CL2017000888A1 - Moléculas de anticuerpo que se unen a pd-l1 y usos de las mismas - Google Patents

Moléculas de anticuerpo que se unen a pd-l1 y usos de las mismas

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Publication number
CL2017000888A1
CL2017000888A1 CL2017000888A CL2017000888A CL2017000888A1 CL 2017000888 A1 CL2017000888 A1 CL 2017000888A1 CL 2017000888 A CL2017000888 A CL 2017000888A CL 2017000888 A CL2017000888 A CL 2017000888A CL 2017000888 A1 CL2017000888 A1 CL 2017000888A1
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CL
Chile
Prior art keywords
antibody molecules
bind
affecting
disclosed
infectious
Prior art date
Application number
CL2017000888A
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English (en)
Inventor
Dranoff Glenn
Gordon Freeman James
Arlene Sharpe Helen
Gerhard Frey Johann
Hwai Chang Wen
Jennifer Mataraza Marie
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Novartis Ag
Harvard College
Dana Farber Cancer Inst Inc
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54347916&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2017000888(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag, Harvard College, Dana Farber Cancer Inst Inc filed Critical Novartis Ag
Publication of CL2017000888A1 publication Critical patent/CL2017000888A1/es

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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G01N33/5759—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds localised on the membrane of tumour or cancer cells
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    • C07K2317/00—Immunoglobulins specific features
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    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
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    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
    • G01N2333/70532—B7 molecules, e.g. CD80, CD86

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Abstract

<p>SE DIVULGAN MOLÉCULAS DE ANTICUERPO QUE SE UNEN ESPECÍFICAMENTE A PD-L1. TAMBIÉN SE DIVULGAN TERAPIAS DE COMBINACIÓN QUE COMPRENDEN MOLÉCULAS DE ANTICUERPO ANTI-PD-LI. LAS MOLÉCULAS DE ANTICUERPO ANTI-PD-LI SE PUEDEN USAR PARA TRATAR, PREVENIR Y/O DIAGNOSTICAR AFECCIONES Y TRASTORNOS CANCEROSOS O INFECCIOSOS.</p>
CL2017000888A 2014-10-14 2017-04-11 Moléculas de anticuerpo que se unen a pd-l1 y usos de las mismas CL2017000888A1 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201462063852P 2014-10-14 2014-10-14
US201462094847P 2014-12-19 2014-12-19
US201562198545P 2015-07-29 2015-07-29
US201562213076P 2015-09-01 2015-09-01

Publications (1)

Publication Number Publication Date
CL2017000888A1 true CL2017000888A1 (es) 2017-08-18

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ID=54347916

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CL2017000888A CL2017000888A1 (es) 2014-10-14 2017-04-11 Moléculas de anticuerpo que se unen a pd-l1 y usos de las mismas

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US (4) US9988452B2 (es)
EP (2) EP4245376A3 (es)
JP (3) JP6877339B2 (es)
KR (1) KR102513870B1 (es)
CN (2) CN114920840A (es)
AU (1) AU2015333687B2 (es)
CA (1) CA2964367C (es)
CL (1) CL2017000888A1 (es)
CO (1) CO2017003490A2 (es)
CR (1) CR20170143A (es)
CU (1) CU20170052A7 (es)
EA (1) EA201790834A1 (es)
EC (1) ECSP17029218A (es)
ES (1) ES2952717T3 (es)
GT (1) GT201700081A (es)
IL (1) IL251563B (es)
MA (1) MA40035A (es)
MX (1) MX389663B (es)
PE (1) PE20171067A1 (es)
PH (1) PH12017500692A1 (es)
SG (1) SG11201702401RA (es)
TN (1) TN2017000129A1 (es)
TW (1) TWI716362B (es)
UY (1) UY36351A (es)
WO (1) WO2016061142A1 (es)

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