EG23659A - Process and crystal forms of methyl-thieno-benzodiazepine - Google Patents

Process and crystal forms of methyl-thieno-benzodiazepine

Info

Publication number
EG23659A
EG23659A EG19960250A EG19960250A EG23659A EG 23659 A EG23659 A EG 23659A EG 19960250 A EG19960250 A EG 19960250A EG 19960250 A EG19960250 A EG 19960250A EG 23659 A EG23659 A EG 23659A
Authority
EG
Egypt
Prior art keywords
benzodiazepine
thieno
methyl
crystal forms
crystal
Prior art date
Application number
EG19960250A
Other languages
English (en)
Inventor
Charles Arthur Bunnell
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23621056&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EG23659(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of EG23659A publication Critical patent/EG23659A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicinal Preparation (AREA)
EG19960250A 1995-03-24 1996-03-21 Process and crystal forms of methyl-thieno-benzodiazepine EG23659A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US40956695A 1995-03-24 1995-03-24

Publications (1)

Publication Number Publication Date
EG23659A true EG23659A (en) 2007-03-26

Family

ID=23621056

Family Applications (1)

Application Number Title Priority Date Filing Date
EG19960250A EG23659A (en) 1995-03-24 1996-03-21 Process and crystal forms of methyl-thieno-benzodiazepine

Country Status (48)

Country Link
US (1) US5736541A (fr)
EP (3) EP1445259B1 (fr)
JP (1) JPH11502535A (fr)
KR (1) KR100399688B1 (fr)
CN (1) CN1065536C (fr)
AP (1) AP828A (fr)
AR (2) AR002719A1 (fr)
AT (4) ATE331719T1 (fr)
AU (1) AU706471B2 (fr)
BG (1) BG62619B1 (fr)
BR (1) BR9607790A (fr)
CA (1) CA2214005C (fr)
CH (1) CH690579A5 (fr)
CO (1) CO4650278A1 (fr)
CZ (1) CZ292688B6 (fr)
DE (4) DE69614426T2 (fr)
DK (4) DK1095941T3 (fr)
EA (1) EA000149B1 (fr)
EE (1) EE03489B1 (fr)
EG (1) EG23659A (fr)
ES (3) ES2208220T3 (fr)
FI (1) FI973750A0 (fr)
GB (1) GB2313835B (fr)
HU (1) HU224989B1 (fr)
IL (1) IL117610A (fr)
IS (1) IS1896B (fr)
LT (1) LT4349B (fr)
LU (1) LU90096B1 (fr)
LV (1) LV12018B (fr)
MY (1) MY114701A (fr)
NO (1) NO314663B1 (fr)
NZ (1) NZ306110A (fr)
OA (1) OA10510A (fr)
PA (1) PA8353701A1 (fr)
PE (1) PE44897A1 (fr)
PL (1) PL183723B1 (fr)
PT (3) PT1445259E (fr)
RO (1) RO118872B1 (fr)
SE (1) SE9703205L (fr)
SI (4) SI1095941T1 (fr)
SK (1) SK284143B6 (fr)
SV (1) SV1996000031A (fr)
TR (1) TR199701017T1 (fr)
TW (2) TW513432B (fr)
UA (1) UA44765C2 (fr)
WO (1) WO1996030375A1 (fr)
YU (1) YU49478B (fr)
ZA (2) ZA962342B (fr)

Families Citing this family (84)

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UA48219C2 (uk) * 1996-03-25 2002-08-15 Елі Ліллі Енд Компані Композиція для вгамування болю (варіанти) та спосіб вгамування болю
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CN102093386B (zh) * 2011-01-05 2016-06-01 浙江华海药业股份有限公司 一种制备奥兰扎平晶型ⅱ的方法
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CN104755928B (zh) 2012-08-21 2017-05-10 詹森药业有限公司 奥氮平的抗体及其用途
CN104755093B (zh) * 2012-08-21 2018-11-16 詹森药业有限公司 奥氮平半抗原的抗体及其用途
JP6440625B2 (ja) 2012-11-14 2018-12-19 ザ・ジョンズ・ホプキンス・ユニバーシティー 精神分裂病を処置するための方法および組成物
CN103848847B (zh) * 2012-12-04 2018-02-06 广东东阳光药业有限公司 一种改进制备奥氮平及其晶型ii的方法
JP6008734B2 (ja) * 2012-12-20 2016-10-19 株式会社トクヤマ オランザピンｉｉ型結晶の製造方法
CN103145731B (zh) * 2013-02-26 2014-02-19 江苏豪森药业股份有限公司 奥氮平晶型及其制备方法和用途
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CN120569188A (zh) 2023-01-10 2025-08-29 美蒂森股份公司 奥氮平组合物和使用方法

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Also Published As

Publication number Publication date
GB2313835A (en) 1997-12-10
TW442488B (en) 2001-06-23
EA000149B1 (ru) 1998-10-29
KR19980703188A (ko) 1998-10-15
HU224989B1 (en) 2006-05-29
DK1445259T3 (da) 2006-10-16
DE69636313T2 (de) 2007-05-31
CZ300097A3 (en) 1997-12-17
AU706471B2 (en) 1999-06-17
AT406771B (de) 2000-08-25
SE9703205D0 (sv) 1997-09-05
PL322501A1 (en) 1998-02-02
YU49478B (sh) 2006-05-25
ZA962344B (en) 1997-09-22
CH690579A5 (de) 2000-10-31
EP1445259B1 (fr) 2006-06-28
ATE251627T1 (de) 2003-10-15
OA10510A (en) 2002-04-24
GB9719819D0 (en) 1997-11-19
SI9620040B (sl) 2002-02-28
JPH11502535A (ja) 1999-03-02
MY114701A (en) 2002-12-31
DE19681286T1 (de) 1998-04-02
UA44765C2 (uk) 2002-03-15
LT97148A (lt) 1998-01-26
NO314663B1 (no) 2003-04-28
DE69630324T2 (de) 2004-07-29
CN1065536C (zh) 2001-05-09
KR100399688B1 (ko) 2004-02-18
CO4650278A1 (es) 1998-09-03
LV12018A (lv) 1998-04-20
CA2214005C (fr) 2001-07-03
SI9620040A (sl) 1998-06-30
CA2214005A1 (fr) 1996-10-03
LV12018B (en) 1998-09-20
ATE204280T1 (de) 2001-09-15
HUP9802824A3 (en) 2000-01-28
EP0733635B1 (fr) 2001-08-16
AP9701065A0 (en) 1997-10-31
AR010448A1 (es) 2000-06-28
TR199701017T1 (xx) 1998-01-21
WO1996030375A1 (fr) 1996-10-03
AU5427996A (en) 1996-10-16
DK0733635T3 (da) 2001-10-08
NO974365L (no) 1997-09-22
EP1095941B1 (fr) 2003-10-08
DK1095941T3 (da) 2004-02-16
YU17796A (sh) 1999-03-04
IL117610A (en) 2001-08-26
AP828A (en) 2000-04-28
PE44897A1 (es) 1997-10-22
ATA902196A (de) 2000-01-15
HK1013988A1 (en) 1999-09-17
ZA962342B (en) 1997-09-22
PL183723B1 (pl) 2002-07-31
LU90096B1 (fr) 1997-07-22
IL117610A0 (en) 1996-07-23
DE69630324D1 (de) 2003-11-13
MX9707183A (es) 1997-11-29
FI973750A7 (fi) 1997-09-22
SK284143B6 (sk) 2004-10-05
LT4349B (lt) 1998-05-25
PT733635E (pt) 2001-12-28
SI1445259T1 (sl) 2006-10-31
IS4564A (is) 1997-09-22
IS1896B (is) 2003-10-20
DE69636313D1 (de) 2006-08-10
DE69614426D1 (de) 2001-09-20
EE03489B1 (et) 2001-08-15
ES2266719T3 (es) 2007-03-01
EA199700262A1 (ru) 1998-02-26
EP1445259A1 (fr) 2004-08-11
BG101900A (en) 1999-03-31
FI973750L (fi) 1997-09-22
DK108997A (da) 1997-11-12
SK121897A3 (en) 1998-03-04
ATE331719T1 (de) 2006-07-15
SV1996000031A (es) 1998-03-27
HUP9802824A2 (hu) 1999-06-28
BG62619B1 (bg) 2000-03-31
TW513432B (en) 2002-12-11
FI973750A0 (fi) 1997-09-22
ES2208220T3 (es) 2004-06-16
BR9607790A (pt) 1998-07-07
RO118872B1 (ro) 2003-12-30
ES2159346T3 (es) 2001-10-01
EE9700232A (et) 1998-04-15
SE9703205L (sv) 1997-09-05
CN1179160A (zh) 1998-04-15
CZ292688B6 (cs) 2003-11-12
GB2313835B (en) 1998-09-16
SI1095941T1 (en) 2003-12-31
NO974365D0 (no) 1997-09-22
AR002719A1 (es) 1998-04-29
NZ306110A (en) 1998-09-24
US5736541A (en) 1998-04-07
EP1095941A1 (fr) 2001-05-02
DE69614426T2 (de) 2002-05-23
PA8353701A1 (es) 1998-09-18
PT1445259E (pt) 2006-10-31
SI0733635T1 (en) 2002-06-30
PT1095941E (pt) 2004-02-27
EP0733635A1 (fr) 1996-09-25

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