NO2012004I2 - l-okso-2-(2,6-dioksopiperidin-3-yl)-4-aminoisoindolin i racemisk form eller R-eller S-isomerer derav - Google Patents

l-okso-2-(2,6-dioksopiperidin-3-yl)-4-aminoisoindolin i racemisk form eller R-eller S-isomerer derav

Info

Publication number
NO2012004I2
NO2012004I2 NO2012004C NO2012004C NO2012004I2 NO 2012004 I2 NO2012004 I2 NO 2012004I2 NO 2012004 C NO2012004 C NO 2012004C NO 2012004 C NO2012004 C NO 2012004C NO 2012004 I2 NO2012004 I2 NO 2012004I2
Authority
NO
Norway
Prior art keywords
carbon atoms
hydrogen
alkyl
aminoisoindoline
dioxopiperidin
Prior art date
Application number
NO2012004C
Other languages
English (en)
Other versions
NO2012004I1 (no
Original Assignee
Celgene Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celgene Corp filed Critical Celgene Corp
Publication of NO2012004I1 publication Critical patent/NO2012004I1/no
Publication of NO2012004I2 publication Critical patent/NO2012004I2/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/45—Non condensed piperidines, e.g. piperocaine having oxo groups directly attached to the heterocyclic ring, e.g. cycloheximide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
NO2012004C 1997-05-30 2012-03-06 l-okso-2-(2,6-dioksopiperidin-3-yl)-4-aminoisoindolin i racemisk form eller R-eller S-isomerer derav NO2012004I2 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4827897P 1997-05-30 1997-05-30
PCT/US1998/010886 WO1998054170A1 (en) 1997-05-30 1998-05-28 SUBSTITUTED 2-(2,6-DIOXOPIPERIDIN-3-YL)-PHTHALIMIDES AND 1-OXOISOINDOLINES AND METHOD OF REDUCING TNFα LEVELS

Publications (2)

Publication Number Publication Date
NO2012004I1 NO2012004I1 (no) 2012-03-19
NO2012004I2 true NO2012004I2 (no) 2013-05-06

Family

ID=21953674

Family Applications (6)

Application Number Title Priority Date Filing Date
NO19995751A NO322080B1 (no) 1997-05-30 1999-11-23 2,6-dioksopiperidiner samt farmasoytiske preparater som inneholder disse.
NO20061455A NO331367B1 (no) 1997-05-30 2006-03-30 1-okso-2-(2,6 dioksopiperidin-3-yl)-4-aminoisoindolin samt farmasoytisk sammensetning inneholdende en slik forbindelse
NO20092860A NO332270B1 (no) 1997-05-30 2009-08-18 Farmasoytisk sammensetning som omfatter 1,3-diokso-2-(2,6-dioksopiperidin-3-yl)-4-aminoisoindolin og en farmasoytisk akseptabel eksipiens, fortynningsmiddel eller baerer
NO20111536A NO332271B1 (no) 1997-05-30 2011-11-08 2,6-dioksopiperidiner, anvendelse derav samt fremgangsmate for fremstilling av et medikament som inneholder en slik forbindelse
NO2012004C NO2012004I2 (no) 1997-05-30 2012-03-06 l-okso-2-(2,6-dioksopiperidin-3-yl)-4-aminoisoindolin i racemisk form eller R-eller S-isomerer derav
NO20120330A NO333641B1 (no) 1997-05-30 2012-03-20 2,6-dioksopiperidinderivater samt farmasoytiske preparater som inneholder disse

Family Applications Before (4)

Application Number Title Priority Date Filing Date
NO19995751A NO322080B1 (no) 1997-05-30 1999-11-23 2,6-dioksopiperidiner samt farmasoytiske preparater som inneholder disse.
NO20061455A NO331367B1 (no) 1997-05-30 2006-03-30 1-okso-2-(2,6 dioksopiperidin-3-yl)-4-aminoisoindolin samt farmasoytisk sammensetning inneholdende en slik forbindelse
NO20092860A NO332270B1 (no) 1997-05-30 2009-08-18 Farmasoytisk sammensetning som omfatter 1,3-diokso-2-(2,6-dioksopiperidin-3-yl)-4-aminoisoindolin og en farmasoytisk akseptabel eksipiens, fortynningsmiddel eller baerer
NO20111536A NO332271B1 (no) 1997-05-30 2011-11-08 2,6-dioksopiperidiner, anvendelse derav samt fremgangsmate for fremstilling av et medikament som inneholder en slik forbindelse

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO20120330A NO333641B1 (no) 1997-05-30 2012-03-20 2,6-dioksopiperidinderivater samt farmasoytiske preparater som inneholder disse

Country Status (24)

Country Link
US (3) US6395754B1 (no)
EP (3) EP0984955B1 (no)
JP (2) JP4307567B2 (no)
KR (1) KR100526212B1 (no)
CN (3) CN1258293A (no)
AT (2) ATE401319T1 (no)
AU (1) AU741982B2 (no)
CA (2) CA2291218C (no)
CY (1) CY1108348T1 (no)
CZ (1) CZ299812B6 (no)
DE (2) DE69825994T2 (no)
DK (2) DK0984955T3 (no)
ES (3) ES2229497T3 (no)
FI (1) FI19992490A7 (no)
HU (2) HU228769B1 (no)
MC (1) MC225A7 (no)
NO (6) NO322080B1 (no)
NZ (1) NZ501429A (no)
PL (1) PL193276B1 (no)
PT (2) PT1486496E (no)
RU (1) RU2209207C2 (no)
SK (1) SK163099A3 (no)
TR (4) TR200000107T2 (no)
WO (1) WO1998054170A1 (no)

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CN1258293A (zh) 2000-06-28
EP1486496A1 (en) 2004-12-15
TR200500299T2 (tr) 2005-06-21
KR100526212B1 (ko) 2005-11-03
EP0984955B1 (en) 2004-09-01
HU229578B1 (en) 2014-02-28

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