ATE98993T1 - Verfahren zur herstellung von proteinprodukten in aspergillus oryzae und in aspergillus zu verwendender promotor. - Google Patents

Verfahren zur herstellung von proteinprodukten in aspergillus oryzae und in aspergillus zu verwendender promotor.

Info

Publication number
ATE98993T1
ATE98993T1 AT87103806T AT87103806T ATE98993T1 AT E98993 T1 ATE98993 T1 AT E98993T1 AT 87103806 T AT87103806 T AT 87103806T AT 87103806 T AT87103806 T AT 87103806T AT E98993 T1 ATE98993 T1 AT E98993T1
Authority
AT
Austria
Prior art keywords
promoter
aspergillus
production
sequences
host
Prior art date
Application number
AT87103806T
Other languages
English (en)
Inventor
Esper Boel
Tove Christensen
Helle Fabricius Woeldike
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8102403&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE98993(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Application granted granted Critical
Publication of ATE98993T1 publication Critical patent/ATE98993T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C12N9/20—Triglyceride splitting, e.g. by means of lipase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C12N9/2411—Amylases
    • C12N9/2414—Alpha-amylase (3.2.1.1.)
    • C12N9/2417—Alpha-amylase (3.2.1.1.) from microbiological source
    • C12N9/242—Fungal source
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6478—Aspartic endopeptidases (3.4.23)
    • C12N9/6481—Pepsins (3.4.23.1; 3.4.23.2; 3.4.23.3)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT87103806T 1986-03-17 1987-03-16 Verfahren zur herstellung von proteinprodukten in aspergillus oryzae und in aspergillus zu verwendender promotor. ATE98993T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK122686A DK122686D0 (da) 1986-03-17 1986-03-17 Fremstilling af proteiner
EP87103806A EP0238023B2 (de) 1986-03-17 1987-03-16 Verfahren zur Herstellung von Proteinprodukten in Aspergillus Oryzae und in Aspergillus zu verwendender Promotor

Publications (1)

Publication Number Publication Date
ATE98993T1 true ATE98993T1 (de) 1994-01-15

Family

ID=8102403

Family Applications (2)

Application Number Title Priority Date Filing Date
AT92104421T ATE282093T1 (de) 1986-03-17 1987-03-16 Verfahren zur herstellung von proteinprodukten in aspergillus-oryzae und in aspergillus zu verwendender promotor
AT87103806T ATE98993T1 (de) 1986-03-17 1987-03-16 Verfahren zur herstellung von proteinprodukten in aspergillus oryzae und in aspergillus zu verwendender promotor.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT92104421T ATE282093T1 (de) 1986-03-17 1987-03-16 Verfahren zur herstellung von proteinprodukten in aspergillus-oryzae und in aspergillus zu verwendender promotor

Country Status (9)

Country Link
EP (3) EP0238023B2 (de)
JP (4) JPH0665316B2 (de)
AT (2) ATE282093T1 (de)
CA (1) CA1341593C (de)
DE (2) DE3752379T2 (de)
DK (1) DK122686D0 (de)
ES (1) ES2061446T5 (de)
FI (2) FI108147B (de)
IE (2) IE63169B1 (de)

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US6004785A (en) * 1985-08-29 1999-12-21 Genencor International Inc. Heterologous polypeptides expressed in filamentous fungi, processes for making same, and vectors for making same
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DE3752379D1 (de) 2004-12-16
EP0489718B1 (de) 2004-11-10
FI871144L (fi) 1987-09-18
EP0238023A2 (de) 1987-09-23
EP1502952A3 (de) 2005-05-11
EP0238023B1 (de) 1993-12-22
JP3005618B2 (ja) 2000-01-31
JPH0751067A (ja) 1995-02-28
EP0489718A1 (de) 1992-06-10
EP0238023A3 (en) 1989-02-22
IE63169B1 (en) 1995-03-22
DE3752379T2 (de) 2005-10-20
FI108147B (fi) 2001-11-30
FI871144A0 (fi) 1987-03-16
JPS62272988A (ja) 1987-11-27
IE870682L (en) 1987-09-17
JPH10276787A (ja) 1998-10-20
JP2003153696A (ja) 2003-05-27
JP3903165B2 (ja) 2007-04-11
FI112376B (fi) 2003-11-28
DE3788524D1 (de) 1994-02-03
EP0238023B2 (de) 2002-10-02
DK122686D0 (da) 1986-03-17
DE3788524T2 (de) 1994-05-11
EP1502952A2 (de) 2005-02-02
JPH0665316B2 (ja) 1994-08-24
CA1341593C (en) 2009-04-21
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ES2061446T3 (es) 1994-12-16
ATE282093T1 (de) 2004-11-15
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FI20011797L (fi) 2001-09-12
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