UA80573C2 - Piperazinyl and diazapanyl benzamides and benzthioamides - Google Patents
Piperazinyl and diazapanyl benzamides and benzthioamides Download PDFInfo
- Publication number
- UA80573C2 UA80573C2 UAA200504801A UA2005004801A UA80573C2 UA 80573 C2 UA80573 C2 UA 80573C2 UA A200504801 A UAA200504801 A UA A200504801A UA 2005004801 A UA2005004801 A UA 2005004801A UA 80573 C2 UA80573 C2 UA 80573C2
- Authority
- UA
- Ukraine
- Prior art keywords
- methanone
- phenyl
- ylmethylphenyl
- isopropylpiperazin
- piperazin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0459—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0463—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0465—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0468—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0468—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K51/047—Benzodiazepines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P11/02—Nasal agents, e.g. decongestants
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P11/06—Antiasthmatics
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
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- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Toxicology (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Anesthesiology (AREA)
- Addiction (AREA)
- Obesity (AREA)
- Child & Adolescent Psychology (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42049502P | 2002-10-23 | 2002-10-23 | |
| PCT/US2003/033343 WO2004037801A1 (en) | 2002-10-23 | 2003-10-21 | Piperazinyl and diazapanyl benzamides and benzthioamides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA80573C2 true UA80573C2 (en) | 2007-10-10 |
Family
ID=32176579
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200504801A UA80573C2 (en) | 2002-10-23 | 2003-10-21 | Piperazinyl and diazapanyl benzamides and benzthioamides |
Country Status (32)
| Country | Link |
|---|---|
| US (2) | US7414047B2 (es) |
| EP (1) | EP1558595B1 (es) |
| JP (1) | JP4596918B2 (es) |
| KR (1) | KR101067732B1 (es) |
| CN (1) | CN100558718C (es) |
| AR (1) | AR041697A1 (es) |
| AT (1) | ATE449766T1 (es) |
| AU (1) | AU2003301552B2 (es) |
| BR (1) | BRPI0315644B8 (es) |
| CA (1) | CA2504269C (es) |
| CR (1) | CR7807A (es) |
| CY (1) | CY1109924T1 (es) |
| DE (1) | DE60330269D1 (es) |
| DK (1) | DK1558595T3 (es) |
| EA (1) | EA009860B1 (es) |
| EG (1) | EG25097A (es) |
| ES (1) | ES2335584T3 (es) |
| HR (1) | HRP20050352B1 (es) |
| IL (1) | IL168207A (es) |
| ME (1) | ME00334B (es) |
| MX (2) | MX339074B (es) |
| MY (1) | MY140886A (es) |
| NO (1) | NO330741B1 (es) |
| NZ (2) | NZ539595A (es) |
| PL (1) | PL215454B1 (es) |
| PT (1) | PT1558595E (es) |
| RS (1) | RS51681B (es) |
| SI (1) | SI1558595T1 (es) |
| TW (1) | TWI352594B (es) |
| UA (1) | UA80573C2 (es) |
| WO (1) | WO2004037801A1 (es) |
| ZA (1) | ZA200504067B (es) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60330269D1 (de) | 2002-10-23 | 2010-01-07 | Janssen Pharmaceutica Nv | Piperazinyl- und diazapanylbenzamide und-benzothioamide |
| GB0324159D0 (en) * | 2003-10-15 | 2003-11-19 | Glaxo Group Ltd | Novel compounds |
| US7429659B2 (en) | 2004-03-31 | 2008-09-30 | Janssen Pharmaceutica N.V. | Furan compounds as histamine H3 modulators |
| CN1972914A (zh) * | 2004-03-31 | 2007-05-30 | 詹森药业有限公司 | 作为组胺h3受体配合体的非咪唑杂环化合物 |
| PL1948607T3 (pl) * | 2005-09-16 | 2010-09-30 | Janssen Pharmaceutica Nv | Cyklopropyloaminy jako modulatory receptora histaminowego H3 |
| NZ567357A (en) * | 2005-10-31 | 2011-05-27 | Janssen Pharmaceutica Nv | Novel processes for the preparation of piperazinyl and diazapanyl benzamide derivatives |
| BRPI0618076A2 (pt) | 2005-10-31 | 2011-08-16 | Janssen Pharmaceutica Nv | processos para a preparação de derivados de ciclopropil-amida |
| US7795426B2 (en) * | 2005-10-31 | 2010-09-14 | Janssen Pharmaceutica Nv | Processes for the preparation of cyclopropyl-amide derivatives |
| ES2381205T3 (es) * | 2005-11-10 | 2012-05-24 | Msd K.K. | Derivado espiro aza-sustituido |
| KR101372941B1 (ko) * | 2006-05-30 | 2014-03-14 | 얀센 파마슈티카 엔.브이. | 히스타민 h3 수용체 조절제로서의 치환된 피리딜 아미드 화합물 |
| CA2655604C (en) | 2006-06-23 | 2016-08-09 | Abbott Laboratories | Cyclopropyl amine derivatives |
| US9108948B2 (en) | 2006-06-23 | 2015-08-18 | Abbvie Inc. | Cyclopropyl amine derivatives |
| US20080045507A1 (en) * | 2006-06-29 | 2008-02-21 | Allison Brett D | Substituted benzamide modulators of the histamine h3 receptor |
| LT2121636T (lt) * | 2006-12-14 | 2017-05-10 | Janssen Pharmaceutica N.V. | Piperazinilo ir diazepanilo benzamido darinių gamybos būdas |
| US20090170869A1 (en) | 2007-09-06 | 2009-07-02 | Desmond John Best | Piperazine derivative having affinity for the histamine h3 receptor |
| AR068509A1 (es) * | 2007-09-19 | 2009-11-18 | Jerini Ag | Antagosnistas del receptor de bradiquinina b1 |
| BRPI0820481A2 (pt) | 2007-11-20 | 2015-06-16 | Janssen Pharmaceutica Nv | Composotos cicloalquilóxi e heterocicloalquilóxi piridina como moduladores do receptor de h3 de histamina |
| US20100130477A1 (en) * | 2008-11-25 | 2010-05-27 | Astrazeneca Ab | Spirocyclobutyl Piperidine Derivatives |
| AU2010226711B2 (en) * | 2009-03-18 | 2015-06-18 | Janssen Pharmaceutica Nv | Process for the preparation of histamine H3 receptor modulators |
| US9186353B2 (en) | 2009-04-27 | 2015-11-17 | Abbvie Inc. | Treatment of osteoarthritis pain |
| WO2012037258A1 (en) | 2010-09-16 | 2012-03-22 | Abbott Laboratories | Processes for preparing 1,2-substituted cyclopropyl derivatives |
| RU2700595C1 (ru) * | 2019-07-30 | 2019-09-18 | Общество с ограниченной ответственностью "Кью Эм Фарма" | Производное 3,6,9-триазатрициклотетрадекана и его применение для лечения депрессии |
| EP4251148A1 (en) | 2020-11-27 | 2023-10-04 | Richter Gedeon Nyrt. | Histamine h3 receptor antagonists/inverse agonists for the treatment of autism spectrum disorder |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3714179A (en) | 1970-09-08 | 1973-01-30 | Searle & Co | 1-alkyl-2-furfurylthioimidazoles and congeners |
| US3886160A (en) | 1972-09-28 | 1975-05-27 | Searle & Co | 2-(2-Methyl-5-nitro-1-imidazolyl) ethyl-2-thiopseudoureas |
| JPH0641455B2 (ja) * | 1984-12-10 | 1994-06-01 | 日産化学工業株式会社 | ピリダジノン誘導体 |
| JP2813747B2 (ja) | 1989-05-22 | 1998-10-22 | 富士写真フイルム株式会社 | 画像形成法 |
| US5030644A (en) | 1989-07-31 | 1991-07-09 | Merck & Co., Inc. | Imidazole compounds and their use as transglutaminase inhibitors |
| US5492891A (en) | 1991-09-05 | 1996-02-20 | Novo Nordisk A/S | Method for treatment of patients with chronic liver disease |
| US5569659A (en) | 1991-09-11 | 1996-10-29 | Mcneilab, Inc. | 4-arylpiperazines and 4-arylpiperidines |
| US5217986A (en) | 1992-03-26 | 1993-06-08 | Harbor Branch Oceanographic Institution, Inc. | Anti-allergy agent |
| US5352707A (en) * | 1992-03-26 | 1994-10-04 | Harbor Branch Oceanographic Institution, Inc. | Method for treating airway congestion |
| RU2124511C1 (ru) | 1993-05-14 | 1999-01-10 | Фармасьютикал Ко., Лтд | Производные пиперазина |
| US5681954A (en) | 1993-05-14 | 1997-10-28 | Daiichi Pharmaceutical Co., Ltd. | Piperazine derivatives |
| US5464788A (en) | 1994-03-24 | 1995-11-07 | Merck & Co., Inc. | Tocolytic oxytocin receptor antagonists |
| JPH10511356A (ja) | 1994-12-22 | 1998-11-04 | スミスクライン・ビーチャム・コーポレイション | フィブリノゲン受容体拮抗物質 |
| IL117149A0 (en) | 1995-02-23 | 1996-06-18 | Schering Corp | Muscarinic antagonists |
| US5889006A (en) | 1995-02-23 | 1999-03-30 | Schering Corporation | Muscarinic antagonists |
| JPH09294056A (ja) * | 1996-04-25 | 1997-11-11 | Mitsubishi Electric Corp | 半導体集積回路 |
| JPH1059954A (ja) | 1996-08-14 | 1998-03-03 | Takeda Chem Ind Ltd | 環状アミン誘導体およびそれを含んでなる医薬 |
| US5869479A (en) | 1997-08-14 | 1999-02-09 | Schering Corporation | Treatment of upper airway allergic responses |
| CN1278269A (zh) | 1997-11-07 | 2000-12-27 | 第一制药株式会社 | 哌嗪-环糊精复合体 |
| GB9803536D0 (en) | 1998-02-19 | 1998-04-15 | Black James Foundation | Histamine H,receptor ligands |
| EP0978512A1 (en) * | 1998-07-29 | 2000-02-09 | Societe Civile Bioprojet | Non-imidazole aryloxy (or arylthio) alkylamines as histamine H3-receptor antagonists and their therapeutic applications |
| ATE319696T1 (de) | 2000-08-08 | 2006-03-15 | Ortho Mcneil Pharm Inc | Nicht-imidazol aryloxyalkylamine als h3 rezeptor liganden |
| KR100852362B1 (ko) | 2000-08-08 | 2008-08-14 | 오르토-맥네일 파마슈티칼, 인코퍼레이티드 | 비-이미다졸 아릴옥시피페리딘 |
| US20030013733A1 (en) | 2000-09-22 | 2003-01-16 | Richard Apodaca | Octahydro-indolizine and quinolizine and hexahydro-pyrrolizine |
| WO2002076925A2 (en) | 2001-03-23 | 2002-10-03 | Eli Lilly And Company | Non-imidazole aryl alkylamines compounds as histamine h3 receptor antagonists, preparation and therapeutic uses |
| ATE449090T1 (de) | 2001-07-02 | 2009-12-15 | High Point Pharmaceuticals Llc | Substituierte piperazin- und diazepanderivate zur verwendung als histamin h3 rezeptormodulatoren |
| ATE450508T1 (de) | 2001-09-14 | 2009-12-15 | High Point Pharmaceuticals Llc | Substituierte piperidinen mit selektiver bindungsfähigkeit zu histamin h3-rezeptoren |
| EP1430027B1 (en) | 2001-09-14 | 2010-09-01 | High Point Pharmaceuticals, LLC | Novel aminoazetidine, -pyrrolidine and -piperidine derivatives |
| EP2243776A1 (en) | 2001-10-12 | 2010-10-27 | High Point Pharmaceuticals, LLC | Substituted piperidines and their use for the treatment of diseases related to the histamine H3 receptor |
| CA2469893A1 (en) | 2001-12-10 | 2003-06-19 | Ortho-Mcneil Pharmaceutical, Inc. | Phenylalkynes |
| WO2003055866A1 (en) * | 2001-12-21 | 2003-07-10 | Bayer Pharmaceuticals Corporation | Quinazoline and quinoline derivative compounds as inhibitors of prolylpeptidase, inducers of apoptosis and cancer treatment agents |
| DE10201240A1 (de) * | 2002-01-15 | 2003-07-24 | Bayer Ag | Substituierte Alkyluracile und ihre Verwendung |
| BR0306980A (pt) | 2002-02-01 | 2004-11-09 | Novo Nordisk As | Composto, uso de um composto, composição farmacêutica, e, método para o tratamento de distúrbios ou doenças relacionadas com o receptor de histamina h3 |
| DE60330269D1 (de) | 2002-10-23 | 2010-01-07 | Janssen Pharmaceutica Nv | Piperazinyl- und diazapanylbenzamide und-benzothioamide |
| WO2005035534A1 (ja) | 2003-10-08 | 2005-04-21 | Ono Pharmaceutical Co., Ltd. | 複素ビシクロ環および複素トリシクロ環化合物およびその医薬 |
| GB0324159D0 (en) | 2003-10-15 | 2003-11-19 | Glaxo Group Ltd | Novel compounds |
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2003
- 2003-10-21 DE DE60330269T patent/DE60330269D1/de not_active Expired - Lifetime
- 2003-10-21 UA UAA200504801A patent/UA80573C2/uk unknown
- 2003-10-21 AU AU2003301552A patent/AU2003301552B2/en not_active Ceased
- 2003-10-21 CN CNB2003801070529A patent/CN100558718C/zh not_active Expired - Fee Related
- 2003-10-21 WO PCT/US2003/033343 patent/WO2004037801A1/en not_active Ceased
- 2003-10-21 NZ NZ539595A patent/NZ539595A/en not_active IP Right Cessation
- 2003-10-21 NZ NZ576432A patent/NZ576432A/en not_active IP Right Cessation
- 2003-10-21 MX MX2009006222A patent/MX339074B/es unknown
- 2003-10-21 HR HRP20050352AA patent/HRP20050352B1/hr not_active IP Right Cessation
- 2003-10-21 PT PT03809596T patent/PT1558595E/pt unknown
- 2003-10-21 EA EA200500528A patent/EA009860B1/ru unknown
- 2003-10-21 KR KR1020057006864A patent/KR101067732B1/ko not_active Expired - Fee Related
- 2003-10-21 RS YU20050317A patent/RS51681B/sr unknown
- 2003-10-21 EP EP03809596A patent/EP1558595B1/en not_active Expired - Lifetime
- 2003-10-21 MX MXPA05004384A patent/MXPA05004384A/es active IP Right Grant
- 2003-10-21 PL PL376324A patent/PL215454B1/pl unknown
- 2003-10-21 AT AT03809596T patent/ATE449766T1/de active
- 2003-10-21 CA CA2504269A patent/CA2504269C/en not_active Expired - Lifetime
- 2003-10-21 BR BRPI0315644A patent/BRPI0315644B8/pt not_active IP Right Cessation
- 2003-10-21 ES ES03809596T patent/ES2335584T3/es not_active Expired - Lifetime
- 2003-10-21 SI SI200331757T patent/SI1558595T1/sl unknown
- 2003-10-21 US US10/690,115 patent/US7414047B2/en not_active Expired - Lifetime
- 2003-10-21 JP JP2004546967A patent/JP4596918B2/ja not_active Expired - Fee Related
- 2003-10-21 ME MEP-2008-495A patent/ME00334B/me unknown
- 2003-10-21 DK DK03809596.4T patent/DK1558595T3/da active
- 2003-10-22 AR ARP030103848A patent/AR041697A1/es active IP Right Grant
- 2003-10-22 MY MYPI20034029A patent/MY140886A/en unknown
- 2003-10-23 TW TW092129372A patent/TWI352594B/zh not_active IP Right Cessation
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2005
- 2005-04-20 EG EGNA2005000151 patent/EG25097A/xx active
- 2005-04-21 IL IL168207A patent/IL168207A/en active IP Right Grant
- 2005-04-22 CR CR7807A patent/CR7807A/es not_active Application Discontinuation
- 2005-05-10 NO NO20052278A patent/NO330741B1/no not_active IP Right Cessation
- 2005-05-19 ZA ZA200504067A patent/ZA200504067B/en unknown
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2007
- 2007-10-30 US US11/928,006 patent/US20080056991A1/en not_active Abandoned
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2010
- 2010-01-15 CY CY20101100040T patent/CY1109924T1/el unknown
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