DK1762576T3 - Fremgangsmåde til adskillelse af alfa-1-proteinaseinhibitoren fra Cohn-fraktion IV1 plus IV4-pasta - Google Patents

Fremgangsmåde til adskillelse af alfa-1-proteinaseinhibitoren fra Cohn-fraktion IV1 plus IV4-pasta

Info

Publication number
DK1762576T3
DK1762576T3 DK06025342T DK06025342T DK1762576T3 DK 1762576 T3 DK1762576 T3 DK 1762576T3 DK 06025342 T DK06025342 T DK 06025342T DK 06025342 T DK06025342 T DK 06025342T DK 1762576 T3 DK1762576 T3 DK 1762576T3
Authority
DK
Denmark
Prior art keywords
alpha
paste
plus
separation
proteinase inhibitor
Prior art date
Application number
DK06025342T
Other languages
Danish (da)
English (en)
Inventor
Duk Sung Hwang
Evelyn Nario
Mark Lepe
Lyndon Luz
Hirokazu Ito
Kazuo Takechi
Original Assignee
Baxter Int
Baxter Healthcare Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24701177&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1762576(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Baxter Int, Baxter Healthcare Sa filed Critical Baxter Int
Application granted granted Critical
Publication of DK1762576T3 publication Critical patent/DK1762576T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/775—Apolipopeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins
    • C07K14/8125—Alpha-1-antitrypsin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/811—Peptides or proteins is immobilized on, or in, an inorganic carrier
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Meat, Egg Or Seafood Products (AREA)
DK06025342T 1996-07-01 1997-06-27 Fremgangsmåde til adskillelse af alfa-1-proteinaseinhibitoren fra Cohn-fraktion IV1 plus IV4-pasta DK1762576T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/673,064 US5616693A (en) 1996-07-01 1996-07-01 Process for seperating alpha-1-proteinase inhibitor from COHN IV1 +1V4 paste
PCT/US1997/011256 WO1998000154A1 (en) 1996-07-01 1997-06-27 Process for separating alpha-1-proteinase inhibitor from cohn fraction iv1 +iv4 paste

Publications (1)

Publication Number Publication Date
DK1762576T3 true DK1762576T3 (da) 2009-04-20

Family

ID=24701177

Family Applications (2)

Application Number Title Priority Date Filing Date
DK06025342T DK1762576T3 (da) 1996-07-01 1997-06-27 Fremgangsmåde til adskillelse af alfa-1-proteinaseinhibitoren fra Cohn-fraktion IV1 plus IV4-pasta
DK97932347T DK0944392T3 (da) 1996-07-01 1997-06-27 Fremgangsmåde til fraskillelse af alpha-1-proteinase-inhibitor fra Cohn-fraktion IV1 + IV4-pasta

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK97932347T DK0944392T3 (da) 1996-07-01 1997-06-27 Fremgangsmåde til fraskillelse af alpha-1-proteinase-inhibitor fra Cohn-fraktion IV1 + IV4-pasta

Country Status (16)

Country Link
US (2) US5616693A (de)
EP (2) EP0944392B1 (de)
JP (3) JP4390855B2 (de)
KR (1) KR20000022480A (de)
AT (2) ATE420111T1 (de)
AU (1) AU726233B2 (de)
BR (1) BR9710107B1 (de)
CA (2) CA2489773A1 (de)
CZ (3) CZ300452B6 (de)
DE (2) DE69739212D1 (de)
DK (2) DK1762576T3 (de)
ES (2) ES2281104T3 (de)
IL (1) IL127774A (de)
PL (3) PL188874B1 (de)
PT (2) PT1762576E (de)
WO (1) WO1998000154A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5616693A (en) * 1996-07-01 1997-04-01 Alpha Therapeutic Corporation Process for seperating alpha-1-proteinase inhibitor from COHN IV1 +1V4 paste
AU3731400A (en) 1999-03-05 2000-09-21 Trustees Of University Technology Corporation, The Methods and compositions useful in inhibiting apoptosis
US6849605B1 (en) * 1999-03-05 2005-02-01 The Trustees Of University Technology Corporation Inhibitors of serine protease activity, methods and compositions for treatment of viral infections
US6489308B1 (en) 1999-03-05 2002-12-03 Trustees Of University Of Technology Corporation Inhibitors of serine protease activity, methods and compositions for treatment of nitric-oxide-induced clinical conditions
AU3864000A (en) * 1999-03-05 2000-09-21 Trustees Of University Technology Corporation, The Inhibitors of serine protease activity, methods and compositions for treatment of herpes viruses
US6462180B1 (en) 1999-11-24 2002-10-08 Bayer Corporation Method of preparing α-1 proteinase inhibitor
NZ526940A (en) 2000-12-14 2005-06-24 Bayer Healthcare Llc Method of preparing alpha-1 proteinase inhibitor
KR100406870B1 (ko) * 2001-05-25 2003-11-21 주식회사 두산 침전법을 이용한 계란 난황에서의 유용 수용성 성분의분리방법 및 침전 부산물의 이용 방법
DE60215823T2 (de) * 2001-08-07 2007-09-06 Novozymes A/S Kohlhydrate und polyole zum lösen der proteinkristalle
ATE420161T1 (de) * 2002-07-01 2009-01-15 Novozymes As Monopropylenglykol als fermentationszusatz
US7777006B2 (en) 2002-12-31 2010-08-17 Csl Behring L.L.C. Method for purification of alpha-1-antitrypsin
US20040220242A1 (en) * 2003-05-02 2004-11-04 Leland Shapiro Inhibitors of serine protease activity, methods and compositions for treatment of nitric oxide induced clinical conditions
PL2520654T3 (pl) * 2003-08-26 2017-08-31 The Regents Of The University Of Colorado, A Body Corporate Inhibitory aktywności proteazy serynowej i ich zastosowanie w sposobach i kompozycjach do leczenia zakażeń bakteryjnych
US7807435B2 (en) 2005-08-11 2010-10-05 Baxter International Inc. Method for the purification of alpha-1 proteinase inhibitor (a1PI)
GB0524432D0 (en) * 2005-11-30 2006-01-11 Nhs Blood & Transplant Method
US20080124303A1 (en) * 2005-12-12 2008-05-29 Cavit Sciences, Inc Methods and compositions for treatment of viral infections
WO2007112953A1 (en) * 2006-03-30 2007-10-11 Baxter Internaional Inc. Process for the purification of recombinant alpha 1-antitrypsin involving a step of anion exchange chromatography
WO2007134800A1 (en) * 2006-05-19 2007-11-29 Baxter International Inc. Ethanol dependence of alpha1 antitrypsin c-terminal lys truncation by basic carboxypeptidases
EP2714093A1 (de) 2011-05-27 2014-04-09 Baxter International Inc. Therapeutische proteine mit erhöhter halbwertzeit und verfahren zu ihrer herstellung
KR20200044138A (ko) 2011-06-24 2020-04-28 더 리젠츠 오브 더 유니버시티 오브 콜로라도, 어 바디 코포레이트 알파-1 안티트립신 융합 분자용 조성물, 방법 및 용도
JP2015504675A (ja) 2012-01-10 2015-02-16 ザ リージェンツ オブ ザ ユニバーシティ オブ コロラド，ア ボディー コーポレイトＴＨＥ ＲＥＧＥＮＴＳ ＯＦ ＴＨＥ ＵＮＩＶＥＲＳＩＴＹ ＯＦ ＣＯＬＯＲＡＤＯ，ａ ｂｏｄｙ ｃｏｒｐｏｒａｔｅ アルファ−１アンチトリプシン融合分子の組成物、方法、及び使用
TWI629283B (zh) 2012-02-23 2018-07-11 巴克斯歐塔公司 來自血漿中的免疫球蛋白之ｉ-ｉｖ-１部分沉澱
US9353165B2 (en) 2012-07-25 2016-05-31 Grifols, S.A. Purification of cell culture derived alpha1 protease inhibitor
ES2799153T3 (es) 2013-03-29 2020-12-15 Univ Colorado Regents Alfa 1 antitripsina para uso en la preparación de un sujeto para trasplante
IL267923B2 (en) 2018-08-02 2023-06-01 Grifols Worldwide Operations Ltd The composition containing the most concentrated alpha-1 type protein inhibitor and a method for obtaining it

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US2770616A (en) * 1951-01-29 1956-11-13 Protein Foundation Inc Fractionation of proteinaceous materials in blood plasma and liver tissue
US2761808A (en) * 1952-09-06 1956-09-04 Ortho Pharma Corp Plasma fractionation process
US4056614A (en) * 1972-09-22 1977-11-01 Marc Bonneau Immunity depressant medicine
JPS52128205A (en) * 1976-04-16 1977-10-27 Green Cross Corp:The Prophylactic and therapeutic drugs for cerebro-vascular contraction
US4379087A (en) * 1982-06-17 1983-04-05 Cutter Laboratories, Inc. Method of preparing alpha-1-proteinase inhibitor
US4439358A (en) * 1982-06-17 1984-03-27 Miles Laboratories, Inc. Method of preparing alpha-1-proteinase inhibitor
US4540573A (en) * 1983-07-14 1985-09-10 New York Blood Center, Inc. Undenatured virus-free biologically active protein derivatives
DE3426903A1 (de) * 1984-07-20 1986-01-23 Biotest Pharma GmbH, 6000 Frankfurt Eine immunglobulinpraeparation in kombination mit einer anderen pharmakologisch wirksamen praeparation zur verwendung bei der behandlung von krankheiten
US4684723A (en) * 1985-09-11 1987-08-04 Miles Laboratories, Inc. Method of separating proteins from aqueous solutions
US4697003A (en) * 1985-11-01 1987-09-29 Miles Laboratories, Inc. Method of preparing alpha-1-proteinase inhibitor
US4656254A (en) * 1985-12-02 1987-04-07 Miles Laboratories, Inc. Method of preparing alpha-1-proteinase inhibitor and antithrombin III
US4629567A (en) * 1986-03-07 1986-12-16 Smithkline-Rit Alpha-1-antiprotease purification
JPS6317899A (ja) * 1986-07-09 1988-01-25 Green Cross Corp:The ハプトグロビンの精製方法
JPS63132898A (ja) * 1986-11-26 1988-06-04 Meito Sangyo Kk 蛋白質の分離精製方法
US5114917A (en) * 1986-12-24 1992-05-19 John Lezdey Treatment of inflammation using alpha 1-antichymotrypsin
US4829054A (en) * 1987-04-13 1989-05-09 Miles Laboratories, Inc. Method of decreasing lung damage in a host following the onset of gram negative septicemia/endotoxemia
DE3877041T2 (de) * 1987-04-27 1993-04-22 Miles Inc Verfahren zur herstellung von hochgereinigtem alpha-1-proteinase-inhibitor.
IL86417A (en) * 1987-05-22 1992-09-06 Armour Pharma Process for the inactivation of pathogens in biological or pharmaceutical material by mixing with aqueous solution containing a sugar(alcohol)and neutral salts as stabilizers
US5073487A (en) * 1989-01-30 1991-12-17 Athens Research And Technology, Inc. Rapid assay for functional human α1 -proteinase inhibitor
FR2672895B1 (fr) * 1991-02-15 1995-05-12 Transgene Sa Procede de purification d'une proteine fortement glycosylee.
US6284874B1 (en) * 1994-06-17 2001-09-04 Alpha Therapeutic Corporation Process for separating α1-proteinase inhibitor from cohn fraction IV1 and IV4 paste
US5610285A (en) * 1994-08-24 1997-03-11 Bayer Corporation Purification of α-1 proteinase inhibitor using novel chromatographic separation conditions
US5616693A (en) * 1996-07-01 1997-04-01 Alpha Therapeutic Corporation Process for seperating alpha-1-proteinase inhibitor from COHN IV1 +1V4 paste

Also Published As

Publication number Publication date
ATE352569T1 (de) 2007-02-15
WO1998000154A1 (en) 1998-01-08
AU3583197A (en) 1998-01-21
PL188830B1 (pl) 2005-04-29
CZ302102B6 (cs) 2010-10-13
JP4588770B2 (ja) 2010-12-01
JP4390855B2 (ja) 2009-12-24
IL127774A0 (en) 1999-10-28
ES2320919T3 (es) 2009-05-29
DK0944392T3 (da) 2007-04-23
BR9710107B1 (pt) 2009-05-05
EP0944392B1 (de) 2007-01-24
ES2281104T3 (es) 2007-09-16
DE69737294T2 (de) 2007-07-12
CA2259499A1 (en) 1998-01-08
JP2009191076A (ja) 2009-08-27
CZ301332B6 (cs) 2010-01-20
CZ435698A3 (cs) 1999-05-12
US5616693A (en) 1997-04-01
AU726233B2 (en) 2000-11-02
DE69737294D1 (de) 2007-03-15
CA2489773A1 (en) 1998-01-08
EP0944392A4 (de) 2004-11-24
PT1762576E (pt) 2009-02-02
CA2259499C (en) 2006-01-24
EP1762576B1 (de) 2009-01-07
JP2000514647A (ja) 2000-11-07
EP0944392A1 (de) 1999-09-29
BR9710107A (pt) 1999-08-10
JP5245079B2 (ja) 2013-07-24
CZ300452B6 (cs) 2009-05-20
KR20000022480A (ko) 2000-04-25
IL127774A (en) 2005-08-31
PL330934A1 (en) 1999-06-07
JP2008120822A (ja) 2008-05-29
PT944392E (pt) 2007-04-30
ATE420111T1 (de) 2009-01-15
PL188874B1 (pl) 2005-05-31
US5981715A (en) 1999-11-09
PL188873B1 (pl) 2005-05-31
DE69739212D1 (de) 2009-02-26
EP1762576A1 (de) 2007-03-14

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