DE69730217T2 - Dha-pharmazeutisches produkt konjugate - Google Patents

Dha-pharmazeutisches produkt konjugate Download PDF

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Publication number
DE69730217T2
DE69730217T2 DE69730217T DE69730217T DE69730217T2 DE 69730217 T2 DE69730217 T2 DE 69730217T2 DE 69730217 T DE69730217 T DE 69730217T DE 69730217 T DE69730217 T DE 69730217T DE 69730217 T2 DE69730217 T2 DE 69730217T2
Authority
DE
Germany
Prior art keywords
taxol
conjugate
conjugates
dha
tissue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69730217T
Other languages
German (de)
English (en)
Other versions
DE69730217D1 (de
Inventor
O. Matthews BRADLEY
E. Victor SHASHOUA
L. Nigel WEBB
S. Charles SWINDELL
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
American Regent Inc
Original Assignee
Luitpold Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Luitpold Pharmaceuticals Inc filed Critical Luitpold Pharmaceuticals Inc
Application granted granted Critical
Publication of DE69730217D1 publication Critical patent/DE69730217D1/de
Publication of DE69730217T2 publication Critical patent/DE69730217T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Epoxy Compounds (AREA)
  • Medicinal Preparation (AREA)
DE69730217T 1996-05-22 1997-05-22 Dha-pharmazeutisches produkt konjugate Expired - Lifetime DE69730217T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US651312 1996-05-22
US08/651,312 US5795909A (en) 1996-05-22 1996-05-22 DHA-pharmaceutical agent conjugates of taxanes
PCT/US1997/008867 WO1997044063A2 (en) 1996-05-22 1997-05-22 Dha-pharmaceutical agent conjugates

Publications (2)

Publication Number Publication Date
DE69730217D1 DE69730217D1 (de) 2004-09-16
DE69730217T2 true DE69730217T2 (de) 2005-07-28

Family

ID=24612392

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69730217T Expired - Lifetime DE69730217T2 (de) 1996-05-22 1997-05-22 Dha-pharmazeutisches produkt konjugate

Country Status (10)

Country Link
US (3) US5795909A (2)
EP (2) EP0909183B1 (2)
JP (1) JP4402173B2 (2)
AT (1) ATE273025T1 (2)
AU (1) AU725759B2 (2)
CA (1) CA2255614C (2)
DE (1) DE69730217T2 (2)
DK (1) DK0909183T3 (2)
ES (1) ES2222514T3 (2)
WO (1) WO1997044063A2 (2)

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EP0909183A2 (en) 1999-04-21
EP1466628A1 (en) 2004-10-13
CA2255614A1 (en) 1997-11-27
EP0909183B1 (en) 2004-08-11
WO1997044063A3 (en) 1998-02-26
US6602902B2 (en) 2003-08-05
AU725759B2 (en) 2000-10-19
US20020010208A1 (en) 2002-01-24
US7199151B2 (en) 2007-04-03
AU3142597A (en) 1997-12-09
US5795909A (en) 1998-08-18
JP4402173B2 (ja) 2010-01-20
DK0909183T3 (da) 2004-12-20
US20040180949A1 (en) 2004-09-16
JP2000514405A (ja) 2000-10-31
DE69730217D1 (de) 2004-09-16
WO1997044063A2 (en) 1997-11-27
CA2255614C (en) 2009-12-15
ES2222514T3 (es) 2005-02-01

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