DOP2009000280A - Sales del inhibidor de janus cinasa (r)-3-(4-(7h-pirrolo[2,3-d]pirimidin-4-il)-1h-pirazol-1-il)-3-ciclopentilpropanitrilo - Google Patents

Sales del inhibidor de janus cinasa (r)-3-(4-(7h-pirrolo[2,3-d]pirimidin-4-il)-1h-pirazol-1-il)-3-ciclopentilpropanitrilo

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Publication number
DOP2009000280A
DOP2009000280A DO2009000280A DO2009000280A DOP2009000280A DO P2009000280 A DOP2009000280 A DO P2009000280A DO 2009000280 A DO2009000280 A DO 2009000280A DO 2009000280 A DO2009000280 A DO 2009000280A DO P2009000280 A DOP2009000280 A DO P2009000280A
Authority
DO
Dominican Republic
Prior art keywords
janus
ciclopentilpropanitrilo
cinasa
pirimidin
pirrolo
Prior art date
Application number
DO2009000280A
Other languages
English (en)
Inventor
James D Rodgers
Hui-Yin Li
Original Assignee
Incyte Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40029273&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DOP2009000280(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Incyte Corp filed Critical Incyte Corp
Publication of DOP2009000280A publication Critical patent/DOP2009000280A/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
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    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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Abstract

La presente invencion proporciona formas de sal de (R)-3-(4-(7H-pirrolo[2,3-d]pirimidin-4-il)-1H-pirazol-1-i1)-3 ciclopentilpropanitrilo que son utiles en la modulación de la actividad de la cinasa Janus que incluye, por ejemplo, enfermedades relacionadas con el sistema inmunitario, trastornos de la piel, trastornos proliferativos mieloides, cancer, y otras enfermedades.
DO2009000280A 2007-06-13 2009-12-10 Sales del inhibidor de janus cinasa (r)-3-(4-(7h-pirrolo[2,3-d]pirimidin-4-il)-1h-pirazol-1-il)-3-ciclopentilpropanitrilo DOP2009000280A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US94370507P 2007-06-13 2007-06-13

Publications (1)

Publication Number Publication Date
DOP2009000280A true DOP2009000280A (es) 2010-03-31

Family

ID=40029273

Family Applications (1)

Application Number Title Priority Date Filing Date
DO2009000280A DOP2009000280A (es) 2007-06-13 2009-12-10 Sales del inhibidor de janus cinasa (r)-3-(4-(7h-pirrolo[2,3-d]pirimidin-4-il)-1h-pirazol-1-il)-3-ciclopentilpropanitrilo

Country Status (41)

Country Link
US (10) US20080312259A1 (es)
EP (6) EP2173752B2 (es)
JP (1) JP5475653B2 (es)
KR (2) KR101549876B1 (es)
CN (2) CN101932582B (es)
AU (1) AU2008266183B2 (es)
BR (1) BRPI0814254B8 (es)
CA (1) CA2689663C (es)
CO (1) CO6251256A2 (es)
CR (1) CR11151A (es)
CU (2) CU24179B1 (es)
CY (3) CY1115145T1 (es)
DK (3) DK3070090T3 (es)
DO (1) DOP2009000280A (es)
EA (1) EA019784B1 (es)
EC (1) ECSP099802A (es)
ES (4) ES2467665T5 (es)
GE (1) GEP20125533B (es)
GT (1) GT200900314A (es)
HR (3) HRP20140541T4 (es)
HU (2) HUE029236T2 (es)
IL (5) IL202524A (es)
LT (1) LT3070090T (es)
MA (1) MA31517B1 (es)
ME (1) ME00960B (es)
MX (2) MX342814B (es)
MY (1) MY154969A (es)
NI (1) NI200900216A (es)
NO (1) NO2019025I1 (es)
NZ (1) NZ581803A (es)
PL (3) PL2740731T3 (es)
PT (2) PT2173752E (es)
RS (3) RS58449B1 (es)
SG (3) SG182198A1 (es)
SI (3) SI2740731T1 (es)
SM (1) SMP201000002B (es)
TN (1) TN2009000514A1 (es)
TR (1) TR201903488T4 (es)
UA (1) UA99467C2 (es)
WO (1) WO2008157208A2 (es)
ZA (1) ZA200908826B (es)

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