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DE2636722A1
(de)
*
|
1976-08-14 |
1978-02-16 |
Goedecke Ag |
3-hydroxy-pyrrolinon-2-derivate
|
|
JPS57192573A
(en)
|
1981-05-25 |
1982-11-26 |
Hochiki Co |
Fire fighting agent
|
|
JPS6126111A
(ja)
|
1984-07-16 |
1986-02-05 |
Shin Meiwa Ind Co Ltd |
産業用ロボツト
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JPS6137764A
(ja)
|
1984-07-31 |
1986-02-22 |
Suntory Ltd |
抗プロリルエンドペプチダ−ゼ活性を有する新規生理活性化合物
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JPS6152021A
(ja)
|
1984-08-22 |
1986-03-14 |
Fujitsu Ltd |
スケルチ回路
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JPS6172439A
(ja)
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1984-09-18 |
1986-04-14 |
Sanyo Electric Co Ltd |
デ−タ転送方式
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EP0201743B1
(en)
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1985-04-16 |
1992-04-01 |
Suntory Limited |
Dipeptide derivatives of fatty acids, process for preparing them, pharmaceutical composition and use
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CA1309805C
(en)
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1985-04-16 |
1992-11-03 |
Naoki Higuchi |
Dipeptide derivative and synthesis and use thereof
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JPH0623190B2
(ja)
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1985-04-16 |
1994-03-30 |
サントリー株式会社 |
インヒビタ−活性を有するｎ−アシルピロリジン誘導体及びその製法並びに用途
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JPS62114957A
(ja)
|
1985-11-13 |
1987-05-26 |
Suntory Ltd |
プロリルエンドペプチダ−ゼ阻害作用を有する新規ピロリジン誘導体およびその製法並びに用途
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JPH0714878B2
(ja)
|
1985-11-14 |
1995-02-22 |
サントリー株式会社 |
ピロリジンアミドを有効成分とするプロリルエンドペプチダーゼ阻害剤
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JPH0764834B2
(ja)
|
1985-11-29 |
1995-07-12 |
サントリー株式会社 |
プロリルエンドペプチダーゼ阻害活性を有する新規ピロリジンアミド誘導体およびその製法並びに用途
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CA1320734C
(en)
|
1986-02-04 |
1993-07-27 |
Suntory Limited |
Pyrrolidineamide derivative of acylamino acid and pharmaceutical composition containing the same
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US5198458A
(en)
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1986-02-04 |
1993-03-30 |
Suntory Limited |
Pyrrolidineamide derivatives of acylamino acid and pharmaceutical composition containing the same
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JPH08806B2
(ja)
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1986-11-18 |
1996-01-10 |
サントリー株式会社 |
プロリルエンドペプチダ−ゼ阻害作用を有する新規ピロリジンアミド誘導体
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DE3786229T2
(de)
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1986-11-20 |
1993-10-07 |
Ono Pharmaceutical Co |
Prolinalderivate.
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US5254550A
(en)
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1986-11-20 |
1993-10-19 |
Ono Pharmaceutical Co., Ltd. |
Prolinal derivatives and pharmaceutical compositions thereof
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JPS63162672A
(ja)
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1986-12-25 |
1988-07-06 |
Ono Pharmaceut Co Ltd |
新規なプロリナ−ル誘導体、それらの製造方法およびそれらを含有する抗健忘症剤
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JPH089591B2
(ja)
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1986-12-29 |
1996-01-31 |
小野薬品工業株式会社 |
新規なプロリナール誘導体
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DE3783754T2
(de)
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1986-12-29 |
1993-08-05 |
Ono Pharmaceutical Co |
Prolin-derivate.
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US5262431A
(en)
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1986-12-29 |
1993-11-16 |
Ono Pharmaceutical Co., Ltd. |
Prolinal derivatives and pharmaceutical compositions thereof
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EP0277588B1
(en)
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1987-02-04 |
1993-03-24 |
Ono Pharmaceutical Co., Ltd. |
Prolinal derivatives
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DE3875361T2
(de)
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1987-02-23 |
1993-03-25 |
Ono Pharmaceutical Co |
Thiazolidin-derivate.
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JPS6442465A
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1987-08-07 |
1989-02-14 |
Wakunaga Pharma Co Ltd |
N-acylprolylpyrrolidine derivative, production and use thereof
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JP2649237B2
(ja)
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1988-03-07 |
1997-09-03 |
キッセイ薬品工業 株式会社 |
チアゾリジン誘導体
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US4857524A
(en)
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1987-08-08 |
1989-08-15 |
Kissei Pharmaceutical Co., Ltd. |
Thiazolidine compounds and therapeutic method
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JP2515558B2
(ja)
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1987-09-10 |
1996-07-10 |
株式会社ヤクルト本社 |
新規なペプチドおよびそれを有効成分とする抗健忘症剤
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JPH0742309B2
(ja)
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1987-11-30 |
1995-05-10 |
キッセイ薬品工業株式会社 |
チアゾリジン誘導体
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JPH01250370A
(ja)
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1987-12-23 |
1989-10-05 |
Zeria Pharmaceut Co Ltd |
新規アミノ酸イミド誘導体、製法ならびに用途
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US5053414A
(en)
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1988-04-08 |
1991-10-01 |
Ono Pharmaceutical Co., Ltd. |
Heterocyclic compounds
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(en)
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1988-07-15 |
1994-07-12 |
The Salk Institute For Biological Studies |
NPY peptide analogs
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ZA896376B
(en)
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1988-08-26 |
1990-05-30 |
Merrell Dow Pharma |
Neuropeptide y agonists
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ZA896374B
(en)
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1988-08-26 |
1990-05-30 |
Merrell Dow Pharma |
Neuropeptide y antagonists
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JP2531989B2
(ja)
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1988-09-14 |
1996-09-04 |
吉富製薬株式会社 |
ピリジン化合物
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CA2004028C
(en)
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1988-12-08 |
1998-09-22 |
Motoki Torizuka |
Condensed benzene derivative
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JPH02207070A
(ja)
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1989-02-07 |
1990-08-16 |
Zeria Pharmaceut Co Ltd |
アミノ酸イミド誘導体、それを含有する医薬及び該化合物の製造中間体
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EP0419683A4
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1989-04-13 |
1992-03-11 |
Japan Tobacco Inc. |
New amino acid derivatives having prolylendopeptidase inhibitor activity
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DE3939797A1
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1989-12-01 |
1991-06-06 |
Basf Ag |
Neue vom neuropeptid y abgeleitete peptide
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US4985560A
(en)
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1990-01-12 |
1991-01-15 |
American Home Products Corporation |
Pyridazino(4,5-b)indolizines
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JPH04211648A
(ja)
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1990-07-27 |
1992-08-03 |
Nippon Kayaku Co Ltd |
ケト酸アミド誘導体
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JPH03255080A
(ja)
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1990-03-05 |
1991-11-13 |
Yoshitomi Pharmaceut Ind Ltd |
ベンゼン化合物
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1990-03-22 |
1991-03-12 |
Bristol-Myers Squibb Co. |
BU-4164E - A and B, prolyl endopeptidase inhibitors
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1990-03-22 |
1991-12-17 |
Bristol-Myers Squibb Company |
BU-4164E - A and B, prolyl endopeptidase inhibitors and their methods of use
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JPH049367A
(ja)
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1990-04-26 |
1992-01-14 |
Zeria Pharmaceut Co Ltd |
アリールアルカノイル誘導体，該化合物の製造中間体及びそれらを含有する医薬
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FI925500A7
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1990-06-04 |
1992-12-03 |
Pfizer |
Aromaattisia pyrrolidiini- ja tiatsolidiiniamideja
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AU643300B2
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1990-06-07 |
1993-11-11 |
Zeria Pharmaceutical Co., Ltd. |
Novel arylalkanoylamine derivative and drug containing the same
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1990-07-27 |
1996-04-09 |
Yoshitomi Pharmaceutical Industries, Ltd. |
Proline derivatives possessing prolyl endopeptidase-inhibitory activity
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JPH05186498A
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1991-12-27 |
1993-07-27 |
Japan Tobacco Inc |
プロリン誘導体
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EP0468469A2
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1990-07-27 |
1992-01-29 |
Japan Tobacco Inc. |
Proline derivatives
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JPH04235162A
(ja)
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1990-08-09 |
1992-08-24 |
Zeria Pharmaceut Co Ltd |
新規コハク酸アミド誘導体およびそれを含有する医薬
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JPH04208299A
(ja)
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1990-11-30 |
1992-07-29 |
Ajinomoto Co Inc |
プロリルエンドペプチターゼ阻害ペプチド
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1991-05-01 |
1992-04-14 |
Mayo Foundation For Medical Education And Research |
Huperzine a analogs as acetylcholinesterase inhibitors
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1991-05-24 |
1993-01-08 |
Pharmavene, Inc. |
Treatment of drug withdrawal symptoms and drug craving with type b monoamine oxidase inhibitors
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1991-06-20 |
1995-09-12 |
Snow Brand Milk Products Co., Ltd. |
Prolyl endopeptidase inhibitors SNA-115 and SNA-115T, and process for the production and productive strain thereof
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JP3010795B2
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1991-07-04 |
2000-02-21 |
不二製油株式会社 |
ペプチドの苦味除去方法
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WO1993003034A1
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1991-07-29 |
1993-02-18 |
Warner-Lambert Company |
Quinazoline derivatives as acetylcholinesterase inhibitors
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JPH08501055A
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1991-12-19 |
1996-02-06 |
ガーヴァン インスティチュート オブ メディカル リサーチ |
神経ペプチドチロシンの生物学的機能を抑制する新規な分子
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JPH05301826A
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1991-12-24 |
1993-11-16 |
Snow Brand Milk Prod Co Ltd |
プロリルエンドペプチダーゼ阻害剤
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JPH05201970A
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1992-01-24 |
1993-08-10 |
Japan Tobacco Inc |
新規プロリン誘導体
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JP3318622B2
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1992-05-27 |
2002-08-26 |
独立行政法人産業技術総合研究所 |
プロリルエンドペプチダーゼ阻害剤
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GB9212308D0
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1992-06-10 |
1992-07-22 |
Ici Plc |
Therapeutic compositions
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GB9213215D0
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1992-06-20 |
1992-08-05 |
Wellcome Found |
Peptides
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JPH06116284A
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1992-10-02 |
1994-04-26 |
Yamanouchi Pharmaceut Co Ltd |
新規ペプチド
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1992-10-05 |
2000-07-15 |
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피리미딘 화합물
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1992-10-16 |
1993-11-09 |
Japan Tobacco, Inc. |
2-piperidinecarboxylic acid derivatives useful as NMDA receptor antagonists
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EP0670309A1
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1992-11-20 |
1995-09-06 |
Japan Tobacco Inc. |
Compound with prolyl endopeptidase inhibitor activity and pharmaceutical use thereof
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1992-12-16 |
1994-10-11 |
Japan Tobacco Inc. |
Benzomorphans useful as NMDA receptor antagonists
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JPH06192298A
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1992-12-24 |
1994-07-12 |
Mitsui Toatsu Chem Inc |
新規機能性ペプチド
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1993-01-20 |
1995-02-09 |
Thomae Gmbh Dr K |
Aminosäurederivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
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JPH06234693A
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1993-02-09 |
1994-08-23 |
Snow Brand Milk Prod Co Ltd |
新規イソテトラセノン系物質及びその製造法
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1993-02-15 |
1995-05-24 |
Sanofi Elf |
Composés à groupe sulfamoyle et amidino, leur procédé de préparation et les compositions pharmaceutiques les contenant.
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EP0611769A1
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1993-02-16 |
1994-08-24 |
Merrell Dow Pharmaceuticals Inc. |
Silylated acetylcholinesterase inhibitors
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1993-03-02 |
1994-09-26 |
Fujisawa Pharmaceutical Co., Ltd. |
Novel heterocyclic compound
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1993-03-03 |
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Rhone Poulenc Rorer Sa |
Application de dérivés de 2H-1,2-4-benzothiadiazine-3(4H)-one-1,1-dioxyde comme antagonistes non compétitifs du récepteur NMDA.
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FR2703050B1
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1993-03-24 |
1995-04-28 |
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Nouveaux dérivés bicycliques azotés, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
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EP0627400A1
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1993-06-04 |
1994-12-07 |
Merrell Dow Pharmaceuticals Inc. |
Aromatic acetylcholinesterase inhibitors
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1993-06-18 |
1995-01-05 |
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Neuropeptide y antagonists and agonists
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1993-06-30 |
1995-01-24 |
Zeria Pharmaceutical Co., Ltd. |
Thiazolidine derivative and medicine containing the same
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1993-07-16 |
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Rhone Poulenc Rorer Sa |
Dérivés d'imidazo[1,2-a]pyrazine-4-one, leur préparation et les médicaments les contenant.
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FR2707645B1
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1993-07-16 |
1995-08-11 |
Rhone Poulenc Rorer Sa |
Dérivés d'imidazo[1,2-a]pirazine-4-one, leur préparation et les médicaments les contenant.
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EP0709373B1
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1993-07-23 |
2001-10-17 |
Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai |
Pyrrolidine derivative
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1993-11-05 |
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Rhone Poulenc Rorer Sa |
Médicaments contenant des dérivés de 7H-imidazol[1,2-a]pyrazine-8-one, les nouveaux composés et leur préparation.
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1993-12-02 |
1997-09-22 |
Merrell Pharma Inc |
2-acylpyrrolidines; compounds, preparation and pharmaceutical compositions
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1993-12-03 |
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Ferring Bv |
Dp-iv inhibitors and pharmaceutical compositions containing them
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1994-03-28 |
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Dérivés de 5H-indeno[1,2-b]pyrazine-2,3-dione, leur préparation et les médicaments les contenant .
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1994-03-28 |
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Dérivés d'imidazo[1,2-a]indeno[1,2-e]pyrazine-4-one, leur préparation et les médicaments les contenant .
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1994-03-28 |
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1994-03-28 |
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JPH07267988A
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1994-03-31 |
1995-10-17 |
Yamanouchi Pharmaceut Co Ltd |
新規ペプチド
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1994-05-24 |
1994-07-13 |
Fisons Corp |
Novel therapeutic method
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1994-09-13 |
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Pfizer Ltd |
Therapeutic agents
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Eli Lilly And Company |
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1994-10-20 |
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1994-10-20 |
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Heterocyclic neuropeptide Y receptor antagonists
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1994-11-02 |
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Spiro heterocycle-imidazo(1,2-a)indeno(1,2-e)pyrazine)-4'- ones, leur preparation et les medicaments les contenants
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1994-12-29 |
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1995-01-11 |
1997-11-25 |
Hoechst Marion Roussel, Inc. |
Substituted oxazolidine calpain and/or cathepsin B inhibitors
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1995-01-12 |
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Modified peptides
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1995-05-26 |
1996-09-03 |
Warner-Lambert Company |
Sulfonylquinolines as central nervous system and cardiovascular agents
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1995-06-07 |
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Bristol-Myers Squibb Company |
Dihydropyridine NPY antagonists: nitrogen heterocyclic derivatives
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Dihydropyridine npy antagonists: piperazine derivatives
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Bristol-Myers Squibb Company |
Dihydropyridine NPY antagonists: piperidine derivatives
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Indolyl neuropeptide Y receptor antagonists
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Warner-Lambert Company |
Method for treating and preventing inflammation and atherosclerosis
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Aminosäurederivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
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1995-11-30 |
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Aminosäurederivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
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1995-11-30 |
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Aminosäurederivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
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Aryl sulfonamide and sulfamide derivatives and uses thereof
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Heteroaryl compounds
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Novartis Ag |
Quinazolin-2,4-diazirines as npy receptor antagonist
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Receptor antagonists
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1997-06-27 |
Novartis Ag |
Heteroaryl derivatives
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1995-12-12 |
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Yamanouchi Pharmaceut Co Ltd |
新規アミノ酸誘導体
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Warner Lambert Co |
2-Substituted piperidine analogs and their use as subtypeselective nmda receptor antagonists
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1995-12-22 |
1997-06-24 |
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4-Substituted piperidine analogs and their use as subtype selective nmda receptor antagonists
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1995-12-22 |
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4-Subsituted piperidine analogs and their use as subtype selective nmda receptor antagonists
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1998-10-21 |
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Benzimidzolyl neuropeptide y receptor antagonists
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