CN1290848C - 作为治疗或预防糖尿病的二肽基肽酶抑制剂的β－氨基四氢咪唑并(1,2－A)吡嗪和四氢三唑并(4,3－A)吡嗪 - Google Patents

作为治疗或预防糖尿病的二肽基肽酶抑制剂的β－氨基四氢咪唑并(1,2－A)吡嗪和四氢三唑并(4,3－A)吡嗪 Download PDF

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Publication number
CN1290848C
CN1290848C CNB02813558XA CN02813558A CN1290848C CN 1290848 C CN1290848 C CN 1290848C CN B02813558X A CNB02813558X A CN B02813558XA CN 02813558 A CN02813558 A CN 02813558A CN 1290848 C CN1290848 C CN 1290848C
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compound
phenyl
alkyl
substituted
compounds
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CN1524082A (zh
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S·D·埃蒙森
M·H·费舍尔
D·金
M·麦科斯
E·R·帕梅
A·E·韦伯
徐锦优
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Merck Sharp and Dohme LLC
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Merck and Co Inc
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
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    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
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CNB02813558XA 2001-07-06 2002-07-05 作为治疗或预防糖尿病的二肽基肽酶抑制剂的β－氨基四氢咪唑并(1,2－A)吡嗪和四氢三唑并(4,3－A)吡嗪 Expired - Lifetime CN1290848C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30347401P 2001-07-06 2001-07-06
US60/303,474 2001-07-06

Related Child Applications (1)

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CNA2006100776910A Division CN1861077A (zh) 2001-07-06 2002-07-05 作为治疗或预防糖尿病的二肽基肽酶抑制剂的β－氨基四氢咪唑并(1,2－A)吡嗪和四氢三唑并(4,3－A)吡嗪

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CN1524082A CN1524082A (zh) 2004-08-25
CN1290848C true CN1290848C (zh) 2006-12-20

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CNB02813558XA Expired - Lifetime CN1290848C (zh) 2001-07-06 2002-07-05 作为治疗或预防糖尿病的二肽基肽酶抑制剂的β－氨基四氢咪唑并(1,2－A)吡嗪和四氢三唑并(4,3－A)吡嗪
CNA2006100776910A Pending CN1861077A (zh) 2001-07-06 2002-07-05 作为治疗或预防糖尿病的二肽基肽酶抑制剂的β－氨基四氢咪唑并(1,2－A)吡嗪和四氢三唑并(4,3－A)吡嗪

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CNA2006100776910A Pending CN1861077A (zh) 2001-07-06 2002-07-05 作为治疗或预防糖尿病的二肽基肽酶抑制剂的β－氨基四氢咪唑并(1,2－A)吡嗪和四氢三唑并(4,3－A)吡嗪

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US (9) US6699871B2 (2)
EP (4) EP2226324A1 (2)
JP (1) JP3762407B2 (2)
KR (1) KR100606871B1 (2)
CN (2) CN1290848C (2)
AR (1) AR036114A1 (2)
AT (2) ATE471148T1 (2)
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CN102030683A (zh) * 2009-09-27 2011-04-27 浙江九洲药业股份有限公司 西他列汀中间体及其制备方法和用途

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