FR2113733A5 - - Google Patents

Info

Publication number
FR2113733A5
FR2113733A5 FR7140259A FR7140259A FR2113733A5 FR 2113733 A5 FR2113733 A5 FR 2113733A5 FR 7140259 A FR7140259 A FR 7140259A FR 7140259 A FR7140259 A FR 7140259A FR 2113733 A5 FR2113733 A5 FR 2113733A5
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7140259A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Organon NV
Original Assignee
Organon NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Organon NV filed Critical Organon NV
Application granted granted Critical
Publication of FR2113733A5 publication Critical patent/FR2113733A5/fr
Expired legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/964—Chemistry: molecular biology and microbiology including enzyme-ligand conjugate production, e.g. reducing rate of nonproductive linkage
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/808—Automated or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y10S436/817—Steroids or hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
FR7140259A 1970-11-10 1971-11-10 Expired FR2113733A5 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL707016396A NL154598B (nl) 1970-11-10 1970-11-10 Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.

Publications (1)

Publication Number Publication Date
FR2113733A5 true FR2113733A5 (fr) 1972-06-23

Family

ID=19811504

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7140259A Expired FR2113733A5 (fr) 1970-11-10 1971-11-10

Country Status (16)

Country Link
US (1) US3850752A (fr)
AU (1) AU468060B2 (fr)
BE (1) BE775187A (fr)
BR (1) BR7107459D0 (fr)
CA (1) CA967464A (fr)
CH (1) CH617774A5 (fr)
DE (1) DE2155658C3 (fr)
DK (1) DK140268B (fr)
ES (1) ES396741A1 (fr)
FI (1) FI54033C (fr)
FR (1) FR2113733A5 (fr)
GB (1) GB1348935A (fr)
IT (1) IT986829B (fr)
NL (1) NL154598B (fr)
SE (1) SE451162B (fr)
ZA (1) ZA717192B (fr)

Families Citing this family (1724)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6630328B2 (en) 1909-07-15 2003-10-07 Genencor International, Inc. Increasing production of proteins in gram-positive microorganisms
USRE31006E (en) * 1968-09-24 1982-08-03 Akzona Incorporated Process for the demonstration and determination of reaction components having specific binding affinity for each other
US4191613A (en) * 1971-05-14 1980-03-04 Syva Company Malate dehydrogenase conjugates for enzyme immunoassays
US4282325A (en) * 1971-05-14 1981-08-04 Syva Company Enzyme bound corticosteroids
US3905871A (en) * 1971-05-14 1975-09-16 Syva Co Lactam conjugates to enzymes
US4203802A (en) * 1971-05-14 1980-05-20 Syva Company Inhibitable enzyme amplification assay
US4046636A (en) * 1974-06-20 1977-09-06 Syva Company Diazepam enzyme conjugates
US4039385A (en) * 1972-05-08 1977-08-02 Syva Company Cardiac glycoside enzyme conjugates
NL171930C (nl) * 1972-05-11 1983-06-01 Akzo Nv Werkwijze voor het aantonen en bepalen van haptenen, alsmede testverpakkingen.
US3790447A (en) * 1972-07-05 1974-02-05 Abbott Lab Streptococci diagnostic method
US3975237A (en) * 1972-11-06 1976-08-17 Syva Company Compounds for enzyme amplification assay - - ecgonine analogs
US3966556A (en) * 1972-11-06 1976-06-29 Syva Company Compounds for enzyme amplification assay methadone analogs
US4040907A (en) * 1974-06-20 1977-08-09 Syva Company Iodothyronine enzyme conjugates
US4061466A (en) * 1974-10-16 1977-12-06 Ingvar Gosta Holger Sjoholm Biologically active composition and the use thereof
NL7501215A (nl) * 1975-02-01 1976-08-03 Akzo Nv Methode voor het aantonen en bepalen van een antigeen of antilichaam.
US4043872A (en) * 1975-02-20 1977-08-23 Syva Company Polyiodothyronine immunoassay
USRE32696E (en) * 1975-09-04 1988-06-14 Akzona Incorporated Enzymatic immunological method for determination of antigens and antibodies
US4096138A (en) * 1975-12-08 1978-06-20 Scherr George H Immunological test procedure
US4166767A (en) * 1976-03-25 1979-09-04 Dainippon Pharmaceutical Co., Ltd. Insolubilized antibody
JPS5341420A (en) * 1976-09-29 1978-04-14 Mochida Pharm Co Ltd Immunochemically measuring methoa of hapten
GB1572220A (en) * 1976-10-07 1980-07-30 Mochida Pharm Co Ltd Immunochemical process of measuring physiologically active substances
US4098876A (en) * 1976-10-26 1978-07-04 Corning Glass Works Reverse sandwich immunoassay
US4134792A (en) * 1976-12-06 1979-01-16 Miles Laboratories, Inc. Specific binding assay with an enzyme modulator as a labeling substance
IT1153999B (it) * 1977-03-15 1987-01-21 Snam Progetti Composizione atta alla determinazione della triiodotironina e metodo diagnostico impiegante la stessa
IL51667A (en) * 1977-03-16 1979-10-31 Miles Yeda Ltd Immunoassay for the determination of a hapten
US4156081A (en) * 1977-04-15 1979-05-22 Syva Company Theophylline antigens and antibodies
IT1114861B (it) * 1977-05-12 1986-01-27 Sclavo Inst Sieroterapeut Metodo per la determinazione del contenuto di costituenti di fluidi biologici e mezzi adatti allo scopo
FR2422956A1 (fr) * 1978-04-13 1979-11-09 Pasteur Institut Procede de detection et de caracterisation d'un acide nucleique ou d'une sequence de celui-ci, et reactif enzymatique pour la mise en oeuvre de ce procede
US5605800A (en) * 1978-04-13 1997-02-25 Institut Pasteur Method of detecting and characterizing a nucleic acid or a sequence of the latter, and enzymatic reactant for the application of this method
DE2825650C3 (de) * 1978-06-12 1981-02-05 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur Bestimmung des Thyroxin-bindungsindex im Serum
US4269938A (en) * 1979-03-08 1981-05-26 Eastman Kodak Company Assay of peroxidatively active materials
US4376825A (en) * 1979-05-07 1983-03-15 Syva Company Enzyme amplification compounds for assays for androgens
JPS55152459A (en) * 1979-05-18 1980-11-27 Yamasa Shoyu Co Ltd Method and reagent for measuring quantity of cyclic nucleotide
US4289748A (en) * 1979-05-31 1981-09-15 United States Of America Ultrasensitive enzymatic radioimmunoassay method
US4391904A (en) * 1979-12-26 1983-07-05 Syva Company Test strip kits in immunoassays and compositions therein
US4299916A (en) * 1979-12-26 1981-11-10 Syva Company Preferential signal production on a surface in immunoassays
FI61965C (fi) 1980-01-17 1982-10-11 Suovaniemi Finnpipette Foerfarande foer detektering av hemoglobin i avfoering
US4347312A (en) * 1980-03-20 1982-08-31 Research Triangle Institute Detection of antibiotics in milk
JPS5714748A (en) * 1980-07-01 1982-01-26 Dainippon Pharmaceut Co Ltd Kit for quantitative determination of valproic acid and its method for quantitative determination
US4323647A (en) * 1980-10-15 1982-04-06 University Of Miami Steric hindrance enzyme immunoassay
US4604365A (en) * 1981-06-02 1986-08-05 Electro-Nucleonics, Inc. Immunoprecipitation assay
JPS58500874A (ja) * 1981-06-02 1983-05-26 エレクトロ−ヌ−　クレオニツクス、インコ−ポレ−テツド 免疫沈殿分析
US5703206A (en) * 1981-09-08 1997-12-30 Univ Rockefeller Macrophage inflammatory protein 2 (MIP-2)
US4419453A (en) * 1981-09-28 1983-12-06 The Dow Chemical Company Immunological agglutination assays with dyed or colored latex and kits
US4506009A (en) * 1982-03-30 1985-03-19 University Of California Heterogeneous immunoassay method
US4535057A (en) * 1982-07-26 1985-08-13 Amf Incorporated Immunoassay employing monoclonal herpes simplex antibody and biotin-avidin detection system
US4530900A (en) * 1982-09-13 1985-07-23 Seragen Diagnostics Inc. Soluble insoluble polymers in enzymeimmunoassay
ZA841924B (en) * 1983-07-25 1984-10-31 Becton Dickinson Co Chromogenic tracers for use in an assay
EP0154631A4 (fr) * 1983-07-27 1985-11-25 American Hospital Supply Corp Procede de reduction selective de nitrile.
FR2550799B1 (fr) * 1983-08-17 1986-02-21 Commissariat Energie Atomique Compose marque par une enzyme, son procede de preparation et son utilisation en enzymoimmunologie
DE3433652A1 (de) * 1984-09-13 1986-03-20 Boehringer Mannheim Gmbh, 6800 Mannheim Immunchemisches messverfahren fuer haptene und proteine
US4713347A (en) * 1985-01-14 1987-12-15 Sensor Diagnostics, Inc. Measurement of ligand/anti-ligand interactions using bulk conductance
US4786594A (en) * 1986-05-14 1988-11-22 Syntex (U.S.A.) Inc. Enzyme immunoassay
DE68928124T2 (de) * 1988-09-02 1997-10-16 Chiron Corp., Emeryville, Calif. Makrophagenabgeleiteter entzündungsmediator(mip-2)
EP0703296B1 (fr) 1988-09-29 1998-07-22 Chiron Corporation Détermination de polynucléotides par substitution d'un brin sur une sonde de capture
CA2029006C (fr) * 1990-07-27 2001-07-17 Michael R. Detty Produits d'oxydation d'un acide dicarboxylique
CA2031109C (fr) * 1990-07-27 1992-01-28 Susan J. Danielson Analogues de ligand pour des immunodosages derives de produits d'oxydation d'un acide dicarboxylique
US5614504A (en) * 1990-08-01 1997-03-25 The University Of South Florida Method of making inosine monophosphate derivatives and immunopotentiating uses thereof
US5268298A (en) * 1991-04-26 1993-12-07 Life Technologies, Inc. System for delivering oxygen to a cell culture medium
US5965379A (en) * 1991-07-19 1999-10-12 Cytimmune Sciences Inc. Method for measuring endogenous cytokines
JP3183666B2 (ja) * 1991-07-19 2001-07-09 アツセイ・リサーチ・インコーポレーテツド 内因性サイトカイン類の測定方法およびキット
US5464749A (en) 1991-07-22 1995-11-07 Bayer Corporation Immunoassay of free substances in biological fluids
US5939524A (en) * 1991-12-09 1999-08-17 The Scripps Research Institute Platelet GPIII P1A1 and P1A2 epitopes, their preparation and use
US5624804A (en) * 1991-12-20 1997-04-29 The Rockefeller University Immunochemical detection of In vivo advanced glycosylation end products
US5354692A (en) * 1992-09-08 1994-10-11 Pacific Biotech, Inc. Analyte detection device including a hydrophobic barrier for improved fluid flow
US5874423A (en) * 1992-09-10 1999-02-23 Yissum Research Development Co. Of The Hebrew University Of Jerusalem Digitalis-like compounds
US7060283B1 (en) 1992-09-15 2006-06-13 Ortho Diagnostic Systems, Inc. Immunoreactive peptides from Epstein-Barr virus
US7326535B2 (en) 1993-09-15 2008-02-05 Ortho Diagnostic Systems Inc. Immunoreactive peptides from Epstein-Barr virus
US5637467A (en) * 1992-10-13 1997-06-10 Behringwerke Ag Heterogeneous assay using a pendulous drop
US5869445A (en) * 1993-03-17 1999-02-09 University Of Washington Methods for eliciting or enhancing reactivity to HER-2/neu protein
US5801005A (en) * 1993-03-17 1998-09-01 University Of Washington Immune reactivity to HER-2/neu protein for diagnosis of malignancies in which the HER-2/neu oncogene is associated
US6953573B1 (en) * 1993-03-17 2005-10-11 University Of Washington Compounds for eliciting or enhancing immune reactivity to HER-2/neu protein for prevention or treatment of malignancies in which the HER-2/neu oncogene is associated
US6562333B1 (en) 1993-06-14 2003-05-13 Schering Corporation Purified mammalian CTLA-8 antigens and related reagents
US6495343B1 (en) 1993-06-18 2002-12-17 The Salk Institute For Biological Studies Cloning and recombinant production of CRF receptor(s)
US6638905B2 (en) 1993-06-18 2003-10-28 The Salk Institute For Biological Studies Cloning and recombinant production of CFR receptor(s)
US6103237A (en) * 1993-07-22 2000-08-15 Hybritech Incorporated Stable variant hK2 polypeptide
US5516639A (en) * 1993-07-22 1996-05-14 Mayo Foundation For Medical Education And Research Antibodies specific for human prostate glandular kallkrein
US20040259113A1 (en) * 1993-07-22 2004-12-23 Mayo Foundation For Medical Education And Research, Hybritech Incorporated Method for detection of metastatic prostate cancer
US5684144A (en) * 1993-07-28 1997-11-04 University Of North Texas Escherichia coli csrA gene, protein encoded thereby, and methods of use thereof
US6884590B1 (en) 1994-02-11 2005-04-26 Cedars-Sinai Medical Center Methods of screening for ulcerative colitis and crohn's disease
US5681699A (en) * 1994-02-11 1997-10-28 Cedars-Sinai Medical Center Methods of diagnosing ulcerative colitis and Crohn's disease
US6335160B1 (en) 1995-02-17 2002-01-01 Maxygen, Inc. Methods and compositions for polypeptide engineering
US6406855B1 (en) 1994-02-17 2002-06-18 Maxygen, Inc. Methods and compositions for polypeptide engineering
AU699748B2 (en) * 1994-05-10 1998-12-10 Hybritech Incorporated Recombinant HK2 polypeptide
AU2635295A (en) * 1994-06-13 1996-01-05 Henry Ford Health System A novel neuronal-neonatal gene: neuronatin
US5589344A (en) * 1994-06-15 1996-12-31 Johnson & Johnson Clinical Diagnostics, Inc. Test kit and method for competitive specific binding assay
DE69521002T3 (de) 1994-08-12 2010-02-25 The University Of Utah Research Foundation, Salt Lake City Mutationen des mit 17q verbundenen Ovarial- und Brustkrebs Empfindlichkeitsgens
EP0699754B2 (fr) 1994-08-12 2009-08-12 The University of Utah Research Foundation Méthode de diagnose pour la prédisposition au cancer du sein et des ovaires
US6001968A (en) 1994-08-17 1999-12-14 The Rockefeller University OB polypeptides, modified forms and compositions
US6471956B1 (en) 1994-08-17 2002-10-29 The Rockefeller University Ob polypeptides, modified forms and compositions thereto
US6309853B1 (en) 1994-08-17 2001-10-30 The Rockfeller University Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof
US6124439A (en) * 1994-08-17 2000-09-26 The Rockefeller University OB polypeptide antibodies and method of making
US6048837A (en) * 1994-08-17 2000-04-11 The Rockefeller University OB polypeptides as modulators of body weight
US6350730B1 (en) 1994-08-17 2002-02-26 The Rockefeller University OB polypeptides and modified forms as modulators of body weight
US6124448A (en) * 1994-08-17 2000-09-26 The Rockfeller University Nucleic acid primers and probes for the mammalian OB gene
US8236493B2 (en) 1994-10-21 2012-08-07 Affymetrix, Inc. Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA
US6974666B1 (en) * 1994-10-21 2005-12-13 Appymetric, Inc. Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA
US6531277B2 (en) 1994-10-25 2003-03-11 The Curators Of The University Of Missouri Endometriosis-specific secretory protein
US5843673A (en) * 1994-10-25 1998-12-01 Curators Of The University Of Missouri Method of screening for endometriosis
US20030152909A1 (en) * 1994-11-16 2003-08-14 Mitrani Eduardo N. In vitro micro-organs, and uses related thereto
US5633149A (en) * 1994-12-07 1997-05-27 Incyte Pharmaceuticals, Inc. Polynucleotide encoding novel chemokine expressed in inflamed adenoid
US7005509B1 (en) 1995-02-17 2006-02-28 Incyte Corporation Chemokine PANEC-1 polynucleotides and compositions and methods related thereto
US6506553B1 (en) 1995-03-30 2003-01-14 Ortho Diagnostics Systems, Inc. Method for diagnosis of Epstein-Barr virus associated disease
US5858661A (en) 1995-05-16 1999-01-12 Ramot-University Authority For Applied Research And Industrial Development Ataxia-telangiectasia gene and its genomic organization
US5777093A (en) * 1995-05-16 1998-07-07 Ramot-University Authority For Applied Research & Industrial Development Ltd. cDNAs associated with ataxia-telangiectasia
US5728807A (en) * 1995-05-16 1998-03-17 Ramot-University Authority For Applied Research And Industrial Development, Ltd. Mutated proteins associated with ataxia-telangiectasia
GB0112226D0 (en) * 2001-05-18 2001-07-11 Danisco Method of improving dough and bread quality
WO1997000271A1 (fr) 1995-06-14 1997-01-03 The Regents Of The University Of California Nouveaux anticorps humains a forte affinite diriges contre des antigenes tumoraux
US5837492A (en) 1995-12-18 1998-11-17 Myriad Genetics, Inc. Chromosome 13-linked breast cancer susceptibility gene
CA2239733C (fr) 1995-12-18 2001-04-03 Myriad Genetics, Inc. Gene de predisposition au cancer du sein lie au chromosome 13
US20010018514A1 (en) * 1998-07-31 2001-08-30 Mcgall Glenn H. Nucleic acid labeling compounds
US20040210045A1 (en) * 1996-01-23 2004-10-21 Mcgall Glenn Nucleic acid labeling compounds
US7282327B2 (en) * 1996-01-23 2007-10-16 Affymetrix, Inc. Nucleic acid labeling compounds
US7291463B2 (en) 1996-01-23 2007-11-06 Affymetrix, Inc. Nucleic acid labeling compounds
US6965020B2 (en) 1996-01-23 2005-11-15 Affymetrix, Inc. Nucleic acid labeling compounds
EP0880598A4 (fr) 1996-01-23 2005-02-23 Affymetrix Inc Evaluation rapide de difference d'abondance d'acides nucleiques, avec un systeme d'oligonucleotides haute densite
US7423143B2 (en) * 1996-01-23 2008-09-09 Affymetrix. Inc. Nucleic acid labeling compounds
US6864059B2 (en) * 1996-01-23 2005-03-08 Affymetrix, Inc. Biotin containing C-glycoside nucleic acid labeling compounds
WO1997029212A1 (fr) 1996-02-08 1997-08-14 Affymetrix, Inc. Speciation de micro-organismes a partir de microplaquettes et caracterisation des phenotypes de ceux-ci
US6924094B1 (en) 1996-02-08 2005-08-02 Affymetrix, Inc. Chip-based species identification and phenotypic characterization of microorganisms
EP1728875A3 (fr) 1996-02-08 2007-05-09 Affymetrix, Inc. Spéciation de micro-organismes à partir de micro plaquettes et caractérisation des phénotypes de ceux-ci
JP2000507245A (ja) * 1996-03-22 2000-06-13 ユニバーシティー オブ ジョージア リサーチ ファウンデーション，インコーポレイテッド Ｐｏｒｐｈｙｒｏｍｏｎａｓ ｇｉｎｇｉｖａｌｉｓペプチドを含む免疫原性組成物および方法
US5882644A (en) * 1996-03-22 1999-03-16 Protein Design Labs, Inc. Monoclonal antibodies specific for the platelet derived growth factor β receptor and methods of use thereof
US6942862B2 (en) * 1996-04-01 2005-09-13 University Of Washington Methods and compositions to generate immunity in humans against self tumor antigens by immunization with homologous foreign proteins
BR9710811A (pt) * 1996-05-22 1999-08-17 Novopharm Biotech Inc Fragmentos de liga-Æo de antigeno que detecta especificamente c-lulas cancerigenas nucleotideos que codificam os fragmentos e o seu uso para a profilaxia e detec-Æo de c-nceres
US20050214827A1 (en) * 1996-07-08 2005-09-29 Burstein Technologies, Inc. Assay device and method
IL127938A (en) 1996-07-08 2002-09-12 Burstein Lab Inc A device with a main signal fixed for diagnostic applications and a test method
US6342349B1 (en) 1996-07-08 2002-01-29 Burstein Technologies, Inc. Optical disk-based assay devices and methods
US6331275B1 (en) 1996-07-08 2001-12-18 Burstein Technologies, Inc. Spatially addressable, cleavable reflective signal elements, assay device and method
US20050069923A1 (en) * 1996-07-08 2005-03-31 Mullis Kary Banks Dual bead assays using cleavable spacers and/or ligation to improve specificity and sensitivity including related methods and apparatus
DK0920505T3 (da) 1996-08-16 2008-09-08 Schering Corp Pattedyrcelleoverfladeantigener og tilhörende reagenser
US20070299005A1 (en) * 1996-09-24 2007-12-27 Tanox, Inc. Family of genes encoding apoptosis-related peptides, peptides encoded thereby and methods of use thereof
ATE318915T1 (de) 1996-09-24 2006-03-15 Tanox Inc Genfamilie von apoptose-verwandten peptiden, dadurch kodierte peptide und verfahren zu deren herstellung
US6093809A (en) * 1996-10-01 2000-07-25 University Technology Corporation Telomerase
US6808880B2 (en) * 1996-10-01 2004-10-26 Geron Corporation Method for detecting polynucleotides encoding telomerase
EA199900355A1 (ru) 1996-10-01 2000-08-28 Джерон Корпорейшн Теломераза обратная тринскриптаза
US6475789B1 (en) 1996-10-01 2002-11-05 University Technology Corporation Human telomerase catalytic subunit: diagnostic and therapeutic methods
US6610839B1 (en) * 1997-08-14 2003-08-26 Geron Corporation Promoter for telomerase reverse transcriptase
US7585622B1 (en) 1996-10-01 2009-09-08 Geron Corporation Increasing the proliferative capacity of cells using telomerase reverse transcriptase
US6261836B1 (en) 1996-10-01 2001-07-17 Geron Corporation Telomerase
GB9907461D0 (en) 1999-03-31 1999-05-26 King S College London Neurite regeneration
US6479263B1 (en) 1996-11-14 2002-11-12 Baylor College Of Medicine Method for detection of micrometastatic prostate cancer
US5976803A (en) 1996-11-15 1999-11-02 The Board Of Regents Of The University Of Texas System Genetic test for equine severe combined immunodeficiency disease
PT1114864E (pt) 1996-12-13 2008-10-08 Schering Corp Antigénios de superfície de células de mamífero, reagentes relacionados
US5840322A (en) * 1996-12-19 1998-11-24 Ramot-University Authority For Applied Research & Industrial Devel. Ltd. Anti-oral-microbial adhesion fraction derived from vaccinium
EP2172478A3 (fr) 1997-02-07 2010-07-28 THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES Facteur III neurotrophe dépendant de l'activité (ADNF III)
US6268165B1 (en) 1997-03-19 2001-07-31 The Board Of Trustees Of The University Of Arkansas Methods for the early diagnosis of ovarian cancer
WO1998043484A1 (fr) 1997-04-01 1998-10-08 Calyx Therapeutics, Inc. Fraction du momordica charantia active par voie orale, ses peptides actifs, et leur utilisation dans le traitement du diabete
US20050013825A1 (en) * 1997-04-18 2005-01-20 Geron Corporation Vaccine containing the catalytic subunit of telomerase for treating cancer
US7413864B2 (en) * 1997-04-18 2008-08-19 Geron Corporation Treating cancer using a telomerase vaccine
US7622549B2 (en) * 1997-04-18 2009-11-24 Geron Corporation Human telomerase reverse transcriptase polypeptides
WO2001090151A2 (fr) 2000-05-25 2001-11-29 Schering Corporation Proteines receptrices humaines, reactifs et methodes associes
EP1988166A1 (fr) 1997-05-07 2008-11-05 Schering Corporation Protéines humaines réceptrices de type Toll, réactifs associés et procédés
US7115722B1 (en) 1997-05-22 2006-10-03 Viventia Biotech, Inc. Antigen binding fragments that specifically detect cancer cells, nucleotides encoding the fragments, and use thereof for the prophylaxis and detection of cancers
US6528271B1 (en) * 1997-06-05 2003-03-04 Duke University Inhibition of βarrestin mediated effects prolongs and potentiates opioid receptor-mediated analgesia
US5891646A (en) * 1997-06-05 1999-04-06 Duke University Methods of assaying receptor activity and constructs useful in such methods
US7541151B2 (en) 1997-06-05 2009-06-02 Duke University Single-cell biosensor for the measurement of GPCR ligands in a test sample
AU8259798A (en) 1997-06-20 1999-01-04 George G Klee Method for detection of breast cancer
US20020122807A1 (en) * 1998-07-07 2002-09-05 Dan Michael D. Antigen binding fragments, designated 4B5, that specifically detect cancer cells, nucleotides encoding the fragments, and use thereof for the prophylaxis and detection of cancers
AR014891A1 (es) 1997-07-09 2001-04-11 Schering Corp Genes aislados de proteinas de membranas de mamiferos; reactivos relacionados
US6228638B1 (en) 1997-07-11 2001-05-08 University Of North Texas, Health Science Center At Fort Worth Escherichia coli CSRB gene and RNA encoded thereby
US6506579B1 (en) 1997-07-15 2003-01-14 Genencor International, Inc. Increasing production of proteins in gram-positive microorganisms using SecG
US20030157642A1 (en) 1997-07-15 2003-08-21 Caldwell Robert M. Increasing production of proteins in gram-positive microorganisms
US6762039B2 (en) * 1997-07-15 2004-07-13 Genencor International, Inc. Bacillus subtillis with an inactivated cysteine protease-1
US6723550B1 (en) * 1997-07-15 2004-04-20 Genencor International, Inc. Proteases from gram-positive organisms
US6521421B1 (en) 1997-07-16 2003-02-18 Genencor International, Inc. Expression vectors encoding Bacillus subtilis disulfide bond isomerase and methods of secreting proteins in gram-positive microorganisms using the same
ZA986596B (en) 1997-07-25 1999-02-08 Schering Corp Mammalian cytokine related reagents
US6180411B1 (en) 1997-08-01 2001-01-30 The Regents Of The University Of California Light-triggered indicators that memorize analyte concentrations
EP1798286B1 (fr) 1997-08-01 2011-09-07 Schering Corporation Protéines de membrane cellulaire mammalienne et réactifs associes
US7252950B1 (en) * 1997-09-04 2007-08-07 The Regents Of The University Of California Assays for detecting modulators of cytoskeletal function
US6300117B1 (en) * 1997-09-15 2001-10-09 Genencor International, Inc. Proteases from gram-positive organisms
US6521440B1 (en) * 1997-09-15 2003-02-18 Genencor International, Inc. Proteases from gram-positive organisms
US7378244B2 (en) * 1997-10-01 2008-05-27 Geron Corporation Telomerase promoters sequences for screening telomerase modulators
US6284496B1 (en) 1997-10-03 2001-09-04 University Of South Florida DNA vector for determining the presence of out-of-reading-frame mutations
WO1999020788A1 (fr) 1997-10-17 1999-04-29 University Of South Florida Procede de diagnostic et de surveillance des deficiences immunitaires cellulaires
US6316241B1 (en) * 1997-11-20 2001-11-13 Genencor International, Inc. Alpha/beta hydrolase-fold enzymes
GB9724627D0 (en) 1997-11-20 1998-01-21 Genencor Int Bv Gram positive microorganism formate pathway
GB9724629D0 (en) * 1997-11-20 1998-01-21 Genencor Int Bv Alpha/beta hydrolase-fold enzymes
US6599731B1 (en) * 1997-12-30 2003-07-29 Genencor International, Inc. Proteases from gram positive organisms
US6528255B1 (en) * 1997-12-30 2003-03-04 Genencor International, Inc. Proteases from gram positive organisms
GB9727470D0 (en) * 1997-12-30 1998-02-25 Genencor Int Bv Proteases from gram positive organisms
US6465186B1 (en) * 1997-12-30 2002-10-15 Genecor International, Inc. Proteases from gram positive organisms
US7687057B2 (en) 1998-01-09 2010-03-30 Yissum Research Development Company Of The Hebrew University Of Jerusalem In vitro micro-organs, and uses related thereto
US6780609B1 (en) 1998-10-23 2004-08-24 Genome Therapeutics Corporation High bone mass gene of 1.1q13.3
US6759243B2 (en) 1998-01-20 2004-07-06 Board Of Trustees Of The University Of Illinois High affinity TCR proteins and methods
US6673914B1 (en) 1998-01-22 2004-01-06 John Wayne Cancer Institute Human tumor-associated gene
US6596501B2 (en) 1998-02-23 2003-07-22 Fred Hutchinson Cancer Research Center Method of diagnosing autoimmune disease
US6060260A (en) * 1998-02-27 2000-05-09 Dade Behring Inc. Methods for reducing adsorption in an assay
AU2980199A (en) 1998-03-04 1999-09-20 Genencor International, Inc. Modified forms of pullulanase
EP1141727A2 (fr) 1998-03-20 2001-10-10 Curators Of The University Of Missouri Compositions et methodes pour un diagnostic precoce de la grossesse
US8062908B2 (en) * 1999-03-29 2011-11-22 Orasure Technologies, Inc. Device for collection and assay of oral fluids
EP1696236B1 (fr) * 1998-03-30 2014-07-16 OraSure Technologies, Inc. Dispositif de collecte pour analyse des fluides buccaux
US6303081B1 (en) * 1998-03-30 2001-10-16 Orasure Technologies, Inc. Device for collection and assay of oral fluids
US6337200B1 (en) * 1998-03-31 2002-01-08 Geron Corporation Human telomerase catalytic subunit variants
EP1095183B1 (fr) * 1998-03-31 2012-02-22 Esoterix Genetic Laboratories, LLC Methodes de diagnostic et de traitement de cancer du poumon
US7108968B2 (en) * 1998-04-03 2006-09-19 Affymetrix, Inc. Mycobacterial rpoB sequences
AU3745799A (en) 1998-04-14 1999-11-01 Regents Of The University Of California, The Assays for the detection of microtubule depolymerization inhibitors
US6872537B1 (en) 1998-04-14 2005-03-29 Regents Of The University Of California Assays for the detection of microtubule depolymerization inhibitors
US6699969B1 (en) 1998-04-14 2004-03-02 The Regents Of The University Of California Assays for the detection of microtubule depolymerization inhibitors
US20080206206A1 (en) 1998-05-07 2008-08-28 University Of South Florida Bone marrow-derived neuronal cells
US6344443B1 (en) 1998-07-08 2002-02-05 University Of South Florida Peptide antagonists of tumor necrosis factor alpha
US7605149B1 (en) 1998-07-13 2009-10-20 University Of South Florida Modulation of the phospholipase A2 pathway as a therapeutic
EP1097378A2 (fr) * 1998-07-21 2001-05-09 Burstein Laboratories Inc. Dispositifs de dosage utilisant des disques optiques et methodes correspondantes
ATE231186T1 (de) 1998-07-21 2003-02-15 Danisco Lebensmittel
US6312689B1 (en) 1998-07-23 2001-11-06 Millennium Pharmaceuticals, Inc. Anti-CCR2 antibodies and methods of use therefor
US6187563B1 (en) 1998-08-07 2001-02-13 Yale University βIV-spectrin-polypeptides and nucleic acids encoding same
SE9803099D0 (sv) 1998-09-13 1998-09-13 Karolinska Innovations Ab Nucleic acid transfer
AU6394399A (en) * 1998-09-18 2000-04-10 Rockefeller University, The Lynx, a novel family of receptor ligands in the central nervous system, corresponding nucleic acids and proteins and uses thereof
CA2343979C (fr) 1998-09-21 2011-11-15 Schering Corporation Interleukine humaine b50, ses utilisations therapeutiques
EP0997476A3 (fr) 1998-09-25 2000-07-19 Schering-Plough Anticorps contre un antigène de cellules Langerhans mammifères et leurs utilisations
IL142094A0 (en) 1998-09-29 2002-03-10 Gamida Cell Ltd Methods of controlling proliferation and differentiation of stem and progenitor cells
KR20010089764A (ko) 1999-01-11 2001-10-08 둘락 노먼 씨. 인터류킨-17과 관련된 포유류의 사이토카인, 이를코딩하는 폴리뉴클레오티드 및 이의 용도
MXPA01007820A (es) 1999-02-04 2003-06-19 Technion Res & Dev Foundation Metodo y aparato para mantenimiento y expansion de celulas de tallo hemopoyeticas y/o celulas progenitoras.
US6156515A (en) * 1999-02-09 2000-12-05 Urocor, Inc. Prostate-specific gene for diagnosis, prognosis and management of prostate cancer
DE60041393D1 (de) 1999-03-11 2009-03-05 Schering Corp Cytokine aus säugetieren, verwandte reagenzien und verfahren
EP2336321A1 (fr) 1999-05-13 2011-06-22 Medical Research Council Recepteur homologue de OX2.
AU5011200A (en) 1999-05-14 2000-12-05 Arbor Vita Corporation Molecular interactions in hematopoietic cells
US6440682B1 (en) * 1999-05-28 2002-08-27 Detroit R&D Inc. Detection of hypertension using immunoreactive metabolic products
US6787318B1 (en) * 1999-06-01 2004-09-07 Roskamp Research Institute, Llc Assay for evaluating the therapeutic effectiveness of agents in reducing Alzheimer's disease pathology
EP1181366B2 (fr) 1999-06-01 2013-08-21 Merck Sharp & Dohme Corp. Proteines de recepteur mammaliennes, reactifs et procedes y relatifs
US7534605B2 (en) * 1999-06-08 2009-05-19 Yissum Research Development Company Of The Hebrew University Of Jerusalem CD44 polypeptides, polynucleotides encoding same, antibodies directed thereagainst and method of using same for diagnosing and treating inflammatory diseases
GB9914210D0 (en) 1999-06-17 1999-08-18 Danisco Promoter
CA2377541A1 (fr) * 1999-06-25 2001-01-04 Eduardo N. Mitrani Procede permettant d'induire une angiogenese au moyen de micro-organes
US6531130B1 (en) * 1999-07-06 2003-03-11 The Board Of Trustees Of The Leland Stanford University Treatment of demyelinating autoimmune disease with ordered peptides
ES2330406T3 (es) 1999-07-30 2009-12-10 Schering Corporation Citocinas de mamifero; reactivos relacionados.
US6875582B1 (en) 1999-08-19 2005-04-05 Omniscience Pharmaceuticals, Inc. Methods and targets of antibiotic resistance
US7101839B1 (en) 1999-08-30 2006-09-05 Yissum Research Development Company Of The Hebrew University Of Jerusalem Methods of and compositions for inhibiting the proliferation of mammalian cells
US7811981B2 (en) * 1999-08-30 2010-10-12 Yissum Research Development Company Of The Hebrew University Of Jerusalem Methods of and compositions for inhibiting the proliferation of mammalian cells
EP1905832A3 (fr) 1999-09-09 2009-09-09 Schering Corporation Interleukin-12 P40 et interleukin B30 de mammifères, anticorps, utilisation dans des compositions pharmaceutiques
EP1903107A1 (fr) 1999-09-24 2008-03-26 Cybios LLC Cellules souches pluripotentes de type embryonnaires, leurs compositions, procédés et utilisations
US6998232B1 (en) 1999-09-27 2006-02-14 Quark Biotech, Inc. Methods of diagnosing bladder cancer
US7332275B2 (en) 1999-10-13 2008-02-19 Sequenom, Inc. Methods for detecting methylated nucleotides
US7030228B1 (en) 1999-11-15 2006-04-18 Miltenyi Biotec Gmbh Antigen-binding fragments specific for dendritic cells, compositions and methods of use thereof antigens recognized thereby and cells obtained thereby
IL149698A0 (en) * 1999-11-19 2002-11-10 Yissum Res Dev Co Aspergillus niger beta-glucosidase gene, protein and uses thereof
CA2389979C (fr) 1999-11-24 2011-08-16 Schering Corporation Procedes d'inhibition de metastases
DK1247095T3 (da) 1999-12-06 2008-12-08 Univ Illinois TCR-proteiner med höj affinitet samt fremgangsmåder
US6544792B1 (en) 1999-12-21 2003-04-08 Genencor International, Inc. Production of secreted polypeptides
US6544506B2 (en) * 2000-01-05 2003-04-08 Yeda Research & Development Co. Ltd. Veto cells effective in preventing graft rejection and devoid of graft versus host potential
AU2001225441A1 (en) * 2000-01-24 2001-07-31 Agricultural Research Organization The Volcani Center Plants tolerant of environmental stress conditions, methods of generating same and novel polynucleotide sequence utilized thereby
DE10003734A1 (de) * 2000-01-28 2001-08-02 Bosch Gmbh Robert Detektionsverfahren und -vorrichtung
AU3988401A (en) * 2000-02-25 2001-09-03 Ludwig Inst Cancer Res Materials and methods involving hybrid vascular endothelial growth factor dnas and proteins
US20040002068A1 (en) 2000-03-01 2004-01-01 Corixa Corporation Compositions and methods for the detection, diagnosis and therapy of hematological malignancies
US7829313B2 (en) * 2000-03-24 2010-11-09 Eppendorf Array Technologies Identification and quantification of a plurality of biological (micro)organisms or their components
US8288128B2 (en) * 2004-11-18 2012-10-16 Eppendorf Array Technologies S.A. Real-time quantification of multiple targets on a micro-array
US7875442B2 (en) * 2000-03-24 2011-01-25 Eppendorf Array Technologies Identification and quantification of a plurality of biological (micro)organisms or their components
EP1294748B1 (fr) 2000-03-27 2010-06-30 Technion Research and Development of Foundation, Ltd. Complexes majeurs d'histocompatibilite monocatenaires de classe 1, constructions les codant et leurs methodes de production
US20040191260A1 (en) * 2003-03-26 2004-09-30 Technion Research & Development Foundation Ltd. Compositions capable of specifically binding particular human antigen presenting molecule/pathogen-derived antigen complexes and uses thereof
JP4868681B2 (ja) 2000-03-31 2012-02-01 ザ スクリプス リサーチ インスティチュート 血管新生の調節のために有用なヒトアミノアシル−ｔＲＮＡシンテターゼポリペプチド
US20030108927A1 (en) * 2000-04-03 2003-06-12 Kathryn Leishman Compositions and methods for the prevention, treatment and detection of tuberculosis and other diseases
ES2317898T3 (es) 2000-04-18 2009-05-01 Schering Corporation Usos medicinales de agonistas y antogonistas de il-174.
IL135884A (en) * 2000-04-30 2005-08-31 Yissum Res Dev Co Method for measuring non-transferrin bound iron
US7422743B2 (en) 2000-05-10 2008-09-09 Schering Corporation Mammalian receptor protein DCRS5;methods of treatment
US6756481B2 (en) 2000-05-10 2004-06-29 Schering Corporation IL-23 receptor binding compositions
WO2005000087A2 (fr) * 2003-06-03 2005-01-06 Chiron Corporation Produits genetiques exprimes de facon differentielle dans des cellules cancereuses du colon et leurs methodes d'utilisation ii
US20030031675A1 (en) 2000-06-06 2003-02-13 Mikesell Glen E. B7-related nucleic acids and polypeptides useful for immunomodulation
US6958214B2 (en) * 2000-07-10 2005-10-25 Sequenom, Inc. Polymorphic kinase anchor proteins and nucleic acids encoding the same
HUP0300810A2 (hu) 2000-07-20 2003-08-28 M.G.V.S. Ltd. Mesterséges értranszplantátum, valamint ennek létrehozása és alkalmazása
US20040037828A1 (en) 2002-07-09 2004-02-26 Bar-Ilan University Methods and pharmaceutical compositions for healing wounds
AU2001281168A1 (en) 2000-08-08 2002-02-18 St. Jude Children's Research Hospital Group b streptococcus polypeptides nucleic acids and therapeutic compositions and vaccines thereof
DE60143754D1 (de) 2000-08-08 2011-02-10 Technion Res And Dev Of Foundation Ltd Pharmazeutische zusammensetzungen und methoden nützlich zur behandlung von krebs oder leberfibrose
US20030114410A1 (en) 2000-08-08 2003-06-19 Technion Research And Development Foundation Ltd. Pharmaceutical compositions and methods useful for modulating angiogenesis and inhibiting metastasis and tumor fibrosis
GB0020498D0 (en) 2000-08-18 2000-10-11 Sterix Ltd Compound
EP1683874A3 (fr) 2000-08-29 2006-10-11 YEDA RESEARCH AND DEVELOPMENT Co. LTD. Méthode pour l'isolement de gènes codant pour des protéines à fonction spécifique et pour le criblage d'agents pharmaceutiques actifs
ATE549347T1 (de) 2000-09-08 2012-03-15 Schering Corp Gene von säugetiere, und damit verbundene reagentien, methoden
DE60142840D1 (de) 2000-09-08 2010-09-30 Univ Texas Durch phagendisplay identifizierte zielpeptide des menschen und der maus
US6673623B1 (en) 2000-09-12 2004-01-06 Novocure, Inc. Methods and compositions that control lipid production
WO2002022667A2 (fr) * 2000-09-18 2002-03-21 Genencor International, Inc. Translocation des arginines couplees dans bacillus
US7632522B2 (en) * 2000-09-28 2009-12-15 Nanocyte Inc. Use of stinging cells/capsules for the delivery of active agents to keratinous substances
IL155097A0 (en) * 2000-09-28 2003-10-31 Nanocyte Inc Methods, compositions and devices utilizing stinging cells/capsules for delivering a therapeutic or a cosmetic agent into a tissue
US20070281037A9 (en) * 2000-09-28 2007-12-06 Nanocyte Inc. Sterile preparations and compositions including stinging capsules and methods of producing and using same
US7045283B2 (en) 2000-10-18 2006-05-16 The Regents Of The University Of California Methods of high-throughput screening for internalizing antibodies
US20050136431A1 (en) * 2000-11-03 2005-06-23 Oakley Robert H. Methods of screening compositions for G protein-coupled receptor desensitization inhibitory activity
US7018812B2 (en) * 2000-11-03 2006-03-28 Duke University Modified G-protein coupled receptors
US7163800B2 (en) * 2000-11-03 2007-01-16 Molecular Devices Corporation Methods of screening compositions for G protein-coupled receptor desensitization inhibitory activity
US6890734B2 (en) 2000-11-10 2005-05-10 Schering Corporation Nucleic acids encoding a cytokine receptor complex
ES2338529T3 (es) 2000-11-17 2010-05-10 Vascular Biogenics Ltd. Prometores que exiben especificidad por celulas endoteliales y metodos para su utilizacion.
US8071740B2 (en) 2000-11-17 2011-12-06 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis
IL156015A0 (en) 2000-11-24 2003-12-23 Vascular Biogenics Ltd Methods employing and compositions containing defined oxidized phospholipids for prevention and treatment of atherosclerosis
US20020172980A1 (en) * 2000-11-27 2002-11-21 Phan Brigitte Chau Methods for decreasing non-specific binding of beads in dual bead assays including related optical biodiscs and disc drive systems
US20030003464A1 (en) * 2000-11-27 2003-01-02 Phan Brigitte C. Dual bead assays including optical biodiscs and methods relating thereto
US20040248093A1 (en) * 2000-11-27 2004-12-09 Coombs James Howard Magneto-optical bio-discs and systems including related methods
WO2002044366A2 (fr) * 2000-11-29 2002-06-06 Lynkeus Biotech Gmbh Nouvelles proteines humaines specifiques de la retine c7orf9, c12orf7, mpp4 et f379
WO2002043651A2 (fr) * 2000-11-30 2002-06-06 Yeda Research And Development Co. Ltd. Methodes d'utilisation de lymphocytes t mis en culture et n'induisant pas de reaction du greffon contre l'hote (gvhd) pour traiter des maladies
EP2357478A3 (fr) 2000-11-30 2011-11-16 Crawford Healthcare Holdings Limited Diagnostic de maladie
US20020165149A1 (en) * 2000-12-08 2002-11-07 Kranz David M. Mutated class II major histocompatibility proteins
US7087395B1 (en) 2001-01-16 2006-08-08 Quest Diagnostics Investments Incorporated Vitamin D assay
GB0101762D0 (en) * 2001-01-23 2001-03-07 Medical Res Council Method
CA2475021A1 (fr) * 2001-01-31 2002-08-08 Dror Mevorach Induction de tolerance par des cellules apoptotiques et/ou necrotiques
US20050202098A1 (en) 2001-01-31 2005-09-15 Tolaren Disease therapy using dying or dead cells
JP2004537506A (ja) 2001-03-01 2004-12-16 ホリス − イーデン ファーマスーティカルズ、 インコーポレイテッド 血液細胞欠乏症を治療するためのある種のステロイドの使用
EP1385829A4 (fr) 2001-03-12 2005-10-19 Affymetrix Inc Composes de marquage d'acide nucleique
US20030104410A1 (en) * 2001-03-16 2003-06-05 Affymetrix, Inc. Human microarray
US20030003454A1 (en) 2001-03-23 2003-01-02 Yeda Research And Development Co. Ltd. At The Weizmann Institute Of Science Methods and kits for determining a risk to develop cancer, for evaluating an effectiveness and dosage of cancer therapy and for correlating between an activity of a DNA repair enzyme and a cancer
US20030220475A1 (en) * 2001-04-03 2003-11-27 Fields Howard A. Neutralizing immunogenic hev polypepetides
US7618789B2 (en) * 2001-04-06 2009-11-17 The United States Of America As Represented By The Secretary Of Department Of Health And Human Services Use of semenogelin in the diagnosis, prognosis and treatment of cancer
US20110313230A1 (en) 2001-05-11 2011-12-22 Terrance Grant Johns Specific binding proteins and uses thereof
DK1392359T4 (da) 2001-05-11 2013-06-10 Ludwig Inst For Cancer Res Ltd Specifikke bindingsproteiner og deres anvendelser.
US20100056762A1 (en) 2001-05-11 2010-03-04 Old Lloyd J Specific binding proteins and uses thereof
WO2002094123A2 (fr) 2001-05-18 2002-11-28 Danisco A/S Procede permettant d'ameliorer la qualite de la pate et du pain
US7132401B2 (en) 2001-05-22 2006-11-07 Merck & Co., Inc. Beta-secretase substrates and uses thereof
US20090324612A1 (en) * 2001-06-05 2009-12-31 Kaufman Daniel L Modulating neuronal outgrowth via the major histocompatibility complex class i (mhc i) molecule
US7553484B2 (en) * 2001-06-05 2009-06-30 The Regents Of The University Of California Modulating neuronal outgrowth via the major histocompatibility complex class I (MHC I) molecule
US6770622B2 (en) 2001-06-08 2004-08-03 Gary A. Jarvis N-terminally truncated galectin-3 for use in treating cancer
US20070190534A1 (en) * 2001-06-11 2007-08-16 Genesis Genomics Inc. Mitochondrial sites and genes associated with prostate cancer
IL159944A0 (en) * 2001-07-19 2004-06-20 Yissum Res Dev Co Polypeptides having carotenoid isomerase catalytic activity, nucleic acids encoding same and uses thereof
US6833441B2 (en) 2001-08-01 2004-12-21 Abmaxis, Inc. Compositions and methods for generating chimeric heteromultimers
DE60237696D1 (de) * 2001-08-01 2010-10-28 Univ Utah Am n-terminus trunkierte isoformen von zyklischen phosphodiesterasen pde3a
US20030082596A1 (en) * 2001-08-08 2003-05-01 Michael Mittmann Methods of genetic analysis of probes: test3
US20060073530A1 (en) * 2001-08-15 2006-04-06 Olaf Schneewind Methods and compositions involving sortase B
AU2002330724A1 (en) 2001-08-16 2003-03-10 Bar Ilan University Diagnosis, prevention and treatment of cancer
US20040136972A1 (en) 2001-09-07 2004-07-15 Yeda Research And Development Co. Ltd. Methods of treating disease by transplantation of developing allogeneic or xenogeneic organs or tissues
US7138144B2 (en) * 2001-09-07 2006-11-21 Nadir Askenasy Method of inducing immune tolerance via blood/lymph flow-restricted bone marrow transplantation
DE60233744D1 (de) 2001-09-20 2009-10-29 Univ Texas Bestimmung der zirkulierenden therapeutischen antikörper, antigene sowie antigen-antikörper-komplexe mit elisa-tests
US7393696B2 (en) * 2001-09-28 2008-07-01 Aspenbio Pharma, Inc. Bovine pregnancy test
US7521053B2 (en) 2001-10-11 2009-04-21 Amgen Inc. Angiopoietin-2 specific binding agents
US7138370B2 (en) 2001-10-11 2006-11-21 Amgen Inc. Specific binding agents of human angiopoietin-2
JP4381140B2 (ja) 2001-10-12 2009-12-09 シェーリング コーポレイション 免疫応答を調節するための二重特異性抗体の使用
EP1436313B1 (fr) 2001-10-19 2010-09-22 Vascular Biogenics Ltd. Constructions de polynucleotides, compositions pharmaceutiques et procedes de regulation negative de l'angiogenese et de therapie anticancereuse
US7175983B2 (en) * 2001-11-02 2007-02-13 Abmaxis, Inc. Adapter-directed display systems
AU2002366097B2 (en) 2001-11-20 2008-09-18 Monsanto Technology Llc Compositions and methods for accurate early pregnancy diagnosis
US6952704B2 (en) * 2001-11-26 2005-10-04 Microsoft Corporation Extending a directory schema independent of schema modification
US8178128B2 (en) * 2001-12-05 2012-05-15 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Nanoparticles containing polymeric nucleic acid homologs
WO2003054155A2 (fr) * 2001-12-19 2003-07-03 Bristol-Myers Squibb Company Pichia pastoris formate deshydrogenase et ses utilisations
US20050085432A1 (en) * 2001-12-26 2005-04-21 Aviva Lapidot Methods of using conjugates of saccharides and acetamidino or guanidino compounds for treating bacterial infections
US7341844B2 (en) * 2002-01-16 2008-03-11 Regents Of The University Of Minnesota Methods for diagnosing autism
IL152904A0 (en) 2002-01-24 2003-06-24 Gamida Cell Ltd Utilization of retinoid and vitamin d receptor antagonists for expansion of renewable stem cell populations
US8071096B2 (en) 2002-01-25 2011-12-06 G2 Therapies Ltd Anti-C5aR antibodies and uses thereof
EP1465982A4 (fr) 2002-01-25 2006-06-07 Gamida Cell Ltd Methodes de developpement de cellules souches et de cellules precurseurs, populations de cellules multipliees obtenues a l'aide de ces methodes
US7781396B2 (en) * 2002-01-31 2010-08-24 Tel Aviv University Future Technology Development L.P. Peptides directed for diagnosis and treatment of amyloid-associated disease
US20040052928A1 (en) * 2002-09-06 2004-03-18 Ehud Gazit Peptides and methods using same for diagnosing and treating amyloid-associated diseases
MXPA04007426A (es) 2002-02-01 2004-10-11 Schering Corp Usos de citosina de mamifero; reactivos relacionados.
US6992176B2 (en) * 2002-02-13 2006-01-31 Technion Research & Development Foundation Ltd. Antibody having a T-cell receptor-like specificity, yet higher affinity, and the use of same in the detection and treatment of cancer, viral infection and autoimmune disease
AU2003216341A1 (en) * 2002-02-20 2003-09-09 Dyax Corporation Mhc-peptide complex binding ligands
US7375206B2 (en) 2002-02-22 2008-05-20 The United States Of America As Represented By The Department Of Health And Human Services Brother of the regulator of imprinted sites (BORIS)
US7053188B2 (en) 2002-02-22 2006-05-30 Purdue Research Foundation Monoclonal antibodies specific for neoplasia-specific NADH:disulfide reductase
JP2005520511A (ja) * 2002-03-18 2005-07-14 ガミダ セル リミテッド エクスビボ拡大培養された幹細胞における分化を誘導する方法
US20030182669A1 (en) * 2002-03-19 2003-09-25 Rockman Howard A. Phosphoinositide 3-kinase mediated inhibition of GPCRs
US7611723B2 (en) * 2002-03-26 2009-11-03 Nanocyte Inc. Stinging cells expressing an exogenous polynucleotide encoding a therapeutic, diagnostic or a cosmetic agent and methods compositions and devices utilizing such stinging cells or capsules derived therefrom for delivering the therapeutic, diagnostic or cosmetic agent into a tissue
US7332585B2 (en) 2002-04-05 2008-02-19 The Regents Of The California University Bispecific single chain Fv antibody molecules and methods of use thereof
US7534580B2 (en) * 2002-05-01 2009-05-19 Ambrilia Biopharma Inc. PSP94 diagnostic reagents and assays
CA2391438A1 (fr) * 2002-05-01 2003-11-01 Procyon Biopharma Inc. Reactifs et methodes diagnostiques a base de psp94
CA2484676A1 (fr) 2002-05-03 2003-11-13 Sequenom, Inc. Muteines de proteines d'ancrage de kinase, leurs peptides, et procedes associes
US20040121442A1 (en) * 2002-05-05 2004-06-24 Ilan Chet Fungal chitinase, polynucleotide sequences encoding same, promoters of same, and uses thereof
US7528116B2 (en) 2002-05-30 2009-05-05 Memorial Sloan Kettering Cancer Center Kinase suppressor of Ras inactivation for therapy of Ras mediated tumorigenesis
CA2492631C (fr) * 2002-05-31 2013-03-12 Genetic Technologies Limited Anticorps maternels servant de marqueurs de cellules foetales permettant d'identifier et d'enrichir les cellules foetales du sang maternel
US7290215B2 (en) * 2002-06-03 2007-10-30 Microsoft Corporation Dynamic wizard interface system and method
JP2005533102A (ja) * 2002-07-12 2005-11-04 イッサム リサーチ ディベロップメント カンパニー オブ ザ ヘブリュー ユニバーシティー オブ エルサレム 微小器官によって生物学的プロセスを誘発する方法と装置
US7504215B2 (en) 2002-07-12 2009-03-17 Affymetrix, Inc. Nucleic acid labeling methods
EP1636561B1 (fr) 2002-07-15 2011-02-09 Board Of Regents, The University Of Texas System Criblage combinatoire de banques de proteines par expression periplasmique
DE60335383D1 (de) 2002-07-15 2011-01-27 Univ Texas Antikörper mit bindung an anionische phospholipide und aminophospholipide und ihre verwendung bei der behandlung von virusinfektionen
US7794716B2 (en) 2002-07-25 2010-09-14 Glenveigh Pharmaceuticals, Llc Antibody composition and passive immunization against pregnancy-induced hypertension
CA2494348C (fr) 2002-08-01 2014-04-08 Yeda Research And Development Co. Ltd. Methode et composition pour la protection du tissu neuronal contre une lesion induite par des taux de glutamate eleves
ATE469913T1 (de) * 2002-08-10 2010-06-15 Univ Yale Antagonisten des nogo-rezeptors
WO2004019953A1 (fr) 2002-08-28 2004-03-11 Hollis-Eden Pharmaceuticals, Inc. Procedes de traitement therapeutique
BR0314155A (pt) 2002-09-09 2005-07-05 Arbor Vita Corp Métodos para diagnosticar câncer cervical
AU2003273633A1 (en) 2002-09-26 2004-04-19 K.U.Leuven Research And Development Integrase cofactor
US7267981B2 (en) 2002-10-07 2007-09-11 Technion Research & Development Foundation Ltd. Human foreskin fibroblasts for culturing ES cells
KR20050059294A (ko) 2002-10-24 2005-06-17 스테릭스 리미티드 11-베타-하이드록시 스테로이드 데하이드로게나제 형태 1및 형태 2의 억제제
WO2004037204A2 (fr) * 2002-10-25 2004-05-06 University Of South Florida Methodes et composes de perturbation de la signalisation cd40r/cd40l dans le traitement de la maladie d'alzheimer
WO2004040252A2 (fr) 2002-10-30 2004-05-13 Yissum Research Development Company Of The Hebrew University Of Jerusalem Molecules et leurs procedes d'utilisation pour la mesure de fer non lie par la transferrine
US20050054097A1 (en) * 2002-11-17 2005-03-10 Tony Peled EX-VIVO expansion of hematopoietic system cell populations in mononuclear cell cultures
ATE544354T1 (de) 2002-11-26 2012-02-15 Univ Chicago Vermeidung und behandlung von mikrobenübertragenen epithelerkrankungen
WO2004050826A2 (fr) * 2002-11-29 2004-06-17 Technion Research & Development Foundation Ltd. Procede de mise en culture dynamique de cellules souches embryonnaires
JP2006508662A (ja) 2002-12-04 2006-03-16 アプレラ コーポレイション ポリヌクレオチドの多重増幅
US7491699B2 (en) * 2002-12-09 2009-02-17 Ramot At Tel Aviv University Ltd. Peptide nanostructures and methods of generating and using the same
ES2355818T7 (es) 2002-12-12 2013-04-12 R.B.T. (Rakuto Bio Technologies) Ltd. Uso de lignina peroxidasa en el aclaramiento de la piel y el pelo
PT1572984E (pt) 2002-12-16 2016-06-03 Technion Res & Dev Foundation Sistema de cultura para células estaminais embrionárias humanas sem células alimentadoras e sem xeno
AU2002953431A0 (en) * 2002-12-19 2003-01-09 Murdoch University BmpB Novel Nucleotide and Amino Acid Sequences and Diagnostic and Therapeutic Uses Thereof
CA2512499A1 (fr) 2003-01-02 2004-07-22 Rappaport Family Institute For Research In The Medical Sciences Methodes de prediction de potentiel a tirer benefice d'un traitement antioxydant pour la prevention de maladies cardiovasculaires chez des patients hyperglycemiques
US20040229245A1 (en) * 2003-01-06 2004-11-18 Anton Bittner Methods and algorithms for performing quality control during gene expression profiling on DNA microarray technology
WO2004060791A1 (fr) 2003-01-07 2004-07-22 Ramot At Tel Aviv University Ltd. Nanostructures de peptides encapsulant une matiere etrangere ainsi que procede de fabrication correspondant
US7955814B2 (en) 2003-01-17 2011-06-07 Danisco A/S Method
US20050196766A1 (en) 2003-12-24 2005-09-08 Soe Jorn B. Proteins
EP2290085B1 (fr) 2003-01-17 2017-12-13 DuPont Nutrition Biosciences ApS Procédé pour la préparation in situ d'un émulsifiant dans un aliment
MXPA05007654A (es) * 2003-01-17 2005-09-30 Danisco Metodo.
EP1590438A2 (fr) * 2003-01-24 2005-11-02 Duke University Modeles de trafic modifies pour l'arrestine et les recepteurs couples a la proteine g par l'intermediaire d'une chimere d'arrestine-ubiquitine
AU2004243690A1 (en) * 2003-03-03 2004-12-09 Burstein Technologies, Inc. Methods and apparatus for use in detection and quantitation of various cell types and use of optical bio-disc for performing same
EP1599598A4 (fr) 2003-03-04 2007-08-08 Yeda Res & Dev Polypeptides pon, polynucleotides les codant et compositions et procedes utilisant ces derniers
EP1599608A4 (fr) * 2003-03-05 2007-07-18 Genetic Technologies Ltd Identification d'adn foetal et de marqueurs de cellule foetale dans du plasma ou du serum maternel
EP1601759A4 (fr) * 2003-03-07 2007-02-14 Gamida Cell Ltd Extension de populations de cellules souches renouvelables au moyen de modulateurs de kinase pi 3
CA2558873C (fr) 2003-03-07 2015-10-20 New England Medical Center Hospitals, Inc. Traitement de maladies a depot d'iga1
US8017113B2 (en) 2003-03-12 2011-09-13 Rappaport Family Institute For Research In The Medical Sciences Compositions and methods for diagnosing and treating an inflammation
US7294701B2 (en) * 2003-04-02 2007-11-13 Technion Research & Development Foundation Ltd. Antibody fragment capable of modulating multidrug resistance and compositions and kits and methods using same
ATE517926T1 (de) 2003-04-04 2011-08-15 Yeda Res & Dev Antikörper zur hemmung der aktivität von mmp-2 und mmp-9
EP1611233B1 (fr) 2003-04-08 2016-01-06 Yeda Research And Development Co., Ltd. Cellules souches presentant une sensibilite accrue au sdf-1 et procedes pour leur obtention et utilisation
FR2853551B1 (fr) 2003-04-09 2006-08-04 Lab Francais Du Fractionnement Formulation stabilisante pour compositions d'immunoglobulines g sous forme liquide et sous forme lyophilisee
US20040209246A1 (en) * 2003-04-15 2004-10-21 Agouron Pharmaceuticals, Inc. Dual reporter/dye reduction methodology for evaluating antiviral and cytotoxicity of hepatitis C virus inhibitors
CN1832752A (zh) * 2003-04-16 2006-09-13 耶鲁大学 治疗淀粉样蛋白斑相关性病症的nogo－受体拮抗剂
US7321065B2 (en) * 2003-04-18 2008-01-22 The Regents Of The University Of California Thyronamine derivatives and analogs and methods of use thereof
US7554007B2 (en) 2003-05-22 2009-06-30 Evogene Ltd. Methods of increasing abiotic stress tolerance and/or biomass in plants
CA2978152C (fr) 2003-05-22 2021-01-26 Evogene Ltd. Procedes d'augmentation de la tolerance du stress abiotique des plantes et plantes ainsi produites
AU2005234725B2 (en) 2003-05-22 2012-02-23 Evogene Ltd. Methods of Increasing Abiotic Stress Tolerance and/or Biomass in Plants and Plants Generated Thereby
US20050020499A1 (en) * 2003-05-27 2005-01-27 Bar Ilan University Methods of attenuating cocaine seeking behavior employing glial cell-derived neurotrophic factor (GDNF) and pharmaceutical compositions and articles of manufacture suited for use in practice of the method
US8129514B2 (en) * 2003-06-19 2012-03-06 Evogene Ltd. Nucleotide sequences for regulating gene expression in plant trichomes and constructs and methods utilizing same
US7498428B2 (en) * 2003-06-19 2009-03-03 Evogene Ltd. Nucleotide sequences for regulating gene expression in plant trichomes and constructs and methods utilizing same
CN101415724B (zh) * 2003-06-30 2015-12-02 特拉维夫大学未来科技开发有限公司 肽、抗肽抗体以及用它们来诊断和治疗淀粉样蛋白相关疾病的方法
EP2128270B1 (fr) 2003-08-08 2012-10-03 Genenews Inc. Biomarqueurs d'ostéoarthrite et leur utilisations
US20050064479A1 (en) * 2003-08-12 2005-03-24 Affymetrix, Inc. Compounds and methods for post incorporation labeling of nucleic acids
AU2004267383A1 (en) * 2003-08-14 2005-03-03 The Bio Balance Corporation Bacterial strains, compositions including same and probiotic use thereof
EP1651674B1 (fr) 2003-08-14 2010-09-29 Exelixis, Inc. Ups utilises comme modificateurs de la voie de la beta catenine et leurs procedes d'utilisation
EP2280286A1 (fr) 2003-09-15 2011-02-02 Oklahoma Medical Research Foundation Procédé d'utilisation de dosages de cytokine pour diagnostiquer, traiter et évaluer le lupus érythémateux systémique
US20050064435A1 (en) * 2003-09-24 2005-03-24 Xing Su Programmable molecular barcodes
WO2005031362A2 (fr) 2003-10-02 2005-04-07 Ramot At Tel Aviv University Ltd. Nouveaux agents antibacteriens et procedes permettant de les identifier et de les utiliser
IL158287A0 (en) 2003-10-07 2004-05-12 Yeda Res & Dev Antibodies to nik, their preparation and use
JP4943848B2 (ja) 2003-10-07 2012-05-30 イエダ リサーチ アンド ディベロップメント カンパニー リミテッド Ｎｉｋに対する抗体、その調製および使用
US20060257429A1 (en) * 2003-10-23 2006-11-16 Dreier Kimberly J Vaccine for periodontal disease
US20050227251A1 (en) 2003-10-23 2005-10-13 Robert Darnell Method of purifying RNA binding protein-RNA complexes
PE20090047A1 (es) 2003-11-10 2009-01-26 Schering Corp Anticuerpo recombinante humanizado anti-interleuquina 10
WO2005051423A2 (fr) 2003-11-30 2005-06-09 Yeda Research And Development Co. Ltd Procedes et agents pour mettre en oeuvre une modulation immunitaire et procedes d'identification de modulateurs immunitaires
WO2005060368A2 (fr) 2003-12-10 2005-07-07 Millennium Pharmaceuticals, Inc. Anticorps humanises anti-ccr2 et leurs procedes d'utilisation
WO2005059100A2 (fr) * 2003-12-12 2005-06-30 New York University Procedes et compositions se rapportant a la cystatine c
US20100221233A1 (en) * 2003-12-15 2010-09-02 University Of South Florida Compositions and methods for enhancing neuroprotection via administration of stem cells and blood brain barrier permeabilizers
DK1722834T3 (da) 2003-12-22 2012-10-22 Regentis Biomaterials Ltd Matrix, som omfatter naturligt forekommende tværbundet proteinskelet
EP1708745B1 (fr) 2003-12-23 2012-04-18 Arbor Vita Corporation Anticorps pour des souches oncogenes du hpv et leurs methodes d'utilisation
GB0716126D0 (en) * 2007-08-17 2007-09-26 Danisco Process
US7718408B2 (en) * 2003-12-24 2010-05-18 Danisco A/S Method
CA2550800A1 (fr) 2003-12-24 2005-07-21 Danisco A/S Procedes pour produire des variantes de glycolipide-acyltransferase et des variantes de glycolipide-acyltransferase a activite amelioree a l'egard des glycolipides.
US8007847B2 (en) 2004-01-13 2011-08-30 Eytan Biderman Feeding formula appliance
US7423139B2 (en) * 2004-01-20 2008-09-09 Insight Biopharmaceuticals Ltd. High level expression of recombinant human erythropoietin having a modified 5′-UTR
US20050186646A1 (en) * 2004-01-26 2005-08-25 Cruz Miguel A. Rapid assay to detect ADAMTS-13 activity
EP1713900A4 (fr) * 2004-01-27 2009-06-17 Compugen Ltd Procedes et systemes pour l'annotation de sequences de biomolecules
EP1730173A4 (fr) * 2004-02-18 2008-10-08 Merck & Co Inc Molecules d'acide nucleique codant de nouvelles proteines murines a canal de calcium active faible tension, 1h alpha specialise, proteines codees et procedes d'utilisation de celles-ci
US7767792B2 (en) 2004-02-20 2010-08-03 Ludwig Institute For Cancer Research Ltd. Antibodies to EGF receptor epitope peptides
GB0403864D0 (en) 2004-02-20 2004-03-24 Ucl Ventures Modulator
EP1721011A1 (fr) 2004-03-01 2006-11-15 Applera Corporation Techniques, compositions et kits d'amplification de polynucleotide
CA2558478A1 (fr) 2004-03-02 2005-09-15 Acceleron Pharma Inc. Inhibiteurs d'alk7 et de la myostatine et leurs utilisations
US8352031B2 (en) 2004-03-10 2013-01-08 Impulse Dynamics Nv Protein activity modification
GB0405637D0 (en) 2004-03-12 2004-04-21 Danisco Protein
WO2005090406A2 (fr) 2004-03-12 2005-09-29 Vasgene Therapeutics, Inc. Compositions polypeptidiques pour inhiber l'angiogenese et la croissance tumorale
JP2007533755A (ja) * 2004-04-20 2007-11-22 ザ ユニヴァーシティ オヴ シカゴ 高分子量ｐｅｇ様化合物を含む治療薬送達システム
US8586294B2 (en) 2004-05-18 2013-11-19 The Board Of Trustees Of The Leland Stanford Junior University Detection of protein translocation by beta-galactosidase reporter fragment complementation
RU2381234C2 (ru) 2004-05-28 2010-02-10 Эдженсис, Инк. Антитела и родственные молекулы, связывающиеся с белками psca
BRPI0511395B1 (pt) 2004-06-14 2019-03-06 Evogene Ltd. Construção de ácido nucléico, e, método de melhoria do rendimento da fibra de uma planta produtora de fibra
US8034553B2 (en) 2004-06-24 2011-10-11 Kimberly-Clark Worldwide, Inc. Biomarkers for wound healing
ITBO20040412A1 (it) * 2004-07-01 2004-10-01 Eurodent Spa Lampada dentale particolarmente per ambulatori medico-dentistici
US8680062B2 (en) 2004-07-06 2014-03-25 Deliversir Ltd. System for delivering therapeutic agents into living cells and cells nuclei
WO2006006172A2 (fr) * 2004-07-15 2006-01-19 Ramot At Tel Aviv University Ltd. Utilisation d'agents anti-amyloides pour traiter et determiner des infections pathogenes
CN102533440B (zh) 2004-07-16 2017-09-19 杜邦营养生物科学有限公司 用酶使油脱胶的方法
US20090233986A1 (en) * 2004-07-27 2009-09-17 Mount Sinai School Of Medicine Methods and compositions for using sax2
US20090035784A1 (en) * 2004-07-30 2009-02-05 Mount Sinai School Of Medicine Of New York University Npc1l1 and npc1l1 inhibitors and methods of use thereof
US20060073168A1 (en) * 2004-08-11 2006-04-06 Stephens David S Neisseria meningitidis serogroup a capsular polysaccharide acetyltransferase, methods and compositions
CN102921019B (zh) 2004-08-26 2015-04-01 恩杰内克分子递送有限公司 通过细菌性来源的完整小细胞向哺乳动物细胞递送功能性核酸
FI20050753A7 (fi) 2004-09-03 2006-03-04 Licentia Oy Uudet peptidit
CN104644627A (zh) 2004-09-14 2015-05-27 科罗拉多大学董事会 基于基因靶向使用布新洛尔的治疗方法
WO2006030442A2 (fr) 2004-09-16 2006-03-23 Gamida-Cell Ltd. Methodes de culture ex vivo de cellules souches et de precurseur par co-culture avec des cellules mesenchymales
US10583094B2 (en) 2004-09-18 2020-03-10 University Of Maryland Therapeutic methods that target the NCCA-ATP channel
JP5085326B2 (ja) 2004-09-18 2012-11-28 ユニバーシティ オブ メリーランド，ボルチモア ＮＣＣａ−ＡＴＰチャネルを標的とする処置剤およびその使用方法
CA2580796C (fr) 2004-09-24 2013-03-26 Amgen Inc. Molecules fc modifiees ayant des peptides inserees dans les regions de boucle interne
CA2582051C (fr) 2004-09-29 2015-08-11 Collplant Ltd. Collagene de recombinaison produit dans une plante
WO2006035439A2 (fr) * 2004-09-29 2006-04-06 Yissum Research Development Company Of The Hebrew University Of Jerusalem Rnase t2 humaine recombinee et utilisations associees
GB0422052D0 (en) 2004-10-04 2004-11-03 Dansico As Enzymes
US7390489B2 (en) * 2004-10-08 2008-06-24 Komed Co., Ltd. Monoclonal antibody selectively recognizing listeria monocytogenes, hybridoma producing the antibody, test kit comprising the antibody and detection method of listeria monocytogenes using the antibody
EP1809374A4 (fr) * 2004-10-12 2008-09-10 Closed Loop Therapies Ltd Methodes et dispositifs implantables pour traiter des arythmies supraventriculaires
GB0423139D0 (en) * 2004-10-18 2004-11-17 Danisco Enzymes
JP5525689B2 (ja) * 2004-11-02 2014-06-18 ザ ガバメント オブ ザ ユナイテッド ステイツ オブ アメリカ アズ リプレゼンティッド バイ ザ セクレタリー デパートメント オブ ヘルス アンド ヒューマン サービシーズ 過剰増殖性障害を処置するための組成物および方法
GB0424940D0 (en) 2004-11-11 2004-12-15 Danisco Transcription factors
EP2302072B1 (fr) 2004-11-18 2012-03-14 Eppendorf Array Technologies S.A. PCR en temps réel de cibles sur un micro-réseau
EP2281841A3 (fr) 2004-12-03 2013-10-23 Merck Sharp & Dohme Corp. Biomarqueurs pour la présélection des patients pour la thérapie anti-IGF1R
WO2008109782A2 (fr) * 2007-03-06 2008-09-12 Cedars-Sinai Medical Center Diagnostic d'une affection abdominale inflammatoire chez l'enfant
US7504769B2 (en) * 2004-12-16 2009-03-17 E. I. Du Pont De Nemours + Company Aromatic chalcogen compounds and their use
US20060134680A1 (en) * 2004-12-22 2006-06-22 Alexander Kotlyar Homogeneous populations of nucleic acids, methods of synthesyzing same and uses thereof
JP2008529325A (ja) * 2005-01-16 2008-07-31 ズランゴー リミテッド 通信ネットワークシステムおよびそれを使用するための方法
US8375327B2 (en) 2005-01-16 2013-02-12 Zlango Ltd. Iconic communication
WO2007080558A2 (fr) * 2006-01-16 2007-07-19 Zlango Ltd. Systeme de reseau de communication et ses procedes d'utilisation
DK1843850T3 (en) 2005-01-31 2015-12-07 Realbio Technologies Ltd LATERAL FLOW STEERING CAPILLAR DEVICE
CN103497993A (zh) 2005-02-07 2014-01-08 基因信息公司 轻度骨关节炎生物标志物及其用途
EP1865935B1 (fr) 2005-02-17 2011-06-08 Hadasit Medical Research Services and Development Ltd. Bisphosphonates pour le traitement de l'endometriose
GB0503546D0 (en) * 2005-02-21 2005-03-30 Hellenic Pasteur Inst Antibody
US8216801B2 (en) 2005-02-25 2012-07-10 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization, (A.R.O.), The Volcani Center Methods for treating inflammatory disorders
US7695927B2 (en) * 2005-03-18 2010-04-13 Detroit R & D Detection of hypertension using glucuronidated metabolic products
EP3300739A3 (fr) 2005-03-31 2018-07-18 Agensys, Inc. Anticorps et molécules correspondantes se liant aux protéines 161p2f10b
US8124350B2 (en) 2005-04-04 2012-02-28 Biogen Idec Ma Inc. Methods and products for evaluating an immune response to a therapeutic protein
EP1874334A4 (fr) * 2005-04-15 2011-03-30 Vascular Biogenics Ltd Compositions contenant des peptides derives de la glycoproteine i beta 2 pour la prevention et le traitement de maladie cardiovasculaire
NZ562928A (en) 2005-04-18 2011-01-28 Mitomics Inc Mitochondrial mutations and rearrangements as a diagnostic tool for the detection of sun exposure, prostate cancer and other cancers
US20130022979A1 (en) 2005-04-18 2013-01-24 Genesis Genomics Inc. 3.4kb MITOCHONDRIAL DNA DELETION FOR USE IN THE DETECTION OF CANCER
US8834862B2 (en) * 2005-04-19 2014-09-16 Nanocyte Inc. Methods, compositions and devices utilizing stinging cells/capsules for conditioning a tissue prior to delivery of an active agent
AR053385A1 (es) 2005-05-12 2007-05-02 Novartis Ag Genes y proteinas novedosos de brachyspira hyodysenteriae y uso de los mismos para diagnostico y terapia
EP1888034A2 (fr) 2005-05-26 2008-02-20 Yissum Research Development Company, of The Hebrew University of Jerusalem Compositions et methodes d'utilisation desdites compositions dans l'administration d'agents dans un organe cible protege par une barriere sanguine
US20070021433A1 (en) 2005-06-03 2007-01-25 Jian-Qiang Fan Pharmacological chaperones for treating obesity
EP2465924A3 (fr) 2005-06-16 2013-01-02 Ramot at Tel-Aviv University Ltd. Cellules isolées et populations les comportant pour le traitement des maladies du SNC
EP3042963A1 (fr) 2005-06-20 2016-07-13 Advanced Cell Diagnostics, Inc. Procédés de détection d'acides nucléiques dans des cellules individuelles et d'identification de cellules rares dans de grandes populations cellulaires hétérogènes
US20070225242A1 (en) * 2005-06-21 2007-09-27 The Board Of Trustees Of The Leland Stanford Junior University Method and composition for treating and preventing tumor metastasis in vivo
AU2006267841B2 (en) * 2005-07-07 2011-12-15 Yissum Research Development Company Of The Hebrew University Of Jerusalem Nucleic acid agents for downregulating H19, and methods of using same
CA2613619A1 (fr) 2005-07-07 2007-01-18 Fulcrum Sp Ltd. Polypeptides sp1, polypeptides sp1 modifies et leurs utilisations
KR20080038131A (ko) 2005-07-18 2008-05-02 프로탈릭스 리미티드 생물학적으로 활성인 거대분자의 점막 또는 장관 투여
EP2889041A1 (fr) 2005-07-26 2015-07-01 Rutgers, The State University of New Jersey Kit de réactifs pour dosage de la tuberculose
CA2615460A1 (fr) * 2005-08-08 2007-02-15 Onconon, Llc Compositions d'anticorps, methodes de traitement de maladie neoplasique et methodes de regulation de la fertilite
US8008453B2 (en) 2005-08-12 2011-08-30 Amgen Inc. Modified Fc molecules
EP2514315A3 (fr) 2005-08-24 2012-11-07 Yeda Research and Development Co. Ltd. Cellules tolerogeniques derivees de donneurs universels et destinees a induire une tolerance a la transplantation non syngenique
WO2007026353A2 (fr) 2005-08-29 2007-03-08 Technion Research & Development Foundation Ltd. Milieux de culture de cellules souches
ME02705B (fr) 2005-08-31 2017-10-20 Merck Sharp & Dohme Anticorps anti-il-23 obtenus par genie genetique
US7608395B2 (en) 2005-09-15 2009-10-27 Baylor Research Institute Systemic lupus erythematosus diagnostic assay
EP1926814B1 (fr) 2005-09-22 2010-04-28 Yissum Research Development Company, of The Hebrew University of Jerusalem Constructions d acide nucléique, compositions pharmaceutiques et procédés utilisant ces dernières dans le cadre des traitements anticancéreux
WO2007041340A2 (fr) * 2005-09-30 2007-04-12 The Trustees Of Columbia University In The City Of New York Cellules microfluidiques a arrangements paralleles de molecules d'adn individuelles
WO2007047408A2 (fr) * 2005-10-12 2007-04-26 Pathologica, Llc. Application de signature promac
US20070087437A1 (en) * 2005-10-14 2007-04-19 Jifan Hu Methods for rejuvenating cells in vitro and in vivo
US8249814B2 (en) 2005-10-21 2012-08-21 Genenews Inc. Method, computer readable medium, and system for determining a probability of colorectal cancer in a test subject
AU2006307457B2 (en) 2005-10-24 2012-03-22 Evogene Ltd. Isolated polypeptides, polynucleotides encoding same, transgenic plants expressing same and methods of using same
US7842823B2 (en) * 2005-10-27 2010-11-30 The Regents Of The University Of California Fluorogenic probes for reactive oxygen species
EP1948674A4 (fr) 2005-11-02 2009-02-04 Protiva Biotherapeutics Inc Molecules d'arnsi modifiees et utilisations de celles-ci
US20100028358A1 (en) 2005-11-07 2010-02-04 Wolfram Ruf Compositions and Methods for Controlling Tissue Factor Signaling Specificity
WO2007061684A1 (fr) 2005-11-18 2007-05-31 Board Of Regents, The University Of Texas System Quantification de proteines hybrides issues d'une translocation chromosomiques et de leur activite
ES2409128T3 (es) 2005-11-29 2013-06-25 Gamida Cell Ltd. Procedimientos de mejora de anidamiento e injerto de células madre
US8846393B2 (en) 2005-11-29 2014-09-30 Gamida-Cell Ltd. Methods of improving stem cell homing and engraftment
WO2007067968A2 (fr) 2005-12-08 2007-06-14 Novartis Ag Effets d'inhibiteurs de fgfr3 sur la transcription genetique
US20070134814A1 (en) * 2005-12-09 2007-06-14 Kajander E O Methods and compositions for the detection of calcifying nano-particles, identification and quantification of associated proteins thereon, and correlation to disease
EP2674440B1 (fr) 2005-12-16 2019-07-03 IBC Pharmaceuticals, Inc. Ensembles bioactifs à base d'immunoglobuline multivalent
CN102408470A (zh) 2005-12-23 2012-04-11 洛桑大学 用作神经递质分泌抑制剂和肌肉松弛诱导物的合成肽
US7465544B2 (en) * 2006-01-11 2008-12-16 Wisconsin Alumni Research Foundation Synthetic cofactor analogs of S-adenosylmethionine as ligatable probes of biological methylation and methods for their use
US8775526B2 (en) 2006-01-16 2014-07-08 Zlango Ltd. Iconic communication
EP2526968A3 (fr) 2006-01-27 2013-05-22 Biogen Idec MA Inc. Antagonistes du récepteur NOGO
US20070179094A1 (en) 2006-01-31 2007-08-02 Bayer Schering Pharma Ag Modulation of MDL-1 activity for treatment of inflammatory disease
US8048849B2 (en) 2006-02-03 2011-11-01 Modigene, Inc. Long-acting polypeptides and methods of producing same
US8759292B2 (en) 2006-02-03 2014-06-24 Prolor Biotech, Llc Long-acting coagulation factors and methods of producing same
US8476234B2 (en) 2006-02-03 2013-07-02 Prolor Biotech Inc. Long-acting coagulation factors and methods of producing same
US20150038413A1 (en) 2006-02-03 2015-02-05 Opko Biologics Ltd. Long-acting polypeptides and methods of producing and administering same
US9458444B2 (en) 2006-02-03 2016-10-04 Opko Biologics Ltd. Long-acting coagulation factors and methods of producing same
US20140113860A1 (en) 2006-02-03 2014-04-24 Prolor Biotech Ltd. Long-acting polypeptides and methods of producing and administering same
US10351615B2 (en) 2006-02-03 2019-07-16 Opko Biologics Ltd. Methods of treatment with long-acting growth hormone
US8450269B2 (en) 2006-02-03 2013-05-28 Prolor Biotech Ltd. Long-acting growth hormone and methods of producing same
US9249407B2 (en) 2006-02-03 2016-02-02 Opko Biologics Ltd. Long-acting coagulation factors and methods of producing same
US8048848B2 (en) 2006-02-03 2011-11-01 Prolor Biotech Ltd. Long-acting interferons and derivatives thereof and methods thereof
US8946155B2 (en) 2006-02-03 2015-02-03 Opko Biologics Ltd. Long-acting polypeptides and methods of producing and administering same
US7553941B2 (en) 2006-02-03 2009-06-30 Modigene Inc Long-acting polypeptides and methods of producing same
US10221228B2 (en) 2006-02-03 2019-03-05 Opko Biologics Ltd. Long-acting polypeptides and methods of producing and administering same
US20090197286A1 (en) 2006-02-06 2009-08-06 Rappaport Family Institute For Research In The Med Methods and Kit for Diagnosing T1DM
SI1986661T1 (sl) 2006-02-08 2018-12-31 Genzyme Corporation Genska terapija za Niemann-Pickovo bolezen tipa A
SG169395A1 (en) 2006-02-09 2011-03-30 Univ South Florida Detection of cancer by elevated levels of bcl-2
HUE047230T2 (hu) 2006-02-28 2020-04-28 Biogen Ma Inc Gyulladásos és autoimmun betegségek natalizumabbal való kezelésének módszerei
KR20080104343A (ko) 2006-03-03 2008-12-02 엘란 파마슈티칼스, 인크. 나탈리주마브로 염증 및 자가면역 질환을 치료하는 방법
CA2641954C (fr) 2006-03-06 2016-04-26 Zetiq Technologies Ltd. Procedes et compositions pour identifier un phenotype cellulaire
WO2007109733A2 (fr) 2006-03-21 2007-09-27 The Johns Hopkins University Marqueurs de diagnostic et de pronostic et strategies de traitement de la sclerose en plaques
KR101490449B1 (ko) 2006-03-23 2015-02-05 플루리스템 리미티드 세포 증식 방법 및 세포의 용도 및 치료를 위해 그 세포에 의해 제조되는 조절된 배지
US20090226909A1 (en) 2006-03-28 2009-09-10 Tel Hashomer Medical Research Infrastructure And Services Ltd. Methods and kits for Determining Predisposition to Warfarin Resistance
US20070232556A1 (en) * 2006-03-31 2007-10-04 Montine Thomas J Methods and compositions for the treatment of neurological diseases and disorders
AU2007234733A1 (en) * 2006-04-07 2007-10-18 The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services Antibody compositions and methods for treatment of neoplastic disease
WO2007121522A1 (fr) 2006-04-21 2007-11-01 Minister for Primary Industries For And On Behalf Of The State Of New South Wales Especes de pestivirus
FR2900341B1 (fr) 2006-04-27 2012-09-14 Centre Nat Rech Scient Utilisation de ligands synthetiques multivalents de la nucleoline de surface pour le traitement du cancer
EP2021495A4 (fr) * 2006-05-09 2009-06-24 Musc Found For Res Dev Détection d'une insuffisance cardiaque diastolique par protéase et profilage plasmatique d'inhibiteur de protéase
WO2007136778A2 (fr) * 2006-05-19 2007-11-29 Teva Pharmaceutical Industries, Ltd. Protéines de fusion, leurs utilisations et leurs procédés de production
US20100196336A1 (en) 2006-05-23 2010-08-05 Dongsu Park Modified dendritic cells having enhanced survival and immunogenicity and related compositions and methods
US20070281883A1 (en) * 2006-06-05 2007-12-06 Hanna Rosenfeld Development of follicle stimulating hormone agonists and antagonists in fish
JP5385135B2 (ja) 2006-07-03 2014-01-08 チャールズ デイビッド アデア， 細胞接着分子の発現を調節するための組成物
US20080026394A1 (en) * 2006-07-11 2008-01-31 Antara Biosciences Inc. Methods of detecting one or more cancer markers
MX2009000059A (es) * 2006-07-11 2009-04-28 Musc Found For Res Dev Prediccion de falla del corazon despues del infarto al miocardio mediante el perfil de la proteasa y el inhibidor de proteasa.
PL2046762T3 (pl) 2006-07-14 2011-07-29 Chemocentryx Inc Triazolilofenylobenzenosulfonamidy
EP2046109A4 (fr) 2006-07-20 2010-01-06 Yeda Res & Dev Organismes photosynthetiques, compositions et procedes de generation desdits organismes
WO2008021954A2 (fr) * 2006-08-09 2008-02-21 Biogen Idec Ma Inc. Procédé de distribution d'un médicament
JP2008043332A (ja) 2006-08-17 2008-02-28 Panomics Inc 組織スライドからの核酸定量
ZA200900954B (en) * 2006-08-22 2010-05-26 G2 Inflammation Pty Ltd Ant-C5aR antibodies with improved properties
EP2061900A2 (fr) 2006-08-25 2009-05-27 Oncotherapy Science, Inc. Marqueurs pronostiques et cibles thérapeutiques s'appliquant au cancer du poumon
US8809052B2 (en) 2006-08-28 2014-08-19 Yeda Research And Development Co. Ltd. Methods of generating mature oligodendrocytes
JP2008111824A (ja) * 2006-09-01 2008-05-15 Nox Technologies Inc 腫瘍特異的ｔＮＯＸアイソフォーム及び方法
US7951776B2 (en) 2006-09-01 2011-05-31 American Type Culture Collection Methods for treatment of type 1 diabetes
US7985542B2 (en) * 2006-09-07 2011-07-26 Institut Pasteur Genomic morse code
WO2008031051A2 (fr) 2006-09-08 2008-03-13 United Therapeutics Corporation Diagnostic clinique d'une fibrose hépatique en utilisant une nouvelle numération globulaire de biomarqueurs de protéines du sérum humain
US8050516B2 (en) * 2006-09-13 2011-11-01 Fluidigm Corporation Methods and systems for determining a baseline during image processing
US8055034B2 (en) 2006-09-13 2011-11-08 Fluidigm Corporation Methods and systems for image processing of microfluidic devices
CN101595251B (zh) 2006-10-05 2014-06-11 技术研究及发展基金有限公司 微管及其制备方法
US7888059B2 (en) * 2006-10-05 2011-02-15 Yeda Research And Development Co. Ltd. Highly purified and stabilized Na,K-ATPase isoforms and methods of producing same
CA2665709C (fr) 2006-10-11 2018-04-03 Janssen Pharmaceutica N.V. Compositions et procedes pour le traitement et le diagnostic du syndrome du colon irritable
EP1912067A1 (fr) * 2006-10-12 2008-04-16 Eppendorf Array Technologies S.A. Procédé de quantification d'un composé cible issu d'un échantillon biologique à l'aide de puces à microreseau
EP2426199A3 (fr) 2006-10-20 2012-08-22 Danisco US Inc. Oxydases de polyol
EP2097750A2 (fr) * 2006-10-26 2009-09-09 Abbott Laboratories Analyse immunologique d'analytes dans des echantillons contenant des anticorps anti-analytes endogenes
US20080305512A1 (en) * 2006-10-26 2008-12-11 Mattingly Phillip G Assay for cardiac troponin autoantibodies
US7776605B2 (en) * 2006-10-26 2010-08-17 Abbott Laboratories Assay for cardiac troponin autoantibodies
EP2407783A1 (fr) 2006-10-27 2012-01-18 Janssen Pharmaceutica, N.V. Procédé de profilage pharmacologique de composés
EP2092074A4 (fr) 2006-11-02 2010-06-09 Univ Yale Estimation de la competence d'ovocytes
US8293684B2 (en) * 2006-11-29 2012-10-23 Exiqon Locked nucleic acid reagents for labelling nucleic acids
DK2102239T3 (da) 2006-11-30 2012-05-29 Res Dev Foundation Forbedrede immunoglobulin-biblioteker
US8473216B2 (en) * 2006-11-30 2013-06-25 Fluidigm Corporation Method and program for performing baseline correction of amplification curves in a PCR experiment
AR064333A1 (es) 2006-12-14 2009-04-01 Schering Corp Anticuerpo anti-tslp de diseno
BRPI0719602B1 (pt) * 2006-12-20 2021-05-18 Evogene Ltd construção de ácido nucléicos, e, métodos para aumentar biomassa de uma planta, para aumentar o vigor de uma planta, para aumentar o rendimento de uma planta, para aumentar a tolerância de uma planta ao stress abiótico, para aprimorar a qualidade de fibra e/ou rendimento de uma planta que produz fibra e para produzir fibras de algodão
US8506499B2 (en) * 2007-01-04 2013-08-13 Musc Foundation For Research Development Predicting atrial fibrillation recurrence by protease and protease inhibitor profiling
CN101688237A (zh) * 2007-01-11 2010-03-31 伊拉兹马斯大学医疗中心 环状染色体构象捕获（4c）
WO2008089103A2 (fr) 2007-01-12 2008-07-24 University Of Maryland, Baltimore Ciblage de canal ncca-atp destiné à protéger les organes après un épisode ischémique
EP2111449B1 (fr) * 2007-01-16 2012-03-07 Yissum Research Development Company of the Hebrew University of Jerusalem Agents nucléotidiques de silençage de h19 destinés au traitement de l'arthrite rhumatoïde
CA2673954C (fr) 2007-01-25 2015-09-15 Danisco A/S Production d'une lipide acyltransferase a partir de cellules transformees de bacillus licheniformis
US20100190662A1 (en) * 2007-01-26 2010-07-29 Rebecca Sutphen Methods and materials for detection, diagnosis and management of ovarian cancer
CN101657719A (zh) 2007-01-26 2010-02-24 路易斯维尔大学研究基金会公司 检测用于诊断和表征障碍的自身抗体的方法
US20100196403A1 (en) * 2007-01-29 2010-08-05 Jacob Hochman Antibody conjugates for circumventing multi-drug resistance
WO2008093341A2 (fr) 2007-01-31 2008-08-07 Technion Research & Development Foundation Ltd. Échafaudages électrofilés et leurs procédés de génération et d'utilisation
CA2676932C (fr) 2007-02-01 2015-11-24 Technion Research & Development Foundation Ltd. Fibres et tissus d'albumine et leurs procedes de generation et d'utilisation
PE20130588A1 (es) 2007-02-02 2013-05-21 Amgen Inc Hepcidina, antagonistas de la hepcidina y metodos de uso
US20080220498A1 (en) * 2007-03-06 2008-09-11 Cervin Marguerite A Variant Buttiauxella sp. phytases having altered properties
US8143046B2 (en) * 2007-02-07 2012-03-27 Danisco Us Inc., Genencor Division Variant Buttiauxella sp. phytases having altered properties
KR100855299B1 (ko) * 2007-02-16 2008-08-29 건국대학교 산학협력단 인간 ｉｌ-32 특이 항원결정기를 갖는 단일클론항체,특이항체분비 융합 세포주 및 항체들을 이용한 ｉｌ-32측정법
JP2008203195A (ja) * 2007-02-22 2008-09-04 Japan Science & Technology Agency Ｂｓｈの免疫測定用キットおよびｂｓｈの測定方法
CN103396489A (zh) 2007-02-23 2013-11-20 默沙东公司 工程改造的抗IL-23p19抗体
HUE042172T2 (hu) 2007-02-23 2019-06-28 Merck Sharp & Dohme Genetikailag elõállított anti-il-23P19 antitestek
EP2839839B1 (fr) 2007-02-28 2018-01-17 Yeda Research And Development Company Limited Sequences de ciblage du noyau
US20100105071A1 (en) * 2007-02-28 2010-04-29 Children's Medical Center Corporation Methods for predicting the onset of menarche
CA2679381A1 (fr) 2007-02-28 2008-09-04 Schering Corporation Anticorps anti-il-23r modifies
EP2136843A1 (fr) 2007-03-12 2009-12-30 Miraculins Inc. Biomarqueurs du cancer de la prostate et utilisations de ceux-ci
US8486640B2 (en) 2007-03-21 2013-07-16 Cedars-Sinai Medical Center Ileal pouch-anal anastomosis (IPAA) factors in the treatment of inflammatory bowel disease
CA2682093A1 (fr) 2007-03-29 2008-10-09 Technion Research & Development Foundation Ltd. Anticorps, procedes et kits de diagnostic et de traitement de melanomes
PT2865755T (pt) 2007-03-30 2017-05-26 Engeneic Molecular Delivery Pty Ltd Minicélulas intactas derivadas de bactéria compreendendo arn regulatório
JP2010523104A (ja) 2007-04-02 2010-07-15 ラモット・アット・テル・アビブ・ユニバーシテイ・リミテッド ガン細胞検出方法ならびにガン疾患の診断およびガン疾患の処置のモニタリングのためのその使用
WO2008124670A2 (fr) 2007-04-06 2008-10-16 Becton, Dickinson And Company Compositions et procédés pour l'identification d'un gène de carbapénèmase
CN101854798B (zh) 2007-04-09 2013-04-03 伊沃基因有限公司 用于增加植物的油含量、生长速率和/或产量的多核苷酸、多肽和方法
CA2683559C (fr) 2007-04-13 2019-09-24 Dana Farber Cancer Institute, Inc. Methodes de traitement d'un cancer resistant a des agents therapeutiques anti-erbb
WO2008127707A1 (fr) * 2007-04-13 2008-10-23 Dana Farber Cancer Institute, Inc. Établissement du profil de récepteurs tyrosine kinases
US8003314B2 (en) 2007-04-16 2011-08-23 Diagnostic Hybrids, Inc. Methods for direct fluorescent antibody virus detection in liquids
US9156865B2 (en) 2007-04-23 2015-10-13 Deliversir Ltd System for delivering therapeutic agents into living cells and cells nuclei
PL2144633T4 (pl) * 2007-04-23 2015-02-27 Sabag Rfa Ltd Układ do transportu czynników terapeutycznych do żywych komórek i jąder komórkowych
US9556210B2 (en) 2007-04-23 2017-01-31 Sabag-Rfa Ltd. System for delivering therapeutic agents into living cells and cells nuclei
US8338113B2 (en) 2007-05-01 2012-12-25 Tel Hashomer Medical Research Infrastructure And Services Ltd. Methods for detecting fetal cells in the maternal blood
US8629245B2 (en) 2007-05-01 2014-01-14 Research Development Foundation Immunoglobulin Fc libraries
AU2008275513A1 (en) * 2007-05-02 2009-01-15 Emory University Enhancement of glycoprotein incorporation into virus-like particles
CN101820910B (zh) 2007-05-03 2014-08-06 新加坡科技研究局 结合细胞内prl-1多肽或prl-3多肽的抗体
ES2660667T3 (es) 2007-05-07 2018-03-23 Protalix Ltd. Biorreactor desechable a gran escala
US20090081639A1 (en) * 2007-05-31 2009-03-26 Phil Hill Assay for sensitivity to chemotherapeutic agents
US7776877B2 (en) 2007-06-22 2010-08-17 Chemocentryx, Inc. N-(2-(hetaryl)aryl) arylsulfonamides and N-(2-(hetaryl) hetaryl arylsulfonamides
WO2009000089A1 (fr) * 2007-06-28 2008-12-31 University Of Saskatchewan Compositions immunomodulantes et procédés de traitement d'une maladie par des peptides de défense modifiés de l'hôte
WO2009009662A1 (fr) * 2007-07-10 2009-01-15 University Of South Florida Procédé de prédiction d'une non-réponse à une chimiothérapie de première intention
US20100197767A1 (en) 2007-07-11 2010-08-05 Lior Nissim Nucleic acid construct systems capable of daignosing or treating a cell state
CA2692761C (fr) 2007-07-12 2013-04-30 Chemocentryx, Inc. Heteroaryl-pyridyl- et phenyl-benzenesulfonamides condenses en tant que modulateurs du ccr2 pour le traitement de l'inflammation
AU2008277257B2 (en) 2007-07-15 2014-03-06 Hillman, Yitzchak Mr Disease treatment via antimicrobial peptides or their inhibitors
IL184627A0 (en) 2007-07-15 2008-12-29 Technion Res & Dev Foundation Agents for diagnosing and modulating metastasis and fibrosis as well as inflammation in a mammalian tissue
BR122020022199B1 (pt) 2007-07-24 2021-08-10 Evogene Ltd Método de aumento da tolerância de uma planta ao estresse abiótico, da biomassa e/ou produtividade de uma planta, e, construção de ácido nucleico isolado
US8293685B2 (en) 2007-07-26 2012-10-23 The Regents Of The University Of California Methods for enhancing bacterial cell display of proteins and peptides
CA2693310C (fr) * 2007-08-02 2018-11-27 Arresto Biosciences, Inc. Inhibiteurs de lox et loxl2, anticorps et utilisations associees
AU2007283667B2 (en) 2007-08-03 2014-09-04 Boehringer Ingelheim Vetmedica Gmbh Genes and proteins of Brachyspira hyodysenteriae and uses thereof
WO2009020923A1 (fr) 2007-08-03 2009-02-12 Musc Foundation For Research Development Anticorps monoclonaux humains et procédés de production
ES2453108T3 (es) 2007-08-06 2014-04-04 Orion Genomics, Llc Nuevos polimorfismos de un único nucleótido y combinaciones de polimorfismos nuevos y conocidos para determinar la expresión específica de alelo del gen IGF2
JP5548616B2 (ja) 2007-08-08 2014-07-16 ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム Ｖｅｇｆｒ−１／ｎｒｐ−１標的化ペプチド
WO2009023676A1 (fr) 2007-08-12 2009-02-19 Integrated Dna Technologies, Inc. Système de microréseau avec spécificité de séquence améliorée
US20090136916A1 (en) * 2007-08-13 2009-05-28 Trustees Of Tufts College Methods and microarrays for detecting enteric viruses
BRPI0814479A2 (pt) 2007-08-15 2016-07-12 Yeda Res & Dev "método para regular uma atividade de metaloproteinase 9 (mm9), método para identificar um agente capaz de regular especificamente a mmp-9, método de tratar a afecção clínica mediada pela mmp-9, molécula capaz de regular especificamente uma atividade da mmp-9, anticorpo humanizado e composição farmacêutica"
WO2009072001A2 (fr) * 2007-09-12 2009-06-11 Aurelium Biopharma Inc. Diagnostics dirigés contre slc9a3r1 pour une maladie néoplasique
WO2009034574A2 (fr) 2007-09-12 2009-03-19 Yeda Research And Development Co. Ltd. Procédés de traitement de tumeurs dans des sites privilégiés immunitairement
ES2392729T5 (es) 2007-09-19 2015-08-28 Pluristem Ltd. Células adherentes de tejidos adiposos o de placenta y uso de las mismas en terapia
EP3136103B1 (fr) 2007-10-05 2018-08-29 Affymetrix, Inc. Dosages hautement multiplexés
US8088735B2 (en) 2007-10-19 2012-01-03 Rappaport Family Institute For Research In The Medical Sciences Compositions comprising semaphorins for the treatment of angiogenesis related diseases and methods of selection thereof
WO2009069123A2 (fr) 2007-11-26 2009-06-04 Yissum Research Development Company Of The Hebrew University Of Jerusalem Compositions renfermant des polypeptides fibreux et des polysaccharides
US20110119791A1 (en) 2007-12-27 2011-05-19 Evogene Ltd. Isolated polypeptides, polynucleotides useful for modifying water user efficiency, fertilizer use efficiency, biotic/abiotic stress tolerance, yield and biomass in plants
US9006191B2 (en) 2007-12-27 2015-04-14 Protiva Biotherapeutics, Inc. Silencing of polo-like kinase expression using interfering RNA
WO2009102509A2 (fr) 2008-01-10 2009-08-20 Research Development Foundation Vaccins et diagnostics pour les ehrlichioses
EP2803675A3 (fr) 2008-01-25 2014-12-24 Amgen, Inc Anticorps anti-ferroportine et procédés d'utilisation
US20090233295A1 (en) * 2008-01-29 2009-09-17 Elias Georges Trim59 directed diagnostics for neoplastic disease
AU2009208607B2 (en) * 2008-01-31 2013-08-01 Compugen Ltd. Polypeptides and polynucleotides, and uses thereof as a drug target for producing drugs and biologics
EP2712620A1 (fr) 2008-02-07 2014-04-02 Cornell University Procédés de prévention ou de traitement de la résistance à l'insuline
JO2913B1 (en) 2008-02-20 2015-09-15 امجين إنك, Antibodies directed towards angiopoietin-1 and angiopoietin-2 proteins and their uses
CA2714296A1 (fr) 2008-02-20 2009-08-27 G2 Inflammation Pty Ltd Anticorps anti-c5ar humanises
US9469919B2 (en) 2008-02-21 2016-10-18 Technion Research & Development Foundation Ltd. Method of attaching a cell-of-interest to a microtube
EP2363407A1 (fr) 2008-02-28 2011-09-07 Murdoch University Nouvelles séquences de Brachyspira, compositions immunogènes, procédés pour leur préparation et utilisation
US20090311695A1 (en) * 2008-03-12 2009-12-17 Talat Nasim Method
AU2009227986C1 (en) 2008-03-27 2014-06-19 Murdoch University Novel sequences of Brachyspira, immunogenic compositions, methods for preparation and use thereof
NZ588658A (en) * 2008-03-28 2012-10-26 Mitomics Inc Aberrant mitochondrial dna, associated fusion transcripts and hybridization probes therefor
EP2107125A1 (fr) 2008-03-31 2009-10-07 Eppendorf Array Technologies SA (EAT) PCR en temps réel de cibles sur un micro-réseau
WO2009125395A1 (fr) * 2008-04-09 2009-10-15 Technion Research & Development Foundation Ltd. Anticorps antigrippe et leurs utilisations
WO2009125394A1 (fr) * 2008-04-09 2009-10-15 Technion Research & Development Foundation Ltd. Anticorps anti-immunodéficience humaine et leurs utilisations
US9132587B2 (en) * 2008-04-10 2015-09-15 Stratasys Ltd. System and method for three dimensional model printing
EP2279254B1 (fr) 2008-04-15 2017-07-05 Protiva Biotherapeutics Inc. Nouvelles formulations lipidiques pour l'administration d'acides nucléiques
WO2009129319A2 (fr) 2008-04-15 2009-10-22 Protiva Biotherapeutics, Inc. Réduction au silence de l'expression du gène csn5 au moyen d'arn interférant
GB0807161D0 (en) * 2008-04-18 2008-05-21 Danisco Process
US9095569B2 (en) 2008-04-18 2015-08-04 Collplant Ltd. Methods of generating and using procollagen
WO2009130695A2 (fr) 2008-04-21 2009-10-29 Danziger Innovation Ltd. Vecteurs d'expression de virus végétaux et leur utilisation pour générer des variations génotypiques dans des génomes de plantes
CN102066899A (zh) * 2008-04-23 2011-05-18 卢米耐克斯公司 建立针对生物来源之起始材料中多种分析物的标准品的方法
WO2009132124A2 (fr) 2008-04-24 2009-10-29 The Trustees Of Columbia University In The City Of New York Motifs géométriques et bicouches lipidiques utilisables pour l'organisation de molécules d'adn et leurs utilisations
WO2009133464A2 (fr) 2008-04-30 2009-11-05 Danisco A/S Procédé d'oxydation
WO2009139822A1 (fr) 2008-05-01 2009-11-19 Amgen Inc. Anticorps anti-hepcidine et méthodes d’utilisation associées
SG157299A1 (en) 2008-05-09 2009-12-29 Agency Science Tech & Res Diagnosis and treatment of kawasaki disease
MX2010012697A (es) 2008-05-22 2011-03-15 Evogene Ltd Polinucleotidos y polipeptidos aislados y metodos para usarlos para incrementar el rendimiento de plantas, biomasa, velocidad de crecimiento, vigor, contenido de aceite, tolerancia al estres abiotico de las plantas y eficiencia de uso de nitrogeno.
EP2291390B1 (fr) * 2008-05-22 2014-11-05 Centre National de la Recherche Scientifique (CNRS) Nouveaux composés optiquement purs pour une efficacité thérapeutique améliorée
EP2303293A1 (fr) 2008-05-27 2011-04-06 Pluristem Ltd. Procédés de traitement de maladies inflammatoires du côlon
ES2729557T3 (es) 2008-05-28 2019-11-04 Univ Ramot Células madre mesenquimatosas para el tratamiento de enfermedades del SNC
WO2009152102A2 (fr) * 2008-06-10 2009-12-17 The Regents Of The University Of California Sondes pro-fluorescentes
EP2326419B1 (fr) 2008-06-29 2021-04-07 Realbio Technologies Ltd. Dispositif de transfert de liquide particulièrement utile comme dispositif de capture dans un processus de dosage biologique
AU2009279458B2 (en) 2008-08-08 2015-07-02 Code Biotherapeutics, Inc. Long-acting DNA dendrimers and methods thereof
WO2010016806A1 (fr) 2008-08-08 2010-02-11 Agency For Science, Technology And Research (A*Star) Vhz pour le diagnostic et le traitement de cancers
US9018445B2 (en) 2008-08-18 2015-04-28 Evogene Ltd. Use of CAD genes to increase nitrogen use efficiency and low nitrogen tolerance to a plant
CA2735790C (fr) 2008-09-02 2017-02-28 Pluristem Ltd. Cellules adherentes provenant d'un tissu placentaire et leur utilisation en therapie
US8367392B2 (en) * 2008-09-05 2013-02-05 Transalgae Ltd. Genetic transformation of algal and cyanobacteria cells by microporation
WO2010029545A2 (fr) 2008-09-11 2010-03-18 Ben Gurion University Of The Negev Research And Development Authority Compositions et procédés destinés à traiter une infection par s. pneumoniae
CA2737193A1 (fr) 2008-09-12 2010-03-18 Universidade Federal De Sao Paulo - Unifesp Therapie cellulaire de tissus ischemiques
SG10201504623VA (en) 2008-09-24 2015-07-30 Tel Hashomer Medical Res Infrastructure & Services Ltd Peptides and compositions for prevention of cell adhesion and methods of using same
US9434985B2 (en) 2008-09-25 2016-09-06 University Of Massachusetts Methods of identifying interactions between genomic loci
WO2010035261A2 (fr) 2008-09-29 2010-04-01 Ben Gurion University Of The Negev Research And Development Authority Beta-peptides amyloides et procédés d'utilisation associés
US9207242B2 (en) 2008-10-09 2015-12-08 The University Of Hong Kong Cadherin-17 as diagnostic marker and therapeutic target for liver cancer
MX389590B (es) * 2008-10-30 2025-03-20 Evogene Ltd Polinucleotidos y polipeptidos aislados y metodos para utilizarlos para aumentar el rendimiento de la planta, biomasa, tasa de crecimiento, vigor, contenido de aceite, tolerancia al estres abiotico de las plantas y eficacia en el uso de nitrogeno.
CN102272157B (zh) 2008-11-07 2015-11-25 研究发展基金会 用于抑制cripto/grp78复合物形成和信号的组合物和方法
US20110229892A1 (en) 2008-11-17 2011-09-22 Yehuda G Assaraf Method for predicting a patient's responsiveness to anti-folate therapy
WO2010058396A1 (fr) 2008-11-19 2010-05-27 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Anticorps anti-cd44vra et procédés diagnostiques et thérapeutiques l'utilisant
WO2010061383A1 (fr) 2008-11-26 2010-06-03 Biodalia Microbiological Technologies Ltd. Procédé permettant d’enrichir in-situ des aliments avec des fructanes
US20110229471A1 (en) 2008-11-26 2011-09-22 Cedars-Sinai Medical Center Methods of determining responsiveness to anti-tnf alpha therapy in inflammatory bowel disease
WO2010064231A1 (fr) 2008-12-02 2010-06-10 Tel Hashomer Medical Research Infrastructure And Services Ltd. Procédés d’analyse d’édition d’arn a-i et constructions d’acide nucléique capables de ceux-ci
EP2370092A1 (fr) 2008-12-03 2011-10-05 Research Development Foundation Modulation de l'angiogenèse à médiation par olfml-3
US20120014927A1 (en) 2008-12-03 2012-01-19 Tel Hashomer Medical Research Infrastructure And Services Ltd. Methods and kits for determining predisposition to cancer
ES2554765T3 (es) 2008-12-05 2015-12-23 Yeda Research And Development Co. Ltd. miRNA-9 o miRNA-9* para uso en el tratamiento de ELA
NZ623273A (en) 2008-12-05 2015-09-25 Abraxis Bioscience Llc Sparc binding scfvs
WO2010066252A1 (fr) 2008-12-09 2010-06-17 Dako Denmark A/S Procédé d'évaluation de prétraitement
WO2010068757A1 (fr) 2008-12-12 2010-06-17 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Compositions et procédés utiles pour détecter et traiter des maladies associées à des ruptures du chromosome 16p
WO2010071610A1 (fr) 2008-12-19 2010-06-24 Agency For Science, Technology And Research (A*Star) Marqueurs biologiques de chikungunya sévère
WO2010075579A2 (fr) 2008-12-24 2010-07-01 Cedars-Sinai Medical Center Méthodes de prédiction de colite ulcéreuse réfractaire aux traitements (mr-uc) nécessitant une colectomie
SG172244A1 (en) 2008-12-29 2011-07-28 Tel Hashomer Medical Res Infrastructure & Services Ltd Peptides and compositions for prevention of cell adhesion and methods of using same
US20120009148A1 (en) 2008-12-29 2012-01-12 Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. Methods of predicting responsiveness to interferon treatment and treating hepatitis c infection
MX340023B (es) 2008-12-29 2016-06-22 Evogene Ltd Polinucleotidos, polipeptidos codificados, y metodos para utilizarlos para aumentar la tolerancia al estres abiotico, biomasa y/o rendimiento en plantas que los expresan.
WO2010076794A1 (fr) 2008-12-31 2010-07-08 Technion Research & Development Foundation Ltd. Procédé pour dénitrifier une saumure et systèmes aptes à une telle dénitrification
US9107935B2 (en) 2009-01-06 2015-08-18 Gilead Biologics, Inc. Chemotherapeutic methods and compositions
IL196820A0 (en) 2009-02-01 2009-11-18 Yissum Res Dev Co Devitalized, acellular scaffold matrices derived from micro-organs seeded with various cells
WO2010086867A2 (fr) 2009-02-02 2010-08-05 Ramot At Tel Aviv University Ltd. Peptides, compositions pharmaceutiques en contenant et leurs utilisations
WO2010089707A1 (fr) 2009-02-04 2010-08-12 Yeda Research And Development Co. Ltd. Procédé et trousses pour déterminer la sensibilité ou la résistance d'un cancer prostatique à une radiothérapie
IL313131A (en) 2009-02-11 2024-07-01 Caris Mpi Inc Molecular characterization of tumors
EP2396429B1 (fr) 2009-02-11 2015-05-27 Orion Genomics, LLC Combinaisons de polymorphismes destinées à déterminer l'expression spécifique des allèles d'igf2
WO2010093450A2 (fr) 2009-02-11 2010-08-19 Ludwing Institute For Cancer Research Ltd. Résistance assurée par la phosphorylation de pten au traitement du cancer et prognostic de patient modifié
US20110306069A1 (en) 2009-02-19 2011-12-15 Qingyu Wu Corin As A Marker For Heart Failure
EP2465920B1 (fr) 2009-02-26 2017-04-12 Tel HaShomer Medical Research Infrastructure and Services Ltd. Populations isolées de cellules souches rénales et procédés pour les isoler et les utiliser
LT3460062T (lt) 2009-03-02 2021-06-25 Evogene Ltd. Izoliuoti polinukleotidai ir polipeptidai, ir jų naudojimo būdai, skirti augalų derlingumui didinti ir (arba) žemės ūkio savybėms gerinti
CN102348720A (zh) 2009-03-09 2012-02-08 雷蒙特亚特特拉维夫大学有限公司 预防和治疗神经退行性疾病的组合物和方法
WO2010103517A1 (fr) 2009-03-12 2010-09-16 Rappaport Family Institute For Research In The Medical Sciences Compositions solubles pour le traitement de maladies associées aux ligands cxcr3
US20100240065A1 (en) * 2009-03-18 2010-09-23 Boehringer Ingelheim International Gmbh Prolyl Hydroxylase Compositions and Methods of Use Thereof
US8481698B2 (en) * 2009-03-19 2013-07-09 The President And Fellows Of Harvard College Parallel proximity ligation event analysis
AU2010241947B2 (en) 2009-03-27 2014-01-16 Gojo Industries, Inc. Compositions and methods for screening and using compounds antagonizing spore-surface interactions
RU2011137486A (ru) 2009-03-27 2013-05-10 Митомикс Инк. Аберрантная митохондриальная днк, ассоциированные с ней слитые транскрипты, продукты трансляции и гибрадизационные зонды
US20120020954A1 (en) 2009-03-30 2012-01-26 Anat Achiron Methods of predicting clinical course and treating multiple sclerosis
JP2012522762A (ja) 2009-04-01 2012-09-27 ザ メディカル リサーチ， インフラストラクチャー， アンド ヘルス サーヴィシーズ ファンド オブ ザ テル アヴィヴ メディカル センター ケラチノサイトの増殖および分化を調節する方法
WO2010116375A1 (fr) 2009-04-08 2010-10-14 Yeda Research And Development Co. Ltd. Peptides isolés pour réguler l'apoptose
AU2010239131A1 (en) 2009-04-21 2011-11-17 Genetic Technologies Limited Methods for obtaining fetal genetic material
GB0908770D0 (en) 2009-04-24 2009-07-01 Danisco Method
ES2668874T3 (es) 2009-04-30 2018-05-22 Tel Hashomer Medical Research Infrastructure And Services Ltd. Anticuerpos anti-CEACAM1 y métodos de uso de los mismos
CA2760569C (fr) 2009-05-01 2018-01-02 Dako Denmark A/S Nouveau cocktail d'anticorps
WO2010133967A1 (fr) * 2009-05-14 2010-11-25 University Of Oxford Diagnostic clinique d'une fibrose hépatique à l'aide d'un nouveau panel de biomarqueurs protéiques plasmatiques humains à faible abondance
US9182403B2 (en) 2009-05-19 2015-11-10 Zetiq Technologies Ltd. Kits for and methods of differential staining of cervical cancer cells and/or tissues
EP2432876A1 (fr) 2009-05-19 2012-03-28 Danisco A/S Utilisation
US20120128673A1 (en) 2009-05-20 2012-05-24 Schering Corporation Modulation of pilr receptors to treat microbial infections
WO2010137017A2 (fr) 2009-05-27 2010-12-02 Yeda Research And Development Co. Ltd. Inhibiteurs des protéasomes et leurs utilisations
WO2010137013A1 (fr) 2009-05-27 2010-12-02 Ramot At Tel Aviv University Ltd. Unités cristallisées de photosystème i dérivées du pois et leur utilisation dans des dispositifs solides
WO2010137021A2 (fr) 2009-05-27 2010-12-02 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Procédé de génération de tissu conjonctif
US20120070449A1 (en) 2009-05-28 2012-03-22 Yeda Research And Development Co. Ltd. Methods of treating inflammation
CN102439451B (zh) 2009-06-02 2014-12-03 德克萨斯大学系统董事会 患神经退行性疾病的对象中抗体所识别的小分子的鉴定
EP3626051A3 (fr) 2009-06-10 2020-04-22 Evogene Ltd. Polynucléotides et polypeptides isolés et leurs procédés d'utilisation pour augmenter l'efficacité d'utilisation, le rendement, la vitesse de croissance, la vigueur, la biomasse, la teneur en huile et/ou la tolérance au stress abiotique de l'azote
IN2012DN00715A (fr) 2009-06-24 2015-06-19 Health Corp Rambam
EP2446027A1 (fr) 2009-06-25 2012-05-02 Danisco A/S Protéine
EP2449107B1 (fr) 2009-06-29 2015-04-08 The University Of Western Australia Terpènes synthases issues du bois de santal
ES2613498T3 (es) 2009-07-01 2017-05-24 Protiva Biotherapeutics Inc. Nuevas formulaciones de lípidos para el suministro de agentes terapéuticos a tumores sólidos
US12203113B2 (en) 2009-07-09 2025-01-21 Opko Biologics Ltd. Long-acting coagulation factors and methods of producing same
US9663778B2 (en) 2009-07-09 2017-05-30 OPKO Biologies Ltd. Long-acting coagulation factors and methods of producing same
WO2011004379A1 (fr) 2009-07-10 2011-01-13 Tel Hashomer Medical Research Infrastructure And Services Ltd. Compositions et méthodes de traitement du cancer
SG10201700096VA (en) 2009-07-17 2017-02-27 Bioatla Llc Simultaneous, Integrated Selection And Evolution Of Antibody/Protein Performance And Expression In Production Hosts
WO2011011447A1 (fr) 2009-07-20 2011-01-27 Protiva Biotherapeutics, Inc. Compositions et méthodes pour rendre silencieuse l’expression du gène du virus ebola
CA2768725A1 (fr) 2009-07-21 2011-01-27 Tel Hashomer Medical Research Infrastructure And Services Ltd. Methode de diagnostic du cancer
GB0913442D0 (en) 2009-07-31 2009-09-16 Univ Ramot Cell-targeting nanoparticles comprising polynucleotide agents and uses thereof
WO2011021194A2 (fr) 2009-08-17 2011-02-24 Technion Research & Development Foundation Ltd. Cellules progénitrices de péricyte et leurs procédés de génération et d'utilisation
CA2771702A1 (fr) 2009-08-21 2011-02-24 Gilead Biologics, Inc. Domaines catalytiques provenant de la lysyle oxydase et de loxl2
WO2011021171A1 (fr) 2009-08-21 2011-02-24 Beeologics, Llc Prévention et traitement de maladies des insectes bénéfiques par l’intermédiaire de molécules transcrites végétales
US9642817B2 (en) 2009-08-27 2017-05-09 Technion Research & Development Foundation Limited Liposomal compositions and uses of same
IN2015DN02826A (fr) 2009-09-03 2015-09-11 Merck Sharp & Dohme
WO2011030336A1 (fr) 2009-09-08 2011-03-17 Ramot At Tel-Aviv University Ltd. Procédés de diagnostic de la sclérose latérale amyotrophique (sla)
EP2475381A2 (fr) 2009-09-08 2012-07-18 Yeda Research and Development Co. Ltd. Procédés pour la mobilisation de précurseur hématopoïétique
WO2011030329A1 (fr) 2009-09-10 2011-03-17 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Méthode de traitement de tumeurs
WO2011034950A1 (fr) 2009-09-16 2011-03-24 Vaxart, Inc. Stratégie d'immunisation pour empêcher une infection par le h1n1
WO2011033511A1 (fr) 2009-09-17 2011-03-24 Ramot At Tel-Aviv University Ltd. Peptides pour le traitement de troubles liés au stress oxydatif
EP2478093A2 (fr) 2009-09-17 2012-07-25 Yeda Research and Development Co. Ltd. Polypeptides pon1 isolés, polynucléotides codant pour ceux-ci et utilisations de ceux-ci dans le traitement ou la prévention des dommages associés à l'exposition à un organophosphate
US8735124B2 (en) 2009-09-17 2014-05-27 Yeda Research And Development Co. Ltd. Isolated PON1 polypeptides, polynucleotides encoding same and uses thereof in treating or preventing organophosphate exposure associated damage
WO2011038160A2 (fr) 2009-09-23 2011-03-31 Protiva Biotherapeutics, Inc. Compositions et procédés pour réduire au silence des gènes exprimés dans le cancer
WO2011038403A1 (fr) 2009-09-28 2011-03-31 Yuling Luo Procédés de détection de séquences d'acide nucléique à spécificité élevée
US20110076232A1 (en) 2009-09-29 2011-03-31 Ludwig Institute For Cancer Research Specific binding proteins and uses thereof
WO2011040973A2 (fr) 2009-10-02 2011-04-07 Ludwig Institute For Cancer Research Ltd. Immunoconjugués de tnf avec des anticorps de protéine d'activation des fibroblastes et procédés et utilisations de ceux-ci
US20110081706A1 (en) * 2009-10-02 2011-04-07 TransAlgae Ltd Method and system for efficient harvesting of microalgae and cyanobacteria
WO2011040972A1 (fr) 2009-10-02 2011-04-07 Ludwig Institute For Cancer Research Ltd. Anticorps dirigés contre la protéine d'activation du fibroblaste, et utilisations et procédés correspondants
WO2011044186A1 (fr) 2009-10-06 2011-04-14 The Board Of Trustees Of The University Of Illinois Récepteurs de lymphocytes t à chaîne unique humains
EP2485762B1 (fr) 2009-10-11 2017-12-13 Biogen MA Inc. Tests associés à un anti-vla-4
US8962584B2 (en) 2009-10-14 2015-02-24 Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. Compositions for controlling Varroa mites in bees
CN102906263B (zh) 2009-10-14 2017-05-31 耶路撒冷希伯来大学伊森姆研究发展公司 用于控制蜂中的瓦螨的组合物
US9109206B2 (en) 2009-10-16 2015-08-18 Rutgers, The State University Of New Jersey Method for treating chronic nerve tissue injury using a cell therapy strategy
US9476060B2 (en) 2009-10-21 2016-10-25 Danziger Innovations Ltd. Generating genotypic variations in plant genomes by gamete infection
CA2779223A1 (fr) 2009-10-27 2011-05-12 Caris Mpi, Inc. Profilage moleculaire pour medecine personnalisee
IL201999A (en) 2009-11-08 2017-10-31 Medical Res & Development Fund For Health Services Bnai Zion Medical Center The State Of Israel A knockout mouse of the 1 – mo gene, a gene associated with morbidly extreme obesity
WO2011058555A1 (fr) 2009-11-12 2011-05-19 Yeda Research And Development Co. Ltd. Procédé d'édition de l'adn dans une cellule et constructions ayant cette capacité
WO2011058557A1 (fr) 2009-11-12 2011-05-19 Ramot At Tel-Aviv University Ltd. Compositions contenant du pedf et leurs utilisations dans le traitement et la prévention de syndromes liés aux ovaires
WO2011058558A2 (fr) 2009-11-12 2011-05-19 Technion Research & Development Foundation Ltd. Milieu de culture, cultures de cellules et procédés de culture de cellules souches pluripotentes dans un état indifférencié
WO2011061736A1 (fr) 2009-11-17 2011-05-26 Protalix Ltd. Alpha galactosidase alcaline pour le traitement de la maladie de fabry
US8592151B2 (en) * 2009-11-17 2013-11-26 Musc Foundation For Research Development Assessing left ventricular remodeling via temporal detection and measurement of microRNA in body fluids
GB0920089D0 (en) 2009-11-17 2009-12-30 Danisco Method
US9260517B2 (en) 2009-11-17 2016-02-16 Musc Foundation For Research Development Human monoclonal antibodies to human nucleolin
EP2504472A1 (fr) 2009-11-24 2012-10-03 Collplant Ltd. Procédé de production de fibres de collagène
US9910040B2 (en) 2012-07-09 2018-03-06 Sevident, Inc. Molecular nets comprising capture agents and linking agents
US9733242B2 (en) 2012-10-07 2017-08-15 Sevident, Inc. Devices for capturing analyte
US9175262B2 (en) 2009-11-30 2015-11-03 Pluristerm Ltd. Adherent cells from placenta and use of same in disease treatment
US8835120B2 (en) * 2009-12-02 2014-09-16 Abbott Laboratories Assay for cardiac troponin-T (cTnT)
US8652788B2 (en) 2009-12-02 2014-02-18 Abbott Laboratories Assay for diagnosis of cardiac myocyte damage
US8183002B2 (en) 2009-12-03 2012-05-22 Abbott Laboratories Autoantibody enhanced immunoassays and kits
US20110136141A1 (en) 2009-12-03 2011-06-09 Abbott Laboratories Peptide reagents and method for inhibiting autoantibody antigen binding
US9562235B2 (en) 2009-12-06 2017-02-07 A.B. Seeds Ltd. MicroRNA compositions and methods for enhancing plant resistance to abiotic stress
WO2011072091A1 (fr) 2009-12-09 2011-06-16 Quark Pharmaceuticals, Inc. Méthodes et compositions utilisées pour le traitement de maladies, d'affections ou de lésions du snc
WO2011084357A1 (fr) 2009-12-17 2011-07-14 Schering Corporation Modulation de pilr pour le traitement de troubles immunitaires
GB0922377D0 (en) 2009-12-22 2010-02-03 Arab Gulf University The Mutant LDL receptor
BR112012016033B1 (pt) 2009-12-28 2021-03-09 Evogene Ltd. métodos de aumento de produção de semente, biomassa, taxa de crescimento, vigor, tolerância à deficiência de nitrogênio, eficiência no uso de nitrogênio e/ou redução do tempo de florescimento de uma planta, e, para produzir uma planta transgênica
US20130011376A1 (en) 2009-12-29 2013-01-10 Gamida Cell Ltd. Methods for Enhancing Natural Killer Cell Proliferation and Activity
MX342641B (es) 2010-01-05 2016-10-07 Vascular Biogenics Ltd Metodos para uso de un agente adenoviral anti-angiogenico especifico.
WO2011084882A2 (fr) 2010-01-05 2011-07-14 Contrafect Corporation Procédés et compositions pour une thérapie immunologique améliorée et le ciblage de bactéries à gram-positif
BR112012017014B1 (pt) 2010-01-11 2021-07-20 Biogen Ma Inc Métodos para detecção de anticorpos de vírus jc
US11287423B2 (en) 2010-01-11 2022-03-29 Biogen Ma Inc. Assay for JC virus antibodies
US20130052165A1 (en) 2010-01-12 2013-02-28 Livnat Bangio Methods of Producing Adenovirus Vectors and Viral Preparations Generated Thereby
CN102822202B (zh) 2010-01-27 2015-07-22 耶达研究及发展有限公司 抑制金属蛋白的抗体
EP2529030B1 (fr) 2010-01-29 2019-03-13 Advanced Cell Diagnostics, Inc. Methode de detection d'acides nucleiques in situ
US8574832B2 (en) 2010-02-03 2013-11-05 Massachusetts Institute Of Technology Methods for preparing sequencing libraries
BR112012019693A2 (pt) 2010-02-04 2017-06-20 Gilead Biologics Inc anticorpos que se ligam à lisil oxidase-like 2 (loxl2) e métodos de uso para eles.
BR112012019780A2 (pt) 2010-02-08 2020-09-01 Agensys, Inc. conjugados de fármaco e anticorpo (adc) que ligam a proteínas 161p2f10b
WO2011099006A2 (fr) 2010-02-11 2011-08-18 Yeda Research And Development Co. Ltd. Systèmes enzymatiques pour la fixation du carbone et procédés de production associés
AU2011219426A1 (en) 2010-02-24 2012-10-04 Ben Gurion University Of The Negev Research And Development Authority Methods for inhibiting necrosis
WO2011107939A1 (fr) 2010-03-01 2011-09-09 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Méthodes de prédiction de l'efficacité d'un traitement par anti-vegfa pour des tumeurs solides
WO2011107994A1 (fr) 2010-03-04 2011-09-09 Yeda Research And Development Co. Ltd. Procédés de mesure de la stabilité d'une protéine
KR101982126B1 (ko) 2010-03-08 2019-05-27 몬산토 테크놀로지 엘엘씨 식물에서 유전자 조절을 위한 폴리뉴클레오타이드 분자
US9267142B2 (en) 2010-03-08 2016-02-23 Yeda Research And Development Co. Ltd. Recombinant protein production in heterologous systems
US20120329089A1 (en) 2010-03-11 2012-12-27 Jacob Edrei Methods of generating hydrogen
WO2011114251A1 (fr) 2010-03-18 2011-09-22 Danisco A/S Produits alimentaires
EP2556085A2 (fr) 2010-04-05 2013-02-13 Bar-Ilan University Polypeptides formant des pores pouvant être activés par une protéase
US9125931B2 (en) 2010-04-06 2015-09-08 Massachusetts Institute Of Technology Post-transcriptional regulation of RNA-related processes using encoded protein-binding RNA aptamers
SG184466A1 (en) 2010-04-06 2012-11-29 Massachusetts Inst Technology Gene-expression profiling with reduced numbers of transcript measurements
WO2011128895A2 (fr) 2010-04-12 2011-10-20 Ben Gurion University Of The Negev Research And Development Authority Sulfotransférase d'une microalgue rouge et utilisations de celle-ci
WO2011128897A1 (fr) 2010-04-12 2011-10-20 Technion Research & Development Foundation Ltd. Population de cellules progénitrices pancréatiques et leurs méthodes d'isolement et d'utilisation
JP5786020B2 (ja) 2010-04-16 2015-09-30 アボットジャパン株式会社 関節リウマチを診断する方法および試薬
WO2011132182A1 (fr) 2010-04-18 2011-10-27 Yeda Research And Development Co. Ltd. Molécules et méthodes d'utilisation de celles-ci pour le traitement des maladies associées aux ligands erbb/erbb
US9328353B2 (en) 2010-04-28 2016-05-03 Evogene Ltd. Isolated polynucleotides and polypeptides for increasing plant yield and/or agricultural characteristics
US20130053277A1 (en) 2010-05-04 2013-02-28 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Methods of identifying inhibitors of polypeptides-of-interest
US9352000B2 (en) 2010-05-05 2016-05-31 Rappaport Family Institute For Research In The Medical Sciences Use of CCL1 in therapy
IL208820A0 (en) 2010-10-19 2011-01-31 Rachel Teitelbaum Biologic female contraceptives
JP2013525814A (ja) 2010-05-07 2013-06-20 アッヴィ・インコーポレイテッド 標的化チロシンキナーゼインヒビターでの治療に対する感受性の予測方法
US20120190563A1 (en) 2010-05-07 2012-07-26 Abbott Laboratories Methods for predicting sensitivity to treatment with a targeted tyrosine kinase inhibitor
CA2799307C (fr) 2010-05-13 2019-07-02 Tel Hashomer Medical Research Infrastructure And Services Ltd. Populations isolees de cellules renales adultes et procedes d'isolement et d'utilisation desdites populations
WO2011146479A1 (fr) 2010-05-18 2011-11-24 The Texas A&M University System Procédé et composition pour le diagnostic et le suivi de maladies inflammatoires
US9169329B2 (en) 2010-06-01 2015-10-27 Ludwig Institute For Cancer Research Antibodies directed to the receptor tyrosine kinase c-Met
CN103037891A (zh) 2010-06-03 2013-04-10 雷蒙特亚特特拉维夫大学有限公司 治疗糖尿病的方法和能够治疗糖尿病的组合物
KR20130123357A (ko) 2010-06-07 2013-11-12 오스나트 에슈어-파비안 저산소증과 관련된 질환의 진단방법 및 키트
EP2582842A2 (fr) 2010-06-16 2013-04-24 Yissum Research Development Company of The Hebrew University of Jerusalem Procédé de diagnostic et de traitement du cancer
US20130097731A1 (en) 2010-06-16 2013-04-18 Futuragene Israel Ltd. Pest-resistant plants containing a combination of a spider toxin and a chitinase
US20130316338A1 (en) 2010-06-29 2013-11-28 The United States Government As Represented By The Department Of Veterans Affairs CCR6 As A Biomarker of Alzheimer's Disease
GB201011513D0 (en) 2010-07-08 2010-08-25 Danisco Method
US9512188B2 (en) 2010-07-12 2016-12-06 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) Isolated polynucleotides and methods and plants using same for regulating plant acidity
EP2407242A1 (fr) 2010-07-13 2012-01-18 Dublin City University Analyse de clone directe et technologie de sélection
BR112013000984A2 (pt) 2010-07-15 2017-10-03 Technion Res & Dev Foundation Estrutura de ácido nucleico para o aumento da tolerância ao estresse abiótico em plantas
CA2805478A1 (fr) 2010-07-15 2012-01-19 Technion Research & Development Foundation Ltd. Entites de haute affinite isolees presentant une specificite de type recepteur des lymphocytes t pour les complexes natifs du mhc de classe ii et les peptides auto-antigeniques associes au diabete
EP2593551B1 (fr) 2010-07-15 2016-09-14 Technion Research & Development Foundation Ltd. Entités isolées à affinité élevée dotées d'une spécificité telle que celle des récepteurs de lymphocytes t pour des complexes natifs du cmh de classe ii et peptides auto-antigènes de la décarboxylase de l'acide glutamique (gad)
DK2593797T3 (da) 2010-07-16 2019-08-05 Bioatla Llc Hidtil ukendte fremgangsmåder til proteinevolution
US9677979B2 (en) 2010-07-16 2017-06-13 Vanderbilt University Low resource processor using surface tension valves for extracting, concentrating and detecting molecular species
EP2595637B1 (fr) 2010-07-22 2017-11-01 Cellect Biotherapeutics Ltd. Cellules immunitaires régulatrices possédant un effet de destruction cellulaire ciblé accru
JP5813111B2 (ja) 2010-07-23 2015-11-17 ルミネックス コーポレーション イムノアッセイにおける試薬の反応性を制御するためのコカップリング
US9120862B2 (en) 2010-07-26 2015-09-01 Abbott Laboratories Antibodies relating to PIVKA-II and uses thereof
US9144585B2 (en) 2010-07-27 2015-09-29 Technion Research & Development Foundation Limited Isolated mesenchymal progenitor cells and extracellular matrix produced thereby
JP2013535966A (ja) 2010-07-27 2013-09-19 テクニオン リサーチ アンド ディベロップメント ファウンデーション リミテッド 引き抜かれた毛包由来のケラチン生成細胞から誘導多能性幹細胞を生成させる方法
WO2012014208A2 (fr) 2010-07-27 2012-02-02 Yeda Research And Development Co. Ltd. Procédés et systèmes d'estimation de la clonalité de cultures cellulaires
US8901074B2 (en) 2010-08-04 2014-12-02 Ramot At Tel-Aviv University Methods of treating autoimmune diseases of the central nervous system (CNS) and neurodegenerative diseases
US8956859B1 (en) 2010-08-13 2015-02-17 Aviex Technologies Llc Compositions and methods for determining successful immunization by one or more vaccines
WO2012025914A1 (fr) 2010-08-22 2012-03-01 Ramot At Tel-Aviv University Ltd. Cellules souches pluripotentes induites dérivées de cellules bêta pancréatiques humaines
WO2012025925A1 (fr) 2010-08-24 2012-03-01 Rappaport Family Institute For Research In The Medical Sciences Procédés d'amélioration de la transplantation en utilisant des sdf-1alpha
CA3158003A1 (fr) 2010-08-30 2012-03-08 Evogene Ltd. Polynucleotides et polypeptides isoles, et procedes les utilisant pour augmenter l'efficacite d'utilisation de l'azote, le rendement, la vitesse de croissance, la vigueur, la biom asse, la teneur d'huile, et/ou la tolerance aux stress abiotiques
WO2012032519A2 (fr) 2010-09-07 2012-03-15 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Méthodes de diagnostic de la maladie de parkinson
WO2012032510A1 (fr) 2010-09-07 2012-03-15 Yeda Research And Development Co. Ltd. Amorces pour l'amplification d'adn et procédés de sélection de ces dernières
CA3150342A1 (fr) 2010-09-07 2012-03-15 Technion Research & Development Foundation Limited Nouveaux procedes et milieux de culture destines a la culture de cellules souches pluripotentes
US20130164288A1 (en) 2010-09-07 2013-06-27 Protalix Ltd. Readthrough acetylcholinesterase (ache-r) for treating or preventing parkinson's disease
ES2589678T3 (es) 2010-09-08 2016-11-15 Yeda Research And Development Co. Ltd. Uso de linfocitos T de memoria central anti-terceros para el tratamiento anti-leucemia/linfoma
EP2614083A2 (fr) 2010-09-08 2013-07-17 Yeda Research and Development Co. Ltd Combinaison de médicaments immunosuppresseurs pour une prise de greffe à long terme et stable
CN103210082A (zh) 2010-09-15 2013-07-17 雷蒙特亚特特拉维夫大学有限公司 扩增胰岛β细胞和使其再分化的方法
US20120071343A1 (en) 2010-09-20 2012-03-22 Advanced Cell Diagnostics, Inc Biomarkers for differentiating melanoma from benign nevus in the skin
US20130210901A1 (en) 2010-09-20 2013-08-15 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Method of treating neurodegenerative diseases
ES2874306T3 (es) 2010-09-29 2021-11-04 Agensys Inc Conjugados de anticuerpos y fármacos (CAF) que se unen a las proteínas 191P4D12
EP2624848A2 (fr) 2010-10-04 2013-08-14 Centre National De La Recherche Scientifique CNRS Compositions comprenant des ligands synthétiques polyvalents de glycosaminoglycanes et de nucléoline
EP2441520A1 (fr) 2010-10-12 2012-04-18 Eppendorf AG Application en temps réel et détection basée sur un micro-réseau de cibles d'acides nucléiques dans un dosage sur puce de flux
EP2627766B1 (fr) 2010-10-17 2016-05-25 Yeda Research and Development Co. Ltd. Procédés et compositions utilisables en vue du traitement de pathologies médicales associées à l'insuline
WO2012052878A1 (fr) 2010-10-19 2012-04-26 Vascular Biogenics Ltd. Polynucléotides isolés et constructions d'acide nucléique pour diriger l'expression d'un gène d'intérêt dans des cellules
ES2562821T3 (es) 2010-10-21 2016-03-08 Advanced Cell Diagnostics, Inc. Método ultrasensible para la detección in situ de ácidos nucleicos
WO2012056452A2 (fr) 2010-10-27 2012-05-03 Nanocyte (Israel) Ltd. Compositions pharmaceutiques et dispositifs d'administration comprenant des cellules ou capsules urticantes
CN103370337B (zh) 2010-10-28 2015-12-09 耶达研究及发展有限公司 用于产生针对金属酶的抗体的方法
UY33705A (es) 2010-11-03 2012-04-30 Yissum Res Dev Co Plantas transgenicas con rendimientos de sacarificacion mejorados y metodos para generarlas
WO2012059925A2 (fr) 2010-11-04 2012-05-10 Ben-Gurion University Of The Negev Research And Development Authority Acyl-coa: gène de type diacylglycérol acyltransférase 1 (ptdgat1) et utilisations de celui-ci
RU2013126706A (ru) 2010-11-15 2014-12-27 Рамот Ат Тель-Авив Юниверсити Лтд. Дипептидные аналоги для лечения состояний, ассоциированных с образованием амилоидных фибрилл
WO2012066495A2 (fr) 2010-11-17 2012-05-24 Ben Gurion University Of The Negev Research And Development Authority Thérapie à base de cellules t pour les maladies neurodégénératives
WO2012073238A1 (fr) 2010-12-02 2012-06-07 Technion Research & Development Foundation Ltd. Procédé de génération de cellules cornéennes et populations de cellules les comprenant
AU2011253984A1 (en) 2010-12-07 2012-06-28 Biobalance Llc Method For Identifying E. Coli M-17
CA2816495C (fr) 2010-12-15 2020-10-13 Kadimastem Ltd. Cellules produisant de l'insuline derivees de cellules souches pluripotentes
BR112013015830B8 (pt) 2010-12-22 2022-07-19 Evogene Ltd Método de aumento de produção, biomassa, taxa de crescimento, vigor, tolerância ao estresse abiótico, e/ou eficiência no uso de nitrogênio de uma planta, e, construção de ácido nucleico
AR084358A1 (es) 2010-12-27 2013-05-08 Lilly Co Eli Composiciones y metodos para identificar y diferenciar componentes virales de vacunas multivalentes de la “fiebre de embarque” (complejo de enfermedad respiratoria bovina (brdc))
CN103533947A (zh) 2010-12-28 2014-01-22 卡梅迪斯有限公司 用于治疗和预防感染的植物提取物
AU2011352207B2 (en) 2010-12-31 2016-03-03 Bioatla, Llc Comprehensive monoclonal antibody generation
US20120196294A1 (en) 2011-01-17 2012-08-02 Life Technologies Corporation Workflow for detection of ligands using nucleic acids
EP2665814B1 (fr) 2011-01-20 2017-05-17 Protalix Ltd. Construction d'acide nucléique pour l'expression d'une alpha-galactosidase chez des plantes et des cellules végétales
CN103476948A (zh) 2011-01-28 2013-12-25 领先细胞医疗诊断有限公司 用于测定头颈癌和宫颈病变中的hpv状态的rnascope* hpv测定法
US20130316358A1 (en) 2011-01-31 2013-11-28 Yeda Research And Development Co. Ltd. Methods of diagnosing disease using overlap extension pcr
US8658128B2 (en) 2011-02-03 2014-02-25 Pop Test Cortisol Llc System and method for diagnosis and treatment
CA2826467C (fr) 2011-02-07 2019-11-12 Research Development Foundation Polypeptides fc modifies d'immunoglobuline
WO2012116073A2 (fr) 2011-02-23 2012-08-30 The Board Of Trustees Of The University Of Illinois Dendron-hélices amphiphiles, micelles de ceux-ci et utilisations
US20130330349A1 (en) 2011-02-23 2013-12-12 Rappaport Family Institute For Research In The Medical Sciences High affinity molecules capable of binding a type a plexin receptor and uses of same
CN103597078B (zh) 2011-03-02 2016-12-14 富途锐基尼以色列有限公司 具有功能失调的t3ss蛋白的抗菌性转基因植物
EP2680864B1 (fr) 2011-03-03 2019-05-08 Ramot at Tel-Aviv University Ltd. Cellules musculaires génétiquement modifiées qui expriment des facteurs neurotrophiques
CN103597073B (zh) 2011-03-06 2019-06-07 默克雪兰诺有限公司 低岩藻糖细胞系及其应用
EP2683835B1 (fr) 2011-03-08 2017-01-11 King Abdullah University Of Science And Technology Biomarqueur moléculaire destiné à la détection précoce du cancer des ovaires
US9061006B2 (en) 2011-03-08 2015-06-23 Ramot At Tel-Aviv University Ltd. Compositions and methods for diagnosing and treating phenylketonuria (PKU)
US20140170068A1 (en) 2011-03-11 2014-06-19 Board Of Regents Of The University Of Nebraska Biomarker for coronary artery disease
WO2012123938A1 (fr) 2011-03-17 2012-09-20 Tel Hashomer Medical Research Infrastructure And Services Ltd. Analogues de quinolone pour le traitement de maladies auto-immunes
EP2686348B1 (fr) 2011-03-17 2015-12-30 Ramot at Tel-Aviv University Ltd. Anticorps asymétriques, bispécifiques et monospécifiques et procédés de génération de ceux-ci
JP2014511677A (ja) 2011-03-22 2014-05-19 コーネル・ユニバーシティー 鑑別困難な良性甲状腺病変と悪性甲状腺病変との識別法
KR101903339B1 (ko) 2011-03-22 2018-10-01 플루리스템 리미티드 방사선 또는 화학적 손상을 치료하는 방법
KR20140036164A (ko) 2011-03-24 2014-03-25 뉴림 파머슈티칼스 (1991) 리미티드 신경보호 펩타이드
WO2012131680A2 (fr) 2011-03-28 2012-10-04 Yeda Research And Development Co. Ltd. Compositions et procédés pour le traitement de l'inflammation
WO2012131594A1 (fr) 2011-03-28 2012-10-04 Novartis Ag Marqueurs associés aux inhibiteurs des kinases dépendantes des cyclines
ES2661466T3 (es) 2011-04-01 2018-04-02 Immunogen, Inc. Métodos para aumentar la eficacia de la terapia contra el cáncer con FOLR1
WO2012137202A1 (fr) 2011-04-05 2012-10-11 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Composition comprenant un indicateur de fer attaché à une microparticule et utilisations de celle-ci pour quantifier du fer non lié à la transferrine (ntbi) et du fer labile cellulaire (lci)
US9790262B2 (en) 2011-04-05 2017-10-17 Longevity Biotech, Inc. Compositions comprising glucagon analogs and methods of making and using the same
CA2832031C (fr) 2011-04-06 2019-09-17 Ramot At Tel-Aviv University Ltd. Procedes de controle et d'analyse du diagnostic de profils d'activite metabolique et utilisations therapeutiques desdits procedes
EP2694537A1 (fr) 2011-04-08 2014-02-12 Danisco US Inc. Compositions
WO2012142164A1 (fr) 2011-04-12 2012-10-18 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Anticorps monoclonaux humains qui se lient aux facteurs de croissance insulinomimétique (igf) de type i et ii
KR101910685B1 (ko) 2011-04-15 2018-10-22 플루리스템 리미티드 세포 수집 방법 및 시스템
MX383544B (es) 2011-04-21 2025-03-14 Univ Rockefeller Lisinas de bacteriofago de streptococcus para la deteccion y tratamiento de bacterias gram positivas
AU2012251353B2 (en) 2011-05-03 2016-10-27 Evogene Ltd. Isolated polynucleotides and polypeptides and methods of using same for increasing plant yield, biomass, growth rate, vigor, oil content, abiotic stress tolerance of plants and nitrogen use efficiency
US9192670B2 (en) 2011-05-04 2015-11-24 Ramot At Tel-Aviv University Ltd. Regulation of amyloid beta molecular composition for the treatment of alzheimer's disease
WO2012153333A1 (fr) 2011-05-09 2012-11-15 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Régénération et réparation de tissu mésenchymateux par utilisation d'amélogénine
WO2012153336A2 (fr) 2011-05-12 2012-11-15 Rakuto Bio Technologies Ltd. Procédés et dispositifs pour éclaircir la carnation de la peau
WO2012156976A1 (fr) 2011-05-16 2012-11-22 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Procédés de préparation d'artémisinine dans des plantes non-hôtes et vecteurs destinés à une utilisation dans celles-ci
WO2012162179A1 (fr) 2011-05-20 2012-11-29 Oligomerix, Inc. Compositions de protéase tau et procédés d'utilisation
CN107102135A (zh) 2011-05-20 2017-08-29 阿波特日本有限公司 用于减少非特异性结合的免疫检验方法和试剂
WO2012160526A2 (fr) 2011-05-23 2012-11-29 Ofir Menashe Formulations à base de particules contenant des micro-organismes et leurs utilisations
EP3263127B1 (fr) 2011-05-23 2019-08-21 Yeda Research and Development Co. Ltd Utilisation de la phosphorylation akt en tant que biomarqueur de pronostic de maladies neurodégénératives et le traitement de ceux-ci
KR102211724B1 (ko) 2011-05-31 2021-02-03 허치슨 바이오필름 메디컬 솔루션스 리미티드 세포 응집물의 분산 및 분리
HUE061244T2 (hu) 2011-05-31 2023-06-28 Biogen Ma Inc A PML kockázat értékelésének módszere
US20140113376A1 (en) 2011-06-01 2014-04-24 Rotem Sorek Compositions and methods for downregulating prokaryotic genes
US10166295B2 (en) 2011-06-02 2019-01-01 Opko Biologics Ltd. Pegylated OXM variants
ES2929575T3 (es) 2011-06-06 2022-11-30 Novo Nordisk As Anticuerpos terapéuticos
WO2012172555A1 (fr) 2011-06-14 2012-12-20 Yeda Research And Development Co. Ltd. Plurithérapie destinée à empêcher la formation de dcis et l'évolution en un cancer du sein
CA2838773A1 (fr) 2011-06-23 2012-12-27 Kaiima Bio Agritech Ltd. Ble commun, plantes ou parties de celles-ci ayant un genome partiellement ou completement multiplie, hybrides et produits de ceux-ci, et procedes de generation et d'utilisation
US9835621B2 (en) 2011-07-14 2017-12-05 University Of Kentucky Research Foundation Process for detection of alzheimer's disease from a serum sample
GB201112091D0 (en) 2011-07-14 2011-08-31 Gt Biolog Ltd Bacterial strains isolated from pigs
CA3149018A1 (fr) 2011-07-18 2013-01-24 President And Fellows Of Harvard College Molecules manipulees ciblant un microbe et leurs utilisations
KR20140062468A (ko) 2011-07-20 2014-05-23 카이마 바이오 아그리테크 리미티드 부분적으로 또는 완전히 다배수화된 게놈을 갖는 옥수수 식물체 및 이의 용도
EP2550982A1 (fr) 2011-07-27 2013-01-30 Technion Research & Development Foundation Ltd. Dispositifs pour applications chirurgicales
ES2632212T3 (es) 2011-08-04 2017-09-11 Yeda Research And Development Co. Ltd. miR-135 y composiciones que lo comprenden para el tratamiento de afecciones médicas asociadas con la serotonina
HUE039009T2 (hu) 2011-08-05 2018-12-28 Res Found Dev Javított eljárások és készítmények Olfml3-mediált angiogenesis modulálására
US9499793B2 (en) 2011-08-09 2016-11-22 Yeda Research And Development Co. Ltd. Downregulation of miR-7 for promotion of beta cell differentiation and insulin production
RU2014108930A (ru) 2011-08-14 2015-09-20 Каиима Био Агритех Лтд. Растения твердой пшеницы, обладающие частично или полностью умноженным геномом, и их применения
US9556281B2 (en) 2011-08-15 2017-01-31 The University Of Chicago Compositions and methods related to antibodies to staphylococcal protein A
WO2013025479A1 (fr) 2011-08-16 2013-02-21 Emory University Agents spécifiques de liaison à jaml, anticorps, et leurs utilisations associées
WO2013035070A1 (fr) 2011-09-07 2013-03-14 Yeda Research And Development Co. Ltd. Signature olfactive et mélange odorant la contenant
SG11201400513PA (en) 2011-09-08 2014-06-27 Yeda Res & Dev Anti third party central memory t cells, methods of producing same and use of same in transplantation and disease treatment
ES2657552T3 (es) 2011-09-08 2018-03-05 Yeda Research And Development Co. Ltd. Nuevos biomarcadores de riesgo para el cáncer de pulmón
BR112014005975A8 (pt) 2011-09-13 2017-09-12 Monsanto Technology Llc Método de controle de planta, método de redução de expressão de um gene pds em uma planta, cassete de expressão microbiana, método de fazer um polinucleotídeo, método de identificação de polinucleotídeos, e composições para controle de erva daninha
CA2848685A1 (fr) 2011-09-13 2013-03-21 Monsanto Technology Llc Methodes et compositions de controle des mauvaises herbes comprenant l'application topique de polynucleotide de glutamine synthetase
EP3434780A1 (fr) 2011-09-13 2019-01-30 Monsanto Technology LLC Procédés et compositions de lutte contre les mauvaises herbes
BR112014005958A2 (pt) 2011-09-13 2020-10-13 Monsanto Technology Llc métodos e composições químicas agrícolas para controle de planta, método de redução de expressão de um gene accase em uma planta, cassete de expressão microbiana, método para fazer um polinucleotídeo, método de identificação de polinucleotídeos úteis na modulação de expressão do gene accase e composição herbicida
US9840715B1 (en) 2011-09-13 2017-12-12 Monsanto Technology Llc Methods and compositions for delaying senescence and improving disease tolerance and yield in plants
US10829828B2 (en) 2011-09-13 2020-11-10 Monsanto Technology Llc Methods and compositions for weed control
US10760086B2 (en) 2011-09-13 2020-09-01 Monsanto Technology Llc Methods and compositions for weed control
US10806146B2 (en) 2011-09-13 2020-10-20 Monsanto Technology Llc Methods and compositions for weed control
US9920326B1 (en) 2011-09-14 2018-03-20 Monsanto Technology Llc Methods and compositions for increasing invertase activity in plants
US9249467B2 (en) 2011-09-16 2016-02-02 Steven Goodison Bladder cancer detection composition, kit and associated methods
CA2851270C (fr) 2011-10-05 2023-03-14 The Rockefeller University Lysines bacteriophages dimeres
GB201117313D0 (en) 2011-10-07 2011-11-16 Gt Biolog Ltd Bacterium for use in medicine
WO2013054320A1 (fr) 2011-10-11 2013-04-18 Tel Hashomer Medical Research Infrastructure And Services Ltd. Anticorps dirigés contre la molécule d'adhésion cellulaire associée à l'antigène carcino-embryonnaire (ceacam)
CN104011068A (zh) 2011-10-21 2014-08-27 奥古雷克斯生命科学公司 衍生自瓜氨酸化的14-3-3的抗原及其在风湿性关节炎诊断中的用途
US9145559B2 (en) 2011-10-27 2015-09-29 Yeda Research And Development Co. Ltd. Methods of treating cancer
WO2013064163A1 (fr) 2011-11-01 2013-05-10 Academisch Medisch Centrum Marqueurs de méthylation pour le cancer colorectal
EP2773758B1 (fr) 2011-11-03 2017-06-07 Quark Pharmaceuticals, Inc. Compositions pour la neuroprotection
US20140323549A1 (en) 2011-11-08 2014-10-30 Quark Pharmaceuticals, Inc. Methods and compositions for treating diseases, disorders or injury of the nervous system
WO2013076729A1 (fr) 2011-11-23 2013-05-30 Danziger Dan Flower Farm Plantes de type otomeria
WO2013076730A1 (fr) 2011-11-27 2013-05-30 Yeda Research And Development Co. Ltd. Méthodes de régulation de l'angiogenèse et compositions capables de réguler l'angiogenèse
WO2013084190A1 (fr) 2011-12-08 2013-06-13 Yeda Research And Development Co. Ltd. Cellules pulmonaires fœtales de mammifères et leur utilisation thérapeutique
EP2795295B1 (fr) 2011-12-12 2017-10-11 Step Ahead Innovations, Inc. Systèmes de surveillance de la qualité d´eau
WO2013093921A1 (fr) 2011-12-20 2013-06-27 Collplant Ltd. Fibres de polymère synthétique enrobées de collagène
WO2013095729A1 (fr) 2011-12-22 2013-06-27 Life Technologies Corporation Dispositif capillaire à écoulement latéral séquentiel pour la détermination d'un analyte
RU2657758C2 (ru) 2011-12-22 2018-06-15 Иеда Рисеч Энд Девелопмент Ко. Лтд. Комбинированная терапия для стабильного и долговременного приживления трансплантата
US9035039B2 (en) 2011-12-22 2015-05-19 Protiva Biotherapeutics, Inc. Compositions and methods for silencing SMAD4
CN104270939A (zh) 2011-12-28 2015-01-07 凯伊玛生物农业科技有限公司 具有部分加倍或完全加倍的基因组的栽培高粱植物及其应用
WO2013101758A1 (fr) 2011-12-29 2013-07-04 Baylor Research Institute Biomarqueurs de la maladie de kawasaki
WO2013098813A1 (fr) 2012-01-01 2013-07-04 Qbi Enterprises Ltd. Particules ciblant endo180 pour l'administration sélective d'agents thérapeutiques et diagnostiques
EP2807271B1 (fr) 2012-01-24 2018-08-22 CD Diagnostics, Inc. Système de détection d'une infection dans le liquide synovial
WO2013114363A2 (fr) 2012-01-30 2013-08-08 Yeda Research And Development Co.Ltd. Agents antimicrobiens
WO2013114371A1 (fr) 2012-02-01 2013-08-08 Protalix Ltd. Formulation en poudre sèche de dnase i
US10184131B2 (en) 2012-02-06 2019-01-22 A.B. Seeds Ltd. Isolated polynucleotides expressing or modulating microRNAs or targets of same, transgenic plants comprising same and uses thereof
WO2013121426A1 (fr) 2012-02-13 2013-08-22 Gamida-Cell Ltd. Culture de cellules souches mésenchymateuses
PE20142290A1 (es) 2012-02-14 2015-01-15 Opko Biolog Ltd Factores de coagulacion de accion prolongada y metodos de produccion de los mismos
IN2014MN01806A (fr) 2012-02-19 2015-07-03 Protalix Ltd
WO2013124816A2 (fr) 2012-02-22 2013-08-29 Brainstem Biotec Ltd. Génération de cellules souches neuronales et de motoneurones
EP2844744A2 (fr) 2012-02-22 2015-03-11 Brainstem Biotec Ltd. MicroARN POUR LA GÉNÉRATION D'ASTROCYTES
US9352042B2 (en) 2012-02-24 2016-05-31 Protiva Biotherapeutics, Inc. Trialkyl cationic lipids and methods of use thereof
DK2820006T3 (da) 2012-02-29 2017-11-06 Chemocentryx Inc Pyrazol-1-yl benzen sulfonamider som ccr9 antagonister
EP2833714A1 (fr) 2012-03-01 2015-02-11 The State of Israel - Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Center) Plantes d'ail stérile mâle, descendance hybride de celles-ci et procédés de génération et d'utilisation de celles-ci
WO2013132495A1 (fr) 2012-03-07 2013-09-12 Yeda Research And Development Co. Ltd. Compositions inhibitrices de la quiescine sulfhydryle oxydase (qsox1) et leurs utilisations
EP3575311A1 (fr) 2012-03-20 2019-12-04 Biogen MA Inc. Anticorps neutralisant le virus jcv
US9334308B2 (en) 2012-03-22 2016-05-10 Ramot At Tel-Aviv University Ltd. PLIF multimeric peptides and uses thereof
HK1206610A1 (en) 2012-03-30 2016-01-15 Sorrento Therapeutics, Inc. Fully human antibodies that bind to vegfr2
US20140178869A1 (en) 2012-04-05 2014-06-26 Advanced Cell Diagnostics, Inc. Detection of immunoglobulin light chain restriction by rna in situ hybridization
WO2013156989A1 (fr) 2012-04-18 2013-10-24 Ramot At Tel-Aviv University Ltd. Particules de glycosaminoglycane lipidé pour la libération d'acides nucléiques
WO2013157002A1 (fr) 2012-04-19 2013-10-24 Prolor Biotech Inc. Variants d'oxyntomoduline à action prolongée et procédés pour les produire
US20130280696A1 (en) 2012-04-23 2013-10-24 Elliott Millenson Devices and methods for detecting analyte in bodily fluid
WO2013160895A1 (fr) 2012-04-24 2013-10-31 Biokine Therapeutics Ltd. Peptides et leur utilisation dans le traitement du cancer du poumon à grandes cellules
AU2013252888B2 (en) 2012-04-26 2018-06-14 University Of Chicago Compositions and methods related to antibodies that neutralize coagulase activity during Staphylococcus aureus disease
EP2846819B1 (fr) 2012-05-09 2017-05-03 Yeda Research and Development Co. Ltd. Variants de pro-domaine tace en tant qu'inhibiteur de tnf-a et leur utilisation médicale
EP3553089A1 (fr) 2012-05-10 2019-10-16 Bioatla, LLC Anticorps monoclonaux multispécifiques
US8865158B2 (en) 2012-05-22 2014-10-21 Ramot At Tel-Aviv University Ltd. Bacteriophages for reducing toxicity of bacteria
SG11201408330XA (en) 2012-05-24 2015-01-29 Mountgate Group Ltd Compositions and methods related to prevention and treatment of rabies infection
CN104619843B (zh) 2012-05-24 2020-03-06 A.B.种子有限公司 用于使基因表达沉默的组合物和方法
US9175082B2 (en) 2012-05-31 2015-11-03 Sorrento Therapeutics, Inc. Antigen binding proteins that bind PD-L1
ES2786128T3 (es) 2012-06-01 2020-10-08 Icahn School Med Mount Sinai Niveles de ceramida en el tratamiento y prevención de infecciones
WO2013183048A1 (fr) 2012-06-03 2013-12-12 Ben-Gurion University Of The Negev Research And Development Authority Peptides de liaison au titane fonctionnalisés et implants revêtus par ceux-ci
MX362432B (es) 2012-06-04 2019-01-17 Opko Biologics Ltd Variantes de oxm pegilada.
HK1208181A1 (en) 2012-06-21 2016-02-26 Sorrento Therapeutics, Inc. Antigen binding proteins that bind c-met
JP6366580B2 (ja) 2012-06-22 2018-08-01 エイチティージー モレキュラー ダイアグノスティクス， インコーポレイテッド メラニン細胞性病変における分子悪性度
CN105051065A (zh) 2012-06-22 2015-11-11 索伦托治疗有限公司 与ccr2结合的抗原结合蛋白
WO2014006621A1 (fr) 2012-07-03 2014-01-09 Nanospun Technologies Ltd. Procédés et dispositifs pour l'adsorption et la biodégradation de pétrole
ES2776365T3 (es) 2012-07-09 2020-07-30 Novartis Ag Biomarcadores asociados con inhibidores de CDK
EP2872619B1 (fr) 2012-07-11 2018-02-14 Imstem Biotechnology Inc. Cellules souches de type mésenchymateuses issues de cellules souches embryonnaires humaines, leurs procédés et leurs utilisations
EP2875078B1 (fr) 2012-07-18 2017-12-20 President and Fellows of Harvard College Modification de surfaces pour une répulsion et une liaison ciblée simultanées de fractions désirées
WO2014018375A1 (fr) 2012-07-23 2014-01-30 Xenon Pharmaceuticals Inc. Cyp8b1 et ses utilisations dans des méthodes thérapeutiques et diagnostiques
US9175266B2 (en) 2012-07-23 2015-11-03 Gamida Cell Ltd. Enhancement of natural killer (NK) cell proliferation and activity
US9567569B2 (en) 2012-07-23 2017-02-14 Gamida Cell Ltd. Methods of culturing and expanding mesenchymal stem cells
NZ741124A (en) 2012-07-27 2019-11-29 Univ Illinois Engineering t-cell receptors
ES2730377T3 (es) 2012-07-29 2019-11-11 Yeda Res & Dev Uso de la ruta reductora de la glicina para generar microorganismos formatótrofos y autótrofos
WO2014020502A2 (fr) 2012-07-31 2014-02-06 Novartis Ag Marqueurs associés à des inhibiteurs de double minute 2 humains
JP6340366B2 (ja) 2012-07-31 2018-06-06 イェダ リサーチ アンド デベロップメント カンパニー リミテッド 運動ニューロン疾患を診断および処置する方法
EP2880151B1 (fr) 2012-08-06 2020-06-03 Brainstorm Cell Therapeutics Ltd. Procédés de génération de cellules souches mésechymateuses qui sécrètent des facteurs neurotrophiques
TR201900694T4 (tr) 2012-08-23 2019-02-21 Agensys Inc 158p1d7 proteinlerine bağlanan antikor ilaç konjugatları (adc).
WO2014033723A1 (fr) 2012-09-03 2014-03-06 A.B. Seeds Ltd. Procédé d'amélioration de la tolérance au stress abiotique des plantes et plantes ainsi produites
WO2014041544A1 (fr) 2012-09-12 2014-03-20 Ramot At Tel-Aviv University Ltd. Immunoparticules et procédés pour les produire et les utiliser
EP3677310A1 (fr) 2012-10-08 2020-07-08 St. Jude Children's Research Hospital Thérapies fondées sur la régulation de la stabilité et de la fonction des lymphocytes t régulateurs par l'intermédiaire d'un axe neuropiline-1:sémaphorine
WO2014057490A1 (fr) 2012-10-09 2014-04-17 Ramot At Tel-Aviv University Ltd. Procédés et trousses utilisant la mortaline soluble dans le sang pour prédire un pronostic de cancer
EP2906596B1 (fr) 2012-10-12 2023-12-27 Arizona Board of Regents on behalf of Arizona State University Réactifs à base d'anticorps qui reconnaissent spécifiquement des formes oligomériques toxiques de tau
BR112015008706A2 (pt) 2012-10-18 2018-02-06 Monsanto Technology Llc métodos e composições para controle de praga de plantas
WO2014063097A1 (fr) 2012-10-19 2014-04-24 Danisco Us Inc. Stabilisation de membranes biomimétiques
US20150354006A1 (en) 2012-10-19 2015-12-10 Novartis Ag Markers for acute lymphoblastic leukemia
US9395369B2 (en) 2012-10-19 2016-07-19 Regents Of The University Of Minnesota Guinea pig cytomegalovirus (CIDMTR strain)
CN104918639B (zh) 2012-10-22 2018-01-26 萨拜格Rfa公司 用于将治疗剂递送到活细胞和细胞核中的系统
CA2888345C (fr) 2012-10-24 2020-04-21 Research Development Foundation Anticorps anti-jam-c et procedes pour le traitement du cancer
WO2014064682A1 (fr) 2012-10-24 2014-05-01 Yeda Research And Development Co. Ltd. Combinaisons d'anticorps ciblant les récepteurs du facteur de croissance épidermique pour traiter le cancer
WO2014068553A1 (fr) 2012-10-29 2014-05-08 Yeda Research And Development Co. Ltd. Aptamères, aptamères multimères et leurs utilisations
SG11201503879QA (en) 2012-11-20 2015-06-29 Opko Biolog Ltd Method of increasing the hydrodynamic volume of polypeptides by attaching to gonadotrophin carboxy terminal peptides
MX2015004626A (es) 2012-11-29 2015-07-14 Yeda Res & Dev Metodos para prevenir metastasis de tumor, tratar y pronosticar cancer e identificar agentes que son inhibidores putativos de metastasis.
UY35251A (es) 2013-01-01 2014-07-31 Seeds Ltd Ab MOLÉCULAS DE dsRNA AISLADAS Y MÉTODOS PARA USARLAS PARA SILENCIAR MOLÉCULAS DIANA DE INTERÉS
US10683505B2 (en) 2013-01-01 2020-06-16 Monsanto Technology Llc Methods of introducing dsRNA to plant seeds for modulating gene expression
US10047399B2 (en) 2013-01-07 2018-08-14 The Cleveland Clinic Foundation ABCA1 downregulation in prostate cancer
WO2014108850A2 (fr) 2013-01-09 2014-07-17 Yeda Research And Development Co. Ltd. Analyse de transcriptome à haut débit
WO2014108854A1 (fr) 2013-01-09 2014-07-17 Fusimab Ltd. Anticorps anti-hgf et anti-ang2 monospécifiques, et anticorps anti-hgf/anti-ang2 bispécifiques
ES2681425T3 (es) 2013-01-17 2018-09-13 Novellusdx Ltd. Métodos y sistemas para la identificación de mutaciones conductoras específicas
WO2014116721A1 (fr) 2013-01-22 2014-07-31 The Arizona Board Of Regents For And On Behalf Of Arizona State University Vecteur geminiviral pour l'expression du rituximab
US10000767B2 (en) 2013-01-28 2018-06-19 Monsanto Technology Llc Methods and compositions for plant pest control
US9411930B2 (en) 2013-02-01 2016-08-09 The Regents Of The University Of California Methods for genome assembly and haplotype phasing
CN108624668B (zh) 2013-02-01 2022-12-02 加利福尼亚大学董事会 用于基因组组装及单体型定相的方法
DK2951290T3 (en) 2013-02-01 2018-01-22 Us Health PROCEDURE FOR PREPARING RETINAL PIGMENTAL EPIT (RPE) CELLS FROM INDUCED PLURIPOTENT STEM CELLS (IPSCS)
EP2950808B1 (fr) 2013-02-04 2019-08-21 Ramot at Tel-Aviv University Ltd. Génération de lignées cellulaires spécifiques d'une tumeur cytotoxiques et leurs utilisations
WO2014130846A1 (fr) 2013-02-22 2014-08-28 Seungpyo Hong Administration d'un médicament par voie transdermique faisant appel à des micelles amphiphiles « dendron-coil »
AU2014224174B2 (en) 2013-03-06 2018-08-30 Hadasit Medical Research Services And Development Ltd. Use of plant cells expressing a TNFalpha polypeptide inhibitor in therapy
EP2964668B1 (fr) 2013-03-06 2019-11-27 Protalix Ltd. Polypeptides inhibiteurs de tnf alpha, polynucléotides codant pour ceux-ci, cellules exprimant ceux-ci et leurs procédés de production
TWI582239B (zh) 2013-03-11 2017-05-11 諾華公司 與ｗｎｔ抑制劑相關之標記
AU2014248958A1 (en) 2013-03-13 2015-10-01 Monsanto Technology Llc Methods and compositions for weed control
CA2905027A1 (fr) 2013-03-13 2014-10-09 Monsanto Technology Llc Procedes et compositions utilisables pour lutter contre les mauvaises herbes
WO2014159239A2 (fr) 2013-03-14 2014-10-02 Novartis Ag Anticorps dirigés contre notch 3
US20140283211A1 (en) 2013-03-14 2014-09-18 Monsanto Technology Llc Methods and Compositions for Plant Pest Control
US9273349B2 (en) 2013-03-14 2016-03-01 Affymetrix, Inc. Detection of nucleic acids
WO2014159242A1 (fr) 2013-03-14 2014-10-02 Novartis Ag Mutants de notch 3 et leurs utilisations
WO2014153056A2 (fr) 2013-03-14 2014-09-25 Parkash Gill Traitement anticancéreux à l'aide d'anticorps qui se lient à grp78 de surface cellulaire
US20140273031A1 (en) 2013-03-15 2014-09-18 The Cleveland Clinic Foundation In-vitro method for monoclonal antibody production
ES2935257T3 (es) 2013-03-15 2023-03-03 Univ Chicago Métodos y composiciones relacionadas con la actividad de las células T
PT3524618T (pt) 2013-03-15 2023-06-06 Gladiator Biosciences Inc Domínios gla como agentes de marcação
WO2014145718A2 (fr) 2013-03-15 2014-09-18 Longevity Biotech, Inc. Peptides comprenant des acides aminés non endogènes et procédés de fabrication et d'utilisation associés
US10568328B2 (en) 2013-03-15 2020-02-25 Monsanto Technology Llc Methods and compositions for weed control
CN105263511A (zh) 2013-03-21 2016-01-20 科尔普兰特有限公司 用于组织再生的包含胶原和prp的组合物
JP6346265B2 (ja) 2013-03-21 2018-06-20 ジェニスフィア・エルエルシー Ｄｎａインターカレーティング剤の細胞送達
CN105163749B (zh) 2013-03-24 2018-03-27 拜欧肯治疗有限公司 治疗骨髓性白血病的方法
KR20240122922A (ko) 2013-03-27 2024-08-13 세다르스-신나이 메디칼 센터 Tl1a 기능 및 관련된 신호전달 경로의 저해에 의한 섬유증 및 염증의 완화 및 반전
GB201306536D0 (en) 2013-04-10 2013-05-22 Gt Biolog Ltd Polypeptide and immune modulation
BR112015026702A2 (pt) 2013-04-21 2018-02-06 Yeda Res And Developmente Co Ltd métodos de extermínio de células senescentes
CN105531365A (zh) 2013-04-23 2016-04-27 耶达研究及发展有限公司 分离的幼稚多能干细胞和产生所述细胞的方法
EP2989119B1 (fr) 2013-04-25 2018-03-21 Yeda Research and Development Co., Ltd. Utilisation de peptides inhibiteurs pour le traitement de maladies inflammatoires
WO2014176047A1 (fr) 2013-04-25 2014-10-30 Novartis Ag Marqueurs pour des inhibiteurs de l'ezh2
EP2999717B1 (fr) 2013-05-21 2018-08-08 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Traitement des pathologies impliquant des mastocytes
EP3848045A1 (fr) 2013-05-21 2021-07-14 President and Fellows of Harvard College Compositions se liant à l'hème manipulées et leurs utilisations
BR112015029815B1 (pt) 2013-05-27 2020-06-30 Rakuto Bio Technologies Ltd Composição cosmética para clarear uma pele e/ou cabelo de um indiví$#205;duo e conjunto para clarear uma pele e/ou cabelo de um indivíduo
EP3004334A4 (fr) 2013-05-28 2016-12-21 Biogen Ma Inc Méthodes d'évaluation de risque de développement d'une lemp
JP6600302B2 (ja) 2013-06-12 2019-10-30 ザ ジェネラル ホスピタル コーポレイション 標的分子のマルチプレックス検出のための方法、キット、およびシステム、ならびにそれらの使用
KR20160054456A (ko) 2013-06-18 2016-05-16 디엔에이트릭스, 인코포레이티드 종양용해성 아데노바이러스를 사용한 뇌암의 치료
WO2014205230A1 (fr) 2013-06-19 2014-12-24 Step Ahead Innovations Inc. Systèmes et procédés de test de paramètres relatifs à l'eau dans un environnement aquatique
WO2014207744A1 (fr) 2013-06-24 2014-12-31 Ramot At Tel-Aviv University Ltd. Échafaudage à base d'épiploon et système d'administration
WO2014210540A1 (fr) 2013-06-28 2014-12-31 Baylor Research Institute Immunothérapie par ciblage d'asgpr de cellules dendritiques pour la sclérose en plaques
MX359191B (es) 2013-07-19 2018-09-18 Monsanto Technology Llc Composiciones y métodos para controlar leptinotarsa.
EP3022295A4 (fr) 2013-07-19 2017-03-01 Cedars-Sinai Medical Center Signature de la voie de signalisation de tl1a (tnfsf15)
US9850496B2 (en) 2013-07-19 2017-12-26 Monsanto Technology Llc Compositions and methods for controlling Leptinotarsa
WO2015015489A1 (fr) 2013-07-30 2015-02-05 Biolinerx Ltd. Anticorps convenant au traitement du diabète et de maladies autoimmunes
AR097161A1 (es) 2013-08-01 2016-02-24 Agensys Inc Conjugados de fármacos anticuerpo (adc) que se unen a las proteínas cd37
WO2015027120A1 (fr) 2013-08-21 2015-02-26 Jiang Jean X Compositions et méthodes de ciblage de semi-canaux de connexine
ES2702674T3 (es) 2013-08-29 2019-03-04 Yeda Res & Dev Inhibidores selectivos de la isoforma alfa2 de Na,K-ATPasa y el uso para la reducción de la presión intraocular
NZ717140A (en) 2013-08-30 2022-05-27 Immunogen Inc Antibodies and assays for detection of folate receptor 1
IL228284A (en) 2013-09-03 2016-12-29 Technion Res & Dev Foundation Implants from cellular scaffolding and blood vessel stalk
US20160251410A1 (en) 2013-09-03 2016-09-01 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Compositions and methods for expressing recombinant polypeptides
WO2015033344A1 (fr) 2013-09-05 2015-03-12 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Procédés et nécessaires permettant d'inhiber la pathogénicité d'un streptocoque du groupe a (sga) ou d'un streptocoque du groupe g (sgg)
WO2015037009A1 (fr) 2013-09-16 2015-03-19 Plexicure Ltd. Protéines isolées capables de se lier à la plexine-a4, et procédés de production et d'utilisation
EP3046929B1 (fr) 2013-09-17 2019-01-16 Yeda Research and Development Co., Ltd. Nouveaux peptides d'erk et leurs utilisations
US20160237404A1 (en) 2013-10-01 2016-08-18 Kadimastem Ltd. Directed differentiation of astrocytes from human pluripotent stem cells for use in drug screening and the treatment of amyotrophic laterial sclerosis (als)
EP3052193B1 (fr) 2013-10-03 2018-01-31 Oklahoma Medical Research Foundation Biomarqueurs d'activité, de l'intensité et de l'éruption de la maladie du lupus érythémateux disséminé
US9476884B2 (en) 2013-10-04 2016-10-25 University Of Massachusetts Hybridization- independent labeling of repetitive DNA sequence in human chromosomes
WO2015052717A1 (fr) 2013-10-07 2015-04-16 Yeda Research And Development Co. Ltd. Dispositif microfluidique pour analyser l'expression de gènes
HUE050002T2 (hu) 2013-10-21 2020-11-30 Opko Biologics Ltd Hosszan ható polipeptidek és eljárás azok elõállítására és beadására
US20150158926A1 (en) 2013-10-21 2015-06-11 Opko Biologics, Ltd. Long-acting polypeptides and methods of producing and administering same
US10767156B2 (en) 2013-10-24 2020-09-08 Yeda Research And Development Co., Ltd. Polynucleotides encoding BREX system polypeptides and methods of using same
EP3062809B1 (fr) 2013-10-31 2020-07-08 Biokine Therapeutics Ltd. Un inhibiteur peptidique de cxcr4 pour le traitement de la leucémie myéloïde aiguë avec mutation de la flt3
AR098295A1 (es) 2013-11-04 2016-05-26 Monsanto Technology Llc Composiciones y métodos para controlar infestaciones de plagas y parásitos de los artrópodos
US20170002064A1 (en) 2013-11-08 2017-01-05 The Board Of Regents Of The University Of Texas System Vh4 antibodies against gray matter neuron and astrocyte
WO2015073707A1 (fr) 2013-11-15 2015-05-21 The Board Of Trustees Of The Leland Stanford Junior University Procédés de traitement d'une insuffisance cardiaque avec des agonistes de récepteur 2 d'hypocrétine
ES2874704T3 (es) 2013-11-20 2021-11-05 Univ Iowa Res Found Procedimiento para monitorizar la eficacia de un tratamiento de la enfermedad de Alzheimer con una isoforma de ApoE
JP6476182B2 (ja) 2013-11-22 2019-02-27 ザ ボード オブ トラスティーズ オブ ザ ユニバーシティ オブ イリノイ 改変された高親和性ヒトｔ細胞受容体
EP3074044A2 (fr) 2013-11-28 2016-10-05 Yeda Research and Development Co., Ltd. Inhibiteurs de synaptojanine-2 et leurs utilisations
EP3074391B1 (fr) 2013-11-28 2019-07-31 Tel Hashomer Medical Research Infrastructure And Services Ltd. Inhibiteurs de l'arn polymérase i et leurs utilisations
US10053712B2 (en) 2013-12-10 2018-08-21 Yeda Research And Development Co. Ltd. Use of enzymes which catalyze pyruvate synthesis from formate and acetyl-CoA and bacteria expressing same
UA119253C2 (uk) 2013-12-10 2019-05-27 Біолоджикс, Інк. Спосіб боротьби із вірусом у кліща varroa та у бджіл
US20150191744A1 (en) 2013-12-17 2015-07-09 University Of Massachusetts Cas9 effector-mediated regulation of transcription, differentiation and gene editing/labeling
US10513546B2 (en) 2013-12-18 2019-12-24 President And Fellows Of Harvard College CRP capture/detection of gram positive bacteria
DK3083936T3 (en) 2013-12-19 2018-10-22 Danisco Us Inc USE OF HYDROPHOBINES TO INCREASE GAS TRANSFER IN AEROBE FERMENTATION PROCESSES
ES2819865T3 (es) 2014-01-07 2021-04-19 Bioatla Llc Proteínas dirigidas a ortólogos
WO2015106281A1 (fr) 2014-01-13 2015-07-16 Baylor Research Institute Nouveaux vaccins contre le vph et maladies liées au vph
AU2015206585A1 (en) 2014-01-15 2016-07-21 Monsanto Technology Llc Methods and compositions for weed control using EPSPS polynucleotides
CN106132992B (zh) 2014-01-29 2020-08-07 达娜-法勃肿瘤研究所公司 针对muc1-c/胞外结构域(muc1-c/ecd)的抗体
WO2015114633A1 (fr) 2014-01-30 2015-08-06 Yissum Research And Development Company Of The Hebrew University Of Jerusalem Ltd. Peptides se liant à l'actine et compositions les contenant pour inhiber l'angiogenèse et traiter des affections médicales associées à celle-ci
JP2017506259A (ja) 2014-02-03 2017-03-02 イッスム・リサーチ・ディベロップメント・カンパニー・オブ・ザ・ヘブルー・ユニバーシティ・オブ・エルサレム・リミテッドＹｉｓｓｕｍ Ｒｅｓｅａｒｃｈ Ｄｅｖｅｌｏｐｍｅｎｔ Ｃｏｍｐａｎｙ Ｏｆ Ｔｈｅ Ｈｅｂｒｅｗ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｊｅｒｕｓａｌｅｍ Ｌｔｄ． 幹細胞を枯渇させるためのカゼインキナーゼｉ阻害剤の使用
US10125365B2 (en) 2014-02-05 2018-11-13 Yeda Research And Development Co. Ltd. Micro-RNAs and compositions comprising same for the treatment and diagnosis of serotonin-, adrenalin-, noradrenalin-, glutamate-, and corticotropin-releasing hormone- associated medical conditions
CN106573976B (zh) 2014-02-06 2020-05-05 耶达研究及发展有限公司 抗cd84抗体、包含所述抗体的组合物及其用途
US20150247204A1 (en) 2014-02-07 2015-09-03 The General Hopital Corporation Differential diagnosis of hepatic neoplasms
US20170101633A1 (en) 2014-02-10 2017-04-13 Protalix Ltd. Method of maintaining disease stability in a subject having gaucher's disease
EP3105587B1 (fr) 2014-02-11 2023-09-06 Brainstorm Cell Therapeutics Ltd. Procédé de qualification de cellules
US20150232935A1 (en) 2014-02-14 2015-08-20 The General Hospital Corporation Methods for diagnosing igg4-related disease
US20150247205A1 (en) 2014-02-28 2015-09-03 The General Hospital Corporation Diagnosis of multiple myeloma and lymphoma
CN106255882A (zh) 2014-03-03 2016-12-21 耶路撒冷希伯来大学伊森姆研究发展公司 用于检测铜绿假单胞菌的方法和装置
EP2923709A1 (fr) 2014-03-28 2015-09-30 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Vaccin contre la malaria multi-composants-multi-étapes
EP3420809A1 (fr) 2014-04-01 2019-01-02 Monsanto Technology LLC Compositions et procédés pour lutter contre les insectes nuisibles
CA2945438C (fr) 2014-04-10 2023-08-22 Bonus Therapeutics Ltd. Compositions pour la reparation des os
SI4026917T1 (sl) 2014-04-14 2024-05-31 Yissum Research And Development Company Of The Hebrew University Of Jerusalem Ltd. Metoda in komplet za določanje smrti celic ali tkiva oz. izvora DNK tkiva ali celice z analizo metilacije DNK
EP3132057B1 (fr) 2014-04-17 2019-10-16 Yeda Research and Development Co. Ltd. Procédés et kits pour analyser les fragments se liant à l'adn liés à l'adn
JP6805428B2 (ja) 2014-04-27 2021-01-06 フェイムウェイヴ リミテッド Ｃｅａｃａｍ１に対するヒト化抗体
US11427647B2 (en) 2014-04-27 2022-08-30 Famewave Ltd. Polynucleotides encoding humanized antibodies against CEACAM1
WO2015166492A2 (fr) 2014-04-28 2015-11-05 Yeda Research And Development Co. Ltd. Réponse du microbiome à des agents
MX2016014128A (es) 2014-05-04 2017-05-23 Forrest Innovations Ltd Composiciones y procedimientos para recudir el enverdecimiento de los citricos inducido por patogenos.
EP2942627A1 (fr) 2014-05-05 2015-11-11 MicroBPlex, Inc. MILIEUX PRÉPARÉS AVEC DES ANTICORPS NOUVELLEMENT SYNTHÉTISÉS (MENSA) PAR DES CELLULES SéCRéTANT DES ANTICORPS RéCEMMENT PROLIFEéRéES ET LEURS UTILISATIONS
AU2015255883A1 (en) 2014-05-08 2016-10-27 Novodiax, Inc. Direct immunohistochemistry assay
WO2015179435A1 (fr) 2014-05-19 2015-11-26 Bayer Healthcare Llc Anticorps monoclonaux humanisés optimisés dirigés contre la protéine c activée et leurs utilisations
EP3145947B1 (fr) 2014-05-22 2025-02-12 Yeda Research and Development Co., Ltd. Micro-organismes recombinés pouvant fixer le carbone
US20170253881A1 (en) 2014-06-02 2017-09-07 Technion Research & Development Foundation Limited Compositions and methods of selectively inhibiting irp1 and treating inflammation
EP3149155B1 (fr) 2014-06-02 2020-09-23 Kadimastem Ltd. Procédés d'induction de la myélinisation et de maturation des oligodendrocytes
US10988764B2 (en) 2014-06-23 2021-04-27 Monsanto Technology Llc Compositions and methods for regulating gene expression via RNA interference
WO2015198320A1 (fr) 2014-06-24 2015-12-30 Insight Biopharmaceuticals Ltd. Procédés de purification d'anticorps
EP3161138A4 (fr) 2014-06-25 2017-12-06 Monsanto Technology LLC Procédés et compositions pour administrer des acides nucléiques à des cellules végétales et réguler l'expression génique
KR20170041192A (ko) 2014-06-25 2017-04-14 텔 하쇼머 메디컬 리서치 인프라스트럭쳐 앤드 서비시스 리미티드． 암 줄기세포 마커의 동정 및 진단 및 치료를 위한 그의 사용
JP2017520549A (ja) 2014-06-26 2017-07-27 ラモット アット テル アビブ ユニバーシティ， リミテッド 核酸の送達のためのリポソーム製剤
WO2016005985A2 (fr) 2014-07-09 2016-01-14 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Méthode pour reprogrammer des cellules
HUE049261T2 (hu) 2014-07-15 2020-09-28 Yissum Research And Development Company Of The Hebrew Univ Of Jerusalem Ltd CD44 izolált polipeptidek és alkalmazásaik
US11015229B2 (en) 2014-07-21 2021-05-25 Novellusdx Ltd. Methods and systems for determining oncogenic index of patient specific mutations
CA2955411A1 (fr) 2014-07-21 2016-01-28 Novellusdx Ltd. Procedes de determination d'une reponse a un medicament de mutations specifiques a un patient
CN114009454A (zh) 2014-07-29 2022-02-08 孟山都技术公司 用于控制昆虫害虫的组合物和方法
CN122465832A (zh) 2014-07-30 2026-07-28 耶达研究及发展有限公司 用于培养多能干细胞的培养基
AU2015296029B2 (en) 2014-08-01 2022-01-27 Dovetail Genomics, Llc Tagging nucleic acids for sequence assembly
RU2730836C2 (ru) 2014-08-14 2020-08-26 Мемед Диагностикс Лтд. Вычислительный анализ биологических данных с применением многообразия и гиперплоскости
SG11201701382PA (en) 2014-08-22 2017-03-30 Sorrento Therapeutics Inc Antigen binding proteins that bind cxcr3
WO2016030899A1 (fr) 2014-08-28 2016-03-03 Yeda Research And Development Co. Ltd. Méthodes de traitement de la sclérose latérale amyotrophique
WO2016038610A1 (fr) 2014-09-08 2016-03-17 Yeda Research And Development Co. Ltd. Compositions et procédés de traitement d'un cancer résistant à un inhibiteur de la tyrosine kinase (tki)
US10526416B2 (en) 2014-09-08 2020-01-07 Yeda Research And Development Co. Ltd. Anti-HER3 antibodies and uses of same
EP2992895A1 (fr) 2014-09-08 2016-03-09 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Vaccin contre la malaria multi-composants-multi-étapes
IL287789B2 (en) 2014-09-11 2024-05-01 The State Of Israel Ministry Of Agriculture & Rural Development Agricultural Res Organization Aro Vo Mogroside compounds, methods for their preparation, preparations including them and their uses
WO2016038550A1 (fr) 2014-09-11 2016-03-17 Novartis Ag Inhibition de prmt5 dans le traitement de maladies liées à une déficience en mtap
IL234638A0 (en) 2014-09-14 2014-12-02 Yeda Res & Dev NMDA receptor antagonists for the treatment of Gaucher disease
CA2944085C (fr) 2014-09-16 2018-04-10 Ease Charm Limited Anticorps anti-egfr et leurs utilisations
EP3230453B1 (fr) 2014-09-21 2020-05-20 Yissum Research and Development Company of the Hebrew University of Jerusalem Ltd. Freination du mir-132 pour le traitement de troubles lipidiques
MA40592A (fr) 2014-10-06 2016-04-14 Chemocentryx Inc Compositions et méthodes pour le traitement d'une maladie inflammatoire de l'intestin à l'aide d'une polythérapie à base d'inhibiteurs à petites molécules de récepteur 9 de chimiokine c-c (ccr9) et d'anticorps bloquants anti-intégrine alpha4beta7
EP3207156A1 (fr) 2014-10-13 2017-08-23 Life Technologies Corporation Procédés, kits et compositions pour déterminer des nombres de copies de gène
JP6767374B2 (ja) 2014-10-20 2020-10-14 ジェン−プローブ・インコーポレーテッド 赤血球溶解溶液
CN107105707B (zh) 2014-10-24 2022-07-22 杜邦营养生物科学有限公司 脯氨酸耐受性三肽基肽酶及其用途
EP3172329A1 (fr) 2014-10-24 2017-05-31 Danisco US Inc. Procédé de production d'alcool au moyen d'une tripeptidyl peptidase
ES2965744T3 (es) 2014-11-13 2024-04-16 Enzootic Holdings Ltd Inversión sexual funcional de crustáceos decápodos hembras
WO2016079736A2 (fr) 2014-11-17 2016-05-26 Yeda Research And Development Co. Ltd. Procédés de traitement de maladies associées à une fonction mitochondriale
JP2017533723A (ja) 2014-11-17 2017-11-16 イェダ リサーチ アンド ディベロップメント カンパニー リミテッドＹｅｄａ Ｒｅｓｅａｒｃｈ Ａｎｄ Ｄｅｖｅｌｏｐｍｅｎｔ Ｃｏ．Ｌｔｄ． マイクロバイオーム解析方法
JP6788586B2 (ja) 2014-11-19 2020-11-25 コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． Ｈｎｌを用いる診断方法
WO2016079739A2 (fr) 2014-11-20 2016-05-26 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Compositions et procédés de production de polypeptides présentant un schéma de glycosylation modifié dans des cellules végétales
CN107208070B (zh) 2014-11-26 2021-09-07 技术创新动力基金（以色列）有限合伙公司 细菌基因的靶向消除
CA2968808A1 (fr) 2014-11-27 2016-06-02 Danziger Innovations Ltd. Construction d'acide nucleique pour l'edition de genome
WO2016089920A1 (fr) 2014-12-01 2016-06-09 The Broad Institute, Inc. Procédé de détermination in situ de proximité d'acide nucléique
EP3227446A1 (fr) 2014-12-01 2017-10-11 Novartis AG Compositions et méthodes pour le diagnostic et le traitement du cancer de la prostate
KR102657306B1 (ko) 2014-12-08 2024-04-12 버그 엘엘씨 전립선암의 진단 및 치료에서 필라민을 포함하는 마커의 용도
KR102527180B1 (ko) 2014-12-10 2023-04-27 옵코 바이오로직스 리미티드 장기간 작용성 ctp-변형된 성장 호르몬 폴리펩타이드의 제조 방법
EP3230740B1 (fr) 2014-12-11 2025-05-21 Memed Diagnostics Ltd. Combinaisons de marqueurs de diagnostic d'infections et leurs méthodes d'utilisation
US10688330B2 (en) 2014-12-11 2020-06-23 Yeda Research And Development Co. Ltd. Isolated phosphotriesterase polypeptides, polynucleotides encoding same and uses thereof in treating or preventing organophosphate exposure associated damage
DK3193901T3 (en) 2014-12-23 2018-05-28 4D Pharma Res Ltd PIRIN POLYPEPTIDE AND IMMUNMODULATION
PE20171138A1 (es) 2014-12-23 2017-08-09 4D Pharma Res Ltd Modulacion inmunitaria
WO2016103269A1 (fr) 2014-12-23 2016-06-30 Ramot At Tel-Aviv University Ltd. Populations de cellules progénitrices neuronales et leurs procédés de production et d'utilisation
CA2972700A1 (fr) 2014-12-30 2016-07-07 Cell Cure Neurosciences Ltd. Procedes de traitement de maladies retiniennes
US20180011092A1 (en) 2014-12-30 2018-01-11 Cell Cure Neurosciences Ltd. Assessing retinal pigment epithelial cell populations
AU2015373050B2 (en) 2014-12-30 2022-09-29 Cell Cure Neurosciences Ltd. RPE cell populations and methods of generating same
NZ733912A (en) 2015-01-04 2023-04-28 Protalix Ltd Modified dnase and uses thereof
WO2016116935A1 (fr) 2015-01-21 2016-07-28 Yeda Research And Development Co. Ltd. Utilisation de la rasa2 en tant que marqueur pronostique et thérapeutique pour un mélanome
RU2723049C2 (ru) 2015-01-22 2020-06-08 Монсанто Текнолоджи Ллс Композиции и способы борьбы с leptinotarsa
JP6724023B2 (ja) 2015-02-09 2020-07-15 リサーチ ディベロップメント ファウンデーション 改善された補体活性化を示す操作された免疫グロブリンｆｃポリペプチド
CN114014930A (zh) 2015-02-13 2022-02-08 索伦托药业有限公司 结合ctla4的抗体治疗剂
JP6777966B2 (ja) 2015-02-17 2020-10-28 ダブテイル ゲノミクス エルエルシー 核酸配列アセンブリ
US10479825B2 (en) 2015-02-25 2019-11-19 Vanderbilt University Antibody-mediated neutralization of Marburg virus
US20180345047A1 (en) 2015-02-26 2018-12-06 Yeda Research And Development Co. Ltd. Method of promoting hair growth
CA2978631C (fr) 2015-03-09 2023-06-27 Agensys, Inc. Conjugues anticorps-medicament (cam) se liant aux proteines flt3
US11873483B2 (en) 2015-03-11 2024-01-16 The Broad Institute, Inc. Proteomic analysis with nucleic acid identifiers
EP3268475B1 (fr) 2015-03-11 2020-10-21 Yissum Research and Development Company of the Hebrew University of Jerusalem Ltd. Oligonucléotides leurres pour le traitement de maladies
IL237852A0 (en) 2015-03-19 2016-03-24 Yeda Res & Dev Antibodies against amphigoline, medical preparations containing them and their use
WO2016154540A1 (fr) 2015-03-26 2016-09-29 Dovetail Genomics Llc Conservation de la liaison physique dans le stockage d'adn
EP3273994B1 (fr) 2015-03-27 2021-12-01 University of Southern California Thérapie à base de lymphocytes t car dirigés contre le récepteur lhr pour le traitement des tumeurs solides
EP4218771A1 (fr) 2015-03-27 2023-08-02 Yeda Research and Development Co. Ltd Méthodes de traitement des maladies des motoneureones
US9612534B2 (en) 2015-03-31 2017-04-04 Tokyo Electron Limited Exposure dose homogenization through rotation, translation, and variable processing conditions
KR20170132293A (ko) 2015-03-31 2017-12-01 예다 리서치 앤드 디벨럽먼트 캄파니 리미티드 글루타메이트 옥살로아세테이트 트랜스아미나제 1（ｇｏｔ１） 제제와 이의 제조방법 및 용도
WO2016157192A1 (fr) 2015-04-01 2016-10-06 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) Extraits végétaux de crassifolium erodium l'her et leurs utilisations
ES2912276T3 (es) 2015-04-07 2022-05-25 Ela Pharma Ltd Composiciones para tratar y/o prevenir necrosis celular o tisular que seleccionan como diana específicamente catepsina C y/o CELA1 y/o CELA3A y/o enzimas estructuralmente relacionadas con las mismas
CN113527495A (zh) 2015-04-08 2021-10-22 索伦托药业有限公司 与cd38结合的抗体治疗剂
EP3081575A1 (fr) 2015-04-12 2016-10-19 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Anticorps anti-plasmodium pour parasite
WO2016174674A1 (fr) 2015-04-27 2016-11-03 The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center Molécules de ciblage egr1 dans le traitement de maladies inflammatoires et hyperprolifératives
CN108347945B (zh) 2015-04-29 2021-03-23 以色列农业和农村发展部农业研究组织(范卡尼中心) 抗植物致病组合物
US20190031759A1 (en) 2015-04-30 2019-01-31 Technion Research & Development Foundation Limited Chimeric antigen receptors and methods of their use
EP3292219B9 (fr) 2015-05-04 2022-05-18 Ramot at Tel-Aviv University Ltd. Procédés et kits pour fragmenter l'adn
CN106117288B (zh) 2015-05-08 2019-10-15 生捷科技控股公司 二硫键连接的可逆终止子
EP3294280A1 (fr) 2015-05-11 2018-03-21 Yeda Research and Development Co., Ltd. Inhibiteurs de citrine pour le traitement du cancer
US11219636B2 (en) 2015-05-17 2022-01-11 The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center Compositions and methods for treating cancer
ES3063952T3 (en) 2015-05-18 2026-04-21 Agensys Inc Antibodies that bind to axl proteins
WO2016187354A1 (fr) 2015-05-18 2016-11-24 Agensys, Inc. Anticorps se liant à des protéines axl
WO2016185457A1 (fr) 2015-05-19 2016-11-24 Yeda Research And Development Co. Ltd. Méthodes pour favoriser la lymphagiogenèse
WO2016185481A2 (fr) 2015-05-20 2016-11-24 Yeda Research And Development Co. Ltd. Procédé destiné à cibler des cellules sénescentes
EP3297727A1 (fr) 2015-05-21 2018-03-28 Yeda Research and Development Co. Ltd Populations bactériennes pour favoriser la santé
WO2016193969A2 (fr) 2015-05-29 2016-12-08 Opko Biologics Ltd. Variantes de l'oxyntomoduline pégylée
US10883103B2 (en) 2015-06-02 2021-01-05 Monsanto Technology Llc Compositions and methods for delivery of a polynucleotide into a plant
US10655136B2 (en) 2015-06-03 2020-05-19 Monsanto Technology Llc Methods and compositions for introducing nucleic acids into plants
CA2987992A1 (fr) 2015-06-04 2016-12-08 University Of Southern California Immunotherapie des cellules car ciblees par lym-1 et lym-2
NL2014935B1 (en) 2015-06-08 2017-02-03 Applied Immune Tech Ltd T cell receptor like antibodies having fine specificity.
LT3360559T (lt) 2015-06-15 2019-12-27 4D Pharma Research Limited Kompozicijos, apimančios bakterijų kamienus
MA41010B1 (fr) 2015-06-15 2020-01-31 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
PE20180243A1 (es) 2015-06-15 2018-01-31 4D Pharma Res Ltd Composiciones que comprenden cepas bacterianas
MA41060B1 (fr) 2015-06-15 2019-11-29 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
EP3662917A1 (fr) 2015-06-15 2020-06-10 4D Pharma Research Limited Compositions comprenant des souches bactériennes
WO2016203476A1 (fr) 2015-06-18 2016-12-22 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Procédés et compositions pour le diagnostic et le traitement d'un cancer urothélial
ES3063334T3 (en) 2015-06-18 2026-04-16 Yeda Res & Dev Conditioning protocols and use of same for tissue regeneration
KR102662956B1 (ko) 2015-06-19 2024-05-03 옵코 바이오로직스 리미티드 장기-작용성 응고 인자 및 그의 제조 방법
CA2990822A1 (fr) 2015-06-26 2016-12-29 Dupont Nutrition Biosciences Aps Aminopeptidases pour hydrolysats de proteines
GB2556004A (en) 2015-07-10 2018-05-16 Univ West Virginia Markers of stroke and stroke severity
AU2016291825B2 (en) 2015-07-16 2022-08-11 Yeda Research And Development Co. Ltd. Genetically modified anti-third party central memory T cells and use of same in immunotherapy
MX2017016844A (es) 2015-07-16 2018-08-15 Biokine Therapeutics Ltd Composiciones y procedimientos para tratar cancer.
EP3907231A1 (fr) 2015-07-19 2021-11-10 Yeda Research and Development Co., Ltd. Inhibiteurs séléctifs de na,k-atpase contenant des isoformes alpha2 et leur utilisation pour réduire la pression intraoculaire
WO2017015334A1 (fr) 2015-07-21 2017-01-26 Saint Louis University Compositions et méthodes pour diagnostiquer et traiter l'infertilité associée à l'endométriose
MX2018000844A (es) 2015-07-22 2018-07-06 Phytopharma Int Ltd Composiciones ingeribles por abejas, procedimientos para el uso de las mismas para producir miel y miel producida de esta manera.
EP3328995B1 (fr) 2015-07-29 2021-03-31 Hadasit Medical Research Services And Development Production à grande échelle de cellules de l'épithélium pigmentaire rétinien
WO2017021963A1 (fr) 2015-08-03 2017-02-09 Biokine Therapeutics Ltd. Agents de liaison de cxcr4 pour le traitement de maladies
EP3331572A4 (fr) 2015-08-04 2019-05-01 CD Diagnostics, Inc. Procédés de détection d'une nécrose liée à une réaction locale indésirable sur les tissus (altr)
WO2017021961A1 (fr) 2015-08-04 2017-02-09 Yeda Research And Development Co. Ltd. Procédés de criblage pour riborégulateurs et atténuateurs
EP3331995A1 (fr) 2015-08-05 2018-06-13 Cell Cure Neurosciences Ltd. Préparation de photorécepteurs pour le traitement de maladies rétiniennes
CN108138144A (zh) 2015-08-05 2018-06-08 细胞治疗神经科学有限公司 视网膜色素上皮细胞的制备
US10435457B2 (en) 2015-08-06 2019-10-08 President And Fellows Of Harvard College Microbe-binding molecules and uses thereof
US10639350B2 (en) 2015-08-10 2020-05-05 The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center Methods and pharmaceutical compositions for improving wound healing using CD24
EP3334831A1 (fr) 2015-08-13 2018-06-20 Forrest Innovations Ltd. Formulations et compositions d'administration d'acides nucléiques à des cellules végétales
AU2016308339A1 (en) 2015-08-18 2018-04-12 Baylor College Of Medicine Methods and compositions for altering function and structure of chromatin loops and/or domains
WO2017033188A1 (fr) 2015-08-24 2017-03-02 Yeda Research And Development Co. Ltd. Huile et biocarburant d'origine algale et leurs procédés de production
JP6989927B2 (ja) 2015-08-25 2022-02-03 プロセナ バイオサイエンシーズ リミテッド リン酸化アルファ－シヌクレインを検出するための方法
US10526408B2 (en) 2015-08-28 2020-01-07 Research Development Foundation Engineered antibody FC variants
CA3035810A1 (fr) 2015-09-02 2017-03-09 University Of Massachusetts Detection de loci de genes comprenant des repetitions matricielles de crispr et/ou des acides ribonucleiques mono-guides polychromatiques
US10765706B2 (en) 2015-09-03 2020-09-08 University Of South Florida Method of stem cell delivery into the brain during chronic disease using blood brain barrier permeabilizers
US11453864B2 (en) 2015-09-08 2022-09-27 University Of Massachusetts DNase H activity of Neisseria meningitidis Cas9
WO2017042816A1 (fr) 2015-09-10 2017-03-16 Yeda Research And Development Co. Ltd. Ablation de cellules dendritiques dont le test est positif pour la perforine, dans le traitement du cancer
US11001872B2 (en) 2015-09-22 2021-05-11 Shawn Clark Designing customized protein-specific buffer system
WO2017059108A1 (fr) 2015-09-29 2017-04-06 Htg Molecular Diagnostics, Inc. Procédés de sous-typage de lymphome diffus à grandes cellules b (ldgcb)
AU2016334401A1 (en) 2015-10-10 2018-04-26 Intrexon Corporation Improved therapeutic control of proteolytically sensitive, destabilized forms of interleukin-12
EP3913068B1 (fr) 2015-10-12 2023-08-02 Advanced Cell Diagnostics, Inc. Détection in situ de variants nucléotidiques dans des échantillons de bruit élevé et compositions et procédés associés
SG11201803289VA (en) 2015-10-19 2018-05-30 Dovetail Genomics Llc Methods for genome assembly, haplotype phasing, and target independent nucleic acid detection
EP3365376A1 (fr) 2015-10-25 2018-08-29 Yeda Research and Development Co., Ltd. Anticorps ciblant la quiescine sulfhydryle oxydase (qsox1) et leurs utilisations
HUE070900T2 (hu) 2015-10-26 2025-07-28 Cell Cure Neurosciences Ltd Eljárás retinális pigmentepitélium-sejtek elõállítására
BR112018008601A2 (pt) 2015-10-27 2018-10-30 Jay Pharma Inc composições compreendendo o canabidiol e segundos agentes terapêuticos para o tratamento de câncer
IL242380A0 (en) 2015-10-29 2016-02-01 Yeda Res & Dev A method of inducing cardiomyocytes proliferation and treating heart diseases
WO2017077539A1 (fr) 2015-11-03 2017-05-11 Ariel-University Research And Development Company Ltd. Compositions destinées à la régénération et à la réparation de tissu nerveux
WO2017083296A1 (fr) 2015-11-09 2017-05-18 The Children's Hospital Of Philadelphia Glypicane 2 à utiliser en tant que marqueur cancéreux et cible thérapeutique
EP3374524B1 (fr) 2015-11-11 2025-01-29 Ramot at Tel-Aviv University Ltd. Procédés de détection de la 5-hydroxyméthylcytosine et diagnostic du cancer
MA41013A (fr) 2015-11-20 2017-08-30 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
GB201520497D0 (en) 2015-11-20 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520638D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520631D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
HK1254740A1 (zh) 2015-11-30 2019-07-26 Kadimastem Ltd. 分化和纯化胰腺内分泌细胞的方法
KR102803158B1 (ko) 2015-12-02 2025-05-08 주식회사 에스티큐브앤컴퍼니 Btn1a1에 면역특이적으로 결합하는 항체와 분자 및 그의 치료 용도
EP3176183A1 (fr) 2015-12-02 2017-06-07 Yeda Research and Development Co. Ltd Compositions et procédés pour traiter un cancer non résistant à un inhibiteur de la tyrosine kinase (tki)
JP7227007B2 (ja) 2015-12-02 2023-02-21 ストサイエンシス， インコーポレイテッド グリコシル化ｂｔｌａ（ｂ－及びｔ－リンパ球減弱因子）に特異的な抗体
ES2902477T3 (es) 2015-12-04 2022-03-28 Univ Texas Péptidos SLC45A2 para inmunoterapia
US11213609B2 (en) 2015-12-16 2022-01-04 Ramot At Tel-Aviv University Ltd. Particles comprising decellularized omentum
KR20250112919A (ko) 2015-12-21 2025-07-24 노파르티스 아게 타우 발현을 감소시키기 위한 조성물 및 방법
EP3393524B1 (fr) 2015-12-22 2022-04-06 The Regents of The University of Colorado, A Body Corporate Protection d'arn de la dégradation à l'aide d'arn viraux modifiés
US10561706B2 (en) 2015-12-28 2020-02-18 B. G. Negev Technologies And Applications Isolated polypeptide and compositions comprising same
AU2017204950A1 (en) 2016-01-06 2018-08-16 Yeda Research And Development Co. Ltd. Compositions and methods for treating malignant, autoimmune and inflammatory diseases
WO2017122203A1 (fr) 2016-01-11 2017-07-20 Technion Research & Development Foundation Limited Méthodes de détermination du pronostic de septicémie et traitement associé
WO2017125931A1 (fr) 2016-01-21 2017-07-27 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) Plantes parthénocarpiques et procédés de production de celles-ci
IL243839B (en) 2016-01-28 2018-01-31 Sp Nano Ltd Conductive wires
IL243838A (en) 2016-01-28 2017-07-31 Sp Nano Ltd The composition containing sp1 protein and carbon nanoparticles and its uses
ES2986360T3 (es) 2016-01-29 2024-11-11 Yuhan Corp Proteínas de unión a antígeno que se unen a PD-L1
WO2017130205A1 (fr) 2016-01-31 2017-08-03 Hadasit Medical Research Services And Development Ltd. Populations de cellules souches pluripotentes ayant une composition de chromosomes sexuels non identiques et leurs utilisations
RU2762089C2 (ru) 2016-02-04 2021-12-15 Иеда Рисеч Энд Девелопмент Ко. Лтд. ПЕПТИДЫ И ИХ ПРИМЕНЕНИЕ В ЛЕЧЕНИИ ЗАБОЛЕВАНИЙ, НАРУШЕНИЙ ИЛИ СОСТОЯНИЙ, АССОЦИИРОВАННЫХ С МУТАНТНЫМ р53
WO2017139415A2 (fr) 2016-02-11 2017-08-17 Qiagen Waltham, Inc. Composés piégeurs pour un séquençage par synthèse amélioré
WO2017139419A1 (fr) 2016-02-11 2017-08-17 Qiagen Waltham, Inc. Additifs polyphénoliques dans le séquençage par synthèse
WO2017138008A2 (fr) 2016-02-14 2017-08-17 Yeda Research And Development Co. Ltd. Procédés de modulation de l'exocytose de protéines et utilisations associées en thérapie
US20190142875A1 (en) 2016-02-14 2019-05-16 Yeda Research And Development Co. Ltd. Microbiome-based diagnosis, prediction and treatment of relapsing obesity
BR112018016757A2 (pt) 2016-02-16 2020-05-19 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. análogos de fenilalanina não-proteícos para inibir crescimento de cianobacteria e de plantas.
WO2017143156A1 (fr) 2016-02-19 2017-08-24 Genisphere Llc Vecteurs d'acide nucléique et leurs procédés thérapeutiques d'utilisation
WO2017147186A1 (fr) 2016-02-22 2017-08-31 Ursure, Inc. Système et méthode de détection d'agents thérapeutiques pour surveiller l'adhésion à un schéma thérapeutique
EP3420075A4 (fr) 2016-02-23 2019-10-16 Chaya Brodie Production de cellules souches cancéreuses et leur utilisation
US10975417B2 (en) 2016-02-23 2021-04-13 Dovetail Genomics, Llc Generation of phased read-sets for genome assembly and haplotype phasing
MX2018009216A (es) 2016-02-25 2018-11-09 Dupont Nutrition Biosci Aps Metodo para producir un hidrolizado de proteina empleando una tripeptidil peptidasa de aspergillus fumigatus.
AU2017224122B2 (en) 2016-02-26 2024-04-11 The Board Of Regents Of The University Of Texas System Connexin (Cx) 43 hemichannel-binding antibodies and uses thereof
RU2756275C2 (ru) 2016-03-01 2021-09-29 Юссум Рисёрч Девелопмент Компани Оф Зэ Хибру Юниверсити Оф Иерусалим Лтд. Антитела, специфические к рецептору полиовируса (pvr) человека
WO2017149547A1 (fr) 2016-03-03 2017-09-08 Memed Diagnostics Ltd. Analyse d'arn pour diagnostiquer un type d'infection
GB201612191D0 (en) 2016-07-13 2016-08-24 4D Pharma Plc Compositions comprising bacterial strains
MX373290B (es) 2016-03-04 2020-06-18 4D Pharma Plc Composiciones que comprenden cepas bacterianas.
WO2017153982A1 (fr) 2016-03-06 2017-09-14 Yeda Research And Development Co. Ltd. Procédé de modulation de la myélinisation
IL244649A0 (en) 2016-03-17 2016-06-30 Yeda Res & Dev Methods for the isolation of barrel-like proteases and the identification of peptides that are cleaved by Alidan
CN109462996A (zh) 2016-03-17 2019-03-12 西达-赛奈医疗中心 通过rnaset2诊断炎性肠病的方法
EP3433262A4 (fr) 2016-03-25 2019-11-20 Muralidhar Reddy Moola Synthèse combinatoire et développement de biomarqueurs
CN109195991B (zh) 2016-03-29 2023-10-31 斯特库比股份有限公司 对糖基化pd-l1特异的双重功能抗体及其使用方法
WO2017173091A1 (fr) 2016-03-30 2017-10-05 Musc Foundation For Research Development Méthodes pour le traitement et le diagnostic du cancer par le ciblage d'une protéine à prédominance de répétitions de glycoprotéine a (garp) et la mise en œuvre d'une immunothérapie efficace seule ou en association
US11262358B2 (en) 2016-04-06 2022-03-01 Technion Research & Development Foundation Limited Infiltrating immune cell proportions predict anti-TNF response in colon biopsies
EP3448998B1 (fr) 2016-04-27 2020-06-03 Gen-Probe Incorporated Réactif de lyse de cellules sanguines
WO2017194589A1 (fr) 2016-05-10 2017-11-16 Vib Vzw Inhibition du dysfonctionnement synaptique précoce à médiation par tau
WO2017197300A1 (fr) 2016-05-13 2017-11-16 Dovetail Genomics Llc Récupération d'informations de liaison de longue portée à partir d'échantillons conservés
US11919971B2 (en) 2016-05-16 2024-03-05 President And Fellows Of Harvard College Aqueous biomolecule coupling on CO2-plasma-activated surfaces
IL263232B2 (en) 2016-05-22 2024-04-01 Weedout Ltd Compositions, kits and methods for weed control
WO2017203520A1 (fr) 2016-05-22 2017-11-30 Yeda Research And Development Co. Ltd. Méthodes d'utilisation de cellules pulmonaires pour transplantation et induction de tolérance
IL245861A0 (en) 2016-05-25 2016-09-04 Yeda Res & Dev Use of substances to treat drug-resistant tumors
WO2017201731A1 (fr) 2016-05-27 2017-11-30 Beijing Vdjbio Co., Ltd. Anticorps, composition et kits les comprenant et leurs procédés d'utilisation
US20190100732A1 (en) 2016-06-02 2019-04-04 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Assay for the removal of methyl-cytosine residues from dna
US11820833B2 (en) 2016-06-05 2023-11-21 Tel Hashomer Medical Research Infrastructure And Services Ltd. Peptides that inhibit binding of EPCR to its ligand to treat inflammation
US20200185063A1 (en) 2016-06-05 2020-06-11 Berg Llc Systems and methods for patient stratification and identification of potential biomarkers
US11274345B2 (en) 2016-06-07 2022-03-15 The Board Of Trustees Of The Leland Stanford Junior University Methods for diagnosis of bacterial and viral infections
EP3468610A1 (fr) 2016-06-09 2019-04-17 OPKO Biologics Ltd. Formulation d'oxyntomoduline à action prolongée, et procédés de production et procédés d'administration de cette dernière
EP3472342A1 (fr) 2016-06-19 2019-04-24 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Criblage de la résistance à la chimiothérapie dans des cellules haploïdes humaines
WO2017222911A1 (fr) 2016-06-20 2017-12-28 The Board Of Trustees Of The Leland Stanford Junior University Arn circulaires et leur utilisation dans l'immunomodulation
EP3475414B1 (fr) 2016-06-27 2025-03-26 Yeda Research and Development Co. Ltd Cellules veto generer de cellules t memoires
CN109416357B (zh) 2016-06-30 2022-07-15 西门子医疗系统荷兰有限公司 用于检测包含多个细胞的体液样本中的分析物的设备、系统和方法
WO2018011796A1 (fr) 2016-07-10 2018-01-18 Memed Diagnostics Ltd. Diagnostic précoce d'infections
WO2018011795A1 (fr) 2016-07-10 2018-01-18 Memed Diagnostics Ltd. Signatures de protéines permettant d'établir la différence entre des infections bactériennes et des infections virales
EP3481967A4 (fr) 2016-07-11 2020-04-22 Bonus Therapeutics Ltd. Compositions cellulaires pour la régénération tissulaire
IL320653A (en) 2016-07-11 2025-07-01 Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd Systems and methods for growing cells in vitro
IL246722A0 (en) 2016-07-11 2016-09-29 Yeda Res & Dev Combination therapy to increase endogenous nitric oxide (no) synthesis
EP4303228B1 (fr) 2016-07-11 2026-05-27 OPKO Biologics Ltd. Facteur vii de coagulation à action prolongée et procédés de production associés
TWI802545B (zh) 2016-07-13 2023-05-21 英商４Ｄ製藥有限公司 包含細菌菌株之組合物
EP3484517B1 (fr) 2016-07-18 2025-07-02 Ramot at Tel-Aviv University Ltd. Plate-forme modulaire pour thérapie ciblée
US11746152B2 (en) 2016-07-20 2023-09-05 Stcube, Inc. Methods of cancer treatment and therapy using a combination of antibodies that bind glycosylated PD-L1
EP3488242B1 (fr) 2016-07-20 2025-06-11 Vib Vzw Agents thérapeutiques pour le traitement de troubles neurologiques et psychiatriques
WO2018020489A1 (fr) 2016-07-24 2018-02-01 Yeda Research And Development Co. Ltd. Méthodes et kits pour analyser des fragments de liaison à l'adn liés à l'adn
ES2965761T3 (es) 2016-08-08 2024-04-16 Tech Innovation Momentum Fund Israel Limited Partnership Sistemas bacterianos para el análisis de polipéptidos ubiquitilados
EP3497239B1 (fr) 2016-08-10 2026-05-27 Ramot at Tel-Aviv University Ltd. Analyse de l'état de méthylation et du nombre de copies
CN109844532B (zh) 2016-08-10 2022-06-17 米密德诊断学有限公司 分析生物数据的系统和方法
JP7014449B2 (ja) 2016-08-14 2022-02-01 ラモット アット テル アビブ ユニバーシティ， リミテッド 神経障害を処置するための間葉系細胞由来エキソソーム
IL247368A0 (en) 2016-08-18 2016-11-30 Yeda Res & Dev Diagnostic and therapeutic uses of exosomes
WO2018037416A1 (fr) 2016-08-25 2018-03-01 Yeda Research And Development Co. Ltd. Procédés et compositions pour le traitement de maladies auto-immunes
CA3035324A1 (fr) 2016-08-28 2018-03-08 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) Procede de lutte contre les infections fongiques chez les plantes
JP2020501506A (ja) 2016-09-07 2020-01-23 イッサム リサーチ デベロップメント カンパニー オブ ザ ヘブリュー ユニバーシティー オブ エルサレム エルティーディー． 抗ＮＫｐ４６抗体およびその治療的使用
EP3512943B1 (fr) 2016-09-14 2023-04-12 Yeda Research and Development Co. Ltd. Crisp-seq, procédé intégré pour séquençage massivement parallèle d'arn unicellulaire et criblages regroupés par crispr
WO2018060998A1 (fr) 2016-09-29 2018-04-05 Memed Diagnostics Ltd. Méthodes de pronostic et de traitement
IL248468A0 (en) 2016-10-13 2017-01-31 Technion Res & Dev Foundation Use of caspase-3 inhibitors and caspase-3 activators in the manufacture of medicament for treating cancer and wound healing
IL248385A0 (en) 2016-10-18 2017-02-01 Yeda Res & Dev Treatment of circadian rhythm disorder
EP3534953A4 (fr) 2016-11-02 2020-10-07 Vanderbilt University Anticorps contre le virus zika humain et leurs procédés d'utilisation
WO2018085679A1 (fr) 2016-11-04 2018-05-11 Stave James W Détection directe de micro-organismes dans des échantillons de patient par dosage immunologique
CN110121563A (zh) 2016-11-09 2019-08-13 奇根科学有限责任公司 在边合成边测序中作为成像试剂的光保护混合物
US20190359956A1 (en) 2016-11-10 2019-11-28 Yeda Research And Development Co. Ltd. Phosphotriesterases for treating or preventing organophosphate exposure associated damage
IL294410B2 (en) 2016-11-23 2024-02-01 Chemocentryx Inc A method for the treatment of focal segmental tuberous sclerosis
CN110234765A (zh) 2016-11-28 2019-09-13 耶达研究及发展有限公司 分离的多核苷酸和多肽及使用它们来表达感兴趣的表达产物的方法
US20180150597A1 (en) 2016-11-29 2018-05-31 Genomic Vision Sa Method for optimal design of polynucleotides sequences for analysis of specific events in any genetic region of interest
US20190343782A1 (en) 2016-11-30 2019-11-14 Yeda Research And Development Co. Ltd. Methods of treating liver toxicity and disorders
CA3026989C (fr) 2016-12-01 2023-07-11 Ramot At Tel-Aviv University Ltd. Traitement combine pour lesions nerveuses
ES3057136T3 (en) 2016-12-05 2026-02-26 Nuritas Ltd Compositions comprising peptide wkdeagkplvk
EP3329905A1 (fr) 2016-12-05 2018-06-06 Nuritas Limited Compositions cosmötiques topiques contenant d'un oligpeptide contre le vieillisement de la peau
EP3329930A1 (fr) 2016-12-05 2018-06-06 Nuritas Limited Compositions pharmaceutiques
GB201621123D0 (en) 2016-12-12 2017-01-25 4D Pharma Plc Compositions comprising bacterial strains
ES3064681T3 (en) 2017-01-18 2026-04-28 Yeda Res & Dev Genetically modified veto cells and use of same in immunotherapy
IL268274B1 (en) 2017-01-25 2026-07-01 Mor Research Applic Ltd Methods for diagnosing malignant diseases
KR102607101B1 (ko) 2017-01-26 2023-11-29 제트엘아이피 홀딩 리미티드 Cd47 항원 결합 유닛 및 그것의 사용
EP3574114B1 (fr) 2017-01-26 2022-06-29 Oklahoma Medical Research Foundation Biomarqueurs de l'activité, de l'intensité et de l'éruption de la maladie du lupus érythémateux disséminé
WO2018144425A1 (fr) 2017-01-31 2018-08-09 Vanderbilt University Génération d'anticorps monoclonaux ige spécifiques d'allergènes et d'helminthes humains pour une utilisation diagnostique et thérapeutique
IL250479A0 (en) 2017-02-06 2017-03-30 Sorek Rotem Genetically engineered cells expressing a disarm system that confers resistance to phages and methods for their production
WO2018146162A1 (fr) 2017-02-07 2018-08-16 Academisch Medisch Centrum Biomarqueur moléculaire pour le pronostic de patients atteints de septicémie
WO2018146679A2 (fr) 2017-02-08 2018-08-16 Hadasit Medical Research Services And Development Ltd. Cellules photoréceptrices pour le traitement de maladies rétiniennes
IL250916A0 (en) 2017-03-02 2017-06-29 Geiger Benjamin Methods for growing t cells in culture and their use
WO2018163051A1 (fr) 2017-03-06 2018-09-13 Novartis Ag Méthodes de traitement du cancer à expression d'ubb réduite
WO2018167778A1 (fr) 2017-03-12 2018-09-20 Yeda Research And Development Co. Ltd. Procédés de diagnostic et de pronostic du cancer
WO2018167780A1 (fr) 2017-03-12 2018-09-20 Yeda Research And Development Co. Ltd. Méthodes de diagnostic et de traitement du cancer
US20200085882A1 (en) 2017-03-16 2020-03-19 Lineage Cell Therapeutics, Inc. Methods for measuring therapeutic effects of retinal disease therapies
WO2018185760A1 (fr) 2017-04-05 2018-10-11 Yeda Research And Development Co. Ltd. Système de culture ex-vivo et procédés d'utilisation de celui-ci
IL252151A0 (en) 2017-05-07 2017-07-31 Fainzilber Michael Treatment of stress disorders
US20210003570A1 (en) 2017-05-10 2021-01-07 Rowan University Diagnostic biomarkers for detecting, subtyping, and/or assessing progression of multiple sclerosis
WO2018207184A2 (fr) 2017-05-10 2018-11-15 Ariel Scientific Innovations Ltd. Procédés de purification d'anticorps
WO2018216006A1 (fr) 2017-05-21 2018-11-29 The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center Combinaison de marqueurs pour diagnostiquer un cancer
MA48940A (fr) 2017-05-22 2020-04-08 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
EP3634991A1 (fr) 2017-05-23 2020-04-15 Technion Research & Development Foundation Limited Agents inhibant la dimérisation de gads et leurs procédés d'utilisation
MA41708A (fr) 2017-05-24 2020-04-08 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
CN111148762A (zh) 2017-05-31 2020-05-12 斯特库伯株式会社 免疫特异性结合至btn1a1的抗体和分子及其治疗性用途
GB201708662D0 (en) 2017-05-31 2017-07-12 Tropic Biosciences Uk Ltd Compositions and methods for increasing shelf-life of banana
EP3630973A1 (fr) 2017-05-31 2020-04-08 Tropic Biosciences UK Limited Méthodes de sélection de cellules comprenant des événements d'édition de génome
CN111051346A (zh) 2017-05-31 2020-04-21 斯特库伯株式会社 使用免疫特异性结合btn1a1的抗体和分子治疗癌症的方法
GB201708665D0 (en) 2017-05-31 2017-07-12 Tropic Biosciences Uk Ltd Compositions and methods for increasing extractability of solids from coffee beans
JP2020522562A (ja) 2017-06-06 2020-07-30 ストキューブ アンド シーオー．， インコーポレイテッド Ｂｔｎ１ａ１又はｂｔｎ１ａ１リガンドに結合する抗体及び分子を用いて癌を治療する方法
WO2018229764A1 (fr) 2017-06-13 2018-12-20 Yeda Research And Development Co. Ltd. Traitement de la sclérose en plaques avancée ou progressive
JP2020523326A (ja) 2017-06-14 2020-08-06 フォーディー ファーマ リサーチ リミテッド４Ｄ Ｐｈａｒｍａ Ｒｅｓｅａｒｃｈ Ｌｉｍｉｔｅｄ 細菌株を含む組成物
TWI767013B (zh) 2017-06-14 2022-06-11 英商4D製藥研究有限公司 包含細菌品系之組成物
PL3638271T3 (pl) 2017-06-14 2021-03-22 4D Pharma Research Limited Kompozycje zawierające szczepy bakteryjne
US12140592B2 (en) 2017-06-16 2024-11-12 Oklahoma Medical Research Foundation Biomarkers for assessing risk of transitioning to systemic lupus erythematosus classification and disease pathogenesis
EP4403646A3 (fr) 2017-07-13 2025-01-08 Yissum Research and Development Company of the Hebrew University of Jerusalem Ltd. Cibles d'adn en tant que marqueurs de méthylation spécifiques de tissu
WO2019012544A1 (fr) 2017-07-13 2019-01-17 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Stratégie de pcr en gouttelettes à double sonde pour la détection spécifique de molécules d'adn circulantes spécifiques d'un tissu
EP3652342A1 (fr) 2017-07-13 2020-05-20 Yissum Research and Development Company of the Hebrew University of Jerusalem Ltd. Détection d'adn spécifique d'un tissu
WO2019018747A1 (fr) 2017-07-20 2019-01-24 Trustees Of Boston University Dosage de détection du ténofovir
EP4085919A3 (fr) 2017-07-21 2023-02-08 Novartis AG Compositions et procédés permettant de traiter un cancer
IL253642A0 (en) 2017-07-24 2017-09-28 Seger Rony Combined treatment for cancer
WO2019030759A1 (fr) 2017-08-08 2019-02-14 Technology Innovation Momentum Fund (Israel) Limited Partnership Protéine tronquée résistante au chloramphénicol et ses utilisations
IL253984A0 (en) 2017-08-14 2017-09-28 Yeda Res & Dev Immunotherapy against aranviruses that bind through transferrin receptor 1 (tfr1
MX2020001958A (es) 2017-08-21 2020-09-25 Savicell Diagnostic Ltd Procedimientos de diagnostico y tratamiento del cancer de pulmon.
US11692166B2 (en) 2017-08-23 2023-07-04 Technion Research & Development Foundation Limited Compositions and methods for improving alcohol tolerance in yeast
SG11202000387YA (en) 2017-08-25 2020-03-30 Five Prime Therapeutics Inc B7-h4 antibodies and methods of use thereof
US11421029B2 (en) 2017-09-01 2022-08-23 Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. Recombinant bispecific antibodies to PD-L1 and CTLA-4
JP2020533976A (ja) 2017-09-05 2020-11-26 グラディエーター バイオサイエンシーズ インコーポレイテッド エキソソームを標的化する方法
WO2019055825A1 (fr) 2017-09-15 2019-03-21 The Regents Of The University Of California Inhibition de l'aminoacylase 3 (aa3) dans le traitement du cancer
JP7422069B2 (ja) 2017-09-19 2024-01-25 トロピック バイオサイエンシーズ ユーケー リミテッド 真核細胞において遺伝子発現をサイレンシングするための非コードｒｎａ分子の特異性の改変
AU2018336161A1 (en) 2017-09-19 2020-03-26 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) Genome-edited birds
KR20240017986A (ko) 2017-09-26 2024-02-08 더 리전트 오브 더 유니버시티 오브 캘리포니아 암 치료를 위한 조성물 및 방법
WO2019071054A1 (fr) 2017-10-04 2019-04-11 The Broad Institute, Inc. Procédés et compositions permettant de modifier la fonction et la structure de boucles et/ou de domaines de chromatine
MX386699B (es) 2017-10-11 2025-03-19 Chemocentryx Inc Tratamiento de glomerulosclerosis segmentaria focal con antagonistas ccr2
EP3694545A4 (fr) 2017-10-11 2021-12-01 Board Of Regents, The University Of Texas System Anticorps pd-l1 humains et leurs procédés d'utilisation
WO2019075385A1 (fr) 2017-10-12 2019-04-18 Board Of Regents, The University Of Texas System Compositions de lymphocytes t pour l'immunothérapie
CN111565731B (zh) 2017-10-24 2024-03-08 达莉亚·伊兰妮 治疗缺血性疾病的方法
CN111587123A (zh) 2017-11-09 2020-08-25 品通治疗有限公司 用于生成和使用人源化构象特异性磷酸化的τ抗体的方法和组合物
IL255664A0 (en) 2017-11-14 2017-12-31 Shachar Idit Hematopoietic stem cells with enhanced properties
IL274979B2 (en) 2017-11-29 2024-07-01 Univ Ramot Methods for the prevention and treatment of neurogenic seizures
BR112020010830A2 (pt) 2017-11-29 2020-11-10 Weedout Ltd. composições, kits e métodos para controlar erva daninha do gênero amaranthus
EP3716993A1 (fr) 2017-12-03 2020-10-07 Yeda Research and Development Co. Ltd Traitement d'une maladie cardiaque ischémique
CN109870581B (zh) 2017-12-04 2021-05-04 厦门万泰凯瑞生物技术有限公司 一种定量检测HBsAg的试剂盒及方法
CA3085324A1 (fr) 2017-12-15 2019-06-20 Syngenta Participations Ag Ligands non-anticorps pour la detection de proteines cibles
WO2019116376A1 (fr) 2017-12-17 2019-06-20 Yeda Research And Development Co. Ltd. Modulateurs du complexe signalosome cop9 (csn) et leurs utilisations
EP3731965A1 (fr) 2017-12-28 2020-11-04 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Procédé pour reproduire des rythmes circadiens sur une puce microfluidique
BR112020013238A2 (pt) 2017-12-29 2020-12-01 Cell Cure Neurosciences Ltd. composição e método para formular células do epitélio pigmentar da retina bem como uso da dita composição para tratar uma condição retiniana
US11851478B2 (en) 2018-01-05 2023-12-26 Vanderbilt University Antibody-mediated neutralization of chikungunya virus
CA3274788A1 (en) 2018-01-29 2026-03-02 Lavie Bio Ltd. Plant microbial preparations, compositions and formulations comprising same and uses thereof
IL257225A (en) 2018-01-29 2018-04-09 Yeda Res & Dev Treatment of sarcoma
IL257269A (en) 2018-01-31 2018-04-09 Olender Tsviya Signaling is directed to the endoplasmic reticulum
WO2019152543A1 (fr) 2018-01-31 2019-08-08 Dovetail Genomics, Llc Préparation d'échantillon pour récupération de liaison d'adn
EP3749368A1 (fr) 2018-02-08 2020-12-16 Yeda Research and Development Co. Ltd Procédés d'identification et d'utilisation d'agents pour traiter des maladies associées à un dysfonctionnement de la barrière intestinale
WO2019155459A1 (fr) 2018-02-08 2019-08-15 Yeda Research And Development Co. Ltd. Inhibiteurs du protéasome 20s
WO2019155041A1 (fr) 2018-02-12 2019-08-15 Vib Vzw ANTICORPS COMPLEXES Gβγ ET LEURS UTILISATIONS
WO2019165077A1 (fr) 2018-02-21 2019-08-29 Five Prime Therapeutics, Inc. Formulations d'anticorps b7-h4
WO2019165217A1 (fr) 2018-02-22 2019-08-29 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Cd153 et/ou cd30 dans une infection
US11571433B2 (en) 2018-02-23 2023-02-07 Carmel Haifa University Economic Corporation Ltd. Methods for treating memory impairment and cognitive dysfunction
US20200408761A1 (en) 2018-02-28 2020-12-31 The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center Methods of diagnosing and treating bladder cancer
KR20200144094A (ko) 2018-03-02 2020-12-28 파이브 프라임 테라퓨틱스, 인크. B7-h4 항체 및 이의 사용 방법
EP3765034A1 (fr) 2018-03-12 2021-01-20 Yeda Research and Development Co. Ltd Traitement d'une maladie cardiaque
KR20200131846A (ko) 2018-03-14 2020-11-24 메모리얼 슬로안 케터링 캔서 센터 항-폴리시알산 항체 및 그 용도
EP4501355A3 (fr) 2018-03-23 2025-04-30 Board Of Regents, The University Of Texas System Anticorps à double spécificité pour pd-l1 et pd-l2 et leurs procédés d'utilisation
EP3768723A4 (fr) 2018-03-23 2021-12-29 Board of Regents, The University of Texas System Anticorps à double spécificité pour pd-l1 et pd-l2 humains et leurs procédés d'utilisation
WO2019186569A1 (fr) 2018-03-29 2019-10-03 Yeda Research And Development Co. Ltd. Utilisation de gradients de champ électrique pour commander l'expression génique
KR102995657B1 (ko) 2018-03-29 2026-07-28 테크니온 리서치 엔드 디벨로프먼트 화운데이션 엘티디. Pten 억제제를 포함하는 소포 및 이의 용도
IL258467A (en) 2018-03-29 2018-07-04 Ilana Kolodkin Gal Methods of disrupting a biofilm and/or preventing formation of same
CN112292457A (zh) 2018-04-09 2021-01-29 领先细胞医疗诊断有限公司 用于原位检测核酸的进一步增强信号放大的方法
US11884725B2 (en) 2018-04-24 2024-01-30 Ampsource Biopharma Shanghai Inc. Antibody against TIM-3 and application thereof
GB201807192D0 (en) 2018-05-01 2018-06-13 Tropic Biosciences Uk Ltd Compositions and methods for reducing caffeine content in coffee beans
US20210123016A1 (en) 2018-05-02 2021-04-29 Novartis Ag Regulators of human pluripotent stem cells and uses thereof
WO2019220441A1 (fr) 2018-05-15 2019-11-21 Hadasit Medical Research Services And Development Ltd. Compositions et méthodes de traitement du cancer résistant à un agent anticancéreux
IL259392A (en) 2018-05-15 2018-08-01 Yeda Res & Dev Vaccination with cancer neoantigens
WO2019222618A1 (fr) 2018-05-17 2019-11-21 The Trustees Of Columbia University In The City Of New York Méthodes de traitement, prévention et détection du pronostic du cancer colorectal
BR112020023955A2 (pt) 2018-05-27 2021-02-23 Biolinerx Ltd. agi-134 combinado com um inibidor de ponto de controle para o tratamento de tumores sólidos
AU2019277920A1 (en) 2018-05-31 2021-01-07 Immunity Pharma Ltd. Compositions and methods of using same for treating amyotrophic lateral sclerosis (ALS)
EP3800998A1 (fr) 2018-06-07 2021-04-14 The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Center) Procédés de régénération et de transformation de cannabis
EP3802839A1 (fr) 2018-06-07 2021-04-14 The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Center) Constructions d'acide nucléique et procédés d'utilisation de celles-ci
EP3820498A1 (fr) 2018-06-14 2021-05-19 University College Cork-National University of Ireland Cork Peptide pour le traitement de maladies
TW202016144A (zh) 2018-06-21 2020-05-01 日商第一三共股份有限公司 包括cd3抗原結合片段之組成物及其用途
WO2020003311A1 (fr) 2018-06-25 2020-01-02 Yeda Research And Development Co. Ltd. Systèmes et procédés permettant d'améliorer l'efficacité de l'édition génomique
AU2019297677B2 (en) 2018-07-04 2024-11-07 Ukko Inc. Methods of de-epitoping wheat proteins and use of same for the treatment of celiac disease
US20210269860A1 (en) 2018-07-08 2021-09-02 Yeda Research And Development Co. Ltd. Person-specific assessment of probiotics responsiveness
CA3104780A1 (fr) 2018-07-11 2020-01-16 Kahr Medical Ltd. Proteine de fusion du variant de sirpalpha-4-1bbl et procedes d'utilisation associes
JP7395517B2 (ja) 2018-07-11 2023-12-11 イミュニティ ファルマ リミテッド ペプチド化合物およびその治療的用途
WO2020026241A1 (fr) 2018-07-31 2020-02-06 Collplant Ltd. Événement transgénique du tabac et procédés de détection et d'utilisation associés
IL261156A (en) 2018-08-14 2020-02-27 Fass Deborah Chimeric quiescin sulfhydryl oxidase (qsox1) antibodies and uses of same
EP3841201A1 (fr) 2018-08-24 2021-06-30 Yeda Research and Development Co. Ltd Procédés de modulation de la polarisation de macrophages m2 et leur utilisation en thérapie
AU2019339469A1 (en) 2018-09-13 2021-03-11 Immune-Onc Therapeutics, Inc. Novel LILRB4 antibodies and uses thereof
JP7520820B2 (ja) 2018-09-20 2024-07-23 イェダ リサーチ アンド ディベロップメント カンパニー リミテッド 筋萎縮性側索硬化症の治療方法
WO2020065647A1 (fr) 2018-09-25 2020-04-02 Biolinerx Ltd. Procédés de sélection d'un traitement contre un cancer associé aux récepteurs cxcr4
US12258368B2 (en) 2018-09-28 2025-03-25 Centrillion Technology Holdings Corporation Disulfide-linked reversible terminators
AU2019361923B2 (en) 2018-10-15 2026-07-09 Five Prime Therapeutics, Inc. Combination therapy for cancer
CN113166743B (zh) 2018-10-15 2026-04-07 马萨诸塞大学 Nme2cas9-脱氨酶融合蛋白的可编程dna碱基编辑
EP3867645B1 (fr) 2018-10-18 2024-06-05 Oklahoma Medical Research Foundation Biomarqueurs d'indice immunitaire d'activité de maladie du lupus érythémateux disséminé (sle) qui caractérise une activité de maladie
US12510539B2 (en) 2018-10-18 2025-12-30 Progentec Diagnostics, Inc. Biomarkers for a systemic lupus erythematosus (SLE) disease activity immune index that characterizes disease activity
JP7401538B2 (ja) 2018-10-22 2023-12-19 シャンハイ、ケンパーソー、バイオテクノロジー、カンパニー、リミテッド 抗ｃｌｄｎ１８．２抗体およびその使用
JP2022506108A (ja) 2018-10-23 2022-01-17 グリカルディアル ダイアグノスティクス エセ． エレ． グリコシル化ＡｐｏＪに特異的な抗体およびその使用
IL262658A (en) 2018-10-28 2020-04-30 Memorial Sloan Kettering Cancer Center Prevention of age related clonal hematopoiesis and diseases associated therewith
CA3106384A1 (fr) 2018-11-02 2020-05-07 Beijing Vdjbio Co., Ltd. Ctla4 modifie et ses methodes d'utilisation
EP3881072A4 (fr) 2018-11-16 2022-11-09 President And Fellows Of Harvard College Molécules et procédés d'immunodétection améliorée de petites molécules, telles que l'histamine
CN111196851B (zh) 2018-11-20 2021-11-16 厦门万泰凯瑞生物技术有限公司 针对人抗缪勒管激素的特异性抗体及其应用
IL263184A (en) 2018-11-21 2020-05-31 Yarden Yosef Method of treating cancer and compositions for same
US12134657B2 (en) 2018-11-28 2024-11-05 Oregon Health & Science University Therapeutic factor XII antibody
US12441776B2 (en) 2018-11-30 2025-10-14 Eirgen Pharma Ltd. Oxyntomodulin peptide analog formulations
KR20210111254A (ko) 2018-11-30 2021-09-10 캐리스 엠피아이, 아이엔씨. 차세대 분자 프로파일링
US12478571B2 (en) 2018-12-17 2025-11-25 Pontis Biologics, Inc. Enzyme based compositions and methods for removing dental calculi
KR20210109520A (ko) 2018-12-28 2021-09-06 쓰촨 케룬-바이오테크 바이오파마수티컬 컴퍼니 리미티드 항체 및 이의 용도
IL285083B1 (en) 2019-01-23 2026-06-01 Yeda Res & Dev Medium for pluripotent stem cells
CN113454238B (zh) 2019-01-25 2025-02-11 哈佛大学校长及研究员协会 用于合成核酸的组合物和方法
WO2020159445A1 (fr) 2019-01-31 2020-08-06 Agency For Science, Technology And Research Inhibiteur cnx/erp57 destiné à être utilisé dans le traitement ou la prévention du cancer
IL264768A (en) 2019-02-10 2020-08-31 Sagi Irit Anti-matrix metalloproteinase 7 (mmp-7) inhibitory antibody and uses thereof
IL264854A (en) 2019-02-14 2020-08-31 Bahat Anat Spt5 inhibitors and methods of use thereof
CN114555825A (zh) 2019-02-15 2022-05-27 领先细胞医疗诊断有限公司 用于通过原位杂交进行核酸的多路复用检测的方法
EP3927378A1 (fr) 2019-02-21 2021-12-29 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Procédé de réduction d'une néphrotoxicité induite par des médicaments
EP3927807A1 (fr) 2019-02-21 2021-12-29 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Procédés de génération d'organoïdes pour criblage à haut rendement de médicaments
MX2021010611A (es) 2019-03-05 2021-11-12 The State Of Israel Ministry Of Agriculture & Rural Development Agricultural Res Organization Aro Vo Aves con genoma editado.
CA3133074A1 (fr) 2019-03-11 2020-09-17 Memorial Sloan Kettering Cancer Center Anticorps cd22 et leurs procedes d'utilisation
GB201903521D0 (en) 2019-03-14 2019-05-01 Tropic Biosciences Uk Ltd No title
GB201903520D0 (en) 2019-03-14 2019-05-01 Tropic Biosciences Uk Ltd Modifying the specificity of non-coding rna molecules for silencing genes in eukaryotic cells
GB201903519D0 (en) 2019-03-14 2019-05-01 Tropic Biosciences Uk Ltd Introducing silencing activity to dysfunctional rna molecules and modifying their specificity against a gene of interest
IL265486A (en) 2019-03-19 2020-09-30 Yeda Res & Dev Type II stable opsins and methods of using them
WO2020194317A1 (fr) 2019-03-28 2020-10-01 Yeda Research And Development Co. Ltd. Méthode de traitement de troubles liés aux lipides
WO2020202142A2 (fr) 2019-03-31 2020-10-08 Yeda Research And Development Co. Ltd. Composés anti-viraux et anti-tumoraux
EP3957652A4 (fr) 2019-04-16 2023-06-21 Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. Anticorps anti-fxi/fxia et son utilisation
CA3138566A1 (fr) 2019-04-30 2020-11-05 Larimar Therapeutics, Inc. Marqueurs sensibles a la frataxine pour determiner l'efficacite d'une therapie de remplacement de frataxine
IL266433B (en) 2019-05-02 2020-11-30 Sagi Irit Preparations containing the propeptide of lysyl oxidase and their uses
EP3969619A1 (fr) 2019-05-13 2022-03-23 Yeda Research and Development Co. Ltd Biomarqueurs de micro-adn acellulaire pour le pronostic et le diagnostic de maladies neurodégénératives
IL266728B (en) 2019-05-19 2020-11-30 Yeda Res & Dev Identification of recurrent mutant neopeptides
US12467038B2 (en) 2019-05-22 2025-11-11 Hadasit Medical Research Services And Development Ltd. Methods of culturing human pluripotent cells
IT201900007222A1 (it) 2019-05-24 2020-11-24 Univ Degli Studi Di Torino Composizione di liposomi e metodo di dosaggio basato sull'uso degli stessi
WO2020237491A1 (fr) 2019-05-28 2020-12-03 Shanghaitech University Composition et méthodes pour le traitement d'une dysplasie ectodermique 2, type clouston
JP7668233B2 (ja) 2019-06-12 2025-04-24 ハダシット メディカル リサーチ サービシーズ アンド ディベロップメント リミテッド オリゴデンドロサイトの産生方法
US12516313B2 (en) 2019-06-16 2026-01-06 Yeda Research And Development Co. Ltd. Method for stabilizing intracellular RNA
US12509512B2 (en) 2019-06-27 2025-12-30 Ramot At Tel-Aviv University Ltd. Semaphorin 3A antibodies and uses thereof
AU2020302791A1 (en) 2019-06-27 2022-02-03 Dovetail Genomics, Llc Methods and compositions for proximity ligation
EP3994268A1 (fr) 2019-07-04 2022-05-11 Ukko Inc. Alpha gliadine sans épitope et son utilisation pour la gestion de la maladie coeliaque et de la sensibilité au gluten
BR112022000319A2 (pt) 2019-07-11 2022-03-15 Kahr Medical Ltd Heterodímeros e métodos de uso dos mesmos
IL268111A (en) 2019-07-16 2021-01-31 Fainzilber Michael Methods of treating pain
US12668621B2 (en) 2019-07-16 2026-06-30 Ramot At Tel-Aviv University Ltd. Compositions and methods for the treatment of tuberculosis
JP2022541538A (ja) 2019-07-19 2022-09-26 ザ・チルドレンズ・ホスピタル・オブ・フィラデルフィア グリピカン２結合ドメインを含有するキメラ抗原受容体
EP4004037A1 (fr) 2019-07-26 2022-06-01 Vanderbilt University Anticorps monoclonaux humains dirigés contre l'entérovirus d68
EP4004548B1 (fr) 2019-07-29 2026-01-14 Yeda Research and Development Co. Ltd Procédés de traitement et de diagnostic du cancer du poumon
CA3148950A1 (fr) 2019-07-30 2021-02-04 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (A.R.O.), Volcani Center Methodes de regulation de la synthese de cannabinoides chez la plante ou dans des cellules et plantes et cellules ainsi produites
WO2021028909A1 (fr) 2019-08-12 2021-02-18 Yeda Research And Development Co. Ltd. Test sanguin de réparation de l'adn pour prédire la réponse de patients atteints d'un cancer du poumon à une immunothérapie
JP2022545265A (ja) 2019-08-20 2022-10-26 ニューリタス リミテッド 筋萎縮を治療するためのペプチド
EP3783012A1 (fr) 2019-08-20 2021-02-24 Nuritas Limited Peptide antimicrobien
US20240140988A1 (en) 2019-08-22 2024-05-02 Ariel Scientific Innovations Ltd. Scaled-up methods for purifying antibodies
IL268965A (en) 2019-08-27 2021-02-28 Yeda Research And Development Co Ltd Treatment of bacteriel vaginosis
CN114929743B (zh) 2019-09-05 2026-01-02 纪念斯隆凯特琳癌症中心 抗steap1抗体及其用途
WO2021048852A1 (fr) 2019-09-11 2021-03-18 Yeda Research And Development Co. Ltd. Méthodes de traitement du cancer du sein
EP4031118B1 (fr) 2019-09-16 2026-01-28 The Children's Hospital of Philadelphia Analogue de mithramycine pour le traitement de tumeurs mutantes swi-snf
JP2023501871A (ja) 2019-09-20 2023-01-20 上海吉倍生物技術有限公司 Ｂｃｍａ標的化抗体及びキメラ抗原受容体
IL269674B (en) 2019-09-25 2020-08-31 Roy Bar Ziv Assembling protein complexes on a chip
KR20220088428A (ko) 2019-09-26 2022-06-27 주식회사 에스티큐브앤컴퍼니 글리코실화된 ctla-4에 대해 특이적인 항체 및 이의 사용 방법
CN114206931B (zh) 2019-09-30 2024-06-04 四川科伦博泰生物医药股份有限公司 抗pd-1抗体及其用途
KR20220082007A (ko) 2019-10-08 2022-06-16 넥틴 테라퓨틱스 리미티드 폴리오바이러스 수용체(pvr)에 대한 항체 및 이의 용도
KR20220088438A (ko) 2019-10-09 2022-06-27 주식회사 에스티큐브앤컴퍼니 글리코실화된 lag3에 대해 특이적인 항체 및 이의 사용 방법
US12590950B2 (en) 2019-10-11 2026-03-31 University Of Massachusetts Methods for predicting ER-mediated DNA damage
MX2022004872A (es) 2019-10-22 2022-05-13 Nuritas Ltd Tratamiento de enfermedad de higado graso no alcoholico.
IL270306A (en) 2019-10-30 2021-05-31 Yeda Res & Dev Prevention and treatment of pre-myeloid and myeloid malignancies
US12692519B2 (en) 2019-10-31 2026-07-28 Yeda Research And Development Co. Ltd. Engineered autotrophic bacteria for CO2 conversion to organic materials
CA3160506A1 (fr) 2019-11-11 2021-05-20 Ibi-Ag Innovative Bio Insecticides Ltd. Nanocorps de lutte contre les insectes et leurs utilisations
US12385054B2 (en) 2019-11-19 2025-08-12 Protalix Ltd. Removal of constructs from transformed cells
IL270800A (en) 2019-11-20 2021-05-31 Yeda Res & Dev Method of treating alzheimer’s disease
US10792360B1 (en) 2019-11-21 2020-10-06 Chemocentryx, Inc. Compositions and methods for treating inflammatory bowel disease using CCR9 inhibitor and anti-TNF-alpha blocking antibodies
IL293489A (en) 2019-12-02 2022-08-01 Caris Mpi Inc predictor of pan-cancer platinum response
CN115176027A (zh) 2019-12-12 2022-10-11 哈佛大学校长及研究员协会 用于光指导的生物分子条形码化的组合物和方法
EP4047019A4 (fr) 2019-12-13 2023-11-15 Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. Anticorps anti-tslp et utilisations de celui-ci
CA3164996A1 (fr) 2019-12-20 2021-06-14 Novarock Biotherapeutics, Ltd. Anticorps anti-interleukine-23 p19 et leurs methodes d'utilisation
EP4077731A1 (fr) 2019-12-22 2022-10-26 Yeda Research and Development Co. Ltd Diagnostic de la démence frontotemporale
IL271656A (en) 2019-12-22 2021-06-30 Yeda Res & Dev System and methods for identifying cells that have undergone genome editing
EP3842452A1 (fr) 2019-12-26 2021-06-30 Universitat Autònoma de Barcelona Protéines d'échafaudage et nanoconjugués thérapeutiques à base de nidogène
IL271778A (en) 2019-12-31 2021-06-30 Ichilov Tech Ltd Methods for treating atopic dermatitis
US20230048719A1 (en) 2019-12-31 2023-02-16 Kahr Medical Ltd. Methods of culturing t cells with a 4-1bbl fusion polypeptide and uses of same
US20230048361A1 (en) 2019-12-31 2023-02-16 Kahr Medical Ltd. Methods of culturing t cells and uses of same
CN113061165B (zh) 2020-01-02 2026-04-21 厦门大学 EB病毒BNLF2b基因编码多肽及其检测用途
US12667570B2 (en) 2020-01-08 2026-06-30 Icahn School Of Medicine At Mount Sinai Small molecule modulators of KSR-bound MEK
IL272074B2 (en) 2020-01-15 2024-12-01 Immunity Pharma Ltd Peptide compounds and methods of treating diseases using same
KR20220145339A (ko) 2020-01-22 2022-10-28 라모트 앳 텔-아비브 유니버시티 리미티드 항-ide 항체 및 이의 용도
IL272194A (en) 2020-01-22 2021-07-29 Yeda Res & Dev Multispecific antibodies for use in treating diseases
WO2021152584A1 (fr) 2020-01-28 2021-08-05 Ariel Scientific Innovations Ltd. Procédés d'analyse de membranes cellulaires
WO2021152595A1 (fr) 2020-01-29 2021-08-05 Memed Diagnostics Ltd. Méthodes de diagnostic et de classification d'infections virales
EP4096647A1 (fr) 2020-01-30 2022-12-07 Yeda Research and Development Co. Ltd Traitement d'une maladie hépatique aiguë à l'aide d'inhibiteurs de tlr-mik
IL272389A (en) 2020-01-30 2021-08-31 Yeda Res & Dev Kits containing antibodies to PD-L1 and their uses in therapy
WO2021152586A1 (fr) 2020-01-30 2021-08-05 Yeda Research And Development Co. Ltd. Procédés d'analyse du microbiome, du profil d'immunoglobuline et de l'état physiologique
IL272390A (en) 2020-01-30 2021-08-31 Yeda Res & Dev Cancer treatment methods
BR102020002165A2 (pt) 2020-01-31 2021-11-30 Fundação Oswaldo Cruz Anticorpo, seu uso, composição farmacêutica o compreendendo, método de diagnóstico de infecções fúngicas, kit de diagnóstico de infecções fúngicas e método para tratamento de infecções fúngicas.
WO2021156490A2 (fr) 2020-02-06 2021-08-12 Vib Vzw Liants du coronavirus
EP3862014A1 (fr) 2020-02-07 2021-08-11 Nuritas Limited Traitement de maladies associées au panx1
CA3170374A1 (fr) 2020-02-09 2021-08-12 Nlc Pharma Ltd Test de detection rapide du sras-cov-2
IL272586A (en) 2020-02-10 2021-08-31 Yeda Res & Dev A method for cell cluster analysis
KR20220140568A (ko) 2020-02-11 2022-10-18 벤더르빌트 유니버시티 중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2)에 대한 인간 단일클론 항체
WO2021167908A1 (fr) 2020-02-17 2021-08-26 Board Of Regents, The University Of Texas System Procédés d'expansion de lymphocytes infiltrant les tumeurs et leur utilisation
CA3173090A1 (fr) 2020-02-25 2021-09-02 Vib Vzw Modulateurs allosteriques de la kinase a repetitions riches en leucines 2
EP4110823A1 (fr) 2020-02-26 2023-01-04 A2 Biotherapeutics, Inc. Polypeptides ciblant des complexes mage-a3 peptide-mhc et leurs méthodes d'utilisation
EP4121441A1 (fr) 2020-03-16 2023-01-25 Yeda Research and Development Co. Ltd Analogues peptidiques et leur utilisation dans le traitement de maladies, troubles ou états associés à une protéine p53 mutante
JP7709981B2 (ja) 2020-03-17 2025-07-17 ジェネヴァント サイエンシズ ゲーエムベーハー 肝星細胞への治療薬の脂質ナノ粒子送達のためのカチオン性脂質
WO2021195418A1 (fr) 2020-03-26 2021-09-30 Vanderbilt University Anticorps monoclonaux humains dirigés contre le coronavirus 2 du syndrome respiratoire aigu sévère (sars-cov-2)
WO2021195385A1 (fr) 2020-03-26 2021-09-30 Vanderbilt University Anticorps monoclonaux humains dirigés contre le coronavirus du syndrome respiratoire aigu sévère 2 (sras-cov-2)
WO2021199039A1 (fr) 2020-03-29 2021-10-07 Yeda Research And Development Co. Ltd. Variants de bêta-glucocérébrosidase destinés à être utilisés dans le traitement de la maladie de gaucher
CA3175870A1 (fr) 2020-03-31 2021-10-07 Biomuse Ltd. Bacteries destinees a la prevention et au traitement de lesions pulmonaires induites par la fumee
TWI904146B (zh) 2020-03-31 2025-11-11 美商卡默森屈有限公司 使用ｃｃｒ９抑制劑及抗ｉｌ-２３阻斷抗體治療發炎性腸道疾病的組成物及方法
EP4133107A1 (fr) 2020-04-06 2023-02-15 Yeda Research and Development Co. Ltd Méthodes de diagnostic du cancer et de prédiction de la réactivité à une thérapie
WO2021205459A1 (fr) 2020-04-07 2021-10-14 Ramot At Tel-Aviv University Ltd. Compositions contenant du cannabidiol et leurs utilisations
WO2021207062A1 (fr) 2020-04-07 2021-10-14 Advanced Cell Diagnostics, Inc. Procédé de détection d'acides nucléiques cibles par hybridation in situ , et kit associé
US20230135456A1 (en) 2020-04-13 2023-05-04 Exoprother Medical Ltd. Cell-derived vesicles comprising wild-type p53 protein for antiviral therapy
US20210322483A1 (en) 2020-04-16 2021-10-21 Ichilov Tech Ltd. Cell-derived particles presenting heterologous cd24 and use thereof in therapy
CA3176545A1 (fr) 2020-04-22 2021-10-28 President And Fellows Of Harvard College Procedes isothermes, compositions, kits et systemes de detection d'acides nucleiques
EP4149512A4 (fr) 2020-05-12 2024-06-05 Board of Regents, The University of Texas System Procédés de traitement du glioblastome
WO2021229577A1 (fr) 2020-05-12 2021-11-18 Collplant Ltd. Collagène utilisé comme outil d'administration d'agents antiviraux à base de métaux
CR20220580A (es) 2020-05-15 2023-04-11 Sichuan Kelun Biotech Biopharmaceutical Co Ltd Conjugado anticuerpo-fármaco, método de preparación del mismo y uso del mismo
IL274811B (en) 2020-05-20 2021-05-31 Yeda Res & Dev Spatial information is developed for the analysis of individual cells
CN115803062B (zh) 2020-06-03 2025-09-09 博泰康医药公司 滋养层细胞表面抗原2(trop-2)抗体
EP4521115A3 (fr) 2020-06-10 2025-06-11 Ramot at Tel-Aviv University Ltd. Procédés de détection de cpg méthylé
WO2021260696A1 (fr) 2020-06-22 2021-12-30 Ramot At Tel-Aviv University Ltd. Modules de protéine à sous-unités multiples, cellules exprimant ceux-ci et leurs utilisations
US20230293530A1 (en) 2020-06-24 2023-09-21 Yeda Research And Development Co. Ltd. Agents for sensitizing solid tumors to treatment
EP3939999A1 (fr) 2020-07-14 2022-01-19 Fundación del Sector Público Estatal Centro Nacional de Investigaciones Oncológicas Carlos III (F.S.P. CNIO) Anticorps neutralisant la sous-unité alpha du récepteur de l'interleukine 11 (il11ra) et leurs utilisations
IL276599A (en) 2020-08-09 2022-03-01 Yeda Res & Dev T cell receptor unique to mage-a1 and its uses
IL276627A (en) 2020-08-10 2022-03-01 Yeda Res & Dev Compositions for diagnosis and treatment of coronavirus infections
US20230309480A1 (en) 2020-08-18 2023-10-05 International Rice Research Institute Methods of increasing outcrossing rates in gramineae
EP4228656A4 (fr) 2020-08-18 2024-09-04 Yeda Research and Development Co. Ltd Composés anti-viraux et anti-tumoraux
WO2022040455A1 (fr) 2020-08-21 2022-02-24 Advanced Cell Diagnostics, Inc. Compositions et procédés pour déterminer une clonalité de lymphocytes t
WO2022047359A1 (fr) 2020-08-31 2022-03-03 Berg Llc Biomarqueurs protéiques du cancer du pancréas
KR20230060509A (ko) 2020-09-04 2023-05-04 노바록 바이오테라퓨틱스 리미티드 넥틴-4 항체 및 이의 용도
IL277488A (en) 2020-09-21 2022-04-01 Yeda Res & Dev Weight regulation method
EP4217370A2 (fr) 2020-09-23 2023-08-02 Yeda Research and Development Co. Ltd Méthodes et compositions pour traiter des infections à coronavirus
IL277743A (en) 2020-10-01 2022-04-01 Yeda Res & Dev A method for diagnosing breast cancer
JP2023545999A (ja) 2020-10-05 2023-11-01 プロタリクス リミテッド ダイサー（ｄｉｃｅｒ）様ノックアウト植物細胞
EP4225903A1 (fr) 2020-10-07 2023-08-16 Protalix Ltd. Dnase à action prolongée
IL320367A (en) 2020-10-09 2025-06-01 Univ Texas Prefusion-stabilized hmpv f proteins
WO2022079719A1 (fr) 2020-10-15 2022-04-21 Yeda Research And Development Co. Ltd. Méthode de traitement des cancers myéloïdes
IL278401A (en) 2020-10-29 2022-05-01 Yeda Res & Dev Polynucleotides for editing RNA and a method for using them
WO2022097157A2 (fr) 2020-11-09 2022-05-12 1E Therapeutics, Ltd. Méthodes de traitement ou de prévention d'infections bactériennes faisant appel à une séquence catalytique
GB202105804D0 (en) 2020-11-20 2021-06-09 Univ Cape Town Use of microvirin in the identification of mycobacterium tuberculosis mannose-capped lipoarabinomannan
JP2023550979A (ja) 2020-11-26 2023-12-06 ウッコ インコーポレイテッド 改変された高分子量グルテニンサブユニット及びその使用
EP4255451A4 (fr) 2020-12-03 2025-01-01 The Board Of Regents Of The University Of Texas System Méthodes d'identification d'anticorps bloquant lilrb
US20240003912A1 (en) 2020-12-04 2024-01-04 University Of Tennessee Research Foundation Method for diagnosing amyloid diseases
IL279559A (en) 2020-12-17 2022-07-01 Yeda Res & Dev Controlling ubiquitination of mlkl for treatment of disease
AU2021403156A1 (en) 2020-12-18 2023-07-13 Genevant Sciences Gmbh Peg lipids and lipid nanoparticles
EP4267741A2 (fr) 2020-12-28 2023-11-01 1E Therapeutics, Ltd. Zones cibles de l'arnm p21 pour le silençage
AU2021416356B2 (en) 2020-12-28 2026-02-26 1E Therapeutics, Ltd. P21 mrna targeting dnazymes
TW202604963A (zh) 2020-12-31 2026-02-01 中國商諾納生物（蘇州）有限公司 人lifr抗原結合蛋白及其製備方法和應用
EP4274886A2 (fr) 2021-01-10 2023-11-15 Supermeat the Essence of Meat Ltd. Agrégats de cellules souches pluripotentes et microtissus obtenus à partir de ceux-ci pour l'industrie de la viande cultivée
US20240083843A1 (en) 2021-01-14 2024-03-14 Yeda Research And Development Co. Ltd. Methods of producing vitamin d
IL280340B (en) 2021-01-21 2022-04-01 Yeda Res & Dev Antibodies, peptides and combinations of same for the treatment or prevention of coronavirus infection
US20240101717A1 (en) 2021-01-22 2024-03-28 Bionecure Therapeutics, Inc. Anti-her-2/trop-2 constructs and uses thereof
GB2603166A (en) 2021-01-29 2022-08-03 Thelper As Therapeutic and Diagnostic Agents and Uses Thereof
CN120093941A (zh) 2021-02-09 2025-06-06 苏州宜联生物医药有限公司 生物活性物偶联物及其制备方法和用途
IL305315A (en) 2021-02-18 2023-10-01 Yeda res & development co ltd Methods for producing vaccines
EP4294429A1 (fr) 2021-02-18 2023-12-27 Yeda Research and Development Co. Ltd Bactéries génétiquement modifiées pour générer des vaccins
US20250263490A1 (en) 2021-02-19 2025-08-21 Vib Vzw Cation-Independent Mannose-6-Phosphate Receptor Binders
US20240150455A1 (en) 2021-03-05 2024-05-09 Shanghai GenBase Biotechnology Co., Ltd. Anti-cldn6 antibody and use thereof
JP2024512392A (ja) 2021-03-08 2024-03-19 イミュノジェン・インコーポレーテッド がんの治療のためのａｄａｍ９を標的とする免疫抱合体の有効性を増加させるための方法
WO2022188652A1 (fr) 2021-03-09 2022-09-15 四川科伦博泰生物医药股份有限公司 Protéine de liaison à ror1 et son utilisation
IL281561A (en) 2021-03-16 2022-10-01 Yeda Res & Dev Methods and devices for ex-utero mouse embryonic development
CA3213068A1 (fr) 2021-03-25 2022-09-29 Ramot At Tel-Aviv University Ltd. Compositions et articles comprenant un polypeptide adnf
CA3213424A1 (fr) 2021-03-30 2022-10-06 Lior Moshe ZELCBUCH Bacteriophage de pseudomonas et ses utilisations
US20240402177A1 (en) 2021-04-06 2024-12-05 Bpgbio, Inc. Protein markers for estrogen receptor (er)-positive luminal a (la)-like and luminal b1 (lb1)-like breast cancer
CA3214821A1 (fr) 2021-04-06 2022-10-13 Guisong WANG Marqueurs proteiques pour le cancer du sein du type positif aux recepteurs des oestrogenes (er) et du type negatif aux recepteurs des oestrogenes (er)
WO2022216798A1 (fr) 2021-04-06 2022-10-13 Berg Llc Marqueurs protéiques pour le pronostic de la progression du cancer du sein
IL282188A (en) 2021-04-08 2022-11-01 Yeda Res & Dev Combined use of ketamine and bretigabine for the treatment of psychiatric disorders
WO2022219008A1 (fr) 2021-04-14 2022-10-20 University College Cork - National University Of Ireland, Cork Traitement d'événements cérébrovasculaires et de troubles neurologiques
CN117642176A (zh) 2021-04-14 2024-03-01 爱尔兰国立科克大学 Psg1用于治疗骨关节炎
US12626364B2 (en) 2021-04-16 2026-05-12 Advanced Cell Diagnostics, Inc. Materials and methods related to image processing
JP2024515726A (ja) 2021-04-19 2024-04-10 テンプル セラピューティクス ビーブイ 子宮内膜過剰増殖性障害および卵巣過剰増殖性障害を検出または処置するための方法
WO2022235765A2 (fr) 2021-05-04 2022-11-10 Inflammatix, Inc. Systèmes et procédés d'évaluation d'un état bactérien ou viral d'un échantillon
AU2022272135A1 (en) 2021-05-12 2024-01-04 Biomx Ltd. Staphylococcus bacteriophage and uses thereof
IL283563A (en) 2021-05-30 2022-12-01 Yeda Res & Dev Profiling of amps for the diagnosis, monitoring and treatment of microbiome-related diseases
US12704508B2 (en) 2021-06-02 2026-08-11 Alamar Biosciences, Inc. Nucleic acid linked immune-sandwich assay (NULISA)
CA3219233A1 (fr) 2021-06-06 2022-12-15 Ravid STRAUSSMAN Traitement combine du cancer
WO2022264132A1 (fr) 2021-06-13 2022-12-22 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Procédé de reprogrammation de cellules humaines
MX2023015233A (es) 2021-06-16 2024-01-31 Seedx Tech Inc Metodos de clasificacion de semillas de matthiola.
NL2028466B1 (en) 2021-06-16 2022-12-21 Sakata Holland B V Methods of sorting matthiola seeds
WO2023275255A1 (fr) 2021-07-02 2023-01-05 Tropic Biosciences UK Limited Retardement ou prévention du brunissement de bananes
EP4370134A4 (fr) 2021-07-13 2025-08-06 Technion Res & Dev Foundation Compositions et méthodes de traitement d'un état de santé
US20240382628A1 (en) 2021-07-15 2024-11-21 President And Fellows Of Harvard College Compositions and methods relating to cells with adhered particles
IL310226A (en) 2021-07-18 2024-03-01 Gamida Cell Ltd Therapeutic nk cell populations
WO2023002492A1 (fr) 2021-07-22 2023-01-26 Yeda Research And Development Co. Ltd. Optimisation de codon d'acides nucléiques
EP4377352A2 (fr) 2021-07-30 2024-06-05 Vib Vzw Liants du récepteur mannose-6-phosphate indépendants des cations pour la dégradation ciblée de protéines
EP4380973A2 (fr) 2021-08-02 2024-06-12 Yeda Research and Development Co. Ltd. Anticorps pour le traitement du cancer
EP4130028A1 (fr) 2021-08-03 2023-02-08 Rhazes Therapeutics Ltd Complexe tcr modifié et leurs procédés d'utilisation
CA3226947A1 (fr) 2021-08-03 2023-02-09 Muhammad YASSIN Complexe tcr modifie et ses procedes d'utilisation
CN118369418A (zh) 2021-08-10 2024-07-19 盖米达细胞有限公司 工程nk细胞、它们的生产方法及其用途
GB202112866D0 (en) 2021-09-09 2021-10-27 Tropic Biosciences Uk Ltd Resistance to fusarium wilt in a banana
GB202112865D0 (en) 2021-09-09 2021-10-27 Tropic Biosciences Uk Ltd Resistance to black sigatoka disease in banana
IL286430A (en) 2021-09-14 2023-04-01 Yeda Res & Dev Multispecific antibodies for use in the treatment of diseases
US20250084155A1 (en) 2021-09-29 2025-03-13 Board Of Regents, The University Of Texas System Anti-hsp70 antibodies and therapeutic uses thereof
EP4426821A1 (fr) 2021-11-02 2024-09-11 University of Massachusetts Protéines de fusion à domaine nme2cas9 incrusté
TW202440647A (zh) 2021-11-19 2024-10-16 英商米羅比奧有限公司 經工程改造之pd-1抗體及其用途
US11833503B2 (en) 2021-12-07 2023-12-05 Insilixa, Inc. Methods and compositions for surface functionalization of optical semiconductor-integrated biochips
WO2023105526A1 (fr) 2021-12-08 2023-06-15 Yeda Research And Development Co. Ltd. Cellules progénitrices pulmonaires multipotentes pour la régénération pulmonaire
KR20240137076A (ko) 2022-01-25 2024-09-19 메디링크 테라퓨틱스 (쑤저우) 컴퍼니, 리미티드 Her3에 대한 항체, 접합체 및 이의 용도
GB202201137D0 (en) 2022-01-28 2022-03-16 Thelper As Therapeutic and diagnostic agents and uses thereof
KR20240146674A (ko) 2022-01-31 2024-10-08 제네반트 사이언시즈 게엠베하 지질 나노입자를 위한 이온화 가능한 양이온성 지질
EP4238988A1 (fr) 2022-03-01 2023-09-06 Consejo Superior De Investigaciones Científicas Anticorps dirigés contre le sars-cov-2 et leurs utilisations
CN114853890B (zh) 2022-03-16 2023-04-28 沈阳三生制药有限责任公司 一种prlr抗原结合蛋白及其制备方法和应用
WO2023192976A1 (fr) 2022-04-01 2023-10-05 Board Of Regents, The University Of Texas System Anticorps à double spécificité dirigés contre pd-l1 et pd-l2 humains et leurs méthodes d'utilisation
GB202204813D0 (en) 2022-04-01 2022-05-18 Bradcode Ltd Human monoclonal antibodies and methods of use thereof
CA3247402A1 (fr) 2022-04-06 2023-10-12 Larimar Therapeutics, Inc. Marqueurs sensibles à la frataxine pour surveiller une thérapie de remplacement de frataxine
WO2023196866A1 (fr) 2022-04-06 2023-10-12 Mirobio Limited Anticorps cd200r modifiés et leurs utilisations
WO2023209708A1 (fr) 2022-04-25 2023-11-02 Yeda Research And Development Co. Ltd. Compositions pour modifier la signalisation de messager secondaire de l'adp-ribose cyclique
WO2023240201A1 (fr) 2022-06-08 2023-12-14 Larimar Therapeutics, Inc. Marqueurs sensibles à la frataxine pour surveiller la progression et le traitement du syndrome de leigh
KR20250030448A (ko) 2022-06-08 2025-03-05 온쿠레 인코포레이티드 Pi3k 억제제로서의 벤조피리미딘-4(3h)-온
WO2023239940A1 (fr) 2022-06-10 2023-12-14 Research Development Foundation Variants de fc igg1 sélectifs de fcriib modifiés et leurs utilisations
CA3259098A1 (fr) 2022-06-20 2025-04-18 Sichuan Huiyu Pharmaceutical Co., Ltd. Anticorps et son utilisation
CN119486763A (zh) 2022-07-14 2025-02-18 苏州宜联生物医药有限公司 抗体药物偶联物及其制备方法和用途
WO2024028794A1 (fr) 2022-08-02 2024-02-08 Temple Therapeutics BV Méthodes de traitement de troubles de l'endomètre et de l'hyperprolifération ovarienne
WO2024040020A1 (fr) 2022-08-15 2024-02-22 Absci Corporation Enrichissement de cellule spécifique à une activité d'affinité quantitative
WO2024038160A1 (fr) 2022-08-18 2024-02-22 Vib Vzw Moyens et méthodes pour moduler l'excitabilité neuronale
WO2024054469A1 (fr) 2022-09-08 2024-03-14 Onkure, Inc. Isoquinolones utilisés en tant qu'inhibiteurs de pi3k
WO2024064024A1 (fr) 2022-09-19 2024-03-28 Onkure, Inc. Dérivés de ((4-oxo-3,4-dihydroquinazolin-8-yl)méthyl)amine utilisés en tant qu'inhibiteurs de p13k pour le traitement du cancer
KR20250068694A (ko) 2022-09-20 2025-05-16 온쿠레 인코포레이티드 Mapk 경로 돌연변이로 인한 암의 치료를 위한 hdac 억제제 oki-179
US20260159606A1 (en) 2022-09-27 2026-06-11 Vib Vzw Antivirals Against Human Parainfluenza Virus
JP2025534040A (ja) 2022-10-14 2025-10-09 ユニバーシティ・カレッジ・コークーナショナル・ユニバーシティ・オブ・アイルランド，コーク 腱傷害の治療における使用のための胎盤発現タンパク質
WO2024081345A1 (fr) 2022-10-14 2024-04-18 Onkure, Inc. Benzopyrimidin-4(3h)-ones utilisées en tant qu'inhibiteurs de pi3k
EP4615490A2 (fr) 2022-11-11 2025-09-17 IGAN Biosciences Agents polypeptidiques de protéase iga
WO2024124041A1 (fr) 2022-12-07 2024-06-13 Advanced Cell Diagnostics, Inc. Détection multiplexée de cibles d'acides nucléiques
KR20250133660A (ko) 2023-01-09 2025-09-08 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 융합 전 안정화된 인간 파라인플루엔자 바이러스 3 f 단백질
WO2024178172A1 (fr) 2023-02-23 2024-08-29 University Of Rochester Agents et méthodes de production de molécules de fil d'adn à extrémités fermées
JP2026514097A (ja) 2023-04-11 2026-05-01 スターリング アイピー プライベート リミテッド 間質／がん細胞クロストーク及び／又は間質がもたらす治療への耐性の阻害
AU2024304180A1 (en) 2023-06-13 2026-01-08 Adcentrx Therapeutics, Inc. Methods and compositions related to antibodies and antibody drug conjugates (adcs) that bind nectin-4 proteins
EP4731656A1 (fr) 2023-06-23 2026-04-29 Vib Vzw Nouveaux liants ciblant le pathogène résistant aux médicaments multiples acinetobacter baumannii
KR20260068070A (ko) 2023-08-09 2026-05-13 시아먼 유니버시티 시트룰린화된 setdb1 폴리펩티드 및 이를 이용한 류마티스 관절염 진단
KR20260070403A (ko) 2023-08-11 2026-05-19 온쿠레 세러퓨틱스 인코포레이티드 Pi3k 억제제로서의 벤조피리디논 및 벤조피리미디논
WO2025052278A1 (fr) 2023-09-05 2025-03-13 Genevant Sciences Gmbh Lipides cationiques à base de pyrrolidine pour administration de nanoparticules lipidiques d'agents thérapeutiques à des cellules stellaires hépatiques
KR20260066110A (ko) 2023-09-07 2026-05-12 유니버시티 오브 테네시 리서치 파운데이션 아밀로이드 질환을 진단하는 방법
WO2025125577A1 (fr) 2023-12-14 2025-06-19 Vib Vzw Anticorps dirigés contre le virus de la grippe b
WO2025133951A1 (fr) 2023-12-21 2025-06-26 Genevant Sciences Gmbh Lipides ionisables appropriés pour des nanoparticules lipidiques
WO2025150045A1 (fr) 2024-01-12 2025-07-17 Gabriel Nussbaum Cibles bactériennes, agents thérapeutiques, compositions, kits et procédés d'utilisation dans le traitement et/ou la prévention du cancer
WO2025155991A2 (fr) 2024-01-19 2025-07-24 Bpgbio, Inc. Biomarqueurs prédictifs pour la réponse à un traitement par coenzyme q10 dans le cadre d'un cancer du pancréas
WO2025202871A1 (fr) 2024-03-27 2025-10-02 Pfizer Inc. Procédés d'identification de biomarqueurs de réponse à un traitement et leur utilisation avec un inhibiteur de cdk4
WO2025207755A1 (fr) 2024-03-29 2025-10-02 Onkure, Inc. Quinolizinones utilisés en tant qu'inhibiteurs de pi3k
WO2025212360A1 (fr) 2024-04-01 2025-10-09 Onkure, Inc. Isoquinolones en tant qu'inhibiteurs de pi3k
WO2025255233A1 (fr) 2024-06-07 2025-12-11 Onkure, Inc. Composés contenant des noyaux tricycliques fusionnés utilisés en tant qu'inhibiteurs de pi3k
WO2025264533A1 (fr) 2024-06-17 2025-12-26 Adcentrx Therapeutics Inc. Procédés et compositions associés à des conjugués anticorps-médicament (adcs) qui se lient à des protéines steap-1
WO2026006151A2 (fr) 2024-06-24 2026-01-02 University Of Rochester Fonctionnalisation d'ace-arnt codant pour des picovecteurs linéaires synthétiques
WO2026008665A1 (fr) 2024-07-01 2026-01-08 Vib Vzw Liants du complexe pd-1•pd-l1 et leur utilisation
WO2026019976A1 (fr) 2024-07-17 2026-01-22 The Broad Institute, Inc. Agent de réticulation covalent universel pour conjugués anticorps-oligo
US20260078179A1 (en) 2024-07-18 2026-03-19 Novarock Biotherapeutics, Ltd. Cdh17 antibodies and uses thereof
WO2026022677A1 (fr) 2024-07-22 2026-01-29 Genevant Sciences Gmbh Lipides cationiques chargés en permanence
WO2026022656A2 (fr) 2024-07-22 2026-01-29 Genevant Sciences Gmbh Formulations de particules lipidiques contenant des lipides cationiques chargés en permanence
WO2026044000A1 (fr) 2024-08-20 2026-02-26 Ethyreal Bio, Inc. Anticorps multispécifiques et leurs méthodes d'utilisation
WO2026044153A1 (fr) 2024-08-21 2026-02-26 Bpgbio, Inc. Utilisation de biomarqueurs dans le diagnostic du cancer du pancréas
WO2026058262A1 (fr) 2024-09-16 2026-03-19 Esther Priel Composés dérivés de tri-phényle substitués, compositions les comprenant et applications de ceux-ci
WO2026083241A1 (fr) 2024-10-15 2026-04-23 Genevant Sciences Gmbh Lipides ionisables comprenant des esters d'hydroxylamine n,n-substitués
WO2026112125A1 (fr) 2024-11-22 2026-05-28 Onkure, Inc. Benzopyridinones en tant qu'inhibiteurs de pi3k
WO2026122515A1 (fr) 2024-12-06 2026-06-11 Onkure, Inc. Quinolizinones en tant qu'inhibiteurs de pi3k

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3615222A (en) * 1968-09-04 1971-10-26 New England Nuclear Corp Method and apparatus for measuring the amount of a component in a biological fluid
US3654090A (en) * 1968-09-24 1972-04-04 Organon Method for the determination of antigens and antibodies

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DE2155658C3 (de) 1978-09-14
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DE2155658A1 (de) 1972-05-18
AU3508271A (en) 1973-05-03
DE2155658B2 (de) 1976-08-05
AU468060B2 (en) 1975-12-18
CA967464A (en) 1975-05-13
BR7107459D0 (pt) 1973-06-21
NL7016396A (fr) 1972-05-15
ZA717192B (en) 1972-08-30
SE451162B (sv) 1987-09-07
NL154598B (nl) 1977-09-15
DK140268B (da) 1979-07-16
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FI54033B (fi) 1978-05-31
US3850752A (en) 1974-11-26

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