ES2082481T3 - Procedimiento para la preparacion de intermedios de la sertralina. - Google Patents

Procedimiento para la preparacion de intermedios de la sertralina.

Info

Publication number
ES2082481T3
ES2082481T3 ES92914659T ES92914659T ES2082481T3 ES 2082481 T3 ES2082481 T3 ES 2082481T3 ES 92914659 T ES92914659 T ES 92914659T ES 92914659 T ES92914659 T ES 92914659T ES 2082481 T3 ES2082481 T3 ES 2082481T3
Authority
ES
Spain
Prior art keywords
preparation
sertraline
intermediates
procedure
stereoisometric
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92914659T
Other languages
English (en)
Inventor
Michael Trevelyan Williams
Willard Mckowan Welch Jr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PFIZER
Pfizer Inc
Original Assignee
PFIZER
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PFIZER, Pfizer Inc filed Critical PFIZER
Application granted granted Critical
Publication of ES2082481T3 publication Critical patent/ES2082481T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
    • C07C233/14—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a ring other than a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/23—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a ring other than a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LA INVENCION SUMINISTRA UNA FORMA TRANS-ESTEREOISOMETRICA, SUSTANCIALMENTE GEOMETRICAMENTE Y OPTICAMENTE PURA DE UN COMPUESTO DE LA FORMULA (I), EN DONDE E1 ES H O ALQUILO C1-C4, JUNTO CON PROCESOS PARA SU PREPARACION. LOS COMPUESTOS SON PRODUCTOS INTERMEDIOS PARA LA PREPARACION DE UN AGENTE ANTIDEPRESIVO CONOCIDO COMO SERTRALINA.
ES92914659T 1991-07-11 1992-07-03 Procedimiento para la preparacion de intermedios de la sertralina. Expired - Lifetime ES2082481T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919114948A GB9114948D0 (en) 1991-07-11 1991-07-11 Process for preparing sertraline intermediates

Publications (1)

Publication Number Publication Date
ES2082481T3 true ES2082481T3 (es) 1996-03-16

Family

ID=10698171

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92914659T Expired - Lifetime ES2082481T3 (es) 1991-07-11 1992-07-03 Procedimiento para la preparacion de intermedios de la sertralina.

Country Status (14)

Country Link
US (1) US5442116A (es)
EP (1) EP0595851B1 (es)
JP (1) JP2563754B2 (es)
AT (1) ATE132848T1 (es)
CA (1) CA2109818C (es)
DE (1) DE69207601T2 (es)
DK (1) DK0595851T3 (es)
ES (1) ES2082481T3 (es)
FI (1) FI112209B (es)
GB (1) GB9114948D0 (es)
GR (1) GR3019122T3 (es)
IE (1) IE71029B1 (es)
PT (1) PT100673B (es)
WO (1) WO1993001161A1 (es)

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CA2109818A1 (en) 1993-01-12
DK0595851T3 (da) 1996-02-12
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FI112209B (fi) 2003-11-14
US5442116A (en) 1995-08-15
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EP0595851B1 (en) 1996-01-10
FI940105L (fi) 1994-01-10
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DE69207601D1 (de) 1996-02-22
IE922249A1 (en) 1993-01-13
PT100673A (pt) 1993-09-30
CA2109818C (en) 2003-01-21
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ATE132848T1 (de) 1996-01-15

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