TR200001705T2 - ''İmidazonaftiridinler ve bunların sitokin biyosentezinin indüklenmesinde kullanılması'' - Google Patents

''İmidazonaftiridinler ve bunların sitokin biyosentezinin indüklenmesinde kullanılması''

Info

Publication number
TR200001705T2
TR200001705T2 TR2000/01705T TR200001705T TR200001705T2 TR 200001705 T2 TR200001705 T2 TR 200001705T2 TR 2000/01705 T TR2000/01705 T TR 2000/01705T TR 200001705 T TR200001705 T TR 200001705T TR 200001705 T2 TR200001705 T2 TR 200001705T2
Authority
TR
Turkey
Prior art keywords
imidazonaphthyridines
compounds
cytokine biosynthesis
inducing cytokine
preparing
Prior art date
Application number
TR2000/01705T
Other languages
English (en)
Inventor
J. Lindstrom Kyle
F.Gerster John
Original Assignee
Minnesota Mining And Manufacturing Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Minnesota Mining And Manufacturing Company filed Critical Minnesota Mining And Manufacturing Company
Publication of TR200001705T2 publication Critical patent/TR200001705T2/tr

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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
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    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
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Abstract

Imidazonaftiridin (1) ve tetrahidroimidazonaftiridin (II) bilesikleri interferon ve tümör nekroz faktörü gibi sitokinlerin biyosentezini indükler. Bilesikler antiviral ve antitümör özelliklei arzeder. Bilesiklerin hazirlanmasina, ve bilesiklerin hazirlanmasinda faydali olan ara maddelerin hazirlanmasina yönelik metodlar da tarif edilmektedir. R1 ve R2 ve A tarifnamede tayin edildigi gibidir.
TR2000/01705T 1997-12-11 1998-12-11 ''İmidazonaftiridinler ve bunların sitokin biyosentezinin indüklenmesinde kullanılması'' TR200001705T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6927697P 1997-12-11 1997-12-11

Publications (1)

Publication Number Publication Date
TR200001705T2 true TR200001705T2 (tr) 2001-07-23

Family

ID=22087889

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2000/01705T TR200001705T2 (tr) 1997-12-11 1998-12-11 ''İmidazonaftiridinler ve bunların sitokin biyosentezinin indüklenmesinde kullanılması''

Country Status (27)

Country Link
US (14) US6194425B1 (tr)
EP (1) EP1040112B1 (tr)
JP (4) JP4283438B2 (tr)
KR (3) KR100642702B1 (tr)
CN (1) CN1154647C (tr)
AT (3) ATE333456T1 (tr)
AU (1) AU753864B2 (tr)
BR (1) BR9814275A (tr)
CA (1) CA2311456C (tr)
CZ (1) CZ307184B6 (tr)
DE (3) DE69835844T2 (tr)
DK (1) DK1512686T3 (tr)
EE (1) EE04314B1 (tr)
ES (3) ES2270249T3 (tr)
HR (1) HRP20000363B1 (tr)
HU (1) HUP0101155A3 (tr)
IL (4) IL136556A0 (tr)
NO (3) NO316687B1 (tr)
NZ (1) NZ504776A (tr)
PL (1) PL193915B1 (tr)
PT (3) PT1040112E (tr)
RU (3) RU2221798C2 (tr)
SI (1) SI1512686T1 (tr)
SK (2) SK285872B6 (tr)
TR (1) TR200001705T2 (tr)
UA (1) UA67760C2 (tr)
WO (1) WO1999029693A1 (tr)

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