MY103943A - Orthorhombic ciclosporin crystal form, process for its production and pharmaceutical compositions containing it - Google Patents

Orthorhombic ciclosporin crystal form, process for its production and pharmaceutical compositions containing it

Info

Publication number
MY103943A
MY103943A MYPI88001495A MYPI19881495A MY103943A MY 103943 A MY103943 A MY 103943A MY PI88001495 A MYPI88001495 A MY PI88001495A MY PI19881495 A MYPI19881495 A MY PI19881495A MY 103943 A MY103943 A MY 103943A
Authority
MY
Malaysia
Prior art keywords
ciclosporin
crystal form
production
pharmaceutical compositions
orthorhombic
Prior art date
Application number
MYPI88001495A
Other languages
English (en)
Inventor
Uike Yasuyuki
Danielle Giron Dr
Martin List Dr
Hans Peter Weber Dr
Friedrich Richter Dr
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MY103943A publication Critical patent/MY103943A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/645—Cyclosporins; Related peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
MYPI88001495A 1987-12-21 1988-12-21 Orthorhombic ciclosporin crystal form, process for its production and pharmaceutical compositions containing it MY103943A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13623087A 1987-12-21 1987-12-21
US17261388A 1988-03-24 1988-03-24
US21254888A 1988-06-28 1988-06-28

Publications (1)

Publication Number Publication Date
MY103943A true MY103943A (en) 1993-10-30

Family

ID=27384838

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI88001495A MY103943A (en) 1987-12-21 1988-12-21 Orthorhombic ciclosporin crystal form, process for its production and pharmaceutical compositions containing it

Country Status (27)

Country Link
JP (1) JPH0791316B2 (da)
KR (1) KR100188305B1 (da)
AT (1) AT403163B (da)
AU (1) AU626274B2 (da)
BE (1) BE1002665A4 (da)
CA (1) CA1341396C (da)
CH (1) CH677926A5 (da)
CY (1) CY1799A (da)
DE (1) DE3843054C2 (da)
DK (1) DK175220B1 (da)
ES (1) ES2012580A6 (da)
FI (1) FI89065C (da)
FR (1) FR2624863B1 (da)
GB (1) GB2211848B (da)
GR (1) GR1002486B (da)
HK (1) HK102894A (da)
HU (1) HU203564B (da)
IE (1) IE62006B1 (da)
IL (1) IL88719A0 (da)
IT (1) IT1235356B (da)
LU (1) LU87409A1 (da)
MY (1) MY103943A (da)
NL (1) NL195096C (da)
NO (1) NO177228C (da)
NZ (1) NZ227384A (da)
SE (1) SE503174C2 (da)
SG (1) SG99494G (da)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639724A (en) * 1984-07-24 1997-06-17 Sandoz Ltd. Cyclosporin galenic forms
US6007840A (en) * 1988-09-16 1999-12-28 Novartis Ag Pharmaceutical compositions comprising cyclosporins
KR0148748B1 (ko) 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 사이클로스포린을 함유하는 약학조성물
US7081445B2 (en) 1989-02-20 2006-07-25 Novartis Ag Cyclosporin galenic forms
US5294604A (en) * 1989-12-20 1994-03-15 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Method of treating ocular diseases by periocular administration of cyclosporine A or G
GB9105705D0 (en) * 1991-03-18 1991-05-01 Sandoz Ltd Improvements in or relating to organic compounds
US6262022B1 (en) 1992-06-25 2001-07-17 Novartis Ag Pharmaceutical compositions containing cyclosporin as the active agent
HK1004520A1 (en) * 1992-05-13 1998-11-27 Novartis Ag Ophthalmic compositions containing a cyclosporin
PT589843E (pt) 1992-09-25 2002-04-29 Novartis Ag Composicoes farmaceuticas contendo ciclosporinas
SK164796A3 (en) 1994-11-03 1997-06-04 Dresden Arzneimittel Novel cyclosporine preparation forms for oral administration of and process for producing them
US5766629A (en) 1995-08-25 1998-06-16 Sangstat Medical Corporation Oral cyclosporin formulations
US5962019A (en) * 1995-08-25 1999-10-05 Sangstat Medical Corporation Oral cyclosporin formulations
DE19544507B4 (de) 1995-11-29 2007-11-15 Novartis Ag Cyclosporin enthaltende Präparate
US6262054B1 (en) * 1996-02-01 2001-07-17 Sloan-Kettering Institute Of Cancer Research Combination therapy method for treating breast cancer using edatrexate
SK285019B6 (sk) 1997-01-30 2006-04-06 Novartis Ag Tvrdá želatínová tobolka
TW581681B (en) 1998-02-20 2004-04-01 Nektar Therapeutics Liquid crystal forms of cyclosporin
US7732404B2 (en) 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
DE602005011928D1 (de) 2004-01-20 2009-02-05 Allergan Inc Zusammensetzungen für die lokalisierte therapie des auges, vorzugsweise enthaltend triamcinolon-acetonid und hyaluronsäure
CN1763084B (zh) * 2005-10-11 2010-04-21 山东新时代药业有限公司 高纯度环孢菌素a的制备方法
MY180581A (en) * 2011-05-27 2020-12-02 Allergan Inc A crystalline form of cyclosporine a, methods of preparation, and methods for use thereof
BR112014011768A2 (pt) * 2011-11-15 2017-05-09 Allergan Inc forma 2 de ciclosporina a e método de produção da mesma
WO2013074610A1 (en) 2011-11-15 2013-05-23 Allergan, Inc. Sustained action formulation of cyclosporin form 2
EP3701939A1 (en) * 2011-11-15 2020-09-02 Allergan, Inc. Suspensions of cyclosporin a form 2
US20130123194A1 (en) * 2011-11-15 2013-05-16 Allergan, Inc. Autoclavable suspensions of cyclosporin a form 2
TW202430537A (zh) * 2022-10-20 2024-08-01 日商中外製藥股份有限公司 環狀胜肽的結晶的製造方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH614931A5 (da) * 1975-11-04 1979-12-28 Sandoz Ag
US4117118A (en) * 1976-04-09 1978-09-26 Sandoz Ltd. Organic compounds
CH640519A5 (en) * 1976-04-09 1984-01-13 Sandoz Ag Process for preparing a modified form of the antibiotic S 7481/F-1
DE2819094A1 (de) * 1977-05-10 1978-11-23 Sandoz Ag Cyclosporin-derivate, ihre verwendung und herstellung
CH637124A5 (en) * 1978-10-18 1983-07-15 Sandoz Ag Antibiotic, its preparation and use

Also Published As

Publication number Publication date
DE3843054C2 (de) 2003-08-21
GR880100850A (el) 1994-03-31
FR2624863B1 (fr) 1991-04-26
DK705488D0 (da) 1988-12-19
JPH01211598A (ja) 1989-08-24
BE1002665A4 (fr) 1991-04-30
ATA309588A (de) 1997-04-15
NL195096C (nl) 2004-02-09
NO885625L (no) 1989-06-22
NL8803125A (nl) 1989-07-17
CY1799A (en) 1995-02-17
GB2211848A (en) 1989-07-12
HUT49893A (en) 1989-11-28
DE3843054A1 (de) 1989-07-27
IT1235356B (it) 1992-06-30
HK102894A (en) 1994-09-30
AT403163B (de) 1997-11-25
CH677926A5 (da) 1991-07-15
SE503174C2 (sv) 1996-04-15
AU626274B2 (en) 1992-07-30
SE8804570D0 (sv) 1988-12-19
FI89065C (fi) 1993-09-30
IE883779L (en) 1989-06-21
NO177228B (no) 1995-05-02
SG99494G (en) 1994-10-28
ES2012580A6 (es) 1990-04-01
DK175220B1 (da) 2004-07-12
GR1002486B (el) 1996-12-09
HU203564B (en) 1991-08-28
DK705488A (da) 1989-06-22
IE62006B1 (en) 1994-12-14
FI885869L (fi) 1989-06-22
FI89065B (fi) 1993-04-30
SE8804570L (sv) 1989-06-22
IL88719A0 (en) 1989-07-31
KR100188305B1 (ko) 1999-06-01
FR2624863A1 (fr) 1989-06-23
FI885869A0 (fi) 1988-12-19
KR890009975A (ko) 1989-08-05
GB8829556D0 (en) 1989-02-08
JPH0791316B2 (ja) 1995-10-04
IT8848690A0 (it) 1988-12-20
NO885625D0 (no) 1988-12-19
NO177228C (no) 1995-08-09
GB2211848B (en) 1991-11-06
LU87409A1 (fr) 1989-07-07
CA1341396C (en) 2002-11-05
NZ227384A (en) 1991-09-25
AU2705588A (en) 1989-06-22

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