-04-16	2011-10-20	Roche Diagnostics Gmbh	Polymorphism markers for predicting response to interleukin-6 receptor-inhibiting monoclonal antibody drug treatment
AU2011248625B2 (en)	2010-04-26	2017-01-05	Pangu Biopharma Limited	Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of cysteinyl-tRNA synthetase
JP6294074B2 (ja)	2010-04-27	2018-03-14	エータイアーファーマ，インコーポレイテッド	イソロイシルｔＲＮＡ合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見
JP5454338B2 (ja)	2010-04-28	2014-03-26	株式会社島津製作所	液滴操作によるリアルタイム核酸増幅法
CN103097524B (zh)	2010-04-28	2016-08-03	Atyr医药公司	与丙氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现
AU2011248457B2 (en)	2010-04-29	2017-02-16	Pangu Biopharma Limited	Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of valyl tRNA synthetases
CA2797374C (en)	2010-04-29	2021-02-16	Pangu Biopharma Limited	Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of asparaginyl trna synthetases
WO2011150279A2 (en)	2010-05-27	2011-12-01	Atyr Pharma, Inc.	Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glutaminyl-trna synthetases
WO2011140135A2 (en)	2010-05-03	2011-11-10	Atyr Pharma, Inc.	Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of methionyl-trna synthetases
WO2011139986A2 (en)	2010-05-03	2011-11-10	Atyr Pharma, Inc.	Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of arginyl-trna synthetases
CA2797977C (en)	2010-05-03	2019-08-20	Atyr Pharma, Inc.	Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-alpha-trna synthetases
CA2798139C (en)	2010-05-04	2019-09-24	Atyr Pharma, Inc.	Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of p38 multi-trna synthetase complex
WO2011137533A1 (en)	2010-05-05	2011-11-10	The Governing Council Of The University Of Toronto	Method of processing dried samples using digital microfluidic device
CN103200953B (zh)	2010-05-14	2017-02-15	Atyr 医药公司	与苯丙氨酰‑β‑tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现
CA2800281C (en)	2010-06-01	2021-01-12	Atyr Pharma, Inc.	Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of lysyl-trna synthetases
CA2801468C (en)	2010-06-04	2018-09-04	Chronix Biomedical	Prostate cancer associated circulating nucleic acid biomarkers
WO2011162612A1 (en)	2010-06-25	2011-12-29	Wageningen Universiteit	Method for modulating the level of phosphorylation of starch in a plant line, method for selecting a plant or part thereof, including a seed and tuber, and use thereof
EP2588629B1 (de)	2010-06-30	2017-05-17	Gen-Probe Incorporated	Methode und apparatur zur identifizierung von analyt-beinhaltenden proben unter verwendung von single-read determination des analyten und prozesskontrollsignalen
BR112013000433A2 (pt)	2010-07-07	2016-05-17	Univ Michigan	diagnóstico e tratamento de câncer de mama
AU2011289831C1 (en)	2010-07-12	2017-06-15	Pangu Biopharma Limited	Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glycyl-tRNA synthetases
SG187101A1 (en)	2010-07-16	2013-02-28	Stichting Vu Vumc	A method of analysing a blood sample of a subject for the presence of a disease marker
WO2012018639A2 (en)	2010-07-26	2012-02-09	Biomatrica, Inc.	Compositions for stabilizing dna, rna and proteins in saliva and other biological samples during shipping and storage at ambient temperatures
WO2012018638A2 (en)	2010-07-26	2012-02-09	Biomatrica, Inc.	Compositions for stabilizing dna, rna and proteins in blood and other biological samples during shipping and storage at ambient temperatures
US20130210007A1 (en)	2010-08-11	2013-08-15	Murdoch Childrens Research Institute	Treatment and diagnosis of epigenetic disorders and conditions
WO2012020102A1 (en)	2010-08-12	2012-02-16	Inserm (Institut National De La Sante Et De La Recherche Medicale)	Methods and kits for of identifying a premature infant at risk of having or developing bronchopulmonary dysplasia
US12043866B2 (en)	2010-08-13	2024-07-23	Envirologix Inc.	Compositions and methods for quantifying a nucleic acid sequence in a sample
EP2420579A1 (de) *	2010-08-17	2012-02-22	QIAGEN GmbH	Helikasenabhängige isothermale Amplifikation mit Nicking-Enzymen
CN103108650A (zh)	2010-08-25	2013-05-15	Atyr医药公司	与酪氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现
EP2937423A1 (de)	2010-09-21	2015-10-28	Life Technologies Corporation	Se33-mutationen mit auswirkung auf die genotypkonkordanz
WO2012040619A2 (en)	2010-09-24	2012-03-29	Massachusetts Eye And Ear Infirmary	Methods and compositions for prognosing and/or detecting age-related macular degeneration
US8715933B2 (en) *	2010-09-27	2014-05-06	Nabsys, Inc.	Assay methods using nicking endonucleases
CA2814532C (en)	2010-10-12	2021-07-27	Monsanto Technology Llc	Soybean plant and seed corresponding to transgenic event mon87712 and methods for detection thereof
WO2012049279A1 (en)	2010-10-14	2012-04-19	Universitaet Des Saarlandes	MEANS AND METHODS APPLYING SINGLE NUCLEOTIDE PRIMER EXTENSION WITH ION PAIR-, REVERSED-PHASE HPLC (SIRPH) FOR THE DIAGNOSIS OF SNPs
US20150218639A1 (en)	2014-01-17	2015-08-06	Northwestern University	Biomarkers predictive of predisposition to depression and response to treatment
US10093981B2 (en)	2010-10-19	2018-10-09	Northwestern University	Compositions and methods for identifying depressive disorders
US20150225792A1 (en)	2014-01-17	2015-08-13	Northwestern University	Compositions and methods for identifying depressive disorders
US10233501B2 (en)	2010-10-19	2019-03-19	Northwestern University	Biomarkers predictive of predisposition to depression and response to treatment
US8563298B2 (en)	2010-10-22	2013-10-22	T2 Biosystems, Inc.	NMR systems and methods for the rapid detection of analytes
CA2815085C (en)	2010-10-22	2022-06-21	T2 Biosystems, Inc.	Nmr systems and methods for the rapid detection of analytes
CN103282511A (zh)	2010-11-01	2013-09-04	贝克顿·迪金森公司	阴道加特纳菌测定
US9074251B2 (en)	2011-02-10	2015-07-07	Illumina, Inc.	Linking sequence reads using paired code tags
EP2640849B1 (de)	2010-11-16	2016-04-06	Nabsys 2.0 LLC	Verfahren zur sequenzierung von biomolekülen durch nachweis der relativen positionen von hybridisierten sonden
US8945556B2 (en)	2010-11-19	2015-02-03	The Regents Of The University Of Michigan	RAF gene fusions
CA3012765A1 (en)	2010-11-19	2012-05-24	The Regents Of The University Of Michigan	Ncrna and uses thereof
US20130267443A1 (en)	2010-11-19	2013-10-10	The Regents Of The University Of Michigan	ncRNA AND USES THEREOF
WO2012077819A1 (ja)	2010-12-10	2012-06-14	国立大学法人東京工業大学	標的核酸の検出方法及びキット
CN103269787B9 (zh)	2010-12-21	2016-07-20	株式会社岛津制作所	用于在管内操作对象成分的器件和方法
CN106323875B (zh)	2011-01-21	2019-07-09	西拉诺斯知识产权有限责任公司	样品使用最大化的系统和方法
WO2012106546A2 (en)	2011-02-02	2012-08-09	University Of Washington Through Its Center For Commercialization	Massively parallel continguity mapping
WO2012109574A2 (en)	2011-02-11	2012-08-16	Nabsys, Inc.	Assay methods using dna binding proteins
ES2659763T3 (es)	2011-02-14	2018-03-19	The Regents Of The University Of Michigan	Composiciones y procedimientos para el tratamiento de obesidad y trastornos relacionados
NL2006378C2 (en)	2011-03-11	2012-09-12	Univ Wageningen	Tyclv resistance.
AU2012231884B2 (en)	2011-03-18	2017-03-09	Stichting Vumc	A method of analysing a blood sample of a subject for the presence of a disease marker
GB201106254D0 (en)	2011-04-13	2011-05-25	Frisen Jonas	Method and product
EP2697657B8 (de)	2011-04-15	2017-08-16	Becton, Dickinson and Company	Mikrofluidischer abtastender echtzeit-thermocycler und verfahren zur optischen detektion mittels synchronisierter thermozyklierung und abtastung
WO2012165943A1 (en)	2011-05-27	2012-12-06	Vereniging Voor Christelijk Hoger Onderwijs, Wetenschappelijk Onderzoek En Patiëntenzorg	A method of analysing a blood sample of a subject for the presence of an infectious disease marker
WO2012169887A2 (en)	2011-06-06	2012-12-13	Stichting Katholieke Universiteit, More Particularly The Radboud University Nijmegen Medical Centre	Use of new markers in a diagnostic assay for determining severity of rsv infection
US20120322676A1 (en)	2011-06-17	2012-12-20	Life Technologies Corporation	Compositions and methods for detection of cronobacter spp. and cronobacter species and strains
WO2013002354A1 (ja)	2011-06-29	2013-01-03	株式会社ダナフォーム	生体試料の前処理方法、ｒｎａの検出方法及び前処理キット
EP2726618A1 (de)	2011-06-30	2014-05-07	Monsanto Technology LLC	Alfalfa-pflanze und samen im zusammenhang mit dem transgenen ereignis kk 179-2 sowie verfahren zu ihrem nachweis
EP2742150A1 (de)	2011-08-09	2014-06-18	Vereniging voor Christelijk Hoger Onderwijs, Wetenschappelijk Onderzoek en Patiëntenzorg	Verfahren zur analyse einer blutprobe einer person auf fetale erkrankungs-oder zustandsmarker
EP2748332B1 (de)	2011-08-24	2018-06-13	Oxoid Limited	Zusammensetzungen und verfahren zum nachweis mehrerer mikroorganismen
RU2014110271A (ru)	2011-08-31	2015-10-10	Ф. Хоффманн-Ля Рош Аг	Восприимчивость к ингибиторам ангиогенеза
CN103946395A (zh)	2011-08-31	2014-07-23	霍夫曼-拉罗奇有限公司	用于预测与抗血管发生疗法有关的高血压的风险的方法
US10752944B2 (en)	2011-09-06	2020-08-25	Gen-Probe Incorporated	Circularized templates for sequencing
EP2753712B1 (de)	2011-09-06	2017-03-22	Gen-Probe Incorporated	Geschlossene nukleinsäurestrukturen
WO2013034645A1 (en)	2011-09-06	2013-03-14	INSERM (Institut National de la Santé et de la Recherche Médicale)	Methods and kits for predicting the risk of having a melanoma in a subject
EP2746395B1 (de)	2011-09-08	2017-11-29	Kabushiki Kaisha DNAFORM	Primer-set, verfahren zur amplifizierung einer nukleinsäuresequenz damit und verfahren zur erkennung von mutierter nukleinsäure damit
US9632102B2 (en)	2011-09-25	2017-04-25	Theranos, Inc.	Systems and methods for multi-purpose analysis
US9619627B2 (en)	2011-09-25	2017-04-11	Theranos, Inc.	Systems and methods for collecting and transmitting assay results
US9268915B2 (en)	2011-09-25	2016-02-23	Theranos, Inc.	Systems and methods for diagnosis or treatment
US8435738B2 (en)	2011-09-25	2013-05-07	Theranos, Inc.	Systems and methods for multi-analysis
US8380541B1 (en)	2011-09-25	2013-02-19	Theranos, Inc.	Systems and methods for collecting and transmitting assay results
US8475739B2 (en)	2011-09-25	2013-07-02	Theranos, Inc.	Systems and methods for fluid handling
US8840838B2 (en)	2011-09-25	2014-09-23	Theranos, Inc.	Centrifuge configurations
US9664702B2 (en)	2011-09-25	2017-05-30	Theranos, Inc.	Fluid handling apparatus and configurations
US20140170735A1 (en)	2011-09-25	2014-06-19	Elizabeth A. Holmes	Systems and methods for multi-analysis
WO2013043715A1 (en)	2011-09-19	2013-03-28	Genentech, Inc.	Combination treatments comprising c-met antagonists and b-raf antagonists
WO2013044097A1 (en)	2011-09-21	2013-03-28	Gen-Probe Incorporated	Methods for amplifying nucleic acid using tag-mediated displacement
US9352312B2 (en)	2011-09-23	2016-05-31	Alere Switzerland Gmbh	System and apparatus for reactions
US10012664B2 (en)	2011-09-25	2018-07-03	Theranos Ip Company, Llc	Systems and methods for fluid and component handling
US9810704B2 (en)	2013-02-18	2017-11-07	Theranos, Inc.	Systems and methods for multi-analysis
MX344792B (es)	2011-09-25	2017-01-06	Theranos Inc	Sistemas y métodos para múltiples análisis.
US9250229B2 (en)	2011-09-25	2016-02-02	Theranos, Inc.	Systems and methods for multi-analysis
US9416153B2 (en)	2011-10-11	2016-08-16	Enzo Life Sciences, Inc.	Fluorescent dyes
EP2768985B1 (de)	2011-10-21	2019-03-20	Chronix Biomedical	Mit kolorektalkarzinom assoziierte zirkulierende nukleinsäurebiomarker
JP6085564B2 (ja)	2011-10-31	2017-02-22	栄研化学株式会社	標的核酸の検出法
WO2013067413A1 (en)	2011-11-04	2013-05-10	Gen-Probe Incorporated	Molecular assay reagents and methods
JP2014533100A (ja)	2011-11-04	2014-12-11	オスロウニヴェルスィテーツスィーケフースハーエフＯｓｌｏＵｎｉｖｅｒｓｉｔｅｔｓｓｙｋｅｈｕｓＨｆ	結腸直腸癌の分析のための方法およびバイオマーカー
WO2013071233A1 (en)	2011-11-10	2013-05-16	The United States Of America, As Represented By The Secretary, Department Of Health & Human Services	Methods for detecting infectious agents and a novel virus detected thereby
JP2014533956A (ja)	2011-11-23	2014-12-18	エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト	血管新生阻害剤に対する応答性
US10513737B2 (en)	2011-12-13	2019-12-24	Decipher Biosciences, Inc.	Cancer diagnostics using non-coding transcripts
JP6093498B2 (ja)	2011-12-13	2017-03-08	株式会社日立ハイテクノロジーズ	核酸増幅方法
US20130189679A1 (en)	2011-12-20	2013-07-25	The Regents Of The University Of Michigan	Pseudogenes and uses thereof
WO2013096838A2 (en)	2011-12-22	2013-06-27	Ibis Biosciences, Inc.	Systems and methods for isolating nucleic acids
US9115394B2 (en)	2011-12-22	2015-08-25	Roche Molecular Systems, Inc.	Methods and reagents for reducing non-specific amplification
JP5807542B2 (ja)	2011-12-22	2015-11-10	株式会社島津製作所	対象成分を操作するためのチップデバイス及びそれを用いた方法
US9334491B2 (en)	2011-12-22	2016-05-10	Ibis Biosciences, Inc.	Systems and methods for isolating nucleic acids from cellular samples
WO2013101935A1 (en)	2011-12-27	2013-07-04	Ibis Biosciences, Inc.	Bioagent detection oligonucleotides
EP2802673B1 (de)	2012-01-09	2019-07-03	Oslo Universitetssykehus HF	Verfahren und biomarker zur analyse von kolorektalkarzinomen
IN2014MN01642A (de)	2012-02-16	2015-07-03	Atyr Pharma Inc
US9506117B2 (en)	2012-02-21	2016-11-29	Oslo Universitetssykehus Hf	Methods and biomarkers for detection and prognosis of cervical cancer
AU2013229151A1 (en)	2012-03-06	2014-09-25	Aarhus University	Gene signatures associated with efficacy of postmastectomy radiotherapy in breast cancer
ES2948896T3 (es)	2012-03-29	2023-09-21	Becton Dickinson Co	Acidos nucleicos para la amplificación de ácidos nucleicos
EP2834369B1 (de)	2012-04-02	2018-05-30	Life Technologies Corporation	Zusammensetzungen und verfahren zur detektion von vogelmykobakterium-paratuberkulose
WO2013152114A1 (en)	2012-04-03	2013-10-10	The Regents Of The University Of Michigan	Biomarker associated with irritable bowel syndrome and crohn's disease
CN108424972B (zh)	2012-04-06	2021-11-05	基因欧姆科技加拿大公司	用于检测和鉴定MREJ型xxi的耐甲氧西林金黄色葡萄球菌(MRSA)的序列
KR102362649B1 (ko)	2012-04-09	2022-02-14	엔바이로로직스 인크.	시료 내 핵산 서열을 정량화하기 위한 조성물 및 방법
EP2836605A1 (de)	2012-04-11	2015-02-18	Institut National de la Santé et de la Recherche Médicale (INSERM)	Verfahren zur diagnose einer skeletalen ziliopathie
EP2836846B1 (de)	2012-04-13	2024-04-24	Becton, Dickinson and Company	Reflexprüfung von proben unter verwendung von restmaterialien aus einem vorhergehenden test
CN114214394A (zh)	2012-06-08	2022-03-22	爱奥尼安技术公司	核苷酸扩增反应
US9012022B2 (en)	2012-06-08	2015-04-21	Illumina, Inc.	Polymer coatings
US8895249B2 (en)	2012-06-15	2014-11-25	Illumina, Inc.	Kinetic exclusion amplification of nucleic acid libraries
US20140005061A1 (en)	2012-06-29	2014-01-02	Life Technologies Corporation	Compositions and methods for detection of multiple microorganisms
WO2014005076A2 (en)	2012-06-29	2014-01-03	The Regents Of The University Of Michigan	Methods and biomarkers for detection of kidney disorders
EP2867377B1 (de)	2012-07-02	2019-08-21	The Translational Genomics Research Institute	Primer, assays und verfahren zum nachweis eines e.-coli-subtyps
WO2014015217A1 (en)	2012-07-19	2014-01-23	Vertex Pharmaceuticals Incorporated	Biomarkers for hcv infected patients
EP3428290B1 (de)	2012-07-26	2022-04-06	Illumina, Inc.	Zusammensetzungen und verfahren zur amplifikation von nukleinsäuren
US9932628B2 (en)	2012-07-27	2018-04-03	Gen-Probe Incorporated	Dual reference calibration method and system for quantifying polynucleotides
AU2013202793B2 (en)	2012-07-31	2014-09-18	Gen-Probe Incorporated	System, method and apparatus for automated incubation
ES3015226T3 (en)	2012-08-16	2025-04-30	Veracyte Sd Inc	Prostate cancer prognosis using biomarkers
AU2013315800A1 (en)	2012-09-11	2015-03-12	Theranos Ip Company, Llc	Information management systems and methods using a biological signature
SG11201502189UA (en)	2012-09-23	2015-04-29	Univ Erasmus Medical Ct	Human betacoronavirus lineage c and identification of n-terminal dipeptidyl peptidase as its virus receptor
US9914968B2 (en)	2012-09-26	2018-03-13	Cepheid	Honeycomb tube
CA2886334C (en)	2012-09-28	2021-12-21	Bna Inc.	Bna clamp method
US9593365B2 (en)	2012-10-17	2017-03-14	Spatial Transcriptions Ab	Methods and product for optimising localised or spatial detection of gene expression in a tissue sample
EP2909341A2 (de)	2012-10-18	2015-08-26	Oslo Universitetssykehus HF	Biomarker für gebärmutterhalskrebs
US9181583B2 (en)	2012-10-23	2015-11-10	Illumina, Inc.	HLA typing using selective amplification and sequencing
MX367366B (es)	2012-11-27	2019-08-16	Univ Pontificia Catolica Chile	Composiciones y metodos para diagnosticar tumores de tiroides.
EP2740805B1 (de)	2012-12-07	2019-02-20	SuppreMol GmbH	Stratifizierung und Behandlung von Patienten, die an idiopathischer thrombozytopenischer Purpura leiden
US9914966B1 (en)	2012-12-20	2018-03-13	Nabsys 2.0 Llc	Apparatus and methods for analysis of biomolecules using high frequency alternating current excitation
EP3249054A1 (de)	2012-12-20	2017-11-29	Biomatrica, INC.	Formulierungen und verfahren zur stabilisierung von pcr-reagenzien
WO2014100743A2 (en)	2012-12-21	2014-06-26	Micronics, Inc.	Low elasticity films for microfluidic use
EP2935908B1 (de)	2012-12-21	2019-08-14	PerkinElmer Health Sciences, Inc.	Fluidkreisläufe und zugehörige herstellungsverfahren
EP2935559B1 (de)	2012-12-21	2020-09-16	PerkinElmer Health Sciences, Inc.	Fluoreszenznachweissystem
US9683230B2 (en)	2013-01-09	2017-06-20	Illumina Cambridge Limited	Sample preparation on a solid support
WO2014113557A1 (en)	2013-01-18	2014-07-24	Nabsys, Inc.	Enhanced probe binding
SG11201506421PA (en)	2013-02-18	2015-09-29	Theranos Inc	Systems and methods for collecting and transmitting assay results
US9512422B2 (en)	2013-02-26	2016-12-06	Illumina, Inc.	Gel patterned surfaces
US9623409B2 (en)	2013-03-11	2017-04-18	Cue Inc.	Cartridges, kits, and methods for enhanced mixing for detection and quantification of analytes
US10975423B2 (en)	2013-03-11	2021-04-13	Elitechgroup, Inc.	Methods for true isothermal strand displacement amplification
US10590474B2 (en)	2013-03-11	2020-03-17	Elitechgroup B.V.	Methods for true isothermal strand displacement amplification
WO2014164479A1 (en)	2013-03-11	2014-10-09	Elitech Holding B.V.	Methods for true isothermal strand displacement amplification
IL290168B2 (en)	2013-03-11	2023-03-01	Cue Health Inc	Systems and methods for the detection and measurement of analytes
US10545161B2 (en)	2013-03-11	2020-01-28	Cue Health Inc.	Systems and methods for detection and quantification of analytes
WO2014160233A1 (en)	2013-03-13	2014-10-02	Abbott Molecular Inc.	Systems and methods for isolating nucleic acids
US20160023208A1 (en)	2013-03-13	2016-01-28	Illumina, Inc.	Multilayer fluidic devices and methods for their fabrication
EP3553175B1 (de)	2013-03-13	2021-07-14	Illumina, Inc.	Verfahren zur herstellung von nukleinsäuresequenzierungsbibliotheken
EP2971115B1 (de)	2013-03-13	2022-07-27	Seegene, Inc.	Quantifizierung von zielnukleinsäuren unter verwendung von schmelzspitzenwertanalyse
JP2016512437A (ja)	2013-03-14	2016-04-28	アボツト・モレキユラー・インコーポレイテツド	多重メチル化特異的増幅システムおよび方法
AU2013202788B2 (en)	2013-03-14	2015-10-01	Gen-Probe Incorporated	Indexing signal detection module
ES2732012T3 (es)	2013-03-14	2019-11-20	Abbott Molecular Inc	Minimización de errores utilizando uracil-ADN-N-glicosilasa
AU2013202778A1 (en)	2013-03-14	2014-10-02	Gen-Probe Incorporated	Systems, methods, and apparatuses for performing automated reagent-based assays
CA2899645C (en)	2013-03-15	2022-08-30	Gen-Probe Incorporated	Calibration method, apparatus and computer program product
CN105358709B (zh)	2013-03-15	2018-12-07	雅培分子公司	用于检测基因组拷贝数变化的系统和方法
US11976329B2 (en)	2013-03-15	2024-05-07	Veracyte, Inc.	Methods and systems for detecting usual interstitial pneumonia
US9255265B2 (en)	2013-03-15	2016-02-09	Illumina, Inc.	Methods for producing stranded cDNA libraries
EP2971083B1 (de)	2013-03-15	2018-05-02	Becton, Dickinson and Company	Nachweis von neisseria gonorrhoeaes
US20160153029A1 (en)	2013-03-15	2016-06-02	Ibis Biosciences, Inc.	Dna sequences to assess contamination in dna sequencing
EP2992331A4 (de)	2013-04-30	2017-03-29	Université de Montréal	Neuartige biomarker für akute myeloische leukämie
US9365581B2 (en)	2013-05-02	2016-06-14	The Regents Of The University Of Michigan	Deuterated amlexanox
EP2994532B1 (de)	2013-05-07	2017-11-15	Micronics, Inc.	Verfahren zur herstellung von nukleinsäurehaltigen proben mittels tonmineralien und alkalischen lösungen
US10386377B2 (en)	2013-05-07	2019-08-20	Micronics, Inc.	Microfluidic devices and methods for performing serum separation and blood cross-matching
EP2994543B1 (de)	2013-05-07	2018-08-15	Micronics, Inc.	Vorrichtung zur herstellung und analyse von nukleinsäuren
GB201308313D0 (en)	2013-05-09	2013-06-19	Medical Res Council	Assay Method
US20160115541A1 (en)	2013-05-29	2016-04-28	Chronix Biomedical	Detection and quantification of donor cell-free dna in the circulation of organ transplant recipients
EP3004433B1 (de)	2013-05-30	2018-09-05	The Regents of The University of California	Im wesentlichen gleichmässige amplifizierung von genomen
DK3013983T3 (da)	2013-06-25	2023-03-06	Prognosys Biosciences Inc	Spatialt kodede biologiske assays ved brug af en mikrofluidisk anordning
MX363806B (es)	2013-07-01	2019-04-03	Illumina Inc	Funcionalización de superficies sin catalizador e injerto de polímeros..
US10392670B2 (en)	2013-07-25	2019-08-27	Dch Molecular Diagnostics, Inc.	Methods and compositions for detecting bacterial contamination
TWI707038B (zh)	2013-08-05	2020-10-11	美商扭轉生物科技有限公司	重新合成之基因庫
US11545241B1 (en)	2013-09-07	2023-01-03	Labrador Diagnostics Llc	Systems and methods for analyte testing and data management
EP3502127B1 (de)	2013-10-09	2023-07-26	Monsanto Technology LLC	Transgenes ereignis mon87403 in mais und nachweisverfahren dafür
CN105940024B (zh)	2013-12-05	2019-03-15	生捷科技控股公司	修饰的表面
WO2015085274A1 (en)	2013-12-05	2015-06-11	Centrillion Technology Holdings Corporation	Methods for sequencing nucleic acids
EP3077543B1 (de)	2013-12-05	2019-09-25	Centrillion Technology Holdings Corporation	Herstellung von gemusterten anordnungen
EP3080268A1 (de)	2013-12-09	2016-10-19	Illumina, Inc.	Verfahren und zusammensetzungen zur gezielten nukleinsäuresequenzierung
US11859246B2 (en)	2013-12-11	2024-01-02	Accuragen Holdings Limited	Methods and compositions for enrichment of amplification products
US11286519B2 (en)	2013-12-11	2022-03-29	Accuragen Holdings Limited	Methods and compositions for enrichment of amplification products
KR20240025725A (ko)	2013-12-11	2024-02-27	아큐라젠 홀딩스 리미티드	희귀 서열 변이를 검출하기 위한 조성물 및 방법
WO2015089438A1 (en)	2013-12-13	2015-06-18	Northwestern University	Biomarkers for post-traumatic stress states
US10246746B2 (en)	2013-12-20	2019-04-02	Illumina, Inc.	Preserving genomic connectivity information in fragmented genomic DNA samples
JP6739339B2 (ja)	2014-01-15	2020-08-12	アボット・ラボラトリーズＡｂｂｏｔｔＬａｂｏｒａｔｏｒｉｅｓ	カバーされた配列変換ｄｎａおよび検出方法
US9677132B2 (en)	2014-01-16	2017-06-13	Illumina, Inc.	Polynucleotide modification on solid support
WO2015108663A1 (en)	2014-01-16	2015-07-23	Illumina, Inc.	Amplicon preparation and sequencing on solid supports
US9663770B2 (en)	2014-01-22	2017-05-30	Life Technologies Corporation	Reverse transcriptases for use in high temperature nucleic acid synthesis
GB2559919B (en)	2014-02-28	2018-11-14	Gen Probe Inc	Method of isolating nucleic acid from specimens in liquid-based cytology preservatives containing formaldehyde
EP3670663B1 (de)	2014-02-28	2024-08-07	Gen-Probe Incorporated	Verfahren zur isolierung von nukleinsäure aus proben in flüssigkeitsbasierten zytologischen konservierungsmitteln mit formaldehyd
WO2015147370A1 (en)	2014-03-28	2015-10-01	Seegene, Inc.	Detection of target nucleic acid sequences using different detection temperatures
US11060139B2 (en)	2014-03-28	2021-07-13	Centrillion Technology Holdings Corporation	Methods for sequencing nucleic acids
DK3125936T3 (da)	2014-03-31	2019-08-05	Debiopharm Int Sa	Fgfr-fusioner
AU2015239394B2 (en)	2014-03-31	2017-11-02	Kabushiki Kaisha Dnaform	Fluorescent labeled single-stranded nucleic acid and use thereof
MX386087B (es)	2014-04-22	2025-03-18	Envirologix Inc	Composiciones y metodos para mejorar y/o predecir la amplificacion de adn.
USD745423S1 (en)	2014-05-12	2015-12-15	Cue Inc.	Automated analyzer test cartridge and sample collection device for analyte detection
US10760109B2 (en)	2014-06-06	2020-09-01	The Regents Of The University Of Michigan	Compositions and methods for characterizing and diagnosing periodontal disease
US20150353989A1 (en)	2014-06-09	2015-12-10	Illumina Cambridge Limited	Sample preparation for nucleic acid amplification
WO2015191632A1 (en)	2014-06-10	2015-12-17	Biomatrica, Inc.	Stabilization of thrombocytes at ambient temperatures
GB201410420D0 (en)	2014-06-11	2014-07-23	Illumina Cambridge Ltd	Methods for estimating cluster numbers
WO2015189636A1 (en)	2014-06-13	2015-12-17	Illumina Cambridge Limited	Methods and compositions for preparing sequencing libraries
WO2016003814A1 (en)	2014-06-30	2016-01-07	Illumina, Inc.	Methods and compositions using one-sided transposition
US12297505B2 (en)	2014-07-14	2025-05-13	Veracyte, Inc.	Algorithms for disease diagnostics
WO2016011203A1 (en)	2014-07-15	2016-01-21	Life Technologies Corporation	Compositions with lipid aggregates and methods for efficient delivery of molecules to cells
WO2016011280A1 (en)	2014-07-16	2016-01-21	Tangen Biosciences, Inc.	Isothermal methods for amplifying nucleic acid samples
EP3183577B1 (de)	2014-08-21	2020-08-19	Illumina Cambridge Limited	Reversible oberflächenfunktionalisierung
WO2016040602A1 (en)	2014-09-11	2016-03-17	Epicentre Technologies Corporation	Reduced representation bisulfite sequencing using uracil n-glycosylase (ung) and endonuclease iv
US20170247756A1 (en)	2014-10-03	2017-08-31	Life Technologies Corporation	Genetic sequence verification compositions, methods and kits
JP6773651B2 (ja)	2014-10-14	2020-10-21	アボット・ラボラトリーズＡｂｂｏｔｔＬａｂｏｒａｔｏｒｉｅｓ	ポリｄｎａスペーサー配列を有する配列変換およびシグナル増幅ｄｎａならびにそれらを用いた検出方法
JP6808617B2 (ja)	2014-10-17	2021-01-06	イルミナケンブリッジリミテッド	連続性を維持した転位
US10793922B2 (en)	2014-10-20	2020-10-06	Envirologix Inc.	Compositions and methods for detecting an RNA virus
US10570463B2 (en)	2014-10-29	2020-02-25	Biotium, Inc.	Nucleic acid modifying agents and uses thereof
CN114805710B (zh)	2014-10-31	2023-11-17	伊鲁米纳剑桥有限公司	聚合物以及dna共聚物涂层
US11559801B2 (en)	2014-11-03	2023-01-24	Tangen Biosciences, Inc.	Apparatus and method for cell, spore, or virus capture and disruption
CN114606309A (zh)	2014-11-05	2022-06-10	威拉赛特公司	使用机器学习和高维转录数据的诊断系统和方法
GB201419731D0 (en)	2014-11-05	2014-12-17	Illumina Cambridge Ltd	Sequencing from multiple primers to increase data rate and density
CN107109494B (zh)	2014-11-10	2023-10-27	豪夫迈·罗氏有限公司	Il-33介导型疾病的治疗方法和诊断方法
WO2016077426A1 (en)	2014-11-11	2016-05-19	Abbott Molecular Inc.	Hybridization probes and methods
WO2016118766A2 (en)	2015-01-21	2016-07-28	T2 Biosystems, Inc.	Nmr methods and systems for the rapid detection of tick-borne pathogens
WO2016126882A1 (en)	2015-02-04	2016-08-11	Twist Bioscience Corporation	Methods and devices for de novo oligonucleic acid assembly
WO2016126987A1 (en)	2015-02-04	2016-08-11	Twist Bioscience Corporation	Compositions and methods for synthetic gene assembly
US10208339B2 (en)	2015-02-19	2019-02-19	Takara Bio Usa, Inc.	Systems and methods for whole genome amplification
WO2016134342A1 (en)	2015-02-20	2016-08-25	Wafergen, Inc.	Method for rapid accurate dispensing, visualization and analysis of single cells
US9708647B2 (en)	2015-03-23	2017-07-18	Insilixa, Inc.	Multiplexed analysis of nucleic acid hybridization thermodynamics using integrated arrays
US20180100192A1 (en)	2015-03-31	2018-04-12	lllumina Cambridge Limited	Surface concatemerization of templates
CN120425026A (zh)	2015-04-10	2025-08-05	十程基因技术瑞典公司	生物样本的空间区别、多重核酸分析
US9981239B2 (en)	2015-04-21	2018-05-29	Twist Bioscience Corporation	Devices and methods for oligonucleic acid library synthesis
ES2961374T3 (es)	2015-04-24	2024-03-11	Atila Biosystems Incorporated	Amplificación con cebadores de composición de nucleótidos limitada
KR102786859B1 (ko)	2015-04-24	2025-03-26	벡톤 디킨슨 앤드 컴퍼니	외음질 칸디다증, 질편모충증 및 세균성 질염의 복합 검출 방법
JP2018518157A (ja)	2015-05-11	2018-07-12	イラミーナインコーポレーテッド	治療薬剤の発見および分析のためのプラットフォーム
JP6822974B2 (ja)	2015-05-29	2021-01-27	エフ．ホフマン−ラロシュアーゲーＦ．Ｈｏｆｆｍａｎｎ−ＬａＲｏｃｈｅＡｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ	シトラコン酸無水物によって微生物を不活性化する方法
WO2016196478A1 (en)	2015-06-01	2016-12-08	St. Jude Children's Research Hospital	Methods and compositions for prognostications and/or clinical management of graft-versus-host disease and transplant rejection
WO2016197103A1 (en)	2015-06-05	2016-12-08	Miroculus Inc.	Air-matrix digital microfluidics apparatuses and methods for limiting evaporation and surface fouling
EP3303548A4 (de)	2015-06-05	2019-01-02	Miroculus Inc.	Verdampfungsverwaltung in digitalen mikrofluidischen vorrichtungen
ES2955883T3 (es)	2015-06-19	2023-12-07	Sera Prognostics Inc	Pares de biomarcadores para la predicción del parto prematuro
CN107922966B (zh)	2015-07-06	2022-06-28	伊卢米纳剑桥有限公司	用于核酸扩增的样品制备
CN107924121B (zh)	2015-07-07	2021-06-08	亿明达股份有限公司	经由纳米压印的选择性表面图案化
WO2017015018A1 (en)	2015-07-17	2017-01-26	Illumina, Inc.	Polymer sheets for sequencing applications
BR112018000851B1 (pt)	2015-07-17	2022-10-18	Cue Health Inc	Cartucho de análise de amostras, placas de circuito para o mesmo e método de amplificação
EP3124619B1 (de)	2015-07-31	2019-03-06	Menicon Co., Ltd	Reagenzien, verfahren und kit zur glaukomdiagnose über hunderassen hinweg und innerhalb von hunderassen
EA201890512A1 (ru)	2015-08-17	2018-09-28	Кура Онколоджи, Инк.	Способы лечения пациентов со злокачественными опухолями с использованием ингибиторов фарнезилтрансферазы
CN107921432A (zh)	2015-09-02	2018-04-17	伊卢米纳剑桥有限公司	改善流控系统中的液滴操作的系统和方法
US9499861B1 (en)	2015-09-10	2016-11-22	Insilixa, Inc.	Methods and systems for multiplex quantitative nucleic acid amplification
KR20180050411A (ko)	2015-09-18	2018-05-14	트위스트 바이오사이언스 코포레이션	올리고핵산 변이체 라이브러리 및 그의 합성
CN108698012A (zh)	2015-09-22	2018-10-23	特韦斯特生物科学公司	用于核酸合成的柔性基底
MX2018004284A (es)	2015-10-09	2018-05-16	Accuragen Holdings Ltd	Metodos y composiciones para el enriquecimiento de productos de amplificacion.
EP3156497A1 (de)	2015-10-16	2017-04-19	Centre National de la Recherche Scientifique (C.N.R.S.)	Trpv2 als biomarker und als therapeutisches target für melanome
EP3373723B1 (de)	2015-11-10	2025-08-20	Vilmorin & Cie	Resistenz gegen tolcndv in kürbis
IL259466B (en)	2015-11-20	2022-09-01	Seegene Inc	Method for calibrating a data set of a target analyte
WO2017095958A1 (en)	2015-12-01	2017-06-08	Twist Bioscience Corporation	Functionalized surfaces and preparation thereof
EP3383994A4 (de)	2015-12-03	2019-08-28	Accuragen Holdings Limited	Verfahren und zusammensetzungen zum formen von ligationsprodukten
KR102589056B1 (ko)	2015-12-08	2023-10-12	바이오매트리카 인코포레이티드	적혈구 침강 속도의 감소
US11485998B2 (en)	2015-12-15	2022-11-01	Seegene, Inc.	Signal extraction for a target nucleic acid sequence
EP3181699A1 (de)	2015-12-17	2017-06-21	Oniris	Mikro-rnas als prädiktive biomarker von typ-1-diabetes
US20190032104A1 (en)	2016-01-21	2019-01-31	T2 Biosystems, Inc.	Rapid antimicrobial susceptibility testing using high-sensitivity direct detection methods
EP3407974A4 (de)	2016-01-29	2019-08-28	The Regents Of The University Of Michigan	Amlexanox-analoga
US10978173B2 (en)	2016-02-05	2021-04-13	Seegene, Inc.	Method for reducing noise level of data set for a target analyte
WO2017155858A1 (en)	2016-03-07	2017-09-14	Insilixa, Inc.	Nucleic acid sequence identification using solid-phase cyclic single base extension
PL3377226T3 (pl)	2016-03-28	2021-07-26	Illumina, Inc.	Wielopłaszczyznowe mikromacierze
WO2017180745A1 (en)	2016-04-14	2017-10-19	T2 Biosystems, Inc.	Methods and systems for amplification in complex samples
WO2017184968A1 (en)	2016-04-22	2017-10-26	Kura Oncology, Inc.	Methods of selecting cancer patients for treatment with farnesyltransferase inhibitors
CN109511265B (zh)	2016-05-16	2023-07-14	安可济控股有限公司	通过链鉴定改进测序的方法
SG11201809376WA (en)	2016-05-18	2018-12-28	Illumina Inc	Self assembled patterning using patterned hydrophobic surfaces
US11767566B2 (en)	2016-06-03	2023-09-26	Max-Planck-Gesellschaft	Methods for the detection of a latent tuberculosis infection
EP3475706B1 (de)	2016-06-27	2021-08-11	Juno Therapeutics, Inc.	Mhc-e-beschränkte epitopen, bindungsmoleküle, und zugehörige verfahren und verwendungen
US20200182884A1 (en)	2016-06-27	2020-06-11	Juno Therapeutics, Inc.	Method of identifying peptide epitopes, molecules that bind such epitopes and related uses
WO2018013509A1 (en)	2016-07-11	2018-01-18	Arizona Board Of Regents On Behalf Of The University Of Arizona	Compositions and methods for diagnosing and treating arrhythmias
US11460405B2 (en)	2016-07-21	2022-10-04	Takara Bio Usa, Inc.	Multi-Z imaging and dispensing with multi-well devices
KR102475710B1 (ko)	2016-07-22	2022-12-08	오레곤 헬스 앤드 사이언스 유니버시티	단일 세포 전체 게놈 라이브러리 및 이의 제조를 위한 조합 인덱싱 방법
WO2018035170A1 (en)	2016-08-15	2018-02-22	Accuragen Holdings Limited	Compositions and methods for detecting rare sequence variants
CA3034064A1 (en)	2016-08-22	2018-03-01	Miroculus Inc.	Feedback system for parallel droplet control in a digital microfluidic device
KR102212257B1 (ko)	2016-08-22	2021-02-04	트위스트 바이오사이언스 코포레이션	드 노보 합성된 핵산 라이브러리
US11414708B2 (en)	2016-08-24	2022-08-16	Decipher Biosciences, Inc.	Use of genomic signatures to predict responsiveness of patients with prostate cancer to post-operative radiation therapy
EP3287528A1 (de)	2016-08-25	2018-02-28	AGCT GmbH	Verfahren zur amplifikation von nukleinsäuren und kit zu dessen durchführung
WO2018057526A2 (en)	2016-09-21	2018-03-29	Twist Bioscience Corporation	Nucleic acid based data storage
EP3519554A4 (de)	2016-09-30	2020-05-20	The Governing Council Of The University Of Toronto	System zur identifizierung und zum targeting von zellen in einer heterogenen population zur selektiven extraktion von zellgehalt
RS61745B1 (sr)	2016-11-03	2021-05-31	Kura Oncology Inc	Inhibitori farneziltransferaze za upotrebu u tretiranju kancera
EP3554514A4 (de)	2016-12-16	2020-08-05	Twist Bioscience Corporation	Variante bibliotheken der immunologischen synapse und synthese davon
WO2018126082A1 (en)	2016-12-28	2018-07-05	Miroculis Inc.	Digital microfluidic devices and methods
GB201704754D0 (en)	2017-01-05	2017-05-10	Illumina Inc	Kinetic exclusion amplification of nucleic acid libraries
WO2018127786A1 (en)	2017-01-06	2018-07-12	Oslo Universitetssykehus Hf	Compositions and methods for determining a treatment course of action
AU2018210695B2 (en)	2017-01-20	2024-07-18	The University Of British Columbia	Molecular subtyping, prognosis, and treatment of bladder cancer
WO2018140540A1 (en)	2017-01-25	2018-08-02	Cue Health Inc.	Systems and methods for enhanced detection and quantification of analytes
US10137121B2 (en)	2017-02-21	2018-11-27	Kura Oncology, Inc.	Methods of treating cancer with farnesyltransferase inhibitors
KR102003179B1 (ko)	2017-02-21	2019-07-23	쿠라 온콜로지, 인크.	파르네실트랜스퍼라제 억제제를 사용하는 암 환자의 치료 방법
CN110892485B (zh)	2017-02-22	2024-03-22	特韦斯特生物科学公司	基于核酸的数据存储
WO2018165600A1 (en)	2017-03-09	2018-09-13	Genomedx Biosciences, Inc.	Subtyping prostate cancer to predict response to hormone therapy
AU2018234629A1 (en)	2017-03-15	2019-10-17	Twist Bioscience Corporation	Variant libraries of the immunological synapse and synthesis thereof
EP4219771A3 (de)	2017-03-24	2023-08-16	Gen-Probe Incorporated	Zusammensetzungen und verfahren für den multiplexnachweis viraler krankheitserreger in proben
KR102270849B1 (ko)	2017-03-28	2021-06-29	주식회사 씨젠	타겟 핵산 서열의 존재를 결정하기 위한 분석 시그널
WO2018187476A1 (en)	2017-04-04	2018-10-11	Miroculus Inc.	Digital microfluidic apparatuses and methods for manipulating and processing encapsulated droplets
US10737267B2 (en)	2017-04-04	2020-08-11	Omniome, Inc.	Fluidic apparatus and methods useful for chemical and biological reactions
ES2893528T3 (es)	2017-04-23	2022-02-09	Illumina Cambridge Ltd	Composiciones y métodos para mejorar la identificación de muestras en colecciones de ácidos nucleicos indexadas
AU2018259202B2 (en)	2017-04-23	2022-03-24	Illumina Cambridge Limited	Compositions and methods for improving sample identification in indexed nucleic acid libraries
ES2937929T3 (es)	2017-04-23	2023-04-03	Illumina Inc	Composiciones y métodos para mejorar la identificación de muestras en bibliotecas de ácido nucleico indexadas
US11078542B2 (en)	2017-05-12	2021-08-03	Decipher Biosciences, Inc.	Genetic signatures to predict prostate cancer metastasis and identify tumor aggressiveness
CA3064762A1 (en)	2017-05-24	2018-11-29	Northwestern University	Devices and methods for rapid sample processing and analysis
US10995104B2 (en)	2017-05-30	2021-05-04	Roche Molecular System, Inc.	Catalysts for reversing formaldehyde adducts and crosslinks
KR102628035B1 (ko)	2017-06-07	2024-01-22	오레곤 헬스 앤드 사이언스 유니버시티	메틸화 서열결정을 위한 단일 세포 전체 게놈 라이브러리
WO2018231864A1 (en)	2017-06-12	2018-12-20	Twist Bioscience Corporation	Methods for seamless nucleic acid assembly
JP7169999B2 (ja)	2017-06-12	2022-11-11	ツイストバイオサイエンスコーポレーション	シームレス核酸アセンブリのための方法
US11217329B1 (en)	2017-06-23	2022-01-04	Veracyte, Inc.	Methods and systems for determining biological sample integrity
EP3658908B1 (de)	2017-07-24	2025-11-12	Integra Biosciences AG	Digitale mikrofluidiksysteme und verfahren mit integrierter plasmasammelvorrichtung
EP3662482A1 (de)	2017-07-31	2020-06-10	Illumina Inc.	Sequenzierungssystem mit multiplexierter aggregation biologischer proben
FI3662083T3 (fi)	2017-08-01	2024-11-20	Illumina Inc	Geneettisen materiaalin ja kirjastovalmisteen spatiaalinen indeksointi hydrogeelihelmiä ja virtauskennoja käyttämällä
KR102480894B1 (ko)	2017-08-01	2022-12-23	일루미나, 인코포레이티드	뉴클레오티드 서열분석용 하이드로겔 비드
AU2018310987A1 (en)	2017-08-04	2020-02-27	Decipher Biosciences, Inc.	Use of immune cell-specific gene expression for prognosis of prostate cancer and prediction of responsiveness to radiation therapy
US10806730B2 (en)	2017-08-07	2020-10-20	Kura Oncology, Inc.	Methods of treating cancer with farnesyltransferase inhibitors
MX2020001207A (es)	2017-08-07	2020-03-20	Kura Oncology Inc	Metodos de tratamiento del cancer con inhibidores de farnesiltransferasa.
SG11202000964UA (en)	2017-08-15	2020-02-27	Omniome Inc	Scanning apparatus and methods useful for detection of chemical and biological analytes
AU2018317902B2 (en)	2017-08-18	2025-02-20	Sera Prognostics, Inc.	Pregnancy clock proteins for predicting due date and time to birth
EP3676009A4 (de)	2017-09-01	2021-06-16	Miroculus Inc.	Digitale mikrofluidikvorrichtungen und verfahren zu ihrer verwendung
AU2018328847A1 (en)	2017-09-11	2020-04-23	Twist Bioscience Corporation	GPCR binding proteins and synthesis thereof
ES2915413T3 (es)	2017-09-27	2022-06-22	Abbott Molecular Inc	Ensayo para la detección del virus de la hepatitis B (VHB)
ES3035799T3 (en)	2017-10-03	2025-09-09	Abbott Molecular Inc	Assay for detecting hepatitis c virus (hcv)
CA3068498A1 (en)	2017-10-03	2019-04-11	Abbott Molecular Inc.	Assay for detecting human immunodeficiency virus (hiv)
CA3079411C (en)	2017-10-19	2023-12-05	Omniome, Inc.	Simultaneous background reduction and complex stabilization in binding assay workflows
WO2019079769A1 (en)	2017-10-20	2019-04-25	Twist Bioscience Corporation	HEATED NANOWELLS FOR THE SYNTHESIS OF POLYNUCLEOTIDES
WO2019089982A1 (en)	2017-11-01	2019-05-09	Juno Therapeutics, Inc.	Method of assessing activity of recombinant antigen receptors
US11035010B2 (en)	2017-12-14	2021-06-15	Medicinal Genomics Corporation	Methods and kits for classifying cannabinoid production in cannabis plants
EP4715681A2 (de)	2018-01-04	2026-03-25	Atlas Data Storage, Inc.	Digitale informationsspeicherung auf dna-basis
WO2019139792A1 (en)	2018-01-09	2019-07-18	Abbott Molecular Inc.	Assay for detecting chlamydia trachomatis, neisseria gonorrhoeae, trichomonas vaginalis, and mycoplasma genitalium
IL276343B2 (en) *	2018-01-29	2024-10-01	St Jude Childrens Res Hospital Inc	Method for nucleic acid amplification
KR20230142806A (ko)	2018-02-09	2023-10-11	제넨테크, 인크.	비만 세포 매개 염증성 질환에 대한 치료 및 진단 방법
EP4253562A3 (de)	2018-02-13	2023-10-25	Illumina, Inc.	Dna-sequenzierung unter verwendung von hydrogelperlen
US11203782B2 (en)	2018-03-29	2021-12-21	Accuragen Holdings Limited	Compositions and methods comprising asymmetric barcoding
CN110832086A (zh)	2018-04-02	2020-02-21	伊鲁米那股份有限公司	用于制造用于基于序列的遗传检验的对照的组合物和方法
WO2019191900A1 (en)	2018-04-03	2019-10-10	Burning Rock Biotech	Compositions and methods for preparing nucleic acid libraries
WO2019202536A1 (en)	2018-04-18	2019-10-24	St. Jude Children's Research Hospital	Genotyping assays to identify mutations in xaf1
CA3097583A1 (en)	2018-04-19	2019-10-24	Omniome, Inc.	Improving accuracy of base calls in nucleic acid sequencing methods
SG11202009878VA (en)	2018-04-20	2020-11-27	Epigeneron Inc	Method for detecting variation of reference sequence in target nucleic acid region
AU2019257320B2 (en)	2018-04-20	2022-04-07	Illumina, Inc.	Methods of encapsulating single cells, the encapsulated cells and uses thereof
US12235273B2 (en)	2018-05-04	2025-02-25	Abbott Laboratories	HBV diagnostic, prognostic, and therapeutic methods and products
KR102640255B1 (ko)	2018-05-17	2024-02-27	일루미나, 인코포레이티드	감소된 증폭 편향을 갖는 고속-대량 단일 세포 서열분석
IL278771B2 (en)	2018-05-18	2025-09-01	Twist Bioscience Corp	Polynucleotides, reagents and methods for nucleic acid hybridization
CA3096855A1 (en)	2018-05-23	2019-11-28	Miroculus Inc.	Control of evaporation in digital microfluidics
KR102507415B1 (ko)	2018-06-04	2023-03-07	일루미나, 인코포레이티드	고속 대량 단일 세포 전사체 라이브러리 그리고 이의 제조 및 사용 방법
WO2019241290A1 (en)	2018-06-12	2019-12-19	Accuragen Holdings Limited	Methods and compositions for forming ligation products
CA3103268A1 (en)	2018-06-28	2020-01-02	Gen-Probe Incorporated	Sample preparation method and system
GB201812149D0 (en) *	2018-07-25	2018-09-05	Sense Biodetection Ltd	Nucleic acid detection method
AU2019319203B8 (en)	2018-08-08	2025-10-09	Gen-Probe Incorporated	Compositions, methods and kits for detecting Mycoplasma genitalium
AU2019321683B2 (en) *	2018-08-17	2025-04-03	Dana-Farber Cancer Institute, Inc.	DNA amplification method for probe generation
US11519033B2 (en)	2018-08-28	2022-12-06	10X Genomics, Inc.	Method for transposase-mediated spatial tagging and analyzing genomic DNA in a biological sample
CA3113271A1 (en)	2018-10-26	2020-04-30	Illumina, Inc.	Modulating polymer beads for dna processing
EP3873469A2 (de)	2018-11-01	2021-09-08	Kura Oncology, Inc.	Verfahren zur behandlung von krebs mit farnesyltransferase-inhibitoren
WO2020101795A1 (en)	2018-11-15	2020-05-22	Omniome, Inc.	Electronic detection of nucleic acid structure
MX2021003771A (es)	2018-11-30	2021-05-27	Illumina Inc	Analisis de analitos multiples usando un ensayo unico.
CN211311438U (zh)	2018-12-04	2020-08-21	欧姆尼欧美公司	流动池
WO2020118255A1 (en)	2018-12-07	2020-06-11	Element Biosciences, Inc.	Flow cell device and use thereof
US20220290217A1 (en)	2018-12-10	2022-09-15	10X Genomics, Inc.	Resolving spatial arrays using deconvolution
US20220025449A1 (en)	2018-12-14	2022-01-27	Seegene, Inc.	Method for detecting a target analyte in a sample using an s-shaped function for a slope data set
CA3124170A1 (en)	2018-12-18	2020-06-25	Abbott Molecular Inc.	Assay for detecting human papilloma virus (hpv)
BR112020026667A2 (pt)	2018-12-19	2021-07-27	Illumina, Inc.	métodos para melhorar a prioridade de clonalidade do agrupamento de polinucleotídeo
WO2020132350A2 (en)	2018-12-20	2020-06-25	Omniome, Inc.	Temperature control for analysis of nucleic acids and other analytes
WO2020139871A1 (en)	2018-12-26	2020-07-02	Twist Bioscience Corporation	Highly accurate de novo polynucleotide synthesis
US11926867B2 (en)	2019-01-06	2024-03-12	10X Genomics, Inc.	Generating capture probes for spatial analysis
US11649485B2 (en)	2019-01-06	2023-05-16	10X Genomics, Inc.	Generating capture probes for spatial analysis
US12233390B2 (en)	2019-01-31	2025-02-25	Miroculus Inc.	Nonfouling compositions and methods for manipulating and processing encapsulated droplets
CN113613787B (zh)	2019-02-20	2023-06-13	加利福尼亚太平洋生物科学股份有限公司	用于检测化学和生物分析物的扫描装置和方法
WO2020176678A1 (en)	2019-02-26	2020-09-03	Twist Bioscience Corporation	Variant nucleic acid libraries for glp1 receptor
AU2020227802A1 (en)	2019-02-26	2021-10-14	Twist Bioscience Corporation	Variant nucleic acid libraries for antibody optimization
WO2020176816A1 (en)	2019-02-28	2020-09-03	Miroculus Inc.	Digital microfluidics devices and methods of using them
US12624350B2 (en)	2019-03-01	2026-05-12	Illumina, Inc.	High-throughput single-nuclei and single-cell libraries and methods of making and of using
WO2020180663A1 (en)	2019-03-01	2020-09-10	Kura Oncology, Inc.	Methods of treating cancer with farnesyltransferase inhibitors
JP7687957B2 (ja)	2019-03-14	2025-06-03	インシリクサ，インコーポレイテッド	時間ゲート蛍光ベースの検出のための方法およびシステム
JP7413362B2 (ja)	2019-03-29	2024-01-15	シスメックス株式会社	新規人工核酸、その製造方法及び用途
SG11202110472WA (en)	2019-03-29	2021-10-28	Kura Oncology Inc	Methods of treating squamous cell carcinomas with farnesyltransferase inhibitors
US20220168296A1 (en)	2019-04-01	2022-06-02	Kura Oncology, Inc.	Methods of treating cancer with farnesyltransferase inhibitors
US11738345B2 (en)	2019-04-08	2023-08-29	Miroculus Inc.	Multi-cartridge digital microfluidics apparatuses and methods of use
US20220305001A1 (en)	2019-05-02	2022-09-29	Kura Oncology, Inc.	Methods of treating acute myeloid leukemia with farnesyltransferase inhibitors
EP3976820A1 (de)	2019-05-30	2022-04-06	10X Genomics, Inc.	Verfahren zum nachweis der räumlichen heterogenität einer biologischen probe
WO2020252186A1 (en)	2019-06-11	2020-12-17	Omniome, Inc.	Calibrated focus sensing
CA3144644A1 (en)	2019-06-21	2020-12-24	Twist Bioscience Corporation	Barcode-based nucleic acid sequence assembly
AU2020312787A1 (en)	2019-07-12	2021-06-17	Illumina Cambridge Limited	Nucleic acid library preparation using electrophoresis
SG11202105836XA (en)	2019-07-12	2021-07-29	Illumina Cambridge Ltd	Compositions and methods for preparing nucleic acid sequencing libraries using crispr/cas9 immobilized on a solid support
US10656368B1 (en)	2019-07-24	2020-05-19	Omniome, Inc.	Method and system for biological imaging using a wide field objective lens
US11524298B2 (en)	2019-07-25	2022-12-13	Miroculus Inc.	Digital microfluidics devices and methods of use thereof
AU2020335996A1 (en)	2019-08-23	2022-03-31	Gen-Probe Incorporated	Compositions, methods and kits for detecting Treponema pallidum
TW202124406A (zh)	2019-09-10	2021-07-01	美商歐姆尼歐美公司	核苷酸之可逆修飾
EP4034564A4 (de)	2019-09-23	2023-12-13	Twist Bioscience Corporation	Variante nukleinsäurebibliotheken für einzeldomänenantikörper
US12091777B2 (en)	2019-09-23	2024-09-17	Twist Bioscience Corporation	Variant nucleic acid libraries for CRTH2
WO2021080629A1 (en)	2019-10-23	2021-04-29	Elitechgroup, Inc.	Methods for true isothermal strand displacement amplification
EP4055185A1 (de)	2019-11-08	2022-09-14	10X Genomics, Inc.	Räumlich markierte analytfänger für analyt-multiplexing
WO2021092433A2 (en)	2019-11-08	2021-05-14	10X Genomics, Inc.	Enhancing specificity of analyte binding
EP4361284B1 (de)	2019-12-09	2025-09-10	Gen-Probe Incorporated	Quantifizierung von polynukleotidanalyten aus getrockneten proben
BR112022011235A2 (pt)	2019-12-09	2022-12-13	Twist Bioscience Corp	Bibliotecas de variantes de ácido nucleico para receptores de adenosina
MX2021011847A (es)	2019-12-19	2021-11-17	Illumina Inc	Genotecas de celulas unicas de alto rendimiento y metodos para elaborarlas y usarlas.
CN121022991A (zh)	2019-12-23	2025-11-28	10X基因组学有限公司	使用rna模板化连接进行空间分析的方法
EP4081777B1 (de)	2019-12-23	2026-02-18	10X Genomics, Inc.	Reversible fixierreagenzien und verfahren zu deren verwendung
EP4081656A1 (de)	2019-12-23	2022-11-02	10X Genomics, Inc.	Zusammensetzungen und verfahren zur verwendung von fixierten biologischen proben bei partitionsbasierten tests
US12365942B2 (en)	2020-01-13	2025-07-22	10X Genomics, Inc.	Methods of decreasing background on a spatial array
US12405264B2 (en)	2020-01-17	2025-09-02	10X Genomics, Inc.	Electrophoretic system and method for analyte capture
US11732299B2 (en)	2020-01-21	2023-08-22	10X Genomics, Inc.	Spatial assays with perturbed cells
US11702693B2 (en)	2020-01-21	2023-07-18	10X Genomics, Inc.	Methods for printing cells and generating arrays of barcoded cells
US20210230681A1 (en)	2020-01-24	2021-07-29	10X Genomics, Inc.	Methods for spatial analysis using proximity ligation
CA3167895A1 (en)	2020-01-25	2021-07-29	Sense Biodetection Limited	Virus detection
US11821035B1 (en)	2020-01-29	2023-11-21	10X Genomics, Inc.	Compositions and methods of making gene expression libraries
US12076701B2 (en)	2020-01-31	2024-09-03	10X Genomics, Inc.	Capturing oligonucleotides in spatial transcriptomics
US11898205B2 (en)	2020-02-03	2024-02-13	10X Genomics, Inc.	Increasing capture efficiency of spatial assays
US12110541B2 (en)	2020-02-03	2024-10-08	10X Genomics, Inc.	Methods for preparing high-resolution spatial arrays
WO2021158511A1 (en)	2020-02-04	2021-08-12	Omniome, Inc.	Flow cells and methods for their manufacture and use
US11732300B2 (en)	2020-02-05	2023-08-22	10X Genomics, Inc.	Increasing efficiency of spatial analysis in a biological sample
WO2021158925A1 (en)	2020-02-07	2021-08-12	10X Genomics, Inc.	Quantitative and automated permeabilization performance evaluation for spatial transcriptomics
US11835462B2 (en)	2020-02-11	2023-12-05	10X Genomics, Inc.	Methods and compositions for partitioning a biological sample
US12399123B1 (en)	2020-02-14	2025-08-26	10X Genomics, Inc.	Spatial targeting of analytes
US12281357B1 (en)	2020-02-14	2025-04-22	10X Genomics, Inc.	In situ spatial barcoding
US11891654B2 (en)	2020-02-24	2024-02-06	10X Genomics, Inc.	Methods of making gene expression libraries
US11926863B1 (en)	2020-02-27	2024-03-12	10X Genomics, Inc.	Solid state single cell method for analyzing fixed biological cells
US11768175B1 (en)	2020-03-04	2023-09-26	10X Genomics, Inc.	Electrophoretic methods for spatial analysis
EP4127220B1 (de)	2020-03-30	2024-06-05	Illumina, Inc.	Verfahren und zusammensetzungen zur herstellung von nukleinsäurebibliotheken
WO2021216708A1 (en)	2020-04-22	2021-10-28	10X Genomics, Inc.	Methods for spatial analysis using targeted rna depletion
BR112022021086A2 (pt)	2020-04-30	2022-12-13	Stab Vida Investig E Servicos Em Ciencias Biologicas Lda	Sistema integrado para a detecção e identificação de sequências específicas de ácidos nucleicos e método de utilização do sistema integrado
EP4150065A2 (de)	2020-05-12	2023-03-22	Illumina Inc	Erzeugung von nukleinsäuren mit modifizierten basen unter verwendung rekombinanter terminaler deoxynucleotidyltransferase
CN116134308B (zh)	2020-05-19	2025-05-27	10X基因组学有限公司	电泳盒和仪器
EP4414459B1 (de)	2020-05-22	2025-09-03	10X Genomics, Inc.	Simultane räumlich-zeitliche messung der genexpression und der zellaktivität
WO2021237087A1 (en)	2020-05-22	2021-11-25	10X Genomics, Inc.	Spatial analysis to detect sequence variants
WO2021242834A1 (en)	2020-05-26	2021-12-02	10X Genomics, Inc.	Method for resetting an array
WO2021247543A2 (en)	2020-06-02	2021-12-09	10X Genomics, Inc.	Nucleic acid library methods
EP4158054B1 (de)	2020-06-02	2025-04-16	10X Genomics, Inc.	Räumliche transkriptomik für antigenrezeptoren
US12265079B1 (en)	2020-06-02	2025-04-01	10X Genomics, Inc.	Systems and methods for detecting analytes from captured single biological particles
US12031177B1 (en)	2020-06-04	2024-07-09	10X Genomics, Inc.	Methods of enhancing spatial resolution of transcripts
WO2021252499A1 (en)	2020-06-08	2021-12-16	10X Genomics, Inc.	Methods of determining a surgical margin and methods of use thereof
US20230193356A1 (en)	2020-06-08	2023-06-22	The Broad Institute, Inc.	Single cell combinatorial indexing from amplified nucleic acids
WO2021252617A1 (en)	2020-06-09	2021-12-16	Illumina, Inc.	Methods for increasing yield of sequencing libraries
WO2021252747A1 (en)	2020-06-10	2021-12-16	1Ox Genomics, Inc.	Fluid delivery methods
US12435363B1 (en)	2020-06-10	2025-10-07	10X Genomics, Inc.	Materials and methods for spatial transcriptomics
EP4446430A3 (de)	2020-06-10	2024-12-18	10X Genomics, Inc.	Verfahren zur bestimmung einer position eines analyten in einer biologischen probe
WO2021252574A1 (en)	2020-06-10	2021-12-16	Sera Prognostics, Inc.	Nucleic acid biomarkers for placental dysfunction
WO2021263111A1 (en)	2020-06-25	2021-12-30	10X Genomics, Inc.	Spatial analysis of dna methylation
EP4172364A1 (de)	2020-06-30	2023-05-03	Illumina, Inc.	Katalytisch gesteuerte sequenzierung durch synthese zur herstellung von narbenfreier dna
US12209280B1 (en)	2020-07-06	2025-01-28	10X Genomics, Inc.	Methods of identifying abundance and location of an analyte in a biological sample using second strand synthesis
US11761038B1 (en)	2020-07-06	2023-09-19	10X Genomics, Inc.	Methods for identifying a location of an RNA in a biological sample
US11981960B1 (en)	2020-07-06	2024-05-14	10X Genomics, Inc.	Spatial analysis utilizing degradable hydrogels
US20230271189A1 (en)	2020-07-31	2023-08-31	Seegene, Inc.	Thermal cycler comprising damping module
CA3190588A1 (en)	2020-08-06	2022-02-10	Illumina, Inc.	Preparation of rna and dna sequencing libraries using bead-linked transposomes
US12553898B1 (en)	2020-08-10	2026-02-17	10X Genomics, Inc.	Fluorescent hybridization of antibody-oligonucleotide for multiplexing and signal amplification
IL299783A (en)	2020-08-18	2023-03-01	Illumina Inc	Sequence-Specific Targeted Transposition, Selection and Sorting of Nucleic Acids
US11981958B1 (en)	2020-08-20	2024-05-14	10X Genomics, Inc.	Methods for spatial analysis using DNA capture
IL300983A (en)	2020-09-11	2023-04-01	Illumina Cambridge Ltd	Methods for enriching a target sequence from a sequence library using hairpin adapters
WO2022061150A2 (en)	2020-09-18	2022-03-24	10X Geonomics, Inc.	Sample handling apparatus and image registration methods
US11926822B1 (en)	2020-09-23	2024-03-12	10X Genomics, Inc.	Three-dimensional spatial analysis
CN116322706B (zh)	2020-09-25	2025-12-05	株式会社理真思	新人工核酸、其制造方法和用途
CN116964226A (zh)	2020-11-05	2023-10-27	贝克顿迪金森公司	副溶血弧菌的快速鉴定和分型
CA3193878A1 (en)	2020-11-05	2022-05-12	Qiufeng ZHANG	Multiplex detection and typing of vibrio cholerae
US20230407412A1 (en)	2020-11-05	2023-12-21	Becton, Dickinson And Company	Multiplex detection of bacterial respiratory pathogens
US11827935B1 (en)	2020-11-19	2023-11-28	10X Genomics, Inc.	Methods for spatial analysis using rolling circle amplification and detection probes
EP4121555B1 (de)	2020-12-21	2026-02-25	10X Genomics, Inc.	Verfahren zur erfassung von sonden und/oder barcodes
ES3015114T3 (en)	2021-02-04	2025-04-29	Illumina Inc	Long indexed-linked read generation on transposome bound beads
EP4421491A3 (de)	2021-02-19	2024-11-27	10X Genomics, Inc.	Verfahren zur verwendung einer modularen testträgervorrichtung
AU2022238446A1 (en)	2021-03-18	2023-09-07	10X Genomics, Inc.	Multiplex capture of gene and protein expression from a biological sample
CA3210451A1 (en)	2021-03-22	2022-09-29	Illumina Cambridge Limited	Methods for improving nucleic acid cluster clonality
CA3214282A1 (en)	2021-03-29	2022-10-06	Illumina, Inc.	Compositions and methods for assessing dna damage in a library and normalizing amplicon size bias
JP2024511766A (ja)	2021-03-29	2024-03-15	イルミナインコーポレイテッド	改善されたライブラリ調製方法
MX2023010495A (es)	2021-03-30	2023-09-18	Illumina Inc	Metodos mejorados de preparacion de genoteca y adn complementarios isotermicos.
KR20230164668A (ko)	2021-03-31	2023-12-04	일루미나, 인코포레이티드	오류 수정을 위한 고유 분자 식별자를 이용한 트랜스포존-기반 기술을 사용하는 방향성 태그먼트화 시퀀싱 라이브러리 제조 방법
EP4428246B1 (de)	2021-04-14	2025-12-24	10X Genomics, Inc.	Verfahren zur messung der fehllokalisierung eines analyten
EP4320271B1 (de)	2021-05-06	2025-03-19	10X Genomics, Inc.	Verfahren zur erhöhung der auflösung von räumlicher analyse
WO2022256503A1 (en)	2021-06-03	2022-12-08	10X Genomics, Inc.	Methods, compositions, kits, and systems for enhancing analyte capture for spatial analysis
WO2022265965A1 (en)	2021-06-14	2022-12-22	10X Genomics, Inc.	Reverse transcriptase variants for improved performance
US12570831B2 (en)	2021-06-15	2026-03-10	Illumina, Inc.	Hydrogel-free surface functionalization for sequencing
EP4361643A4 (de)	2021-06-24	2025-07-16	Seegene Inc	Automatisiertes analysesystem mit individuell betriebenen biologischen vorrichtungen, analyseverfahren und speichermedium
CN118234564A (zh)	2021-07-09	2024-06-21	塞弗德公司	高级多路复用反应容器、试剂点样装置和相关方法
IL310256A (en)	2021-07-21	2024-03-01	Seegene Inc	Complex analysis system, method and computer-readable recording means
GB2629259B (en)	2021-07-21	2025-05-28	Element Biosciences Inc	Optical systems for nucleic acid sequencing and methods thereof
WO2023004357A1 (en)	2021-07-23	2023-01-26	Illumina, Inc.	Methods for preparing substrate surface for dna sequencing
US12553805B2 (en)	2021-08-02	2026-02-17	10X Genomics, Inc.	Methods of preserving a biological sample
WO2023014222A1 (en)	2021-08-03	2023-02-09	Wageningen Universiteit	Argonaute-based nucleic acid detection system
WO2023021330A1 (en)	2021-08-16	2023-02-23	University Of Oslo	Compositions and methods for determining a treatment course of action
CN118103750A (zh)	2021-08-31	2024-05-28	伊鲁米纳公司	具有增强的孔成像分辨率的流动池
EP4196605B1 (de)	2021-09-01	2024-12-04	10X Genomics, Inc.	Verfahren zur blockierung einer erfassungssonde auf einer räumlichen anordnung
WO2023054848A1 (ko)	2021-09-30	2023-04-06	주식회사 씨젠	분자진단 시스템의 샘플 처리 및 분석 방법
CA3234961A1 (en)	2021-10-20	2023-04-27	Illumina, Inc.	Methods for capturing library dna for sequencing
WO2023086880A1 (en)	2021-11-10	2023-05-19	10X Genomics, Inc.	Methods, compositions, and kits for determining the location of an analyte in a biological sample
WO2023102118A2 (en)	2021-12-01	2023-06-08	10X Genomics, Inc.	Methods, compositions, and systems for improved in situ detection of analytes and spatial analysis
EP4441711A1 (de)	2021-12-20	2024-10-09	10X Genomics, Inc.	Selbsttest für eine pathologie-/histologie-objektträgerbildgebungsvorrichtung
EP4458836A4 (de)	2021-12-27	2025-05-21	Riken Genesis Co., Ltd.	Neuartige künstliche nukleinsäure, verfahren zur herstellung davon und verwendung davon
US11772093B2 (en)	2022-01-12	2023-10-03	Miroculus Inc.	Methods of mechanical microfluidic manipulation
AU2023208743A1 (en)	2022-01-20	2024-01-04	Illumina, Inc.	Methods of detecting methylcytosine and hydroxymethylcytosine by sequencing
WO2023152568A2 (en)	2022-02-10	2023-08-17	Oslo Universitetssykehus Hf	Compositions and methods for characterizing lung cancer
EP4493716A1 (de)	2022-03-15	2025-01-22	Diagenode S.A.	Nachweis des methylierungsstatus einer dna-probe
EP4504930A1 (de)	2022-04-07	2025-02-12	Illumina, Inc.	Veränderte cytidindeaminasen und verfahren zur verwendung
WO2024015331A1 (en)	2022-07-12	2024-01-18	Genentech, Inc.	Therapeutic and diagnostic methods for multiple sclerosis
EP4594482A1 (de)	2022-09-30	2025-08-06	Illumina, Inc.	Cytidindeaminasen und verfahren zur verwendung bei der kartierung modifizierter cytosinnukleotide
WO2024073659A1 (en)	2022-09-30	2024-04-04	Biotheranostics, Inc.	Biomarker assay to select breast cancer therapy
CN120153070A (zh)	2022-09-30	2025-06-13	因美纳有限公司	解旋酶-胞苷脱氨酶复合物及其使用方法
US20250388894A1 (en)	2022-09-30	2025-12-25	Illumina, Inc.	Methods of using cpg binding proteins in mapping modified cytosine nucleotides
WO2024090987A1 (ko)	2022-10-25	2024-05-02	주식회사 씨젠	분자 진단용 어플리케이션을 관리하는 방법 및 장치
WO2024102809A1 (en)	2022-11-09	2024-05-16	10X Genomics, Inc.	Methods, compositions, and kits for determining the location of multiple analytes in a biological sample
CN120603940A (zh) *	2022-11-11	2025-09-05	生米公司	用于处理和扩增核酸的方法和组合物
KR20250130601A (ko)	2022-11-29	2025-09-02	엘리먼트 바이오사이언스, 인크.	핵산 시퀀싱을 위한 플로우 셀 디바이스 및 광학 시스템
WO2024129969A1 (en)	2022-12-14	2024-06-20	Illumina, Inc.	Systems and methods for capture and enrichment of clustered beads on flow cell substrates
KR20240149485A (ko)	2023-04-05	2024-10-15	크로마흐 주식회사	감염성 질환 인플루엔자 b의 현장진단을 위한 핵산 증폭 관련 조성물 및 이의 용도
AU2024267362A1 (en)	2023-05-05	2025-11-13	Gen-Probe Incorporated	Method and system for improving specificity of analyte detection using real-time nucleic acid amplification
WO2024238992A1 (en)	2023-05-18	2024-11-21	10X Genomics, Inc.	Engineered non-strand displacing family b polymerases for reverse transcription and gap-fill applications
KR102891704B1 (ko)	2023-07-24	2025-12-01	크로마흐 주식회사	감염성 질환 인플루엔자 b의 현장진단을 위한 핵산 증폭 관련 하이드로겔 조성물 및 이의 용도
KR20250018195A (ko)	2023-07-26	2025-02-05	임진동	바이러스의 확산 방지를 위한 현장진단용 검출 방법 및 조성물
KR20250018194A (ko)	2023-07-26	2025-02-05	최호윤	비말을 통해 감염되는 질환의 현장확진을 위한 핵산 증폭 증폭용 조성물 및 검출을 위한 방법
WO2025072783A1 (en)	2023-09-28	2025-04-03	Illumina, Inc.	Altered cytidine deaminases and methods of use
WO2025081064A2 (en)	2023-10-11	2025-04-17	Illumina, Inc.	Thermophilic deaminase and methods for identifying modified cytosine
WO2025137222A1 (en)	2023-12-19	2025-06-26	Illumina, Inc.	Methylation detection assay
WO2025240905A1 (en)	2024-05-17	2025-11-20	The Broad Institute, Inc.	Imaging-free high-resolution spatial macromolecule abundance reconstruction
WO2025264836A1 (en)	2024-06-18	2025-12-26	Illumina, Inc.	Methods for increasing sequencing quality of gc-rich regions
WO2025264831A1 (en)	2024-06-18	2025-12-26	Illumina, Inc.	Methods for increasing sequencing quality of gc-rich regions
WO2026006314A1 (en)	2024-06-28	2026-01-02	Illumina, Inc.	Tagging target regions prior to nucleotide sequencing
WO2026006774A1 (en)	2024-06-28	2026-01-02	Illumina, Inc.	Altered cytidine deaminases and methods of use
WO2026090042A1 (en)	2024-10-21	2026-04-30	The Broad Institute, Inc.	Single-cell and spatial dna methylation measurements

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4766064A (en) *	1984-05-07	1988-08-23	Allied Corporation	Displacement polynucleotide assay employing polyether and diagnostic kit
US4683195A (en) *	1986-01-30	1987-07-28	Cetus Corporation	Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) *	1985-03-28	1987-07-28	Cetus Corporation	Process for amplifying nucleic acid sequences
GB8515276D0 (en) *	1985-06-17	1985-07-17	Amersham Int Plc	Nucleic acid sequencing
AU6403886A (en) *	1985-09-18	1987-04-07	Yale University	Reca nucleoprotein filament and methods
JPH04501353A (ja) *	1988-07-26	1992-03-12	ジエネラブス・テクノロジーズ・インコーポレイテツド	Ｒｎａ及びｄｎａ増幅法
DE3930312A1 (de) *	1988-10-24	1990-04-26	Max Planck Gesellschaft	Verfahren zur direkten sequenzierung von nukleinsaeureketten
EP0390323B2 (de) *	1989-03-29	2012-08-08	Johns Hopkins University	Nachweis des Ausfalls des Wildtyps des p53-Gens
US5043272A (en) *	1989-04-27	1991-08-27	Life Technologies, Incorporated	Amplification of nucleic acid sequences using oligonucleotides of random sequence as primers
CA2037349C (en) *	1990-03-26	2008-06-17	James G. Wetmur	Branch migration of nucleotides
US5270184A (en) *	1991-11-19	1993-12-14	Becton, Dickinson And Company	Nucleic acid target generation

1992
- 1992-01-09 US US07/819,358 patent/US5455166A/en not_active Expired - Lifetime
- 1992-01-28 EP EP92101348A patent/EP0497272B1/de not_active Expired - Lifetime
- 1992-01-28 AT AT92101348T patent/ATE128737T1/de not_active IP Right Cessation
- 1992-01-28 DE DE69205181T patent/DE69205181T2/de not_active Expired - Lifetime
- 1992-01-28 DK DK92101348.8T patent/DK0497272T3/da active
- 1992-01-28 ES ES92101348T patent/ES2077887T3/es not_active Expired - Lifetime
- 1992-01-30 KR KR1019920001346A patent/KR950003619B1/ko not_active Expired - Fee Related
- 1992-01-30 CA CA002060372A patent/CA2060372C/en not_active Expired - Lifetime
- 1992-01-31 JP JP4016682A patent/JPH07114718B2/ja not_active Expired - Lifetime
- 1992-01-31 AU AU10699/92A patent/AU659429B2/en not_active Expired
1995
- 1995-01-18 US US08/375,133 patent/US5712124A/en not_active Expired - Lifetime
- 1995-11-30 GR GR950403389T patent/GR3018271T3/el unknown

Also Published As

Publication number	Publication date
US5455166A (en)	1995-10-03
KR950003619B1 (ko)	1995-04-17
AU659429B2 (en)	1995-05-18
AU1069992A (en)	1993-07-29
CA2060372C (en)	1999-06-01
JPH07114718B2 (ja)	1995-12-13
DE69205181D1 (de)	1995-11-09
US5712124A (en)	1998-01-27
EP0497272B1 (de)	1995-10-04
DK0497272T3 (da)	1996-01-29
ES2077887T3 (es)	1995-12-01
KR920014937A (ko)	1992-08-25
CA2060372A1 (en)	1992-08-01
GR3018271T3 (en)	1996-02-29
EP0497272A1 (de)	1992-08-05
JPH05192195A (ja)	1993-08-03
DE69205181T2 (de)	1996-03-21

Legal Events

Date	Code	Title	Description
1996-04-15	UEP	Publication of translation of european patent specification
2012-04-15	EELA	Cancelled due to lapse of time

Publication	Publication Date	Title
DE69205181D1 (de)	1995-11-09	Strangverdrängungsamplifikation.
ES2114692T3 (es)	1998-06-01	Reaccion en ciclos magneticos.
ATE207543T1 (de)	2001-11-15	Isotherme amplifikation von nukleinsäuren durch strangverdrängung
ATE247174T1 (de)	2003-08-15	Verfahren zum besonders sensitiven nachweis von nukleinsäuren
DE69636080D1 (de)	2006-06-01	Eine in Kaskaden verlaufende Vervielfältigungsreaktion von Nukleinsäuren
ATE159763T1 (de)	1997-11-15	Nuklein-säure amplifikation mit dns abhängigen rns polymerasen aktivität von rns-replikasen
ATE214095T1 (de)	2002-03-15	Verwendung einer exo-nukleotidprobe in der genklonierung
NO950381D0 (no)	1995-02-02	Nukleinsyresekvens amplifikasjon
DE69213112D1 (de)	1996-10-02	Verbesserte Methoden zur Nukleinsäure-Amplifizierung
CA2082842A1 (en)	1993-05-20	Nucleic acid target generation
DK0417842T3 (da)	1996-05-06	Diagnose- og amplifikationsfremgangsmåder, der overvinder fejlparring mellem primer og målsekvens på primerens 3-ende
NO854710L (no)	1987-05-26	Fremgangsmåte for kontroll og styring av injeksjonssonens utstrekning ved jetinjisering av herdbart bindemiddel i jordarter, samt anordning for gjennomføring av fremgangsmåten.
DE69732505D1 (de)	2005-03-24	Kit enthaltend Reagenzien zur Amplifizierung und Erkennung von Nukleinsäuren von Cytomegalovirus (CMV) mit der Nukleinsäuresequenz ss2.7
ATE142702T1 (de)	1996-09-15	Spezifischer nachweis von mycobacterium tuberculosis
FI923239A0 (fi)	1992-07-15	Immobilisering av nukleinsyror.
DE3676276D1 (de)	1991-01-31	Korrosionsgehemmter kondensationsofen, vorrichtung und verfahren.
FI910238A0 (fi)	1991-01-16	Foerfarande foer framstaellning av modifierade nukleinsyror.
NO940658D0 (no)	1994-02-25	Nukleinsyre-polymerase-forökning
WO1998030717A3 (en)	1999-04-29	Vegetal sequences including a polymorphic site and their uses
MY110525A (en)	1998-07-31	Strand displacement amplification
DE69230345D1 (de)	1999-12-30	Nachweis von einem genort
DE3679823D1 (de)	1991-07-18	Verfahren zur herstellung von bitumen mit hohen penetrationswerten, vorrichtung zu ihrer durchfuehrung und damit gewonnene produkte.
NO301890B1 (no)	1997-12-22	Fremgangsmåte for forsterkning av minst en spesifikk nukleinsyre-sekvens samt anvendelse av fremgangsmåten
DE3771490D1 (de)	1991-08-22	Filiformkorrosionsresistente primerzusammensetzung und methode zur verhuetung von filiformkorrosion.