NO20053368L - Fremgangsmate for fremstilling av en farmasoytisk ren polymorf I av olanzapin. - Google Patents

Fremgangsmate for fremstilling av en farmasoytisk ren polymorf I av olanzapin.

Info

Publication number: NO20053368L
Authority: NO; Norway
Prior art keywords: olanzapine; pharmaceutically pure; preparing; pure polymorph; methylene chloride
Prior art date: 2002-12-20

Application number

NO20053368A

Other languages

English (en)

Norwegian (no)

Other versions

NO20053368D0 (no

Inventor

Tomasz Stawinsky

Zbigniew Majka

Original Assignee

Adamed Sp Zoo

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-12-20

Filing date

2005-07-11

Publication date

2005-07-11

2005-07-11 Application filed by Adamed Sp Zoo filed Critical Adamed Sp Zoo

2005-07-11 Publication of NO20053368D0 publication Critical patent/NO20053368D0/no

2005-07-11 Publication of NO20053368L publication Critical patent/NO20053368L/no

Links

KVWDHTXUZHCGIO-UHFFFAOYSA-N olanzapine Chemical compound C1CN(C)CCN1C1=NC2=CC=CC=C2NC2=C1C=C(C)S2 KVWDHTXUZHCGIO-UHFFFAOYSA-N 0.000 title abstract 6
229960005017 olanzapine Drugs 0.000 title abstract 6
238000004519 manufacturing process Methods 0.000 title 1
YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 abstract 6
238000002425 crystallisation Methods 0.000 abstract 2
230000008025 crystallization Effects 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 abstract 1
-1 fli for Pollution S Chemical compound 0.000 abstract 1
238000002360 preparation method Methods 0.000 abstract 1
238000010992 reflux Methods 0.000 abstract 1
239000000741 silica gel Substances 0.000 abstract 1
229910002027 silica gel Inorganic materials 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

NO20053368A 2002-12-20 2005-07-11 Fremgangsmate for fremstilling av en farmasoytisk ren polymorf I av olanzapin. NO20053368L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
PL357928A PL202856B1 (pl)	2002-12-20	2002-12-20	Sposób otrzymywania farmaceutycznie czystej polimorficznej postaci I olanzapiny
PCT/IB2003/005931 WO2004056833A1 (en)	2002-12-20	2003-12-15	A process for the preparation of a pharmaceutically pure polymorphic form i of olanzapine

Publications (2)

Publication Number	Publication Date
NO20053368D0 NO20053368D0 (no)	2005-07-11
NO20053368L true NO20053368L (no)	2005-07-11

Family

ID=32678125

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20053368A NO20053368L (no)	2002-12-20	2005-07-11	Fremgangsmate for fremstilling av en farmasoytisk ren polymorf I av olanzapin.

Country Status (13)

Country	Link
EP (1)	EP1581537B1 (pl)
CN (1)	CN100354280C (pl)
AU (1)	AU2003292452A1 (pl)
BR (1)	BR0317594A (pl)
CA (1)	CA2506663A1 (pl)
DE (1)	DE60317712D1 (pl)
ES (1)	ES2294333T3 (pl)
HR (1)	HRP20050549A2 (pl)
MX (1)	MXPA05006711A (pl)
NO (1)	NO20053368L (pl)
PL (1)	PL202856B1 (pl)
UA (1)	UA82213C2 (pl)
WO (1)	WO2004056833A1 (pl)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2003300324A1 (en)	2002-12-24	2004-07-22	Teva Pharmaceutical Industries Ltd.	Novel crystal forms of olanzapine, methods for their preparation and method for the preparation of known olanzapine crystal forms
WO2006025065A1 (en) *	2004-08-31	2006-03-09	Lee Pharma Private Limited	A process for the preparation of anhydrous olanzopine hydrochloride of form-1
WO2006027800A1 (en)	2004-09-06	2006-03-16	Shasun Chemicals And Drugs Limited	A novel process for preparation of a pharmaceutically pure polymorphic form 1 of olanzapine
GB0522473D0 (en)	2005-11-03	2005-12-14	Actavis Group	A pharmaceutical formulation
WO2007144901A1 (en) *	2006-06-12	2007-12-21	Jubilant Organosys Limited	Process for stabilization of olanzapine polymorphic form i
PL381564A1 (pl)	2007-01-22	2008-08-04	Koźluk Tomasz Nobilus Ent	Sposób wytwarzania zasadniczo czystej odmiany polimorficznej I olanzapiny
EP2292624A1 (en)	2009-07-20	2011-03-09	LEK Pharmaceuticals d.d.	Process for the purification of olanzapine
CN103910747B (zh) *	2014-04-24	2016-03-23	东南大学	一种奥氮平药物晶型f及其制备方法
CN109456336A (zh) *	2017-09-06	2019-03-12	万全万特制药江苏有限公司	奥氮平的精制方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5229382A (en) *	1990-04-25	1993-07-20	Lilly Industries Limited	2-methyl-thieno-benzodiazepine
GB9009229D0 (en) *	1990-04-25	1990-06-20	Lilly Industries Ltd	Pharmaceutical compounds
EG23659A (en) *	1995-03-24	2007-03-26	Lilly Co Eli	Process and crystal forms of methyl-thieno-benzodiazepine
CR5278A (es) *	1995-03-24	1996-07-04	Lilly Co Eli	Formulacion oral de 2-metil-tieno-benzodiacepina
US5631250A (en) *	1995-03-24	1997-05-20	Eli Lilly And Company	Process and solvate of 2-methyl-thieno-benzodiazepine
US6348458B1 (en) *	1999-12-28	2002-02-19	U & I Pharmaceuticals Ltd.	Polymorphic forms of olanzapine
SK2502003A3 (en) *	2000-08-31	2004-03-02	Reddys Lab Ltd Dr	Process for preparation of hydrates of olanzapine and their conversion into crystalline forms of olanzapine
PL196814B1 (pl) *	2002-05-17	2008-02-29	Inst Farmaceutyczny	Sposób wytwarzania odmiany polimorficznej I olanzapiny i jej solwaty
ATE500258T1 (de) *	2002-05-31	2011-03-15	Sandoz Ag	Verfahren zur herstellung von olanzapin form i
SI21270A (sl) *	2002-07-15	2004-02-29	Krka, Tovarna Zdravil, D.D., Novo Mesto	Kristalne oblike olanzapina in postopki za njihovo pripravo

2002
- 2002-12-20 PL PL357928A patent/PL202856B1/pl unknown
2003
- 2003-12-15 BR BR0317594-4A patent/BR0317594A/pt not_active IP Right Cessation
- 2003-12-15 CN CNB200380106963XA patent/CN100354280C/zh not_active Expired - Fee Related
- 2003-12-15 UA UAA200507207A patent/UA82213C2/uk unknown
- 2003-12-15 ES ES03768031T patent/ES2294333T3/es not_active Expired - Lifetime
- 2003-12-15 MX MXPA05006711A patent/MXPA05006711A/es unknown
- 2003-12-15 HR HR20050549A patent/HRP20050549A2/hr not_active Application Discontinuation
- 2003-12-15 EP EP03768031A patent/EP1581537B1/en not_active Expired - Lifetime
- 2003-12-15 DE DE60317712T patent/DE60317712D1/de not_active Expired - Lifetime
- 2003-12-15 WO PCT/IB2003/005931 patent/WO2004056833A1/en not_active Ceased
- 2003-12-15 AU AU2003292452A patent/AU2003292452A1/en not_active Abandoned
- 2003-12-15 CA CA002506663A patent/CA2506663A1/en not_active Abandoned
2005
- 2005-07-11 NO NO20053368A patent/NO20053368L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
WO2004056833A1 (en)	2004-07-08
MXPA05006711A (es)	2005-11-23
NO20053368D0 (no)	2005-07-11
BR0317594A (pt)	2005-11-22
EP1581537B1 (en)	2007-11-21
PL357928A1 (pl)	2004-06-28
AU2003292452A1 (en)	2004-07-14
PL202856B1 (pl)	2009-07-31
ES2294333T3 (es)	2008-04-01
UA82213C2 (uk)	2008-03-25
CN100354280C (zh)	2007-12-12
HRP20050549A2 (en)	2005-12-31
CA2506663A1 (en)	2004-07-08
DE60317712D1 (de)	2008-01-03
EP1581537A1 (en)	2005-10-05
CN1729195A (zh)	2006-02-01

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Legal Events

Date	Code	Title	Description
2012-01-02	FC2A	Withdrawal, rejection or dismissal of laid open patent application