ES2058921T3 - Sintesis de polimeros inmovilizados a escala muy grande. - Google Patents

Sintesis de polimeros inmovilizados a escala muy grande.

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Publication number
ES2058921T3
ES2058921T3 ES90909187T ES90909187T ES2058921T3 ES 2058921 T3 ES2058921 T3 ES 2058921T3 ES 90909187 T ES90909187 T ES 90909187T ES 90909187 T ES90909187 T ES 90909187T ES 2058921 T3 ES2058921 T3 ES 2058921T3
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ES
Spain
Prior art keywords
substrate
synthesis
large scale
immobilized polymers
irradiated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90909187T
Other languages
English (en)
Inventor
Michael C Pirrung
J Leighton Read
Stephen P A Fodor
Lubert Stryer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Affymax Technologies NV
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Affymax Technologies NV
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Application filed by Affymax Technologies NV filed Critical Affymax Technologies NV
Application granted granted Critical
Publication of ES2058921T3 publication Critical patent/ES2058921T3/es
Anticipated expiration legal-status Critical
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    • C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
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    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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Abstract

SE DESCRIBE UN METODO Y DISPOSITIVO PARA LA PREPARACION DE SECUENCIAS SOBRE UN SUSTRATO EN POSICIONES CONOCIDAS. LAS POSICIONES CONOCIDAS (10) DE UN SUSTRATO (2) SON IRRADIADAS POR MEDIO DE UNA MASCARA (8) DE MANERA QUE ACTIVEN UN MATERIAL PARA SU ENLACE (4). EL SUSTRATO ES EXPUESTO A CONTINUACION A UN PRIMER MATERIAL (12) PARA SU ENLACE CON LO ANTERIOR. SEGUNDAS POSICIONES (14) SON IRRADIADAS A CONTINUACION A TRAVES DE LA MASCARA Y EXPUESTA A UN SEGUNDO MATERIAL (16). SE PUEDEN FORMAR UNA VARIEDAD DE SECUENCIAS A TRAVES DE LA IRRADIACION SELECTIVA DEL SUSTRATO SEGUIDO DE LA APLICACION DE MATERIALES SELECCIONADOS. TAMBIEN SE DESCRIBE UN SISTEMA REACTOR Y UN SISTEMA DE DETECCION DE FLUORESCENCIA.
ES90909187T 1989-06-07 1990-06-07 Sintesis de polimeros inmovilizados a escala muy grande. Expired - Lifetime ES2058921T3 (es)

Applications Claiming Priority (2)

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US36290189A 1989-06-07 1989-06-07
US07/492,462 US5143854A (en) 1989-06-07 1990-03-07 Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof

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ES2058921T3 true ES2058921T3 (es) 1994-11-01

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ES94200059T Expired - Lifetime ES2129101T3 (es) 1989-06-07 1990-06-07 Metodo y aparato para investigar secuencias de polinucleotidos o de aminoacidos.
ES90909187T Expired - Lifetime ES2058921T3 (es) 1989-06-07 1990-06-07 Sintesis de polimeros inmovilizados a escala muy grande.

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ES94200059T Expired - Lifetime ES2129101T3 (es) 1989-06-07 1990-06-07 Metodo y aparato para investigar secuencias de polinucleotidos o de aminoacidos.

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