DK0734393T3 - Fremgangsmåde til oprensning af polypeptider - Google Patents
Fremgangsmåde til oprensning af polypeptiderInfo
- Publication number
- DK0734393T3 DK0734393T3 DK95903202T DK95903202T DK0734393T3 DK 0734393 T3 DK0734393 T3 DK 0734393T3 DK 95903202 T DK95903202 T DK 95903202T DK 95903202 T DK95903202 T DK 95903202T DK 0734393 T3 DK0734393 T3 DK 0734393T3
- Authority
- DK
- Denmark
- Prior art keywords
- silica particles
- polypeptide
- mixture
- polypeptides
- purification
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/521—Chemokines
- C07K14/523—Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1, LDCF-2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4743—Insulin-like growth factor binding protein
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Analytical Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/166,337 US5451660A (en) | 1993-12-13 | 1993-12-13 | Method for purifying polypeptides |
| PCT/US1994/013983 WO1995016701A1 (en) | 1993-12-13 | 1994-12-06 | Method for purifying polypeptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0734393T3 true DK0734393T3 (da) | 2000-07-10 |
Family
ID=22602848
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK95903202T DK0734393T3 (da) | 1993-12-13 | 1994-12-06 | Fremgangsmåde til oprensning af polypeptider |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5451660A (da) |
| EP (1) | EP0734393B1 (da) |
| JP (1) | JP3843373B2 (da) |
| AT (1) | ATE178612T1 (da) |
| CA (1) | CA2177575C (da) |
| DE (1) | DE69417765T2 (da) |
| DK (1) | DK0734393T3 (da) |
| ES (1) | ES2131797T3 (da) |
| WO (1) | WO1995016701A1 (da) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0779927A1 (en) * | 1994-09-08 | 1997-06-25 | Chiron Corporation | A method of improved production of insulin-like growth factor |
| US6756484B1 (en) | 1995-04-14 | 2004-06-29 | Cephalon, Inc. | IGF-I purification process |
| US5650496A (en) * | 1995-04-14 | 1997-07-22 | Cephalon, Inc. | IGF-I purification process |
| AU6167596A (en) * | 1995-06-07 | 1996-12-30 | Chiron Corporation | Methods for purifying authentic igf from yeast hosts |
| US7071313B1 (en) | 1995-06-07 | 2006-07-04 | Cephalon, Inc. | Methods of purifying authentic IGF from yeast hosts |
| US7193042B1 (en) | 1995-06-07 | 2007-03-20 | Chiron Corporation | Methods for purifying authentic IGF from yeast hosts |
| US20040086494A1 (en) * | 1996-10-07 | 2004-05-06 | John Constance Mary | Immune privileged cells for delivery of proteins and peptides |
| AU729459B2 (en) * | 1996-11-15 | 2001-02-01 | Genentech Inc. | Purification of neurotrophins |
| DE69738075T2 (de) * | 1996-11-27 | 2008-05-21 | Genentech, Inc., South San Francisco | Affinitätsreinigung von polypeptiden an einer protein a-matrix |
| TW541179B (en) * | 1997-03-19 | 2003-07-11 | Green Cross Corp | Process for preparing immunoglobulin preparation |
| US6265542B1 (en) | 1997-10-24 | 2001-07-24 | Genentech, Inc. | Purification of molecules |
| US6121421A (en) * | 1998-08-21 | 2000-09-19 | Abbott Laboratories | Methods for isolating recombinant β-casein |
| US7399751B2 (en) * | 1999-11-04 | 2008-07-15 | Sertoli Technologies, Inc. | Production of a biological factor and creation of an immunologically privileged environment using genetically altered Sertoli cells |
| KR100356140B1 (ko) * | 1999-07-08 | 2002-10-19 | 한미약품공업 주식회사 | 인간 과립구 콜로니 자극인자 변이체 및 이의 생산 방법 |
| EP1401808B1 (en) | 2001-05-24 | 2009-07-08 | Neuren Pharmaceuticals Limited | Gpe analogs and peptidomimetics |
| US7714020B2 (en) * | 2001-05-24 | 2010-05-11 | Neuren Pharmaceuticals Limited | Treatment of non-convulsive seizures in brain injury using G-2-methyl-prolyl glutamate |
| US20070004641A1 (en) * | 2001-05-24 | 2007-01-04 | Neuren Pharmaceuticals Limited | Cognitive enhancement and cognitive therapy using glycyl-L-2-methylprolyl-L-glutamate |
| US7605177B2 (en) * | 2001-05-24 | 2009-10-20 | Neuren Pharmaceuticals Limited | Effects of glycyl-2 methyl prolyl glutamate on neurodegeneration |
| KR100436655B1 (ko) * | 2001-07-25 | 2004-06-22 | (주)엘피스바이오텍 | 광범위한 단백질에 적용할 수 있는 단백질의 농축 및정제 방법 |
| US7157276B2 (en) * | 2003-06-20 | 2007-01-02 | Biogen Idec Inc. | Use of depth filtration in series with continuous centrifugation to clarify mammalian cell cultures |
| CA2531022C (en) * | 2003-07-03 | 2014-09-09 | Jannette Dufour | Compositions containing sertoli cells and myoid cells and use thereof in cellular transplants |
| DK1969007T3 (da) * | 2005-12-20 | 2013-11-25 | Bristol Myers Squibb Co | Sammensætninger og fremgangsmåder til fremstilling af en sammensætning |
| AR058568A1 (es) | 2005-12-20 | 2008-02-13 | Bristol Myers Squibb Co | Metodos para producir una composicion con moleculas ctla4-ig a partir de un medio de cultivo |
| WO2008106043A2 (en) * | 2007-02-26 | 2008-09-04 | Alltech Associates Inc. | Ultra-fast chromatography |
| ES2657055T3 (es) * | 2007-08-09 | 2018-03-01 | Wyeth Llc | Uso de perfusión para mejorar la producción de un cultivo de células alimentado por lotes en biorreactores |
| JP5397800B2 (ja) * | 2008-07-31 | 2014-01-22 | 国立大学法人広島大学 | タンパク質の精製方法 |
| US8846878B1 (en) * | 2009-01-23 | 2014-09-30 | Cubrc Corporation | Method and device for isolating a protein sample |
| KR101382404B1 (ko) * | 2012-01-04 | 2014-04-14 | 대한민국 | 봉독의 대량 정제방법 |
| KR101504824B1 (ko) | 2013-05-31 | 2015-03-23 | 씨제이헬스케어 주식회사 | 고당화된 지속형 인간 성장호르몬 단백질 및 이의 제조방법 |
| US9902753B2 (en) | 2012-06-05 | 2018-02-27 | Cj Healthcare Corporation | Method of purifying a long-acting human growth hormone |
| KR101460266B1 (ko) | 2012-06-05 | 2014-11-11 | 씨제이헬스케어 주식회사 | 신규한 지속형 인간 성장호르몬의 정제 방법 |
| JP6110611B2 (ja) * | 2012-07-18 | 2017-04-05 | 株式会社東芝 | アミンの回収方法および分析方法 |
| EP2812091B1 (en) | 2012-09-17 | 2021-03-10 | W.R. Grace & CO. - CONN. | Chromatography media and devices |
| EP2811983B1 (en) | 2012-09-17 | 2019-05-01 | W.R. Grace & CO. - CONN. | Functionalized particulate support material and methods of making and using the same |
| ES2887110T3 (es) | 2014-01-16 | 2021-12-21 | Grace W R & Co | Medios para cromatografía de afinidad y dispositivos para cromatografía |
| PL3137209T3 (pl) | 2014-05-02 | 2023-01-02 | W.R. Grace & Co. - Conn. | Funkcjonalizowany materiał nośnikowy i sposoby wytwarzania oraz stosowania funkcjonalizowanego materiału nośnikowego |
| KR102566292B1 (ko) | 2015-06-05 | 2023-08-10 | 더블유.알. 그레이스 앤드 캄파니-콘. | 흡착성 바이오프로세싱 정화제와 이의 제조 및 사용 방법 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE295872C (da) * | ||||
| CH187815A (fr) * | 1936-05-01 | 1936-11-30 | Henri Dr Paschoud | Appareil d'éclairage d'un champ opératoire. |
| CH243336A (de) * | 1945-02-12 | 1946-07-15 | Ag Sandoz | Verfahren zur Herstellung eines metallisierbaren Disazofarbstoffes. |
| US3904751A (en) * | 1970-12-22 | 1975-09-09 | Behringwerke Ag | Process for isolating a fibrin stabilizing factor from human placenta |
| JPS5620287B2 (da) * | 1972-06-19 | 1981-05-13 | ||
| US3869482A (en) * | 1972-07-31 | 1975-03-04 | Etapharm Chem Pharm Lab G M B | Method of producing highly purified phosphatides |
| JPS5224594B2 (da) * | 1974-02-25 | 1977-07-01 | ||
| JPS51118810A (en) * | 1975-04-10 | 1976-10-19 | Fujiwa Kako Kk | A process for preparing proteolytic enzyme inhibitor from human urine |
| SU560614A1 (ru) * | 1976-02-11 | 1977-06-05 | Среднеазиатский Научно-Исследовательский И Проектно-Конструкторский Институт Пищевой Промышленности | Способ получени фосфолипазы д |
| FR2422720A2 (fr) * | 1977-04-26 | 1979-11-09 | Elf Aquitaine | Separation et purification de proteines par chromatographie |
| DE3147842A1 (de) * | 1981-12-03 | 1983-06-23 | Hoechst Ag, 6230 Frankfurt | "verfahren zur trennung von gemischen aus insulin, insulinderivaten und gegebenenfalls verunreinigungen" |
| DD209187A1 (de) * | 1982-09-08 | 1984-04-25 | Adw Ddr | Verfahren zur gewinnung von ergosterol und ubichinonen |
| JPS59159753A (ja) * | 1983-03-02 | 1984-09-10 | T Hasegawa Co Ltd | 風味改良剤の製法 |
| DD217823A1 (de) * | 1983-07-28 | 1985-01-23 | Adw Ddr | Verfahren zur gewinnung von erythrogenem toxin typ c |
| JPS60197629A (ja) * | 1984-03-16 | 1985-10-07 | Chemo Sero Therapeut Res Inst | HBs抗原の精製方法 |
| US5028531A (en) * | 1984-03-19 | 1991-07-02 | Fujisawa Pharmaceutical Company, Ltd. | IGF-I fusion proteins; protection of IGF-I from degradation by host cell; and processes for the production thereof |
| US4652529A (en) * | 1984-10-02 | 1987-03-24 | Syntex (U.S.A.) Inc. | Serum pretreatment for tricyclic antidepressant drug assays |
| DD280174A1 (de) * | 1985-04-24 | 1990-06-27 | Akad Wissenschaften Ddr | Verfahren zur beseitigung von immunglobulinaggregaten in immunglobulinpraeparaten |
| SU1272227A1 (ru) * | 1985-10-04 | 1986-11-23 | Ордена Трудового Красного Знамени Институт Высокомолекулярных Соединений Ан Ссср | Способ эксклюзионной жидкостной хроматографии полимеров |
| FR2598917B1 (fr) * | 1986-05-21 | 1988-08-19 | Pasteur Institut | Nouvelle lymphokine suppressive de l'activation plaquettaire, son procede d'isolement et de purification et medicaments la contenant |
| JPH0789951B2 (ja) * | 1986-06-18 | 1995-10-04 | 財団法人阪大微生物病研究会 | 遺伝子発現産物の精製法 |
| JPS63225373A (ja) * | 1986-07-24 | 1988-09-20 | Sumitomo Pharmaceut Co Ltd | 新規チアゾリジン−4−オン誘導体およびその酸付加塩 |
| US4725673A (en) * | 1986-08-29 | 1988-02-16 | Alpha Therapeutic Corporation | Plasma fraction purification using silica resin bound to a ligand |
| US4777242A (en) * | 1986-10-10 | 1988-10-11 | Phillips Petroleum Company | Purification of recombinant tumor necrosis factor |
| DE3639949A1 (de) * | 1986-11-22 | 1988-06-09 | Diagen Inst Molekularbio | Verfahren zur trennung von langkettigen nukleinsaeuren |
| US4732683A (en) * | 1986-12-02 | 1988-03-22 | Biospectrum, Inc. | Purification method for alpha interferon |
| US4894330A (en) * | 1986-12-23 | 1990-01-16 | Cetus Corporation | Purification of recombinant beta-interferon incorporating RP-HPLC |
| US4908432A (en) * | 1987-01-09 | 1990-03-13 | New York University | Novel polypeptide having gamma-interferon activity |
| US5084384A (en) * | 1987-04-23 | 1992-01-28 | Monsanto Company | Secretion of insulin-like growth factor-I |
| JPS6419024A (en) * | 1987-07-15 | 1989-01-23 | Tosoh Corp | Separation of immunoglobulin g subclass |
| JPS6451097A (en) * | 1987-08-21 | 1989-02-27 | Toray Industries | Purification of fused protein |
| US5004688A (en) * | 1988-04-15 | 1991-04-02 | Phillips Petroleum Company | Purification of hepatitis proteins |
| DD286721A7 (de) * | 1988-05-30 | 1991-02-07 | Adw Ddr | Verfahren zur gewinnung von protein a |
| DD298275A5 (de) * | 1988-05-30 | 1992-02-13 | Zentralinstitut Fuer Mikrobiologie U. Experiment. Therapie D. Adw D. Ddr (Zimet),De | Verfahren zur reindarstellung von protein a |
| KR900000748A (ko) * | 1988-06-17 | 1990-01-31 | 안시환 | 무인반송차의 교통 통제용 센서 유니트 |
| JP2517100B2 (ja) * | 1989-03-08 | 1996-07-24 | 協和醗酵工業株式会社 | ヒト顆粒球コロニ―刺激因子活性を有する蛋白質の精製法 |
| US5158875A (en) * | 1989-08-25 | 1992-10-27 | Amgen Inc. | Production of biologically active insulin-like growth factor i from high expression host cell systems |
| FR2653034A1 (fr) * | 1989-10-13 | 1991-04-19 | Centre Nat Rech Scient | Procede de preparation d'un produit particulaire poreux regiospecifique, produits obtenus et application notamment aux separations chromatographiques. |
| DE69013471T2 (de) * | 1989-12-05 | 1995-03-30 | Merck & Co Inc | Methode zur Stabilisierung von rekombinanten Hepatitis-B-Virus-Oberflächenproteinen aus Hefe. |
| JPH04130131A (ja) * | 1990-09-20 | 1992-05-01 | Polyplastics Co | 加工が容易な全芳香族ポリエステル |
| KR920008377A (ko) * | 1990-10-16 | 1992-05-27 | 까롤 미셀 벵그리예프 | 차량현가용 진동방지절연부재의 제조방법 |
| DE4042745B4 (de) * | 1990-10-24 | 2009-12-03 | Skf Gmbh | Federnd einstellbare Spannvorrichtung |
| US5231178A (en) * | 1991-01-16 | 1993-07-27 | The Salk Institute Biotechnology/Industrial Associates, Inc. | Method for the purification of intact, correctly-folded insulin-like growth factor-1 |
| US5449750A (en) * | 1991-06-20 | 1995-09-12 | Snow Brand Milk Products Co., Ltd. | Prolyl endopeptidase inhibitors SNA-115 and SNA-115T, and process for the production and productive strain thereof |
| US5278284A (en) * | 1992-05-14 | 1994-01-11 | Miller Brewing Company | Protein purification method |
-
1993
- 1993-12-13 US US08/166,337 patent/US5451660A/en not_active Expired - Lifetime
-
1994
- 1994-12-06 EP EP95903202A patent/EP0734393B1/en not_active Expired - Lifetime
- 1994-12-06 DE DE69417765T patent/DE69417765T2/de not_active Expired - Lifetime
- 1994-12-06 CA CA002177575A patent/CA2177575C/en not_active Expired - Fee Related
- 1994-12-06 AT AT95903202T patent/ATE178612T1/de active
- 1994-12-06 JP JP51681795A patent/JP3843373B2/ja not_active Expired - Fee Related
- 1994-12-06 WO PCT/US1994/013983 patent/WO1995016701A1/en not_active Ceased
- 1994-12-06 DK DK95903202T patent/DK0734393T3/da active
- 1994-12-06 ES ES95903202T patent/ES2131797T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO1995016701A1 (en) | 1995-06-22 |
| CA2177575C (en) | 2008-04-22 |
| ES2131797T3 (es) | 1999-08-01 |
| DE69417765T2 (de) | 1999-09-02 |
| ATE178612T1 (de) | 1999-04-15 |
| EP0734393B1 (en) | 1999-04-07 |
| JPH09506617A (ja) | 1997-06-30 |
| DE69417765D1 (de) | 1999-05-12 |
| US5451660A (en) | 1995-09-19 |
| CA2177575A1 (en) | 1995-06-22 |
| EP0734393A1 (en) | 1996-10-02 |
| JP3843373B2 (ja) | 2006-11-08 |
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