IL115154A - Somatostatin peptides pharmaceutical compositions containing them and their use - Google Patents

Somatostatin peptides pharmaceutical compositions containing them and their use

Info

Publication number: IL115154A
Authority: IL; Israel
Prior art keywords: pharmaceutical compositions; compositions containing; somatostatin peptides; peptides pharmaceutical; somatostatin
Prior art date: 1994-09-06

Application number

IL11515495A

Other languages

English (en)

Other versions

IL115154A0 (en

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-09-06

Filing date

1995-09-04

Publication date

2000-08-13

1995-09-04 Application filed by Novartis Ag filed Critical Novartis Ag

1995-12-31 Publication of IL115154A0 publication Critical patent/IL115154A0/xx

2000-08-13 Publication of IL115154A publication Critical patent/IL115154A/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/083—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being octreotide or a somatostatin-receptor-binding peptide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
- C07K14/6555—Somatostatins at least 1 amino acid in D-form
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Optics & Photonics (AREA)
Physics & Mathematics (AREA)
Epidemiology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
General Chemical & Material Sciences (AREA)
Gastroenterology & Hepatology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Endocrinology (AREA)
Chemical Kinetics & Catalysis (AREA)
Toxicology (AREA)
Oncology (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

IL11515495A 1994-09-06 1995-09-04 Somatostatin peptides pharmaceutical compositions containing them and their use IL115154A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB9417873A GB9417873D0 (en)	1994-09-06	1994-09-06	Organic compounds

Publications (2)

Publication Number	Publication Date
IL115154A0 IL115154A0 (en)	1995-12-31
IL115154A true IL115154A (en)	2000-08-13

Family

ID=10760870

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL11515495A IL115154A (en)	1994-09-06	1995-09-04	Somatostatin peptides pharmaceutical compositions containing them and their use

Country Status (31)

Country	Link
US (2)	US6183721B1 (fr)
EP (1)	EP0714911B1 (fr)
JP (1)	JP3054346B2 (fr)
KR (1)	KR100364111B1 (fr)
CN (1)	CN1185252C (fr)
AT (1)	ATE199561T1 (fr)
AU (1)	AU703057B2 (fr)
BR (1)	BR9503936A (fr)
CA (1)	CA2157530C (fr)
CO (1)	CO4410344A1 (fr)
CZ (1)	CZ287012B6 (fr)
DE (1)	DE69520256T2 (fr)
DK (1)	DK0714911T3 (fr)
ES (1)	ES2157309T3 (fr)
FI (1)	FI117424B (fr)
GB (1)	GB9417873D0 (fr)
GR (1)	GR3035997T3 (fr)
HU (1)	HU218284B (fr)
IL (1)	IL115154A (fr)
NO (1)	NO316569B1 (fr)
NZ (1)	NZ272919A (fr)
PE (1)	PE41496A1 (fr)
PL (1)	PL182434B1 (fr)
PT (1)	PT714911E (fr)
RU (1)	RU2156774C2 (fr)
SG (1)	SG50356A1 (fr)
SI (1)	SI0714911T1 (fr)
SK (1)	SK283774B6 (fr)
TR (1)	TR199501094A2 (fr)
TW (1)	TW387898B (fr)
ZA (1)	ZA957475B (fr)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9417873D0 (en) *	1994-09-06	1994-10-26	Sandoz Ltd	Organic compounds
AT405906B (de) *	1997-03-14	1999-12-27	Irene Dr Virgolini	Radiomarkierte somatostatin rezeptor-liganden zur diagnose und therapie
US6358491B1 (en)	1999-08-27	2002-03-19	Berlex Laboratories, Inc.	Somatostatin analogs
MX368013B (es)	2001-02-19	2019-09-13	Novartis Ag	Tratamiento de cáncer.
CZ20032597A3 (cs) *	2001-02-26	2004-12-15	Bristol-Myers Squibb Pharma Company	Analogy kyseliny askorbové pro metaloradiofarmaceutika
BR0210915A (pt) *	2001-06-08	2004-06-08	Sod Conseils Rech Applic	Análogos quiméricos de somatostatina-dopamina
ITMI20011708A1 (it) *	2001-08-03	2003-02-03	Bracco Imaging Spa	Coniugati di peptidi, loro derivati con complessi metallici e utilizzo per i'indagine diagnostica tramite imaging per risonanza magnetica(m
UA81634C2 (ru)	2002-07-18	2008-01-25	Хеликс Биофарма Корп.	Фармацевтическая композиция уреазы для ингибирования роста раковых клеток и ее применение
CA2518406A1 (fr) *	2003-03-10	2004-09-23	Biogen Idec Ma Inc.	Fixation de medicament a mediation de thiol a des peptides de ciblage
US7632924B2 (en)	2004-06-18	2009-12-15	Ambrx, Inc.	Antigen-binding polypeptides and their uses
US20100029911A1 (en) *	2004-11-24	2010-02-04	Aplagen Gmbh	Method For Solid-Phase Peptide Synthesis And Purification
CA2699394C (fr)	2007-09-17	2020-03-24	The Regents Of The University Of California	Anticorps monoclonaux humains internalisants ciblant des cellules du cancer de la prostate in situ
CN105388287A (zh)	2011-03-11	2016-03-09	内布拉斯加大学董事委员会	冠状动脉疾病的生物标志物
US9480759B2 (en)	2012-11-21	2016-11-01	Serene, Llc	Tin-117m somatostatin receptor binding compounds and methods
CN103275189B (zh) *	2013-06-06	2014-08-06	深圳翰宇药业股份有限公司	一种用于肽树脂的裂解液及其在固相裂解合成生长抑素中的应用
EP3456700A1 (fr) *	2013-10-18	2019-03-20	Deutsches Krebsforschungszentrum	Inhibiteurs marqués de l'antigène membranaire spécifique de la prostate (psma), leur utilisation comme agents d'imagerie et agents pharmaceutiques pour le traitement du cancer de la prostate
SI3383920T1 (sl)	2015-11-30	2024-06-28	The Regents Of The University Of California	Dostava tumorsko specifičnega koristnega tovora in imunska aktivacija z uporabo humanega protitelesa, ki cilja visoko specifičen površinski antigen tumorskih celic
EP3503930B1 (fr)	2016-08-29	2024-12-11	Fred Hutchinson Cancer Center	Plate-forme de chélation pour l'administration de radionucléides
WO2018089829A1 (fr)	2016-11-10	2018-05-17	Fortis Therapeutics, Inc.	Cellules effectrices spécifiques de cd46 et leurs utilisations
HRP20231458T1 (hr)	2017-01-12	2024-05-10	Radiomedix Inc.	Liječenje stanica raka koje prekomjerno eksprimiraju receptore za somatostatin primjenom derivata oktreotida keliranih sa radioizotopima
TW202547563A (zh) *	2018-06-21	2025-12-16	德商愛利穆治療有限公司	用於放射性醫藥之含有體抑素類似物之組成物
TW202015744A (zh) *	2018-06-21	2020-05-01	法商艾普森藥品公司	用於放射性醫藥之含有體抑素類似物之組成物
US10596276B2 (en)	2018-07-25	2020-03-24	Advanced Accelerator Applications (Italy) S.R.L.	Stable, concentrated radionuclide complex solutions
US10596278B2 (en)	2018-07-25	2020-03-24	Advanced Accelerator Applications (Italy) S.R.L.	Stable, concentrated radionuclide complex solutions
CN114096264B (zh)	2019-05-20	2025-03-14	因多塞特股份有限公司	制备psma缀合物的方法
EP4192511A1 (fr)	2020-08-07	2023-06-14	Fortis Therapeutics, Inc.	Immunoconjugués ciblant cd46 et procédés d'utilisation associés
CN121793988A (zh)	2023-09-13	2026-04-03	东丽株式会社	癌的治疗、预防和/或诊断用药物组合物

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4725577A (en) *	1985-04-25	1988-02-16	Administrators Of The Tulane Educational Fund	Biologically active lysine containing octapeptides
US5006643A (en)	1987-06-24	1991-04-09	The Dow Chemical Company	Process for preparing isothiocyanato functionalized metal complexes
DE3728600A1 (de)	1987-08-27	1989-03-09	Hoechst Ag	Verfahren zur markierung von substanzen mit technetium oder rhenium
JPH0720989B2 (ja) *	1988-05-25	1995-03-08	アメリカ合衆国	大環状キレート化合物の抱合体と診断的テスト方法
GB9111199D0 (en) *	1991-05-23	1991-07-17	Sandoz Ltd	Improvements in or relating to organic compounds
MY106120A (en) *	1988-12-05	1995-03-31	Novartis Ag	Peptide derivatives.
ATE136224T1 (de)	1989-09-29	1996-04-15	Neorx Corp	Reduktion der nichtzielspezifischen retention von immunokonjugaten und ihren metaboliten
CA2131315A1 (fr) *	1992-03-25	1993-09-30	Geert J. Ensing	Methode peroperatoire de detection et de localisation des tissus tumoraux
NO940080L (no) *	1993-01-12	1994-07-13	Sandoz Ag	Polypeptider , fremgangsmåte for deres fremstilling og farmasöytiske preparater derav
US5650134A (en) *	1993-01-12	1997-07-22	Novartis Ag (Formerly Sandoz Ltd.)	Peptides
CA2179990A1 (fr) *	1994-01-12	1995-07-20	Gary Robert Bower	Agents biologiques de ciblage
GB9417873D0 (en) *	1994-09-06	1994-10-26	Sandoz Ltd	Organic compounds

1994
- 1994-09-06 GB GB9417873A patent/GB9417873D0/en active Pending
1995
- 1995-09-04 PT PT95810545T patent/PT714911E/pt unknown
- 1995-09-04 DK DK95810545T patent/DK0714911T3/da active
- 1995-09-04 RU RU95114740/04A patent/RU2156774C2/ru active
- 1995-09-04 AT AT95810545T patent/ATE199561T1/de active
- 1995-09-04 DE DE69520256T patent/DE69520256T2/de not_active Expired - Lifetime
- 1995-09-04 ES ES95810545T patent/ES2157309T3/es not_active Expired - Lifetime
- 1995-09-04 HU HU9502577A patent/HU218284B/hu unknown
- 1995-09-04 EP EP95810545A patent/EP0714911B1/fr not_active Expired - Lifetime
- 1995-09-04 SK SK1088-95A patent/SK283774B6/sk not_active IP Right Cessation
- 1995-09-04 IL IL11515495A patent/IL115154A/xx not_active IP Right Cessation
- 1995-09-04 SI SI9530491T patent/SI0714911T1/xx unknown
- 1995-09-04 FI FI954147A patent/FI117424B/fi not_active IP Right Cessation
- 1995-09-04 NO NO953457A patent/NO316569B1/no not_active IP Right Cessation
- 1995-09-04 CZ CZ19952263A patent/CZ287012B6/cs not_active IP Right Cessation
- 1995-09-04 PL PL95310274A patent/PL182434B1/pl unknown
- 1995-09-04 PE PE1995277844A patent/PE41496A1/es not_active IP Right Cessation
- 1995-09-04 NZ NZ272919A patent/NZ272919A/en not_active IP Right Cessation
- 1995-09-04 AU AU30414/95A patent/AU703057B2/en not_active Expired
- 1995-09-04 SG SG1995001282A patent/SG50356A1/en unknown
- 1995-09-05 BR BR9503936-8A patent/BR9503936A/pt not_active IP Right Cessation
- 1995-09-05 CO CO95040393A patent/CO4410344A1/es unknown
- 1995-09-05 CA CA002157530A patent/CA2157530C/fr not_active Expired - Lifetime
- 1995-09-05 JP JP7227906A patent/JP3054346B2/ja not_active Expired - Lifetime
- 1995-09-05 CN CNB951156101A patent/CN1185252C/zh not_active Expired - Lifetime
- 1995-09-05 KR KR1019950028905A patent/KR100364111B1/ko not_active Expired - Lifetime
- 1995-09-06 TR TR95/01094A patent/TR199501094A2/xx unknown
- 1995-09-06 ZA ZA957475A patent/ZA957475B/xx unknown
- 1995-09-08 TW TW084109395A patent/TW387898B/zh not_active IP Right Cessation
1997
- 1997-04-23 US US08/842,125 patent/US6183721B1/en not_active Expired - Lifetime
2000
- 2000-07-05 US US09/609,844 patent/US6277356B1/en not_active Expired - Lifetime
2001
- 2001-06-06 GR GR20010400850T patent/GR3035997T3/el unknown

Also Published As

Publication number	Publication date
PL182434B1 (pl)	2002-01-31
ES2157309T3 (es)	2001-08-16
JPH0881498A (ja)	1996-03-26
AU3041495A (en)	1996-03-21
BR9503936A (pt)	1996-09-24
CZ287012B6 (en)	2000-08-16
PL310274A1 (en)	1996-03-18
SK108895A3 (en)	1996-06-05
SK283774B6 (sk)	2004-01-08
NO316569B1 (no)	2004-02-23
DE69520256T2 (de)	2001-08-09
GB9417873D0 (en)	1994-10-26
EP0714911A3 (fr)	1996-08-21
CN1127259A (zh)	1996-07-24
US6277356B1 (en)	2001-08-21
EP0714911B1 (fr)	2001-03-07
KR100364111B1 (ko)	2003-02-05
GR3035997T3 (en)	2001-09-28
HUT72895A (en)	1996-06-28
FI954147L (fi)	1996-03-07
HU218284B (en)	2000-07-28
IL115154A0 (en)	1995-12-31
NO953457D0 (no)	1995-09-04
DE69520256D1 (de)	2001-04-12
AU703057B2 (en)	1999-03-11
SI0714911T1 (en)	2001-08-31
PE41496A1 (es)	1996-10-14
RU2156774C2 (ru)	2000-09-27
SG50356A1 (en)	2000-11-21
TW387898B (en)	2000-04-21
KR960010683A (ko)	1996-04-20
ZA957475B (en)	1997-03-06
HU9502577D0 (en)	1995-11-28
US6183721B1 (en)	2001-02-06
NZ272919A (en)	1996-12-20
PT714911E (pt)	2001-08-30
EP0714911A2 (fr)	1996-06-05
FI117424B (fi)	2006-10-13
CA2157530A1 (fr)	1996-03-07
FI954147A0 (fi)	1995-09-04
JP3054346B2 (ja)	2000-06-19
ATE199561T1 (de)	2001-03-15
CN1185252C (zh)	2005-01-19
CA2157530C (fr)	2007-04-03
TR199501094A2 (tr)	1996-06-21
CO4410344A1 (es)	1997-01-09
DK0714911T3 (da)	2001-07-09
NO953457L (no)	1996-03-07
CZ226395A3 (en)	1996-03-13

Legal Events

Date	Code	Title
2000-12-06	FF	Patent granted
2001-06-14	KB	Patent renewed
2002-05-23	MM9K	Patent not in force due to non-payment of renewal fees
2013-08-29	KB	Patent renewed
2016-04-21	EXP	Patent expired

Publication	Publication Date	Title
IL115154A (en)	2000-08-13	Somatostatin peptides pharmaceutical compositions containing them and their use
PH22480A (en)	1988-09-12	New sulphonylaminoethyl compounds and pharmaceutical compositions containing these compounds
IL90067A0 (en)	1989-12-15	1alpha-hydroxyvitamin-d compounds and pharmaceutical compositions containing them
ZA864602B (en)	1988-02-24	2-arylimidazoles and pharmaceutical compositions containing these compounds
AU3778989A (en)	1989-11-29	Diaminedithiol chelating agents for radiopharmaceuticals
IL105717A0 (en)	1993-09-22	7beta substituted-4-aza-5alpha-cholestan-3-ones and pharmaceutical compositions containing them
PH25430A (en)	1991-07-01	Pharmaceutical compositions containing calcium salts
EP0186505A3 (en)	1989-02-15	Pharmaceutical compositions containing organogermanium compound and their use
NZ223200A (en)	1989-01-06	Anthelmintic compositions containing 2',5-dicloro-4'-nitrosalicylanilide and non aqueous carrier
GB9317297D0 (en)	1993-10-06	Biocidal compositions containing organoboron compounds
PL332964A1 (en)	1999-10-25	Bo-aromatic compound coupled ny intermediation of heteroethylene group and pharmaceutic and cosmetic containing such compounds
GB8814422D0 (en)	1988-07-20	Analgesic compounds & compositions
HUT50137A (en)	1989-12-28	Growth-controlling and herbicide compositions containing heterocyclic-substituted phenoxy-sulfonyl-urea i sposob poluchenija these compounds
HU9302821D0 (en)	1993-12-28	Pharmaceutical compositions containing 3-substituted-2-oxindole-1-carboxamide as medical agent
IL91482A0 (en)	1990-04-29	Pharmaceutical compositions containing certain heterocyclic compounds
ZA893517B (en)	1991-01-30	Peptide-drug compositions containing alpha-aminoboronic acid derivatives
SG92592G (en)	1992-12-04	Pharmaceutical compositions containing azanaphthalenes
IL91480A0 (en)	1990-04-29	Pharmaceutical compositions containing certain heterocyclic compounds
IL87444A0 (en)	1989-01-31	Pharmaceutical compositions containing polyaromatic compounds
IL91481A0 (en)	1990-04-29	Pharmaceutical compositions containing certain heterocyclic compounds
GB8812621D0 (en)	1988-06-29	Pharmaceutical composition containing combination of analgesic agents
GB8819137D0 (en)	1988-09-14	Therapeutic compounds compositions & uses thereof
GB9409833D0 (en)	1994-07-06	Compositions containing sunscreens
EP0193194A3 (en)	1987-09-02	15(r)-5-fluoroprostacyclins and pharmaceutical compositions containing said compounds
RO101093B1 (en)	1992-11-03	Dental protection composition