BG62597B1 - Средство и метод за хормонална контрацепция и/или лечение наакне - Google Patents
Средство и метод за хормонална контрацепция и/или лечение наакне Download PDFInfo
- Publication number
- BG62597B1 BG62597B1 BG100671A BG10067196A BG62597B1 BG 62597 B1 BG62597 B1 BG 62597B1 BG 100671 A BG100671 A BG 100671A BG 10067196 A BG10067196 A BG 10067196A BG 62597 B1 BG62597 B1 BG 62597B1
- Authority
- BG
- Bulgaria
- Prior art keywords
- hormonal
- daily doses
- component
- components
- administration
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims description 12
- 208000002874 Acne Vulgaris Diseases 0.000 title claims description 4
- 206010000496 acne Diseases 0.000 title claims description 4
- 239000003433 contraceptive agent Substances 0.000 title description 10
- 239000000262 estrogen Substances 0.000 claims abstract description 21
- 230000016087 ovulation Effects 0.000 claims abstract description 20
- 229940088597 hormone Drugs 0.000 claims abstract description 10
- 239000005556 hormone Substances 0.000 claims abstract description 10
- 239000000583 progesterone congener Substances 0.000 claims abstract description 7
- 239000013543 active substance Substances 0.000 claims abstract description 4
- 230000000035 biogenic effect Effects 0.000 claims abstract description 4
- 230000003054 hormonal effect Effects 0.000 claims description 89
- 239000003795 chemical substances by application Substances 0.000 claims description 23
- 229940011871 estrogen Drugs 0.000 claims description 17
- 230000005906 menstruation Effects 0.000 claims description 10
- 230000001076 estrogenic effect Effects 0.000 claims description 5
- 230000003152 gestagenic effect Effects 0.000 claims description 4
- 229940125697 hormonal agent Drugs 0.000 claims description 4
- 238000004806 packaging method and process Methods 0.000 abstract description 5
- 230000005070 ripening Effects 0.000 abstract 1
- VOXZDWNPVJITMN-ZBRFXRBCSA-N 17β-estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 description 10
- 229930182833 estradiol Natural products 0.000 description 10
- 229960005309 estradiol Drugs 0.000 description 10
- 230000002254 contraceptive effect Effects 0.000 description 8
- IMONTRJLAWHYGT-ZCPXKWAGSA-N Norethindrone Acetate Chemical compound C1CC2=CC(=O)CC[C@@H]2[C@@H]2[C@@H]1[C@@H]1CC[C@](C#C)(OC(=O)C)[C@@]1(C)CC2 IMONTRJLAWHYGT-ZCPXKWAGSA-N 0.000 description 4
- RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Chemical class C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 description 4
- 230000035800 maturation Effects 0.000 description 3
- 229940079593 drug Drugs 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 230000029849 luteinization Effects 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 231100000957 no side effect Toxicity 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- BFPYWIDHMRZLRN-UHFFFAOYSA-N 17alpha-ethynyl estradiol Natural products OC1=CC=C2C3CCC(C)(C(CC4)(O)C#C)C4C3CCC2=C1 BFPYWIDHMRZLRN-UHFFFAOYSA-N 0.000 description 1
- TXHUMRBWIWWBGW-UHFFFAOYSA-N Estradiol undecylate Natural products C1CC2=CC(O)=CC=C2C2C1C1CCC(OC(=O)CCCCCCCCCC)C1(C)CC2 TXHUMRBWIWWBGW-UHFFFAOYSA-N 0.000 description 1
- BFPYWIDHMRZLRN-SLHNCBLASA-N Ethinyl estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 BFPYWIDHMRZLRN-SLHNCBLASA-N 0.000 description 1
- MPSOHXLZDRQABN-KOAPPJMKSA-N [(8r,9s,10r,13s,14s,17r)-17-ethynyl-13-methyl-3-oxo-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl] acetate;(8r,9s,13s,14s,17s)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol;(8r,9s,13s,14s,16r,17 Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1.OC1=CC=C2[C@H]3CC[C@](C)([C@H]([C@H](O)C4)O)[C@@H]4[C@@H]3CCC2=C1.C1CC2=CC(=O)CC[C@@H]2[C@@H]2[C@@H]1[C@@H]1CC[C@](C#C)(OC(=O)C)[C@@]1(C)CC2 MPSOHXLZDRQABN-KOAPPJMKSA-N 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 238000005352 clarification Methods 0.000 description 1
- UWFYSQMTEOIJJG-FDTZYFLXSA-N cyproterone acetate Chemical compound C1=C(Cl)C2=CC(=O)[C@@H]3C[C@@H]3[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@@](C(C)=O)(OC(=O)C)[C@@]1(C)CC2 UWFYSQMTEOIJJG-FDTZYFLXSA-N 0.000 description 1
- 229960004976 desogestrel Drugs 0.000 description 1
- RPLCPCMSCLEKRS-BPIQYHPVSA-N desogestrel Chemical compound C1CC[C@@H]2[C@H]3C(=C)C[C@](CC)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 RPLCPCMSCLEKRS-BPIQYHPVSA-N 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 201000006828 endometrial hyperplasia Diseases 0.000 description 1
- TXHUMRBWIWWBGW-GVGNIZHQSA-N estradiol undecylate Chemical compound C1CC2=CC(O)=CC=C2[C@@H]2[C@@H]1[C@@H]1CC[C@H](OC(=O)CCCCCCCCCC)[C@@]1(C)CC2 TXHUMRBWIWWBGW-GVGNIZHQSA-N 0.000 description 1
- 229950005281 estradiol undecylate Drugs 0.000 description 1
- 229960002568 ethinylestradiol Drugs 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- FJQXCDYVZAHXNS-UHFFFAOYSA-N methadone hydrochloride Chemical compound Cl.C=1C=CC=CC=1C(CC(C)N(C)C)(C(=O)CC)C1=CC=CC=C1 FJQXCDYVZAHXNS-UHFFFAOYSA-N 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 229960001652 norethindrone acetate Drugs 0.000 description 1
- 230000027758 ovulation cycle Effects 0.000 description 1
- 230000000624 ovulatory effect Effects 0.000 description 1
- 239000000186 progesterone Substances 0.000 description 1
- 229960003387 progesterone Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Dermatology (AREA)
- Gynecology & Obstetrics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4344405A DE4344405C2 (de) | 1993-12-24 | 1993-12-24 | Ovulationshemmendes Mittel und Verfahren zur hormonalen Kontrazeption |
| PCT/DE1994/001420 WO1995017895A1 (de) | 1993-12-24 | 1994-11-24 | Mittel und verfahren zur hormonalen kontrazeption und/oder zur aknebehandlung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BG100671A BG100671A (bg) | 1997-04-30 |
| BG62597B1 true BG62597B1 (bg) | 2000-03-31 |
Family
ID=6506160
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG100671A BG62597B1 (bg) | 1993-12-24 | 1996-06-21 | Средство и метод за хормонална контрацепция и/или лечение наакне |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US5662927A (pl) |
| EP (1) | EP0735881B1 (pl) |
| JP (1) | JPH09502733A (pl) |
| KR (1) | KR960706344A (pl) |
| AT (1) | ATE247969T1 (pl) |
| AU (1) | AU703064B2 (pl) |
| BG (1) | BG62597B1 (pl) |
| BR (1) | BR9408513A (pl) |
| CA (1) | CA2179422A1 (pl) |
| CZ (1) | CZ186096A3 (pl) |
| DE (2) | DE4344405C2 (pl) |
| ES (1) | ES2206487T3 (pl) |
| FI (1) | FI962559A0 (pl) |
| HU (1) | HUT74428A (pl) |
| NO (1) | NO309843B1 (pl) |
| NZ (1) | NZ276370A (pl) |
| PL (1) | PL182544B1 (pl) |
| RU (1) | RU2169566C2 (pl) |
| SK (1) | SK79596A3 (pl) |
| WO (1) | WO1995017895A1 (pl) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4429374C1 (de) * | 1994-08-12 | 1996-02-01 | Jenapharm Gmbh | Pharmazeutische Präparate zur Kontrazeption/Hormonsubstitution mit biogener Estrogenkomponente |
| DE19513662A1 (de) * | 1995-04-08 | 1996-10-10 | Schering Ag | Pharmazeutisches Kombinationspräparat zur hormonalen Kontrazeption |
| DE19525017A1 (de) * | 1995-06-28 | 1997-01-02 | Schering Ag | Pharmazeutisches Kombinatonspräparat, Kit und Methode zur hormonalen Kontrazeption |
| DE19531936A1 (de) * | 1995-08-17 | 1997-02-20 | Schering Ag | Kombinationspräparat zur Kontrazeption, Kits diese enthaltend und eine Methode diese verwendend |
| US5922349A (en) * | 1995-09-28 | 1999-07-13 | Schering Aktiengesellschaft | Hormone replacement therapy method and hormone dispenser |
| DE60217324T2 (de) | 2001-05-18 | 2007-04-26 | Pantarhei Bioscience B.V. | Pharmazeutische zusammensetzung für die hormonersatztherapie |
| EP1260225A1 (en) * | 2001-05-18 | 2002-11-27 | Pantarhei Bioscience B.V. | A pharmaceutical composition for use in hormone replacement therapy |
| EP1390041B1 (en) | 2001-05-23 | 2009-11-25 | Pantarhei Bioscience B.V. | Drug delivery system comprising a tetrahydroxylated estrogen for use in hormonal contraception |
| US7732430B2 (en) | 2001-05-23 | 2010-06-08 | Pantarhei Bioscience B.V. | Drug delivery system comprising a tetrahydroxilated estrogen for use in hormonal contraception |
| ATE254465T1 (de) * | 2001-05-23 | 2003-12-15 | Pantarhei Bioscience Bv | Zubereitungen für die hormonale kontrazeption |
| ATE347365T1 (de) * | 2001-11-15 | 2006-12-15 | Pantarhei Bioscience Bv | Verwendung von öestrogen in kombination mit progestogen für die hormonsubstitutions-therapie |
| MXPA04005445A (es) * | 2001-12-05 | 2005-03-23 | Barr Lab Inc | Anticonceptivos orales para prevenir el embarazo y disminuir la sintomatologia premenstrual. |
| CA2489270C (en) | 2002-06-11 | 2012-08-07 | Pantarhei Bioscience B.V. | A method of treating human skin and a skin care composition for use in such a method |
| AU2003274946A1 (en) | 2002-06-11 | 2003-12-22 | Pantarhei Bioscience B.V. | Method of treating or preventing immune mediated disorders and pharmaceutical formulation for use therein |
| US9034854B2 (en) | 2002-07-12 | 2015-05-19 | Pantarhei Bioscience B.V. | Pharmaceutical composition comprising estetrol derivatives for use in cancer therapy |
| US8987240B2 (en) | 2002-10-23 | 2015-03-24 | Pantarhei Bioscience B.V. | Pharmaceutical compositions comprising estetrol derivatives for use in cancer therapy |
| NZ585546A (en) * | 2003-07-16 | 2011-10-28 | Teva Womens Health Inc | Methods of hormonal treatment utilizing contraceptive regimens with continuous estrogen administration |
| RU2252014C1 (ru) * | 2003-12-23 | 2005-05-20 | Государственное образовательное учреждение высшего профессионального образования Московская медицинская академия им. И.М. Сеченова | Способ выбора терапии акне |
| EP1550447A1 (en) * | 2004-01-02 | 2005-07-06 | Schering Aktiengesellschaft | Menstrual cycle control and improvement of conception rates in females |
| US20070111975A1 (en) | 2004-10-07 | 2007-05-17 | Duramed Pharmaceuticals, Inc. | Methods of Hormonal Treatment Utilizing Ascending-Dose Extended Cycle Regimens |
| CN101583363B (zh) | 2007-01-08 | 2013-08-21 | 潘塔希生物科学股份有限公司 | 治疗或预防雌性哺乳动物不育症的方法和此类方法中使用的药物试剂盒 |
| EP2383279A1 (en) | 2011-07-19 | 2011-11-02 | Pantarhei Bioscience B.V. | Process for the preparation of estetrol |
| RS62297B1 (sr) | 2011-11-23 | 2021-09-30 | Therapeuticsmd Inc | Prirodne kombinovane hormonske supstitucione formulacije i terapije |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| RU2016143081A (ru) | 2014-05-22 | 2018-06-26 | Терапьютиксмд, Инк. | Натуральные комбинированные гормонозаместительные составы и терапии |
| RS57328B1 (sr) | 2015-06-18 | 2018-08-31 | Mithra Pharmaceuticals S A | Orodisperzibilna dozna jedinica koja sadrži estetrolsku komponentu |
| WO2016203044A1 (en) | 2015-06-18 | 2016-12-22 | Mithra Pharmaceuticals S.A. | Orodispersible tablet containing estetrol |
| LT3310345T (lt) | 2015-06-18 | 2021-06-25 | Estetra Sprl | Burnoje disperguojama tabletė, turinti estetrolio |
| NZ737945A (en) | 2015-06-18 | 2023-06-30 | Estetra Sprl | Orodispersible dosage unit containing an estetrol component |
| US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
| US9931349B2 (en) | 2016-04-01 | 2018-04-03 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical composition |
| US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
| CA3041016C (en) | 2016-10-28 | 2023-09-05 | Estetra Sprl | Method for the management of dysmenorrhea and menstrual pain |
| CA3178291A1 (en) | 2016-08-05 | 2018-04-12 | Estetra Srl | Method for the management of dysmenorrhea and menstrual pain |
| UA126746C2 (uk) | 2018-02-07 | 2023-01-18 | Естетра Спрл | Композиція контрацептива зі зниженими ефектами щодо серцево-судинної системи |
| CR20200486A (es) | 2018-04-19 | 2021-01-27 | Estetra Sprl | Compuestos y sus usos para aliviar los síntomas asociados a la menopausa |
| TWI801561B (zh) | 2018-04-19 | 2023-05-11 | 比利時商依思特拉私人有限責任公司 | 化合物及其用於緩解絕經相關症狀的用途 |
| US11633405B2 (en) | 2020-02-07 | 2023-04-25 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical formulations |
| TWI893101B (zh) | 2020-04-16 | 2025-08-11 | 比利時商埃斯特拉有限責任公司 | 具有降低之副作用之避孕組成物 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3733407A (en) * | 1971-08-25 | 1973-05-15 | Syntex Corp | Menopause treatment |
| US4183924A (en) * | 1978-02-27 | 1980-01-15 | Schering Corporation | 17α-Chloro-17β-hydrocarbonsulfinyl-1,4-androstadienes and the corresponding 17β-hydrocarbonsulfonyl derivatives and their use as anti-acne agents |
| US4921843A (en) * | 1988-10-20 | 1990-05-01 | Pasquale Samuel A | Contraception system and method |
| DE4104385C1 (pl) * | 1991-02-09 | 1992-08-13 | Marika Dr.Med. 6509 Framersheim De Ehrlich | |
| DE4224534A1 (de) * | 1992-07-24 | 1994-01-27 | Marika Dr Med Ehrlich | Ovulationshemmendes Mittel zur hormonalen Kontrazeption |
| DE4308406C1 (de) * | 1993-03-12 | 1994-06-16 | Jenapharm Gmbh | Kombinationspräparat zur Kontrazeption |
| DE4313926A1 (de) * | 1993-04-28 | 1994-11-03 | Jenapharm Gmbh | Pharmazeutisches Mehrphasenpräparat zur hormonalen Kontrazeption |
-
1993
- 1993-12-24 DE DE4344405A patent/DE4344405C2/de not_active Expired - Fee Related
-
1994
- 1994-11-24 HU HU9601714A patent/HUT74428A/hu unknown
- 1994-11-24 AU AU10625/95A patent/AU703064B2/en not_active Ceased
- 1994-11-24 NZ NZ276370A patent/NZ276370A/en unknown
- 1994-11-24 CA CA002179422A patent/CA2179422A1/en not_active Abandoned
- 1994-11-24 AT AT95901345T patent/ATE247969T1/de not_active IP Right Cessation
- 1994-11-24 DE DE59410318T patent/DE59410318D1/de not_active Expired - Fee Related
- 1994-11-24 PL PL94315119A patent/PL182544B1/pl unknown
- 1994-11-24 BR BR9408513A patent/BR9408513A/pt not_active Application Discontinuation
- 1994-11-24 ES ES95901345T patent/ES2206487T3/es not_active Expired - Lifetime
- 1994-11-24 JP JP7517714A patent/JPH09502733A/ja active Pending
- 1994-11-24 EP EP95901345A patent/EP0735881B1/de not_active Expired - Lifetime
- 1994-11-24 KR KR1019960703246A patent/KR960706344A/ko not_active Ceased
- 1994-11-24 CZ CZ961860A patent/CZ186096A3/cs unknown
- 1994-11-24 RU RU96115165/14A patent/RU2169566C2/ru active
- 1994-11-24 SK SK795-96A patent/SK79596A3/sk unknown
- 1994-11-24 WO PCT/DE1994/001420 patent/WO1995017895A1/de not_active Ceased
- 1994-12-21 US US08/360,297 patent/US5662927A/en not_active Expired - Fee Related
-
1996
- 1996-06-19 FI FI962559A patent/FI962559A0/fi unknown
- 1996-06-21 NO NO962663A patent/NO309843B1/no not_active IP Right Cessation
- 1996-06-21 BG BG100671A patent/BG62597B1/bg unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO309843B1 (no) | 2001-04-09 |
| WO1995017895A1 (de) | 1995-07-06 |
| PL315119A1 (en) | 1996-10-14 |
| CA2179422A1 (en) | 1995-07-06 |
| DE59410318D1 (de) | 2003-10-02 |
| HUT74428A (en) | 1996-12-30 |
| RU2169566C2 (ru) | 2001-06-27 |
| DE4344405C2 (de) | 1995-12-07 |
| DE4344405A1 (de) | 1995-06-29 |
| ES2206487T3 (es) | 2004-05-16 |
| CZ186096A3 (en) | 1997-06-11 |
| AU703064B2 (en) | 1999-03-11 |
| EP0735881B1 (de) | 2003-08-27 |
| BR9408513A (pt) | 1997-08-19 |
| PL182544B1 (pl) | 2002-01-31 |
| US5662927A (en) | 1997-09-02 |
| NO962663L (no) | 1996-08-21 |
| FI962559A7 (fi) | 1996-06-19 |
| AU1062595A (en) | 1995-07-17 |
| NO962663D0 (no) | 1996-06-21 |
| KR960706344A (ko) | 1996-12-09 |
| SK79596A3 (en) | 1997-01-08 |
| NZ276370A (en) | 1997-06-24 |
| EP0735881A1 (de) | 1996-10-09 |
| FI962559A0 (fi) | 1996-06-19 |
| ATE247969T1 (de) | 2003-09-15 |
| HU9601714D0 (en) | 1996-08-28 |
| JPH09502733A (ja) | 1997-03-18 |
| BG100671A (bg) | 1997-04-30 |
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