ES8200557A1 - Un procedimiento para la preparacion de una composicion farmaceutica de cesion sostenida de un producto medio solido. - Google Patents

Un procedimiento para la preparacion de una composicion farmaceutica de cesion sostenida de un producto medio solido.

Info

Publication number
ES8200557A1
ES8200557A1 ES493152A ES493152A ES8200557A1 ES 8200557 A1 ES8200557 A1 ES 8200557A1 ES 493152 A ES493152 A ES 493152A ES 493152 A ES493152 A ES 493152A ES 8200557 A1 ES8200557 A1 ES 8200557A1
Authority
ES
Spain
Prior art keywords
medical material
meta
solid medical
cellulose
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES493152A
Other languages
English (en)
Other versions
ES493152A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamanouchi Pharmaceutical Co Ltd
Original Assignee
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP8520979A external-priority patent/JPS5649314A/ja
Priority claimed from JP3651480A external-priority patent/JPS5948810B2/ja
Application filed by Yamanouchi Pharmaceutical Co Ltd filed Critical Yamanouchi Pharmaceutical Co Ltd
Publication of ES493152A0 publication Critical patent/ES493152A0/es
Publication of ES8200557A1 publication Critical patent/ES8200557A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO DE PRODUCCION DE UNA COMPOSICION FARMACEUTICA DE CESION SOSTENIDA DE UN MATERIAL MEDICO SOLIDO. CONSISTENTE EN DISOLVER UN MATERIAL MEDICO SOLIDO Y UNA O MAS SUSTANCIAS BASICAS SELECCIONADAS EN UN DISOLVENTE ORGANICO O AGUA, ELIMINANDOSE DESPUES EL DISOLVENTE POR SECADO A PRESION NORMAL O REDUCIDA, POR PULVERIZACION, LIOFILIZACION, ETC., CON LO QUE SE OBTIENE UN POLVO FINO O GRANULOS DE PARTICULAS FINAS EN LOS CUALES ESTA DISUELTO O DISPERSO UNIFORMEMENTE EL MATERIAL MEDICO EN FORMA AMORFA EN LA(S) SUSTANCIA(S) BASICA(S). DESPUES SE AÑADE OXIDO DE POLIETILENO, OBTENIENDOSE ASI LA COMPOSICION FARMACEUTICA DE CESION SOSTENIDA. COMO MATERIAL MEDICO SOLIDO PUEDE UTILIZARSE CUALQUIER MATERIAL MEDICO QUE TENGA BAJA O ALTA SOLUBILIDAD, SIEMPRE QUE SE DESEE MANTENERLO LARGO TIEMPO EN EL TRACTO GASTROENTERAL, COMO, POR EJEMPLO, HIDROCLORURO DE NICARDIPINA, NIFEDIPINA, INDENEROL, ETC.
ES493152A 1979-07-05 1980-07-04 Un procedimiento para la preparacion de una composicion farmaceutica de cesion sostenida de un producto medio solido. Expired ES8200557A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP8520979A JPS5649314A (en) 1979-07-05 1979-07-05 Lasting pharmaceutical composition having prolonged action and its preparation
JP3651480A JPS5948810B2 (ja) 1980-03-22 1980-03-22 ニカルジピン持続性製剤用組成物

Publications (2)

Publication Number Publication Date
ES493152A0 ES493152A0 (es) 1981-11-16
ES8200557A1 true ES8200557A1 (es) 1981-11-16

Family

ID=26375569

Family Applications (1)

Application Number Title Priority Date Filing Date
ES493152A Expired ES8200557A1 (es) 1979-07-05 1980-07-04 Un procedimiento para la preparacion de una composicion farmaceutica de cesion sostenida de un producto medio solido.

Country Status (9)

Country Link
US (3) US4343789A (es)
CA (1) CA1146866A (es)
CH (1) CH648484A5 (es)
DE (1) DE3024858C2 (es)
ES (1) ES8200557A1 (es)
FR (1) FR2460667A1 (es)
GB (1) GB2053681B (es)
IT (1) IT1132169B (es)
SE (1) SE448342B (es)

Families Citing this family (306)

* Cited by examiner, † Cited by third party
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Also Published As

Publication number Publication date
FR2460667A1 (fr) 1981-01-30
ES493152A0 (es) 1981-11-16
US4343789A (en) 1982-08-10
SE448342B (sv) 1987-02-16
US4673564A (en) 1987-06-16
DE3024858A1 (de) 1981-01-22
CA1146866A (en) 1983-05-24
GB2053681B (en) 1984-04-04
DE3024858C2 (de) 1996-02-29
CH648484A5 (de) 1985-03-29
IT8023228A0 (it) 1980-07-03
SE8004938L (sv) 1981-01-06
IT1132169B (it) 1986-06-25
FR2460667B1 (es) 1983-07-29
US4404183A (en) 1983-09-13
GB2053681A (en) 1981-02-11

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